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Schluss mit der Heroisierung eines Jahrzehnts! Wer einem aufgewärmte Spachtelmasse als Quick Lunch serviert, es als schick empfindet, sich die neonfarbene Regenjacke in die Hose zu stecken, und sich mit dem eigenen Mundgeruch den Mittelscheitel zurechtrückt, hat es nicht anders verdient. Willkommen in der Dekade der Deformation.Und wir Gebrüder Moped wissen, wovon wir reden. Der eine war der schlechteste Mod der Republik, der andere Mitglied im Anti-Modern-Talking-Club. Nun haben wir euch nach euren abscheulichsten Details der 80er gefragt und dabei mehr als 2000 Antworten bekommen. Eine Neuauflage der Folge #22 “Podcast des Jahres” vom April 2021. ★ Ö3 Podcast AwardNominiere bitte den „Bist du Moped! Podcast“ beim Ö3 Podcast Award!★ Gebrüder Moped ShopShirts, Hoodies, Tassen, Taschen & anderes ZeuxSujet-Fotos: Gebrüder Moped; Shawn Hempel - stock.adobe.comLizenzfreie Musik:Borderline, Life Span/FineTune Music, Adobe Stock ID: 452584056Apple (iMovie, GarageBand)
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John Plotz of Recall This Book spoke in 2020 with Sanjay Krishnan, Boston University English professor and Conrad scholar about his marvelous new book on that grumpiest of Nobel laureates, V. S Naipaul's Journeys. Krishnan sees the “contrarian and unsentimental” Trinidad-born but globe-trotting novelist and essayist as early and brilliant at noticing the unevenness with which the blessings and curses of modernity were distributed in the era of decolonization. Centrally, Naipaul realized and reckoned with the always complex and messy question of the minority within postcolonial societies. He talks with John about Naipaul's early focus on postcolonial governments, and how unusual it was in the late 1950's for colonial intellectuals to focus on “the discomfiting aspects of postcolonial life….and uneven consequences of the global transition into modernity.” Most generatively of all, Sanjay insists that the “troublesome aspect is what gives rise to what's most positive in Naipaul.” Discussed in the Episode Chinua Achebe, There Was a Country (2012) George Lamming, e.g. (In the Castle of My Skin, 1953) V. S. Naipaul, The Suffrage of Elvira (1957) Miguel Street (1959) Area of Darkness (1964) The Mimic Men (1967) A Bend in the River (1979) V. S. Naipaul, A House for Mr. Biswas (1961) V. S. Naipaul, In a Free State (1971) Aya Kwei Armah, The Beautyful Ones Are Not Yet Born (1968) Derek Walcott, “The Antilles: Fragments of Epic Memory” Nobel Acceptance Speech Richard Wright, Native Son (1940) Bill Ashcroft, Gareth Griffiths and Helen Tiffin, The Empire Writes Back (1989 theoretical work on postcolonialism) Aravind Adiga, The White Tiger (2008) Marlon James (eg. The Book of Night Women, 2009) Beyonce, “Formation“ Frantz Fanon, Wretched of the Earth (1961) Tayeb Salih, Season of Migration to the North (1966) Willa Cather “Two Friends” in Obscure Destinies Read Here: 43 Sanjay Krishnan on V. S. Naipaul: To make the Deformation the Formation Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/literary-studies
John Plotz of Recall This Book spoke in 2020 with Sanjay Krishnan, Boston University English professor and Conrad scholar about his marvelous new book on that grumpiest of Nobel laureates, V. S Naipaul's Journeys. Krishnan sees the “contrarian and unsentimental” Trinidad-born but globe-trotting novelist and essayist as early and brilliant at noticing the unevenness with which the blessings and curses of modernity were distributed in the era of decolonization. Centrally, Naipaul realized and reckoned with the always complex and messy question of the minority within postcolonial societies. He talks with John about Naipaul's early focus on postcolonial governments, and how unusual it was in the late 1950's for colonial intellectuals to focus on “the discomfiting aspects of postcolonial life….and uneven consequences of the global transition into modernity.” Most generatively of all, Sanjay insists that the “troublesome aspect is what gives rise to what's most positive in Naipaul.” Discussed in the Episode Chinua Achebe, There Was a Country (2012) George Lamming, e.g. (In the Castle of My Skin, 1953) V. S. Naipaul, The Suffrage of Elvira (1957) Miguel Street (1959) Area of Darkness (1964) The Mimic Men (1967) A Bend in the River (1979) V. S. Naipaul, A House for Mr. Biswas (1961) V. S. Naipaul, In a Free State (1971) Aya Kwei Armah, The Beautyful Ones Are Not Yet Born (1968) Derek Walcott, “The Antilles: Fragments of Epic Memory” Nobel Acceptance Speech Richard Wright, Native Son (1940) Bill Ashcroft, Gareth Griffiths and Helen Tiffin, The Empire Writes Back (1989 theoretical work on postcolonialism) Aravind Adiga, The White Tiger (2008) Marlon James (eg. The Book of Night Women, 2009) Beyonce, “Formation“ Frantz Fanon, Wretched of the Earth (1961) Tayeb Salih, Season of Migration to the North (1966) Willa Cather “Two Friends” in Obscure Destinies Read Here: 43 Sanjay Krishnan on V. S. Naipaul: To make the Deformation the Formation Learn more about your ad choices. Visit megaphone.fm/adchoices
