Podcasts about dairy science

In the Real Science Exchange Legacy Series, we celebrate the pioneers who have shaped the dairy industry. In this episode, we honor Dr. Don Beitz, a distinguished professor at Iowa State University. At the 2025 ADSA Annual Meeting, a symposium was held titled “Donald C. Beitz Recognition Symposium: 50-Plus Years of Dairy Science Research.” The guests on this episode, all former graduate students of Dr. Beitz, were speakers at the event. Join us as we explore Dr. Beitz's contributions and enduring impact on our industry. Panelists introduce themselves and how they met Dr. Beitz. Tricky MS and PhD exam questions are also shared. Panelists emphasize Dr. Beitz's love for biochemistry, teaching, and collaboration. (1:17)Dr. Beitz shares about his early life, academic career, and family. (11:45)Dr. Goff's symposium presentation focused on Dr. Beitz and colleagues' contribution to our understanding of transition cow hypocalcemia. He talks about studies on low calcium diets, investigating the metabolic pathways of vitamin D, and low phosphorus diets. Dr. Beitz also studied the impact of vitamin D on meat tenderness. (22:37)Dr. Nelson's presentation detailed the advances in understanding bovine immunology from the work of Don Beitz and his colleagues. From the milk fever vitamin D research, it was also discovered that vitamin D had an impact on the immune system, which led to further work with vitamin A and immunity as well. Dr. Beitz also had students investigate calf growth rate influence on immune system development as well as Johne's disease. (27:22)Dr. Drackley focused on Dr. Beitz's work in understanding fatty liver and ketosis. The transition period was of interest to Dr. Beitz, which is reflected not only in his work in hypocalcemia, but also the lipid and carbohydrate metabolism of ketosis. Dr. Beitz and his colleague, Dr. Young, developed a successful ketosis model using a slight feed restriction and supplementing a ketone body precursor, which was used to investigate ketosis and fatty liver. (30:25)Dr. VandeHaar spoke about Dr. Beitz's passion for research and teaching in dairy science, biochemistry, and life. He emphasized the depth and breadth of Dr. Beitz's work and teaching. He shared that Dr. Beitz has served as major professor for around 107 graduate students and has taught biochemistry to over 16,000 students. (35:02)The panelists share stories about Dr. Beitz's humility, care and support for students, and the many different professional societies he has been involved in over his career. (38:39)Panelists share their take-home thoughts. (42:56)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this episode of The Dairy Nutrition Blackbelt Podcast, Dr. Alice Brandao from Texas A&M University explores how insulin resistance, feed additives, and energy sources influence dairy cattle health. She shares insights from her work in Brazil, where challenging conditions call for adaptive nutritional strategies. Learn what impacts immune modulation and metabolic responses in transition cows. Listen now on all major platforms!"Feed additives are great tools, but they are not silver bullets or magic wands."Meet the guest: Dr. Alice Brandao is an Instructional Assistant Professor at Texas A&M University's Department of Animal Science. With a background in veterinary medicine from Brazil, she pursued her M.S. in Dairy Science and Ph.D. in Animal Sciences.Liked this one? Don't stop now — Here's what we think you'll love!What will you learn: (00:00) Highlight(01:07) Introduction(06:44) Insulin resistance factors(08:49) Chromium supplementation effects(09:42) Non-starch energy sources(11:22) Immune modulation strategies(13:49) Feed additive challenges(16:42) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Adisseo* Fortiva* Priority IAC- Kemin- Virtus Nutrition

In this episode of The Dairy Podcast Show, Steve Martin from DNMCmilk discusses the evolution and optimization of distillers grains in dairy cow diets. Drawing from decades of experience, he explains the nutritional and economic factors driving ingredient selection, the balance of fatty and amino acids, and strategies for feed cost efficiency. Listen now on all major platforms!"Understanding how distillers grains are produced is essential because each processing pathway creates a different nutritional profile for dairy cattle diets."Meet the guest: Steve Martin earned his B.S. in Animal and Dairy Science from Auburn University and his M.S. in Animal Nutrition from Texas A&M University. With more than 30 years in the industry, he has served as a dairy nutritionist, consultant, and founder of DNMCmilk, providing expertise in feed formulation, milk economics, and heifer nutrition. Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:40) Introduction(07:55) History of distillers grains(11:10) Feeding management rules(16:10) Fat and protein balance(21:25) Diet optimization(26:40) Dairy risk and innovation(29:20) Final three questionsThe Dairy Podcast Show is trusted and supported by innovative companies like:* Lallemand* Adisseo* Afimilk* Evonik* Priority IAC- Protekta- AHV- Natural Biologics- Berg + Schmidt- SmaXtec- dsm-firmenich- ICC

In this episode of The Milk Check, Ted Jacoby III welcomes Lloyd Metzger and TJ Jacoby of Valley Queen Cheese Company for a deep dive into the science, functionality and future of dairy proteins. The conversation starts at the molecular level – the difference between casein and whey – and builds toward the real-world implications for product developers, processors and nutrition brands. We cover: Why casein is built to carry calcium (and whey isn’t) How heat and pH change protein behavior Fast versus slow digestion and why both matter The role of whey protein in muscle maintenance, aging and GLP-1 nutrition What pro cream really is and why its value may be underestimated Why cellular agriculture is more niche than threat If you work in dairy, food formulation or nutrition, this is a protein conversation worth digesting. Got questions? We'd love to hear them. Submit below, and we might answer it on the show. Ask The Milk Check TMC-Intro-final[00:00:00]Ted Jacoby III: Hi everybody, and thank you for joining us today for this very special recording of the Milk Check Podcast. Today, our topic is: what is the future of dairy proteins? And we have two very special guests. The first is Lloyd Metzger, VP of Quality and Technical Services for Valley Queen Cheese Company, and formerly Professor of Dairy Science at South Dakota State University. And the second, particularly special to me, is my son TJ Jacoby, Whey Technologist for Valley Queen. A South Dakota State graduate. Someone who has been interested in dairy proteins since his first biology class in high school. Guys, thank you for joining us today and welcome to The Milk Check. Lloyd Metzger: Glad to be here. TJ Jacoby: Good to be on, Dad. Ted Jacoby III: It’s December 18th, 2025. Milk production in the US is up 4%. Milk production in Europe is up something similar. Milk production in New Zealand is up. Milk production in Argentina is up. We are definitely in an [00:01:00] environment today where the supply of milk and dairy is overwhelming demand, at least for the moment. Cheese prices are near historical lows. Butter prices are near historical lows. Nonfat milk, skim milk powder prices are on the low end of the range. This market is a market that feels heavy, and I think most people out there would say, it almost feels like even though we’re at lows, we may actually go lower before we go higher. And yet, on the other hand, there are whey proteins, Josh, if I’m not mistaken, whey proteins just hit historical highs. Josh White: Maybe the highest prices we’ve ever seen for whey protein isolate and WPC 80. Ted Jacoby III: So, we have an environment where the demand on the protein side is extremely strong, and the trends on protein consumption are extremely strong and really feel like they’re gonna be around for quite some time. We’ve got baby boomers retiring and whether it’s because of GLP-1s or it’s just a general knowledge and understanding of what human nutritional needs are as people age, they know that they need more protein in their [00:02:00] diet. So, it begs the question: what is going on with dairy proteins and whey proteins and how is this going to evolve in such a unique market where demand is so strong for protein right now? And so, I’m gonna ask the question first. What’s the difference at a molecular level between whey proteins and milk proteins? Because when we’re in an environment like we are now, where you’ve got the demand really, really high, you also have a market that’s gonna start looking for alternatives, simply because prices are so high. What is the difference between milk proteins in general and whey protein specifically? Lloyd Metzger: It’s important to talk about from a functional perspective how the proteins are different. I’m sure we’ll get into the nutritional differences between those proteins as well. It’s important to understand what’s driving those differences in functional characteristics. And it’s really all about calcium. The casein system is designed to carry calcium. The whey protein system is not designed to carry calcium. That differentiates the two groups of [00:03:00] proteins and makes their properties very different. TJ Jacoby: I’ll explain it like this. Milk proteins, there’s two classes of proteins, right? There’s casein and then there’s whey. The casein is used to make cheese, and then the whey protein is what comes off. So, the whey protein is everything that is not used to make cheese. So, the reason why casein proteins works so well for cheese because those proteins like to fall together in these spheres, they like to stick to one another. They like to stick to one another ’cause they have certain groups that latch onto the calcium and then they bridge with phosphate. When they do, they have multiple proteins, different types of casein proteins that bridge together with phosphate and then based on their repulsion forces, they stick together. Calcium and phosphates really help it stick when we make cheese. The outside of that casein, micelle, that ball, when we make cheese, that outside is stripped off, it becomes hydrophobic, and that causes those spheres to stick together. That’s a huge functional property of casein. Whey [00:04:00] protein is the opposite. Whey protein is really hydrophillic. It’s very polar. So, they like to float around in solution and stay floating around in solution. And they don’t like casein. It likes to stay separate from casein. And so, when you make cheese, it readily is released into the whey stream because it likes to stick with the water. In the same way, those kind of stick together with these sulfur groups. But when you heat it up, they unfold. And when they unfold, now there’s certain reactions that can take place. So, those are the two major differences between casein and whey. Lloyd, what did I miss? Lloyd Metzger: I would try to simplify it a little bit. The difference between casein and whey protein is casein is what’s trapped when we make cheese. And whey protein is the soluble protein that’s left over in the water phase of cheese. Cheese making is a dehydration process. We concentrate the fat and protein that’s in milk, the casein version of protein in milk. But you gotta look at the properties of those two [00:05:00] systems and the groups of protein. So, the casein protein is actually really stable to heat, but it is not stable to pH. So, casein will always coagulate at low pH. So, you lower the pH of milk, you get a yogurt-like product. That’s all the casein that’s coming out of the system. Whey proteins don’t mind a low pH, and they’ll stay soluble at a wide range of pH. But now, when you get to temperature, the complete opposite happens. Casein can handle super high temperatures and be very stable. Whey proteins can not handle high temperature at all, they start to gel. I think it’s important to look at the two different groups. Now you get into the functional differences between those two and the very different properties you have between those. Lloyd Metzger: That’s why you get all these products that are very different from each other. Why cheese is so much different than whey protein. And then you have these dairy products that are a combination that have the two together. So like when we make yogurt, we end up with the two products together and get this property that’s partway in between the two proteins. Ted Jacoby III: [00:06:00] Based on what you’re describing, when we’re talking about milk proteins, MPC 80, for example, there’s a higher level of calcium, I take it in milk proteins than compared to whey proteins. Is that true? Lloyd Metzger: Absolutely, but let’s remind everybody: milk protein is both casein and whey protein together at the normal ratio that’s in milk. So, of the protein, 80% is casein, 20% is whey protein. So, when you say milk protein, you’re actually meaning 80% casein and 20% whey protein. Now, when we talk about cheese or casein, we’re basically a hundred percent casein and 0% whey protein. Now, when we talk about whey protein, we’re essentially a 100% whey protein, no casein except for one fragment of casein that actually gets solubilized, as TJ described, and now actually becomes part of whey protein. Something that a lot of people don’t understand is that about 15% of what we call whey protein is actually a piece of casein that gets lost in the whey and now gets [00:07:00] captured and harvested in the whey protein manufacture process. But again, it’s important to remember milk protein is a 80 / 20 combination of casein and whey protein together. So, when you’re talking about milk protein, you’re actually talking about whey protein and casein together. Ted Jacoby III: It’s funny, I just learned something never really quite had my head around, and that’s that 80 / 20 ratio, that 80% of all the protein in milk is actually either alpha or beta casein. Correct? Lloyd Metzger: There’s actually four different casein fractions that are involved that make up that 80% of the total protein. Ted Jacoby III: Okay. The casein molecule isn’t really any bigger than most of the whey protein molecules, but they tend to clump together in those micelles. And so, they act as one big humongous mass compared to whey proteins. Correct? TJ Jacoby: Whey proteins may be collected like in pairs like two at a time, but casein proteins, there’s hundreds, right? Lloyd, that will just clump together. Thousands. TJ Jacoby: So, these spheres are absolutely massive protein complexes, but in fact there are a lot of little individual [00:08:00] proteins that make it up and they’re all bridged together with calcium and phosphate. Lloyd Metzger: It’s a packaging system that was designed to package up calcium and phosphorus. So, the whole casein system was designed by nature as a delivery vehicle for calcium and phosphorus, because calcium is not soluble by itself. Calcium phosphate is essentially rock. It’s the material that makes up eggshells. Think, think about a ground up eggshell that calcium phosphate complex is not soluble and it will sink to the bottom of your container of milk if you didn’t have the protein complex to hold it in solution. The analogy I use is it’s basically a kidney stone. Think about how much fun milking a cow would be if all the calcium and phosphorus was in the form of a kidney stone as you’re trying to milk the cow. All that calcium and phosphorus can be solubilized with the casein system and put it into solution and then make it so you can deliver that in a nutritional product. Ted Jacoby III: That makes perfect sense. That’s really cool. I think you guys also already touched on the differences in solubility as you were [00:09:00] describing the different proteins. But there’s differences in digestibility as well. What’s the source of that difference? TJ Jacoby: I’ll take this one. Returning back to the infant stage, I feel like we could set this up in light of why nature created these proteins. Dairy is the fundamental human food for infants. You have babies that can live up to a year off of just their mother’s milk. All the proteins that are found in there, those building blocks to grow an infant, can be boiled down to those two protein streams: whey protein and casein protein. The purpose of the casein protein for the infants is it’s fast acting. It’ll go right into the gut, and the gut is full of enzymes, but also really, really low pH, so low that it actually causes even those whey proteins to unfold. And It allows the stomach enzymes to break it up super, super fast and be absorbed. It’s considered one of the most bioavailable proteins known to man. It’s designed for that, that’s why nature created whey protein. Well, whey protein itself is also very nutritious. It has one of the highest concentrations of [00:10:00] essential amino acid, and the second highest known to man of branch-chain amino acids. That means it doesn’t have to be processed through the liver before it can be used by the human body. If your body’s actively using and consuming protein whey protein’s really good because it can be absorbed into your system and go right to the muscles. 33% of your muscle is branched chain amino acid. That’s what’s getting broken down while you’re working out. And then in the elderly, that’s what’s getting broken down that’s causing some muscle degeneration. Whey protein can help fortify that very quickly. However, all protein that is consumed in the body could also easily be processed through the liver with time. And so, if you have time, that’s where the casein comes into play. The casein, when it hits that acidic environment in the gut, it immediately clumps together. It actually creates cheese curds in the gut. And the reason why that’s so important is it slows down digestion so that slowly over time, that will be absorbed into the system. So it’s not [00:11:00] like a rush of energy right after the baby eats and then it goes away right away. Instead, it slows it down. The casein itself also likes to trap other nutrients. The casein in the gut will house the fat and the vitamins and the nutrients so that it’s slowly absorbed over the course of the next few hours before the baby’s next feeding. Ted Jacoby III: As a result of those digestibility differences, what are the differences in the amino acid profiles between casein and whey proteins? The body’s gonna need to break down most of that casein in order to absorb it. When the body breaks down that casein, what are the differences in the way that it absorbs some of those amino acid profiles and short-chain protein strands from the casein versus what’s readily bioavailable from the whey proteins? TJ Jacoby: Casein does not have the same percentage of those essential amino acids. It’s not as high, but it’s designed to be slow absorbing. Protein itself, it almost doesn’t matter the amino acid structure, as long as your body has enough of those vitamins and nutrients to absorb and to restructure it to [00:12:00] a different protein within the liver — that’s what your body needs. Most of us, the protein doesn’t have to be fast-acting. It’s not like our muscles are actively breaking down all the time. It can slowly be absorbed, be processed through the liver, and then used for almost any other function as long as we have all the vitamins and minerals that we need. Lloyd Metzger: Part of this huge shift we’re seeing in demand for protein, especially whey protein, this started 25, 30 years ago with bodybuilders and wanting to build muscle mass. And the realization that TJ mentioned: branch-chain amino acids are very important if you wanna rapidly put muscle mass on. It is also very important if you’re elderly or if you have sarcopenia where you’re starting to lose muscle mass. In those nutritional states, it’s really important to have high-level branch-chain amino acids, so you can put muscle on. Or if you’re on a GLP-1 medication where you’re not gonna be able to eat very much, you need a very efficient source of protein to build muscle mass. So there’s certain nutritional states where it is important to have branch-chain amino acids [00:13:00] and be able to get those from a protein like whey protein that has ’em at a very high level. But for the normal person, it’s not really all that relevant. You could get the protein you need from any protein that provides all the essential amino acids. Now, most plant proteins don’t do that. We’re talking about the difference between casein and whey protein. Both of them are an order of magnitude higher in nutritional quality than plant proteins because they have all the essential amino acids. And to TJ’s point, as long as you have the essential amino acids, the body can produce the non-essential amino acids from those essentials. Essential ones are amino acids the body can’t produce. You have to have those in the food you’re consuming to be able to produce the components you need. Josh White: We’ve got listeners from the dairy side of the equation and listeners from the utilization side that are making different products. And some of those customers are currently faced with the reality that a part of the equation for their adoption of whey proteins as an ingredient has shifted. The competition level’s very [00:14:00] high. They’re having more difficulty accessing some of it. And the price has changed quite a bit. And I think that when you’re talking about these products going into CPG applications as a lower inclusion rate ingredient, but with a lot of label power, being able to put whey protein, for instance, on that label, there’s several of them out there that are struggling to determine what the functional differences might be between the various dairy proteins. And what I’m afraid that is happening is some of these companies that are on the lower end of the value scale and can’t afford to keep up with all of the great products that are demanding whey protein or even milk protein, are gonnastart exploring alternatives outside of our space. and I think that we don’t want that, right? And what we’re seeing is this popularity of whey protein is driving a lot of customers for R&D projects to be asking us specifically for whey protein. And so help us understand what applications might make sense to use one, the other, or both. Lloyd Metzger: It completely depends on the product that [00:15:00] you’re after and the characteristics of the product that you want. Something like a beverage can go two different directions. So, if you’re gonna retort the beverage and put a lot of heat on it, you can’t do that with most whey proteins. They’re gonna gel. The most comparable protein to whey protein would be an egg protein. And everybody understands what happens when you heat eggs; they turn into a gel. So, whey proteins will happily do that. If you have a high enough concentration and you expose them to enough heat. Casein actually helps to protect whey protein from that coagulation. A lot of these high-protein beverages, they’re oftentimes a combination of casein and whey protein. They might alter the ratio a little bit from the 80 / 20. They might bump the whey protein up a little bit and have a 60 / 40 casein to whey protein. And so you’ll see ranges in that ratio of casein to whey protein, depending on the characteristics of the product that you’re actually after. The heat is a big piece of that. And then we go to pH as a big piece of what changes the functionality of casein to whey protein and makes you [00:16:00] change those ratios. Yogurt is another great example. You’ve got these super, super high-protein yogurts and a lot of cases they fortified with quite a bit of whey protein to be able to have more protein and still have the characteristics that you want in that product. In the protein bars, there’s all kinds of whey proteins there. In that application, you actually don’t even solubilize the protein. There’s hardly any water in that bar. It’s really almost a dry protein that has a plasticizer with it, some carbohydrates that actually make that edible. You’re almost eating a dry product. There’s a lot of food chemistry that goes into which product category you’re putting it in. There’s not this straight fast rule that you use whey proteins in this, you use casein and that. It depends on what food chemistry you use and how you put the blend together and then what processing you couple with that to get the characteristic that you’re actually after. Josh White: Can we spend a minute or two talking about the acidified products? They’ve gained a lot of popularity. The market potential is quite large. Can we talk a bit about the [00:17:00] differences between the clear WPIs and our traditional products? Lloyd Metzger: I wanna clarify the question. Are you talking specifically about whey protein only in the clear whey protein beverages versus the normal whey protein beverages? Ted Jacoby III: Yes. Lloyd Metzger: We really start to get into the weeds because we’ve got different whey products. So we’ve got whey protein concentrate. And then that comes in various forms. WPC 34 or WPC 80 are the most common. The 80 and the 34 correspond to how much protein on a dry basis those two products have. And they have whey proteins in the normal ratio that would be in the starting whey. Then we get into a group of products called whey protein isolates. And whey protein isolates go through an additional manufacturing process that allows you to purify the protein further and they’ll have more than 90% protein on a dry basis. And you may start to alter the ratio of the various whey proteins that were present in the starting whey. Now, when [00:18:00] we get into the clear whey protein isolates, we really start to alter the ratio of the proteins that are in there. We’ll also start to change some of the mineral profile of the components that are in that product. And then when we use those isolates in a formulation, we gotta be careful about all the other ingredients ’cause they’re gonna have an impact on whether or not the product is actually clear and whether or not it can be stable to heat. So, you can actually make whey protein stable to heat by controlling the mineral profile and controlling some of the processing conditions. You’re now taking a category of dairy ingredient and you’re starting to use technology IP to be able to provide specific functional characteristics that aren’t normally part of that ingredient. All of these may be called the same thing, and the basic consumer has absolutely no idea what the differences between all these things are. And when they’re looking at a label, they’re probably looking for the word whey protein, and that’s all they’re looking for. Josh White: As we’ve seen the market tighten up, we’ve seen [00:19:00] more inquiries and exploration about the use of pro cream,also called WPPC, also called WPC 70, so many different names. Definitely, in our experience, there’s quite a uniqueness as we originate this product from different manufacturers. Perhaps we can talk a bit more about what this product is and how it differs from the other proteins in the complex. Lloyd Metzger: I talked about WPC 80. That’s just the normal whey protein that we concentrate out of whey. And then, I mentioned whey protein isolate. To convert WPC 80 to a whey protein isolate, you use a filtration step called microfiltration. And in that microfiltration step, you remove any protein that is interacting with fat and take that out of the system. So, if you start with a normal WPC 80 and we’re gonna change it into a WPI. We are gonna go through a microfiltration process and we’re gonna lose about 25% of the protein that was there and all of the fat that was there. And [00:20:00] we’re gonna make a WPI out of that. And that WPI is gonna have about 75% of the protein we started with. The protein that we harvest out of that is actually pro cream. pro cream is just a byproduct of converting WPC 80 into WPI, and it’s gonna have about 25% of the mass of the protein that you started with, and all of the fat that was in that starting WPC 80 material. So that’s why you see it called high-fat WPC 30, and if you dry that down, it’s about a WPC 60. You can take that and blend that with WPC 34. You can do all kinds of things with that ingredient. Manufacturers are always trying to find a home for that. ’cause you’ve got a very high value product that’s easy to market in WPI. Ted Jacoby III: Lloyd, that pro cream, our hunch is there’s a lot more value in that pro cream than the market currently has its head around. Lloyd Metzger: they’re the same proteins that are in WPI, they’re just interacting with a fat. Now the fat [00:21:00] is very unique in that there’s quite a bit of phospholipid fat in there. And so there’s a lot of literature and research being done on the potential health benefits for brain development of phospholipids for infants as well as elderly to help with memory retention and actually help to prevent some Alzheimer’s effects. So, you see some companies starting to market that component that they’ve isolated. I think there is a lot of potential value there. But we’re in the early stages of where that’s gonna go. And you have some companies leading the way that are producing very specialized pro cream type products that are being used in infant nutrition or elderly nutrition. TJ Jacoby: But Lloyd, how do those phospholipids affect the shelf life of pro cream? Lloyd Metzger: They don’t help. The phospholipids are unsaturated fats or partially unsaturated and unsaturated fats are very easy to oxidize, so if they’re not handled properly, you’ll get very stale and oxidized off flavors in the product. It’s something you gotta be careful of. Ted Jacoby III: Oxidized fats, [00:22:00] another way to call that. That’s rancid, right? Yes. Lloyd Metzger: On its way to rancid. Josh White: Another selling point that people will make of the benefits of pro cream are IgGs. Can you guys explain a bit more of what that is to the layman? Lloyd Metzger: So, immunoglobulin is a protein that’s also present in milk. It’s really high in colostrum. It’s at very low levels in milk about 72 hours after the cow was started milking, the levels drop way down, but there is still a low level there. Those immunoglobulins are a very large protein. So when you go through your WPI manufacturing process, they’re gonna partition with that fat and that protein portion that you’re capturing. So they’re gonna go in that pro cream. Looking at the composition of IgG in the different waste streams, you’ll find it’s elevated in that pro cream portion. Now I’d be a little concerned about what kind of shape that IgGs in because you’ve seen a lot of heat [00:23:00] and different manufacturing conditions through that process. So you’d really have to be careful about what kind of claims you’re making based on what kind of shape that IgGs in. Mm-hmm. TJ Jacoby: For an infant, those IgGs will go right into the bloodstream. It’s whole proteins, but for us, it actually has to break up the protein entirely before it can be absorbed into our system. So what kind of functional benefits does IgG bring for an adult? I’d be curious to see what that literature entails. Mike Brown (2): Over the last couple decades, DNA technology has been used more and more to produce valuable proteins, often for medical use like insulin. Are we gonna see a point with the cost benefit of that kind of technology we’ll reach where we can actually use that to produce these whey proteins rather than using a cow? Lloyd Metzger: There’s different levels of concern depending on the particular protein. An individual protein and an individual soluble protein like beta-lactoglobulin and alpha-lactalbumin that are in [00:24:00] whey, those have more potential to be produced in a fermentation type process. ’cause they’re an individual protein. You can over express it, you can get a lot of that produced. But when you get to the complexities of multiple proteins that are in whey, that’s when it really becomes uneconomical to do that from a fermentation standpoint. ’cause you’ve gotta produce all of those individually, try to put ’em together, then purify ’em. What people forget is how efficient the cow is. The cow is essentially a walking fermentation tank that feeds itself, controls its own temperature, cleans itself up. All you’ve gotta do is get the milk out of it. When you look at all the steps that go into the process and what it takes to produce it, it’s really hard to beat the efficiency of a cow. Ted Jacoby III: Lloyd, am I right in assuming that the threat of cellular agriculture to dairy would come in the development of specific protein chains and amino acids, but probably not in terms of the complete [00:25:00] protein profile that is delivered in milk proteins and whey proteins. Lloyd Metzger: Correct. And it would be the very high-end, expensive. So the lactoferrin. It would be your first one or some of the IgG, anything that is at low concentration and very high value. Because even if you did everything perfectly, you’re probably still talking $25 to $30 a pound in the manufacturer and isolation process. Well, we we’re really excited about $11 whey protein isolate. Right? You know, and that’s still half the price. Ted Jacoby III: Makes sense. Lloyd, TJ, this was an absolutely fantastic discussion. This was exactly what I wanted to get out of it. I can tell you I learned quite a bit today and I’m sure our listeners will too. Thank you so much for joining us. We really appreciate it. Lloyd Metzger: No problem. Happy to do it. TJ Jacoby: Truly special to be on today, Dad. I grew up listening to a lot of these podcasts, right? Now we’re here, now we’re on it together with you. So, no, it was truly special.[00:26:00]

