Podcasts about antibodies

Immune system protein

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Best podcasts about antibodies

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Latest podcast episodes about antibodies

New Books Network
Rebecca Salazar, "antibody: poems" (McClelland & Stewart, 2025)

New Books Network

Play Episode Listen Later May 30, 2025 61:20


NBN host Hollay Ghadery speaks with acclaimed poet Rebecca Salazar about their new poetry collection, antibody: poems (McClelland & Stewart, 2025) A powerful follow-up to the Governor General's Literary Award shortlisted sulphurtongue.antibody: poems is a protest, a whisper network, a reclamation of agency, and a ritual for building a survivable world.antibody mobilizes body horror as resistance, refusing to sanitize the atrocities of sexual violence or to silence its survivors. Challenging myths of “perfect” victimhood, this collection honours the messy, rageful, queer, witchy, disabled, and kinky grief work of enduring trauma and learning to want to live. About Rebecca Salazar: Rebecca Salazar (she/they) is a queer, disabled, and racialized Latinx writer currently living on the unceded territory of the Wolastoqiyik people. Their first full-length collection sulphurtongue (McClelland & Stewart) was a finalist for the Governor General's Award for Poetry, the New Brunswick Book Awards, the Atlantic Book Awards, and the League of Canadian Poets' Pat Lowther Memorial Award. antibody is their second poetry collection. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

New Books in LGBTQ+ Studies
Rebecca Salazar, "antibody: poems" (McClelland & Stewart, 2025)

New Books in LGBTQ+ Studies

Play Episode Listen Later May 30, 2025 61:20


NBN host Hollay Ghadery speaks with acclaimed poet Rebecca Salazar about their new poetry collection, antibody: poems (McClelland & Stewart, 2025) A powerful follow-up to the Governor General's Literary Award shortlisted sulphurtongue.antibody: poems is a protest, a whisper network, a reclamation of agency, and a ritual for building a survivable world.antibody mobilizes body horror as resistance, refusing to sanitize the atrocities of sexual violence or to silence its survivors. Challenging myths of “perfect” victimhood, this collection honours the messy, rageful, queer, witchy, disabled, and kinky grief work of enduring trauma and learning to want to live. About Rebecca Salazar: Rebecca Salazar (she/they) is a queer, disabled, and racialized Latinx writer currently living on the unceded territory of the Wolastoqiyik people. Their first full-length collection sulphurtongue (McClelland & Stewart) was a finalist for the Governor General's Award for Poetry, the New Brunswick Book Awards, the Atlantic Book Awards, and the League of Canadian Poets' Pat Lowther Memorial Award. antibody is their second poetry collection. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/lgbtq-studies

New Books in Poetry
Rebecca Salazar, "antibody: poems" (McClelland & Stewart, 2025)

New Books in Poetry

Play Episode Listen Later May 30, 2025 61:20


NBN host Hollay Ghadery speaks with acclaimed poet Rebecca Salazar about their new poetry collection, antibody: poems (McClelland & Stewart, 2025) A powerful follow-up to the Governor General's Literary Award shortlisted sulphurtongue.antibody: poems is a protest, a whisper network, a reclamation of agency, and a ritual for building a survivable world.antibody mobilizes body horror as resistance, refusing to sanitize the atrocities of sexual violence or to silence its survivors. Challenging myths of “perfect” victimhood, this collection honours the messy, rageful, queer, witchy, disabled, and kinky grief work of enduring trauma and learning to want to live. About Rebecca Salazar: Rebecca Salazar (she/they) is a queer, disabled, and racialized Latinx writer currently living on the unceded territory of the Wolastoqiyik people. Their first full-length collection sulphurtongue (McClelland & Stewart) was a finalist for the Governor General's Award for Poetry, the New Brunswick Book Awards, the Atlantic Book Awards, and the League of Canadian Poets' Pat Lowther Memorial Award. antibody is their second poetry collection. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/poetry

Immune
Immune 92: Gut symbiont breaks antibody

Immune

Play Episode Listen Later May 27, 2025 80:33


Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the devastating microcephaly outcome of infection during pregnancy. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Gut bacteria induce mucosal immunodeficiency (Science) Contribution of fetal mononuclear phagocytes to Zika virus neuroinvasion (Cell) TWiV468 discusses Zika and brain slice infection model. Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

FX Medicine Podcast Central
Revolutionary insights: Autoimmune thyroid disease with Lisa Costa-Bir and Rachel Arthur

FX Medicine Podcast Central

Play Episode Listen Later May 26, 2025


In this episode , Lisa Costa-Bir is joined by leading naturopath, registered nutritionist and educator Rachel Arthur to unpack the complex landscape of autoimmune thyroid disease (AITD). Framing conditions like Hashimoto's and Graves' as systemic immune disorders - not just thyroid dysfunction - Rachel shares powerful clinical insights on diagnosis, treatment, and long-term management. With her trademark clarity and “catch cries” like “kill and spill,” Rachel breaks down the clinical significance of thyroid antibodies Thyroid Peroxidase Antibodies (TPO) and Thyroglobulin Antibodies (TgAb), Thyroid Stimulating Hormone (TSH) as a “whip,” and the self-perpetuating nature of glandular damage. She also dives deep into evidence for antioxidants like glutathione, selenium and, CoQ10, as well as discussing the value of myo-inositol, magnesium, and vitamin D - and whether there is a role for iodine supplementation in AITD. This episode is a must-listen in integrative naturopathic care for AITD - balancing nutrient timing and dose with lifestyle and dietary interventions. Essential listening for practitioners managing immune-thyroid cases in clinic. Covered in this episode: (01:01) Welcome Rachel Arthur (02:14) Autoimmune and thyroid (05:24) Thyroid antibodies (12:30) Antibody levels and severity (16:29) Root causes of elevated antibodies (22:40) Selenium (32:10) Myo-inositol (36:36) Vitamin D (50:55) Iodine (1:02:38) Diets for autoimmunity (1:09:53) Final thoughts Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/revolutionary-insights-autoimmune-thyroid-disease Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: https://login.bioceuticals.com.au ***DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***

