Podcasts about Icis

SINGAPORE (ICIS)--Asia PET resin prices have been shaped by volatile feedstock costs, while producer margins have narrowed to around breakeven levels. In this ICIS podcast, Senior Analyst Jimmy Zhang and Senior Editor Judith Wang discuss the impact of the US-Iran conflict on feedstock markets, the challenges facing Asia PET resin exports, and the outlook for the regional market. Upstream values remain a key driver of petrochemical price direction Limited vessel availability, high freight costs constrain Asia PET resin exports ICIS remains cautiously optimistic on PET resin supply-demand fundamentals

In the latest ICIS podcast, analysts Haiyan, Joanne and Amy discuss the outlook for China's PE market in H2 2026. The team explores how expanding supply, changing trade flows and demand uncertainties could shape the market in the months ahead.

In the latest ICIS podcast, analysts Haiyan, Joanne and Amy discuss the outlook for China's PE market in H2 2026. The team explores how expanding supply, changing trade flows and demand uncertainties could shape the market in the months ahead.

As European gas markets navigate a complex mix of geopolitical risk, storage concerns and shifting LNG flows, the outlook continues to evolve. ICIS has pushed its expectation for structurally tight market conditions out to October from August.At the same time, a moderate winter influenced by El Niño could provide some demand-side relief, even if significant uncertainties remain.Additional market concerns are emerging around potential regulatory intervention.In Germany, the prospect of government action if storage levels fall too low is attracting growing attention, while in Italy, market participants are assessing the possibility of measures to cap the PSV premium to the Dutch TTF benchmark.In this episode, ICIS global LNG editor Ed Cox, energy market reporter Ghassan Zumot and Gas in Focus deputy editor Marta Del Buono join ICIS energy and cross-commodity expert Aura Sabadus to unpack the key drivers shaping European gas and LNG markets, and what they could mean for prices, supply security and trading strategies in the months ahead.

As Moldova and Ukraine prepare to introduce mandatory bundled capacity rules at EU borders from August, the region's gas sector is entering a pivotal phase. The new framework promises significant change in terms of streamlining operations but concerns remain that underlying barriers, including licensing requirements, VAT obligations and trading restrictions, could limit competition and increase costs for market participants.In this episode, ICIS senior reporter Aura Sabadus speaks with Sergiu Lica, Head of Gas Trading at Energocom, Moldova's state-owned gas and electricity wholesaler, about the practical implications of the new rules for the country and the region. The discussion also examines the evolution of Moldova's gas market amid gradual deregulation for industrial consumers, as well as Energocom's preparations for the upcoming winter.  

Europe's chemical industry will become increasingly exposed to competition from China, the Middle East and the rest of Asia if more shippers return to the Suez Canal. Maersk, Hapag-LLoyd reopen one Gemini service through the Suez Canal China becomes increasingly self-sufficiency in chemicals Switches from net importer to exporter for some important products Growth of chemicals post-2030 could be focussed in megasites with low carbon production linked to CCS/U (carbon capture and storage/utilization) US ethane prices have fallen, giving US producers more of a competitive advantage Introduction of US-EU trade deal will see tariffs on many US chemical imports fall from 6.5% to zero Note – this podcast was recorded on 7 July, 2026In this ICIS Think Tank podcast, Will Beacham interviews ICIS senior consultant John Richardson and ICIS Insight Editor Tom Brown.

Europe's gas market is entering a new era in which transparency is becoming just as valuable as the resource itself. As policymakers tighten requirements around carbon emissions, methane monitoring and the gradual withdrawal from Russian gas, market participants are under growing pressure to prove not only the environmental footprint of their supplies but also their origin and compliance status. In this episode, ICIS energy and cross-commodity expert Aura Sabadus speaks with Simone Pugliese, CEO of Attributes, a pioneering digital platform helping to bring greater visibility and traceability to natural gas and LNG value chains. The discussion explores how the industry is adapting to an increasingly data-driven regulatory environment and whether energy markets are heading towards an all-in-one certification framework combining emissions, methane performance, origin and compliance credentials within a single trusted digital asset.

LONDON (ICIS)--A turbulent Q2 saw the phenol and acetone value chain rocked by geopolitical disruption, cost inflation and shifting supply-demand dynamics, with prices surging before easing as markets rebalanced.In this Q2 episode of the Acetone and Derivatives podcast, ICIS experts unpack the key drivers across phenol, acetone, BPA, epoxy and polycarbonate, and explore a cautious, uncertain outlook for Q3 amid weak demand, ample supply and ongoing global volatility.MMA markets editor Mathew Jolin-Beech is joined by Acetone and phenol editor Jane Gibson, Heidi Finch senior editor for the European BPA and epoxy resins, Sam Lovatt on PC, and Michele Bossi - analyst for the chain.

From March to May, China has exported record amounts of chemicals despite falling production as companies work through huge inventories built up over the past few years. China chemicals production has fallen, but exports are soaring Inventory levels in China are much higher than people suspected Higher prices mean that this is now being exported China operators still run despite poor economics, domestic demand They have been stockpiling, now selling this inventory May data confirm the trend is continuing 20% of global olefins supply has been disrupted by the Middle East war 45% of Asia ethylene supply outside of China was offline in April Record capacity additions mean oversupply will continue for 5-10 years From 2030 China will add less new capacity In this Think Tank podcast, Will Beacham interviews ICIS senior polyolefins analyst James Wilson and ICIS senior consultant John Richardson.

Season 4 has been anything but quiet, and the same can be said for the EU carbon market.With the EU ETS review fast approaching, we invited Lewis Unstead from ICIS to help us navigate one of the most consequential debates facing European climate policy. Is the With the EU ETS review fast approaching, we invited Lewis Unstead from ICIS to help us navigate one of the most consequential debates facing European climate policy. Is the EU ETS really to blame for industry's competitiveness challenges? Can the upcoming review address those concerns, or are policymakers looking in the wrong place? And when it comes to reform, who ultimately holds the pen?EU ETS really to blame for industry's competitiveness challenges? Can the upcoming review address those concerns, or are policymakers looking in the wrong place? And when it comes to reform, who ultimately holds the pen?From political red lines and carbon price expectations to the often-overlooked technical details that can move the market, this episode explores the questions shaping the future of the EU ETS, and why the answers matter far beyond the carbon market itself.Riham Wahba - Senior Market Analyst at Vertis Environmental Finance.Lewis Unstead - Senior analyst at ICISDisclaimer: https://legal.vertis.com/api/document/282/get_document/

JCO PO authors Dr. Matthew Campbell and Dr. Mohammad Moussa at The University of Texas MD Anderson Cancer Center and Baylor College of Medicine, Houston, Texas, share insights into their article, "Efficacy of Immune Checkpoint Blockade in Advanced Upper Tract Urothelial Cancer With DNA Mismatch Repair Deficiency or Microsatellite Instability." Host Dr. Rafeh Naqash and Drs. Campbell and Moussa discuss how the study findings suggest that dMMR/MSI-H may serve as a biomarker of sensitivity to single-agent ICIs in advanced UTUC. LINK TO FULL TRANSCRIPT

