Podcasts about biological chemistry

Send us a textThis episode explores the mystery of a cellular organelle known as the vault and how unlocking the secrets of nano vaults could revolutionize Disease Cures.  Though its structure is well know and its protein composition well established, its function remains a mystery.  Joining us to explain this mystery is its discoverer, Dr. Leonard Rome.Dr. Leonard H. Rome is a cell biologist, biochemist and part-time dean involved in research, teaching and administration at the University of California, Los Angeles. He earned his undergraduate degree (B.S. in Chemistry) and graduate degrees (M.S. and Ph.D. in Biological Chemistry) at the University of Michigan, Ann Arbor. He was a postdoctoral fellow at the National Institutes of Health, where he worked on lysosome biogenesis.Dr. Rome has been on the faculty of the David Geffen School of Medicine at UCLA since he joined the Department of Biological Chemistry in 1979. He became a full Professor in 1988 and has been Senior Associate Dean for Research in the School of Medicine since 1997. Since 2005 he has been the Associate Director of the California NanoSystems Institute. Dr. Rome has served as the elected Chair of the School of Medicine Faculty Executive Committee and he is actively involved in Graduate and Medical Education. In 1991 he received a UCLA School of Medicine Award for Excellence in Education.If you would like to learn more about vaults check out Dr. Rome's youtube channel or go to our website:https:/natureandsciencepodcast.com

Sleep isn't just rest - it's your body's most extraordinary healing mechanism. Every night, regardless of what you've eaten or how you've treated your physical vessel during the day, your cells engage in a remarkable process of renewal and forgiveness. Unlike cars, phones, and other machines that deteriorate over time, we humans have this built-in reset button that allows us to wake up renewed and restored.This podcast delves deep into the contrast between pharmaceutical approaches to hormone-related conditions and nature's more balanced alternatives. Aromatase inhibitors like letrozole, commonly prescribed to postmenopausal women with hormone-sensitive cancers, come with a staggering array of side effects affecting joints, bones, cognition, and mood. Meanwhile, research from the Journal of Biological Chemistry shows that phytoestrogens from plants like soy selectively trigger beneficial estrogen receptor pathways while avoiding harmful ones - a level of sophisticated targeting that pharmaceutical options can't match.The discussion challenges numerous health misconceptions propagated by mainstream medicine. Did you know that Japanese people consuming traditional diets take in over 100 times more iodine than the FDA recommends, yet have lower cancer rates and longer lifespans? Or that wearing bras 24/7 restricts lymphatic flow and correlates with increased breast cancer risk? These inconvenient truths highlight how conventional medical wisdom often ignores or contradicts available research.Perhaps most powerful is the paradigm shift offered regarding chronic disease. Rather than viewing conditions like cancer as invaders to be bombed with aggressive treatments, we're encouraged to understand them as adaptive responses by cells to unfavorable conditions. The solution lies not in warfare but in restoration - creating an inSend us a text Join Dr. Lodi's Inner Circle membership and unlock exclusive access to webinars, healthy recipes, e-books, educational videos, live Zoom Q&A sessions with Dr. Lodi, plus fresh content every month. Elevate your healing journey today by visiting drlodi.com and use the coupon code podcast (all lowercase: P-O-D-C-A-S-T) for 30% off your first month on any membership option. Support the showThis episode features answers to health and cancer-related questions from Dr. Lodi's social media livestream on Jan. 19th, 2025Join Dr. Lodi's FREE Q&A livestreams every Sunday on Facebook, Instagram, and Tiktok (@drthomaslodi) and listen to the replays here.Submit your question for next Sunday's Q&A Livestream here:https://drlodi.com/live/Facebookhttps://www.facebook.com/DrThomasLodi/Instagramhttps://www.instagram.com/drthomaslodi/ Join Dr. Lodi's Inner Circle membership and unlock exclusive access to webinars, healthy recipes, e-books, educational videos, live Zoom Q&A sessions with Dr. Lodi, plus fresh content every month. Elevate your healing journey today by visiting drlodi.com and use the coupon code podcast (all lowercase: P-O-D-C-A-S-T) for 30% off your first month on any membership option. Learn to Thrive with ADHD Podcast Welcome to the Learn to Thrive with ADHD Podcast. This is the show for you if you're... Listen on: Apple Podcasts Spotify Join Dr. Lodi's informative FREE Livestreams...

ReferencesJournal of Biological Chemistry 2013. 28.8 52 :37355-37364 Neuro Oncol . 2020 Mar5;22(3):333-344.Front. Cell. Neurosci., 2018 27 NovemberCell Metabolism 2016. Volume 23, Issue 2, Pages 303-314JBC in Press 2025. 10854. 4April. Mydland, B. 1989. "I will Take You Home" Grateful Deadhttps://open.spotify.com/track/1Q3AmIjEbPYemA6UkjUUu0?si=3301b3057df94e04Joel, B. 1979. "Until the Night"https://open.spotify.com/track/3UzWjLQVzCG60gwJdApLqI?si=c0a9ded856c941cdSimon, P. 1965. "April Come She Will"https://open.spotify.com/track/0djZ2ndRfAL69WYNra5jRC?si=da8581de131448b2Mozart, WA. 1787. et al. Symphony 25 K.183 in G minor , plus symphonies 28, and 29https://open.spotify.com/album/3qhUJTpkFjDeM49QidGMQb?si=iUpvUWNfSlyWGSzgvjDKLg

“I didn't set out to be an entrepreneur, but when I couldn't find a company doing what I believed in, I built my own.” In part two of our conversation with Kate Yen, Founder and CEO of Auron Therapeutics, we explore her journey from leading a novel cancer therapy program at Agios to founding her own biotech company. Kate shares insights into drug development, clinical trials, and the business of biotech, highlighting the importance of translational biology, strategic partnerships, and lean operations in building a successful biotech startup. Kate earned her Ph.D. in Biological Chemistry from UCLA, where she also completed her postdoc. Before Auron, she held roles at Merck and as a UCLA professor before joining Agios Pharmaceuticals, where she led the IDH translational research team behind two FDA-approved IDH mutant inhibitors and co-led the discovery of vorasidenib, a promising glioma therapy now in clinical development.

La deshidratación crónica leve es una epidemia, se calcula que hasta el 55% de la población joven puede padecerla. Es una condición con frecuencia pasada por alto y que tiene serios efectos negativos sobre la cognición, la salud cardiovascular, gastrointestinal, articular, entre otros. En este episodio explicamos de qué se trata la deshidratación crónica leve, los efectos que produce, cómo detectarla y cómo prevenirla.Enlaces a nuestras redes sociales:Instagram⁠⁠⁠@brainfulnesspod⁠⁠⁠⁠⁠⁠@ladoctoraneuro⁠⁠Youtube⁠⁠@brainfulness⁠⁠Twitter/X⁠⁠⁠@brainfulness⁠pod⁠⁠Página web⁠⁠www.brainfulnes.life⁠⁠Blog⁠⁠https://brainfulness.life/blogReferencias bibliográficasMitchell, H. H., Hamilton, T. S., Steggerda, F. R., & Bean, H. W. (1945). The chemical composition of the adult human body and its bearing on the biochemistry of growth. Journal of Biological Chemistry, 158(3), 625-637.Maroudas A. Fluid transport in cartilage. Ann Rheum Dis. 1975 Dec;34 Suppl 2:Suppl 77-81. PMID: 25330584.Kenney, E. L., Long, M. W., Cradock, A. L., & Gortmaker, S. L. (2015). Prevalence of inadequate hydration among US children and adolescents: A population-based analysis. Journal of the Academy of Nutrition and Dietetics, 115(6), 943-951.Valtin H. "Drink at least eight glasses of water a day." Really? Is there scientific evidence for "8 x 8"? Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R993-1004. doi: 10.1152/ajpregu.00365.2002. PMID: 12376390.Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS. Hydration and Performance. Sports Science Exchange. 2007;20(2):1-5.Benton D, Burgess N. The effect of the consumption of water on the memory and attention of children. Appetite. 2009;53(1):143-6.Benton D, Young HA. Reducing calorie intake may not help you lose body weight. Perspect Psychol Sci. 2017;12(5):703-714. (Nota: Este es un ejemplo más reciente; el estudio de 2016 mencionado en la respuesta no es accesible, así que se proporciona esta alternativa.)Palma L, Tavares L, Santos O, et al. Dietary water affects human skin hydration and biomechanics. Clin Cosmet Investig Dermatol. 2015;8:413-21.Dennis EA, Dengo AL, Comber DL, et al. Water consumption increases weight loss during a hypocaloric diet intervention in middle-aged and older adults. Obesity (Silver Spring). 2010;18(2):300-7.Manz F, Wentz A. The importance of good hydration for the prevention of chronic diseases. Nutr Rev. 2005;63(6 Pt 2):S2-S5.Dennis EA, Dengo AL, Comber DL, et al. Water consumption increases weight loss during a hypocaloric diet intervention in middle-aged and older adults. Obesity (Silver Spring). 2010;18(2):300-7.Boschmann M, Steiniger J, Hille U, et al. Water-induced thermogenesis. J Clin Endocrinol Metab. 2003;88(12):6015-9.Shirreffs SM, Maughan RJ. The effect of alcohol on athletic performance. Curr Sports Med Rep. 2006;5(4):192-6.Sawka MN, Burke LM, Eichner ER, et al. American College of Sports Medicine position stand. Exercise and fluid replacement. Med Sci Sports Exerc. 2007;39(2):377-90.Jeukendrup AE, Currell K. Should energy drinks be banned from sport? Int J Sport Nutr Exerc Metab. 2008;18(5):519-29.Rehrer NJ, Brouns F, Beckers EJ, et al. Physiological changes and gastro-intestinal symptoms as a result of ultra-endurance running. Eur J Appl Physiol Occup Physiol. 1992;64(1):1-8.Rosner MH, Kirven J. Exercise-associated hyponatremia. Clin J Am Soc Nephrol. 2007;2(1):151-61.Hew-Butler T, Ayus JC, Kipps C, et al. Statement of the Second International Exercise-Associated Hyponatremia Consensus Development Conference, New Zealand, 2007. Clin J Sport Med. 2008;18(2):111-21.Ayus JC, Arieff A. Pathogenesis and prevention of hyponatremia. Endocrinol Metab Clin North Am. 1993;22(2):437-49.

Part 1 of 2: Our guest today is Kate Yen, Founder and CEO of Auron Therapeutics. Auron Therapeutics leverages cutting-edge science and AI-powered analysis to develop next-generation cancer therapies by mapping key drivers of tumorigenesis. Kate earned her Ph.D. in Biological Chemistry from UCLA, where she also completed her postdoc. She held roles at Merck and as a UCLA professor before joining Agios Pharmaceuticals, where she led the IDH translational research team behind two FDA-approved IDH mutant inhibitors and co-led the discovery of vorasidenib, a promising glioma therapy now in clinical development. With deep expertise in preclinical and clinical research, a proven track record in advancing breakthrough therapies, and a passion for oncology, Kate's journey and insights are invaluable.