Blood Podcast
Clonal hematopoiesis in frequent blood donors, immune microenvironment and bispecific antibody response in diffuse large B-cell lymphoma, and blinatumomab as part of early consolidation therapy in CD19-positive Ph-negative B-cell acute lymphoblastic lymph

Blood Podcast

Play Episode Listen Later May 22, 2025 20:57


In this week's episode we'll learn about how frequent blood donation affects clonal hematopoiesis in older, male blood donors; the effect of immune microenvironment on response to bispecific antibodies in diffuse large B-cell lymphoma; and the feasibility of adding blinatumomab to early consolidation therapy in CD19-positive Ph-negative B-cell acute lymphoblastic lymphoma.Featured ArticlesClonal Hematopoiesis Landscape in Frequent Blood DonorsIntegrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody responseUpfront Blinatumomab Improves MRD Clearance and Outcome in Adult Ph-negative B-lineage ALL: The GIMEMA LAL2317 Phase 2 Study

Pharma and BioTech Daily
Pharma and Biotech Daily: Pfizer's $6 Billion Bet, CRISPR Baby Success, and Bio-Rad's Antibody Discovery Platform

Pharma and BioTech Daily

Play Episode Listen Later May 21, 2025 1:10


Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world. Pfizer has made a $6 billion bet on acquiring 3SBio's PD-1/VEGF antibody, despite being a late entrant to the space. This deal comes after Pfizer's partnership with Summit Therapeutics, causing some confusion about the pharma company's overall strategy. Meanwhile, the success of a CRISPR baby has highlighted the lack of FDA-approved treatments for the 15 million children with rare diseases. Most rare conditions do not even have a treatment pipeline. Bio-Rad is redefining antibody discovery through their Pioneer™ Antibody Discovery Platform, which accelerates programs and identifies clinical-quality candidates with industry-leading timelines. FDA Commissioner Marty Makary has expressed support for psychedelic therapies for neuropsychiatric conditions, noting significant benefits for patients. The most favored nation executive order issued by Trump may face legal challenges and unintended consequences for the healthcare sector and patient access. Overall, these developments in the pharmaceutical and biotech industries highlight ongoing challenges and opportunities in drug development and treatment for rare diseases.

A New Beginning with Greg Laurie
The Holy Spirit & You, Part 2 | The Invisible Battle for Your Soul

A New Beginning with Greg Laurie

Play Episode Listen Later May 20, 2025 24:10


In our natural bodies, there are many things inside that keep us alive, although we’ve never seen them. Antibodies, clotting agents, intestinal flora, white blood cells. Now, spiritually speaking, there are invisible forces at work that want to help us and save us, although other forces want to destroy us. Today on A NEW BEGINNING, Pastor Greg Laurie points out the work of God’s Spirit acquaints us with our sin, and acquaints us with our Savior. It’s important we know how to respond. Listen on harvest.org --- Learn more and subscribe to Harvest updates at harvest.org A New Beginning is the daily half-hour program hosted by Greg Laurie, pastor of Harvest Christian Fellowship in Southern California. For over 30 years, Pastor Greg and Harvest Ministries have endeavored to know God and make Him known through media and large-scale evangelism. This podcast is supported by the generosity of our Harvest Partners.Support the show: https://harvest.org/supportSee omnystudio.com/listener for privacy information.

Harvest: Greg Laurie Audio
The Holy Spirit & You, Part 2 | The Invisible Battle for Your Soul

Harvest: Greg Laurie Audio

Play Episode Listen Later May 20, 2025 24:10


In our natural bodies, there are many things inside that keep us alive, although we’ve never seen them. Antibodies, clotting agents, intestinal flora, white blood cells. Now, spiritually speaking, there are invisible forces at work that want to help us and save us, although other forces want to destroy us. Today on A NEW BEGINNING, Pastor Greg Laurie points out the work of God’s Spirit acquaints us with our sin, and acquaints us with our Savior. It’s important we know how to respond. Listen on harvest.org --- Learn more and subscribe to Harvest updates at harvest.org A New Beginning is the daily half-hour program hosted by Greg Laurie, pastor of Harvest Christian Fellowship in Southern California. For over 30 years, Pastor Greg and Harvest Ministries have endeavored to know God and make Him known through media and large-scale evangelism. This podcast is supported by the generosity of our Harvest Partners.Support the show: https://harvest.org/supportSee omnystudio.com/listener for privacy information.

Research To Practice | Oncology Videos
Non-Hodgkin Lymphoma — An Interview with Dr Jennifer Crombie on the Use of Bispecific Antibodies

Research To Practice | Oncology Videos

Play Episode Listen Later May 20, 2025 49:55


Featuring an interview with Dr Jennifer Crombie, including the following topics: Overview of similarities and differences among CD20 x CD3 targeted bispecific antibodies for the treatment of lymphomas (0:00) Optimal integration of CD20 x CD3 bispecific antibodies into treatment algorithms for lymphomas (9:40) Case: A man in his late 60s with relapsed follicular lymphoma (FL) who received mosunetuzumab (23:52) Case: A man in his late 80s with transformed, double-hit diffuse large B-cell lymphoma (DLBCL) who received epcoritamab (28:46) Case: A woman in her early 70s with recurrent FL who received odronextamab on the ELM-1 trial (34:06) Case: A man in his early 80s with multiregimen-relapsed DLBCL who receives glofitamab (43:19) CME information and select publications

Hematologic Oncology Update
Non-Hodgkin Lymphoma — An Interview with Dr Jennifer Crombie on the Use of Bispecific Antibodies

Hematologic Oncology Update

Play Episode Listen Later May 20, 2025 49:54


Dr Jennifer Crombie from the Dana-Farber Cancer Institute in Boston, Massachusetts, reviews available and investigational CD20 x CD3 targeted bispecific antibodies for the treatment of follicular and diffuse large B-cell lymphomas. CME information and select publications here.