John Plotz of Recall This Book spoke in 2020 with Sanjay Krishnan, Boston University English professor and Conrad scholar about his marvelous new book on that grumpiest of Nobel laureates, V. S Naipaul's Journeys. Krishnan sees the “contrarian and unsentimental” Trinidad-born but globe-trotting novelist and essayist as early and brilliant at noticing the unevenness with which the blessings and curses of modernity were distributed in the era of decolonization. Centrally, Naipaul realized and reckoned with the always complex and messy question of the minority within postcolonial societies. He talks with John about Naipaul's early focus on postcolonial governments, and how unusual it was in the late 1950's for colonial intellectuals to focus on “the discomfiting aspects of postcolonial life….and uneven consequences of the global transition into modernity.” Most generatively of all, Sanjay insists that the “troublesome aspect is what gives rise to what's most positive in Naipaul.” Discussed in the Episode Chinua Achebe, There Was a Country (2012) George Lamming, e.g. (In the Castle of My Skin, 1953) V. S. Naipaul, The Suffrage of Elvira (1957) Miguel Street (1959) Area of Darkness (1964) The Mimic Men (1967) A Bend in the River (1979) V. S. Naipaul, A House for Mr. Biswas (1961) V. S. Naipaul, In a Free State (1971) Aya Kwei Armah, The Beautyful Ones Are Not Yet Born (1968) Derek Walcott, “The Antilles: Fragments of Epic Memory” Nobel Acceptance Speech Richard Wright, Native Son (1940) Bill Ashcroft, Gareth Griffiths and Helen Tiffin, The Empire Writes Back (1989 theoretical work on postcolonialism) Aravind Adiga, The White Tiger (2008) Marlon James (eg. The Book of Night Women, 2009) Beyonce, “Formation“ Frantz Fanon, Wretched of the Earth (1961) Tayeb Salih, Season of Migration to the North (1966) Willa Cather “Two Friends” in Obscure Destinies Read Here: 43 Sanjay Krishnan on V. S. Naipaul: To make the Deformation the Formation Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/biography
John Plotz of Recall This Book spoke in 2020 with Sanjay Krishnan, Boston University English professor and Conrad scholar about his marvelous new book on that grumpiest of Nobel laureates, V. S Naipaul's Journeys. Krishnan sees the “contrarian and unsentimental” Trinidad-born but globe-trotting novelist and essayist as early and brilliant at noticing the unevenness with which the blessings and curses of modernity were distributed in the era of decolonization. Centrally, Naipaul realized and reckoned with the always complex and messy question of the minority within postcolonial societies. He talks with John about Naipaul's early focus on postcolonial governments, and how unusual it was in the late 1950's for colonial intellectuals to focus on “the discomfiting aspects of postcolonial life….and uneven consequences of the global transition into modernity.” Most generatively of all, Sanjay insists that the “troublesome aspect is what gives rise to what's most positive in Naipaul.” Discussed in the Episode Chinua Achebe, There Was a Country (2012) George Lamming, e.g. (In the Castle of My Skin, 1953) V. S. Naipaul, The Suffrage of Elvira (1957) Miguel Street (1959) Area of Darkness (1964) The Mimic Men (1967) A Bend in the River (1979) V. S. Naipaul, A House for Mr. Biswas (1961) V. S. Naipaul, In a Free State (1971) Aya Kwei Armah, The Beautyful Ones Are Not Yet Born (1968) Derek Walcott, “The Antilles: Fragments of Epic Memory” Nobel Acceptance Speech Richard Wright, Native Son (1940) Bill Ashcroft, Gareth Griffiths and Helen Tiffin, The Empire Writes Back (1989 theoretical work on postcolonialism) Aravind Adiga, The White Tiger (2008) Marlon James (eg. The Book of Night Women, 2009) Beyonce, “Formation“ Frantz Fanon, Wretched of the Earth (1961) Tayeb Salih, Season of Migration to the North (1966) Willa Cather “Two Friends” in Obscure Destinies Read Here: 43 Sanjay Krishnan on V. S. Naipaul: To make the Deformation the Formation Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/caribbean-studies
John Plotz of Recall This Book spoke in 2020 with Sanjay Krishnan, Boston University English professor and Conrad scholar about his marvelous new book on that grumpiest of Nobel laureates, V. S Naipaul's Journeys. Krishnan sees the “contrarian and unsentimental” Trinidad-born but globe-trotting novelist and essayist as early and brilliant at noticing the unevenness with which the blessings and curses of modernity were distributed in the era of decolonization. Centrally, Naipaul realized and reckoned with the always complex and messy question of the minority within postcolonial societies. He talks with John about Naipaul's early focus on postcolonial governments, and how unusual it was in the late 1950's for colonial intellectuals to focus on “the discomfiting aspects of postcolonial life….and uneven consequences of the global transition into modernity.” Most generatively of all, Sanjay insists that the “troublesome aspect is what gives rise to what's most positive in Naipaul.” Discussed in the Episode Chinua Achebe, There Was a Country (2012) George Lamming, e.g. (In the Castle of My Skin, 1953) V. S. Naipaul, The Suffrage of Elvira (1957) Miguel Street (1959) Area of Darkness (1964) The Mimic Men (1967) A Bend in the River (1979) V. S. Naipaul, A House for Mr. Biswas (1961) V. S. Naipaul, In a Free State (1971) Aya Kwei Armah, The Beautyful Ones Are Not Yet Born (1968) Derek Walcott, “The Antilles: Fragments of Epic Memory” Nobel Acceptance Speech Richard Wright, Native Son (1940) Bill Ashcroft, Gareth Griffiths and Helen Tiffin, The Empire Writes Back (1989 theoretical work on postcolonialism) Aravind Adiga, The White Tiger (2008) Marlon James (eg. The Book of Night Women, 2009) Beyonce, “Formation“ Frantz Fanon, Wretched of the Earth (1961) Tayeb Salih, Season of Migration to the North (1966) Willa Cather “Two Friends” in Obscure Destinies Read Here: 43 Sanjay Krishnan on V. S. Naipaul: To make the Deformation the Formation Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