The launch of Girls in SciTech in Luxembourg last week is a movement aimed at empowering girls to pursue careers in Science, Technology, Engineering & Maths. The Girls in SciTech campagin, coordinated by Professor Serge Haan, brought together high school students, university alumni, industry professionals, and political leaders, all united to tackle the gender imbalance in STEM fields. How can we encourage more young female minds to take up the ‘hard' sciences rather than just the ‘soft' sciences (life sciences, medicine, biological sciences etc.)? Indeed one can even question the words attributed to the sciences here.  The State of Women in STEM: A Statistical Snapshot Despite incremental progress, women remain underrepresented in STEM, particularly in senior roles. According to Eurostat, 41% of all scientists and engineers in the European Union were women in 2022. The figures are consistently lower for maths, physics, computer science and engineering, varying from country to country.  Philippe Hiligsmann, Vice-Rector for Academic and Student Affairs at the University of Luxembourg, underscored the importance of the campaign: “This is more than an event; it is a movement to change things by motivating and inspiring girls to pursue a career in science.”  A Powerful Group of Role Models The event featured a panel of inspiring women from diverse STEM backgrounds, who shared their own personal journeys and ideas: - Hania Tayara, Programme Leader at Native Scientists - Marie-Alix Dalle, Environmental Engineer at ArcelorMittal - Prof. Serge Haan, Full Professor in Biological Chemistry, University of Luxembourg - Laurence Lampecco, Analyst Developer at POST Luxembourg - Prof. Skerdilajda Zanaj, Full Professor in Economics, University of Luxembourg - Marie-Louise Uwizeye, Chargée d'études at Administration de la gestion de l'eau - Monika Zlopasa, Investment Fund Risk Manager at UBS Luxembourg Stéphanie Obertin, Minister for Research and Higher Education in Luxembourg, captured the essence of the event's message when she said, “It's about transforming our society by empowering women in STEM fields. The unique perspectives and ideas they bring to the field enhance problem-solving and spark innovation.” The Challenges: What's Holding Girls Back? The panelists identified several key barriers that contribute to the gender gap: Stereotypes and Gender Roles:  From an early age, girls are exposed to stereotypes that suggest STEM is not for them. Many girls are told, either overtly or subtly, that they are not as good at math or science as boys. These messages, often reinforced by parents, peers, and teachers, can impact their self-confidence and limit their aspirations. As Prof. Skerdilajda Zanaj pointed out, “It's not that girls don't like science, it's that they are taught to believe it's not for them.” Lack of Role Models:  The absence of female role models in STEM fields further discourages girls from pursuing these paths. Research shows that girls are more likely to enter STEM fields if they see women succeeding in them. “For every 10 Google queries asking, ‘Is my daughter gifted?' there are 25 asking, ‘Is my son gifted?'” said Marie-Alix Dalle, an alumna of the University of Luxembourg and an Environmental Engineer at ArcelorMittal. The lack of female role models in leadership positions can make it harder for girls to imagine themselves succeeding in science. Parental Biases:  Parents often unconsciously reinforce gendered expectations. Research has shown that girls are less likely to be encouraged to pursue STEM subjects, particularly in math and technology. This parental influence can have long-term effects on girls' academic choices and self-perception. Workplace and Family Balance:  Women in STEM often face the additional challenge of balancing their careers with family life. Marie-Louise Uwizeye, an engineer and mother of three, shared her experience of working in engineering while raising children: “If you really want to do it, you can. I am a mother of three children, I have a PhD, and I am working full-time. Don't excuse yourself—this is your right.” Despite the challenges, she emphasized that women can thrive in STEM, even as mothers. Breaking the Barriers: Solutions and Strategies To address these barriers, the panelists discussed various strategies that can help increase the number of girls in STEM, especially in leadership positions: Increased Representation of Women in Senior Roles:  One of the critical points raised during the discussion was the importance of seeing women in senior positions within STEM fields. Not only do these role models inspire the next generation, but they also demonstrate that leadership in STEM is achievable for women. “We need to increase the representation of women in science at senior levels to show young girls that it's possible to rise to the top,” said Hania Tayara. Studies show that having female mentors or professors increases the likelihood that girls will continue to pursue STEM studies and careers. Changing Course Content:  Many panelists emphasized the importance of making STEM content more relevant to girls. As Marie-Alix Dalle put it, “Enough talk about cars!” In order to engage more girls, science education must reflect a broader range of interests and real-world applications. “Science should resonate with girls as well,” she added, advocating for curricula that connect STEM to real-world issues like climate change, healthcare, and technology. Mentorship and Support Networks:  Several initiatives are already in place in Luxembourg to support girls in STEM. For example, mentorship programs, such as those offered by Native Scientists and the University of Luxembourg, help guide girls through the uncertainties they may face when applying to university or entering STEM fields. Laurence Lampecco, an analyst developer at POST Luxembourg, shared her personal experience of mentorship and the crucial role it played in her journey: “Having someone who believes in you makes all the difference.” Challenging Societal Norms:  Finally, the discussion underscored the importance of challenging the societal norms that dictate what careers are “appropriate” for men and women. By showcasing the success stories of women in STEM, through media and other platforms, we can shift perceptions and inspire young girls to see these fields as viable career paths. As Monika Zlopasa, a Risk Manager at UBS Luxembourg, pointed out, “We miss out on complementary skills and points of view when we don't have women in STEM. It's not just about representation—it's about making work better, more innovative, and more inclusive.” Moving Forward: A Collective Effort The Girls in SciTech event marked an important milestone in the effort to close the gender gap in STEM. But as the panelists emphasized, real change requires a collective effort from all sectors of society. From parents and teachers to industry leaders and policymakers, everyone has a role to play in creating a more inclusive environment for girls in STEM. Yuriko Backes, Luxembourg's Minister for Gender Equality and Diversity, stated, “When young girls see women excelling in STEM fields, it serves as an inspiration. It shows them that they too can achieve success in these areas.” By continuing to promote mentorship, support networks, and initiatives like Girls in SciTech, we can ensure that the next generation of STEM leaders includes a balanced representation of both women and men. In the end, the journey towards gender equality in STEM is just beginning. With sustained commitment, collaboration, and advocacy, we can create a world where girls in science are not the exception—but the norm.

This week we welcome Chris Laszcz-Davis - OHTA, Chelsea Earhart – BGC, Larry Sloan – AIHA and Dr. Albert Tien -WHWB-US to talk about global worker health and the new Global Pathway for CIH Accreditation. This week we focus on organizations involved in global worker safety and their new collaboration for educating and mentoring global EH&S professionals. We discuss how someone with no specific education, such as a degree in engineering, can become a CIH through the program. It starts with the training from OHTA; work experience with WHWB-US in places that are in need of help with health and safety; proceeds to membership in AIHA, along with participation in committees, etc.; and concludes with an application and a test to obtain a CIH accreditation. Chris Laszcz-Davis, MS, CIH, FAIHA, FAIC is the Founder & President of The Environmental Quality Organization (EQO) LLC, She has over forty (40) years of executive management including as a former Corporate Vice-President, Environmental Affairs for Kaiser Aluminum & Chemical Corporation. Prior to industry, Chris worked for the US Department of Energy (DOE) in both DC and the west coast as a regional EH&S Manager and at the University of California Lawrence Livermore National Laboratories. Chris is presently Co-Chair of the global Occupational Hygiene Training Association (OHTA). Chelsea Earhart, MBA, CAE, ICE-CCP is the Executive Director of The Board for Global EHS Credentialing (BGC®). Over the past 22 years, Chelsea Earhart has served as the certification / accreditation departments of associations representing diverse professions and industries. She has also helped many certification and licensure organizations create and implement exams and examination programs. Lawrence Sloan serves as CEO of the American Industrial Hygiene Association (AIHA). Before this, he served as CEO at SOCMA, a trade association representing the US specialty chemical industry. He began his career as a chemical engineer at Air Products. Mr. Sloan earned a BS in chemical engineering from the University of Pennsylvania and an MBA from Northwestern University's Kellogg School of Management. Dr. Albert Tien is the Managing Partner for 2TSustainAbility. He is also President and one of the founding members of Workplace Health Without Borders (US). Dr. Tien holds a PhD Biotechnology from Swiss Federal Institute of Technology; he also was a Postdoctoral Fellow at Oakridge Institute for Science and Engineering. His MS Life Sciences is from New Mexico Highlands University and his undergraduate work was at Tulane University in Biological Chemistry.

“Cell division is fundamental to the growth of every living thing and when it goes wrong and is out of control this is the basis for all cancers and understanding this process is important,” explained Sir Paul Nurse. When it comes to understanding the fundamentals of cell division and the cancer connection, Sir Paul is a world-renowned expert and pioneer. He was awarded the Nobel Prize in Physiology or Medicine in 2001. In this podcast, he explained the ideas that sparked his ground-breaking research and how his findings gave scientists around the world the insight and tools they needed to develop advanced cancer therapeutics such as immunotherapy. Sir Paul is adept at explaining his work and the complexities of science in easy-to-understand language, combined with his keen intellect, modesty and a warm sense of humor. He's someone you will enjoy spending time with. As a young scientist, Sir Paul said he knew there would be a lot of ups and downs, and he was determined “to study something important and what is more fundamental than the process that is the basis of all growth … I didn't do this to cure cancer, but to understand the principles behind dividing cells and I thought by understanding this it would have implications for cancer and other diseases.” Sir Paul, director and chief executive of the Francis Crick Institute in London, was recently in Columbus as the recipient of the 26th Annual Herbert and Maxime Block Memorial Lectureship Award for Distinguished Achievement in Cancer. In addition to delivering a lecture, the Block Lectureship includes a mentor/mentee collaboration between Sir Paul and Li-Chun Tu, PhD, an Ohio State and OSUCCC-James assistant professor in the Department of Biological Chemistry and Pharmacology. Dr. Tu joined the second half of this podcast, and described her work in genetics. Sir Paul and Dr. Tu look forward to working together. “I truly believe he will give me such good advice,” Dr. Tu said.

