Podcasts about Rhabdomyolysis

Limb-girdle muscular dystrophies (LGMDs) encompass a group of genetically heterogeneous skeletal muscle disorders. There has been an explosion of newly identified LGMD subtypes in the past decade, and results from preclinical studies and early-stage clinical trials of genetic therapies are promising for future disease-specific treatments. In this episode, Gordon Smith, MD, FAAN, speaks with Teerin Liewluck, MD, FAAN, FANA, author of the article “Limb-Girdle Muscular Dystrophies” in the Continuum® October 2025 Muscle and Neuromuscular Junction Disorders issue. Dr. Smith is a Continuum® Audio interviewer and a professor and chair of neurology at Kenneth and Dianne Wright Distinguished Chair in Clinical and Translational Research at Virginia Commonwealth University in Richmond, Virginia. Dr. Liewluck is a professor of neurology at the Division of Neuromuscular Medicine and Muscle Pathology Laboratory at Mayo Clinic College of Medicine in Rochester, Minnesota. Additional Resources Read the article: Limb-Girdle Muscular Dystrophies Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @gordonsmithMD Guest: @TLiewluck Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Smith: This is Dr Gordon Smith with Continuum Audio. Today I'm interviewing Dr Teerin Liewluck, a good friend of mine at the Mayo Clinic, about his article on the limb girdle muscular dystrophies. This article appears in the October 2025 Continuum issue on muscle and neuromuscular junction disorders, a topic that is near and dear to my heart. Teerin, welcome to the podcast, and maybe you can introduce yourself to our listeners. Dr Liewluck: Thank you very much, Gordon, and I want to say hi to all the Continuum fans. So, I'm Dr Teerin Liewluck, I'm the professor of neurology at Mayo Clinic in Rochester, Minnesota. So, my practice focus on all aspects of muscle diseases, both acquired and genetic myopathies. Glad to be here. Dr Smith: I just had the great pleasure of seeing you at a seminar in Houston where you talked about this topic. And so, I'm really primed for this conversation, which I'm very excited about. I find this topic a little hard, and I'm hoping I can learn more from you. And I wonder if, as we get started, recognizing many of our listeners are not in practices focused purely on muscle disease, maybe you can provide some context about why this is important for folks doing general neurology or even general neuromuscular medicine? Why do they need to know about this? Dr Liewluck: Yes, certainly. So, I would say limb girdle muscular dystrophy probably the most complex category of subgroup of muscle diseases because, by itself, it includes thirty-four different subtypes, and the number's still expanding. So, each subtype is very rare. But if you group together, it really have significant number of patients, and these patients present with proximal weakness, very high CK, and these are common patients that can show up in the neurology clinic. So, I think it's very important even for general neurologists to pick up what subtle clues that may lead to the diagnosis because if we are able to provide correct diagnosis for the patients, that's very important for patient management. Dr Smith: So, I wonder if maybe we can talk a little bit about the phenotype, Terran. I mean, your article does a great job of going over the great diversity. And you know, I think many of us here, you know, limb girdle muscular dystrophy and we think of limb girdle weakness, but the phenotypic spectrum is bananas, right? Rhabdomyolysis, limb girdle distal myopathy. I mean, when should our listeners suspect LGMD? Dr Liewluck: Yes, I think by the definition to all the LGMD patients will have limb girdle of proximal weakness and very high CK. So, these are common phenotypes among thirty-four different subtypes. But if it did take into details, they have some subtle differences. In the article, what I try to simplify all these different subtypes that we can categorize at least half of them into three main group that each group the underlying defect sharing among those subtypes and also translate into similar muscles and extra muscular manifestations. You will learn that some of the limb girdle muscular dystrophy may present with rhabdomyolysis. And we typically think of this as metabolic myopathies. But if you have a rhabdomyolysis patient, the CK remain elevated even after the acute episode, that's the key that we need to think this could be LGMD. That's for an example. Dr Smith: So, I wonder if maybe we can start there. I was going to go in a different direction, but this is a good transition. It's easy to see the opportunity to get confused between LGMD or, in that case, a metabolic myopathy or other acquired myopathies. And I think particularly adult neurologists are more accustomed to seeing acquired muscle disease. Are there particular clues that, or pearls that adult neurologists seeing patients with muscle disease can use to recognize when they should be thinking about LGMD given the diverse phenotype? Dr Liewluck: Yes. What I always tell the patient is that there are more than a hundred different types of muscle diseases, but we can easily divide into groups: acquired and genetic or hereditary. So, the acquired disease is when you encounter the patients who present with acute or subacute cause of the weakness, relatively rapidly progressive. But on the opposite, if you encounter the patient who present with a much more slowly progressive cause of weakness over several months or years, you may need to think about genetic disease of the muscle with also including limb-girdle muscular dystrophy. The detailed exam to be able to distinguish between each type of muscular dystrophy. For example, if proximal weakness, certainly limb girdle muscular dystrophy. If a patient has facial weakness, scapular winking, so you would think about facial scapular hematoma dystrophy. So, the slowly progressive cause of weakness, proximal pattern of weakness, CK elevation, should be the point when you think about LGMD. Dr Smith: So, I have a question about diagnostic evaluation. I had a meeting with one of my colleagues, Qihua Fan, who's a great peripheral nerve expert, who also does neuromuscular pathology. And we were talking about how the pathology field has changed so much over the last ten years, and we're doing obviously fewer muscle biopsies. Our way of diagnosing them has changed a lot with the evolution of genetic testing. What's your diagnostic approach? Do you go right to genetic testing? Do you do targeted testing based on phenotype? What words of wisdom do you have there? Dr Liewluck: Yes, so, I mean, being a muscle pathologist myself, it is fair to say that the utility of muscle biopsies when you encounter a patient with suspects that limb girdle muscular dystrophy have reduced over the year. For example, we used to have like fifteen, seventeen hundred muscle biopsies a year; now we do only thirteen hundred biopsies a year. Yes, as you pointed out, the first step in my practice if I suspect LGMD is to go with genetic testing. And I would prefer the last gene panel that not only include the LGMD, but also include all other genetic muscle disease as well as the conjunctive myopic syndrome, because the phenotype can be somehow difficult to distinguish in certain patients. Dr Smith: So, do you ever get a muscle biopsy, Teerin? I mean you obviously do; only thirteen hundred. Holy cow, that's a lot. So, let me reframe my question. When do you get a muscle biopsy in these patients? Dr Liewluck: Muscle biopsy still is present in LGMD patients, it's just we don't use it at the first-tier diagnostic test anymore. So, we typically do it in selected cases after the genetic testing in those that came back inconclusive. As you know, you may run into the variant of unknown significance. You may use the muscle biopsy to see, is there any histopathology or abnormal protein Western blot that may further support the heterogenicity of the VUS. So, we still do it, but it typically comes after genetic testing and only in the selected cases that have inconclusive results or negative genetic testing. Dr Smith: I'd like to ask a question regarding serologic testing for autoantibodies. I refer to a really great case in your article. There are several of them, but this is a patient, a FKRP patient, who was originally thought to have dermatomyositis based on a low-titer ME2 antibody. You guys figured out the correct diagnosis. We send a lot of antibody panels out. Wonder if you have any wisdom, pearls, pitfalls, for how to interpret antibody tests in patients with chronic myopathies? We send a lot of them. And that's the sort of population where we need to be thinking about limb-girdle muscular dystrophies. It's a great case for those, which I hope is everyone who read your article in detail. What do you have to say about that? Dr Liewluck: Yes, so myositis antibodies, we already revolutionized a few of muscle diseases. I recall when I finished my fellowship thirteen years ago, so we don't really have much muscle myositis antibodies to check. But now the panel is expanded. But again, the antibodies alone cannot lead to diagnosis. You need to go back to your clinical. You need to make sure the clinical antibodies findings are matched. For example, if the key that- if the myocytes specific antibodies present only at the low positive title, it's more often to be false positive. So, you need to look carefully back in the