FUKUOKA, Japan (ICIS)--In this podcast, ICIS editors Josh Quah, Joy Foo, Ai Teng Lim and Jonathan Chou discuss the ongoing developments in Asia olefins and vinyls on the sidelines of Asia Petrochemicals Industry Conference (APIC) 2026 conference. The editors cover trends in ethylene, propylene, butadiene and polyvinyl chloride (PVC), as well as shifting trade flows across the region. With Chinese exports increasingly asserting a greater presence in Asia as an impact of the Mideast conflict, they discuss what this may mean for the immediate future of these products.   Unprecedented increase in Chinese olefin exports in March, April pressure markets amid demand drop-off PVC export markets contend with intensifying Chinese carbide PVC supply competition amid India monsoon season Temporary nature of Chinese exports called into question

SINGAPORE (ICIS)--Asian methyl methacrylate (MMA) markets continue to feel the impact of supply shocks seen in early March, with no near-term resolution in the Middle East conflict.Producers continue to grapple with costs from high-priced inventories built up during earlier panic buying, while struggling to pass these on to downstream buyers. This comes as easing feedstock conditions exert downward pressure on MMA prices.In this podcast, ICIS senior editor Jasmine Khoo joins us from the 2026 Asia Petrochemical Industry Conference (APIC) in Fukuoka Japan, to discuss challenges in derivative markets, rising Chinese spot export activity, and an overhang of existing inventories. Accumulated inventories in Mar-Apr deter buying as alternative feedstock routes add supply pressure Chinese spot activity gains traction as regional producers grapple with elevated costs Seasonal June lull, Mideast conflict, weak downstream confidence keep sentiment pessimistic

While Europe's long-term biomethane potential remains strong as output is projected to reach up to 35bcm by 2030, growth is being slowed by regulatory bottlenecks, permitting delays and feedstock constraints.At the same time, new policy developments are reshaping the outlook. Germany is tightening transport decarbonization rules while introducing more flexible pathways for renewable gases in heating. At the same time, policy fragmentation persists, highlighted by the European Commission's action against France over its certification scheme.So, what does this mean for the future role of biomethane in Europe's energy mix? Aura Sabadus has invited ICIS biomethane and power market specialist Andrea Battaglia to unpack the shifting landscape of Europe's biomethane market.

The closure of the Strait of Hormuz is having a severe and unprecedented effect on fertilizer supply because so much production is concentrated in the Middle East. -          If war drags on, danger of two-tier food economy developing with lower tier suffering shortages-          Poorer countries may be priced out of the fertilizer market-          Food impact will be seen later this year and into 2027-          Unique situation because fertilizer supply is very concentrated around the Strait of Hormuz, so the effect is amplified-          Global ammonia, sulphur markets heavily impacted by the Iran war-          Carbon Border Adjustment Mechanism (CBAM) applies carbon tax on EU imports  -          It will replace free allocations under Emissions Trading Scheme (ETS)-          As imports become more expensive, downstream sectors argue they suffer raised raw material costs-          Proposal to suspend CBAM on fertilizers In this ICIS Think Tank podcast, Will Beacham interviews ICIS ammonia reporter Sylvia Tranganida, ICIS ammonia analyst Bee Lin Chow, ICIS sulphur reporter Manuja Pandey, ICIS phosphatic fertilizer reporter Chris Vlachopoulos and ICIS data analyst Grégoire Ladouce. 

Please visit answersincme.com/860/102771731-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Sairah Ahmed, MD; and Sharon Marie Castellino, MD, MSc. In this activity, experts in Hodgkin lymphoma discuss unmet needs and emerging data in the treatment of classical HL. Upon completion of this activity, participants should be better able to: Explain the rationale for investigating ICI-based regimens for previously untreated advanced cHL; Interpret the emerging clinical evidence for ICI-based regimens in patients with previously untreated advanced cHL; and Propose how emerging ICI-based regimens, as they become available, may fit into the treatment paradigm for adult and pediatric patients with previously untreated advanced cHL.

CME credits: 0.25 Valid until: 08-05-2027 Claim your CME credit at https://reachmd.com/programs/cme/redefining-immunotherapy-access-integrating-subcutaneous-checkpoint-inhibitors-across-solid-tumors/56117/ This interview-style activity brings together a physician and nurse to explore the scientific rationale and clinical evidence behind subcutaneous (SC) immune checkpoint inhibitors (ICIs) in solid tumors. Through discussion of key clinical trials, they highlight pharmacokinetic equivalence, efficacy, and safety data compared with intravenous delivery. The conversation also offers practical insights for integrating SC ICIs into clinical workflows—including patient selection, administration techniques, and management of immune-related adverse events—while considering potential benefits for patient experience, nursing practice, and healthcare resource use.=

Join the ICIS European Recycling Team as they discuss the key topics and takeaways they hope to get from this year's Plastics Recycling Show Europe (PRSE) taking place in Amsterdam on 5-6 May.  You can meet the Europe Recycling Team at the ICIS Booth in Hall 5, Stand F110, where you can scan a QR code to get access to the latest ICIS data on the recycling markets and learn more about ICIS' sustainability offerings. 

SHANGHAI (ICIS)--Since the outbreak of the Middle East conflict in late February, attention has increasingly focused on its impact on energy and petrochemical markets. A steep rise in crude oil and naphtha prices has driven a rapid increase in prices across aromatics and their derivatives. According to ICIS data, as of 22 April, prices of downstream polymer products derived from aromatics in China, including polyester fibre, polyethylene terephthalate (PET), acrylonitrile butadiene styrene (ABS), polystyrene (PS) and expandable polystyrene (EPS) have risen by 25–40% compared with pre‑conflict levels.This inevitably raises questions about whether end-industry companies can withstand such immense price pressure, what their current countermeasures are, and how these dynamics may feed back into upstream markets.In this podcast, Asian Senior Aromatics Analysts Jenny Yi, Jimmy Zhang, and Yoland Chen discuss how the Middle East conflict is affecting demand across China's aromatics end-use industries and share their views on near- and medium-term implications.The 38th China International Plastics & Rubber Industry Exhibition (Chinaplas) - the world's leading trade fair for the sector - is taking place from April 21 to 24 April in Shanghai, China. ICIS held extensive discussions with market participants attending the event, with key insights shared in today's podcast. End-use industry performance is mixed: nylon, PET resin demand grows, home appliance demand slows, textile and clothing demand may decline ABS demand growth in China is expected to be lower this year than in 2025, while EPS and PS demand is forecast to slow in 2026 before rebounding in 2027 China's polyester fiber consumption and production are set to decline this year, while PET resin demand remains strong, prompting integrated producers to prioritize PET resin output

Asian propylene (C3) supply has been shrinking with the ongoing shipping disruption through the Strait of Hormuz amid the US-Israel-Iran conflict. Supply tightness is expected to persist and support the market as feedstock availability and cost pressure remain key problems, weighing down regional plants' operating rates. Downstream demand and end-use consumption, however, are facing greater uncertainties as the geopolitical tensions weaken the global economic outlook, which could cloud the upside potential of propylene.In this podcast, ICIS editors Seymour Chenxia and Joy Foo, together with ICIS senior analyst Joey Zhou, Doris He and Lillian Ren revisit Asian propylene price trends since the Middle East conflicts, discuss price forecast, supply/demand conditions and outlook and trade flow changes. 