This week on The Rock the Ripple Podcast, we catch up with Specialist Fertility Coach, Embryologist, Andrologist & Chemist with a Bachelor of Science majoring in Chemistry, Biochemistry and Biological Chemistry with over 25 years of experience across all areas of IVF and Fertility treatments, Sophia Baseotto. Sophia is also the host of the “Let's Talk IVF' Podcast and is trained in Cognitive Behavioural Therapy, Hypnosis, Neuro Linguistic Programming and Time Line Therapy ™. After working with over 10,000 clients, this week's guest uses both science and modern coaching techniques to provide people with positive results and successful outcomes. We covered so much ground in this incredible chinwag and I hope you enjoy it as much as we did! // Connect with Sophia at these places: ▸ Website: www.ivfcoachingclinic.com.au   ▸ Podcast: https://itunes.apple.com/au/podcast/lets-talk-ivf/id1415216739 ▸ Instagram: https://www.instagram.com/ivfcoachingclinic/ ▸ Facebook: https://www.facebook.com/ivfcoachingclinic/ ▸ Bookings: https://ivfcoachingclinic.as.me/intro // Connect with Nereeda at these places: ▸ Shift Club is here! Are you in? Click the link below for all the details

A new study shows that a high-fat diet suppresses the expression of a protein called Jak3, which causes a cascade of inflammation that starts in the intestine, moves through the liver and on to the brain, ultimately causing Alzheimer's-like symptoms. Listen in this week as Dee discusses the results of this study and what it means for your health.References:Kumar, N., Mishra, J., Morales, R., & Kumar, P. (2024). Kinases in Gut-Liver-brain communication and neuroinflammation. Journal of Biological Chemistry, 300(3), 106750. https://www.jbc.org/article/S0021-9258(24)01223-7/fulltext

References Gastroenterology. 2023 Feb;164(2): 256–271.e10. The Journal of Biological Chemistry 2018  293, 19001-19011 Leitch, D. 1965 "Catch the Wind" https://youtu.be/J8hjEYTpwE8?si=VfSaLDcP5JxzzP-p Hendrix, J. 1967. "The Wind Cries Mary" https://youtu.be/ARO2vbGFLJM?si=_IIEFN0BOEy6DfqW Bach, JS. 1717. Partita in D Minor, BWV 1004 https://youtu.be/qtyTaE7LvVs?si=q7Xe7rnzDBbEx-xc --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Heute in den Wissensnachrichten: +++ Kaffeemischung von KI zusammengestellt +++ Neue detailliertere Mondkarte veröffentlicht +++ E-Bike-Unfälle führen oft zu gravierenden Kopfverletzungen +++**********Weiterführende Quellen zu dieser Folge:China's Moon atlas is the most detailed ever made, Nature, 25.04.2024Cranio-cervical and traumatic brain injury patterns-do they differ between electric bicycle, bicycle, and motorcycle-induced accidents?, European Journal of Trauma and Emergency Surgery, April 2024Performance errors during rodent learning reflect a dynamic choice strategy, Current Biology, 26.04.2024StIx Report: The World of States in 2023 (pdf), 29.04.2024Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor, Journal of Biological Chemistry, April 2024**********Ihr könnt uns auch auf diesen Kanälen folgen: Tiktok und Instagram.

Metabolism has a direct impact on aging and the way we look. On today's episode, we discuss the current research around metabolism with experts Dr. Heather Christofk and Dr. Navdeep Chandel and dive into hair follicle stem cell activation, a lesson on hyaluronic acid from naked mole rats, and the complexity of addressing oxidative stress and the skin's extracellular matrix.Heather Christofk, Ph.D., is a Professor of Biological Chemistry at UCLA's David Geffen School of Medicine and a director at the Jonsson Comprehensive Cancer Center. Her research focuses on the role of metabolism on cancer and virus infections. She is co-founder of Pelage Pharmaceuticals, a company developing new drugs to treat baldness that activate hair follicle stem cells by changing their metabolism. She earned a bachelor's degree at UCLA and a Ph.D. at Harvard University.Navdeep Chandel, Ph.D., is the David W. Cugell, MD, Distinguished Professor of Medicine, Biochemistry, and Molecular Genetics at Northwestern University. His research focuses on metabolism and mitochondrial signaling, particularly as it relates to cancer biology, the immune system, neuroscience, and aging. He's the author of Navigating Metabolism. He earned his bachelor's degree and Ph.D. in cell physiology at the University of Chicago. Dr. Chandel received the 2023 Lurie Prize in Biomedical Sciences by the Foundation for the National Institutes of Health.(01:45) – Introducing Dr. Heather Christoff and Dr. Nadi Chandel(05:51) – Crossing paths(09:15) – Drawn to metabolism and cell signaling(12:43) – Hair follicle stem cells(18:50) – Therapeutic potential(32:59) – Other tissue stem cells(34:43) – Hyaluronic acid(39:49) – Reactive oxygen species(47:44) – Cancer and ferroptosis(51:30) – Skin aging(57:06) – Mitochondrial functionIf there are topics that you are interested in learning more about, please visit MichaelJLeeMD.com.If you'd like to receive new episodes as they're published, please follow I'd Love to Know in Apple Podcasts, Spotify, or wherever you get your podcasts. If you enjoyed this episode, please consider leaving a review on Apple Podcasts or Spotify. It really helps others find the show.The information from this podcast does not constitute medical advice and is meant for basic informational purposes only. If you're interested in pursuing any of the therapies, supplements, or medications discussed here, please consult with your physician.Podcast episode production by Dante32.

Alex and Ryan review some practical insights from Marc Milstein, PHD. Dr. Marc Milstein is a leading scientific researcher on neuroscience, health, and happiness. His insights provide science-based solutions to keep the brain healthy, lower the risk of dementia, boost productivity and maximize longevity. He earned both his Ph.D. in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA. Dr. Milstein's new book “The Age-Proof Brain” has been a #1 best seller on Amazon in several categories, including, Aging, Longevity, and Neuroscience.It is important to keep our mind and body strong especially as we age. They review top 10 points.https://www.hartfordfunds.com/insights/investor-insight/client-seminars/retain-your-brain/10-brain-tips-to-help-keep-your-brain-healthy-as-you-age.html 

Folge ansehen oder anhören auf YouTube I Apple Podcasts I SpotifyWir sprechen über:Wie Fruktose weit über die Rolle eines einfachen Zuckers hinausgeht und entscheidende Prozesse in unserem Körper beeinflusst.Wir besprechen, wie Fruktose im Körper verstoffwechselt wird und warum dies für die Entstehung von Übergewicht und metabolischen Erkrankungen relevant ist.Warum Fruktose in der Natur als zentraler Signalgeber wirkt und den Überlebensmechanismus aktiviert und wie dieser Mechanismus in der modernen Welt zu gesundheitlichen Herausforderungen führt.Danke an die WerbepartnerEss-Wissen Club für PraktikerDein Schlüssel zu aktuellem Ernährungswissen und Vorlagen für die PraxisBleibst Du gerne auf dem Laufenden, ohne in Studienbergen zu versinken? Der EWiP-Club ist Deine Lösung! Wir filtern, übersetzen und kondensieren die neuesten Ernährungserkenntnisse direkt auf Deinen Schreibtisch - in deutscher Sprache und praxisnah aufbereitet.14 Tage ohne Risiko testen. Rabatt-Code PODCAST10 und du bekommst 10% auf die Jahresmitgliedschaft.https://esswissen-club.com/Kapitel00:00 Einleitung - worum geht es in der Episode 01:51 Vorstellung EssWissen Club - Vorlagen für die Praxis 04:45 Fruktose als zentraler, evolutionärer Mechanismus 05:46 Besprechung der Forschungen und Konzepte von Dr. Richard Johnson über die Rolle von Fructose und Übergewicht. 10:00 Erläuterung des Stoffwechselwegs von Fructose und wie sie die Energiegewinnung beeinflusst. 11:20 Diskussion über die evolutionäre Bedeutung von Fruktose und ihren Einfluss auf den Überlebensmechanismus. 13:41 Die unterschiedlichen Effekte von Harnsäure auf intrazelluläre und extrazelluläre Prozesse im Körper. 15:40 Effekte der Fruktoseaufnahme auf dsa Gehirn 18:34 Fruktose in Haushaltszucker und Honig 19:05 Dauerhafte Aktivierung der Fruktose-Enzymschritte führt zu Überaktivierung 21:57 Die Notwendigkeit einer vereinenden Theorie, um die verschiedenen Erklärungsmodelle für Adipositas zu integrieren. 26:12 Die Verbindung von Psyche und StoffwechselAlles über Ulrike Gonder und Julia TulipanÜber Ulrike Gonder: Dipl. oec. troph. und Freie Wissenschaftsjournalistin https://ulrikegonder.de/Über Julia Tulipan: Magister der Biologie und Master klinische Ernährungsmedizin https://juliatulipan.com/Relevante ArtikelDr. Richard Johnson MD:https://drrichardjohnson.com/Hüftgold und Winterspeck - vom Evolutionsvorteil zur Fettfalle: Wie wir unsere Gene überlisten, um schlank zu werden und es auch zu bleiben https://amzn.to/4bVb5vFNature Wants Us to Be Fat: The Surprising Science Behind Why We Gain Weight and How We Can Prevent--and Reverse--It https://amzn.to/4bEfgM3https://drrichardjohnson.com/researchpublications/Johnson, Richard J., et al. "The fructose survival hypothesis for obesity." Philosophical Transactions of the Royal Society B 378.1885 (2023): 20220230.Johnson, Richard J., Laura G. Sánchez‐Lozada, and Miguel A. Lanaspa. "The fructose survival hypothesis as a mechanism for unifying the various obesity hypotheses." Obesity 32.1 (2024): 12-22.Lanaspa, Miguel A., et al. "Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome." Nature communications 4.1 (2013): 2434.Lanaspa, Miguel A., et al. "Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver." Journal of Biological Chemistry 287.48 (2012): 40732-40744.Febbraio, Mark A., and Michael Karin. "“Sweet death”: fructose as a metabolic toxin that targets the gut-liver axis." Cell metabolism 33.12 (2021): 2316-2328.Todoric, Jelena, et al. "Fructose stimulated de novo lipogenesis is promoted by inflammation." Nature metabolism 2.10 (2020): 1034-1045.Danke an die Werbepartner, ohne deren Unterstützung dieser Podcast nicht möglich wäre.Dein Schlüssel zu aktuellem Ernährungswissen und Vorlagen für die Praxis Bleibst Du gerne auf dem Laufenden, ohne in Studienbergen zu versinken? Der EWiP-Club ist Deine Lösung!Wir filtern, übersetzen und kondensieren die neuesten Ernährungserkenntnisse direkt auf Deinen Schreibtisch - in deutscher Sprache und praxisnah aufbereitet.Zeitsparend und PraxisorientiertWir wissen, Deine Zeit ist kostbar. Deshalb bietet Dir EWiP einen schnellen Überblick über essentielle Studienergebnisse. Verbringe weniger Zeit mit Recherche und mehr mit dem, was wirklich zählt: Deinen Patienten, Kunden und Coachees.Werkzeuge für Deinen ErfolgMit EWiP erhältst Du nicht nur Wissen, sondern auch die Werkzeuge, um es effektiv zu teilen. Fertige Powerpoint-Folien zu Schlüsselstudien, übersichtliche Factsheets und einprägsame Infografiken machen Deine Präsentationen und Beratungen zum Kinderspiel.Vernetzung und AustauschNutze unsere regelmäßigen Live-Sessions für einen wertvollen Austausch mit Kollegen und Experten. Stelle Fragen, diskutiere mit und bringe Deine Anliegen ein - im EWiP-Club bist Du Teil einer aktiven Gemeinschaft von Praktikern.Für Wen?EWiP ist für alle, die im Ernährungsbereich arbeiten und sich fragen: Wie halte ich Schritt mit der Flut an neuen Studien? Wie integriere ich aktuelle Erkenntnisse in meinen Arbeitsalltag, ohne dabei den Überblick zu verlieren? EWiP ist Deine Antwort.Schließe Dich uns anWerde Teil von EWiP und erlebe, wie wir Dir Arbeit abnehmen, Dich stets informiert halten und einen Raum für professionellen Austausch bieten. EWiP - wo Praxis auf Wissen trifft.14 Tage ohne Risiko testen. Rabatt-Code PODCAST10 und du bekommst 10% auf die Jahresmitgliedschaft.https://esswissen-club.com/ Bitte beachten Sie auch immer den aktuellen "Haftungsausschluss (Disclaimer) und allgemeiner Hinweis zu medizinischen Themen" auf https://juliatulipan.com/haftungsausschluss/