patient, the group of phenotypes, and when in doubt we need to do muscle biopsies. Now on the opposite end, the other group of the antibody is the one for necrotizing autoimmune myopathy; or, the other name, immune-mediated necrotizing myopathy. This is the new group that we have learned only just recently that some patients may present as a typical presentation. I mean, when even thinking about the whole testing autoimmune myopathy, we think about those that present with some acute rapidly progressive weakness, maybe has history of sudden exposures. But we have some patients that present with very slowly progressive weakness like muscular dystrophies. So now in my practice, if I encounter a patient I suspect LGMD, in addition to doing genetic testing for LGMD, I also test for necrotizing doing with myopathy antibodies at the same time. And we typically get antibody back within what, a week or two, but projected testing would take a few months. Dr Smith: Yeah. And I guess maybe you could talk a little bit about pitfalls and interpretation of genetic tests, right? I think you have another case in your article, and I've certainly seen this, where a patient is misdiagnosed as having a genetic myopathy, LGMD, based on, let's say, just a misinterpretation of the genetic testing, right? So, I think we need to think of it on both sides. And I like the fact that the clinical aspects of diagnosis really are first and foremost most important. But maybe you can talk about wisdom in terms of interpretation of the genetic panel?  Dr Liewluck:Yes. So genetic testing, I think, is a complex issue, particularly for interpretation. And if you're not familiar with this, it's probably best to have your colleagues in genetics that help looking at this together. So, I think the common scenario we encounter is that in those dystrophies that are autosomal recessive, so we expect that the patient needs to have two abnormal copies of the genes to cause the disease. And if patients have only one abnormal copy, they are just a carrier. And commonly we see patients refer to us as much as dystrophy is by having only one abnormal copy. If they are a carrier, they should not have the weakness from that gene abnormality. So, this would be the principle that we really need to adhere. And if you run into those cases, then maybe you need to broaden your differential diagnosis. Dr Smith: I want to go back to the clinical phenomenology, and I've got a admission to make to you, Teerin. And I find it really hard to keep track of these disorders at, you know, thirty-four and climbing a lot of overlap, and it's hard to remember them. And I'm glad that I'm now going to have a Continuum article I can go to and look at the really great tables to sort things out. I'm curious whether you have all these top of mind? Do you have to look at the table too? And how should people who are seeing these patients organize their thoughts about it? I mean, is it important that you memorize all thirty-four plus disorders? How can you group them? What's your overall approach to that? Dr Liewluck: I need to admit that I've not memorize all twenty-four different subtypes, but I think what I triy to do even in my real-life practice is group it all together if you can. For example, I think that the biggest group of these LGMD is what we call alpha-dystroglycanopathies. So, this include already ten different subtypes of recessive LGMD. So alpha-dystroglycan is the core of the dystrophin-associated glycoprotein complex. And it's heavy glycosylated protein. So, the effect in ten different genes can affect the glycosylation or the process of adding sugar chain to this alpha-dystroglycan. And they have similar features in terms of the phenotype. They present with proximal weakness, calf pseudohypertrophy, very high CK, some may have recurrent rhabdomyolysis, and cardiac and rhythmic involvement are very common. This is one major group. Now the second group is the limb-girdle muscular dystrophy due to defective membrane repair, which includes two subtypes is the different and on dopamine five. The common feature in this group is that the weakness can be asymmetric and despite proximal weakness, they can have calf atrophy. On muscle biopsy sometimes you can see a myeloid on the muscle tissues. And the third group is the sarcoglycanopathy, which includes four different subtypes, and the presentation can look like we share. For the rest, sometimes go back to the table. Dr Smith: Thank you for that. And it prompts another question that I always wonder about. Do you have any theories about why such variability in the muscle groups that are involved? I mean, you just brought up dystroglycanopathy, for instance, as something that can cause a very distal predominant myopathy; others do not. Do we at this point now have an understanding given the better genetics that we have on this and work going on in therapeutic development, which I want to get to in a minute, that provides any insight why certain muscle groups are more affected? Dr Liewluck: Very good question, Gordon. And I would say the first question that led me interested in muscle disease---and this happened probably back in 2000 when I just finished medical school---is why, why, why? Why does muscle disease tend to affect proximal muscles? I thought by now, twenty-five years later, we'd have the answer. I don't. I think this, you don't know clearly why muscle diseases, some affect proximal, some affect distal. But the hypothesis is, and probably my personal hypothesis is, that maybe certain proteins may express more in certain muscles and that may affect different phenotypes. But, I mean, dysferlin has very good examples that can confuse us because some patients present with distal weakness, some patients present with proximal weakness, that's by the same gene defect. And in this patient, when we look at the MRI in detail, actually the patterns of fatty replacements in muscle are the same. Even patient who present clinically as a proximal or distal weakness, the imaging studies show the same finding. Bottom line, we don't know. Dr Smith: Yeah, who knew it could be so complex? Teerin, you brought up a really great point that I wanted to ask about, which is muscle MRI scan, right? We're now seeing studies that are doing very broad MR imaging. Do you use some muscle MRI very frequently in your clinical evaluation of these patients? And if so, how? Dr Liewluck: Maybe I don't use it as much as I could, but the most common scenario I use in this setting is when I have the genetic testing come back with the VUS. So, we look at each VUS, each gene in detail. And if anything is suspicious, what I do typically go back to the literature to see if that gene defect in particular has any common pattern of muscle involvement on the MRI. And if there is, I use MRI as one of the two to try to see if I can escalate the pathogenicity of that VUS. Dr Smith: And a VUS is a “Variant of Unknown Significance,” for our listeners. I'm proud that I remember that as a geneticist. These are exciting times in neurology in general, but particularly in an inherited muscle disease. And we're seeing a lot of therapeutic development, a lot going on in Duchenne now. What's the latest in terms of disease-modifying therapeutics and gene therapies in LGMD? Dr Liewluck: Yes. So, there are several precritical and early-phase critical trials for gene therapy for the common lymphoma of muscular dystrophies. For example, the sarcoglycanopathies, and they also have some biochemical therapy that arepossible for the LGMD to FKRP. But there are many things that I expect probably will come into the picture broader or later phase of critical tryouts, and hopefully we have something to offer for the patients similar to patients with Duchenne muscular dystrophy. Dr Smith: What haven't we talked about, I mean, holy cow? There's so much in your article. What's one thing we haven't talked about that our listeners need to hear? Dr Liewluck: Good questions. So, I think we covered all, but often we get patients with proximal weakness and high CK, and they all got labeled as having limb-girdlemuscular dystrophy. What I want to stress is that proximal weakness and high CK is a common feature for muscle diseases, so they need to think broad, need to think about all possibilities. Particularly don't want to miss something treatable. Chronic, slowly progressive cause, as I mentioned earlier, we think more about muscle dystrophy, but at the cranial range, we know that rare patients with necrotic autonomyopathy and present with limb good of weakness at a slowly progressive cost. So, make sure you think about these two when suspecting that LGMD patient diabetic testing has come back inconclusive. Dr Smith: Well, that's very helpful. And fortunately, there's several other articles in this issue of Continuum that help people think through this issue more broadly. Teerin, you certainly don't disappoint. I enjoyed listening to you about a month ago, and I enjoyed reading your article a great deal and enjoy talking to you even more. Thank you very much. Dr Liewluck: Thank you very much, Gordon. Dr Smith: Again, today I've been interviewing Dr Teerin Liewluck about his article on limb-girdle muscular dystrophy, which appears in the October 2025 Continuum issue on muscle and neuromuscular junction disorders. Please be sure to check out Continuum Audio episodes for this and other issues. And thanks to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