PeerView Heart, Lung & Blood CME/CNE/CPE Video Podcast
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Heart, Lung & Blood CME/CNE/CPE Video Podcast

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Kidney & Genitourinary Diseases CME/CNE/CPE Video Podcast
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Kidney & Genitourinary Diseases CME/CNE/CPE Video Podcast

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Kidney & Genitourinary Diseases CME/CNE/CPE Audio Podcast
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Kidney & Genitourinary Diseases CME/CNE/CPE Audio Podcast

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Heart, Lung & Blood CME/CNE/CPE Audio Podcast
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Heart, Lung & Blood CME/CNE/CPE Audio Podcast

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Clinical Pharmacology CME/CNE/CPE Video
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Clinical Pharmacology CME/CNE/CPE Video

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Gastroenterology CME/CNE/CPE Audio Podcast
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Gastroenterology CME/CNE/CPE Audio Podcast

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Gastroenterology CME/CNE/CPE Video Podcast
Sara A. Hurvitz, MD, FACP - From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors

PeerView Gastroenterology CME/CNE/CPE Video Podcast

Play Episode Listen Later May 20, 2025 85:44


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC information, and to apply for credit, please visit us at PeerView.com/KAQ865. CME/MOC credit will be available until May 27, 2026.From Innovation to Implementation: Unlocking the Full Potential of Antibody-Drug Conjugates in Solid Tumors In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., and Gilead Sciences, Inc.Disclosure information is available at the beginning of the video presentation.

Intelligent Medicine
Intelligent Medicine Radio for May 17, Part 2: "Poop Pill"

Intelligent Medicine

Play Episode Listen Later May 19, 2025 42:18


Is the “poop pill” a possible treatment for small intestinal bacterial overgrowth (SIBO)? Pro-mask, pro-lockdown, pro-vax words come back to haunt their authors as Covid response critics appointed to key HHS positions; MAHA influencer Dr. Casey Means replaces original Surgeon General nominee; Rating Trump's new vaccine czar, oncologist Vinay Prasad; Is Laetrile effective for cancer? If you're eating a diet rich in fruits and vegetables, do you still need probiotics? Researchers tap an unusual source for antivenom against deadly snakebites—a snake handler who's survived multiple poisonings.

Empowered Patient Podcast
Multispecific Antibodies and Antibody Drug Conjugates for Hard-to-Treat Cancers and Autoimmune Diseases with Dr. Paul Moore Zymeworks TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later May 12, 2025


Dr. Paul Moore, Chief Scientific Officer at Zymeworks, focuses on developing targeted therapies, particularly multispecific antibodies and antibody-drug conjugates for hard-to-treat cancers such as gynecological, thoracic, and digestive tract cancers. This approach can target multiple areas on tumor cells and immune cells, potentially overcoming tumor heterogeneity and allowing for immune system modulation. The platform allows for a plug-and-play approach, enabling the development of therapies for oncology and autoimmune diseases.  Paul explains, "So, multispecific antibodies are antibodies. Antibodies traditionally have a single target that they bind, so they're monoclonal and hit a specific target. A lot of excitement is generated for bispecific antibodies, which are engineered to bind two targets. Then with multispecifics, you are trying to broaden even further the number of targets or binding sites you've incorporated into your drug so that you can simultaneously interact with more than one target. The reason that can be important is that allows and facilitates new biology that is not possible for just a monoclonal antibody or a single antibody-targeting drug conjugate."   "Multispecifics open up the opportunity to take two targets that are on different cells, different cell populations. So, you can have a target on a tumor cell you're trying to target. Then you can have a target on an immune cell like a T cell, which you can co-engage. You can bridge a T cell to a binding domain that's on a multispecific with your second specificity, which can bind to the cell.  And what that allows you to do is bring the T cell into the environment of the tumor cell, and through that engagement, the T cell can kill the tumor cell.  So that is the foundation of a lot of excitement in bispecifics." #Zymeworks #Antibodies #MultispecificAntibodies #ADC #AntibodyDrugConjugate #Tumors #Cancer #ImmuneSystem zymeworks.com Listen to the podcast here

Empowered Patient Podcast
Multispecific Antibodies and Antibody Drug Conjugates for Hard-to-Treat Cancers and Autoimmune Diseases with Dr. Paul Moore Zymeworks