This episode features Dr. Jocelyn Johnson with STgenetics, a speaker at the 2025 ADSA Breeding and Genetics Symposium: Creating Carbon-Friendly Cows and Leveraging Omics to Improve the Sustainability of Dairy Production.Dr. Johnson's presentation was titled “Advancing dairy sustainability through feed-efficient genetics and genomics: Research insights and applications.” She gives an overview of her talk, which focused on data STgenetics has collected and how the company has applied that data to help their customers be more sustainable. She goes on to describe some of the residual feed intake research they've conducted in dairy cows. (4:20)STgenetics has invested in feed efficiency technology and has shown that selection for improved feed efficiency is correlated to a lower carbon footprint. Dr. Johnson talks about the heritability of feed efficiency compared to other traits we select for in the dairy industry.  (8:16)Dr. Pralle asks Dr. Johnson if STgenetics is measuring emissions from cows in their research. The company has partnered with Texas A&M to measure methane emissions in heifers divergently selected for feed efficiency. They found that more efficient animals produced less methane. Since that pilot project, STgenetics has purchased equipment to measure emissions at their own research facilities and has collected 2-3 years of data on beef, beef on dairy, and Holstein populations. Dr. Johnson emphasizes that the relationship between methane emissions and high milk production is somewhat of a balancing act. (11:29)The group discusses feed additives purported to decrease methane emissions and the differences in rumen microbiomes between high and low efficiency animals. They also talk about how best to get information and technology in front of producers.  (17:59)Panelists share their take-home thoughts. (23:39)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Eve gives an overview of current and future consumer trends where dairy can play a role. Functional foods, health and wellness, high protein foods, fermented and cultured foods, women's health, brain health, and aging are all part of the mix. (7:26)The panelists discuss the healthfulness of saturated fats, the resurgence of butter, milk's bioactive compounds, and how best to reach the public about the health benefits of dairy. (10:41)Eve talks about marketing to Gen Z consumers, who are motivated by novelty. How do we reimagine a food that's been here for thousands of years? What new ways can we talk about it? What ways can we optimize dairy science and research to show up in generative systems like ChatGPT? (20:34)The group then tackles the topic of lactose. Lactose and honey are the only two sugars not made by plants. Why is it lactose that is in the milk of mammals? Dr. Jiminez-Flores thinks lactose is a dark horse in dairy and we have much yet to discover about it. He notes that some milk oligosaccharides are not digested by babies, but are used by bacteria in the development of a healthy microbiome. Dr. Lucy notes that dairy also contains peptides that have been found to reduce hypertension. The group also delves into how dairy products can be part of preventative health care. (23:53)Do consumers perceive dairy products to be minimally processed? Eve explains that dairy is perceived as a clean, fresh food. Given the current trend to reduce additives and food dyes, she sees potential for dairy food science innovation in this area. Dr. Aldrich talks about the glycemic index of lactose-free milk. (38:13)The panelists agree that dairy has a great upcycling story to tell. Converting fiber into milk and meat and feeding non-human grade byproducts are just two examples. Eve notes that younger consumers care about sustainability, but there's a huge “say-do” gap: 76% of North American consumers identify as caring about conscious and sustainable practices, but less than 40% actually act on those values when making purchases. The panel also notes that whey is another great upcycling story. Dr. Jiminez-Flores emphasizes how important consumer trust in science and research is, and how we are currently experiencing a loss of that trust. (45:48)Panelists share their take-home thoughts. (1:01:01)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Dr. Lock presented a Real Science Lecture Series webinar on June 3, 2025. This episode takes a deep dive into the current science and applications of feeding high-oleic soybeans in dairy diets. You can find the original webinar at balchem.com/realscience. Dr. Lock gives an overview of the evolution of our knowledge of biologically important fatty acids in dairy cows. Much like we think more about amino acids than crude protein these days, we are starting to think about fatty acids rather than crude fat. There are 5 main fatty acids in dairy cow diets: palmitic, stearic, oleic, linoleic, and linolenic. Dr. Lock talks about the importance and role of each, especially that of oleic acid. (6:26)  Dr. Bales shares some of the research she conducted in Dr. Lock's lab during her MS and PhD, including a dose response study, raw versus roasted beans, and roasted beans plus supplemental palmitic acid. All studies have resulted in increased milk fat and milk yield, better feed efficiency, and usually a bump in milk protein. She also notes there is a nice synergistic relationship between the fat and degradable protein in the roasted high-oleic beans, which are high in lysine. (13:59)Nate talks a bit about how the elevator positions high-oleic soybeans to the dairy producers in the area and how different farms have implemented feeding the beans, depending on size, infrastructure, and location. Dr. Bales chimes in with some additional examples. (21:02)The panelists agree that quality control to ensure consistent sources going out into the field is the next big hurdle. Finding the optimal particle size for diets is also needed, as there is a wide variation currently, which may impact cow performance. (31:56)Nate predicts no slowing down in the adoption of this technology in his area in the next few years. Dr. Lock notes there may be some potential for feeding high-oleic oil in areas not suited for growing the beans themselves. The panelists agree that the target groups who should receive high-oleic beans in their rations are fresh cows and high cows. Nate emphasizes the importance of having adequate digestible NDF and a healthy rumen to see optimal results. (37:10)Dr. Lock talks about future research plans into high-oleic soybeans and other fatty acids. The panel comments on the yield of high-oleic soybeans and the availability of seed, both conventional and GMO. (48:48)Panelists share their take-home thoughts. (59:15)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this episode of The Dairy Podcast Show, Jennifer Weber from Afimilk discusses how data-driven technology is transforming dairy management. She explains how feed efficiency algorithms and cow-level data are transforming breeding, replacement strategies, and sustainability strategies on farms. Discover how digital tools are redefining productivity and profitability in the dairy industry. Listen now on all major platforms!"We can confidently say now in the general market, we were able to get a 94% accuracy on individualized dry matter intake."Meet the guest: Jennifer Weber is the Director of Customer Success and Midwest Commercial Manager for Afimilk USA. She leads operations and customer success initiatives across North America. With a dual background in Dairy Science and Biochemistry from the University of Wisconsin–Platteville, Jennifer brings years of experience in integrating technology into dairy operations. Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:41) Introduction(05:13) Feed efficiency innovation(07:31) Data and sensors(09:12) On-farm applications(11:41) Long-term strategy(18:06) Future technologies(01:41) Final three questionsThe Dairy Podcast Show is trusted and supported by innovative companies like:* Afimilk* Evonik* Priority IAC* Lallemand* Adisseo- Berg + Schmidt- SmaXtec- dsm-firmenich- ICC- Protekta- AHV- Natural Biologics