Since Russia sharply reduced gas supplies to Europe in 2022, Poland has emerged as a key regional gas crossroads, underpinned by its Swinoujscie LNG terminal, expanded interconnections and access to Baltic and North Sea supplies.Gas grid operator Gaz‑System has strengthened this role through infrastructure upgrades, tariff reforms and the repurposing of the Yamal pipeline from Germany into a west‑to‑east corridor. As other transport routes take shape across central and eastern Europe and global gas markets remain volatile, the focus is now on whether Poland can draw sufficient interest for its planned Gdansk LNG terminal and expanded export capacity, including flows to Ukraine.Speaking to ICIS senior reporter Aura Sabadus, Agnieszka Ozga, director for energy transition, and Stanislaw Brzeczkowski, chief engineer at Gaz‑System, explained the steps that are taken to position Poland as a major transshipment hub.

SINGAPORE (ICIS)--The ongoing US and Israel-led conflict in the Middle East has disrupted crucial flows of naphtha feedstock to cracker operators across Asia.With about 60% of Asia's naphtha imports typically sourced from the Middle East, the region remains vulnerable to widespread cracker run‑rate cuts and temporary shutdowns, with the effect cascading through the ethylene (C2) value chain. Naphtha shortages force Asia producers to cut C2, PE op rates Market participants look to China for alternative SM supply amid tightening availability PVC margins hold firm on adequate inventories, steady downstream demand This is the second installment of a two-part podcast.In part one, ICIS senior editors Josh Quah and Izham Ahmad examine how tightening feedstock availability is pressuring cracker operating rates and reshaping sentiment in the C2 and polyethylene (PE) markets.In part two, ICIS senior editor Luffy Wu and ICIS market analyst Jonathan Chou discuss how the disruption is filtering downstream into the styrene monomer (SM) and polyvinyl chloride (PVC) markets, and what participants can expect in the weeks ahead.

Please visit answersincme.com/KWA860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Benjamin Levy, MD, FASCO. In this activity, an expert in oncology discusses the use of subcutaneous immune checkpoint inhibitors. Upon completion of this activity, participants should be better able to: Describe the rationale for subcutaneous (SC) immune checkpoint inhibitor (ICI) administration in the context of standard care with intravenous (IV) formulations in patients with advanced solid tumors; Review the evidence for SC formulations of ICIs compared with IV formulations in patients with advanced solid tumors; and Propose patient-centered strategies for enhancing care with SC administration of ICIs in patients with advanced solid tumors.

Please visit answersincme.com/KWA860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Benjamin Levy, MD, FASCO. In this activity, an expert in oncology discusses the use of subcutaneous immune checkpoint inhibitors. Upon completion of this activity, participants should be better able to: Describe the rationale for subcutaneous (SC) immune checkpoint inhibitor (ICI) administration in the context of standard care with intravenous (IV) formulations in patients with advanced solid tumors; Review the evidence for SC formulations of ICIs compared with IV formulations in patients with advanced solid tumors; and Propose patient-centered strategies for enhancing care with SC administration of ICIs in patients with advanced solid tumors.

Energy markets were jolted into crisis after war erupted in the Middle East on 28 February, abruptly ending expectations of a calm year marked by abundant oil and gas supply and falling prices.As the conflict escalated, energy infrastructure across the Gulf came under attack and shipping through the Strait of Hormuz ground to a halt amid sharply rising security risks.Oil and gas prices have since doubled, while market volatility remains exceptionally high. Key questions now loom large. How will European policymakers respond? At what point will sustained high prices begin to trigger meaningful oil and gas demand destruction in Asia?To answer all these, senior journalist Aura Sabadus has invited ICIS global LNG editor Ed Cox, crude oil editor Barney Gray and head of gas analytics Andreas Schroeder for a forward-looking discussion. 

Europe sources far less of its chemical feedstocks from the Middle East than Asia, meaning it is more insulated from the direct impact of the war. -          Europe naphtha markets much less dependent on Middle East than Asia-          Europe only gets 30% of its crude from the Middle East compared to 60% for Asia-          Opening of INEOS Project ONE ethane-based cracker may force closure of naphtha-fed crackers-          Oil product markets have tightened faster than crude-          Margins for oil refineries which can access crude oil are rising -          Alternatives to bypass Strait of Hormuz limited – maximum 5 million barrels/day compared to 20 million barrels/day before the conflict -          ICIS forecasts crude oil demand growth will plateau from 2028-          Petrochemicals, aviation fuel will drive demand growth-          Most advantaged refineries combine good feedstock supply, flexibility and market access-          Other refineries will have to adopt innovative strategies to survive and thriveIn this ICIS Think Tank podcast, Will Beacham interviews ICIS senior analysts David Jorbenaze and Paolo Scafetta.  

The US-Israeli led war against Iran has unleashed extreme volatility across energy markets, with natural gas prices rising as much as 70% in the first ten days of March.Traders fear that the longer the shortfall lasts the more difficult it will become to refill gas stocks.While the fog of war remains thick in Iran and the Gulf, traders are struggling to get clarity and some degree of predictability. To find out how they navigate this situation and how events are seen by LNG traders, ICIS reporter Aura Sabadus caught up with James O'Brien, head of LNG at D.Trading, the trading arm of leading Ukrainian oil, gas and electricity private producer DTEK, and Luca Palmeri, CEO and founder of MCND, a dedicated consultancy, and himself a former senior LNG trader.

Europe's single market is widely regarded as the jewel in the crown of EU integration. However, the energy crisis of 2022 showed that its electricity and gas markets remain fragmented, exposing the bloc to economic and security risks. Cracks are felt in the day-to-day work of producers, traders, suppliers and end consumers as they struggle with complex red tape and high costs.ICIS highlighted some of these challenges in a recent white paper. A report published by Energy Traders Europe on 24 February highlights the constraints and the possible solutions to deepening the EU electricity and gas markets.As the need to create an Energy Union is now at the top of policymakers' agenda, ICIS reporter Aura Sabadus speaks to Mark Copley, CEO of Energy Traders Europe, and ICIS EU policy expert, Gretchen Ransow, about solutions to achieve consistency and alignment across the bloc and with neighbouring countries.

In this episode, Dr. Madeline O'Sullivan discusses her retrospective study of U.S. veterans in the Veterans Health Administration, examining outcomes among patients with rheumatoid arthritis treated with immune checkpoint inhibitors for cancer. She explains how the cohorts were defined, how use and timing of immunosuppressive therapies were analyzed, and how mortality and cause of death were determined. Dr. O'Sullivan summarizes the patient population, cancer types represented, and key findings on survival differences between RA and non-RA groups, as well as insights from secondary analyses and important study limitations. She also reflects on balancing research with clinical training, the mentorship that supported her work, lessons learned, and practical advice for trainees aiming to complete and publish research projects. 

In this podcast, experts Drs. Hope Rugo, Alison Conlin, Marleen Kok and Heather McArthur discuss results of recent pivotal clinical trials and their impact on current and evolving treatment paradigms for patients with metastatic triple-negative breast cancer.

On January 20th, Women in Chemicals started off the new year with a chemical markets outlook! Watch this recorded presentation on the current state of the chemical industry from the team at ICIS (Independent Commodity Intelligence Services), State of the Industry with ICIS, to get insights on the economic forecasts, supply chain challenges, and sustainability trends that will define the chemical industry in 2026.