Empowered Patient Podcast

Play Episode Listen Later May 12, 2025 19:51


Dr. Paul Moore, Chief Scientific Officer at Zymeworks, focuses on developing targeted therapies, particularly multispecific antibodies and antibody-drug conjugates for hard-to-treat cancers such as gynecological, thoracic, and digestive tract cancers. This approach can target multiple areas on tumor cells and immune cells, potentially overcoming tumor heterogeneity and allowing for immune system modulation. The platform allows for a plug-and-play approach, enabling the development of therapies for oncology and autoimmune diseases.  Paul explains, "So, multispecific antibodies are antibodies. Antibodies traditionally have a single target that they bind, so they're monoclonal and hit a specific target. A lot of excitement is generated for bispecific antibodies, which are engineered to bind two targets. Then with multispecifics, you are trying to broaden even further the number of targets or binding sites you've incorporated into your drug so that you can simultaneously interact with more than one target. The reason that can be important is that allows and facilitates new biology that is not possible for just a monoclonal antibody or a single antibody-targeting drug conjugate."   "Multispecifics open up the opportunity to take two targets that are on different cells, different cell populations. So, you can have a target on a tumor cell you're trying to target. Then you can have a target on an immune cell like a T cell, which you can co-engage. You can bridge a T cell to a binding domain that's on a multispecific with your second specificity, which can bind to the cell.  And what that allows you to do is bring the T cell into the environment of the tumor cell, and through that engagement, the T cell can kill the tumor cell.  So that is the foundation of a lot of excitement in bispecifics." #Zymeworks #Antibodies #MultispecificAntibodies #ADC #AntibodyDrugConjugate #Tumors #Cancer #ImmuneSystem zymeworks.com Download the transcript here

Pharma and BioTech Daily
Pharma and Biotech Daily: AI Integration, Sanofi Cuts Ties, FDA Delays, and Trump's Drug Pricing Plan

Pharma and BioTech Daily

Play Episode Listen Later May 12, 2025 0:45


Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world. The FDA is planning to fully integrate AI into their decision-making process by June 30, with individual centers starting the rollout immediately. Sanofi has cut off its antibody partner, leading to an 80% reduction in headcount at IgM Biosciences. The FDA has faced delays, including missing review dates for GSK's Nucala. President Trump is expected to unveil a drug pricing plan on Monday that has been criticized by big pharma and patient groups. Lotte Biologics offers end-to-end services for ADC manufacturing in Syracuse, NY. Rallybio, Insitro, Shape, and Vor have all downsized their workforces.

Clinical Chemistry Podcast
Pediatric vaccine-induced antibody thresholds: Rethinking pre-immunosuppression serologic testing and revaccination implications

Clinical Chemistry Podcast

Play Episode Listen Later May 8, 2025 11:21


The Fellow on Call
Episode 135: VTE Series - Management of Antiphospholipid Antibody Syndrome

The Fellow on Call

Play Episode Listen Later May 7, 2025


This week, we round out our discussion we started in our prior episode on APLS, this time focusing on management. Stick around until the end to hear Dan and Vivek battle it out about the optimal time to recommend APLS testing for your patients!If you have not done so already, we highly recommend you check out episode 134 (diagnosis of APLS) prior to jumping into this one!Episode contents:- What is the best choice of anticoagulant? - Is a higher INR better for warfarin? - Are DOACs acceptable options? - What is the optimal time to send APLS testing? **** Get paid to participate in market research surveys: https://affiliatepanel.members-only.online/FOC_24?utm_campaign=FOC&utm_source=email&utm_medium=email** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast
Suzanne Lentzsch, MD, PhD - Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast

Play Episode Listen Later May 6, 2025 38:33


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/MBK865. CME/AAPA credit will be available until April 20, 2026.Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and HealthTree Foundation for Multiple Myeloma. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies) and Sanofi.Disclosure information is available at the beginning of the video presentation.

PeerView Oncology & Hematology CME/CNE/CPE Video Podcast
Suzanne Lentzsch, MD, PhD - Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies

PeerView Oncology & Hematology CME/CNE/CPE Video Podcast

Play Episode Listen Later May 6, 2025 38:33


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/MBK865. CME/AAPA credit will be available until April 20, 2026.Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and HealthTree Foundation for Multiple Myeloma. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies) and Sanofi.Disclosure information is available at the beginning of the video presentation.

PeerView Oncology & Hematology CME/CNE/CPE Audio Podcast
Suzanne Lentzsch, MD, PhD - Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies

PeerView Oncology & Hematology CME/CNE/CPE Audio Podcast

Play Episode Listen Later May 6, 2025 38:33


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/MBK865. CME/AAPA credit will be available until April 20, 2026.Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and HealthTree Foundation for Multiple Myeloma. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies) and Sanofi.Disclosure information is available at the beginning of the video presentation.

PeerView Clinical Pharmacology CME/CNE/CPE Video
Suzanne Lentzsch, MD, PhD - Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies

PeerView Clinical Pharmacology CME/CNE/CPE Video

Play Episode Listen Later May 6, 2025 38:33


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/MBK865. CME/AAPA credit will be available until April 20, 2026.Starting With a Frontline “Four” in Multiple Myeloma: Case-Based Guidance for Achieving Durable Remissions With Innovative CD38 Antibody Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and HealthTree Foundation for Multiple Myeloma. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies) and Sanofi.Disclosure information is available at the beginning of the video presentation.

Ducks Unlimited Podcast
Ep. 673 - Essential Puppy Care: Vaccinations, Nutrition, and Training Tips

Ducks Unlimited Podcast

Play Episode Listen Later May 1, 2025 44:44


In this episode of the Ducks Unlimited Podcast, we're joined by Dr. RuthAnn Lobos of Purina. We dive deep into puppy health, discussing essential vaccines, building immunity, the science behind proper nutrition, and why it all matters for your duck dog. Plus, Dr. Lobos shares valuable socialization tips to help your puppy grow into a confident hunting companion.Listen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.org

Save My Thyroid
Real Answers to Your Thyroid Problems ( Part 2 )