In this episode, we showcase student research at the 2025 ADSA Annual Meeting in Louisville, Kentucky. Abstracts can be found here: ADSA 2025 Annual MeetingAbstract 2186: Effects of feeding alternative forage silages on early lactation performance and gas production in multiparous Holstein cows. (00:15)Guests: Barbara Dittrich and Dr. Heather White, University of Wisconsin-MadisonCo-Host: Dr. Clay Zimmerman, BalchemBarbara substituted rye silage, triticale silage, rye-camelina-hairy vetch silage, and triticale-camalina-hairy vetch silage to replace 10% of the alfalfa silage in the control diet for her experimental diets. Dry matter intake and gas production were similar across diets. Average milk yield was higher in the rye mix silage group compared to the triticale mix silage group, but no treatment was different than the control.  Abstract 1602: Optimizing starch concentrations in low-forage diets. (11:22)Guests: Irie Moussiaux and Dr. Kirby Krogstad, Ohio State UniversityCo-host: Dr. Jeff Elliott, BalchemIrie investigated different levels of starch in a low-forage diet (12.5% NDF) by replacing soybean hulls with corn to yield 20%, 25%, or 30% starch. Dry matter intake and milk production were the same for all three starch concentrations; however, the low starch diet had the highest milk fat yield and energy-corrected milk yield. Abstract 2183: Effects of partial replacement of corn and oat silages with extracted stevia plant on production, behavior, and digestibility in dairy cows. (17:05)Guests: Mariana Marino and Dr. Jose Santos, University of FloridaCo-host: Dr. Clay Zimmerman, BalchemMariana fed stevia plant byproduct as a replacement for corn and oat silage in lactating cow diets. All diets had 40% grain and 60% forage. Stevia byproduct was included at 0, 25%, or 40% of diet dry matter. The byproduct is of very fine particle size and is relatively high in lignin. This resulted in higher dry matter intake, but lower milk production for the highest stevia diet. Abstract 2472: Evaluating feed sorting behavior and TMR composition in roughage intake control feeding systems. (26:38)Guests: Sophia Green and Dr. Heather White, University of Wisconsin-MadisonCo-host: Dr. Ryan Pralle, BalchemSophia evaluated feed sorting in a research intake control feeding system (RIC bins). Feed sorting primarily occurred in the last 12 hours of the feed day, and particle size was smaller at the end of the day than earlier. Compared to fresh feed at hour zero, the chemical composition of the diet did not change throughout the feed day. RIC bins did not introduce additional variance in nutrient consumption. Abstract 1603: Assessing an ex vivo assay with gastrointestinal tissue sections to investigate mucosal immune responses in dairy calves. (35:24)Guests: Paiton McDonald and Dr. Barry Bradford, Michigan State UniversityPaiton challenged explants from the ileum and mid-jejunum in the lab with rotavirus or E. coli compared to a control. Pathogen stimulation increased mRNA abundance of TNF and IL6 above control. Ileal sections secreted more cytokines than jejunal sections. Abstract 1466: The short-term effect of increasing doses of palmitic and stearic acid on plasma fatty acid concentration and mammary arteriovenous difference in Holstein cows. (40:17)Guests: Alanna Staffin and Dr. Kevin Harvatine, Penn State UniversityCo-host: Dr. Jeff Elliott, BalchemAlanna fed mid-lactation cows 0, 150, 300, 500, or 750 grams of palmitic acid, stearic acid, or no supplement control. Palmitic acid increased milk fat yield at lower doses compared to stearic acid. Alanna found that the mammary gland increases its arteriovenous (AV) difference and uptake of palmitic acid when higher concentrations are provided, but AV difference and uptake of stearic acid did not change. Abstract 2006: Does hay improve performance in pair-housed dairy calves? (50:00)Guests: Gillian Plaugher and Dr. Melissa Cantor, Penn State UniversityGillian fed pelleted hay to pair-housed dairy calves along with milk replacer and calf starter. Control calves received milk replacer and calf starter only. Hay-fed pairs grew faster than controls after day 21 and were heavier at day 70. Hay feeding did not impact calf starter DMI or feed efficiency. Abstract 1463: Dietary metabolizable protein and palmitic and oleic acids affect milk production in early lactation dairy cows. (1:02:03)Guests: Jair Parales-Giron and Dr. Adam Lock, Michigan State UniversityCo-host: Dr. Clay ZimmermanJair fed two different levels of metabolizable protein and 3 different levels of supplemental fatty acids from 1 to 22 days in milk followed by a common diet to evaluate carryover effects to day 50. Metabolizable protein and fatty acid supplementation had additive effects on milk production. Cows fed the highest dose of both metabolizable protein and fatty acids produced 8.9 kg more energy-corrected milk per day compared to the low metabolizable protein diet without fatty acid supplementation.

This episode features speakers from the 2025 ADSA Opening Session Panel: Designing Dairy 2045—Envisioning the Future of Cows, Dairy Products, and Farms, which explored the long-term future of dairy.Dr. VandeHaar explains the idea behind creating the panel discussion for the opening session and his selection of the other three podcast guests as panel members. (2:02)Dr. Baes was the genomics expert on the panel. Her talk focused on what types of data have been collected on dairy cattle in the past and in the future, as well as the collaboration needed among different disciplines to ensure the right information is being collected in the appropriate way. (4:54)Dr. Hostens was the data analytics expert on the panel. He is a veterinarian by training, but has a strong interest and passion around big data. He notes that a “gut feeling is good, but data is better.” He talks about a project where an existing language model was trained with all Journal of Dairy Science abstracts since 1917 so that answers from chatbots would be fed by JDS knowledge. He talks about other ways this type of approach could be used in the future to provide answers to questions on-farm. (8:09)Eve is the Senior Vice President of Strategic Intelligence at DMI and was the food futurist expert on the panel. She notes that dairy's image is shifting to that of a health and wellness food. The question then becomes what is the future of health and wellness, and what does the dairy industry need to do to build towards that future? She talks about the roles of data and artificial intelligence in enabling us to design the foods of the future tailored to each individual. She advises that knowing more about your product than anyone else on the planet through technology and science allows you to anticipate what consumers are going to want and need in the future.   (14:33)The panel talks about genetic selection to produce particular components “naturally” rather than through food processing, where the industry is headed in regard to total milk production, breeding dairy cows for health, providing tools for making wise use of resources especially in developing countries, and how the future of big data could impact decisions made on-farm. (20:12)Eve talks about the consumer who has (processed) collagen in their coffee each morning but also demands clean, whole foods. Consumers want it all. She envisions a future where consumers will know the truth about how foods work in their body because they'll have the technology to measure it. The group goes on to talk about wearable technology like continuous glucose monitors and the variability that exists in the human population compared to variation in Holstein cows, for example. (35:05)The guests talk about where the gaps are in technology - what else do we need to take the next step? Dry matter intake might be one, but Dr. Baes notes that the Danish have technology through video of the feed bunk that allows them to predict intake with surprisingly high accuracy. (41:59)Panelists share their take-home thoughts. (47:07)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this episode of The Dairy Nutrition Blackbelt Podcast, Gaelan Combs, a PhD student at Iowa State University, discusses the impact of dexamethasone pre-treatment on metabolism and productivity during a systemic immune challenge. He examines how inflammation affects productivity and why immune activation involves more than just inflammatory markers. Listen now on all major platforms!"Inflammation is one of the key responses that happens when the immune system is activated, but it's not the only factor involved."Meet the guest: Gaelan Combs is a PhD student in Animal Nutrition at Iowa State University, where his research focuses on immune activation and its metabolic effects in dairy cattle. He earned his Bachelor's degree in Dairy Science from the University of Wisconsin–Madison, where he conducted undergraduate research in dairy nutrition. Liked this one? Don't stop now — Here's what we think you'll love!What will you learn: (00:00) Highlight(01:24) Introduction(03:31) Immune activation effects(04:06) Inflammation and productivity(04:51) Dexamethasone's role explained(06:19) LPS challenge model(11:19) Inflammation vs immune activation(13:24) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Adisseo* Priority IAC* Fortiva- Virtus Nutrition- Kemin- Zinpro

In the Real Science Exchange Legacy Series, we celebrate the pioneers who have shaped the dairy industry. In this episode, we honor Dr. Bill Weiss, professor emeritus at The Ohio State University. This episode was recorded at the 2025 ADSA annual meeting in Louisville, Kentucky, where Dr. Weiss received the 2025 ADSA Award of Honor. Dr. Weiss shares about his early life, schooling, and academic career. (2:29)Panelists introduce themselves and how they know Bill. Dr. Firkins started at OSU one month before Dr. Weiss, Dr. St. Pierre was in graduate school with Dr. Weiss, and Dr. Tebbe was Dr. Weiss's last graduate student. (4:47)Dr. St. Pierre and Dr. Firkins share about Bill's deep contributions to the science of energy, protein, and trace mineral nutrition in dairy cattle. They note he was a great mentor to his students and an exceptional colleague. Dr. Weiss reflects on his career and the collaborations he had with his colleagues even though they were on different campuses. Dr. Tebbe underlines what a hard worker Dr. Weiss is, yet always had time for his students. (11:45)Panelists share stories about Bill's driving, winning 20 gallons of ice cream in a contest in graduate school, Bill's less serious side, and his love for cars and golf. They also tease him a bit for being a glutton for punishment and serving on both the 2001 NRC and NASEM committees. (19:06)Panelists share their take-home thoughts. (29:11)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode features speakers from the 2025 ADSA Applied Nutrition Symposium, “Milk Pricing Dynamics and Strategies for Enhancing Milk Fat Production.” Dr. Lock gave the highlights of his presentation on dietary opportunities for promoting milk fat.  (2:18)Dr. St. Pierre's presentation focused on the change we've had in the way milk and its components are priced. (5:25)Dr. Van Amburgh's symposium talk covered amino acid supplementation to high producing cows eliciting more of a milk fat response than a milk protein response. (9:31)Dr. Van Amburgh and Dr. Lock talk about where butyrate fits into milk fat synthesis. Dr. Van Amburgh shares some of his experiences with grass-based dairy diets in Ireland and how those might influence milk fat production. The group discusses de novo and preformed fat synthesis and how diets may or may not influence those two mechanisms. (12:16)The guests talk about an abstract from Dr. Van Amburgh's lab at the ADSA meetings about supplemental lysine levels. This leads into a discussion of lactose production and fluid milk volume, as well as feedback from cheese processors and the impact of supplemental chromium on milk production parameters. (22:31)Dr. St. Pierre talks about cheese processor concerns with increased milk fat concentrations, milk pricing structures, and milk perishability. (28:27)The panel discusses metabolizable protein, essential, non-essential, and branched-chain amino acids, and how the view of fatty acids and amino acids has changed from simple substrates to make milk components to compounds with biogenic activities. (36:20)Dr. St. Pierre talks about the inaugural Industry Day at the 2025 ADSA meetings and goals for similar future events. (43:01)Panelists share their take-home thoughts. (48:13)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt. 

In this episode, we feature some of the winners of poster and oral presentation competitions at the 2025 ADSA Annual Meeting in Louisville, Kentucky. Abstracts can be found here: ADSA 2025 Annual MeetingMS Oral Presentation, ProductionGuests: Trinidad Fernandez-Wallace and Dr. Lautaro Rostoll-Cangiano, University of Wisconsin-MadisonCo-host: Dr. Laura Niehues, BalchemAbstract 1218: Immunity at the crossroads of cellular metabolism: Navigating T helper shifts in the periparturient period of dairy cows. (0:08)Trinidad found that T-helper cell metabolism and proliferation were both upregulated after calving, which may impact the effectiveness of immune responses during the transition period. The group discusses if T-helper cells could be used as a marker of inflammation in the future and how Trinidad's results may have been different if samples had been collected between 3 and 28 days after calving.PhD Oral Presentation, ProductionGuests: Natnicha Taechachokevivat and Dr. Rafael Neves, Purdue UniversityCo-host: Dr. Sion Richards, Balchem Abstract 1107: Relationships between systemic inflammation, subclinical hypocalcemia, and hyperketonemia in clinically healthy Holstein cows. (8:07)Natnicha investigated the association of plasma haptoglobin (an inflammatory marker) on days 1 and 3 in milk with subclinical hypocalcemia and hyperketonemia. Systemic inflammation appears to be associated with subclinical hypocalcemia and hyperketonemia and reduced milk yield in multiparous cows. When multiparous cows exhibited both inflammation and metabolic disease indicators, they produced less milk; however, when primiparous cows exhibited both inflammation and metabolic disease indicators, they produced more milk. 3 Minute ThesisGuests: Savitha Saikumar and Dr. Diwaker Vyas, University of FloridaCo-host: Dr. Laura Niehues, BalchemAbstract 1548: Effects of peripartal supplementation of prototype postbiotics on intake, rumen fermentation, colostrum quality, and performance in transition dairy cows. (15:14)Savitha investigated the effects of a prototype postbiotic supplement in transition cows from 35 days before calving to 63 days after calving. Cows on the postbiotic treatment received 25 grams per day topdressed on their TMR. Before calving, the postbiotic had no effect on dry matter intake, body condition sore, body weight, or total VFAs. After calving, the postbiotic increased dry matter intake and milk yield after 6 weeks, and increased energy-corrected milk and fat-corrected milk with no effect on body weight, body condition score, or rumen fermentation profile.PhD Poster Guest: Amanda Fischer-Tlustos, University of Guelph Abstract 2012: Characterization of dry-period mammary acetate and glucose metabolism and their association with colostrum production in multiparous Holstein cattle. (25:15)Amanda's research evaluated acetate and glucose metabolism in the mammary gland during the dry and calving periods to better understand how colostrum is made. Acetate uptake by the udder remained fairly constant until one week before calving, when it started to increase. Glucose uptake did not increase until the onset of calving. Previous lactation milk production and far-off mammary metabolism were both negatively correlated with colostrum production. Amanda hypothesizes that high producing cows who have trouble drying off may have high amounts of metabolic activity in the mammary gland when they should have low activity, which may result in lower colostrum production at the subsequent calving. PhD Oral Presentation, Southern Branch DivisionGuests: Bridger Sparks and Dr. Clarissa Strieder-Barboza, Texas Tech UniversityCo-host: Dr. Ryan Pralle, BalchemAbstract 1215: Adipose tissue neuro-like cell profile changes with ketosis in dairy cows. (33:05)Bridger investigated neuro-like cells in the adipose tissue of cows with or without subclinical ketosis. The transcriptional profile of neuro-like cells changed when collected from cows with subclinical ketosis, which may indicate a potential regulatory role in adipose tissue metabolism. Perhaps modulation of neuro-like cells could potentially alleviate excessive adipose mobilization in the postpartum period. ADSA Graduate Student Division HighlightsGuests: Evelyn Yufeng Lin, North Carolina State University; Miranda Farricker, Cornell University; Conor McCabe, University of California-Davis; Dr. Maurice Eastridge, Ohio State University. (40:45) Dr. Eastridge is the chair of the ADSA Foundation and explains some of the Foundation's current projects. Evelyn and Conor are past presidents of the ADSA Graduate Student Division, and Miranda is the incoming president. Each student gives a bit of background on themselves and their research and describes what the Graduate Student Division does and how they foster new graduate students in ADSA.  Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Dr. Dahl presented a Real Science webinar on heat stress on April 1, 2025. You can find the webinar at balchem.com/realscience. This episode of Real Science Exchange further explores the key elements of Dr. Dahl's webinar.Dr. Dahl talks about geographical differences in whether farms provide cooling for dry or lactating cows. Cows get heat stressed long before humans. Some farms are concerned that using misters for cooling will add too much water to their manure handling systems. He notes a study comparing conventional misters and fans, no cooling, and smart soakers that only provide mist if a cow is present. When the total amount of water (drinking + cooling system) was evaluated, the smart soakers cooled as well as the conventional system, but used the same amount of water as the no cooling group.  (7:08)During the dry period, a main impact of heat stress is a reduction in dry matter intake. However, there are dramatic shifts in immune function and effects on mammary development and redevelopment in cows who experience heat stress in the dry period. This sets the stage for lower productivity in the next lactation. In addition, there are many negative impacts on the in utero calf from heat stress. Calves from heat stressed dams are challenged from a growth standpoint, in addition to organ development challenges in the mammary gland, ovaries, and immune system. These calves are less likely to make it through their first lactation, are less productive, and pass their poor production and survival phenotype on to their offspring. (14:28)Dr. Tao talks about when during the dry period to provide cooling for cows. Spoiler alert: the entire dry period! He also notes that bred heifers should have cooling provided for the last 60 days of gestation as well. Laura asks about the impact of heat stress on neonatal calves and how it may impact their mammary development. More research is needed in this area, and you also have to wait two years to collect data from the first lactation. Dr. Dahl notes that observations from season of birth data indicate lower longevity for calves who are born to heat stressed dams. (18:26)Milk production is decreased by 8-10 pounds per day for cows stressed during the dry period, and they also produce a lower volume of colostrum. Calves from heat stressed dams also have a lower rate of passive transfer of antibodies from colostrum. The panel talks about why that might be, whether or not those gut differences persist after calfhood, and how that might be related to growth differences between heat stressed and cooled calves. (27:30)What about reproduction? It appears that heat stress during the dry period has a negative impact on reproductive function in the subsequent breeding season. Recent research has indicated that calves experiencing heat stress in utero have poor gonadal development and lower follicular reserves. In addition, placental development is also negatively affected. Dr. Tao notes that heat stress negatively impacts mammary gland involution during the dry off period. All of this leads to a decrease in cow longevity. (35:36)Dr. Dahl describes a retrospective records study using Florida and California herds to evaluate cows in their fifth through eighth lactations. In Florida, about three-quarters of those animals were born in cooler parts of the year rather than in hotter months of the year. The pattern in California was similar, though not quite as extreme. (44:02)Dr. Tao and Dr. Dahl expand on the economics of cooling cows, including return on investment and the costs of not cooling. The guests also talk about some of their research abstracts at the 2025 ADSA meetings. (48:10)Panelists share their take-home thoughts. (57:41)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this episode of The Dairy Podcast Show, Dr. MaryGrace Erickson discusses sustainability challenges and opportunities within modern dairy production. She explores how protein nutrition, manure management, and farm-level decisions intersect to shape greenhouse gas emissions and nutrient cycles. Dr. Erickson also highlights the importance of integrating economic, environmental, and social perspectives in dairy systems. Listen now on all major platforms!"Sustainability isn't just about emissions; social and economic factors must be part of the equation too."Meet the guest: Dr. MaryGrace Erickson is a Dairy Nutritionist at CSA Animal Nutrition, specializing in sustainability, nutrient management, and precision feeding for dairy systems. She completed her PhD in Dairy Science at the University of Wisconsin-Madison after earning her Bachelor's and Master's degrees at Purdue University.Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:30) Introduction(08:05) Manure management(09:44) Solid-liquid separation(12:09) Protein nutrition & nitrogen(19:10) Management challenges(23:14) Sustainability impacts(34:37) Final three questionsThe Dairy Podcast Show is trusted and supported by innovative companies like:* Evonik* Priority IAC* Adisseo* Afimilk- dsm-firmenich- Berg + Schmidt- Natural Biologics- SmaXtec- Protekta- ICC- AHV