Lithuania's offshore Klaipeda LNG terminal had a record year in 2025, with the port's utilisation rate soaring well above the EU average. Operator KN Energies anticipates an even better year in 2026. It has launched an open season for long-term capacity and is expecting more central and eastern European companies to use its services as they are looking for a diversity of sources and routes. Although traders are incentivised by Klaipeda's ease of doing business and transparency, they also flag limitations related to regional market liquidity and high regional transmission tariffs. In this interview, Darius Silenskis, CEO of KN Energies, tells ICIS reporter Aura Sabadus about the company's short and long-term plans and its role in supporting market liquidity. 

The EU's biomethane market has been developing at speed.Since 2023, production has risen more than 30% and the fuel is fast becoming not just an instrument to reach energy transition targets but is also making a real contribution to security of supply.A number of western European countries including France, Germany, Denmark, Italy, the UK are leading the way thanks to their extensive agricultural sectors and well designed subsidies schemes.However, building a single pan-European market is still a distant dream.ICIS energy news editor Andrea Battaglia tells senior reporter Aura Sabadus about the merits of this emerging sector but also the challenges that are slowing down progress.

Greenland has been holding the headlines in recent weeks as US President Donald Trump expressed an open interest in acquiring the world's largest island amid claims of security risks in the Arctic region.Many observers reject the argument, insisting the race to take over the resource-rich island and possibly even neighboring Canada is largely driven by economic considerations.Canada and Greenland already have long-standing security arrangements with the US and extracting more fossil fuels at a time when the world is already awash with oil and gas does not make sense.What, then, is driving the latest US policy in the Arctic region?ICIS senior journalist Aura Sabadus has invited Arctic expert Dr Petra Dolata, associate professor at the University of Calgary, Canada, to find out.

The US military operation in Venezuela at the start of 2026 resulting in the capture of president Nicolas Maduro had a modest immediate impact on oil prices. However, questions raised by these events are highly consequential for global markets and the future geopolitical power balance.Shares in some US-listed oil companies rose sharply after the operation, but who will be the real winners and losers in the long term? What are the implications for global oil and gas markets, amid protests rocking Iran and the possibility other resource-rich countries and territories such as Canada, Colombia, Greenland or Mexico could be on Washington's target list? Senior reporter Aura Sabadus has invited ICIS global crude oil editor Barney Gray and senior oil analyst David Jorbenaze to reflect on latest developments and the long-term outlook for markets.  

Delving into the latest JAHA review on immune checkpoint inhibitors and the heart has been illuminating

In this episode of Product & Packaging Powerhouse, host Megan Young Gamble recaps her experience at Makeup in New York 2025, from day 1 and this episode focusing on day two themes of packaging innovation, sustainability, and beauty tech. She shares actionable insights from industry panels including advances in sustainable packaging (like APC Packaging's patented mono-material droppers and refillable solutions), compliance considerations, smart packaging, and the importance of consumer psychology. Startup brand Rebel Queen's all-in-one curly hair product is highlighted for its minimalistic approach, while expert Roberta Sironi provides a masterclass on mascara packaging, launching an academy for deeper industry education. Megan ties it all together with observations on tech (especially AI's growing role in beauty and packaging), and offers advice for brands considering trade shows, encouraging startups to attend for valuable connections and inspiration. Be sure to check out Day 1 Recap HERE. Access our other podcast episodes mentioned during the episodeInside MakeUp in New York: Day 1 Innovation and Tech” with Megan Young Gamble. Listen HerePackaging Design, Influence, & Integrity" with Vicki Strull, Founder, Vicki Strull Design. Listen HereThe Truth About Stress, Skincare, and Your Immune System” with Dr. Ebru Karpuzoglu, Immunologist and founder of AveSeena and ChicScience Labs. Listen HereRoundtable: Packaging, Plastics & Platforms toward Circular Economy” with Emily Anne Friedman (Recycled Plastics Editor, ICIS), Ryan Fox (Packaging Analyst, Bloomberg Intelligence) and Nicole Toole (Founder of ECGO.) Listen HereHow Connected Packaging Shapes Sustainability and Traceability” with John Dwyer, Smart Packaging Expert at Smurfit Westrock & Maurizio Carano, Innovation & Marketing Director IML @ MCC Label. Listen HereAffiliate & Other Links: [Megan Young Gamble Links][AFFILIATE] Ready to crank out your content in as little as 5 minutes? Use Castmagic, AI powered tool to take your content creation from overwhelmed to overjoyed by saving hours of developing content. Save 20 hours by Signing up today! https://get.castmagic.io/Megan [FREEBIE] Learn about “day in the life” of a Packaging Project Manager → Get our “Starter Packaging PM Freebie” [link] https://glc.ck.page/thestarterpackagingprojectmanager [FREEBIE] Access commonly referenced organizations and tools in ONE PLACE with our handy guide HERE [link] https://bit.ly/OSTPlay Subscribe & Access our Video Vault YouTube Channel [ link] https://bit.ly/GLConYouTubeJoin our Email List [link] https://glc.ck.page/55128ae04b Follow and Connect with Megan on LinkedIn [link] https://linkedin.com/in/megangambleLearn about GLC, Packaging & Project execution firm for CPG brands http://www.getlevelconsulting.comWork with Me @ GLC, Schedule Discovery Call https://calendly.com/getlevelconsulting/15-minute-insight-sessionGot a topic you'd love us to cover? Share your ideas here [link] https://bit.ly/ppptopicformContact details of Jennifer Lehto, Senior Business Development Manager at APC PackagingLinkedin - https://www.linkedin.com/in/jenniferlehtoEmail id - jenniserl@apcpackaging.comRoberta Sironi, Chief Commercial Officer at Pibiplast SpaLinkedin - https://www.linkedin.com/in/roberta-sironi-0636982/Pibiplast academy - https://pibiplast.com/certificationsQuotes and Hooks:  We've always been very conscious about our scalp health because you have to make sure your scalp is clean to help with promoting hair growth.Smart packaging gives each product their own digital passport telling consumers what it is, where it came from and what to do at the end of life.Everybody wants sustainable packaging, but the real question is: what does sustainability mean to you and your brand?Glass is heavier, costs more to ship, and is prone to breakage, so is it really deemed sustainable? Something to think about.I struggled for years to find the perfect curly hair product and I finally created it, an all-in-one that hydrates, defines, and controls frizz. (Bleema, Rebel Queen)Mascara is a really complex product, you need a lot of technicity to make the magic and make the product work. (Roberta Cerroni, Pibi Plast)AI is here to stay, and I use ChatGPT as my daily assistant all the time to help me think through things and shorten cycle times.Would I attend Makeup In New York again? Absolutely. Is it a trade show that I would recommend any company to attend? Absolutely.

In this episode, we talk with Dr. Sharon about the complex intersection of oncology and autoimmunity through the lens of immune checkpoint inhibitors (ICIs)—therapies that have transformed cancer care but can also unleash immune-related adverse events (irAEs). Dr. Elad explains how ICIs work, why they can trigger autoimmune-like toxicities, and what distinguishes rheumatologic irAEs from classic autoimmune diseases. We explore the mechanistic overlaps between cancer immunotherapy and autoimmunity, the ethical and clinical dilemmas of balancing immune suppression with cancer control, and emerging biomarkers that may predict risk. Dr. Sharon also reflects on his career journey—from leading drug development efforts at the National Cancer Institute to returning to academia—and shares insights on collaboration, innovation, and the evolving partnership between oncologists and rheumatologists in managing these challenging conditions. 