Cholsoon Jang, PhD is an Assistant Professor of Biological Chemistry at the University of California Irvine School of Medicine. Dr. Jang obtained bachelor's and master's degrees from Korea Advanced Institute of Science and Technology. He then received PhD from Harvard University and completed postdoctoral training at Princeton University. Dr. Jang's laboratory focuses on understanding how dietary nutrients are processed in the body and exert health-beneficial or detrimental effects. Dr. Jang received prestigious awards such as Pinnacle Research Award from the American Association for the Study of Liver Disease and Edward Mallinckrodt Jr. Foundation Award, and several research grants from National Institute of Health. Dr. Jang has published 92 papers in prominent journals like Nature, Cell, and Science, which are cited over 8500 times. Dr. Jang is regularly invited to speak nationally and internationally on his research in nutrient metabolism. In this episode we discuss:What's the difference between fructose and glucose?The factors that affect your ability to metabolize fructose.The problems with current nutritional research.Should you be eating sugar?The Jang lab at UC IrvineMentioned in this episode:Get 10% off your first boxhttps://takethesis.com/drlyon/20% off your first orderhttps://trybite.com/DRLYONVisit 1st Phorm Website for Free Shipping on orders $75+http://www.1stphorm.com/drlyonInside Tracker 20% Off the Entire Storehttps://info.insidetracker.com/drlyonGet your free LMNT Sample Pack with any purchasehttps://drinklmnt.com/drlyon

Episode 9 of the DNA Papers discusses a set of papers by the first scientist who made a sustained effort into uncovering the secret behind specificity of nucleic acids. The principle author, Erwin Chargaff, a European-American biochemist from Columbia University in New York, determined that the relative rations of the four nucleotide bases—A, T, G and C—were not present in all DNA in equal amounts as widely assumed, but rather, that they varied in proportion from one to another, with the amount of the A and G bases being equal to the T and C bases respectively. Furthermore, he also demonstrated that the ratio of these amounts was specific and consistent for a given species. He first laid out his vision for determining the role of nucleic acids in 1947, and over the next decade or so, proceeded to probe the finer details of DNA chemistry with the then state-of-the art innovations in techniques such as chromatography and UV spectroscopy. Papers discussed include: Chargaff, Erwin. “On the Nucleoproteins and Nucleic Acids of Microorganisms.” Cold Spring Harbor Symposia on Quantitative Biology 12 (January 1, 1947): 28–34. https://doi.org/10.1101/SQB.1947.012.01.006. Vischer, Ernst, and Erwin Chargaff. “The Separation and Quantitative Estimation of Purines and Pyrimidines in Minute Amounts.” Journal of Biological Chemistry 176 (1948): 703–14. Chargaff, Erwin. “Chemical Specificity of Nucleic Acids and Mechanism of Their Enzymatic Degradation.” Experientia 6, no. 6 (June 15, 1950): 201–9. Joining us to illuminate the role of Chargaff and his experiments in the history of DNA are: Pnina Abir-Am, Brandeis University Kersten Hall, University of Leeds Hans-Jörg Rheinberger, Max Planck Institute for the History of Science View more at https://www.chstm.org/video/144 Recorded August 9, 2023.

Episode 151 of the Fit Father Project Podcast is about brain health, improving memory, protecting immunity, and fighting dementia.In this episode, you'll meet Dr. Marc Milstein, who earned a Ph.D. in Biological Chemistry and a Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA, has researched cancer biology and neuroscience, and has been published in multiple scientific journals. You've probably heard a lot lately about fixing gut health to promote longevity, but many people overlook their real superpower: brain health. According to Dr. Milstein, our power to improve brain function lies in the brain's connection with the rest of the body. This means that various lifestyle factors governed by the brain, such as sleep habits and environmental toxins, tend to impact our health more than we realize. His book, The Age-Proof Brain, covers each of these topics and offers integrative, science-supported strategies to increase memory, fight off depression, improve mood, ignite energy, and even prevent dementia and non-genetic Alzheimer's. Dr. Milstein's mission is to educate and empower everybody to take control of their brain health to maximize longevity and reduce the risk of illness. It's a fantastic and informative conversation, and Dr. Milstein makes all this complex stuff easily digestible and understandable so we can all live long, healthy, and happy lives!In this episode, you'll learn about: How brain health affects body health.Why embracing getting older can make aging more manageable and less painful.Small lifestyle changes that can have significant impacts.The differences between Alzheimer's and dementia.The causes of common aging issues and what you can do about them.Tips for optimizing nutrition, exercise, sleep, and more.How to train your brain. And so much more!So, if you want to get the most from your health and fitness efforts, listen to this episode on brain health, take some notes, and check out FF30X! More From Dr. Milstein:Dr. Milstein's WebsiteThe Age-Proof BrainDr. Milstein on YouTubeDr. Milstein on InstagramDr. Milstein on FacebookDr. Milstein on LinkedInWhat is FF30X?FF30X is a simple, sustainable, and specific weight loss program designed especially for busy men over 40. With short metabolic training workouts, an easy-to-follow meal plan, and an accountability team there for you at every step, FF30X can help you lose 30, 40, or even 50+ lbs — even if you've never picked up a weight in your life. Click here to see what you get when you join...

Simay Okyay McNutt, MPH is a Health Policy and Reimbursement Consultant. She manages device and medtech clients and consults them on coding, coverage, and payment issues, with specialization in Medicare. She conferred a Bachelor in Biological Chemistry and Bachelor in Women, Gender, & Sexuality at the University of Virginia. She then worked as a certified medical assistant before getting her Master of Public Health at The George Washington University - Milken Institute School of Public Health.Simay Okyay McNutt, MPH on LinkedIn: https://www.linkedin.com/in/simayokyay/Join 750+ member email blasts: http://thephmillennial.com/signupSupport The Public Health Millennial: https://ko-fi.com/thephmillennialChapters:@0:00 Episode Start@2:12 Simay Okyay McNutt, MPH Intro@2:50 Identify and personal background@5:30 Importance of Health Policy in Public Health context@8:26 What is public health?@11:57 Bachelors in Biological Chemistry & Women, Gender, & Sexuality at University of Virginia@15:40 Experiences during Undergrad + Takeaways@21:48 Certified Medical Assistant at Clifton Care@26:45 Board positions@32:57 Master of Public Health at The George Washington University in health policy@38:25 Experiences during MPH@42:54 Getting full time Health Policy Associate position@45:28 Master of Public Health takeaways@47:37 Senior Health Policy Associate and then Manager at Applied Policy@49:50 Getting good at your hob@58:40 Developing med technology expertise@1:02:55 Connect & Future Predictions@1:04:49 The Furious FiveSupport the showThanks for tuning in. Let's all work together towards a culture of health, wellbeing, and equity for all. ⭐⭐ SUBSCRIBE & Leave a 5-STAR REVIEW! ⭐⭐ Follow & Support:- Contribute to the show (one-time or monthly)- The Public Health Millennial on IG - The Public Health Millennial on LinkedIn - The Public Health Millennial Website- Omari Richins, MPH on LinkedIn- Support on The Public Health Store

In the pursuit of understanding the fascinating complexities of our brains and unraveling the secrets to a healthier, happier life, I am delighted to have the opportunity to engage in an eye-opening conversation with Dr. Marc Milstein!  With an impressive background in Biological Chemistry and a degree from UCLA in molecular, cellular, and developmental biology, Dr. Milstein's expertise lies in distilling cutting-edge scientific research on health and happiness into captivating presentations that entertain, educate, and empower his audience to live better.  In today's discussion, we delve into a myriad of intriguing topics ranging from the astonishing anatomy of sorry and the mesmerizing intricacies of our brains' physiology to the pivotal role of neuroplasticity and the detrimental effects of plaques and tangles. We explore how waste build-up impacts our focus, productivity, and energy, and we uncover the factors influencing brain health, including the crucial interplay between a robust immune system and the intriguing link between leaky gut and memory issues. We also tackle the distinctions between mild cognitive impairment, dementia, and Alzheimer's disease, examining the impact of insulin resistance and trauma while seeking actionable ways to age-proof our most precious organ.  I invite you to join Dr. Milstein and me as we embark on the enthralling journey of discovering the keys to unlocking the full potential of our minds and enriching our lives as we unravel the mysteries of our most vital organ. Stay tuned as we explore ways to age-proof our brains while gaining invaluable insights into enhancing focus, productivity, and energy! IN THIS EPISODE YOU WILL LEARN: The role of lifestyle factors on brain health.  The importance of learning new things.  How to cross-train your brain.  The interrelationship between the brain and immune system.  The importance of sleep and gut health.  How the dopamine squirt pertains to memory.  Signs of mild cognitive impairment.  Hearing loss and the role of hormones.  Metabolic health and brain health.  The importance of sleep and the brain.  The role of exercise in brain health.  About Dr. Marc Milstein Dr. Marc Milstein specializes in taking the leading scientific research on health and happiness and presents it in a way that entertains, educates, and empowers his audience to live better.  His presentations provide science-based solutions to keep the brain healthy, lower the risk of dementia, boost productivity, and maximize longevity. He earned his Ph.D. in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA.  Dr. Milstein has conducted research on topics including cancer biology and neuroscience, and his work has been published in multiple scientific journals. Dr. Milstein has been quoted breaking down and analyzing the latest research in popular press such as USA Today, Huffington Post, and Weight Watchers Magazine. Dr. Milstein has also been featured on television explaining the latest scientific breakthroughs that improve our lives. Dr. Milstein's upcoming book "The Age-Proof Brain" will be published on October 25th, 2022. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia's website Connect with Dr. Marc Milstein On his website On Instagram  On social media: @drmarcmilstein.com Dr. Milstein's book, The Age-Proof Brain: New Strategies to Improve Memory, Protect Immunity, and Fight Off Dementia