This episode was recorded in Fort Wayne, Indiana, during the 2025 Tri-State Dairy Conference.Dr. Fessenden gives an overview of his presentation which covered both research and field information on automated milking systems. He recommends going back to basics and formulating a rumen-friendly PMR with a complementary palatable feed that encourages the cows into the robot system. (5:57)The panel discusses ideas for driving cows to the robot on different types of PMRs, management of transition and late lactation cows in automated milking systems, and the use of custom pellets versus other supplemental feeds in the robot. (9:04)Dr. Fessenden talks about some of his experiences visiting automated milking systems in Europe and some of the differences between European and North American approaches to diet formulations in automated systems. The group goes on to talk about different options for supplemental feed formulations in the robot. (18:38)Dr. Fessenden and Dr. Tylutki share ideas for how feeding technology could help both traditional and automated milking farms in the future. They discuss more precise grouping of cows and targeted feeding of those groups to better match requirements, as well as how movement to different pens and diet changes can impact milk production. (23:45) Dr. Tylutki updates the group on advancements in the AMTS balancing tools for multiple robot feeds. He and Dr. Fessenden describe the challenges of developing new tools that are streamlined and user-friendly for nutritionists. They also delve into the role artificial intelligence and machine learning might play in ration balancing in the future. (29:32)Dr. Fessenden encourages nutritionists to think outside the box when working with automated milking herds to make decisions that are right for that particular farm. Dr. Tylutki chimes in with advice to spend time actually watching the cows on the farm, and Dr. Van Soest echoes this sentiment when it comes to troubleshooting issues with the robots themselves. Don't just assume it's an issue with the ration - ask or observe for yourself what may have changed on the farm that could contribute to the issue the farm is facing. (40:02)Panelists share their take-home thoughts. (45:20)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded in Fort Wayne, Indiana, during the 2025 Tri-State Dairy Conference.Dr. Schwanke begins by describing how we can shape cattle personalities through handling and management and adapting our strategies to accommodate different personality traits so as to not cause undue stress. Personality traits are consistent across time and context, which is nuanced by the other animals in a particular group. There are five generally recognized personality traits: boldness, exploration, activity, sociability and aggressiveness. Some debate exists as to whether dominance should be considered a sixth trait or if it's just an outcome of the other five. (5:43)Dr. Schwanke's research focused mainly on how cows react to specific stressors, such as adapting to an automated milking system. In a robotic system, cows who are more independent, explorative and bold are more likely to do well. Some diversity is good because it can help to minimize long-term antagonistic interactions in a group. If we have cows that are very similar to each other, it will take longer for them to establish a social hierarchy.  (10:05)The panel discusses where the research is in regard to on-farm applicability and potential genetic components of personality traits. In the future, Dr. Schwanke envisions automated assessments of cow personality through computer vision cameras in the barn, fed into an algorithm that creates a personality ranking of cows based on their behaviors. She also notes personality traits can help predict a cow's coping style: proactive, reactive and intermediate. Proactive cows are more bold, explorative and aggressive. They thrive in predictable, stable conditions. Reactive cows are more fearful, less active and less dominant. They typically do better than proactive cows in unpredictable or changing environments because they're better able to modify their behavior to the environment they find themselves in. (14:09)The panel talks about future research goals in this area, including transition to automated milking systems, modifying feed management for behavioral and nutritional requirements and impacts of commingling stress. The guests also explore behavioral research in calves and brainstorm about future research with this age group, as well as talk about potential implications of making the wrong selection decisions for personality traits. (20:08)Are there things dairy producers could do to condition calves to be more adaptable to an automated milking system later in life? If a calf is reared in an automated feeding system, do they adapt to an automated milking system more easily? We don't have the research yet to answer these questions, but they're great questions. The panel also talks about how to scale up personality trait information to large herds, how precision feeding systems and personality traits might interact and how machine learning and computer vision technology can automate personality trait assessments. (28:46)Panelists share their take-home thoughts. (35:02)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Have you ever heard of “wood milk”? Well, it's a joke, but a pretty controversial one. Dairy isn't the only option for your milk these days, much to the chagrin of the USDA and the dairy industry. But there are so many options to choose from, it can make your head spin. What's the environmentally-friendly choice? And are they more expensive than cow's milk? Take a bath in some plant-based milk (mylk? melk? milkk?) this week.SourcesWood Milk (fictitious): https://www.drinkwoodmilk.com/ World Resources Institute: https://www.wri.org/insights/milks-environmental-impact It's Nice That: https://www.itsnicethat.com/news/milkpep-wood-milk-complaint-pcrm-advertising-food-drink-300523 New Roots Institute: https://www.newrootsinstitute.org/articles/dairy-checkoff-programs YouTuber @DaraDenney: https://youtube.com/shorts/zJVPwvrl9Sg?si=rMJz-VRZOogYKdcG Fast Company: https://www.fastcompany.com/40556502/got-milk-how-the-iconic-campaign-came-to-be-25-years-ago Journal of Dairy Science: https://pmc.ncbi.nlm.nih.gov/articles/PMC7094284/The Humane League: https://thehumaneleague.org.uk/article/what-happens-to-male-calvesUniversity of Wisconsin Madison: https://livestock.extension.wisc.edu/articles/disbudding-calves/ National Dairy Farm (FARM) Program: https://nationaldairyfarm.com/dairy-farm-standards/animal-care/ Yahoo!: https://www.yahoo.com/lifestyle/heres-why-oat-milk-expensive-191508011.html Love and Lemons: https://www.loveandlemons.com/oat-milk/#wprm-recipe-container-42113Epicurious recipe: https://www.epicurious.com/recipes/food/views/homemade-soy-milk-andrea-nguyen Patreon: patreon.com/greeningupmyactInstagram: @greeningupmyactFacebook: Greening Up My ActEmail us with questions: greeningupmyact@gmail.comYouTube: Greening Up My Act

This episode was recorded in Reno, Nevada, during the 2025 Western Dairy Management Conference.Dr. Hutjens' presentation focused on herds producing seven pounds of milk fat and milk protein per cow per day, and the genetics, on-farm management and nutrition to make that happen. The panel discusses where components could top out, how added dietary fat has influenced components and the importance of high quality forage to de novo fat synthesis. (4:09)The panel explores how well nutritionists are keeping up with rapid genetic change in milk component production and how farmers respond to recommendations for things like rumen-protected fatty acids and supplemental fat. Dr. Nelson shares some of the unique challenges and opportunities faced by the California dairy producers he works with. (11:56)Dr. Hutjens gives some benchmark values for energy and protein efficiency. The panel debates the merit of energy-corrected milk per stall as an efficiency measure, with the consensus being it might lead to crowding, which would then probably decrease milk and component production due to decreasing cow comfort. The group also discusses selecting for feed efficiency and the heritability of feed efficiency. (16:33)The panel dives into the topic of feed ingredients. High-oleic soybeans and high quality forages are a focus in some parts of the country. Dr. Nelson discusses non-forage fiber sources available in the California market, such as citrus, plums, apples and carrots. The group talks more about how high-sugar byproducts influence rumen fermentation, which is different from starch, as well as benefits in palatability, digestibility and intake. (21:03)Dr. Hutjens talks about benchmarks for milk components and different strategies for increasing component production. Rumen-protected amino acids, purchased fats, roasted high-oleic soybeans and urea are discussed. The group also talks about what might happen if milk processors start asking for less milk fat, for example. Dr. Hutjens talks about how nutritionists can help balance rations to yield different results for different markets. (33:04)Panelists share their take-home thoughts. (40:33)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded in Fort Wayne, Indiana, during the 2025 Tri-State Dairy Conference.Dr. Boerman notes we know cows experience a negative metabolizable protein balance in early lactation, which means they're mobilizing skeletal muscle to make up for that. Dr. Boerman and her group have been interested in strategies to measure how much muscle they're mobilizing, when they're losing it and when they gain it back.  (3:51)Cows are ultrasounded during the dry period to determine longissimus dorsi muscle reserves, then divided into low vs high muscle groups. Weekly ultrasounds follow them through lactation.  Animals with high muscle reserves during the dry period mobilized muscle before calving, which resulted in increased calf birth weights. Animals with less muscle during the dry period can gain muscle during that time and have more muscle reserves at calving than they had in the middle of the dry period. Dr. Boerman discusses possible nutrition interventions to manage muscle depletion and accretion, as well as timing of muscle loss and gain.  (5:14)The panel discusses how cows were assigned to high- and low-muscle groups and how representative those groups might be to the general population of dairy cows. Dr. Boerman mentions they've recently started evaluating primiparous cows as well to see if they perform differently than multiparous cows. (10:33)Dr. Boerman notes that cows are mobilizing between 30 and 35% of their longissimus dorsi depth during lactation and muscle biopsies have shown a reduction in muscle fiber size. They also measure 3-methyl histidine and creatinine as biomarkers of muscle loss and gain. The panel discusses increased calf birth weights and impacts on colostrum for high-muscle groups. Body condition score is not a good predictor of muscle depth. (16:52)The group discusses how parity might impact protein loss and gain, the influence of genetics on these muscle measurements, how health events might affect muscle mobilization and what kind of hormonal regulation might be occurring to control muscle losses and gains. (23:41)Dr. Weiss shares about a project from his group where muscle and fat losses were measured by dilution. They fed 20% protein diets using soy alone or with supplementation of rumen-protected amino acids. He emphasized the differences between heifers and cows, similar to what Dr. Boerman's group has observed as well. (29:54)Dr. Boerman shares some ideas of what kind of experiments she'd like to conduct next to continue this line of research. (33:42)Panelists share their take-home thoughts. (35:29)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Guests: Dr. José Santos, University of Florida; Dr. Jeff Firkins, The Ohio State University; Dr. Bill Weiss, Professor Emeritus, The Ohio State University; Dr. Jimena Laporta, University of Wisconsin; Dr. Jim Aldrich, CSA Animal Nutrition; Dr. Tom Overton, Cornell University; Dr. Mark Hanigan, Virginia Tech University; Martin Bengtsson, Balchem; Dr. Barry Bradford, Michigan State University; Dr. Turner Swartz, South Dakota State University; Dr. Adam Lock, Michigan State University; Dr. Goeff Dahl, University of FloridaBalchem's Bourbon & Brainiacs event took place at the Frazier History Museum during the 2025 ADSA annual meetings in Louisville, Kentucky. This bonus episode features a rotating slate of guests throughout the entirety of the episode. The episode begins with guests talking about how many ADSA meetings they've attended and some of their favorite locations. Quebec City travel nightmares, side trips to the Grand Canyon, and university host sites with dorms featuring no air conditioning were highlighted. (0:08)The group talks about the impact scientific meetings have on graduate students and how important the social and networking aspects are in the development of students' careers. (9:44)Formative moments in your career can be forged at ADSA meetings. Learning to step back and talk about the big picture of your work can be pivotal. Other panelists share their experiences in making the final decision on where to attend graduate school based on their experiences at ADSA meetings. (19:48)Martin Bengtsson, Balchem's Executive Vice President,  CFO and Animal Nutrition and Health General Manager joins the panel. He talks about his background and Balchem's investment in animal nutrition research. He asks the panel what they'd like to see a company like Balchem do more of to have a bigger impact and be more helpful to the industry. (22:49)A new wave of guests arrive. Topics include coaching quiz bowl and dairy challenge teams, softball games, rooftop lawn bowling and how one can go from being an up-and-comer to being one of the big names at ADSA to being a retiree. (36:24)Panelists share some of the events at this year's ADSA meeting they're excited to attend, including a symposium about feed additives for methane inhibition in conjunction with the Journal of Dairy Science and an applied nutrition series geared toward field nutritionists. (42:06)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this episode of The Dairy Nutrition Blackbelt Podcast, Dr. Peter Erickson from the University of New Hampshire continues to explore the environmental and nutritional factors that influence colostrum yield and quality in dairy cows. He shares data on cold stress, niacin supplementation, and dry cow cooling, along with fresh insights into IgG, intestinal development, and calf outcomes. Listen now on all major platforms!"The calves that were born of dams that received niacin supplementation showed significantly greater feed efficiency during early growth stages."Meet the guest: Dr. Peter Erickson earned his Ph.D. in Dairy Science from the University of Illinois, with prior degrees in Animal Sciences from the University of Maine and the University of Massachusetts - Amherst. He serves as Professor of Dairy Management and Extension Dairy Specialist at the University of New Hampshire. His research focuses on calf and heifer nutrition, especially colostrum management.Click here to read the full research articles:Factors influencing colostrum production of multiparous Holstein and Jersey cowsCreating models for the prediction of colostrum quantity, quality, and immunoglobulin G yield in multiparous Jersey cows from performance in the previous lactation and environmental changesLiked this one? Don't stop now — Here's what we think you'll love!What will you learn: (00:00) Highlight(01:45) Introduction(02:10) Temperature vs photoperiod(04:40) Niacin and colostrum(06:42) Cooling and cow comfort(08:48) Colostrum testing tips(09:40) Colostrum quality insights(13:18) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Adisseo* Priority IAC* Kemin* Afimilk- Zinpro- Virtus Nutrition

This episode was recorded in Fort Wayne, Indiana, during the 2025 Tri-State Dairy Conference.Dr. Jaborek gives an overview of his presentation including sire selection, how beef on dairy crosses compare, feedlot performance, liver abscesses and red meat yield. (6:21)Beef sire availability and quality have changed over time with the development of selection indexes and selection criteria. Calving ease, growth, ribeye area,and quality grade are important traits. (10:03)The panel discusses if milk replacer feeding protocols differ for beef on dairy calves. More research in this area is needed. The group then talks about liver abscesses, including etiology, prevalence, and animal welfare and performance impacts. Dr. Jaborek notes calves with liver abscesses gain about 0.2 pounds per day less, on average. The panel believes understanding the impacts of diet differences (beef calves vs. the dairy model) in early life on rumen development would be a fruitful area of research.  (16:00)Dr. Jaborek talks about some of the differences in growth and performance among beef calves raised on their dam, beef embryos from Holstein recips raised in the dairy system, and beef-sired calves from Holstein and Jersey dams raised in the dairy system. The panel talks about why beef calves in the beef system are outperforming those raised in the dairy system, including milk composition differences between beef and dairy cows and milk quantity and availability. Free-choice robot milk replacer feeding systems might better mimic the beef system environment. (26:21)The panel then explores how beef on dairy calves are fed post-weaning. Dr. Jaborek notes they generally continue to be fed a high concentrate diet which may contribute to the liver abscess and digestive issues given the long timeframe of exposure to concentrates. The panel ponders if backgrounding calves on pasture for some length of time after weaning would be beneficial. The group also delves into how maintenance requirements might differ for beef on dairy crosses and if feedlot nutritionists are making adjustments for these calves. (30:45)Given the price of beef calves, would it be more profitable to put beef embryos into dairy cows instead of using beef semen to create a beef-dairy crossbred? Matt then asks if any dairy producers are retaining ownership of these calves past 1-3 days of age. The panel discusses risks and rewards of both questions. (34:29)The panel talks about corn processing and potential impacts on rumen health and liver abscesses. Dr. Jaborek cites a study where feeding more fiber in the form of corn silage did not increase cost of gain, but improved liver abscess reduction by 30 percentage points. (38:47)Dr. Jaborek talks about yield and quality differences in dairy-influenced carcasses and talks about his top priorities for research in the beef on dairy sector moving forward. (42:21)Panelists share their take-home thoughts. (46:26)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt. 