Save My Thyroid

Play Episode Listen Later May 1, 2025 45:26


If you've ever Googled your way into confusion, felt unsure about treatments, or just wished someone would break it all down in plain language—this QA episode is for you.Dr. Eric answers listener questions with clarity and care, breaking down complex topics like postpartum hyperthyroidism, iodine contrast risks in CT scans, and the role of inulin in gut health. He also shares insights on natural remedies like bugleweed and castor oil packs, managing hormone therapy, and addressing elevated homocysteine levels. Plus why gut health, genetics, and lifestyle all play a part. It's a clear, helpful look at the thyroid questions so many are asking.Tune in now for insights that can help you feel more in control of your thyroid journey.Episode Timeline: 0:00 – Episode introduction 0:16– Overview of thyroid and autoimmune conditions0:30 - Do CT Scans with Contrast Harm Your Thyroid?1:41 - Postpartum Hyper to Hypothyroid Flop4:10 - Is Inulin Safe for Hashimoto's?5:42 - Bugleweed, Antibodies and the Hyper Cycle8:16 - Tackling High Homocysteine Levels10:12 - Can Genes Flip You from Graves to Hypo?11:48 - Is Quercetin Safe with Desiccated Thyroid?13:28 - Natural Ways to Handle Hyperthyroidism14:39 - Thoughts on Rife Frequencies and Healing20:31 - Short Break21:21 - Always Low T3 Despite Meds22:34 - Does an Uptake Scan Change Anything?23:06 - High Antibodies but Labs Look Good23:41 - Treating Hyperthyroid While Breastfeeding25:42 - Does Thyroxine Fix Hashimoto's or Just Mask It?26:39 - Subclinical Hyper or Something Else28:57- Can an Ultrasound Trigger Seizures?29:51 - HRT and Possible Thyroid Flare31:41 - What's Optimal Free T3 and Reverse T3?32:57 - Can You Fully Reverse Subclinical Hyper?33:38 - Lab Variability and Tracking Bugleweed Effects36:51 - Healing Hyperthyroidism Without Meds37:41 - Hoping to Get Off Levothyroxine Naturally39:47 - Can You Take Bugleweed While on Meds?40:37 - Is Hydrogen Water Safe with Thyroid Meds?41:24 - Can You Take T3 on Its Own?43:08 - Wrapping Up the Q&A43:31 - Where to Ask More Questions43:49 - Submit Your Questions for Future Episodes44:00 - Podcast OutroMentioned In This Episode: Dr. Eric' BooksNatural Treatment Solutions for Hyperthyroidism and Graves' Disease Amazon.com: The Hyperthyroid Healing Diet: Reverse Hyperthyroidism and Graves' Disease and Save Your Thyroid Through Diet and Lifestyle Changes Hashimoto's Triggers: Eliminate Your Thyroid Symptoms By Finding And Removing Your Specific Autoimmune TriggersDr. Eric's Podcast: How To Lower Thyroid AntibodiesHow To Lower Thyroid Antibodies Part 1Saving Your Thyroid Through Rad Do You Want Help Saving Your Thyroid? Access hundreds of free articles at www.NaturalEndocrineSolutions.com Visit Dr. Eric's YouTube channel at www.youtube.com/c/NaturalThyroidDoctor/ To work with Dr. Eric, visit https://savemythyroid.com/work-with-dr-eric/

Find your model health!
#374 Hypothyroid prevalence, Thyroid antibodies, TSH misconceptions, Hypopituitarism with Carol Petersen.

Find your model health!

Play Episode Listen Later Apr 29, 2025 66:14


The highly intelligent Carol Petersen is back to discuss Thyroid health but first...We apologize for some of the breaks in this conversation, we are both having issues with our WIFI but hopefully you still find this helpful. The podcast version has most of the breaks taken out, so will be clearer to listen to. Thank you for understanding. :) But this really is a fantastic very considered conversation around Thyroid health and hypothyroidism with Carol.

Research To Practice | Oncology Videos
Oncology Nursing Edition: Antibody-Drug Conjugates for Breast Cancer and Lung Cancer — Proceedings from the 2025 Annual ONS Congress

Research To Practice | Oncology Videos

Play Episode Listen Later Apr 26, 2025 93:03


Featuring perspectives from Ms Marianne J Davies, Dr Edward B Garon, Ms Marissa Marti-Smith and Dr Tiffany A Traina, including the following topics: Introduction (0:00) Overview of Antibody-Drug Conjugates (ADCs) (4:40) Trastuzumab Deruxtecan (T-DXd) in Patients with HER2-Positive Metastatic Breast Cancer (mBC) with and without Brain Metastases (12:40) Role of ADCs for Patients with ER-Positive mBC (35:09) T-DXd in Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC) with HER2 Alterations (52:20) Emerging Role of ADCs for Patients with Progressive EGFR-Mutant NSCLC (1:12:20) NCPD information and select publications

Breast Cancer Update
Oncology Nursing Edition: Antibody-Drug Conjugates for Breast Cancer and Lung Cancer — Proceedings from the 2025 Annual ONS Congress

Breast Cancer Update

Play Episode Listen Later Apr 26, 2025 93:02


Dr Edward B Garon, Dr Tiffany A Traina, and nurse practitioners Ms Marianne J Davies and Ms Marissa Marti-Smith discuss the role of antibody-drug conjugates in the care of patients with breast and lung cancer and strategies to mitigate and manage treatment-emergent adverse events. NCPD information and select publications here.

Lung Cancer Update
Oncology Nursing Edition: Antibody-Drug Conjugates for Breast Cancer and Lung Cancer — Proceedings from the 2025 Annual ONS Congress

Lung Cancer Update

Play Episode Listen Later Apr 26, 2025 93:02


Dr Edward B Garon, Dr Tiffany A Traina, and nurse practitioners Ms Marianne J Davies and Ms Marissa Marti-Smith discuss the role of antibody-drug conjugates in the care of patients with breast and lung cancer and strategies to mitigate and manage treatment-emergent adverse events. NCPD information and select publications here.