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Mike DeGeorge is a 27-year-old ultra runner from Albany, NY, who only started running in 2020 and is already competing at an elite level. After discovering David Goggins and using running to turn his life around, Mike built up to 180-mile training weeks, shattered the Brookfield Classic 50K course record, ran 100 miles at a 7:30 pace, and logged 141 miles in 24 hours. In this episode Mike talks about training, discipline, a near-death experience, recovery, and what drives him to chase the dream of joining Team USA. Outside of running, Mike works in a homeless program, has dedicated the past 10 years of his life to homeless services, and is a father to one daughter.Instagram: https://www.instagram.com/mikeedegeorgeChapters00:00 Meet Mike DeGeorge02:30 How David Goggins Sparked a Life Change05:00 Building to 180-Mile Weeks and Training on a Treadmill09:30 Breaking the Brookfield Classic 50K Course Record12:15 Tackling 5,000 Feet of Climb in Worn-Out Road Shoes14:45 Fueling and Strategy — Gels, LMNT, and Ketone IQ18:30 The 100-Mile Treadmill Challenge (12 h 29 m at 7:30 pace!)21:00 Winning 24-Hour Races and Running in the Dark30:00 Training Breakdown — Mileage, Lifting, Recovery & Diet37:00 Balancing Work, Fatherhood & Training 3 Hours a Day43:00 The Dream: Team USA 24-Hour Championship Goal48:00 Near Death with Rhabdomyolysis at 141 Miles53:00 Lessons from Failure & The Fat Ox Redemption Race1:02:00 Music on the Run — Eminem Motivation1:05:00 Coaching, Structured Training & Favorite Shoes1:09:00 Final Thoughts — Inspiration Through RunningThe Co-Movement Gym Podcast is supported by Native Path Supplements and Lombardi Chiropractic.