In this episode of The Dairy Nutrition Blackbelt Podcast, Dr. Peter Erickson from the University of New Hampshire shares practical strategies to improve colostrum yield and quality in dairy herds. He unpacks new research on environmental impacts, dry period length, and the physiological triggers influencing colostrum production. Listen now on all major platforms!"Even just how we feed that calf on day one can impact how much milk she makes two or three or four years down the road."Meet the guest: Dr. Peter Erickson earned his Ph.D. in Dairy Science from the University of Illinois, with prior degrees in Animal Sciences from the University of Maine and the University of Massachusetts - Amherst. He serves as Professor of Dairy Management and Extension Dairy Specialist at the University of New Hampshire. His research focuses on calf and heifer nutrition, especially colostrum management.Click here to read the full research articles:Factors influencing colostrum production of multiparous Holstein and Jersey cowsCreating models for the prediction of colostrum quantity, quality, and immunoglobulin G yield in multiparous Jersey cows from performance in the previous lactation and environmental changesLiked this one? Don't stop now — Here's what we think you'll love!What will you learn: (00:00) Highlight(01:27) Introduction(02:03) Guest background overview(03:34) Colostrum insights(05:57) Maximizing yield and quality(08:39) Effects of dry periods(09:24) Nutritional influence(10:28) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Afimilk* Adisseo* Priority IAC* Kemin- Zinpro- Virtus Nutrition

In the Real Science Exchange Legacy Series, we celebrate the pioneers who have shaped the dairy industry. In this episode, we honor Dr. Charlie Staples, a distinguished professor at the University of Florida, whose groundbreaking work in dairy nutrition and mentorship touched countless lives. From his 35 years of research mentoring 23 graduate students to earning the American Dairy Science Association's Fellow Award, Dr. Staple's legacy continues to inspire. Join us as we explore his contributions and enduring impact on our industry.Guests introduce themselves and how they knew Dr. Staples. (1:05)Dr. Grummer shares when he and Dr. Staples were applying and interviewing for university jobs in the same pool, and how they eventually landed jobs at universities where the other was not in the pool. (7:22)Drs. Santos, Grummer and Zenobi share about Dr. Staples' early life, his undergraduate and graduate career, and his family and faith. (10:42)Dr. Staples took a sabbatical at the University of Wisconsin in Dr. Grummer's lab. He shares a story about taking Charlie smelt fishing, where the tradition is the newbie has to bite the head off a smelt. (18:04)Dr. Zenobi and Dr. Santos talk about Dr. Staples as a teacher and mentor, giving examples of his caring nature and thorough teaching style. (22:30)Dr. Grummer and Dr. Santos give a broad overview of Dr. Staples' research career, including pioneering work in nutrition-reproduction interactions, fat supplementation and the separation of the energy effect and the fatty acid effect on reproductive performance, heat stress and choline supplementation. All panelists emphasized the collaborative and interdisciplinary nature of Dr. Staples' work. (27:52)Dr. Grummer shares about the fatty acid research he and Dr. Staples collaborated on during Charlie's sabbatical, as well as the choline research he worked on with Dr. Staples when Dr. Grummer worked for Balchem. The panelists talk about how Dr. Staples was not afraid to reach out to experts in other areas of expertise to ask questions and how thorough he was in literature searches. They talk about a symposium paper he presented summarizing 30-plus years of choline research. (36:12)The panelists talk more about the legacy Dr. Staples left behind - he was unassuming, humble, kind, collaborative and a man of principles. (44:14)Panelists share their take-home thoughts about Dr. Staples' dedication to dairy science, mentorship and innovation. (54:51)The University of Florida established the Charles R. Staples Lecture Endowment to support the Charles R. Staples Lectureship Series. Each year, an invited speaker gives a seminar and meets with graduate students. If you'd like to support the endowment, you can do so by visiting the UF/IFAS Animal Sciences giving web page: https://give.ifas.ufl.edu/animal-sciences-giving/Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Dr. Hristov gave a webinar titled “Histidine: a limiting amino acid for dairy cows” on March 4, 2025, and joins the podcast in this episode for a deeper dive into the topic. Panelists introduce themselves and give some background on their interest in histidine (00:52)Dr. Hristov gives an overview of his webinar presentation, touching on some of the first research projects that showed lower protein diets resulted in no change in plasma methionine, but a decrease in plasma histidine. When dietary protein decreases, the cow relies more on microbial protein to meet her needs. Histidine content is about 20% less than methionine content in microbial protein. He also notes there are some short-term reserves of histidine in the body, so short-term studies may not show a histidine deficiency when indeed there is one. (7:08)Matt gives some perspective as a consulting nutritionist about the importance of histidine in diet formulation for his clientele. He agrees with Dr. Hristov about the higher requirement for histidine compared to methionine, and he generally formulates diets with 1.1 times more histidine than methionine. (12:38)The panelists share their experiences with the responses observed from providing additional histidine to lactating cows, including milk and component yields and changes in dry matter intake and body condition. They also talk about how muscle loss can mask a histidine deficiency in the short term. (15:43)The panelists discuss the challenges in determining histidine requirements and finding reliable sources of highly bioavailable histidine. (24:04)Why is rumen-protected histidine not commercially available? Clay explains it is due to the high cost of histidine. There are no feed-grade sources, and using human-grade sources is cost-prohibitive. Dr. Hristov notes swine nutritionists are starting to pay more attention to histidine, which might bring the cost down if demand increases. Matt notes aquaculture is also interested in histidine. (33:58)Matt comments that increasing fat content can be problematic for cheese plants. He sees increasing milk protein yield may be the next frontier of dairy nutrition and histidine might play an important role. The panel discusses the role milk pricing has played in the increased fat content. (37:32)The panel discusses what other amino acids might be important in dairy nutrition as research continues. They also touch on methane mitigation and reducing methane intensity per unit of milk. (43:45)Panelists share their take-home thoughts. (54:31)View Dr. Hristov's webinar on this subject by visiting https://balchem.com/anh/podcasts-webinars/histidine-a-limiting-amino-acid-for-dairy-cows-2/Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Western Dairy Management Conference in Reno, Nevada.Dr. Cantor gives an overview of her presentation at the conference, focusing on data from accelerometers and robotic feeders to predict calf sickness. While the correlations are there and we know calves change activity, behavior and feeding behavior before they get sick, there is more work to be done before the technology is ready for wide implementation. When data from both accelerometers and robotic feeders were used, Dr. Cantor's group was able to find respiratory disease with a 96% accuracy six days before clinical symptoms. (2:36)Dr. James and Dr. Cantor discuss the use of robotic feeders in the industry and the under-utilization of data collected by the feeders. Dr. James shares observations from a farm he works with about heifers coming in to the milking herd who were raised on robotic feeders compared to those raised in calf hutches. (6:15)The panel discusses the accuracy, specificity and sensitivity of the predictions from monitoring technologies. They also touch on challenges around deciding what parameters to use to classify an animal experiencing the onset of clinical disease and how that will vary depending on the disease. They go on to share their experiences with training algorithms and how computer scientists have different goals than animal scientists with this type of technology. (11:17)Dr. James talks about how data collection and using data can be a hard sell on some calf ranches. The panel talks about some of the challenges they have seen with adoption of technology and recordkeeping on dairies of various sizes. (28:30)Dr. Giordano gives an overview of his presentation on using monitoring technology in fresh cows to predict disease. His group has worked with wearable sensors that monitor rumination time and physical activity. More recently, sensor companies have added eating behavior and body temperature. Variations in these parameters create a health alert to check on that particular animal. (39:08)He goes on to describe two extremes in dairy farms. One spends little time and effort on looking for sick cows, while the other puts a lot of time and effort into this task. He discusses how bringing technology to these two types of farms benefits them and what drawbacks there are, along with an economic analysis for each. (43:14)The panel discusses how implementing monitoring technologies require a change in management. Allowing animals the opportunity to express their natural behavior is critical to success. They also talk about how veterinarians view this technology and the target age for calves to best learn how to use a robotic feeder. (48:54)Panelists share their take-home thoughts. (57:11)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Western Dairy Management Conference in Reno, Nevada.Stan begins with an overview of the dairy checkoff since its inception in 1983. At that time, dairy farmers were producing 139 billion pounds of milk, but only 122 million pounds were being consumed. Dairy promotion has evolved to focus on research and education about nutrition, crisis management and even partnerships with Domino's, Taco Bell and McDonald's. (3:02)Stan and Marty detail some of the national and regional partnerships around dairy menu options. Walt notes that the grilled cheese burrito from Taco Bell is one of his son's favorite fast food meals. The panel discusses some of the strategy behind the Taco Bell partnership as well as marketing to Gen Z consumers about how dairy fits into mind and body wellness. (6:39)Walt comments the checkoff has done and is continuing to do a great job of being future-ready. He remembers a few years ago hearing about the gaming generation and partnerships with Mr. Beast and YouTube and embedding cows in Minecraft, and now his sons are playing Minecraft and gaming and are on YouTube. (13:43)Stan notes in 1995, exports were at 3%. That has now increased to 16-17%. Marty gives some examples of partnerships with the Dallas Cowboys and HEB stores in Mexico to promote dairy. (16:09)The panel discusses the US investments in processing, the “Dairy Renaissance”, research into dairy-as-medicine, and continued product innovations to meet consumer demands. (23:24)Marty and Stan detail the agreement between the Dairy Checkoff and Mayo Clinic investigating the role of whole milk foods in treating and preventing cardiovascular and metabolic disease. (34:04)Panelists share their take-home thoughts. (37:51)You can find more information about the dairy checkoff at https://www.dairycheckoff.com/Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Western Dairy Management Conference in Reno, Nevada.Dr. Lock begins with an overview of his presentation, discussing nutrition and genomics impacts on the speed of progress in milk fat production. He also talks about historic differences in milk fat production in Europe compared to the US. With the reduction in generation interval that genomics provides, a more complete understanding of rumen and mammary metabolism will continue to be imperative. How do we supply the nutrients she needs to meet her genetic potential? (3:34)Can we feed too much 16:0? The panel discusses how palmitic and other fatty acids are incorporated into milk fat. They emphasize that no matter what, milk fat will remain a liquid at body temperature, so that does provide some limitations. Processors can alter their protocols to account for increased palmitic acid in milk fat and for increased milk fat in milk overall. (8:35)There is a gene called DGAT that can explain about 50% of the variation in milk fat content. Dr. Lock discusses some research looking at more vs less favorable DGAT profiles and how feeding palmitic acid interacted with those profiles in milk fat production. (13:04)The panel discusses whether there is a physiological limit for how much milk fat a cow can produce. Traditionally, when milk yield increased, fat yield decreased, but that is not the current case. We are learning more all the time about altering rations and using new oilseed ingredients like whole cottonseed and high-oleic soybeans. Dr. De Souza emphasizes that understanding de novo fatty acid synthesis is really important to keep pace with genomic progress. (16:08)Amino acid supplementation has recently been linked with milk fat production, with the assumed mechanism of action being increased mammary gland enzyme synthesis and activity. Dr. Lock describes a study assessing amino acid-fatty acid interactions in fresh cows. The amino acid (metabolizable protein) effect was greater for fat yield than feeding fatty acids, which was interesting. But perhaps more exciting was the effects were additive. Feeding both high metabolizable protein and 2% palmitic:oleic acid blend resulted in 9.5 kg more energy-corrected milk and a carryover effect after supplementation ceased. (22:41)Dr. Lock summarizes some of his group's work on using oilseeds in dairy diets.(28:24)Dr. De Souza and Dr. Lock give some perspective on just how much we have learned about milk components over the last several years. (34:38)Panelists share their take-home thoughts, including practical advice on increasing milk fat production and what's on the horizon for fatty acid nutrition research. (37:15)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Western Dairy Management Conference in Reno, Nevada.Dr. Kononoff begins with some renewable fuels history. Since the renewable fuels standard in 2007, corn production for ethanol has increased to around 50% of the crop going to ethanol production. With the subsequent increase in fuel has come an increase in distillers grains and the industry has learned how to use them to feed cattle better. Later, the government created additional policy for next-stage renewable fuels, which has spurred biodiesel production. Currently, just under 50% of the soybean crop goes to fuel production. Soybean meal availability has increased and costs have decreased over the past few years. Most of the soybean oil is solvent-extracted.   (5:57)Dr. Lock talks about increased acres of high-oleic soybeans in dairy-soybean crossover states. He summarizes some of the work his group has done on feeding high-oleic roasted whole soybeans as a replacement for soybean meal in the diet, citing the benefits of the oil in the diet as well as increased bypass protein. (15:41)The panel discusses whether canola meal, which is fairly high in oleic acid, would show similar benefits to feeding whole roasted soybeans. They also talk about how tariffs may or may not impact canola meal and canola oil prices. (24:26)Over time, the dairy industry has moved away from alfalfa as a protein source and toward soybean meal. The panel discusses the pros and cons of this change. (26:46)Dr. Kononoff gives his perspective on just how much soybean meal can be fed in dairy cow diets. Nitrogen excretion is an important consideration. He reminds the audience that renewable fuels policy is the reason behind many of the feed ingredient changes we've observed in the past 15-20 years, and that policy can change very rapidly. He emphasizes the industry needs to remain nimble and prepared to adapt. The panel also touches on pricing of feed ingredients in different parts of the country and how distillers grains are currently used in dairy diets. (31:08)Panelists share their take-home thoughts. (40:49)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Florida Ruminant Nutrition Symposium. Dr. Bach gives an overview of his presentation, highlighting that buffers make the rumen resistant to a decrease in pH while alkalizers immediately increase rumen pH. He prefers magnesium oxide, an alkalizer, over sodium bicarbonate, a buffer. Both are effective, but sodium bicarbonate requires a larger amount, thus taking up more room in the diet. The magnesium oxide must be of high quality and soluble in the rumen. (3:40)Dr. Richards asks if we should use magnesium oxide more as a first line of defense against acidosis. Dr. Bach notes that the very best strategy is to avoid using either additive by making a proper ration balanced in terms of amount and rate of degradation of starch. But there are many constraints in the field, so he recommends using magnesium oxide before sodium bicarbonate. For the magnesium oxide to be effective, it must be solubilized in the rumen to magnesium hydroxide, and solubility can be tested in a variety of ways to determine quality. (7:35)The panel discusses the impact of magnesium oxide in place of sodium bicarbonate on DCAD and which DCAD equation(s) should be used for calculations. Dr. Bach recommends removing sodium bicarbonate from rations containing less than 1% of the ingredient. It will have little effect on the rumen, but make room in the ration. The panel explores how this can impact farm-level economics. (12:39)Dr. Bach also mentions probiotics and their impact on rumen function. In vitro studies have shown a wide variety of modes of action and positive results. Extrapolating in vitro doses to the cow often results in unsustainable amounts of the additive needing to be fed. Applied studies at the cow level have yielded inconsistent results. (23:29)Scott asks how long Dr. Bach has been making the case for pulling sodium bicarbonate out and putting magnesium oxide in, and what kind of pushback he has received. Dr. Bach gives some of the reasons farmers have given for not wanting to make this management change. He also notes that farmers who do make the switch do not tend to go back to sodium bicarbonate. (25:18)Dr. Bach and Maimie discuss grass silage diets and grazing diets with high amounts of moisture and how best to combat acidosis symptoms with those. In diets like this, where you're not trying to make room for energy, sodium bicarbonate can be a good choice. Dr. Richards chimes in with questions about the ratio of the two ingredients; Dr. Bach indicates the ratio doesn't mean much to him. (26:16)Panelists share their take-home thoughts. (33:27)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Florida Ruminant Nutrition Symposium. Microbial protein has always been Dr. Frikins' main interest. It's the most important and consistent source of protein for the cow, with a very high amino acid content. Histidine is the only exception, but bypass protein sources high in histidine complement microbial protein well. Our assessment of microbial protein is all based on prediction models. In his presentation, Dr. Firkins talked about what we can do to have consistently high microbial protein production and how to make the best use of the models. He touched on starch and fat content as two areas of focus, emphasizing a balanced diet to achieve a balanced supply of microbial protein. (5:36)Dr. Firkins notes that about 90% of the bacteria in the rumen can't be cultured, and there is great diversity in the rumen. There's a core group of bacteria that almost every cow has that are really good at their job because they've been co-selected along with the cow for fiber digestion. The panel discusses how much the microbiome changes over time, host interactions with the microbial population, and inoculation of calves at birth and weaning. (8:47)Dr. De Souza and Dr. Faciola talk about starch associative effects and their impacts on fiber digestibility, how sugars impact the rumen and butyrate production, and the importance of butyrate in de novo milk fat synthesis. Dr. Frikins hypothesizes that when sugars improve fiber digestibility, the sugar stimulates how fiber digesters do their job. Some studies have shown an increase in rumen pH when sugars are supplemented, which may be part of the mechanism of improved fiber digestibility. However, he doesn't recommend using sugars when there is a lot of starch in the diet. (13:38)Dr. Faciola and Dr. Firkins discuss some of the finer points of the dietary starch and fiber digestibility relationship. What are you replacing when you add more starch? What is the proper amount of effective fiber in higher-starch diets? On the other hand, if you decrease starch a little bit, there might be more room for fat. Well-managed cows with adequate effective fiber can probably handle more starch. Dr. Firkins underlines that starch is more digestible than fiber and thus supports microbial protein, but an optimum level is desirable, perhaps 28-20%. (20:37)The panel talks about microbial growth efficiency and the energy-spilling mechanisms some bacteria have. Some models suggest that starch-digesting bacteria have higher maintenance energy requirements. The group then pivots to methane production and available feed additives marketed to reduce methane. Dr. Firkins notes that there is quite a bit of variability in the additives. He emphasizes that if we're using these products, we need to know and measure what's in them and have them be consistent. This is challenging due not only to variability in product, but also rumen adaptation. Dr. Firkins also reminds the audience that improving the cow's efficiency in general in a variety of ways will lead to a smaller environmental footprint. This can range from improving reproductive efficiency to understanding differences in the microbiome of cows who emit more or less methane and trying to shift microbial populations to those with lower emissions. (23:12)Dr. De Souza and Dr. Firkins discuss fatty acid supplementation and fiber digestion relationships. Dr. Firkins explains that in the microbiology literature, it's common to culture bacteria in a simple or complex medium, then add yeast culture. Interestingly, the yeast culture contains a lot of palmitic acid, which has been shown to improve fiber digestibility. He suggests the cell membrane of the bacteria is very critical. When fat supplementation depresses fiber digestibility, he suspects it's disrupting the bacterial membrane. Dr. De Souza recommends 1-2% palmitic acid in the diet for optimal results. (33:58)The panel touches on the importance and relevance of in vitro fermentation work, why histidine is the limiting amino acid in microbial protein, and Dr. Firkins' passion for protozoa. (43:08)Panelists share their take-home thoughts. (53:40)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this episode of the AgCulture Podcast, Steve Sweet brings his decades of experience in dairy management and agribusiness to explore the evolving relationship between dealers, manufacturers, and dairy farmers. He shares practical insights on navigating automation, tech integration, and staffing challenges across dealer networks. Learn how changing farm sizes, technology demands, and market expectations are reshaping agribusiness strategy. Listen now on all major platforms!Meet the guest: Steve Sweet holds a B.S. in Dairy Science from Cal Poly, San Luis Obispo, and a Dairy Management degree from Michigan State University. With over 20 years of industry experience, his work spans dairy nutrition, farm management, and robotic milking systems across North America.What you will learn: (00:00) Introduction(04:04) Dealer network evolution(05:10) Data in dairy tech(06:27) Staffing and education shifts(08:21) Manufacturer-dealer tensions(12:57) Global market contrasts(32:01) Closing thoughtsDiscover the world of agriculture with the "Ag Culture Podcast".  This podcast will be a gateway for those passionate about agriculture to explore its global perspectives and innovative practices.Join Paul as he shares his experiences in the agricultural industry, his travels and encounters with important figures around the world.Available on YouTube, Spotify and Apple Podcasts.Subscribe at ⁠⁠⁠⁠⁠⁠http://www.agculturepodcast.com⁠⁠⁠⁠⁠⁠ and keep an eye out for future episodes, bringing insights and stories from the vibrant world of agriculture.