The geological history of most regions is shaped by a whole range of processes that occur at temperatures ranging from above 800°C to as low as 100°C. The timing of events occurring over a particular temperature range can be recorded by a mineral which crystallizes over that range. The mineral calcite is suitable for recording low-temperature processes such as fossilization, sedimentation, and fluid flow, and it is especially useful as it is virtually ubiquitous. But using uranium-lead radiometric dating in calcite is very challenging as it often contains very little uranium and the ragiogenically-produced lead isotopes can be swamped by common lead within a calcite crystal. In the podcast, Catherine Mottram explains how these challenges are being overcome and shares some of her findings based on radiometric dating of calcite. Mottram is an Associate Professor of Geology at the University of Portsmouth.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.08.01.551512v1?rss=1 Authors: Xu, H., Dugue, G., Cantaut-Belarif, Y., Lejeune, F.-X., Gupta, S., Wyart, C., Lehtinen, M. K. Abstract: Reissner's fiber (RF) is an extracellular polymer comprising the large monomeric protein SCO-spondin (SSPO) secreted by the subcommissural organ (SCO) that extends through cerebrospinal fluid (CSF)-filled ventricles into the central canal of the spinal cord. In zebrafish, RF and CSF-contacting neurons (CSF-cNs) form an axial sensory system that detects spinal curvature, instructs morphogenesis of the body axis, and enables proper alignment of the spine. In mammalian models, RF has been implicated in CSF circulation. However, challenges in manipulating Sspo, an exceptionally large gene of 15,719 nucleotides, with traditional approaches has limited progress. Here, we generated a Sspo knockout mouse model using CRISPR/Cas9-mediated genome-editing. Sspo knockout mice lacked RF-positive material in the SCO and fibrillar condensates in the brain ventricles. Remarkably, Sspo knockout brain ventricle sizes were reduced compared to littermate controls. Minor defects in thoracic spine curvature were detected in Sspo knockouts, which did not alter basic motor behaviors tested. Altogether, our work in mouse demonstrates that SSPO and RF regulate ventricle size during development but only moderately impact spine geometry. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.10.548429v1?rss=1 Authors: Warner, H., Franciosa, G., van der Borg, G., Faas, F., Koenig, C., de Boer, R., Classens, R., Maassen, S., Baranov, M., Mahajan, S., Dabral, D. D., Coenen, B., Bianchi, F., van Hilten, N., Risselada, H. J., Roos, W. H., Olsen, J., Querol Cano, L., van den Bogaart, G. V. Abstract: To mount an adaptive immune response, dendritic cells must process antigens, migrate to lymph nodes and form synapses with T cells. Critical to 3D migration and mechanosensing is the nucleus, which is the size-limiting barrier for navigation through gaps in the extracellular matrix. Here, we show that inflammatory activation of dendritic cells leads to the nucleus becoming spherically deformed, and enables dendritic cells to overcome the typical 2 to 3 micron pore limit for 3D migration. We show that the nuclear shape-change is partially attained through reduced cell adhesion, whereas improved migration through extracellular matrix is achieved through reprogramming of the actin cytoskeleton. Specifically we show that phosphorylation of cofilin-1 at serine 41 drives the assembly of a CofilinActoMyosin (CAM)ring proximal to the nucleus and enhances migration through 3D collagen gels. In summary, these data describe novel signaling events through which dendritic cells simultaneously deform their nucleus and enhance their migratory capacity; molecular events that may be recapitulated in other contexts such as wound healing and cancer. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.02.547395v1?rss=1 Authors: Corniani, G., Lee, Z. S., Carre, M. J., Lewis, R., Delhaye, B. P., Saal, H. P. Abstract: The human fingertip can detect small tactile features with a spatial acuity roughly the width of a fingerprint ridge. However, how individual ridges deform under contact to support accurate and high-precision tactile feedback is currently unknown. The complex mechanical structure of the glabrous skin, composed of multiple layers and intricate morphology within which mechanoreceptors are embedded, makes this question challenging. Here, we used optical coherence tomography to image and track sub-surface deformations of hundreds of individual fingerprint ridges during contact events at high spatial resolution in vivo. We calculated strain patterns in both the stratum corneum and viable epidermis in response to a variety of tactile stimuli, including static indentation, stick-to-slip events, sliding of a flat surface in different directions, and interaction with small tactile features, such as edges and grooves. We found that ridges could stretch, compress, and undergo considerable shearing orthogonal to the skin surface, but there was limited horizontal shear. Therefore, it appears that the primary components of ridge deformation and, potentially, neural responses are deformations of the ridge flanks and their relative movement, rather than overall bending of the ridges themselves. We conclude that the local distribution of mechanoreceptors across the ridges might be ideally suited to extract the resulting strain gradients and that the fingertip skin may possess a higher mechanical spatial resolution than that of a single ridge. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
NEWS: Increased seismic activity, ground deformation recorded over Mayon | June 27, 2023Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribe Visit our website at https://www.manilatimes.net Follow us: Facebook - https://tmt.ph/facebook Instagram - https://tmt.ph/instagram Twitter - https://tmt.ph/twitter DailyMotion - https://tmt.ph/dailymotion Subscribe to our Digital Edition - https://tmt.ph/digital Check out our Podcasts: Spotify - https://tmt.ph/spotify Apple Podcasts - https://tmt.ph/applepodcasts Amazon Music - https://tmt.ph/amazonmusic Deezer: https://tmt.ph/deezer Stitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tunein#TheManilaTimes Hosted on Acast. See acast.com/privacy for more information.