Dr. Weizhe Hong is a Professor of Neurobiology, Biological Chemistry, and Bioengineering at the University of California Los Angeles. His research aims to uncover the fundamental neural mechanisms underlying social behavior, with a specific focus on empathy and prosociality. Dr. Hong earned his Ph.D. degree in 2012 from Stanford University and was a Helen Hay Whitney Postdoctoral Fellow at the California Institute of Technology during 2012-2015. In 2016, he joined UCLA as Assistant Professor, and he was promoted to Associate Professor with tenure in 2020 and to Full Professor in 2023. He is also the recipient of a Young Investigator Award from the Society for Neuroscience, an Early Career Award from the Society for Social Neuroscience, a Mallinckrodt Scholar Award, a Vallee Scholar Award, a Searle Scholar Award, a Packard Fellowship in Science and Engineering, a McKnight Scholar Award, a Klingenstein-Simons Fellowship, and a Sloan Research Fellowship.​Link: A Multi-Brain Framework for Social InteractionLink: Neural Basis of Prosocial Behavior

Today on Sense of Soul Podcast we have Dr. Marc Milstein, he is brain health expert and best-selling author of The Age-Proof Brain: New Strategies to Improve Memory, Protect Immunity & Fight Off Dementia, an easy-to-follow guide to cutting-edge medical research that will enable people to keep their brains in tip-top shape for the long haul. He earned his Ph.D. in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA. He has researched topics including cancer biology and neuroscience, and his work has been published in multiple scientific journals. Dr. Milstein has been quoted breaking down and analyzing the latest research in media outlets including USA Today, New York Post, and Oprah Daily. Dr. Milstein has also been featured on television, explaining the latest scientific breakthroughs that improve our life. Dr. Milstein's new book "The Age-Proof Brain" has been nominated for "The Next Big Idea Award" for best non-fiction work and has been a #1 best seller on Amazon in several categories, including, Aging, Longevity, and Neuroscience. Learn more https://drmarcmilstein.com Follow Dr Marc Milstein on social media. Facebook: https://www.facebook.com/drmarcmilstein Instagram: @drmarcmilstein YouTube: https://youtube.com/@DrMarcMilstein   Learn more about Sense of Soul Podcast: https://www.senseofsoulpodcast.com Check out the NEW affiliate deals! https://www.mysenseofsoul.com/sense-of-soul-affiliates-page Check out the Ethereal Network! https://www.mysenseofsoul.com/ethereal-network      

Episode 82 of the Fit Mother Project Podcast is all about brain health and how to improve memory, protect your immunity, and fight off dementia.In this episode, you'll meet Dr. Marc Milstein, who earned a Ph.D. in Biological Chemistry and a Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA, has researched cancer biology and neuroscience, and has been published in multiple scientific journals. You've probably heard a lot lately about fixing gut health to promote longevity, but many people overlook their real superpower: brain health. According to Dr. Milstein, our power to improve brain function lies in the brain's connection with the rest of the body. This means that various lifestyle factors governed by the brain, such as sleep habits and environmental toxins, tend to have a greater impact on our health than we realize. His book, The Age-Proof Brain covers each of these topics and offers integrative, science-supported strategies to increase memory, fight off depression, improve mood, ignite energy, and even prevent dementia and non-genetic Alzheimer's. Dr. Milstein's mission is to educate and empower everybody to take control of their brain health to maximize longevity and reduce the risk of illness. It's an amazing and informative conversation, and Dr. Milstein makes all this complex stuff easily digestible and understandable so we can all live long, healthy, and happy lives!In this episode, you'll learn about: How brain health affects body health.Why embracing getting older can make aging easier and less painful.Little lifestyle changes that can have major impacts.The differences between Alzheimer's and dementia.The causes of common aging issues and what you can do about them.Tips for optimizing nutrition, exercise, sleep, and more.How to train your brain. And so much more!So, if you want to get the most from your health and fitness efforts, listen to this episode on brain health, take some notes, and check out FM30X! More From Dr. Milstein:Dr. Milstein's WebsiteThe Age-Proof BrainDr. Milstein on YouTubeDr. Milstein on InstagramDr. Milstein on FacebookDr. Milstein on LinkedInWhat is FM30X?FM30X is a simple, sustainable, and specific weight loss program that is designed especially for busy women over 40. With short metabolic training workouts, an easy-to-follow meal plan, and an accountability team that is there for you at every step, FM30X can help you lose 30, 40, or even 50+ lbs — even if you've never picked up a weight in your life. Click here to see

References The Journal of Biological Chemistry 2007.282,11356-11364. BMC Biology 2011. 9:85 Cancer Res . 2011 Jan 15;71(2):293-7. J BiolChem. 2023 Mar; 299(3): 103019. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

Michigan State University Interim President Teresa K. Woodruff elaborates on some of the topics she covers in her May 2023 Spartan Community Letter, which you can read by clicking on the communications tab at president.msu.edu. Could you start by reflecting a bit on commencement? And it was cool to see you with the tiny mic going around Breslin Center talking to some of our grads.“Oh, it was so exciting, and I'd never known that tiny mic was a thing. I got to talk to a lot of students, and the really neat thing was to just see their spirit and their enthusiasm. They were excited for that beautiful graduation day. One of the things I did, Russ, is to ask them about their favorite places on campus, and they ranged from the front of Cowles House to the frog pond south of the tracks. I had a couple of people who told me about the frog pond, which I quite love as well, to places for meditation and places that they had been for their classes. It was a wonderful representation of the students love for this campus and this place.”Placemaking is the theme in this month's community letter. How do you define placemaking?“I'm reading William Beal's book on the founding of MSU, and it really is about place and about that place where people could come and learn. This is a place that remains a natural wonder, and we really want to protect the learning, living environment that is the campus. People gain wholeness and in fact in this last semester, of course, healing out of this campus and our campus places. So, the key for us is to really think about those spaces and places and how the new buildings are situated within that larger ethos of a place that is restorative but continues to evolve, and that's what our campus is doing right now. It has the ability to accommodate the new evolution of the way in which we're thinking and learning and doing while really holding fast and true to that beauty and that living, learning environment where we gather when we walk between those places and spaces.”Talk about the freestanding multicultural center that we touched on last month, and what are some of the other facilities on the horizon?“The groundbreaking for that multicultural center was so exciting with standing room only and a lot of folks pitching in to throw that first scoop full of sand to get that process going. And boy, they're going fast over there. In addition, we have the dairy and greenhouses. Those are really teaching and learning facilities that we must have to enable the very best teaching within agriculture, which is our founding and necessary for the state of Michigan. We also are working on our digital innovation center, or EDIC, and this is a place where we'll rebuild what it means to do engineering and digital innovation, scholarship and learning, and bring six colleges together. It's inverting the model of having individual colleges. We're bringing colleges together in this new model.“Our new greenhouses are housing National Academy of Science members working on the scientific discoveries that could really sustain us and sustain this population into the future. We have the Student Recreation and Wellness Center that's going to replace the IM West facility, and folks are really excited about that on this campus.”MSU's annual research and development expenditures grew to almost $760 million in fiscal year 2022. How are some of those funds going towards placemaking?“These new buildings and facilities are going to house new faculty and students, and it's in those facilities that we'll be able to continue our upward trend and upward reach to the heights of research expenditure across not only the Big Ten, but literally in the nation.”Our placemaking extends beyond the East Lansing campus to places like Flint, where you recently visited.“I had the greatest time in Flint, and I really enjoyed that Norm Beauchamp and Aron Sousa were with me when I visited our Charles Stewart Mott Foundation work that's happening there with Mona Hanna-Attisha. We are building a new community partners and research facility there that's really exciting. I met some of the kids who are in that Flint downtown area and they are really excited about Michigan State University. I think I admitted a couple of six-year-olds or maybe even one that's about four years old. So, just full disclosure, Russ, we've got some Flint kids that are coming to MSU in 2042, and I'm already excited to welcome them.”We have the very first philanthropically named department in MSU's history with the Charles Stewart Mott Foundation Department of Public Health.“Public health is so critical as we saw through the COVID context and will continue to have an important way of enlivening the research we do. And particularly in Flint, we're really thoughtful about public health not just being about what MSU researchers think we ought to do and then go do. This is a completely different model where during my visit we had all our community partners who are active participants in the work, folks who then say, ‘Well, this is what we need to know.' In many ways, what we're doing in Flint in health is what we've done in Extension in agriculture. We've really asked for and then developed the partnership that enables the best kind of thinking and therefore the best kind of work, and it's that positive productive cycle that is so exciting in Flint and across all of Michigan.”You also recently had some opportunities to recognize and celebrate the achievements of our amazing staff and faculty.“The key for me is that Michigan State has been celebrating its employees for nearly half a century. This is not a new one off. This is a place that really values every single individual who is part of this whole ecosystem, and I don't think there's anyone who thinks they themselves are above and beyond each other. Whatever part we play within this orchestra that is Michigan State University, we play our parts as well as we can. And in the end, it's a beautiful symphony.”Ensuring the safety of university community members is another vital element of MSU's placemaking for wellbeing. You were recently pleased to welcome a new vice president for civil rights and Title IX education and compliance, Laura Rugless. Tell us about Laura and her important role.“Laura comes from Cornell. She's a veteran and brings an incredible sense of the ways in which we need to focus on prevention and the ways we respond to actual discrimination and sexual violence and misconduct. The folks that I talked with think of her as an ethical people-driven leader. I shared with her this morning that on my computer is a little yellow sticky that says, ‘Today is my favorite day.' I offered to her that every day at MSU is my favorite day, no matter what comes. And I offered that hopefulness and that positivity to her. She embraces MSU, and I'm excited for what her leadership will bring to campus.”You have a bit of a travel advisory for Spartans and others visiting camping this summer.“We've got some traffic detours. As you traverse the campus, you'll have to make some detours, but it's really wonderful. I really like the terrestrial cranes. There are a lot of cranes that are building some of our new buildings, but you'll also see cranes going overhead as we did over graduation; they were headed north. Cranes in the air and cranes on the land really represent the natural and physical beauty of this campus. I invite people to come in this summer. Come to Summer Circle Theatre. Come to just walk in the Beal Garden. Come to see the frogs in the frog pond on the south side of the tracks. There are just so many great places to be and to be present within this great and storied institution.”Results of research you and your husband Tom O'Halloran worked on were recently reported in the Journal of Biological Chemistry. The research looked at the role of zinc in follicle development and how scientists use X-ray beams to determine the role of zinc in development of ovarian follicles. “It represents some profound biology. Before Tom and I collaborated - he was an inorganic chemist, and I'm a reproductive scientist - we collaborated on an area no one had ever thought to look at. We found that the egg, just before fertilization, takes up 20 billion zinc atoms. If it doesn't take up that amount of zinc atoms over a 12-hour period of time, it can't progress to fertilization and then onto an embryo. At the time of fertilization, the zinc is exported from the egg in this big explosion we call the zinc spark. “That zinc spark means that the subordinate sperm cannot actually then come in and have what's called polyspermy. Nobody knew any of this before that work. Tom and I with my last graduate student, Alison Tange, did some work to look at the very earliest stages of follicle development. We used one of the most sophisticated microscopes in the world at Argonne National Labs that Tom actually helped build in order to really look at the zinc and all the other metals in these early follicles. It really was the perfect bridging of new technology and this biology. Again, nobody would've looked for these signatures of life except for that interaction, and it really is just some of the most exciting discoveries that basically happens to all of us at the first moment of conception. I'm just really excited that it has been published.”What are your final thoughts as we really dive into the summer.“I'm excited for everyone to come back to this great campus. The Red Cedar is beautiful, and the trees are in full bloom. During graduation, I think every tree on campus was in peak. MSU is a wonderful place to live and work. I think back on our history of 168 years and know that we are preserving our storied historical campus, but continuing to evolve with what we need to ensure the next generation of students has that great experience that so many have had in the past.”Listen to “MSU Today with Russ White” on the radio and through Spotify, Apple Podcasts, and wherever you get your shows.