This episode was recorded in Reno, Nevada, during the 2025 Western Dairy Management Conference. Dr. Hemme begins with a demonstration of three different-sized glasses of milk representing the daily average dairy consumption in China, Europe, and the world as a whole. He explains that when you make predictions, it's good to identify the two main drivers of uncertainty in your industry. In the case of dairy, he cites whether or not people like dairy and whether or not they can afford it. He goes on to describe the four scenarios that can be created from those main drivers: people like dairy and can afford it, people don't like dairy but could afford it, people like dairy but can't afford it, and people don't like dairy and can't afford it.  (4:05)Walt asks Dr. Hemme to give some perspective on what makes a country a reliable exporter built for the global economy. He gives a unique example of how American football versus soccer compares to exporting dairy from the US to the global market. Matt chimes in with his perspective on how DFA is positioning the industry for exports. He notes that we live in the world of VUCA - volatility, uncertainty, complexity, and ambiguity - and that we have a lot of VUCA happening in the US right now. In general, he's very bullish on our natural resources, management skills, and technical capability in the US dairy industry.  (10:17)The panel discusses who in the world is going to be able to meet the building demand for dairy products, and what the US might need to do to be a major player - in essence, moving from playing football to playing soccer. Dr. Hemme gives culture, policy, and relationship building as potential challenges for the US. (16:37)Matt is encouraged by the new investments in processing plants in the US and looks for a “build it and we will grow into it” scenario as we move forward. Dr. Hemme agrees that the processors are on board. But he wonders about the dairy farm side - no growth in cow numbers, not much growth in production, and breeding so many cows with beef semen makes him think the US is not believing in a growing dairy industry. He also talks about changing interest rates over time and impact on capital management. (25:50)The panel discusses the US milk price compared to the world milk price, the cost of production, and exchange rates. (29:45)Matt gives some perspective on beef-on-dairy. As the beef cycle levels back out and more beef heifers are retained, he forecasts fewer dairy cows being bred to beef semen and an increase in the supply and retention of dairy heifers. (34:31)Dr. Hemme talks about dairy demand and global population growth trends and predictions. (39:38)Panelists share their take-home thoughts. (42:02)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this second part of The Dairy Nutrition Blackbelt Podcast episode with Dr. Claira Seely, from the University of New Hampshire, she discusses identifying metabolic disorders and diagnosing subclinical hypocalcemia in dairy cows. She also highlights effective prevention strategies, focusing on key nutritional approaches like negative DCAD rations and the use of calcium binders. Listen now on all major platforms!"Low blood calcium at four days in milk will give you a better idea of what percent of your herd is experiencing a calcium issue."Meet the guest: Dr. Claira Seely is an Assistant Professor of Precision Dairy Management at the University of New Hampshire. With a PhD in Dairy Science from Cornell University, Dr. Seely's research focuses on transition cow biology and precision technology integration.Click here to read the full research articles:The association of subclinical hypocalcemia at 4 days in milk with reproductive outcomes in multiparous Holstein cowsAssociation of transient, persistent, or delayed subclinical hypocalcemia with early lactation disease, removal, and milk yield in Holstein cowsAssociation of subclinical hypocalcemia dynamics with dry matter intake, milk yield, and blood minerals during the periparturient periodWhat will you learn: (00:00) Highlight(01:32) Introduction(01:19) Diagnosing subclinical hypocalcemia(02:16) Prevention strategies(03:25) Negative DCAD and zeolite(04:54) Oral boluses(05:46) Delayed bolus administration(08:06) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Adisseo- Afimilk- Kemin- Virtus Nutrition- Zinpro- Volac

In this episode of The Dairy Nutrition Blackbelt Podcast, Dr. Claira Seely, from the University of New Hampshire, sheds light on the evolving understanding of subclinical hypocalcemia in dairy cattle. Dr. Seely explains how the understanding of this condition has evolved over time, especially in diagnosing it at the right moment. Learn how the timing of calcium monitoring can impact milk production, reproduction, and overall cow health. Listen now on all major platforms!"Cows with low blood calcium at four days in milk produced significantly less milk and had lower reproductive success."Meet the guest: Dr. Claira Seely is an Assistant Professor of Precision Dairy Management at the University of New Hampshire. With a PhD in Dairy Science from Cornell University, Dr. Seely's research focuses on transition cow biology and precision technology integration.Click here to read the full research articles:The association of subclinical hypocalcemia at 4 days in milk with reproductive outcomes in multiparous Holstein cowsAssociation of transient, persistent, or delayed subclinical hypocalcemia with early lactation disease, removal, and milk yield in Holstein cowsAssociation of subclinical hypocalcemia dynamics with dry matter intake, milk yield, and blood minerals during the periparturient periodWhat will you learn: (00:00) Highlight(01:21) Introduction(01:03) Guest background(02:59) Hypocalcemia insights(04:16) Diagnosis timing for hypocalcemia(05:26) Blood calcium dynamics(07:49) Reproductive and intake effects(09:05) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Adisseo- Zinpro- Volac- Afimilk- Kemin- Virtus Nutrition

This episode was recorded in Reno, Nevada, during the 2025 Western Dairy Management Conference. The panel discusses their individual experiences with outbreaks in different states. Beth talks about her group's microbial surveillance technology they used to compare rectal swabs from positive and non-positive herds. They noted elevations in specific virulent E. coli, Salmonella spp., and Clostridium perfringens in the HPAI-positive herds. Enrique noted that in California, the outbreak began in the South Valley during periods of heat stress, which exacerbated symptoms. He also felt that some dairies panicked a little and moved cows too much, which did not help. In the North Valley, the outbreak happened in cooler weather, and dairies purposefully did not move cows out of their pens and provided supportive therapy within the pen. (5:25)Dr. Schcolnik emphasized making sure i's are dotted and t's are crossed in your nutrition program to help manage through an outbreak. The immune system is an obligate glucose utilizer, so energy is key, as are protein and trace minerals. He noted they also added binders to diets, and either probiotics or double doses of yeast to keep the rumen healthy. Decreasing intake is a big symptom, so he recommends vitamin B supplementation to stimulate appetite. (12:30)The panel discusses how the Texas and California outbreaks differed from one another, including heat stress, recovery in milk production after infection, bird migration and cattle movement. Enrique notes that in California, it seemed like transmission was going downwind. Animal movement, wild birds and milk trucks were also implicated. (14:31)Several companies are investing in vaccine development, but the virus mutation is a challenge. Dr. Spencer wonders if the vaccine will end up resembling the human flu vaccine where you hope to target the general structure of the virus to reduce impact. The panel talks about natural immunity and how cows will be impacted in the lactation after they were ill. Dr. Schcolnik has observed that a percentage of cows who were dry during the outbreak aren't performing as well after freshening. He hypothesizes this could be due to mammary cell death during infection, as the virus lyses the cell as it exits the cell. (24:41)The panel discusses practical recommendations for dairy producers to prepare for or help mitigate during an outbreak. Biosecurity is key. Vaccines are hopefully on the way, but until then, minimizing cattle movements within the herd, post-dipping cows as soon as possible after the machine falls off and minimizing splashing of milk are all good practices. The panel looks forward to more research about all the different ways the virus transmits. They're also eager to learn more about treatment plans and what has worked for different dairies regarding giving fluids, altering rations, boosting the immune system, managing co-infections and impacts on calves and heifers. (29:18)Lastly, panelists share their take-home thoughts. (37:33)Scott invites the audience to Bourbon and Brainiacs at ADSA in Louisville - a bourbon tasting with all your favorite professors! Sign up here: https://balchem.com/anh/bourbon/Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Tune in as the dairy team catches up with recent graduates of the Dairy Science Club at Iowa State!