Spokes are often one of the most overlooked but important components of a cycling wheel. Most people think spokes are all the same but this could not be further from the truth. On this episode of FASTER we discuss why we use Sapim CX-Ray spokes for all of our wheels and why understanding elastic and plastic deformation, fatigue, and creep will help you make the best choices for spokes and wheels. Listen to this episode to learn about the mechanical properties of spokes and how picking the right spokes will keep you riding and make you faster. Watt Points: 5
Here is a clip from Yesterday's show. Today Doc discusses the fact that Fox News had to pay almost $800 Million in defamation over Carlson's coverage of the 2020 Election.Website - https://www.thatsonpoint.infoMerch - https://teespring.com/stores/thats-on-point-meFollow Us On;Bitchute-https://www.bitchute.com/channel/8SXcz1rqDyu7/YouTube-https://www.youtube.com/channel/UCRNHroldv9kuaatarS7uclAMinds-https://www.minds.com/thatsonpoint/Top Clips: https://www.youtube.com/channel/UCn_fZ4JhHN05YLijsdmkYSQ/Paler:https://parler.com/profile/DocComeauSupport Us On;Subscribe Star-https://www.subscribestar.com/that-s-on-pointPatreon-https://www.patreon.com/ThatsOnPoint?fan_landing=tru
Here is a clip from Yesterday's show. Today Doc discusses the fact that Fox News had to pay almost $800 Million in defamation over Carlson's coverage of the 2020 Election.Website - https://www.thatsonpoint.infoMerch - https://teespring.com/stores/thats-on-point-meFollow Us On;Bitchute-https://www.bitchute.com/channel/8SXcz1rqDyu7/YouTube-https://www.youtube.com/channel/UCRNHroldv9kuaatarS7uclAMinds-https://www.minds.com/thatsonpoint/Top Clips: https://www.youtube.com/channel/UCn_fZ4JhHN05YLijsdmkYSQ/Paler:https://parler.com/profile/DocComeauSupport Us On;Subscribe Star-https://www.subscribestar.com/that-s-on-pointPatreon-https://www.patreon.com/ThatsOnPoint?fan_landing=tru
Fox News will pay $787.5 million, less than half of what they were originally being sued for, to end Dominion Voting Systems' lawsuit. The money saves the network from seeing some of its best-known anchors and executives on the stand. Dominion accused Fox News of knowingly spreading lies about its voting machines after the 2020 election.
Today we have Amy's tips for dealing with stress, it's potential good and bad effects on us, and how stress manifests as we grow older. Based on her own personal experiences with battling cancer, losing weight and coaching people, she gives us her tips to manage stress no matter your age. Listen in for these nuggets to help us continue to become our best selves! Sign up here to do the 5 for 50 challenge with us! If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser and Castbox. Sign up for the next Follow-Through Challenge Follow me on Social Media:Amy on IGAmy on FacebookCheck out the Amy Ledin WebsiteJoin the Follow-Through Challenge offered every 6 weeksAmy Ledin's 16-week Fat Loss Academy Resources:Lean Bodies Consulting (LBC)Follow LBC on IGCheck out the LBC Community on FBLBC University#5for50 #5for50FamilyEdition #AmyLedin #AmyLedin.com #ErikLedin #LeanBodiesConsulting #LBC #Kamele #KamelePerez
On May 19th, Fox News was hit with a defamation suit by Dominion Voting Systems. This followed after numerous reports made by Fox News personalities that relied on false information and baseless conspiracy theories that attempted to link Dominion to voter fraud in the 2020 election. In February 2021, a judge ruled in favor of Dominion and denied Fox's motion to dismiss. The judge noted that Fox's statements were "not supported by facts," and found them to be defamatory. The case is now ongoing, with both sides continuing to present evidence before the court. #FoxNews #DominionVotingSystems #DefamationSuit
Dr. Gavin Ashenden, a former chaplain of the Queen's court, joins Anthony and Rob to discuss his arrests and interrogations by the KGB, the seeming disintegration of the Anglican Communion, gender insanity and multiculturalism in the UK, as well as Anglican rising star, Calvin Robinson.#Christian #Catholic #anglican ********************************************************Avoiding Babylon was started during the height of the COVID-19 pandemic. During these difficult and dark days, when most of us were isolated from family, friends, our parishes, and even the Sacraments themselves, this channel was started as a statement of standing against the tyrannical mandates that many of us were living under. Since those early days, this channel has morphed into an amazing community of friends…no…more than friends…Christian brothers and sisters…who have grown in joy and charity.Avoiding Babylon does not criticize the hierarchy or institutional Church, especially Pope Francis. We recognize there is an unprecedented crisis in the Church, but we feel that there are other shows that address these issues that are more qualified than us. Instead, we try to remind ourselves and those who enjoy the channel that being Catholic is a joyful and exciting experience. We seek true Catholic fraternity and eutrapelia with other Catholics who, like us, are doing their best to live out their vocation with the help of God's Grace. Above all, we try to bring humor and joy to the craziness of this fallen world, for as Hillaire Belloc has famously said:“Wherever the Catholic sun doth shine,There's always laughter and good red wine.At least I've always found it so.Benedicamus Domino!”https://www.avoidingbabylon.comTelegram Chat: https://t.me/+AMwZ2f9ChPg5NWNhRSS Feed for Podcast Apps: https://feeds.buzzsprout.com/1987412.rssSpiritusTV: https://spiritustv.com/@avoidingbabylonRumble: https://rumble.com/c/c-1626455Odysee: https://odysee.com/@AvoidingBabylon Support the showCheck out our new store!