Stocks To Watch
Episode 580: How ImmunoPrecise Antibodies ($IPA) Uses AI to Transform Antibody-Based Drug Discovery

Stocks To Watch

Play Episode Listen Later Apr 25, 2025 17:36


What happens when decades of lab expertise meet cutting-edge AI? In this interview, Dr. Jennifer Bath, President and CEO of ImmunoPrecise Antibodies Ltd. (NASDAQ: IPA), talks about how her team is using advanced science and artificial intelligence to develop safer, faster, and more effective antibody-based medicines. With over 3,000 antibody discovery programs completed, they are transforming the future of drug discovery—cutting time, costs, and risks in the development process. Discover how decades of hands-on lab experience and innovative AI tools are helping identify the best drug candidates faster than ever before.Learn more about ImmunoPrecise Antibodies: https://www.ipatherapeutics.com/Watch the full YouTube interview here: https://youtu.be/mE9mDa7uGTsAnd follow us to stay updated: https://www.youtube.com/@GlobalOneMedia?sub_confirmation=1

Cancer Buzz
Targeting Progress: Patient Perspective on Antibody-Drug Conjugates in Gynecologic Cancer Care

Cancer Buzz

Play Episode Listen Later Apr 24, 2025 11:12


Antibody-drug conjugates (ADCs) are novel therapeutic agents designed to target specific tumor markers with potent anticancer drugs. The Association of Cancer Care Centers (ACCC) is dedicated to providing up-to-date information on ADC treatment management. In this episode, CANCER BUZZ speaks with Nancy Mallett, a patient advocate, to discuss the patient's perspective and experience receiving treatment for gynecologic cancers, particularly with ADCs such as mirvetuximab soravtansine-gynx. “[Providers] giving me the information and allowing us to decide together, instead of just telling me, makes me feel more cared about and that I'm not just a number, I'm a person. They care about what I think, and look at my life and what it can do for me.” – Nancy Mallett   Nancy Mallett Patient Advocate   Resources:  FDA Approval Summary: Mirvetuximab soravtansine-gynx for FRα-positive, Platinum-Resistant Ovarian Cancer - https://bit.ly/4is00nD  Society of Gynecologic Oncology (SGO): Gynecologic Cancer Resources for Patients and Their Families - https://bit.ly/4jpYaoP  ASCO: Antibody-Drug Conjugates in Gynecologic Cancer - https://bit.ly/42GP5k8  Society of Gynecologic Oncology Journal Club: The ABCs of ADCs (Antibody drug Conjugates) - https://bit.ly/42U2962  Antibody-Drug Conjugates in Gynecologic Cancers - https://bit.ly/4cLYECZ    Funder Statement  This program is supported by AbbVie.   

The Fellow on Call
Episode 134: VTE Series - Diagnosis of Antiphospholipid Antibody Syndrome

The Fellow on Call

Play Episode Listen Later Apr 23, 2025


This week, we continue our series focusing on venous thromboembolism. In this episode, we begin our discussion of antiphospholipid syndrome.Episode contents:- What is "antiphospholipid antibody syndrome"?- How do we make this diagnosis?- What is the optimal time to test for these antibodies? **** Get paid to participate in market research surveys: https://affiliatepanel.members-only.online/FOC_24?utm_campaign=FOC&utm_source=email&utm_medium=email** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast

Empowered Patient Podcast
AI-Powered Antibody Drug Discovery for Obesity and Cardiometabolic Diseases with Martin Brenner iBio TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later Apr 21, 2025


Martin Brenner, CEO and Chief Scientific Officer of iBio, is focused on the untapped potential of therapeutic antibodies for obesity and cardiometabolic diseases. Leveraging AI and machine learning, iBio is streamlining the antibody discovery and optimization process and addressing the need for more complex antibody mechanisms of action. Their lead candidate, iBio 600, is an anti-myostatin antibody designed to address the side effects of muscle mass and bone density loss associated with current GLP-1 therapies. Martin explains, "We can separate this into multiple areas. First of all, there's a predictive model that suggests that there are 5,000 different targets related to disease out there. So, there are 5,000 different possibilities to make medicines. All of the currently approved antibodies target only 92 targets. Even worse, 40% of approved antibodies only target about 10. So you can imagine there's a huge untapped potential of novel targets for which antibodies could be used. The problem is that the technologies must keep up with this to open that novel target space. That is problem number one." "So, as you know, AI has gotten a little bit of a bad reputation over the last few years, and there was a huge hype about this, and I want to be very clear about this. It takes more than 10,000 steps to make a medicine. At iBio, we enable three of these steps with generative AI. So, that does not make us an AI company. That does not make our molecules AI drugs. What it does is it actually makes it possible for us to create medicines that we couldn't do before. So, the way we use AI at iBio is multiplefold. First, we start our discovery process with the epitope steering engine. You have to imagine that drug targets are massive proteins, and only very small regions on these proteins have a biological function. So you want to get your antibody exactly to those regions that cause a biological function."  #iBio #DrugDiscovery #MedAI #Obesity #GLP1 #CardioMetabolicDiseases #Antibodies #AntibodyTherapies #Myostatin iBioinc.com Listen to the podcast here

Empowered Patient Podcast
AI-Powered Antibody Drug Discovery for Obesity and Cardiometabolic Diseases with Martin Brenner iBio