This episode was recorded in Fort Wayne, Indiana, during the 2025 Tri-State Dairy Conference. Dr. Grant gives an overview of his presentation at the conference, highlighting cow time budgets and the importance of natural cow behavior to health, welfare and productivity. The impacts of overcrowding, including rumen pH and de novo fatty acid synthesis, are a key component of his message. (7:07)Eating, resting and ruminating are the big three behaviors we've studied for decades. In addition to their obvious importance to cow welfare, they have a real health and performance effect. Dr. Grant suggests the recumbent rumination - just lying down and chewing her cud - is really the cow's superpower. Cows with the same rumination time who accomplish more while lying down have less subacute ruminal acidosis, greater dry matter intake, and higher fat and protein content in their milk. It all boils down to the balance between eating time and recumbent rumination time. (12:15)The panel discusses the definition of overcrowding. Spoiler alert: it depends. (15:50)Clay asks Rick if overcrowding of beds or feed bunks is more important. The easy answer is both, but Rick acknowledges he'd say beds if he were pushed for an answer. Resting is a yes or no; she's either lying down or she's not. From the feed bunk perspective, a cow can alter her behavior to a point for adjusting to overcrowding - eat faster, change her meal patterns, etc. A hungry cow will walk by the feed to recoup lost rest time. Cows should be comfortable enough to spend at least 90% of their rumination time lying down. (17:50)Dr. Grant thinks of overcrowding as a subclinical stressor. A cow has different “accounts” for different activities: lactation, health, reproduction, etc., as well as a reserve account. To combat the subclinical stress of overcrowding, a cow uses her reserve account, but that's hard to measure. If the reserve account gets depleted and another stressor comes along, the overcrowded pens are going to show greater impacts. The panel brainstormed ideas for how to better measure a cow's reserve account. (19:39)Clays asks if overcrowding is affecting culling rates. The panel assumes it has to be, though no one can point to a study. Dr. Grant notes there is data from France that shows decreased longevity in cows who don't get enough rest, which is a hallmark of overcrowding. Given the low heifer inventory, the panel muses if the industry ought to pay more attention to the culling impacts of overcrowding and have a more dynamic approach to evaluating stocking density as market and farm conditions shift. (25:10)Bill asks about nutritional and management strategies to reduce the stress of overcrowding. Rick notes that overcrowding tends to make the rumen a bit more touchy, so he talks about formulating diets with appropriate amounts of physically effective fiber, undigested NDF, rumen-fermentable starch, and particle size. (29:21)Dr. Grant talks about the differences in rumination when a cow is lying down versus standing. The panel discusses cow comfort, preferred stalls, and first-calf heifer behavior in mixed-age groups with and without overcrowding. Bill and Rick agree that having a separate pen for first-calf heifers on overcrowded farms would benefit those heifers. Dr. Michael comments on evaluating air flow and venting on-farm. (33:49)The panel wraps up the episode with their take-home thoughts. (47:55)Scott invites the audience to Bourbon and Brainiacs at ADSA in Louisville - a bourbon tasting with all your favorite professors! Sign up here: https://balchem.com/anh/bourbon/ (52:02)The paper referenced in this conversation from Dr. Bach can be found here: https://www.sciencedirect.com/science/article/pii/S0022030208711226Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded in Reno, Nevada for the 2025 Western Dairy Management Conference. Dr. Shabtai gives an overview of her presentation. Afimilk has a new technology that includes a feed efficiency sensor to determine eating, rumination, heat stress monitoring and more. The Feed Efficiency Service combined with the AfiCollar can estimate dry matter intake, which, when combined with Afimilk's milk meter data, yields an efficiency value of milk income over feed cost for each cow. She details how the algorithm works to predict intake and some of the challenges faced during the development of this technology. The algorithm was developed with Holsteins, but a Jersey algorithm is nearing completion. (5:33)Shane and Emily share some of their experiences with beta-testing the Feed Efficiency technology on-farm to evaluate, including animal-to-animal variation and variation in different stages of lactation. The panel discusses how genomics could pair with this data to aid in selection decisions. (9:21)Walt asks Dr. Shabtai to share how the company took the technology from research facilities to commercial farms, and asks Shane and Emily to share how the technology has proven itself on-farm. (13:11)Shane notes that they've had a handle on the milk side of the efficiency equation of individual cows for a while, but they didn't know much about the feed intake side of the equation. This technology allows for that. Shane also shares how this technology adds another tool to their dairy's sustainability toolbox.  (18:50)Walt asks both producers to share a metric that they thought was important before, but now that we have more knowledge and technology, it might not be as important as they thought. Shane's pick is starch level in corn silage, and Emily's is percent pregnant by 150 days in milk. (21:18)Dr. Shabtai shares the basics that a producer would need to implement this technology. She details a few things that have changed and will change about the product based on data from beta testing and notes there are always new things to see and find on-farm. (22:59)Scott asks Shane and Emily what metric they'd like to measure that they can't measure yet. Shane wonders if there would be a way for AI to compile weather and market data to assist with milk or feedstuff contracting decisions. Emily would like to be able to use more on-farm technology to help manage people. She shares how the data she has now allows her to see different improvements that could be implemented for different milking shifts. Shane talks about need-to-know information versus neat-to-know information. (26:35)The panel discusses how the technology is updated through software rather than hardware when new versions are available. They also share some tips for implementing the software on-farm. Walt asks each panelist their “I wonder if…” question. (29:58)The panel wraps up with their take-home thoughts, and Dr. Shabtai shares where farmers can learn more about Afimilk's feed efficiency technology by visiting afimilk.com. (36:49)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Western Dairy Management Conference in Reno, Nevada. Dr. Sabine Mann, Cornell University; Dr. Will Mustas, Progressive Dairy Solutions; Dr. Don Niles, Dairy Dreams LLC; and Joey Airosa, Airosa Dairy Farms, introduce themselves. (0:48)Dr. Mann outlines the high points of her presentation. Giving an adequate amount of high-quality colostrum quickly after birth is essential to equip the calf with the best chances to stay healthy. Colostrum is more than a solution of water and immunoglobulins, and we are continuing to learn more about other nutrients and growth factors that colostrum contains. (12:03)Dr. Niles and Mr. Airosa talk about colostrum and maternity protocols on their dairies. Each has dedicated maternity staff in charge of postnatal calf care. Don mentions they often have public tours of their dairy and shares some anecdotes. Joey's maternity staff try to get colostrum in calves within 30 minutes of birth and have worked out a good communication system to ensure seamless calf care when shift changes occur. (13:57)Dr. Mann emphasizes the timing of colostrum delivery is critical. But what about the amount? Should every calf get four liters? Joey notes they bottle feed and have settled on three quarts for Holstein calves and two quarts for Jersey calves. Sabine says research backs that up - calves will not voluntarily drink much more than 3-3.5 liters. Using esophageal feeders to give four liters could be overfeeding in some cases, which could cause slower emptying of the stomach and thus slower arrival and uptake of immunoglobulins at the small intestine. The four liter recommendation came from the idea that good quality colostrum probably had about 50 grams per liter of IgG, and at that time, we wanted to get 200 grams into the calf. Perhaps making a sheet with recommended amounts based on calf weights could be helpful for maternity staff.  Dr. Mann also clarifies that the 50 grams per liter of IgG is not really good quality colostrum. Most herds average about 90-100 grams per liter of IgG in colostrum. She recommends every farm find out how good their colostrum is and optimize feeding amounts from there. (22:45)Dr. Mann notes the importance of making sure dry cows are not deficient in protein supply and ensuring the dry period is long enough to create high-quality colostrum. While it's commonly thought older cows have better colostrum than young cows, she underlines again the importance of measuring colostrum quality to know for sure. She also highly recommends measuring colostrum quality from individual cows before pooling so that poor colostrum does not dilute good colostrum. (31:04)Dr. Mustas shares some of the challenges he's seeing on dairies where he consults. What can we do to control the bacteriological quality of colostrum? He notes there's no reason we can't get very low bacteria counts pre-pasteurization. Making sure maternity areas are clean and sanitary, udders are prepped very well, and harvesting equipment is not neglected are all great strategies. (35:53)Dr. Mann talks about individual cow variation in colostrum production and some factors that might influence including placental interactions, hormones, and genetics. (38:04)Scott and Sabine discuss some of the research around supplementing with choline during the dry period and subsequent colostrum production. (41:28)Dr. Niles comments that pasteurization of colostrum has been one of the most exciting technologies to come along. On his farm, the pasteurizer has given them much more control over colostrum quality and delivery time. Dr. Mann agrees storage of colostrum has given dairies the ability to be strategic about how they use colostrum, what colostrum they use, and to also plan for seasonal colostrum shortages. She agrees with Dr. Mustas that clean colostrum harvesting equipment is key to low bacterial counts. (44:13)Dr. Mustas talks about how the beef-on-dairy phenomenon has altered colostrum protocols. Calf ranches are giving deductions for poor colostrum scores when calves are received. Some operations even offer premiums or discounts on daily yardage depending on individual calf colostrum scores. (50:21)Joey, Don, and Sabine comment on the importance of finding the right people to work in maternity and instilling the idea that taking care of cows and calves is both a great responsibility and a great honor. (52:56)The panel wraps up with their take-home thoughts. (58:31)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This episode was recorded at the 2025 Western Dairy Management Conference in Reno, Nevada. Gregg Doud, National Milk Producers Federation, begins with an overview of his talk regarding recent and ongoing investments in the dairy industry. Dan Siemers, Siemers Holsteins, notes they were able to build a new dairy and find a new milk market because Agropur built a new plant in their area. Corey Geiger, CoBank, describes that the US is approaching $9 billion of new investment in dairy plants coming online through 2027, over half of that in cheese. High-quality whey protein isolates are in equal demand as cheese, so that has been a large part of the investment as well. He mentions investment in class one beverage milk and extended shelf life, as well as growth in yogurt and Greek yogurt. The panel also discusses milk in schools.  (1:35)Corey talks about the generational change on dairy farms regarding components. Dan mentions that in one generation, you can increase the fat percentage by 0.4 using bulls available today. The focus on pounds of fat and protein plus health traits has resulted in somewhat less milk. Dan feels that the industry needs to focus a bit more on pounds of milk as a carrier to get protein back in the business. Some plants indicate there might almost be too much fat, so a focus on protein pounds may be in order. (11:03)Corey states that 92% of dairy farmers get paid on multiple component pricing, and 90% of that milk check is butter fat and protein. While some cheese plants don't quite need all the butter fat that's coming from dairy farms, it's important to note that we are still not filling our butter fat needs domestically. There are definitely opportunities in the butter sector. The panel discusses some shuffling in domestic processing might also be needed to better use the sweet cream that's available. (13:01)Scott asks about export markets in developing countries. Gregg mentions that many Central American dairy products contain vegetable oil, so there is a lot of potential there. Corey agrees and states there is also similar potential in the Middle East and North Africa. He also notes that lack of refrigeration is still an issue in some parts of the world, so shelf-stable products are critical. Gregg mentions that drinkable yogurts are in demand in Latin America. (18:29)The panel dives into the way beef on dairy has changed the industry. Dan notes the baby calf market has been a huge profit center, where the dairy can essentially break even and the calves provide the profit. This may be creating a challenge where a lot of dairies aren't creating enough replacement dairy heifers. (23:16)Data and how we use it is the next topic the group discusses. Gregg shares a story of an MIT grad who is developing an artificial intelligence algorithm to combine cow genetics with different diet ingredients and feed additives to decrease methane production while improving cow productivity. (28:49)The panelists close out the episode with their take-home messages. Corey gives listeners a look at the impact of the domestic dairy market. Dan shares the sustainability story and climate impact of the dairy industry will continue to be important. Gregg is excited about new technologies, but asks for assistance in working with the federal government to get those technologies approved at the speed of commerce. The panel also discusses the impacts of tariffs on agriculture and how dairy farmers need to be communicating with their members of Congress. (32:56)Please reach out to your Congress members. Start the conversation, and  help them understand!Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This Real Science Exchange podcast episode was recorded during a webinar from Balchem's Real Science Lecture Series. You can find it at balchem.com/realscience. Dr. Santos begins with a timeline of events that occur during the cow's transition from the dry period to her exit from the fresh pen. He suggests that cows should be dried off at around 230 days of gestation, then moved to a closeup group at 250-255 days gestation which is around three to three-and-a-half weeks before calving. Dr. Santos recommends keeping multiparous cows separate from primiparous cows and feeding to minimize metabolic disorders in early lactation. After calving, cow health needs to be monitored for early detection and treatment of disease. In addition, diets that do not limit voluntary dry matter intake should be fed. During the early postpartum period, controlling excessive weight loss and lipid mobilization is the goal.  (00:27) What is the association between time spent in the closeup pen and disease? Research shows that around three to four weeks in the prepartum group is associated with the lowest risk of morbidity, maximum milk yield and highest pregnancy rates. How does a change in body condition during the first 65 days in milk impact cyclicity? How does 90-day milk yield impact cyclicity? Cows that lose one or more units of condition are less likely to be cyclic at the end of the voluntary waiting period. There is a small statically positive association between milk yield and cyclicity. Dr. Santos' first take-home message is to avoid excessive body condition loss after calving. Cows should lose no more than 0.5 body condition units from the week before calving to the first AI. This can be accomplished by minimizing over-conditioned cows at dry-off and reducing the risk of disease in early lactation.  (6:13) What about feed efficiency? Dr. Santos describes experiments comparing the 25% most efficient to the 25% least efficient cows. All cows produced the same amount of energy-corrected milk, but the most efficient cows ate four kilograms less feed each day. The risk of morbidity and the culling rate was the same for both groups, as was reproductive performance. Dr. Santos suggests we should not be afraid of selecting for feed efficiency while still optimizing intake in early lactation.  (18:23) Morbidity negatively impacts intake in early lactation. Around one-third of cows are affected by disease in the first three weeks of lactation and almost 80% of the first disease diagnoses occur during the first three weeks postpartum. The earlier in lactation disease occurs, the longer the legacy effects from that disease can impact cow health and performance. Dr. Santos describes an experiment in beef cattle evaluating how an inflammatory response impacts nutrient partitioning away from performance. Early lactation morbidity not only makes a cow not want to eat, it also may shift nutrients away from production toward survival, resulting in fewer nutrients available for milk production and reproduction. Dr. Santos describes a series of experiments evaluating the impact of early lactation disease diagnosis on reproductive performance. Dr. Santos' second take-home message is to stimulate dry matter intake and minimize disease in the early lactation period. (22:21) How can we formulate diets that will improve reproduction? First, we should formulate diets that reduce the risk of disease. Then we should incorporate nutrients that are known to improve reproduction in cows. Dr. Santos describes how supplementation with rumen-protected choline decreases triglyceride accumulation in the liver and improves milk yield. He also details the mechanisms of using acidogenic diets to reduce hypocalcemia. He recommends not using these diets for heifers and feeding them for around 21 days to cows rather than the entire dry period. Dr. Santos feels that forage quality has been neglected in the transition period and details how improved fiber digestibility during the transition period can have longer-term impacts. Lastly, he recommends feeding 1-1.5% supplemental fat in early lactation diets for improved reproduction and milk yield without negative impacts on body condition. In closing, Dr. Santos presents a summary of diet formulation recommendations for transition cows.  (34:13) Dr. Santos leads an engaged question-and-answer session with the webinar audience. (51:11) Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.   If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt. 