In this new series, our team unpacks Flourishing Grace's pursuits. Pastor Josh Knight introduces our value of Formation and how the world seeks to deform us. The text is Matthew 5:13.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.21.521394v1?rss=1 Authors: Damstra, H. G., Passmore, J. B., Serweta, A. K., Koutlas, I., Burute, M. P., Meye, F. J., Akhmanova, A., Kapitein, L. C. Abstract: Expansion microscopy (ExM) is a powerful technique to overcome the diffraction limit of light microscopy by physically expanding biological specimen in three dimensions. Nonetheless, using ExM for quantitative or diagnostic applications requires robust quality control methods to precisely determine expansion factors and to map deformations due to anisotropic expansion. Here we present GelMap, a flexible workflow to introduce a fluorescent grid into pre-expanded hydrogels that scales with expansion and reports deformations. We demonstrate that GelMap can be used to precisely determine the local expansion factor and to correct for deformations without the use of cellular reference structures or pre-expansion ground truth images. Moreover, we show that GelMap aids sample navigation for correlative uses of expansion microscopy. Finally, we show that GelMap is compatible with expansion of tissue and can be readily implemented as a quality control step into existing ExM workflows. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.22.517574v1?rss=1 Authors: Kuhn, C. C., Basnet, N., Bodakuntla, S., Alvarez- Brecht, P., Nichols, S., Martinez-Sanchez, A., Agostini, L., Soh, Y.-M., Takagi, J., Biertumpfel, C., Mizuno, N. Abstract: SARS-CoV-2 is a novel coronavirus responsible for the COVID-19 pandemic. Its high pathogenicity is due to SARS-CoV-2 spike protein (S protein) contacting host-cell receptors. A critical hallmark of COVID-19 is the occurrence of coagulopathies. Here, we report the direct observation of the interactions between S protein and platelets. Live imaging showed that the S protein triggers platelets to deform dynamically, in some cases, leading to their irreversible activation. Strikingly, cellular cryo-electron tomography revealed dense decorations of S protein on the platelet surface, inducing filopodia formation. Hypothesizing that S protein binds to filopodia-inducing integrin receptors, we tested the binding to RGD motif-recognizing platelet integrins and found that S protein recognizes integrin v{beta}3. Our results infer that the stochastic activation of platelets is due to weak interactions of S protein with integrin, which can attribute to the pathogenesis of COVID-19 and the occurrence of rare but severe coagulopathies. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Episode: 2806 Thor, the god of thunder, engineering behind comic books, college courses that deal with fracture.
Seit Jahren verspricht der Staat Bürokratie-Entlastungen. Stattdessen kommen immer neue Vorschriften – und die kosten Unternehmen im Schnitt 2,5 Prozent ihres Jahresumsatzes. *** Hier geht's zu unserem Abo-Angebot für unsere Morning Briefing Leser: https://www.handelsblatt.com/mehrerfahren
Qualzucht, also züchterisch bedingte Deformation, betrifft die unterschiedlichsten Tierarten. Die Liste ist erschreckend lang, sie reicht vom Goldfisch bis zum arabischen Vollblut. Wozu brauchen Menschen Tiere, die nur unter körperlichen Beeinträchtigungen leben können?
Wie sieht es um unsere automobile Zukunft aus? Hat sie überhaupt noch eine? Fragen, mit denen sich der Stuttgarter Künstler Stefan Rohrer auseinandersetzt. Dazu zerlegt er in seinem Atelier in den Stuttgarter Wagenhallen Oldtimer und Motorräder, dehnt und streckt sie, so dass sie in ihrer Deformation aussehen wie ein langgezogener Kaugummi. Seine Fahrzeuge winden sich spiralförmig um Laternenpfähle oder um die eigene Achse. Es ist ein fantasievolles Spiel mit Perspektive, Wahrnehmung und mit der Geschwindigkeit. Gleichzeitig aber auch eine Kritik an der Zukunft des Deutschen liebsten Kindes.
In this episode of Pipeline Things, Things 20 and 21 get into another ILI technology, geometry tools. Christopher and Rhett compare geometry tools to the middle child of ILI technologies compared to EMAT or MFL. They get into different types of geometry tools, deformation tools, and the differences between wrinkles, ripples, and buckles. Highlights: - The difference between wrinkles, ripples, and buckles - Different types of geometry tools - Deformation tools - Validation - What can you get reported? Christopher & Rhett want to answer your questions on an upcoming episode! Connect: Rhett Dotson Christopher De Leon ADV Integrity Be sure to subscribe and leave a comment or rating! Pipeline Things is presented by ADV Integrity and produced by ADV Marketing.