Maintenance therapy with ICIs (atezolizumab or durvalumab) is already established in extensive stage small-cell lung cancer, but lurbinectedin enters the chat with a recent FDA approval. Next up - tarlatamab? IMforte (maintenance lurbinectedin + atezolizumab): https://doi.org/10.1016/S0140-6736(25)01011-6 DeLLphi-303 (phase 1b maintenance tarlatamab + ICI): https://doi.org/10.1016/S1470-2045(25)00480-2

In this JCO Precision Oncology Article Insights episode, Dr. Jiasen He summarizes JCO PO article "Synthetic Lethal Co-Mutations in DNA Damage Response Pathways Predict Response to Immunotherapy in Pan-Cancer" by Hua Zhong et al. TRANSCRIPT Jiasen He: Hello and welcome to the JCO Precision Oncology Article Insights. I am your host, Jiasen He, and today we will be discussing the JCO Precision Oncology article, "Synthetic Lethal Co-mutations in DNA Damage Response Pathway Predict Response to Immunotherapy in Pan-Cancer" by Dr. Zhang and colleagues. Immunotherapy has emerged as a groundbreaking treatment option for many types of cancer. However, the overall response rate to immunotherapy is low, around 10% to 30%. This highlights the critical need to identify which patients are most likely to benefit from immunotherapy. Two of the most extensively studied biomarkers are PD-L1 expression and tumor mutation burden (TMB). High levels of PD-L1 and TMB have been associated with better response to immune checkpoint inhibitors, which are now widely used in clinical practice. The predictive value of these markers is inconsistent across all settings. Some tumors with high PD-L1 or TMB still respond poorly to immunotherapy. One reason is that TMB reflects new antigen production, but recent studies suggest that new antigen levels do not always correlate with tumor immunogenicity. Many new antigens are not effectively recognized by T cells, limiting the immune response. Emerging evidence indicates that mutations in the DNA damage response (DDR) pathway play a critical role in moderating tumor immune interactions. Tumors harboring DDR pathways frequently exhibit increased genome instability, which may enhance their sensitivity to immune checkpoint inhibitors. While all these pathways are under active investigation, the optimal DDR pathway biomarkers for patient selection remain unclear. Notably, tumor cells with a defect in one DDR pathway may acquire greater reliance on alternative DDR pathways. Recent studies suggest that synthetic lethal co-mutations within DDR pathways are associated with immune-inflamed or hot tumor microenvironments. Based on this rationale, Dr. Zhang is investigating if synthetic lethal co-mutations in DDR pathway response pathway can serve as a treatment biomarker for immune checkpoint inhibitors. To address this question, Dr. Zhang and colleagues first utilized SynLethDB 2.0, a comprehensive database that integrated multiple data sets. Synthetic lethal (SL) gene pairs in this resource are identified through both experimental and computational approaches, with confidence scores assigned to each pair. These SL pairs were then mapped to gene sequencing results from several clinical cohorts. SL co-mutation status was defined as positive when both genes in a synthetic lethal pair were mutated. From this, SL co-mutation pairs specifically involving DDR pathway genes were selected. Patients were classified as DDR co-mutation positive if both genes in a synthetic lethal pair, each belonging to the defined DDR pathways, were mutated. In total, 431 DDR-related SL pairs were identified and matched to sequencing data from clinical cohorts. Clinical information was extracted from the cBioPortal, while further analysis of immune infiltration was performed using DNA mutation and RNA expression data from The Cancer Genome Atlas (TCGA) pan-cancer data set. The author first examined the correlation between SL co-mutation status and response to ICI therapy. They discovered that patients with SL co-mutation showed significantly improved outcome to ICI therapy across various clinical cohorts. Notably, in patients who did not receive ICI treatment, patients with SL co-mutation showed markedly compromised overall survival. Further analysis focused on the predictive value of SL co-mutation within DDR pathway genes. The author found that patients with DDR SL co-mutation had a longer overall survival compared to those with mutations in a single DDR gene, implying that SL co-mutations may be more effective biomarkers within the DDR pathway. To explore this further, in the TMB-MSKCC cohort, the author found that patients with DDR co-mutation constituted approximately 20% of various cancer types, including non-small cell lung cancer, melanoma, and bladder cancer. These patients demonstrated significantly better survival outcomes and disease control rates when treated with ICIs compared to DDR co-mutation negative patients. Notably, the TMB level was substantially higher in patients with DDR co-mutation, a finding consistent with data from the Miao-lung cohort. Furthermore, in cohorts not treated with ICIs, patients with DDR co-mutation had a shorter overall survival compared to their counterparts. Upon stratifying by PD-L1 expression, the author observed that patients with DDR co-mutation who were also PD-L1 positive derived the greatest clinical benefit from ICI therapy. Upon analyzing the frequency of co-mutation within the DDR pathway, the authors found that patients with SL co-mutation in the CPF-CPF pathway experienced remarkable survival benefit from ICIs. Within this group, one of the most common co-mutation combinations was TP53-ATM, observed in approximately 45% of cases, which was associated with a better response to ICI therapy. Further analysis of immune cell infiltration revealed that patients with TP53-ATM co-mutation exhibited a distinct tumor immune microenvironment. As the authors stated, the study's main limitation lies in the nature of retrospective analysis, which lacked the control over confounding variables and was subject to non-random sampling. For instance, patients with both SL co-mutations and DDR SL co-mutations exhibited high TMB, and TMB was known to be associated with improved response to ICI therapy itself. So, these findings require validation through prospective studies, and immune infiltration analysis needs confirmation via laboratory experiments. In conclusion, the authors found that patients with SL co-mutations in DDR pathways showed favorable clinical response and prolonged survival following ICI therapy. They also identified TP53-ATM co-mutations as a clinically relevant biomarker for predicting ICI treatment response. Thank you for tuning in to JCO Precision Oncology Article Insights. Don't forget to subscribe and join us next time as we explore more groundbreaking research shaping the future of oncology. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.   Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.  