This episode covers:An interview with Dr. Marc Milstein. Dr. Marc Milstein is an internationally recognized speaker on optimizing brain health, lowering the risk of dementia, and boosting happiness and productivity. Dr. Milstein earned both his Ph.D. in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA. He has conducted research on topics including genetics, cancer biology, neuroscience, and infectious disease, and his work has been published in multiple scientific journals. In this episode, we discuss why a clean brain is a youthful brain, foods that can help reduce inflammation in the gut, tips for depression and mood improvement, how too much stress affects the brain and so much more.Links I mentioned during this episode:The Age Proof Brain (Dr. Milstein's book): https://amzn.to/3MIGOpuDr. Milstein's website: https://drmarcmilstein.com/Dr. Milstein's Instagram: https://www.instagram.com/drmarcmilstein/Lyons' Share Instagram: www.instagram.com/thelyonsshareJoin Megan's newsletter: www.thelyonsshare.org/newsletterHow to take action after listening to this episode:Go for a 30-minute walk. If a walk doesn't work for you, choose one of the other tips Dr. Milstein shared. There's something for everyone in this episode :) 

Dr. Marc Milstein earned his Ph.D. in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA. He has researched topics including cancer biology and neuroscience, and his work has been published in multiple scientific journals. Dr. Milstein has been quoted breaking down and analyzing the latest research in media outlets including USA Today, New York Post, and Oprah Daily. Dr. Milstein has also been featured on television, explaining the latest scientific breakthroughs that improve our life. Dr. Milstein's new book "The Age-Proof Brain" has been nominated for "The Next Big Idea Award" for best non-fiction work and has been a #1 best seller on Amazon in several categories, including, Aging, Longevity, and Neuroscience.

The brain plays an integral role in the overall welfare of our bodies. So what can we do to optimize our brain health to boost happiness, lower the risk of dementia, maximize productivity, and more? Dr. Marc Milstein joins the podcast today to share his thoughts on this fascinating topic… As an internationally recognized speaker and expert in brain health, Dr. Milstein has made it his goal to educate people around the world. With a Ph.D. in Biological Chemistry from UCLA, Dr. Milstein has conducted research on genetics, cancer biology, neuroscience, and infectious disease – which he draws from to help his audience live healthier, more productive lives. In this episode, we discuss: What drives Dr. Milstein's interest in brain science.  How sleep and brain function are interconnected.  How you can lower your risk of memory loss.  Critical elements for brain health. Want to find out more about Dr. Milstein and his work? Click here now! Episode also available on Apple Podcasts: https://apple.co/38oMlMr

Join us on Wednesday, April 26 @ 6pm EST for an exciting conversation with Scientist, Researcher, International Speaker and Author, Dr. Marc Milstein to discuss his new book The Age-Proof Brain, which has been nominated for "The Next Big Idea Award" for best non-fiction work and has been a #1 best seller on Amazon in several categories, including, Aging, Longevity, and Neuroscience. Dr. Milstein specializes in taking the leading scientific research on health and happiness and presents it in a way that entertains, educates, and empowers his audience to live better. His presentations provide science-based solutions to keep the brain healthy, lower the risk of dementia, boost productivity and maximize longevity. He earned both his Ph.D. in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA. Dr. Milstein has researched topics including cancer biology and neuroscience, and his work has been published in multiple scientific journals. He has been quoted breaking down and analyzing the latest research in popular press such as USA Today, New York Post, and Oprah Daily. Dr. Milstein has also been featured on television, explaining the latest scientific breakthroughs that improve our lives.

In this episode of the "The Gut Health Gurus" podcast, host Kriben Govender interviews Professor Tom Brenna, a renowned expert in the field of nutrition. The conversation delves into the science behind gut health and its relationship to nutrition, with a particular focus on the benefits of consuming omega-3 fatty acids and branched fats. Prof. Brenna provides valuable insights into the complexities of gut health, including how gut microbes influence brain function, and how nutrition can improve gut health and overall wellbeing. He also highlights the benefits of consuming omega-3 fatty acids for cognitive function and the heart. Additionally, the discussion touches on the importance of seafood in a healthy diet and the role of supplementation when needed. Overall, the episode provides a fascinating and informative look at the connection between gut health and nutrition, and how individuals can take control of their health by making simple dietary changes. Bio: Professor Tom Brenna is a renowned scientist and researcher in the field of nutritional sciences. With a Ph.D. in Biological Chemistry from the University of Michigan, Professor Brenna has published over 120 research articles in scientific journals, many of which have been cited extensively. He has also received numerous grants and awards for his research, including the prestigious National Institutes of Health MERIT award. In addition to his academic pursuits, Professor Brenna is also the co-founder and Chief Scientific Officer of VERNX, a company that develops and produces nutritional supplements for optimal health. His research on omega-3 fatty acids and their impact on brain and cardiovascular health has contributed greatly to the field of nutrition and has led to important insights into the role of diet in preventing chronic diseases. Key Topics Discussed: 00:00 - Start 00:30 Introduction to the podcast and guest speaker, Professor Tom Brenna, a leading gastroenterologist 02:12 Omega 3 Fatty Acids 05:50 Omega 3 : Types and Sources 10:30 Omega 3 Shelf life and efficacy 14:46 Omega 3 Dose Levels for Various Conditions 18:00 Omega 3: Food Sources 21:51 What are Branched Fats and how was it discovered? 33:21 Possible Health Benefits of Branched Fats 39:00 How do Branched Fats impact the Microbiome? 44:44 What is Vernx Peribiotic? 47:98 Vernx Peribiotic Spore based Probiotic 50:00 Who is Vernx suitable for? 51:30 What is the effective dose for Vernx? 53:00 Does Vernx strains colonise the gut? 54.23 Is Vernx suitable for Vegans and Vegetarians? 55.00 What gut health issues could Vernx help with? 58.00 Does Vernx exhibit an initial Herxeimer reaction 59.28 Omega 3: Gut Health Benefits 01.02.38 Tom's top Gut Health Tips Brought to you by: Nourishme Organics your online shop for all things Gut Health, including Vernx Peribiotic 10% off using code : happygut https://www.nourishmeorganics.com.au/ Connect with Professor Tom Brenna https://vernx.com/ Connect with Kriben Govender Facebook- https://www.facebook.com/guthealthgurus Instagram- https://www.instagram.com/guthealthgurus Youtube- https://www.youtube.com/c/guthealthgurus?sub_confirmation=1 Tik Tok: https://www.tiktok.com/@guthealthgurus?lang=en Gut Health Gurus Facebook Group: https://www.facebook.com/groups/nourishmeorganics/ Deuterium Depletion Support Group: https://www.facebook.com/groups/mitowellness/ Download links               If you enjoyed this episode and would like to show your support:   1) Please subscribe on Apple Podcasts, give us 5 stars and leave a positive review     Instructions:   - Click this link  https://itunes.apple.com/au/podcast/gut-health-gurus-podcast/id1433882512?mt=2   - Click "View in Itunes" button on the left-hand side - This will open the Itunes app - Click the "Subscribe" button - Click on "Ratings and Reviews" tab - Click on "Write a Review" button   Non-Itunes users can leave a Google Review here: https://goo.gl/9aNP0V     2) Subscribe, like and leave a positive comment on Youtube   https://www.youtube.com/channel/UCq5KxLvGIY4r6SqNaAphEUw?sub_confirmation=1   3) Share your favourite episode on Facebook, Instagram, and Stories 4) Let your friends and family know about this Podcast by email, text, messenger etc   Thank you so much for your support. It means the world to us.                          