In this episode of The Silent War: Over a dozen FBI whistleblowers have stepped forward, as the system continues to escalate its war on dissenters. Monkeypox is exposing perverts and child rapists everywhere, as we know its spreading primarily through anal sex. Including one unlucky dog victim. New Moderna Documents reveal alarming new symptoms to expect for the vaxxed.If you wish to support our work by donating - Bitcoin Accepted.https://NemosNewsNetwork.com/DonateFALL ASLEEP FAST - Stay Asleep Longer... Without Negative Side Effects.https://redpillliving.com/sleepFor breaking news from one of the most over the target and censored names in the world join our 100% Free newsletter at www.NemosNewsNetwork.com/newsFollow on Truth Socialhttps://truthsocial.com/@REALDUSTINNEMOSAlso follow us at Gabhttps://gab.com/nemosnewsnetworkProtect yourself by buying gold;Nemosnewsnetwork.com/goldNemos News is 100% listener funded. Thank you for your support in our mission to Break the Cycle of Fake News.If you value our work please consider supporting us with our vetted patriot sponsors!www.NemosNewsNetwork.com/sponsorsShop Patriot & Detox the Deep State with www.RedPillLiving.com, Home of Sleepy Joe - the world's most powerful all natural sleep formula & The Great Awakening Gourmet Coffee for Patriots."Our Specialty, is Waking People Up."Other Linkshttps://TheSerapeum.com - Your Archive of The Hidden History of Mankind, and The Mystery Babylon Religion of The Deep State.Join our Telegram chat: https://NemosNewsNetwork.com/chat
Dr. Luke Donovan summarizes the article titled "Talar Cartilage Deformation and Spatiotemporal Gait Patterns in Individuals with and without Chronic Ankle Instability" by Dr. Kyle Kosik and colleagues. Article: https://bit.ly/3OF5SuL
Framestore's Theo Jones and Leo Hills join Ian Failes from befores & afters to discuss the studio's FIRA machine learning tech, used for the extension of proprietary simulation and rigging tools to real-time workflows.
Laut jüngsten Umfragen ist Robert Habeck beliebter als Bundeskanzler Olaf Scholz. Dabei verfolgt er momentan eine umstrittene und gerade für seine Partei schmerzhafte Politik: Um Deutschland angesichts des Krieges in der Ukraine von russischer Energie unabhängig zu machen, ging der Bundeswirtschafts- und Klimaminister Deals mit Katar ein. Wie plant Habeck, die Versorgungssicherheit mit Energie in Deutschland sicherzustellen? Und was wird geschehen, falls Russland Europa selbst das Gas abdreht? Habeck hält einen Lieferstopp von russischem Gas für möglich: "Dass das ausgeschlossen ist, würde niemand, der bei Sinn und Verstand ist, behaupten", so der Vizekanzler im Gespräch mit Mariam Lau und Roman Pletter bei der Langen Nacht der ZEIT in Hamburg. Um Versorgungsengpässen vorzubeugen, gebe es zwei Möglichkeiten: "Entweder man gibt den Unternehmen Geld", das falle aber früher oder später auf die Steuerzahler zurück. Oder man erlaube den Unternehmen, die Preise direkt an die Kunden weiterzugeben. Das sei allerdings "ein sehr, sehr scharfes Schwert, das wir noch nicht gezogen haben, weil wir noch an anderen Möglichkeiten arbeiten, die vielleicht den Keil nicht so scharf in die Gesellschaft treiben. Aber ausschließen kann ich das auch nicht." Europa habe sich seit Beginn des Ukraine-Krieges zum Positiven verändert, findet Habeck. Es gebe "eine ganz große Solidarität, auch mit der Ukraine, aber auch mit diesem Land". Habeck weiter: "Irgendwie ist Europa stärker geworden." Auch Deutschland sei "vielleicht sogar ein bisschen solidarischer geworden. Und ich glaube, ohne zu spoilern, von der Solidarität werden wir noch ein ganzes schönes Stück brauchen im nächsten halben Jahr oder Jahr." Als Politiker sei es ihm wichtig, das Zuhören nicht zu verlernen, so Habeck. Es sei "auch eine professionelle Deformation, die man auch später bei einigen merkt, dass man immer glaubt, man muss derjenige sein, der entscheidet. Und das wieder loszuwerden, ist auch was Gutes."
Zwei Doofe, eine Tanke - Die Wahrheit mit Wenzel und Olumbo.
Diesmal mit Höhenflügen, Festivals, Deformation profesionell, Stagediving, Ischgl und Sicherheit, Kitzloch, Dubai, den Ölkonzernen, Sand im Po, Lotto, Olfaktorik mit Meer und Gras, Herrn Schlaps, Unsere allgemeinen Datenschutzrichtlinien finden Sie unter https://art19.com/privacy. Die Datenschutzrichtlinien für Kalifornien sind unter https://art19.com/privacy#do-not-sell-my-info abrufbar.