In this episode, we honor and celebrate the remarkable career and contributions of Dr. Jim Drackley from the University of Illinois, a pioneer in dairy science and animal nutrition. Jim's work has reshaped our understanding of dairy cow health, metabolism and nutrition. Dr. Cardoso, Dr. Overton, and co-host Dr. Jeff Elliott are former coworkers or graduate students of Dr. Drackley's. (0:11)Dr. Drackley begins by telling the audience about his background and how he became a dairy scientist. He talks about several of his mentors during his schooling. (9:20)Speaking of mentors, Scott asks Dr. Elliot, Dr. Overton, and Dr. Cardoso to describe Dr. Drackley's mentorship of them during teaching, graduate school and beyond. They praise Jim's thoughtfulness and hands-off approach that taught them to think critically. (14:06)When it comes to major contributions to the industry, Dr. Drackley names two that he is most proud of: expanding the knowledge of controlled energy dry cow programs using straw and corn silage to help control energy intake and his work in baby calf nutrition, specifically feeding more milk on-farm to calves. Dr. Overton adds that a visionary paper Dr. Drackley wrote in the late 1990s where he referred to the transition period as the final frontier as another important contribution. Dr. Cardoso also emphasizes Dr. Drackley's excellent teaching skills as another achievement of note. (20:58)Dr. Drackley says the teaching part of the job was the part that scared him the most when he started. Graduate school offers little formal teaching training and experience so one learns on the job. Jim describes his teaching style as organized, and he liked teaching in an outline fashion, working from the main topic down through the details. He worked hard to get to know the students, learn their names as soon as possible, and be approachable and empathetic. Later in his career, he used a flipped classroom approach for a lactation biology course and enjoyed it. (28:45)The panel then reminisces about how much technology has changed from a teaching perspective as well as statistical analysis. Lecturing has moved from chalkboard to overhead projector to slide carousel to PowerPoint. Statistical analysis has moved from punch cards or sending data to a mainframe computer to performing real-time statistical analysis on your computer at your desk. (33:00)Jeff, Phil, and Tom share stories and memories of their time with Jim. (37:30)Scott asks Jim what challenges will need to be tackled in the future in the dairy industry. He lists environmental aspects (nitrogen, phosphorus, and greenhouse gases), increasing economic pressure on farms, and improving forage production and efficiency of nutrient use. Dr. Drackley's advice for young researchers is to carve out a niche for yourself. (47:40)Dr. Elliott, Dr. Overton, and Dr. Cardoso share some final thoughts paying tribute to Dr. Drackley and his accomplished career. (1:06:18)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This Real Science Exchange podcast episode was recorded during a webinar from Balchem's Real Science Lecture Series. You can find it at balchem.com/realscience.How can we increase milk protein and capture that income opportunity? Dr. Van Amburgh describes the seasonal drop in milk protein observed in the summer months. Heat stress may play a role in altering insulin sensitivity and how the cow partitions nutrients. What can we do to avoid that seasonal decline in milk protein?  (0:01)Simple things like cooling, fans, and sprinklers can reduce heat stress and increase cow comfort. Dr. Van Amburgh recommends promoting dry matter intake and lying time, with feed available 21-22 hours per day and more than 12 hours of lying time per day. (5:27)Dr. Van Amburgh discusses basic formulation considerations for amino acid balancing including current feed chemical analyses that include NDF digestibility, characterizing the cows appropriately by using accurate body weights, understanding DMI and making sure actual milk lines up with ME and MP allowable milk, assessing body condition changes, and understanding the first limiting nutrient of milk production. Areas where mistakes are often made include using much lighter body weights than actual to formulate rations, not using actual DMI, and using feed library values instead of actual feed chemistry. (8:00)Milk protein percentage and dietary energy are closely aligned. This is often attributed to ruminal fermentation and microbial yield. Sugars, starches, and digestible fiber sources drive microbial yield. While protein and energy metabolism are considered to be separate, that is an artificial divide and they should be considered together. Once adequate energy for protein synthesis is available, providing more dietary protein or amino acids can increase protein synthesis further. Dr. Van Amburgh provides some ranges of target fermentable non-structural carbohydrates, starch, sugar and soluble fiber appropriate for early peak and mid-lactation cows. He speaks about the benefits of adding sugars to the diet instead of trying to continue to increase starch. (11:15)Dr. Van Amburgh details an experiment using more byproduct feeds in a lactation diet to successfully increase intake and subsequently, milk protein content. (24:04)Milk protein increases with higher DCAD in diets, independent of protein level. Increasing DCAD can also lead to increased DMI, probably through better fiber digestion. The mechanism is not completely understood, but perhaps some rumen microbes have a higher requirement for potassium. In another study, feeding higher DCAD resulted in an 11% increase in milk protein yield and a 26% increase in milk fat yield. (32:39)Feeding fatty acids may also improve milk protein via insulin signaling pathways. A 5.6% increase in milk protein was observed when the ratio of palmitic acid to oleic acid was around 1.5:1. (36:21)Dr. Van Amburgh encourages the audience to pay close attention to digestibility of dietary ingredients and shares an analysis of ten different sources of feather meal that varied in digestibility from around 50% up to 75%. (40:10)Dr. Van Amburgh details an experiment targeting optimum methionine and lysine levels for improved milk protein. In an example with 60 Mcals of ME in the diet, the targets were 71 grams of methionine and 193 grams of lysine. (42:00)Questions from the webinar audience were addressed. They included information about the best type of sugars to add to diets, if protozoa are preferentially retained in the rumen, BMR vs conventional corn silage, amino acid supply when dietary crude protein is around 14-15%, using metabolizable energy instead of net energy, variability of animal protein blends, and methionine to lysine ratios. (48:23)To end this podcast, Dr. Jose Santos steps in to invite everyone to the Florida Ruminant Nutrition Symposium in Gainesville held February 24-26.Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In this study, two basal diets were fed, one low-fat and one high-fat. The low-fat diet contained cottonseed meal and cottonseed hulls and the high-fat diet contained whole cottonseed. This balanced fiber and protein to try and make the difference between the basal diets and just the fatty acids. Basal diets were supplemented with two different fat supplements that had different ratios of palmitic and oleic acids. The applied question at hand was “Does fat need to be supplemented to a high-fat basal diet?” (5:32)The low-fat diet contained 1.93% fatty acids and the high-fat diet contained 3.15% fatty acids. Fatty acid supplements were fed at 1.5% of dry matter and replaced soyhulls. The palmitic acid supplement contained 80% palmitic acid and 10% oleic acid. The palmitic + oleic acid supplement contained 60% palmitic acid and 30% oleic acid. Thirty-six cows were used in a split-plot Latin square design, with half the cows on each basal diet. Under each split-plot, cows were allocated to a 3x3 Latin square, evaluating a control treatment (no fat supplement), palmitic acid supplement, and palmitic + oleic acid supplement. (8:46)Bill, Adam, and Clay discuss the increase in milk components the industry has experienced recently due to the powerful combination of genetics and nutrition. Hoard's Dairyman reported that 2024 was the first year that the U.S. had averaged over 4% milk fat going back to 1924 when records began. (13:01)Both fat supplements increased milk yield in low-fat and high-fat basal diets, but the magnitude of the increase was larger in the low-fat diet. The high palmitic acid diet increased milk yield more in cows fed the low-fat basal diet than the palmitic + oleic supplement did. High-fat basal diet cows had similar milk yield responses to both fatty acid supplements. The panel discusses the industry emphasis on milk components and if/when a threshold in performance might happen given the advancement of genomics and nutrition. (15:51)Clay asks Adam to remind the listeners about the relationship between fatty acids and crude fat or ether extract. Adam recommends moving away from ether extract and focusing solely on fatty acid content. Bill, Adam, and Clay talk about the variability in the fatty acid content of various feedstuffs. (25:33)Bill asks if the feed efficiency improvement with the fat supplementation was due to more of a gross energy or digestible/metabolizable energy effect. Adam suggests it may be a little of both. The diet is more energy-dense, but we also know now that some of those specific fatty acids have specific effects. Improvements in NDF digestibility are consistently observed with palmitic acid supplementation. Oleic acid improves fatty acid absorption and has an impact on adipose tissue metabolism and insulin sensitivity. Bill and Adam go on to talk more philosophically about the best way to measure feed efficiency in dairy cows. (29:02)If Adam could do this experiment over again, he would have pushed the basal fat levels a bit more and had both lower-producing and higher-producing cows in the experiment. This leads to a discussion of how the results might have differed if distiller grains or soybeans were used instead of cottonseed in the experiment. Listeners should be careful not to extrapolate the results from this experiment to other fat sources. (33:55)Adam emphasizes that we shouldn't be afraid of feeding high-fat diets, either basal or supplemental fatty acids, especially to high-producing cows. We should be very mindful about where those fatty acids are coming from. We could provide the same nutrients by feeding either cottonseed or distillers grains, but how those ingredients feed out could be very different. (38:38)In summary, Clay agrees we should take a fresh look at how much fat we're feeding cows in basal diets and underlines the importance of the source of supplemental fatty acids. Bill concurs and commends Adam's group for basically making cottonseed without fat in the low-fat basal diet, which allowed for very clean interpretations of the fatty acid supplement results. Adam underlines that we can feed higher fat diets, but the fatty acid profile of all of those ingredients we might use is going to be key. In addition to fatty acids in diets and supplements, de novo synthesis of milk fat from acetate is the other half of the equation. Bringing those together might be a strategy to keep up with genetic improvements and drive higher milk fat yield. (47:43)You can find this episode's journal club paper from JDS Communications here: https://www.sciencedirect.com/science/article/pii/S2666910223001114Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

This Real Science Exchange podcast episode was recorded during a webinar from Balchem's Real Science Lecture Series. You can find it at balchem.com/realscience.Feeding rumen-protected choline in early lactation has consistently increased milk yield and energy-corrected milk yield, which is more pronounced when cows are fed diets low in metabolizable methionine. Choline feeding also increases milk fat and protein yield, minimizes body condition loss in early lactation, and reduces postpartum disease incidence. Dr. McFadden presents three topics about choline biology in the dairy cow. (01:45)Why should we consider fatty acid feeding when feeding methyl donors like choline and methionine?Choline degradation in the rumen and small intestine, focusing on the role of triethylamine oxide Why should we consider lysophosphatidylcholine as an immunomodulator in fresh cows and preweaning calves?Fatty acid nutrition to optimize methyl donor efficiency. (4:02)Fatty liver is a concern for fresh cows because of its relationship with ketosis, poor fertility and compromised milk production. Cows with fatty liver exhibit low circulating concentrations of phosphatidylcholine, which is a component of very low-density lipoproteins (VLDL) that transport triglycerides out of the liver. Feeding rumen-protected choline lowers liver triglyceride deposition by supporting the synthesis of phosphatidylcholine and thus, VLDL. Dr. McFadden goes on to explain the two different pathways for phosphatidylcholine in the liver and how those interact with fatty acid metabolism. He describes several experiments that have investigated how rumen-protected choline and supplemental fatty acids interact in lactating cows. Low phosphatidylcholine supply is a key feature of fatty liver in dairy cows, likely due to low polyunsaturated fatty acid (PUFA) and low choline supplies. Delivery of post-ruminal PUFA may support phosphatidylcholine synthesis with accompanying improvements in insulin sensitivity, body condition maintenance, and inflammation, but interactions with dietary fatty acid digestibility should be considered. Dr. McFadden gives a list of considerations for fresh cow diets incorporating fat and choline supplementation. Gastrointestinal choline degradation and trimethylamine N-oxide (TMAO)  (16:58)Unprotected choline is almost totally degraded in the rumen. Microbes convert choline into trimethylamine (TMA) which is then converted to TMAO in the liver. Rumen-protected choline allows for a large proportion of choline to reach the small intestine intact. However, research shows that choline can also be degraded by microbes in the small intestine in the same pathway, limiting choline bioavailability. Plasma TMAO accumulation is associated with non-alcoholic fatty liver disease, inflammation, insulin resistance, obesity, oxidative stress, and cardiovascular disease in rodent and human models. Little research was available regarding if the relationship between TMAO and poor health was causative or just associative. Dr. McFadden's lab infused cows intravenously with TMAO and found that TMAO did not modify milk production or glucose tolerance in early lactation cows.  TMAO does not appear to influence energy metabolism or health in early lactation cows. Choline is subject to both ruminal and lower-gut degradation to TMA, and that influence on choline bioavailability needs to be defined. Data in non-ruminants suggests that unsaturated fatty acid feeding can shift the gut microbes to slow TMA formation. Lysophosphatidylcholine and immunomodulation (28:45)Dr. McFadden gives an overview of neutrophil activation and the oxidative burst that contributes to pathogen killing. The ability to elicit the oxidative burst is diminished in pre-weaned calves and transition cows. When cows were given endotoxin to cause an immune response, circulating lysophosphatidylcholine was decreased. In rodent models, lysophosphatidylcholine promotes the oxidative burst and suppresses long-term inflammation in response to bacterial infection. Dr. McFadden cultured neutrophils from pre-weaned calves with lysophosphatidylcholine and observed an enhanced oxidative burst.Immunosuppression is characterized by low circulating lysophosphatidylcholine concentrations in dairy cows. In  vitro data suggests lysophosphatidylcholine can activate neutrophils, and rumen-protected choline increases circulating lysophosphatidylcholine. Future research is likely to define an immunomodulatory role for choline. Dr. McFadden takes questions from the webinar audience. (38:07)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Dr. Hernandez recently presented a Real Science Lecture series webinar on this topic. You can find the link at balchem.com/realscience.Dr. Hernandez begins with an overview of how she came to study calcium metabolism in the mammary gland. Over the past number of years, she has worked on research to manipulate what's happening in the mammary gland in the prepartum period to ensure adequate endocrine, nutritional, reproductive, and immunological status. (5:55)The panelists discuss how “normal” has changed when it comes to transition cow health. Dr. Overton reminds listeners that 25 years ago, 6-8% of fresh cows in a herd having clinical milk fever was pretty typical. Now, we accept none of that. Subclinical hypocalcemia was not on the radar then, and we thought we had calcium all figured out. Dr. Hernandez's work shows that this was not the case. She is pleased that a synergism of producers, veterinarians, and academics have been working together to understand the mechanisms of calcium metabolism to find solutions for individual farms based on their situation. (9:22)Dr. Hernandez then discusses various interventions used in the industry, including low-potassium diets, negative DCAD diets, and zeolite clays. The clays are new to the US, and it seems that they work primarily through a phosphorus reduction mechanism and are best limited to feeding 10-14 days pre-calving. (18:14)Dr. Overton asks Dr. Hernandez about a point in her webinar that cows are in negative calcium balance through 150-200 days in milk. She confirms that there are approximately 8.5 kilograms of calcium in the bones of a cow, but we don't know how much of that she loses each lactation. Her dream scenario would be a CT scanner large enough to fit a dairy cow in to evaluate how her bones change throughout lactation. This leads to a discussion of whether or not we should be including higher rates of calcium in dairy cow diets. Dr. Hernandez would like to learn more about what's happening with calcium absorption in the gut in real-time with endocrine status and stage of lactation, which is a challenging task. (23:17)Co-host, Dr. Jeff Elliott, asks if the reason multiparous cows are more prone to milk fever is because they're not as efficient at calcium resorption to the bone. Dr. Hernandez doesn't have a definitive answer, but it could be due to less effective gut absorption with age, or it may be related to the influence of estrogen on bone density. She also mentions it could be endocrine-controlled or even stem cell-related.  (28:59)Dr. Hernandez's hypothesis has always been that you have to have a calcium decrease to trigger the negative feedback loop involved in calcium metabolism. Her advice is to wait until 48 hours to take a blood sample to analyze calcium. This aligns well with epidemiological research on the veterinarian side regarding delayed, persistent, transient, and normal hypocalcemic animals. (33:04)Dr. Overton asks about a calcium-chelation study that Dr. Hernandez's group conducted and whether or not chelating calcium had an impact on colostrum production. It did not in that experiment. Dr. Hernandez was surprised at how much chelating agent was needed to overcome the draw of the mammary gland, but that further underlines how much of a priority lactation is in metabolism. (41:45)Scott asks both panelists their views on what the priority should be for research in this area. Dr. Hernandez's ideas include more research on how zeolite clays work biologically, finding out what's happening in the gut, mammary gland, and bone of a dairy cow at different stages of lactation. She emphasizes that research should be conducted at different stages rather than just extrapolating from one stage to another because lactation is incredibly dynamic. Dr. Overton seconded the idea of a better understanding of zeolite clays and their feeding recommendations, as well as research defining what happens to and where all the calcium is pulled from the bone during lactation. (45:32) In closing, Jeff, Tom, and Laura share their take-home thoughts. Jeff is excited to learn more about how zeolite clays work and if other products may come to the forefront to help in calcium metabolism management. Tom commends Laura on her work and how it has dovetailed so well with the epidemiological research from the veterinary side. Laura reminds listeners that the mammary gland is running the show and is thrilled that her work as a basic scientist is having an applied impact on the dairy industry. (51:17)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Please note the recording was before the new NASEM model was released. However, there is still a lot of good information from Dr. Weiss beyond those recommendations. This Real Science Exchange podcast episode was recorded during a webinar from Balchem's Real Science Lecture Series. You can find it at balchem.com/realscience.Most ration formulation software uses the 2001 NRC mineral equations. The basic concept of the 2001 NRC mineral requirements is to feed enough absorbable minerals to maintain adequate labile body stores and fluid concentrations. Minerals are lost each day via excretion in feces and urine, milk production, and incorporation into tissues or the fetus in the case of growing or pregnant animals. We have decent data to predict mineral concentrations of milk, growth, and the fetus; however, the endogenous loss in feces is much harder to capture. Absorption coefficients (AC) for most minerals are exceedingly difficult to measure. (0:29)The NRC requirements are the means of several experiments. Feeding to the mean results in half the cows being fed adequately or in excess, and half are not fed enough. In human nutrition, recommended daily allowances for vitamins and minerals are calculated as the mean plus two standard deviations, which statistically meets the requirement for 97% of the population. Since the standard deviation of the requirement is hard to acquire, human nutrition uses the same standard deviation for energy metabolism, around 20%. Dr. Weiss feels this is a reasonable safety factor for minerals for animals as well. He recommends feeding about 1.2 times the NRC requirement while keeping an eye on the maximum tolerable limit for the mineral in question. (4:59)How do we measure absorption? We measure the minerals in the diet, we apply AC, and we get grams or milligrams of absorbed minerals available for the animal to use. Dr. Weiss details some of the complex methodology involved in trying to obtain AC. Feces contain not only unabsorbed dietary minerals but also endogenous/metabolic minerals (e.g., intestinal cells, enzymes, etc.) and homeostatic excretion of minerals (e.g., dumping excess minerals). In the 2001 NRC, the endogenous fecal for almost every mineral is a function of body weight, which is incorrect. It should be a function of dry matter intake. (8:40)Endogenous fecal losses can also be measured using stable or radioactive isotopes. This method is extremely expensive and if radioactive isotopes are used, management of radioactive waste becomes an issue. Thus, most of the AC for trace minerals that used these methods are 50-60 years old. (15:33)Dr. Weiss details some of the issues with calcium requirements in the 2001 NRC leading to overestimation of calcium absorption for many calcium sources and overestimation of the maintenance requirement due to endogenous fecal being calculated using body weight. Organic and inorganic phosphorus have different AC, so partitioning between organic and inorganic will give a more accurate estimate of the requirement. (16:33)Potassium has a linear antagonistic effect on magnesium. You can feed more magnesium to overcome this antagonism, but you won't ever eliminate it. If you feed a few percent added fat as long-chain fatty acids, Dr. Weiss recommends feeding 10-20% more magnesium to account for soap formation in the rumen. (19:17)It's much more difficult to measure AC for trace minerals due to multiple antagonists, interactions among different minerals, and regulated absorption. In addition, AC for trace minerals is very low, which means a small change in the AC can have a huge impact on diet formulation. All feeds in the NRC system have the same AC for each trace mineral and we know that's not right.  (25:39)Dr. Weiss gives an overview of different trace mineral antagonisms and interactions and details his approach to formulation if he has absorption data for a particular ingredient. He also gives his estimates of revised AC for several minerals. (28:07)In summary, the factorial NRC approach only fits 50% of the population. Feeding an extra 10-20% above the NRC requirement includes about 97% of the population. We need to continue to account for more sources of variation in AC. Interactions need to be top of mind when considering mineral requirements and diet formulation. (37:39)Dr. Weiss takes a series of questions from the webinar audience. (40:50)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.