Empowered Patient Podcast

Play Episode Listen Later Apr 21, 2025 21:56


Martin Brenner, CEO and Chief Scientific Officer of iBio, is focused on the untapped potential of therapeutic antibodies for obesity and cardiometabolic diseases. Leveraging AI and machine learning, iBio is streamlining the antibody discovery and optimization process and addressing the need for more complex antibody mechanisms of action. Their lead candidate, iBio 600, is an anti-myostatin antibody designed to address the side effects of muscle mass and bone density loss associated with current GLP-1 therapies. Martin explains, "We can separate this into multiple areas. First of all, there's a predictive model that suggests that there are 5,000 different targets related to disease out there. So, there are 5,000 different possibilities to make medicines. All of the currently approved antibodies target only 92 targets. Even worse, 40% of approved antibodies only target about 10. So you can imagine there's a huge untapped potential of novel targets for which antibodies could be used. The problem is that the technologies must keep up with this to open that novel target space. That is problem number one." "So, as you know, AI has gotten a little bit of a bad reputation over the last few years, and there was a huge hype about this, and I want to be very clear about this. It takes more than 10,000 steps to make a medicine. At iBio, we enable three of these steps with generative AI. So, that does not make us an AI company. That does not make our molecules AI drugs. What it does is it actually makes it possible for us to create medicines that we couldn't do before. So, the way we use AI at iBio is multiplefold. First, we start our discovery process with the epitope steering engine. You have to imagine that drug targets are massive proteins, and only very small regions on these proteins have a biological function. So you want to get your antibody exactly to those regions that cause a biological function."  #iBio #DrugDiscovery #MedAI #Obesity #GLP1 #CardioMetabolicDiseases #Antibodies #AntibodyTherapies #Myostatin iBioinc.com Download the transcript here

The Asianometry Podcast
The Chinese Hamster Revolutionized Medicine

The Asianometry Podcast

Play Episode Listen Later Apr 20, 2025


What was the world's top selling drug in 2023? Maybe the magic weight losing drug semaglutide, better known as Ozempic? Or the COVID vaccine perchance? Nope. 2023's top selling drug was an antibody, Keytruda, with about $25 billion in sales. $27 billion projected for 2024. In fact, five of the top ten best selling drugs in 2023 were antibodies. Antibody therapies revolutionized medicine. We have long known they can. The problem has always been how to make them the right way and at industrial scale. Today it is done with the help of a hamster. Or rather its cells. In this video, the incredible story of the hamster that revolutionized medicine. This is one of my favorite videos of the year.

The Asianometry Podcast
The Chinese Hamster Revolutionized Medicine

The Asianometry Podcast

Play Episode Listen Later Apr 20, 2025


What was the world's top selling drug in 2023? Maybe the magic weight losing drug semaglutide, better known as Ozempic? Or the COVID vaccine perchance? Nope. 2023's top selling drug was an antibody, Keytruda, with about $25 billion in sales. $27 billion projected for 2024. In fact, five of the top ten best selling drugs in 2023 were antibodies. Antibody therapies revolutionized medicine. We have long known they can. The problem has always been how to make them the right way and at industrial scale. Today it is done with the help of a hamster. Or rather its cells. In this video, the incredible story of the hamster that revolutionized medicine. This is one of my favorite videos of the year.

Research To Practice | Oncology Videos
Oncology Nursing Update Special 2-Part Edition: Bispecific Antibodies in Lymphoma — Part 2

Research To Practice | Oncology Videos

Play Episode Listen Later Apr 18, 2025 58:21


Featuring an interview with Ms Amy Goodrich, including the following topics: Presentation and management of follicular lymphoma (FL) (0:00) Case: A woman in her late 70s with heavily pretreated disease experiences complete response to mosunetuzumab (24:41) Case: A man in his early 60s with extensive diffuse large B-cell lymphoma and short response to CAR-T is successfully bridged to allogeneic transplant with glofitamab (30:15) Case: A man in his late 50s with transformed FL has limited treatment options due to lack of social support (45:51) Effects of bispecific antibodies in follicular and diffuse large B-cell lymphoma (52:53) NCPD information and select publications

Hematologic Oncology Update
Oncology Nursing Update Special 2-Part Edition: Bispecific Antibodies in Lymphoma — Part 2

Hematologic Oncology Update

Play Episode Listen Later Apr 18, 2025 58:21


Nurse practitioner Ms Amy Goodrich from The Sidney Kimmel Comprehensive Care Center in Baltimore, Maryland, presents cases from her practice illustrating the efficacy and safety of bispecific antibodies for non-Hodkin lymphoma. NCPD information and select publications here.

CME in Minutes: Education in Primary Care
Aditya Bardia, MD / Sara Hurvitz, MD - Making a World of Difference for Patients With HER2-Low and -Ultralow Advanced Breast Cancer: Practical Strategies to Integrate Antibody-Drug Conjugates in Special Populations

CME in Minutes: Education in Primary Care

Play Episode Listen Later Apr 16, 2025 30:09


Please visit answersincme.com/860/95483855-replay3 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, experts in oncology discuss practical strategies for integrating antibody-drug conjugates in special populations with HER2-low advanced breast cancer and essential adverse event management approaches. Upon completion of this activity, participants should be better able to: Review guideline-concordant approaches to individualize treatment selection for patients with HER2-low and -ultralow advanced breast cancer; and Outline evidence-based strategies to enhance the management of patients with HER2-low and -ultralow advanced breast cancer.

North American Ag Spotlight
Ostrich Antibodies & Avian Flu: Is Science Being Ignored?