Listen as Blu discusses Amber Heard latest claims against Johnny Depp. --- Send in a voice message: https://anchor.fm/thehollywooddeli/message
Elektrosmog ist ein Begriff, den wir alle kennen und der in den letzten Jahren an Bedeutung gewonnen hat. Die Strahlung von künstlich erzeugten elektromagnetischen Feldern (kurz EMF) betrifft uns alle und unsere hohe Sensibilität kann sich auch in diesem Bereich zeigen. Elektrosmog kann ein konstant belastender und beeinflussender Faktor im Leben sein, denn diese Strahlung ist allgegenwärtig. Manche Menschen reagieren sehr intensiv darauf, z.B. mit Hautrötung, Kribbeln und Müdigkeit, Konzentrationsprobleme, Schwindel, Herzklopfen, Verdauungsprobleme oder auch Schlafstörungen und gelten als elektrosensibel. Kennst du das auch? Christian klärt uns in diesem Interview wissenschaftlich fundiert und tiefgreifend auf. Wer elektrosensibel ist, ist weder krank noch verrückt. Er reagiert lediglich überdurchschnittlich sensitiv auf die Belastung durch diese Felder. Menschen, die darunter leiden, spüren die Verschmutzung durch Elektrosmog körperlich. Weitere Auswertungen des Phänomens der besonderen Sensibilität auf Elektrizität können auch Wetterfühligkeit oder eine strarke Reaktion auf Vollmond sein. Da Wetterumschwünge elektrische Ladungsverschiebungen in der Atmosphäre mit sich bringen und bei Vollmond die Ionosphäre der Erde beeinflusst wird, sind diese Zusammenhänge nach dem heutigen Erkenntnisstand logisch erklärbar. Noch mehr Infos findest du hier: https://christian-dittrich-opitz.de/elektrosmog-und-5g-problem-hintergrund-und-losung/ Christian stellt in diesem Interview einen bewährten Lösungsansatz vor, in dessen Mittelpunkt die Produkte von Black Stone Protection stehen. Dafür gewährt er allen Hörern dieses Podcasts einen Rabattcode auf seine Produkte. Name des Rabattcodes: “Sensibel10” “Rabattcode ins Feld „Bemerkungen“ während des Einkaufvorgangs eingeben. Der Rabatt wird von der Shop-Software nicht ausgewiesen. Bestellt ihr auf Rechnung, die dann der Lieferung beiliegt, seht ihr dort den rabattierten Zahlbetrag. Für Paypal gilt: Die Zahlung erfolgt ohne Rabattabzug. Ihr bekommt binnen 24 Std. den zu viel bezahlten Betrag per Paypal rückerstattet.” https://amrita.de/black-stone-protection-m-21317.html Über Christian: Als Jugendlicher erkrankte ich an einer Deformation der Wirbelsäule, die medizinisch als unheilbar eingestuft wurde. Durch Methoden der inneren Kampfkünste und Ernährung erlebte ich komplette Heilung und so kam ich auf meinen Berufsweg, ganzheitliche Methoden zur Unterstützung von Selbstheilung zu studieren und zu vermitteln. Seit 1994 erforsche ich die Auswirkungen von Elektrosmog und die Möglichkeiten, diese zu neutralisieren. Dabei sehe ich einen ganzheitliche Lösungsansatz in einer Technologie, die auf traditionelle Sichtweisen. u.a. der vedischen Mathematik und Erkenntnisse der modernen Physik aufbaut, ebenso wie in der Kultivierung der körpereigenen Lebensenergie.
The air is clearing!In this episode, we discuss the geology of Great Smoky Mountain National Park. We've been neglectful of this region of the U.S. and it's time to do these amazing mountains justice.We begin by discussing why the Smokies are Smoky. It's an interesting and natural phenomenon that involves the immense pine forests. After we get the biology out of the way, we dive into the geology. We broke it down to 3 major geologic events: 1- the bedrock geology and the accumulation of a massive amount of sediment from the breakup of Rodinia (a super-continent that preceded Pangaea). 2- Deformation and mountain building from the Pangaea collision. 3- Erosion as Pangaea broke apart. We hope you enjoy!——————————————————Instagram: @planetgeocastTwitter: @planetgeocastFacebook: @planetgeocastEmail: planetgeocast@gmail.comWebsite: https://planetgeocast.buzzsprout.com/
Pastor Nick preaches on the desires of the flesh.
Someone asked a few questions about the secretive, satanic cult of Aga Khan and Mufti Tariq Masood briefly answered.Zahir and Baatin DO NOT ClashQur'an definitely has a Zahir and Baatin, but that doesn't mean the two are in clash with each other. The Agakhani belief that they possess some hidden knowledge of the Qur'an that goes against clear verses of the Qur'an is totally ignorant and misleading.Quran's Zahir and Batin are not contradictory.Deformation of IslamAgakhanis interpret, rather misinterpret, the Qur'an according to liberal philosophies of Aga Khan and his western allies. They call it Baatin. Ironically, there's nothing hidden or Baatin about liberalism. Liberal philosophy is public information.Aga Khan desires Islam to have a similar reformation, rather deformation, as Christianity.Prophet Muhammad's son-in-law is NOT his biological sonHazrat Ali (RA) was Prophet Muhammad (pbuh)'s son-in-law, not his biological son. Hazrat Ali never claimed to be the direct or indirect descendant of Prophet Muhammad (pbuh). So how on earth can Aga Khan claim to be the "direct descendant" of Prophet Muhammad (pbuh)??!Anybody can claim anything. Aga Khan has failed to substantiate his claim, given the dozens of missing links in his Anglo-Persian lineage.Dua does NOT supersede Salaah (Namaz)First of all, worshiping and invoking Aga Khan, making supplication to him to forgive your sins is not Dua. That's the opposite of Dua. That's Shirk and Shirk invites the wrath of Allah.Secondly, Dua does not supersede the obligatory Salaah. There is no justification for that. Dua has its own place and Salaah is Fardh (obligatory). Not performing Salaah makes us sinful!Website: agakhanism.comYoutube: AgaKhanismOfficialTwitter: @AgaKhanismFacebook: AgaKhanismSupport the show (https://www.patreon.com/AgaKhanism)
How did science and politics get so hopelessly intertwined? We're working on the mystery - and going wherever it leads...
Themes in this talk• Manifestation of divine love• Deformation of Love by human consciousness• Experience and expression of experienceAbout the projectMirra Alfassa, known as the Mother of the Sri Aurobindo Ashram, was Sri Aurobindo's partner and counterpart in every way. They had the same spiritual realisations and they worked for the same goal; to bring the New Consciousness for mankind. Mother was a true Guru, and a Universal Guru in every way. Her teaching has something for everyone because she taught for human progress on all levels and in all parts of the human being. The clarity and simplicity of her expression communicates something to everyone who reads her books. Her inner work included changing those who came to her; both those who were able to meet her physically and those who could come only in their inner being. Her consciousness was active on the universal subtle planes of creation, and she worked to enlighten thought and life impulse on a universal scale for all of mankind.Mother established the Sri Aurobindo Ashram after November 24, 1926, when Sri Aurobindo retired to devote all his time to bringing the New Consciousness. She established the Ashram School in 1943, and taught the students French. From 1950 through 1958, in French, she taught them the highest, deepest, most complex spiritual and yogic philosophy and practice in a simple and easily understandable manner. She gave a realistic and practical view of Sri Aurobindo's philosophy and the practice of his Yoga. These classes were transcribed and published as “Mother's Questions and Answers”. The present series of Auroville Radio talks on Mother's Questions and Answers begins on the date of July 12, 1955, because it is the first date of the available sound recordings of Mother teaching the class. The original recording of Mother's class is part of the Radio Talk. It can be heard at the end of each talk. It is well worth listening to even of one does not understand French, because it imparts something of Mother's consciousness to the listener.