Maddy presents a case of atraumatic rhabdomyolysis to Youssef, Andrew, and Noah.

Send us a text if you want to be on the Podcast & explain why!The fitness industry has a dark secret that qualified trainers need to address head-on: exercise-induced rhabdomyolysis. This potentially life-threatening condition, once primarily associated with catastrophic events or extreme military training, has become disturbingly common in regular gym settings due to unqualified trainers pushing clients too hard, too fast.This eye-opening episode tackles a real case study of a 38-year-old client who developed rhabdomyolysis after just her second session with a previous trainer. What should have been a routine workout turned into a five-day hospital stay with dangerously elevated creatine kinase levels of 10,000 (normal post-exercise levels might reach 600-700). The culprit? A punishing 90-minute session filled with high-repetition exercises, minimal rest, and culminating in exhaustive rowing - a perfect recipe for disaster.We break down exactly how qualified trainers should approach clients with fitness trauma, beginning with the crucial first workout. You'll discover the specific exercise selection, rep schemes, and rest periods that rebuild trust while still creating an effective session. The detailed programming walkthrough demonstrates how to gradually increase intensity over subsequent sessions while ensuring the client feels safe and successful.What makes this case particularly powerful is the outcome: through proper progression and client-centered training, this traumatized client stayed with the qualified trainer for over three years. The key wasn't just physical programming but psychological understanding - acknowledging fears, educating about exercise physiology, and prioritizing the client relationship over ego-driven "tough" workouts.Whether you're a personal trainer looking to level up your skills or a fitness enthusiast wanting to understand what separates qualified professionals from dangerous ones, this episode delivers actionable insights that could prevent injury and potWant to ask us a question? Email email info@showupfitness.com with the subject line PODCAST QUESTION to get your question answered live on the show! Our Instagram: https://www.instagram.com/showupfitnessinternship/?hl=enTikTok: https://www.tiktok.com/@showupfitnessinternshipWebsite: https://www.showupfitness.com/Become a Personal Trainer Book (Amazon): https://www.amazon.com/How-Become-Personal-Trainer-Successful/dp/B08WS992F8Show Up Fitness Internship & CPT: https://online.showupfitness.com/pages/online-show-up?utm_term=show%20up%20fitnessNASM study guide: ...

This episode delves into the serious condition of rhabdomyolysis, commonly referred to as rhabdo, particularly in the context of endurance sports. The host explains the basics of rhabdo, its causes, and the specific risks associated with ultra-running. Key risk factors such as prolonged exertion, dehydration, and heat stress are discussed, along with the symptoms to watch for, including muscle pain, weakness, and dark urine. The conversation emphasizes the importance of proper training, hydration strategies, and listening to one's body to prevent rhabdo. Treatment options are also briefly covered, highlighting the need for medical intervention in severe cases. The episode concludes with a reminder of the extreme nature of ultra-running and the importance of awareness and preparation.Connect with us:

Gugs Mhlungu speak to Director at Fitpro Institute of Fitness Professionals & Head of Strength & Conditioning at St David Marist Inanda, Derek Archer helps us better understand how Rhabdomyolysis can affect your fitness and on how to prevent overexercising and on how to treat some illnesses due overexercising. See omnystudio.com/listener for privacy information.

Rhabdomyolysis [rhab-doe-my-AL-uh-sis], or rhabdo for short, occurs when muscles damaged during strenuous activity release…

Rhabdomyolysis [rhab-doe-my-AL-uh-sis], or rhabdo for short, occurs when muscles damaged during strenuous activity release…

Rhabdomyolysis [rhab-doe-my-AL-uh-sis], or rhabdo for short, occurs when muscles damaged during strenuous activity release proteins into the bloodstream. As these toxins travel to other organs, they can be deadly. Apart...

Rhabdomyolysis [rhab-doe-my-AL-uh-sis], or rhabdo for short, occurs when muscles damaged during strenuous activity release proteins into the bloodstream. As these toxins travel to other organs, they can be deadly. Apart...

Training must be measured; the right amount of the right kind must be applied at the right time. In this Podcast Emylee and I discuss her scare with Rhabdomyolysis, what it taught her and how she rebuilt her body and her mind from the ground up. The hardest lessons can sometimes be the most educational...Listen, share and reach out if something similar has happened to you and you need advice or help! Join the PAC and learn how to set yourself up for success, one habit at a time.Welcome to the Pac, please make sure you subscribe wherever you are listening to this show and if you loved this show please leave us a 5 star review in the iTunes store. It is the currency of podcasts and it really goes along in helping us grow our show.If you are in Southern California come train with us Echo ParkRedondo BeachIdyllwildPalm SpringsFollow Pharos, Piet and Emylee on Instagram for more fitness related content. Hosted on Acast. See acast.com/privacy for more information.