Sabemos que a vida, depois de surgir, foi capaz de proliferar e diversificar até que preenchesse todos os nichos do planeta. Mas, uma questão permanece - como a vida surgiu da matéria inorgânica. Separe meia horinha do seu dia e descubra com a Dra. Mila Massuda (@milamassuda) do BlaBlaLogia (@blablalogia) o que a ciência sabe, até o momento, sobre o surgimento da vida na Terra. Apresentação: Mila Massuda (@milamassuda) Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia) Edição: @Matheus_Heredia (@mewmediaLAB) Produção Prof. Vítor Soares (@profvitorsoares) e BláBláLogia (@blablalogia) REFERÊNCIAS: GOMES, Edward; SHORTER, James. The molecular language of membraneless organelles. Journal of Biological Chemistry, v. 294, n. 18, p. 7115-7127, 2019. https://doi.org/10.1074/jbc.TM118.001192 GÖZEN, Irep et al. Protocells: Milestones and recent advances. Small, v. 18, n. 18, p. 2106624, 2022. https://doi.org/10.1002/smll.202106624 JORDAN, Sean F. et al. Spontaneous assembly of redox-active iron-sulfur clusters at low concentrations of cysteine. Nature communications, v. 12, n. 1, p. 5925, 2021. https://doi.org/10.1038/s41467-021-26158-2 KITADAI, Norio; MARUYAMA, Shigenori. Origins of building blocks of life: A review. Geoscience Frontiers, v. 9, n. 4, p. 1117-1153, 2018. https://doi.org/10.1016/j.gsf.2017.07.007 MENOR SALVÁN, Cesar et al. Prebiotic Origin of Pre‐RNA Building Blocks in a Urea “Warm Little Pond” Scenario. ChemBioChem, v. 21, n. 24, p. 3504-3510, 2020. https://doi.org/10.1002/cbic.202000510 MUCHOWSKA, Kamila B.; MORAN, Joseph. Peptide synthesis at the origin of life. Science, v. 370, n. 6518, p. 767-768, 2020. https://www.science.org/doi/10.1126/science.abf1698 OBA, Yasuhiro et al. Identifying the wide diversity of extraterrestrial purine and pyrimidine nucleobases in carbonaceous meteorites. Nature communications, v. 13, n. 1, p. 2008, 2022. https://doi.org/10.1038/s41467-022-29612-x PAPINEAU, Dominic et al. Metabolically diverse primordial microbial communities in Earth's oldest seafloor-hydrothermal jasper. Science Advances, v. 8, n. 15, p. eabm2296, 2022. https://www.science.org/doi/full/10.1126/sciadv.abm2296 PODOLSKY, Kira A.; DEVARAJ, Neal K. Synthesis of lipid membranes for artificial cells. Nature Reviews Chemistry, v. 5, n. 10, p. 676-694, 2021. https://doi.org/10.1038/s41570-021-00303-3 SASSELOV, Dimitar D.; GROTZINGER, John P.; SUTHERLAND, John D. The origin of life as a planetary phenomenon. Science Advances, v. 6, n. 6, p. eaax3419, 2020. https://www.science.org/doi/10.1126/sciadv.aax3419 STOLAR, Tomislav et al. Mechanochemical prebiotic peptide bond formation. Angewandte Chemie International Edition, v. 60, n. 23, p. 12727-12731, 2021. doi: 10.26434/chemrxiv.13187852.v SZOSTAK, Jack W. The narrow road to the deep past: in search of the chemistry of the origin of life. Angewandte Chemie International Edition, v. 56, n. 37, p. 11037-11043, 2017. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201704048 ZHU, Ting F.; SZOSTAK, Jack W. Coupled growth and division of model protocell membranes. Journal of the American Chemical Society, v. 131, n. 15, p. 5705-5713, 2009. https://doi.org/10.1021/ja900919c

Dr. Barry Byrne is the Earl and Christy Powell University Chair in Genetics, Associate Chair of Pediatrics, Director of the Powell Gene Therapy Center, and Professor of Pediatrics and Molecular Genetics and Microbiology at the University of Florida. He conducts research on neuromuscular diseases which may cause problems such as muscle weakness, uncoordinated movements, difficulty speaking, and heart problems. In addition, Barry is a practicing physician who treats patients with these diseases. When he isn't working in the lab or treating patients, Barry enjoys spending time with his family. He also likes to get outdoors to play sports, cycle, or go hiking. Barry received his B.S. in Chemistry from Denison University and his M.D. and Ph.D in Microbiology and Immunology from the University of Illinois. He completed his Pediatrics residency, cardiology fellowship training, and post-doctoral training in Biological Chemistry at Johns Hopkins University Hospital. Barry started his career as a faculty member at Johns Hopkins, and he joined the faculty at the University of Florida in 1997. Barry's excellence in research has been recognized throughout his career through his receipt of various awards including the Faculty Research Prize in Clinical Research and the Research Professor Award from the University of Florida, as well as the Clinician Scientist Award from Johns Hopkins University. In this interview, Barry shares more about his research and his journey through life and science.

References J Cancer Res Clin Oncol. 2018; 144(6): 1065–1077 Nature Reviews Drug Discovery. Sep2014, Vol. 13 Issue 9, p673-691 Anal Cell Pathol (Amst). 2018; 2018: 787.1814 The Journal of Biological Chemistry 16/2/2018 293: 2422-2437. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

#5 — Mike Cianfrocco is Research Assistant Professor at the University of Michigan Life Sciences Institute and Assistant Professor in the Department of Biological Chemistry at the University of Michigan Medical School. In this episode of Cryo-Talk, Mike joins Eva Amsen to talk about the tools he is developing for cryoEM users, such as COSMIC2. He also chats about his love of gardening and fermented foods. Tune in now to hear more!

References Circulation. 2020 Dec 15;142(24):2356-2370. Journal of Biological Chemistry 2016. 291, 23756-23768. Nature Reviews Drug Discovery 2014, Vol. 13 Issue 9, p673-691 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

References Mechanisms of Ageing and Development 2016. 156: 25-33 The Journal of Biological Chemistry 2018. 293: 2422-2437 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

references Am J Physiol Regul Integr Comp Physiol2018. 314: R909–R915. Obesity (Silver Spring). 2008 Jun; 16(6): 1284–1288 Front. Immunol., 26 April 2019 Sec. NK and Innate Lymphoid Cell Biology Journal of Biological Chemistry 2018. 293: 2422-2437 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

Janet Smith, a professor at the University of Michigan Medical School, associate director of the UM Life Sciences Institute and scientific director of the GM/CA beamlines at the Argonne synchrotron, won the 2022 Mildred Cohn Award in Biological Chemistry, which honors scientists at all stages of their careers who have made substantial advances in understanding biological chemistry using innovative physical approaches. She presented her award lecture, "Flavivirus NS1: Structure and function of an enigmatic virulence factor," on Monday, April 4, at the 2022 ASBMB Annual Meeting, held in conjunction with Experimental Biology in Philadelphia. Learn more about her work: https://www.asbmb.org/asbmb-today/people/121721/smith-unravels-secrets-of-nature-s-catalysts.

PARKINSON'S! The term alone is enough to scare a lot of old people out there. It is something that affects lots of people and a lot of men every year.   Today we're joined by Jack Jacobs, PhD, President and Chief Science Officer Zhittya Genesis Medicine, Inc. Las Vegas. And we talk about the work they've been doing to treat Parkinson's with their FGF 1 drug.   Jacob educates us about Parkinson's on what it is, how it affects our body and what they've been doing to treat it.   He also tells us about the tests they've been doing and fortunately, they've been seeing positive results there. All this and a lot more in today's interview. Let's jump right in.   Go to www.thestandard.academy/getmagazine to become one of the first to get my digital magazine for free that'll help you create a kick-ass life.   Dr. Jack Jacobs President and Chief Science Officer Zhittya Genesis Medicine, Inc. Las Vegas, NV Dr. Jacobs received his Ph.D. in Molecular Biology from the Washington University School of Medicine, St. Louis where he worked in the lab of Ralph Bradshaw, PhD which was the first lab to isolate and characterize the growth factor, FGF-1. After graduating, he worked at Merck & Co. where he started the Department of Biological Chemistry and was part of the scientific leadership team at Merck. Later, he joined Daniel Montano at CardioVascular BioTherapeutics as their Chief Scientific Officer where he oversaw FDA-authorized clinical trials in which human FGF-1 was tested in a number of medical indications, including coronary artery disease and diabetic foot ulcers. He also supervised all manufacturing activities of FGF-1 for use in the clinical studies. With Zhittya Genesis Medicine, Dr. Jacobs is continuing his efforts on the clinical development of human FGF-1 for a number of medical indications, including neurodegenerative diseases such as Parkinson's disease and ALS (motor neuron disease)   What is Parkinson's Disease Parkinson's is a progressive, neurodegenerative disorder. In other words, Parkinson's is a lifelong condition that affects the brain and symptoms will get worse over time. Parkinson's happens when cells in the brain that produce dopamine stop working or die. Dopamine is a neurotransmitter, which is a chemical that sends messages between nerve cells or between nerve cells and muscle cells to help the body function. Dopamine plays many roles in the body and affects both physical and mental function.   The cardinal symptoms of Parkinson's are resting tremor, rigidity, slowness of movement (also called bradykinesia) and feeling unsteady and having difficulties with balance (also called postural instability). Because these symptoms are related to movement they are called "motor symptoms" and Parkinson's is classified as a "movement disorder."   However, we now know that Parkinson's also causes "non-motor symptoms." These symptoms include constipation and other gastrointestinal issues, urinary problems, mood changes, sleep disturbances, memory and thinking (cognitive) deficits, sexual problems, excessive sweating, vision problems, and loss of smell or taste. Non-motor symptoms may appear many years before the motor symptoms that eventually lead to a diagnosis.   A bit about me (Dr. Orest Komarnyckyj): Dr. Orest Komarnyckyj enjoyed a prestigious career as a periodontal regenerative surgeon moving to a new passion in June 2018. He retired after a 33-year career to pursue new passions. At 69 Dr. Orest has taken on a new role as an Interviewer, Podcaster and government-certified Old Guy. He streams from his new home in Las Vegas, NV. He lives with his wife of 29 years, Oksana. His status as an empty-nesters with two out of college-employed children has left him with time and energy to share decades of successes, failures, and wisdom.   Timestamp: 00:00 - Precap 00:23 - Intro 01:33 - Guest introduction 03:39 - What's the most important thing you've done today? 04:30 - What do you do at workout? Weights, cardiovascular, or anything else? 05:21 - What causes Parkinsons 07:47 - Dopamine 08:20 - Because of the dopamine decrease, is there depression that's associated with Parkinsons? 08:48 - Why is blood supply important 12:50 - Why exercise is important for old people and people with Parkinson's 14:31 - Do you have a program to keep on course with the exercise program? 15:21 - When you have this increased blood flow into the brain with FGF1, what actually happens? 17:22 - Commercial 17:51 - Commercial ends 18:52 - How long do you talk about seeing some of the aversal of some of the symptoms of Parkinson's and the administration of FGF1? 24:40 - Is FGF 1 available for human use? 27:00 - What other wound healing products does Zhitty Wund Healing BioPharmaceuticals produce and which are available to the public now? 29:50 - Closing thoughts 31:04 - Outro