In this special roundtable episode of the Product and Packaging Powerhouse, host Megan Young Gamble sat down with industry experts Emily Anne Friedman (Recycled Plastics Editor, ICIS), and Ryan Fox (Packaging Analyst, Bloomberg Intelligence) and Nicole Toole (Founder of ECGO) to unpack definitions of sustainability, the impact of data and technology, consumer education, and policy approaches like EPR. The panel considers how to move toward a more circular economy, while acknowledging the real-world constraints of infrastructure, cost, and market incentives.Affiliate & Other Links: [Megan Young Gamble Links][AFFILIATE] Ready to crank out your content in as little as 5 minutes? Use Castmagic, AI powered tool to take your content creation from overwhelmed to overjoyed by saving hours of developing content. Save 20 hours by Signing up today! https://get.castmagic.io/Megan [FREEBIE] Learn about “day in the life” of a Packaging Project Manager → Get our “Starter Packaging PM Freebie” [link] https://glc.ck.page/thestarterpackagingprojectmanager [FREEBIE] Access commonly referenced organizations and tools in ONE PLACE with our handy guide HERE [link] https://bit.ly/OSTPlay Subscribe & Access our Video Vault YouTube Channel [ link] https://bit.ly/GLConYouTubeJoin our Email List [link] https://glc.ck.page/55128ae04b Follow and Connect with Megan on LinkedIn [link] https://linkedin.com/in/megangambleLearn about GLC, Packaging & Project execution firm for CPG brands http://www.getlevelconsulting.comWork with Me @ GLC, Schedule Discovery Call https://calendly.com/getlevelconsulting/15-minute-insight-sessionGot a topic you'd love us to cover? Share your ideas here [link] https://bit.ly/ppptopicform [Powerhouse Guests Social Links]  1. Emily Anne Friedman - Recycled Plastics Senior Market Editor, Americas ICISLinkedIn: https://www.linkedin.com/in/emilyannefriedman/Company Website: https://www.icis.com/explore/2. Nicole Toole - Founder & CEO at ECGOLinkedIn: https://www.linkedin.com/in/nicole-toole/Company website: https://www.ecgo.co/3. Ryan Fox - Corrugated Packaging Market Analyst at Bloomberg Intelligence Linkedin : https://www.linkedin.com/in/ryandfox/Company website: https://www.green-markets.com/BOX/Index.htmlAdditional Resource: Pizza box recycling - https://www.westrock.com/blog/pizza-box-recycling Here's a great resource to help understand curbside recycling trends. - https://recyclingpartnership.org/residential-recycling-report/ [Podcast] Be a Packaging Steward": Packaging Sustainability, Sales and Intentional Connections with Adam Peek “Packaging Pastor” SVP of Meyers | Host of People of Packaging Podcast. Listen here[Podcast] How Connected Packaging Shapes Sustainability and Traceability” with John Dwyer, Smart Packaging Expert at Smurfit Westrock & Maurizio Carano, Innovation & Marketing Director IML @ MCC Label. Listen hereEpisode Quotes:.It's one thing to give someone a recycling bin, it's another thing for them to actually treat it like one. - EmilyYour PCR, which is post-consumer recycled content, is very important, but you also have to ask, where is that recycled material coming from and what's the overall carbon footprint? - EmilyUltimately when we think about shifting people's behavior, it's adopting the values of waste stewardship and ensuring products have the best end-of-life process. - NicoleThe biggest barriers are incentives and confusion, so we built technology to make it easy, local, and rewarding. - NicoleEvery year, corrugated captures about 35 million tons of old containers and turns them into a brand-new version that circularity is sustainability. - RyanOne of the challenges is inspiring people at home to take a bigger role in recycling. That's where the biggest difference will come. - RyanSometimes the greenest thing from a greenhouse gas perspective is actually plastic, but it's the one that gets hit the hardest. - Ryan

In this podcast, experts Virginia Kaklamani, MD, DSc, and Tiffany A. Traina, MD, FASCO, discuss the rationale for and data to support combining TROP2-targeting antibody-drug conjugates (ADCs) with immune checkpoint inhibitors (ICIs) to treat triple-negative breast cancer (TNBC).

Нещодавні удари України по трубопроводу «Дружба» — це не тільки атака на військову економіку Росії. Це також тривожний сигнал для угорцівАвтор: Ора Сабадус, старший журналіст із енергетичних питань Незалежної Комерційної Служби розслідувань (ICIS), кандидат наукНачитала: Наталія Чекаль 

BUFFALO, NY – June 20, 2025 – A new #review was #published in Volume 16 of Oncotarget on June 10, 2025, titled “Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors.” In this paper, led by first author Helen Qian and corresponding author Crismita Dmello from Northwestern University Feinberg School of Medicine, researchers compiled growing evidence that the CHEK2 gene, long known for its role in repairing DNA damage, may also influence how tumors respond to immunotherapy. Their analysis suggests that problems in CHEK2 function might make cancer cells more vulnerable to immune system attacks, highlighting a new opportunity to improve treatment outcomes in solid tumors. Immune checkpoint inhibitors (ICIs) have transformed cancer treatment; however, they are effective in only a subset of patients. This review suggests that tumors with reduced CHEK2 activity may accumulate more mutations that produce signals the immune system can recognize. These signals, known as neoantigens, help immune cells identify and destroy cancer cells more effectively. The review connects this process not only to CHEK2's established role in the DNA damage response but also to a newly proposed function in shaping the immune environment of tumors. CHEK2 normally helps maintain genomic stability by enabling precise DNA repair. When this function is lost, cells rely on more error-prone repair methods, leading to additional mutations. These mutations can increase tumor mutational burden, which has been linked to better outcomes with immunotherapy. Beyond DNA repair, the review highlights a second mechanism: activation of the cGAS-STING pathway. This pathway detects fragments of damaged DNA and triggers inflammation that attracts immune cells to the tumor. The authors highlight studies where CHEK2-deficient tumors responded better to PD-1 inhibitors, a common type of immune checkpoint inhibitor. In both lab models and early-stage clinical settings, CHEK2 loss was associated with increased infiltration of CD8+ T cells—immune cells essential for attacking cancer cells. In cancers such as glioblastoma and renal cell carcinoma, which are typically resistant to immunotherapy, reduced CHEK2 expression was linked with more favorable immune activity and higher expression of interferon-related genes. The compiled evidence points to CHEK2 as a potential biomarker for identifying patients likely to respond to immunotherapy. In addition, combining CHEK2 inhibitors with existing immunotherapies may enhance anti-tumor effects, particularly in cancers with limited treatment options. The review notes that some clinical trials using the CHEK1/2 inhibitor prexasertib alongside immune checkpoint therapies have already shown promising early results. “The initial results from this Phase I clinical trial support the immunomodulatory role of CHEK2 expression and even suggest CHEK2 potentiates immunosuppression.” Although more research is needed to confirm these mechanisms and improve treatment approaches, this review underscores the expanding role of DNA repair genes like CHEK2—not only in maintaining genome integrity but also in helping the immune system fight cancer. DOI - https://doi.org/10.18632/oncotarget.28740 Correspondence to - Crismita Dmello - stellacpak@outlook.com Video short - https://www.youtube.com/watch?v=C26pEBc0itk Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Is China's strategic push for chemical self-sufficiency reshaping the global petrochemical landscape? John Richardson, senior consultant at ICIS, joins The Chemical Show to share insights on how misjudged growth expectations for China, shifting demographics, and the rise of state-driven capacity expansions have led to the deepest, longest downturn in industry history. John and host Victoria Meyer examine why capacity was built around hopes for perpetual strong Chinese demand, only for real estate and demographic headwinds to alter the trajectory—creating a world of oversupply, negative margins, and mounting uncertainty. Their conversation covers the ongoing impact of trade tensions, the real drivers behind Chinese investment decisions, and why shutting down uneconomical assets is becoming a pressing necessity, especially in Europe and Asia. John and Victoria also weigh the challenges and promises of AI and data intelligence in a conservative, data-guarded sector, and offer advice for industry leaders navigating persistent market disruption. For chemical professionals, these perspectives highlight why adaptability, intelligence, and innovation will be critical in mastering both today's volatility and tomorrow's opportunities. Discover more about the following topics: How China's pivot from growth to self-sufficiency is reshaping global petrochemicals. Why chemicals face their worst business cycle ever, with Asian producers bleeding money on polyethylene. How tariffs and shifting policies create constant uncertainty for chemical companies. Why China's government-backed enterprises compete on strategy, not just cost. How data and artificial intelligence will separate industry winners from losers. “We've all assumed that polymer sciences are, you know, composites and stuff and playing with the same basic molecules, but maybe not.”  — John Richardson 00:00 Chemical Industry Insights by John 06:08 Domestic Chemical Manufacturing Expansion 08:48 Polyethylene Margins: China vs. Middle East 11:31 Tariffs and Global Business Perspectives 14:43 China's Trade Resilience Amid Challenges 20:23 Data Sharing's Impact on AI 23:50 Debating Productivity's True Impact 26:34 AI: Industrial Revolution or Renaissance? 30:49 Innovative Multi-Pane Glass Advancements 31:43 Innovative, Stronger Glass Advances  Subscribe to The Chemical Show on YouTube  ***Don't miss an episode: Subscribe to The Chemical Show on your favorite podcast player.  ***Like what you hear? Leave a rating and review. ***Want more insights? Sign up for our email list at https://www.thechemicalshow.com 