After a high-intensity workout class left her hospitalized from exercise-induced rhabdomyolysis, Kami's persistent symptoms led to a second opinion and a diagnosis of pectus excavatum—a condition that affects the heart and lungs by compressing the chest cavity. Hear Kami's firsthand account of her journey, including her symptoms of locked "T-Rex arms," swollen muscles, and nausea, and the missteps in her initial medical care. Discover how a cardiologist uncovered the real issue and why advocating for yourself can be the key to better health outcomes. Whether you're an athlete, trainer, or someone who exercises, this episode dives into the lesser-known risks of intense workouts and what the fitness industry often overlooks about rhabdomyolysis. Don't miss this powerful story of resilience, education, and self-advocacy.   Supplement Facts Coffee Mug: https://joecannon.creator-spring.com/listing/supplement-facts-mug   Consultations  https://supplementclarity.com/private-consultations/     Get My Rhabdo Book   Education is the best defense against getting rhabdomyolysis. I've been teaching about rhabdo for over 10 years. If you are in the US, you can order my book directly from me. Order on Amazon    Connect With Me Joe-Cannon.com SupplementClarity.com YouTube   Rhabdo Talk Youtube Channel   About Me   For over 30 years I've been sorting nutrition facts from fiction, busting myths and helping people understand dietary supplements using clinical research as my litmus test.    I have an MS in exercise science and a BS in biology & chemistry. I've written several books, including Rhabdo, the first book about exercise-induced rhabdomyolysis.   Disclaimer   Episodes are for information only. I'm not a medical doctor, and no medical advice is given or implied. ALWAYS consult your physician for the best health advice for you. I participate in the Amazon Associates program, which means if you click on a link to Amazon and make a purchase, I may make a small commission at no extra cost to you.

In this podcast, a study from Ontario revealed that SGLT2 inhibitors, when combined with statins, were associated with a 25% lower risk of rhabdomyolysis compared to DPP4 inhibitors. A phase I trial at Washington University demonstrated promising outcomes for a neoantigen DNA vaccine aimed at preventing recurrence in triple-negative breast cancer (TNBC). Finally, intensive systolic blood pressure control in Chinese patients with type 2 diabetes and elevated cardiovascular risk significantly reduced major cardiovascular events compared to standard care.

In this Debrief episode, I delve into the balance between fitness and mental resilience, exploring the thin line between disciplined commitment and obsession. With insights from icons like David Goggins and Mark Manson, we uncover what drives extreme exercise and how to keep a healthy perspective. Pro surfer Laird Hamilton and free climber Alex Honnold bring fresh views on risk and motivation, helping us assess personal limits. From transitioning between fitness styles to the significance of martial arts etiquette, we discuss injury prevention, respect, and authenticity—offering a guide to achieving both personal and physical growth.--------- EPISODE CHAPTERS ---------(0:00:00) - Fitness and Discipline Conversation(0:08:12) - Physical Training and Injury Prevention(0:17:10) - Rhabdo Risks in Athletic Workouts(0:27:53) - Martial Arts Etiquette and Respect(0:42:21) - Key Elements of Martial Arts Training(0:52:44) - Embracing Authenticity and Overcoming Imposter Syndrome(0:59:41) - Open Invitation for Discussion and SharingSend us a text

Join Joe Adams in this episode of The Relentless Pursuit Podcast as he sits down with David Compton. From navigating multiple life-altering experiences, including devastating divorces and a Rhabdomyolysis diagnosis, to finding peace and passion in ultra-running, David shares his incredible journey. - They discuss the importance of finding balance in life, pushing one's limits safely, understanding the importance of communication in relationships, and the relentless pursuit of personal fulfillment and purpose. Alongside inspiring tales of endurance, listeners will also hear about the significance of having a supportive community and the impact of facing one's vulnerabilities. - Tune in for a raw and inspiring conversation that underscores the power of resilience and the ongoing search for purpose. Don't forget to like, subscribe, and hit the notification bell for more impactful stories.

Strength and performance coaches need to balance pushing athletes to their peak without pushing them into danger. In this episode of “Random Fit,” hosts, and NASM Master Instructors, Wendy Batts, and Ken Miller, explore Rhabdomyolysis—a potentially deadly condition that can result from overexertion. They'll cover policy changes, high-profile collegiate cases, and the early signs of Rhabdo. This discussion is packed with insights for Strength Coaches/Performance Enhancement Specialists and Personal Trainers alike. Learn how to protect your athletes with smarter training, effective recovery, and proper hydration techniques.   If you like what you just consumed, leave us a 5-star review, and share this episode with a friend to help grow our NASM health and wellness community! Introducing NASM One, the membership for trainers and coaches. For just $35/mo., get unlimited access to over 300 continuing education courses, 50% off additional certifications and specializations, EDGE Trainer Pro all-in-one coaching app to grow your business, unlimited exam attempts and select waived fees. Stay on top of your game and ahead of the curve as a fitness professional with NASM One. Click here to learn more. https://bit.ly/4ddsgrm

Dr. Marc Harwood is already back on the show to discuss this life threatening condition. Rhabdomyolysis can be easily confused with much more benign issues such as dehydration and delayed onset muscle soreness, but rhabdo has a few key distinguishing features. We discuss this crazy situation with the Tufts lacrosse team and give some insight on how to recognize and treat this serious condition.