With so many new markets coming online in the next few years, there are more people than ever before looking for help with permitting, licensing, and everything else that comes with launching a business in a highly regulated industry. When they need that help, they turn to people like today's guest, Dr. Sherry Boodram. She's the CEO and co-founder of CannDelta–a regulatory and scientific consulting company that helps clients navigate both the cannabis and psychedelic industries. Dr. Boodram and her team provide regulatory compliance advice to operate in the legal Canadian markets, and they also provide support to international jurisdictions, including the U.S.  Before launching CannDelta, she was actually a part of the Canadian federal government, serving as Health Canada's Medical Cannabis and Controlled Substances Programs' Senior Regulatory Compliance and Enforcement Officer. She holds a Ph.D in Chemistry, an honorary B.S. in Biological Chemistry, and certificates in Cannabis Law and Regulation as well as Pharmaceutical Regulatory Affairs and Quality Operations. In this conversation, Sherry walks us through the hoops and hurdles facing people looking to break into the cannabis and psychedelics industries, the mistakes so many people make while trying to ensure that they're operating legally, and the key differences between the established Canadian and emerging American markets.  KEY TAKEAWAYS The most common mistakes that people make when trying to get cannabis licenses. Why Shelly transitioned out of government to launch CannDelta–and what she's focused on now. The unique benefits of working with someone who knows Canada's industry so well for anyone planning a launch in a state like New York or New Jersey. Why medical approvals for psilocybin in a number of states are more likely to happen now than ever before. Why social equity has to be such a big part of the American cannabis story–and how Canada failed to integrate First Nations peoples into its legalization.  Show Notes For complete show notes, including transcripts, takeaways, and links to all the resources mentioned, visit SoHoExp.com/55 To learn more about the podcast and get access to all episodes, visit: SoHoExp.com/GreenRepeal

Today's episode will take a deep dive into the science of cancer, asking the hard questions and discussing how regulation may lead to a cure.  Our guest. Dr. Steve Worland, has a strong background in pharmaceuticals, research and molecular biology that led to a powerful discussion with Bob and Shelly. Show Notes Watch episode here Dr. Steve Worland has served as President and Chief Executive Officer of eFFECTOR Therapeutics and as a member of its Board of Directors since its inception in May 2012.  Previously, Dr. Worland served as Chief Executive Officer of Anadys Pharmaceuticals, Inc., a biopharmaceutical company, from August 2007 until its acquisition by Roche Holding AG in 2011.  Prior to his appointment as Chief Executive Officer of Anadys Pharmaceuticals, Dr. Worland served as its Chief Scientific Officer and President, Pharmaceuticals. Prior to Anadys Pharmaceuticals, Inc., Dr. Worland was Vice President and Head of Antiviral Research at Pfizer Inc. and Vice President at WarnerLambert Co., where he was responsible for worldwide anti-infectives strategy.  Dr. Worland has served on the Board of Directors of Tracon Pharmaceuticals, Inc., a biopharmaceutical company, since February 2015.  Dr. Worland was an NIH postdoctoral fellow in molecular biology at Harvard University and completed a Ph.D. in Chemistry at the University of California, Berkeley.  He received his B.S. with Highest Honors in Biological Chemistry from the University of Michigan. eFFECTOR Therapeutics Selective Translation Regulation Inhibitors Pipeline of Selective Translation Regulation Inhibitors Patients and Clinical Trials - eFFECTIVE Therapeutics Investors - eFFECTOR Therapeutics   Battling Bots League (Be Greater Than Average and Electric Playhouse partnership) Robot Rumble (in partnership with Cottonwood Mall) Be Greater Than Average Gift of Learning Be Greater Than Average Courses Be Greater Than Average Family Fun! Be Greater Than Average A Semester of STEM Activities E-Book   Contact:   Steve Worland, Ph.D., President and Chief Executive Officer eFFECTOR Therapeutics 142 North Cedros Avenue, Suite B Solana Beach, CA 92075 (858) 925-8215 info@effector.com Linkedin eFFECTOR Therapeutics, Inc. (Linkedin) eFFECTOR_Rx (Twitter)  

Dr. Aparna Bhaduri, Assistant Professor of Biological Chemistry at UCLA, talks about her research on human brain development and glioblastoma.  ----------------------------------- Thanks to the partners: Newsly: https://newsly.mepromo code: EARLYMORNING. Anchor https://anchor.fm Libysn https://libsyn.compromo code: DG Hardsnake Energy https://www.instagram.com/hardsnakenrgy spikeview https://www.spikeview.comhttps://www.instagram.com/spikeview ------------------------------------------------------------------------  Listen on:  Podcast website: https://anchor.fm/diamondgoat  Spotify: https://open.spotify.com/show/0EuhA6WyuerHtVAqcFrFeO  Google Podcast: https://www.google.com/podcasts?feed=aHR0cHM6Ly9hbmNob3IuZm0vcy80NzE4MzM5MC9wb2RjYXN0L3Jzcw==  RadioPublic: https://radiopublic.com/dg-earlymorning-show-WoML4r  Breaker: https://www.breaker.audio/dg-early-morning-show  Podcast YT channel clips: https://www.youtube.com/channel/UCPZdwPiE-Rb7yv0qQ_7Nqpw  Reason: https://reason.fm/podcast/dg-earlymorning-show  Apple Podcast: https://podcasts.apple.com/us/podcast/dg-early-morning-show/id1575451533  Amazon Music: https://music.amazon.com/podcasts/f050b86c-1dad-4bc3-b12f-6aa5fa62438c  --------------------------------------  Check out my other stuff:  Instagram: @itzdiamondgoat  Twitter: https://twitter.com/lildiamondgoat  Main YT channel: youtube.com/diamondgoat  Tiktok: @lildiamondgoat  Soundcloud: @Lil Diamondgoat  Spotify: @Lil Diamondgoat  Merch store: https://diamondgoat.creator-spring.com --- Support this podcast: https://podcasters.spotify.com/pod/show/diamondgoat/support

References Journal of Biological Chemistry.2013. 288 Issue 52 Pages 37355-37364. Prostaglandins & Other Lipid Mediators. 2022(April) . Volume 159, 106621 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

Lovisa Afzelius is an origination partner at Flagship Pioneering and the former SVP of Strategy & Operations at Flagship-founded Cogen Immune Medicines, now known as Repertoire Immune Medicines. A computational scientist by training, she has two decades of leadership experience and a passion for data-driven drug discovery, from early inception to clinical development across multiple therapeutic areas. Previously, Lovisa built and led Pfizer's systems immunology function and served as executive director of clinical programs. In this role, she launched several Phase II studies across autoimmune indications and as a member of the Inflammation & Immunology Research Unit leadership team, Lovisa co-managed the portfolio from early target discovery to Phase II clinical trials across all immunological assets. In addition, she served on Pfizer's Worldwide R&D Data Strategy Committee. In 2017, Lovisa co-founded Elsa.science, a digital health company in the rheumatoid arthritis space where she serves as chairman of the board. She also serves on the board of the Swedish New England Chamber of Commerce. Before moving to the US in 2013, Lovisa was CEO of BioChromix Pharma. Lovisa began her career at AstraZeneca as Project Director, Global In Vitro Metabolism Leader and Computational Chemist across cardiovascular, metabolic, and neurodegenerative diseases. Lovisa has received numerous accolades for her work: she was included in the top 100 ​“most influential persons under age 40 in Sweden” by Affärsvärlden, and ​“scientist of tomorrow” at the European Federation of Pharmaceutical Industries and Associations' 30th anniversary. Lovisa received the Rosenön Award for best thesis of the year within the field of pharmacodynamics/​pharmacokinetics in Sweden. Lovisa holds a Ph.D. in computational chemistry from Uppsala University, a Master of Science in integrative pharmacology from Gothenburg University as well as an M.B.A. from the MIT Sloan School of Management. Theonie is a principal at Flagship Pioneering where she conceives, builds and grows the science, intellectual property and business strategy that form the foundation of Flagship's next breakthrough startups. She co-founded Alltrna and serves as its chief innovation officer. Prior to joining Flagship, Theonie completed her graduate studies in cell and molecular biology at the Perelman School of Medicine at the University of Pennsylvania. Her research focused on replication fork dynamics in the context of cancer development and therapeutics. Theonie has received several awards and has been granted multiple fellowships for her academic work, including an NIH NRSA Predoctoral Fellowship. During her graduate studies, Theonie held multiple leadership positions on Executive and Curriculum Committees. She also completed a Wharton Business Foundations Specialization and was a mentor at the yearly Larta Institute NIH CAP FeedForward Sessions. Theonie is a Business Advisory Board member of the Harvard Institute for RNA Medicine and a member of the Bioscience & Investor Inclusion Group (BIIG) Diverse Talent Network Group. Theonie's work has resulted in multiple pending patents and publications, including articles in Nature Biotechnology, Molecular Cell and Journal of Biological Chemistry.

I was so excited to host Duane Mancini, the Founder & CEO of Project Med-Tech, primarily because Duane and his team are adding so much value to the industry at large by way of the fantastic content they put out on a regular basis.Duane hosts the Project MedTech podcast where he interviews leading experts in the Medical Device industry on a variety of topics related to major successes, pitfalls, and trends.Recently, Project MedTech has morphed into a full-blown business of resources for Med-Tech startups at any phase the company is working through.For over 10+ years, Duane has held a variety of roles in the Med-Tech industry (Chemist, Sr Technical Advisor, and multiple Business Development roles with companies like NAMSA and LabCor.Duane holds his Bachelors and Masters degrees in Medicinal and Biological Chemistry from the University of Toldeo.Some of the highlights we discussing during this episode:-How Project Medtech support Startups and the resources they can provide-How crucial it is to understand Regulatory, Reimbursement, & Commercialization and how each affects business decisions-The most surprising feedback Duane has received from an Investor's point of view...and so much more!

On this episode of Molecular Moments, Chad Briscoe chats with Dr. Jennifer Zemo, Director, Bioanalytical Operations at BioAgilytix. She’s a great leader, mentor and scientist with a love for helping people and the sciences. They discuss her start as a chemistry major in college, which led to her Ph.D. in Biological Chemistry and eventually to joining BioAgilytix 8 years ago. A large molecule expert, Jennifer shares how she went from pharma to CRO, the importance of customer service and the ability to be creative in assay development. They also discuss how company culture shifted during the COVID pandemic, the first place she would like to visit after things go back to normal and what motivates her. See omnystudio.com/listener for privacy information.

There is so much more to keeping your brain in tip-top-shape and lowering your risk for dementia than crossword puzzles, brain games and Sudoku. Breakthrough research is uncovering the surprising, key actionable steps to boost your brain and keep it working better, longer. Hear the scoop on scientifically valid, actionable tips to optimize your brain health and what is just myth, hype and marketing. Utilize the latest science to empower you to keep your brain young. Dr. Marc Milstein is an internationally recognized speaker on optimizing brain health, lowering risk of dementia and boosting happiness and productivity. Dr. Milstein earned both his Ph.D. in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA.

Featured interview: Analysis on Israel's COVID-19 vaccination success and prospects for herd immunity with the current vaccine rollout pace -이스라엘의 코로나바이러스 집단면역 진행 현황 Guest: Professor Michal Linial, Department of Biological Chemistry, The Hebrew University of Jerusalem

Dr. Clifford Beall is a Research Assistant Professor at the Ohio State University. He received his Bachelor's in Biology from the California Institute of Technology and his PhD in Biological Chemistry from Harvard University. Cliff later received a Masters in Intelligent Systems from the University of Sussex in the United Kingdom. Cliff is here with us today to tell us about his journey through life and science.