Last week I moderated the Truth in Beauty Panel, Surfactants Edition, at the 15th ICIS World Surfactants Conference, brought to you by the Independent Beauty Association. This episode features that conversation! How has misinformation impacted the surfactants sector? Disclaimer - surfactants are chemicals that are fundamental for much of what we have become accustomed to societally, from transportation to infrastructure and more. In cosmetics, they enable many of the different product formats, such as lotions and cleansing products. The panel included Dennis Abbeduto from Colonial Chemical, Claire Mcgahan from Stepan Company and Women in Chemicals, and Neil Burns, who put on the conference with ICIS. Big thank you to Colonial Chemical for sponsoring IBA to help make this conversation happen! Disclaimer, we had some recording challenges at the conference so this was a re-record - for those in attendance, worth a second listen since we covered a bit more! Interested in supporting the podcast? Please share, subscribe and write a review! If it's accessible, we also have a Patreon which you can find at patreon.com/theecowell

In 2010, the Association for Information Systems formed a special interest group () to nurture an international community of academics that study the role of digital technologies in fostering environmentally, economically and socially sustainable development. Fifteen years later, we sit down with , the current SIGGreen president, to reflect on the progress we have made. What do we know about how digital technologies help greening our planet? What efforts in empirical, theoretical, and design work is still needed? Is our role to understand the role of digital technologies or do we need to push and enact change ourselves? We conclude that environmental questions and problems are now firmly on the radar screen of our discipline but more work needs to be done for information systems academics to transform the way we think about and use digital technologies.  Episode reading list Corbett, J., & Mellouli, S. (2017). Winning the SDG Battle in Cities: How an Integrated Information Ecosystem can Contribute to the Achievement of the 2030 Sustainable Development Goals. Information Systems Journal, 27(4), 427-461. Seidel, S., Recker, J., & vom Brocke, J. (2013). Sensemaking and Sustainable Practicing: Functional Affordances of Information Systems in Green Transformations. MIS Quarterly, 37(4), 1275-1299. Hasan, H., Ghose, A., & Spedding, T. (2009). Editorial for the Special Issue on IT and Climate Change. Australasian Journal of Information Systems, 16(2), 19-21. Watson, R. T., Corbett, J., Boudreau, M.-C., & Webster, J. (2011). An Information Strategy for Environmental Sustainability. Communications of the ACM, 55(7), 28-30. Jenkin, T. A., Webster, J., & McShane, L. (2011). An Agenda for 'Green' Information Technology and Systems Research. Information and Organization, 21(1), 17-40. Watson, R. T., Boudreau, M.-C., & Chen, A. J. (2010). Information Systems and Environmentally Sustainable Development:  Energy Informatics and New Directions for the IS Community. MIS Quarterly, 34(1), 23-38. Elliot, S. (2011). Transdisciplinary Perspectives on Environmental Sustainability: A Resource Base and Framework for IT-Enabled Business Transformation. MIS Quarterly, 35(1), 197-236. Kahlen, M., Ketter, W., & van Dalen, J. (2018). Electric Vehicle Virtual Power Plant Dilemma: Grid Balancing Versus Customer Mobility. Production and Operations Management, 27(11), 2054-2070. Gholami, R., Watson, R. T., Hasan, H., Molla, A., & Bjørn-Andersen, N. (2016). Information Systems Solutions for Environmental Sustainability: How Can We Do More? Journal of the Association for Information Systems, 17(8), 521-536. Corbett, J., & El Idrissi, S. C. (2022). Persuasion, Information Technology, and the Environmental Citizen: An Empirical Study of the Persuasion Effectiveness of City Applications. Government Information Quarterly, 39(4), 101757. Degirmenci, K., & Recker, J. (2023). Breaking Bad Habits: A Field Experiment About How Routinized Work Practices Can Be Made More Eco-efficient Through IS for Sensemaking. Information & Management, 60(4), 103778. Zeiss, R., Ixmeier, A., Recker, J., & Kranz, J. (2021). Mobilising Information Systems Scholarship For a Circular Economy: Review, Synthesis, and Directions For Future Research. Information Systems Journal, 31(1), 148-183. Haudenosaunee Confederacy. (2025). Values. . The Stakeholder Alignment Collaborative. (2025). The Consortia Century: Aligning for Impact. Oxford University Press. Hovorka, D. and Corbett, J. (2012) IS Sustainability Research: A trans-disciplinary framework for a ‘grand challenge”. 33rd International Conference on Information Systems, Orlando, Florida. Hovorka, D. S., & Peter, S. (2021). Speculatively Engaging Future(s): Four Theses. MIS Quarterly, 45(1), 461-466. Gümüsay, A. A., & Reinecke, J. (2024). Imagining Desirable Futures: A Call for Prospective Theorizing with Speculative Rigour. Organization Theory, 5(1), . Kotlarsky, J., Oshri, I., & Sekulic, N. (2023). Digital Sustainability in Information Systems Research: Conceptual Foundations and Future Directions. Journal of the Association for Information Systems, 24(4), 936-952. Gray, P., Lyytinen, K., Saunders, C., Willcocks, L. P., Watson, R. T., & Zwass, V. (2006). How Shall We Manage Our Journals in the Future?  A Discussion of Richard T. Watson's Proposals at ICIS 2004. Communications of the Association for Information Systems, 18(14), 2-41. Saldanha, T. J. V., Mithas, S., Khuntia, J., Whitaker, J., & Melville, N. P. (2022). How Green Information Technology Standards and Strategies Influence Performance: Role of Environment, Cost, and Dual Focus. MIS Quarterly, 46(4), 2367-2386. Leidner, D. E., Sutanto, J., & Goutas, L. (2022). Multifarious Roles and Conflicts on an Inter-Organizational Green IS. MIS Quarterly, 46(1), 591-608. Wunderlich, P., Veit, D. J., & Sarker, S. (2019). Adoption of Sustainable Technologies: A Mixed-Methods Study of German Households. MIS Quarterly, 43(2), 673-691. Melville, N. P. (2010). Information Systems Innovation for Environmental Sustainability. MIS Quarterly, 34(1), 1-21. Edwards, P. N. (2013). A Vast Machine. MIT Press. Meadows, D. H., Meadows, D. L., Randers, J., & Behrens, W. W. (1972). The Limits to Growth: A Report for the Club of Rome's Project on the Predicament of Mankind. Universe Books. Over the Hedge. (2006). . McPhearson, T., Raymond, C. M., Gulsrud, N., Albert, C., Coles, N., Fagerholm, N., Nagatsu, M., Olafsson, A. S., Niko, S., & Vierikko, K. (2021). Radical Changes are Needed for Transformations to a Good Anthropocene. npj Urban Sustainability, 1(5), .   