In this episode, Dennis discusses the role of sodium bicarbonate in medical protocols, particularly in the context of rhabdomyolysis and hyperkalemia. He emphasizes the importance of fluid management and the potential over-hyping of bicarbonate as a treatment. The conversation explores the risks associated with rhabdomyolysis, the mechanisms of potassium management, and the clinical considerations for bicarbonate use in critical care settings. Takeaways Sodium bicarbonate is often over-hyped in medical treatments. Rhabdomyolysis can lead to serious kidney damage. Immediate fluid administration is crucial in suspected rhabdo cases. Bicarbonate has not shown clinical benefits in trials. Managing potassium levels is essential in rhabdomyolysis treatment. Insulin can help drive potassium back into cells. Urine output is a key indicator in treatment effectiveness. Alkalizing urine may not significantly prevent kidney injury. Correcting pH can be important in severe shock situations. Bicarbonate should be used judiciously in critical care. Thank you to Delta Development Team for in part, sponsoring this podcast. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠deltadevteam.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For more content go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.prolongedfieldcare.org⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠ Consider supporting us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/ProlongedFieldCareCollective⁠⁠⁠⁠⁠⁠ or ⁠⁠⁠⁠⁠⁠www.lobocoffeeco.com/product-page/prolonged-field-care⁠

Welcome back to A Stride Above! In today's episode, Dr. Alberto Rullan discusses Equine Rhabdomyolysis, commonly known as “tying up” or the “Monday morning disease.” This condition can essentially leave horses extremely tight and sometimes unable to move, leading to concerns about muscle breakdown.In this episode you'll learn about: • What Equine Rhabdomyolysis is and how it affects horse muscle function, causing stiffness and immobility.• All the various types of tying up, ranging from severe cases where horses can't move to milder cases with slight stiffness.• What treatment options are available, including IV fluids, anti-inflammatories, and sedation to help manage severe cases.• How taking preventative measures, including stress reduction strategies and medications like dantrolene, can help manage the risk of this condition. If you'd like to learn even more or have any further questions regarding Equine Rhabdomyolysis also known as Tying-Up disease, visit https://www.albertorullan.com/ for more information! Be sure to subscribe, follow and rate this podcast- we appreciate immensely! See you back here next week for more helpful tips and guidance on improving the mindful care of your horse's health.Links For You:• Our Website • Facebook • Instagram • Youtube Dr. Alberto Rullan, VMD• Website• LinkedIn• Instagram

"How can athletes effectively return to their sport or physical activities after significant injuries like back pain from snatches, hip replacements, or severe conditions like Rhabdomyolysis, and what are the best practices for re-engaging without recurring injuries?" Got a burning question? Simply subscribe to the Never Zero Newsletter, respond to any of the emails, and ask away.  Tune in every Wednesday to hear Jason Khalipa and Gabe Yanez answer your questions on Apple Podcasts & Spotify. Never Zero Newsletter Follow the Pod Follow Jason Follow Gabe Get the TRAIN HARD App The Ready State NCFIT Programming For Gym Owners

AKI Tips and Tricks from Joel Topf MD, Kashlak's Chief of Nephrology Get a grip on acute kidney injury (AKI) with Dr. Joel Topf (AKA @kidney_boy), Kashlak's Chief of Nephrology! We've put together an AKI highlight reel - focusing on practical tips and tricks to help you identify, diagnose and manage AKI, plus how to recognize AIN and random myths and musings on vancomycin, NSAIDS, contrast nephropathy, and the risk of NSF from gadolinium. Listeners can claim Free CE credit through VCU Health at http://curbsiders.vcuhealth.org/ (CME goes live at 0900 ET on the episode's release date).  Show Notes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME! Credits Written (including CME questions) and Produced by: Cyrus Askin, MD Infographic by: Cyrus Askin, MD Cover Art: Kate Grant MBChb, MRCGP Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Editor: Matthew Watto MD, FACP (written materials); Clair Morgan of nodderly.com Guest: Joel Topf, MD Time Stamps 00:00 Sponsors - VCU Health CE and Pediatrics On Call podcast by APP 00:30 Intro, disclaimer, guest bio 03:00 Guest one-liner, Picks of the Week*: Zoe Keating albums (Cellist); Mrs. America (TV series) on FX; The Last of Us (Videogame); 08:45 Sponsor - Pediatrics On Call podcast by APP 09:15 Definition of acute kidney injury (AKI) and fundamentals 11:00 Cardiorenal syndrome 12:24 Schema for AKI 17:30 Establish an etiology, determine urine output and address electrolyte abnormalities 21:22 AKI in the otherwise-healthy patient; 32:20 Rhabdomyolysis
38:21 Vancomycin 41:43 Acute interstitial nephritis (AIN) 44:52 Contrast induced nephropathy (CIN) 50:37 Gadolinium in AKI and/or CKD 52:53 Timing of dialysis 
 56:37 AKI in the out-patient setting and how to handle home meds e.g. TMP-SMX, RAAS inhibitors; 62:01 Is Ultrasound necessary in AKI
 64:58 Dr. Topf's take home points and Plug for Seminars in Nephrology 68:45 Outro and Sponsor - VCU Health CE Sponsor: Freed You can try Freed for free right now by going to freed.ai. And listeners of Curbsiders can use code CURB50 for $50 off their first month. Sponsor: Panacea Financial If you're ready to join the thousands of doctors who have declared independence from traditional banks, visit panaceafinancial.com today. Sponsor: Locumstory Tune in to The Locumstory Podcast on Spotify, Apple, or Google podcasts.