Commentary by Dr. Valentin Fuster
In this episode, we catch up with Coach Jenny for our first pep-talk of the New Year, and hear all about how it's OK to give yourself space and grace when there is extra stress and pressure in your daily routine. With the current COVID circumstances we continue to face challenges and upheaval, and Jenny reminds us that it's OK to to disconnect, it's OK to take the time to nourish your soul and it's OK to listen to your body and give yourself the time and TLC you need to stay healthy and focused. Life, as we know it, is a series of chaotic impactful lessons and experiences; in this episode we're reminded that giving yourself time and comfort can provide the mental and emotional strength you need to keep the needle moving forward. Free guide for fitness coaches If you are interested in a Body Transformation, please use this link and fill out the Questionnaire If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser and Castbox. STRONG Fitness Magazine Subscription Use discount code STRONGGIRLResourcesSTRONG Fitness MagazineSTRONG Fitness Magazine on IGTeam Strong GirlsCoach JVBFollow Jenny on social mediaInstagramFacebookYouTube
How many tabs are open in your browser right now? How many tasks are on your mind while you also try to read this caption? Are you giving any one thing your full attention? Chances are, you're probably reading this while also attempting to do something else. Linda Stone, a tech writer and consultant, said that, “Continuous partial attention is our new default setting.” That was in 1998. In the last 20 years, this "continuous partial attention" has only become more partial because of technology. When "continuous partial attention" is our default, it debilitates our capacity to hear, see, adore, petition, experience, and commune with God, what Christians call prayer. In this series, Unhurried Rhythms, we're walking through everyday rhythms to help you live an unhurried life in the Way of Jesus. There is no shortcut to spiritual maturity, but we hope to remove the stumbling blocks of shame and intimidation from practicing spiritual rhythms. This week, we're taking a practical deep dive into the topic of prayer. You'll learn a few tangible ways to practice prayer, and walk away with the tools to integrate this rhythm into your day. ----------------- Catch up on the rest of the series below: Week 1- The Way of Deformation: https://youtu.be/vmo56ytyhVY Additional Resources for this series: https://www.necchurch.org/portfolio/rhythms/ ----------------- For more spiritual formation content, follow Northeast Christian Church on social media. Instagram: https://www.instagram.com/northeast.church Facebook: https://www.facebook.com/NECChurch/ Online: www.necchurch.org
Stretching skulls to look more oblong has been a common practice all around the world for thousands of years across dozens of different cultures. But why did they do it? Could it be that ancient civilizations were trying to imitate the appearance of big-headed alien visitors from the past? Or did they just think it looked cool? Let's find out! Subscribe to It's Probably (not) Aliens for weekly episodes about cool ancient history! And give us a 5-star review if you have the time. It would really help us out! Suggest topics for us to tackle: http://ProbsNotAliens.com Follow the show on Twitter: https://twitter.com/ProbsNotAliens Tristan Johnson: https://StepBackHistory.com Scott Niswander: https://twitter.com/scottniswander Music by Rod Kim: https://RodKim.com Cover art by Skutch: https://twitter.com/Skutchdraws
Dimitri wonders what artificial cranial deformation is, and Linh tries her best to explain it… slowly… Check out Linh's app, Not Phở, a cook that introduces the user to Vietnamese cuisine, especially dishes other than Phở. It runs on iPhone, iPad, and Mac. It also have an iMessage sticker pack so that you can share with all your friends and family. App Store: https://apps.apple.com/app/apple-store/id1525104124?pt=14724&ct=Podcast&mt=8 Follow us on Twitter: https://twitter.com/LinhAndDimiChan Follow Dimitri on Twitter: https://twitter.com/dimitribouniol Follow Linh on Twitter: https://twitter.com/linhbouniol References: - https://en.wikipedia.org/wiki/Artificialcranialdeformation - https://www.youtube.com/watch?v=L54f8Ok1Z5w
In this episode our "hero" meets an old adversary and inspires someone to pick up a quill.
On this episode of The Grapevine, Kulja and Dylan get on the line with Walkley Award winning author and journalist, Jeff Sparrow, to break down the High Court's ruling that found Australian media outlets are responsible for defamatory comments left on their social media platforms.Then, the worst is yet to come for Australian universities following last year's 6 percent drop in revenue across the tertiary sector, Peter Hurley from the Mitchell Institute, calls in to talk about the fall out, and what these dire straits mean for Australian universities.And founder & facilitator of the Raise Our Voice Australia, Ashleigh Streeter-Jones, to discuss the campaign that's providing a voice for young Australians to have their statements read out in Parliament by MPs – and how to get involved.
Framestore's Theo Jones and Leo Hills join Ian Failes from befores & afters to discuss the studio's FIRA machine learning tech, used for the extension of proprietary simulation and rigging tools to real-time workflows.
J.R. talks with Mason King about calling, formation, deformation, and temptations.Learn more about your ad choices. Visit podcastchoices.com/adchoices