Tariffs are shaking up the global chemical industry this year, creating uncertainty and shifting longstanding trade routes in unexpected ways. Victoria Meyer is joined by Joseph Chang and Al Greenwood of ICIS Chemical Business to break down the latest round of tariffs, including the dramatic 145% rate on Chinese imports and the sweeping, if temporary, 10% baseline affecting nearly every other country. They analyze how chemical markets from the US to Europe and Asia are being impacted, exploring falling product prices, disrupted supply chains, and the broader economic pressures facing manufacturers and end users alike.  With insights into policy-driven chaos, shifting sourcing strategies, and the growing ripple effects on sectors like housing and automotive, this episode highlights why strategic scenario planning, supply chain transparency, and adaptability are more critical than ever for chemical leaders.  Get ready for an in-depth look at these topics this week: Exploring the 2025 tariff policies and how they are reshaping chemical trade flows The economic ripple effects of the tariff policies Supply chain resilience and why chemical companies must map their entire supply chains Energy market dynamics: what is benefitting US chemical producers and what are the challenges Strategic planning in uncertainty and navigating the 90-day tariff pause Killer Quote: "Look at your supply chains. Which products are you getting from Vietnam? Which products are you getting from lower tariff countries? And see where is the most advantageous supplier with the tariffs, and also look at product substitution... You have to be cognizant, not just of your supplies, but also your products. Which products could be affected by influx of displaced shipments?" - Al Greenwood  Subscribe to The Chemical Show on YouTube  ***Don't miss an episode: Subscribe to The Chemical Show on your favorite podcast player.  ***Like what you hear? Leave a rating and review. ***Want more insights? Sign up for our email list at https://www.thechemicalshow.com  Sponsored by:Canadian Petrochemical Summit: https://www.cdnpetrochemcialsummit.ca Join chemical industry leaders, innovators, and experts at the Canadian Petrochemical Summit—the premier event for advancing the future of Canada's petrochemical sector. Set in the Canadian Rocky Mountains from June 17-19 this event will help you stay ahead of the curve. See you in the Rockies.

In this episode we're diving deep into the fascinating world of carbon recycling with a trailblazer who's reshaping how we think about waste and sustainability. Our guest is Dr. Jennifer Holmgren, CEO of LanzaTech—a company on a mission to transform our biggest environmental challenge into an economic opportunity. LanzaTech is pioneering a process that takes industrial emissions—the kind of harmful gases that typically contribute to climate change—and recycles them into valuable products like fuels, fabrics, and everyday consumer goods. The concept might sound like science fiction, but it's already science fact. LanzaTech's technology captures carbon emissions from sources like steel mills, refineries, and even municipal solid waste, then feeds those emissions to specially engineered microbes. These microbes act like tiny factories, converting carbon pollution into useful materials. Imagine jet fuel made from industrial waste or yoga pants created from captured carbon—it's not just possible; it's happening. In fact, at the very end of 2024, LanzaTech received a holiday gift from the federal government: a $200 million award from the Dept. of Energy. In this episode, Jennifer and I discuss the path LanzaTech took, including raising $400 million and taking 13 years prior to commercializing its first product. We also touch on her personal journey from her birth in Colombia to her taking the helm at LanzaTech. As you'll hear, this isn't just about reducing emissions; it's about completely rethinking the role of waste in our economy. LanzaTech's vision is one where carbon is no longer a liability but an asset—a resource that can be reused and recycled, over and over again. It's a powerful example of how businesses can align profitability with purpose, and it's precisely the kind of story that inspires hope in these challenging times. So, whether you're an entrepreneur, an environmentalist, or just someone curious about the future of our planet, this is a conversation you won't want to miss.  Discussed in this episode Jennifer recommends reading Quiet by Susan Cain. LanzaTech awarded up to $200 million in federal cash from the DOE LanzaTech is backed by Khosla Ventures. More about Jennifer Holmgren, PhD Dr. Jennifer Holmgren is CEO of LanzaTech. Under her guidance, LanzaTech is developing a variety of platform chemicals and fuels, including the world's first alternative jet fuel derived from industrial waste gases. Given her integral role in the development of this alternative jet fuel, she is also a Director and the Chair of the LanzaJet Board of Directors.  Prior to LanzaTech, Jennifer was VP and General Manager of the Renewable Energy and Chemicals business unit at UOP LLC, a Honeywell Company. While at UOP, she was a key driver of UOP's leadership in low carbon aviation biofuels, and under her management, UOP technology became instrumental in producing nearly all the initial fuels used by commercial airlines and the military for testing and certification of alternative aviation fuel. Jennifer is the author or co-author of 50 U.S. patents and more than 30 scientific publications, and is a member of the National Academy of Engineering. In 2003, she was the first woman awarded the Malcolm E. Pruitt Award from the Council for Chemical Research (CCR). In 2010, she was the recipient of the Leadership Award from the Civil Aviation Alternative Fuels Initiative (CAAFI). In 2015, Jennifer and her team at LanzaTech were awarded the U.S. Environmental Protection Agency Presidential Green Chemistry Award, and she was awarded the BIO Rosalind Franklin Award for Leadership in Industrial Biotechnology. Jennifer was named as #1 of the 100 most influential leaders in the Bioeconomy in 2017 and received the Global Bioenergy Leadership Award in 2018, and the 2020 William C. Holmberg Award for Lifetime Achievement in the Advanced Bioeconomy. In 2021, she received the Edison Achievement Award and the Prix Voltaire Award. In 2022, she was included in ICIS's Top 40 Power Players ranking. Jennifer also has an honorary doctorate from Delft University of Technology. Jennifer is on the Governing Council for the Bio Energy Research Institute in India. The institute was set up by the DBT (Department of Biotechnology, Indian Government) and IOC (Indian Oil Corporation).  She also sits on the Advisory Council for the Andlinger Center for Energy and the Environment at Princeton University, the National Academies' Board on Energy and Environmental Systems (BEES), the External Advisory Committee for the Advanced Energy Technologies Directorate (AET) at Argonne National Laboratory, the Advisory Council for the Pacific Northwest National Laboratory (PNNL), the Halliburton Labs Advisory Board, the Universiti Teknologi PETRONAS International Advisory Council, and the Founder Advisory for The Engine, a venture capital fund built by MIT that invests in early-stage science and engineering companies.  Jennifer holds a B.Sc. degree from Harvey Mudd College, a Ph.D. from the University of Illinois at Urbana-Champaign and an MBA from the University of Chicago.

In this podcast episode, Dr. Jonathan H. Westover talks with with Alison Jones about gender diversity in the chemicals world compared to gender diversity in other STEM fields. Alison Jones (https://www.linkedin.com/in/alison-jones-0b08a51/) joined ICIS in 2020 after 18 years at Bloomberg, where she ran the investment research business. At ICIS she plays significant role in championing the business' purpose and leading its long-term growth Strategy. Alison is passionate about diversity, equity and inclusion. She has previously represented Bloomberg on the board of the London Women's Forum (a network of senior women within the financial services industry) and is an executive sponsor of the RELX Menopause Employee Resource Group. Alison loves trying to keep fit (running, cycling and Pilates) when she gets the chance, given her second job as a taxi service to her two children. Check out all of the podcasts in the HCI Podcast Network!