Ever wondered how muscle breakdown during your workouts could turn deadly? Tune in for an enlightening discussion with Dr. Chris Perry, an ER physician and head of the ICU in Jersey, as we uncover the complexities of rhabdomyolysis. Whether you're a trainer, fitness enthusiast, or just someone keen to understand the health risks of overexertion, this episode promises essential insights. Dr. Perry breaks down the biochemical intricacies and warning signs of rhabdo, emphasizing the importance of recognizing the boundaries between beneficial exercise and harmful strain.We also share cautionary tales like that of "Rabdo Randy," whose intense workout regimen landed him in the hospital with critically high creatine kinase levels. Learn why hydration is more than just a buzzword and how it plays a crucial role in preventing serious conditions like heat-related illnesses and rhabdomyolysis. Plus, we underscore the importance of lifelong learning in the fitness world, urging listeners to step outside their comfort zones and continuously seek knowledge. This episode is a must-listen for anyone committed to a safe and informed fitness journey.Want to ask us a question? Email email info@showupfitness.com with the subject line PODCAST QUESTION to get your question answered live on the show! Our Instagram: https://www.instagram.com/showupfitnessinternship/?hl=enTikTok: https://www.tiktok.com/@showupfitnessinternshipWebsite: https://www.showupfitness.com/Become a Personal Trainer Book (Amazon): https://www.amazon.com/How-Become-Personal-Trainer-Successful/dp/B08WS992F8Show Up Fitness Internship & CPT: https://online.showupfitness.com/pages/online-show-up?utm_term=show%20up%20fitnessNASM study guide: ...

What if seeking help was just a disguise for craving attention? In this Debrief style episode of the Podcast starts with an intriguing probe into the real intentions behind our interactions, inspired by Mark Manson's eye-opening newsletter. We reflect on the crucial traits of mentally strong individuals as outlined by Boosted Brands, stressing the importance of embracing change, taking calculated risks, and prioritizing action over empty chatter. Our goal is to help you transform every conversation into a meaningful exchange that fosters genuine growth and progress.Imagine running so hard you end up in the hospital. That's precisely what happened to Phil Daru, who faced severe foot injuries and Rhabdo after pushing his limits. We explore the concept of the Backwards Law, which suggests that sometimes, the harder we try, the worse the outcome. Using Navy SEAL training as a backdrop, we discuss how relaxing and letting go can sometimes lead to better results. Learn the art of giving fewer f&%ks about uncontrollable factors and discover how this mindset can help you achieve your goals more effectively.Starting a business without being fully prepared—wise or reckless? We dive into Alex Hormozi's provocative advice to launch before you're ready, igniting a spirited debate on the balance between preparedness and action. Alongside, we discuss the dangers of over-systematization with real-life anecdotes, advocating for practical and cost-effective solutions.And much, much more! Send us a Text Message.

In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Rhabdomyolysis⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Renal section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets

You should read her Yelp Review! Meet Thao! This funny lady is a walking ray of sunshine with her half-glass-full attitude. After learning she had advanced aging ovaries that would hinder her dream of motherhood, she opted to go the fertility treatment route. With multiple viable embryos, she chose to gift others and put them up for adoption. Through the twists and turns of life, losing a job while raising twins, and becoming very sick with Rhabdomyolysis she discovers her husband is having an affair. Walking through motherhood with a sense of humor has kept her on top of her mommy game!    Listen today! Like, follow and share. 

Listen as Dr. London Smith (.com) and his producer Cameron discuss Rhabdomyolysis as they share all about their Party Tips. Not so boring! https://www.patreon.com/join/jockdocpodcast Hosts: London Smith, Cameron Clark. Produced by: Dylan Walker Created by: London Smith

Did you listen to Joey's story in last week's mystery episode? If you did and guessed rhabdomyolysis as his diagnosis, congratulations! Joey's muscle injury from playing a little too hard at football camp resulted in a release of muscle proteins that ultimately caused his kidneys to shut down, which led to his diagnosis and treatment for rhabdomyolysis.In this episode, host Sarah Lorenzini examines the complexities of the condition, from its pathophysiology to causes and treatment options. You'll learn the hallmark signs of rhabdomyolysis, the not so obvious signs and symptoms to be aware of, and what to consider when caring for patients.Tune in for a detailed exploration of rhabdomyolysis!Mentioned in this episode:Rapid Response Academy LinkWanna check out Rapid Response Academy: The Heart and Science of Caring for the Sick? click this link to learn more: https://www.rapidresponseandrescue.com/communityRapid Response and Rescue Intro CourseCONNECT

This episode covers rhabdomyolysis.Written notes can be found at https://zerotofinals.com/medicine/renal/rhabdomyolysis/ or in the renal medicine section of the 2nd edition of the Zero to Finals medicine book.The audio in the episode was expertly edited by Harry Watchman.

In this captivating episode, we dive into the extraordinary life of Larry Wheels, a remarkable individual who's not only conquered the realms of bodybuilding, powerlifting, strongman and arm wrestling but has also taken the social media world by storm. Larry opens up about his journey, from being a teenage powerlifting prodigy to evolving into a multifaceted entertainer, influencer, and budding entrepreneur. In this hour-long interview, we explore Larry's candid reflections on his early use of performance-enhancing substances, shedding light on the challenges and lessons learned. As he shares his experiences, Larry also imparts invaluable wisdom for aspiring youth looking up to him, highlighting the importance of making informed decisions. The episode kicks off with Larry discussing his recent hospitalization due to a health scare involving Rhabdomyolysis, offering a raw and real glimpse into his life beyond the spotlight. Tune in for a conversation that goes beyond the surface, aiming to inspire and educate on "The Higher Standard." Also, please note, Saied was on vacation and only Chris and Haroon were present for the interview. Saied is still very salty about it, please don't mention it to him. This is our secret. Larry's Links:Larry Wheels WebsiteLarry's YouTube Channel Larry's InstagramLarry's Threads Larry's FacebookLarry's TwitterLarry's TikTokLarry's SnapchatLarry's Brands:PR LifestylePump & Power Meal PrepTranscend CompanyDisclaimer: Please note that the content shared on this show is solely for entertainment purposes and should not be considered legal or investment advice or attributed to any company. The views and opinions expressed are personal and not reflective of any entity. We do not guarantee the accuracy or completeness of the information provided, and listeners are urged to seek professional advice before making any legal or financial decisions. By listening to The Higher Standard podcast you agree to these terms, and the show, its hosts and employees are not liable for any consequences arising from your use of the content.