North American Ag Spotlight

Play Episode Listen Later Apr 2, 2025 47:28 Transcription Available


Season 5: Episode 207In this North American Ag Spotlight podcast episode, host Chrissy Wozniak interviews Katie Pasitney from Universal Ostrich, a family-owned ostrich farm in British Columbia, Canada. The farm, which has been raising ostriches for 35 years, is facing a crisis due to a government order to cull over 400 ostriches amid an avian flu outbreak, despite most birds showing resistance and antibodies to the virus.Katie explains that the farm has shifted focus in recent years to groundbreaking antibody research in collaboration with Kyoto Prefectural University in Japan. They inoculate ostriches with antigens to produce robust antibodies in their egg yolks, which could be used to create nutraceuticals like lozenges and nasal sprays to boost human immunity against diseases, including COVID-19 variants. This research has shown promising results, with one ostrich egg containing antibodies equivalent to 100 chicken eggs or the blood of 800 rabbits, offering a humane and efficient alternative.The crisis began in December 2024 when the farm noticed symptoms similar to a 2020 pseudomonas bacteria outbreak, initially linked to migratory mallard ducks. However, the Canadian Food Inspection Agency (CFIA), acting on an anonymous tip, tested two deceased ostriches and confirmed H5N1 avian influenza using PCR tests, rejecting the farm's request to test healthy birds or conduct a broader study. Despite the farm's isolation and the ostriches' apparent herd immunity—evidenced by 76 days without symptomatic deaths post-quarantine—the CFIA ordered the entire flock's destruction, citing trading partner policies influenced by the World Health Organization and the UN.Katie highlights the farm's struggle against what she calls a “stamping out” policy that prioritizes mass culling over preserving natural immunity, potentially benefiting Big Pharma by eliminating alternatives to vaccines. The CFIA has threatened a $250,000 fine or jail time if the farm tests its own animals, and even probed for intellectual property during a 5.5-hour meeting, despite having already signed a kill order on December 30, 2024. The family faces a deadline to kill and bury the ostriches themselves or lose compensation if a third-party contractor intervenes.With a judicial review scheduled for mid-April, the farm is fighting legally to save their ostriches and research, having raised over $60,000 for legal fees but facing $100,000 more in outstanding costs. Katie pleads for public support, emphasizing the global implications for agriculture and natural immunity, and directs listeners to saveourostiches.com for updates and donations.Chrissy underscores the story's urgency, calling for action against government overreach and the preservation of this potentially revolutionary science, urging listeners to share the episode and support the cause. Learn more about this cause at https://bcrising.ca/save-our-ostriches/ and give to the cause at https://www.givesendgo.com/save-our-ostriches or https://www.gofundme.com/f/help-ostrich-farmers-fight-to-save-herd-from-avian-flu?attribution_id=sl%3A80e09934-7413-429b-acfb-2f7015cc19d3&lang=en_CA#ostrich #farming #agricultureDon't just thank a farmer, pray for one toSend us a textAgritechnica in Hannover, Germany is held every other year, this year long-time tech writer & ag journalist Willie Vogt has put together for ag enthusiasts! The Agritechnica tour includes three days at the huge equipment and farm technology event. Learn more - https://agtoursusa.com/agritechnica.htmlSubscribe to North American Ag at https://northamericanag.com

This Week in Virology
TWiV 1203: What's old is flu again

This Week in Virology

Play Episode Listen Later Mar 23, 2025 116:57


TWiV explains why RFK Jr.'s proposal to let H5N1 infections in birds ‘rip' is a bad idea, phase 1/2 trial of combined influenza/COVID mRNA vaccines, and how your first influenza virus exposure shapes the B cell response to influenza vaccination 50 years later. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 RFK Jr. says let H5N1 rip through flocks (NY Times) Combined flu/COVID mRNA vaccine (Nat Comm) Rare syndrome after COVID vaccination (NY Times, medRxiv) Imprinting lasts 50 years (Immunity) Imprinting protects against H5N1 and H7N9 (Science) Letters read on TWiV 1203 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Node-Focal Plane Image Competition Rich – Periodic cooking of eggs Vincent – The use of placebo controls in clinical trials Listener Picks Anne – Everything is Tuberculosis by John Green Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

#moldfinders: RADIO
186: Pediatric Mold Expert: Autism is a Brain Allergy! Binders Don't Work for Kids! 50% of Autism and PANS is Mold Toxicity... Dr. Pejman Katiraei

#moldfinders: RADIO

Play Episode Listen Later Mar 19, 2025 76:18


I'm really excited to introduce today's guest, Dr. Pejman Katiraei!Mold exposure can have a profound impact on children's health, especially for kids with Autism Spectrum Disorder (ASD) and Pediatric Acute Neuropsychiatric Syndrome (PANS). In this episode, Dr. Pejman Katiraei shares his in-depth mold protocol designed specifically for children dealing with these complex conditions.

Public Health On Call
868 - COVID-19 Convalescent Plasma: From Emergency to Everyday

Public Health On Call

Play Episode Listen Later Mar 13, 2025 12:22


About this episode: In the early days of the COVID-19 pandemic when there were no vaccines or treatments, convalescent plasma—antibody-containing blood from people who recovered from COVID—saved countless lives through Emergency Use Authorization. In this episode: special guest host Thomas Locke of MMI Monthly: From Bench To Breakthrough discusses the evolution of CCP therapy, from emergency use during the pandemic to now, nearly five years later, crossing the finish line with recent FDA approval as a potential treatment for immunocompromised patients. Guest: David Sullivan is a professor in Molecular Microbiology and Immunology and a researcher at the Johns Hopkins Malaria Research Institute. Host: Thomas Locke is the host of MMI Monthly: From Bench to Breakthrough and Malaria Minute,  podcasts from the department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health. Show links and related content: Bloomberg School Researchers Support First Blood Center to Receive Full FDA Approval to Provide Convalescent Plasma for Patients Who Are Immunocompromised—Johns Hopkins Bloomberg School of Public Health Convalescent Plasma Offers ‘Blueprint' For Future Pandemics—The Hub How a Boy's Blood Stopped an Outbreak—The Wall Street Journal (Opinion) Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌JohnsHopkinsSPH on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.