Question-based Discussion of risk factors, workup and management of rhabdomyolysis.

Episode 95 dives into what DOMS and “Rhabdo” really are and how improper recovery can be very detrimental to your goals as well as your daily life, and I share a personal story of mine of where I was diagnosed with Rhabomyolysis --- Send in a voice message: https://podcasters.spotify.com/pod/show/primalarmor/message Support this podcast: https://podcasters.spotify.com/pod/show/primalarmor/support

In this episode, Martin welcomes content creator, backpacker, and family-man, Dan Becker to share his personal experience with Rhabdomyolysis (pronounced “rab-doe-my-ah-luh-suhs”) during his rim-to-rim-to-rim ( R2R2R) in the Grand Canyon . Tune-in to learn more. Follow Dan on IG and YouTube: Dan Becker (@danbeckeroutdoors) • Instagram photos and videosDan Becker - YouTubeSupport the showGet outside, have fun and be safe!Martin Armitage, Host of the Papa Bear Hikes Podcasthttps://www.papabearhikes.com/https://podcasts.apple.com/us/podcast/papa-bear-hikes/id1541491746https://www.instagram.com/papabearhikes01/

João Urbano e Tiago discutem sobre diagnóstico de tratamento de rabdomiólise.

Dr Tamara Hew-Butler is a podiatric physician and associate professor of Exercise and Sports Science at Wayne State University in Detroit, Michigan. Topics of this episode include hydration, internal and external load, salt intake and combining the art of coaching with science. Timestamps: Tamara's background (1:40) Tamara's thoughts and preferences about internal and external load (4:21) Athlete with Rhabdomyolysis - who is responsible and why does it happen? (6:47) Dangers of overhydration for athletes (9:02) Was there backlash from the episode of “Adam Ruins Everything - Why You Don't Need 8 Glasses of Water a Day”? (13:18) How did the “Adam Ruins Everything”- show find Tamara? (14:27) What liquids are the athletes having on the sideline of Wayne State Football? (16:39) If there would be an unlimited budget, what liquids Tamara would get for athletes? (17:26) Is players drinking pickle juice still a thing? (18:37) Training adjustments after pandemic and combining the art of coaching with science (20:16) Working with the new Football coach Tyrone Wheatley at Wayne State University (26:56) The reason why WSU Football got Firstbeat (27:34) Firstbeat Quick Recovery Test trends over the years (31:00) The most useful Firstbeat features and metrics for WSU Football (31:56) Analysis of different TRIMP values from last year to this year (32:50) Adam Ruins Everything - Why You Don't Need 8 Glasses of Water a Day

Hiking the Appalachian Trail? No big deal. Hiking the Appalachian Trail, contracting Rhabdomyolysis, then finishing the rest of the multi-day hike? That's a different story.

In this episode we discuss a listener question submitted, touching on a recent article from Outside Online.  We touch on collpase and cardiac issues in marathons, rhabdomyolysis and precipitators and other factors involved in general overtraining.    Show Notes: Article submitted with listener question-  https://www.outsideonline.com/health/running/culture-running/people/on-his-way-to-a-pr-a-marathoner-collapsed-at-mile-26/  Go Fund Me- https://www.gofundme.com/f/k5ss4-aarons-fund?utm_campaign=p_cp+share-sheet&utm_content=undefined&utm_medium=copy_link_all&utm_source=customer&utm_term=undefined  Article on Rhabdomyolysis- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365849/  Upper Respiratory Tract Infection in Athletes -  https://www.mdpi.com/2079-7737/10/5/362  Overtraining -  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435910/  RED-S -  https://bjsm.bmj.com/content/52/11/687 

This week Nancy and Kate discuss the tying up syndrome (RER) that appears to affect 8.4% of racehorses. Research Reference: https://www.nzsap.org/system/files/proceedings/trainers-perceptions-impact-different-feeding-and-management-practices-racehorses-they-identified.pdf Wood , LJ, Lancaster, B, Breheny, MR & Rogers, CW 2020, 'Trainers perceptions of the impact of different feeding and management practices on racehorses they identified displaying symptoms of recurrent exertional rhabdomyolysis', Proceedings of the New Zealand Society of Animal Production, vol. 80, pp. 90- 94. --- Send in a voice message: https://anchor.fm/nancy-mclean/message Support this podcast: https://anchor.fm/nancy-mclean/support

Rhabdomyolysis is a condition in which skeletal muscle cells break down and leak their contents into the extracellular space and bloodstream. I usually saw this complex condition in the MICU due to patients who were “found down” and had been lying in one position, completely immobile, for extended periods of time. In this episode you'll learn: The causes of rhabdomyolysis (there are a lot!) Pathophysiology Rhabdomyolysis complications Signs and symptoms of rhabdomyolysis Key assessments Lab tests used to diagnose and monitor the condition Treatments Important education components This is a complex topic with a lot to know, so check out the downloadable study guide that goes along with this lesson. Learn how to get your Power Guide here. Want to maximize your learning by reading this information, too? Check out the article and references here. RATE, REVIEW AND FOLLOW! If this episode helped you, please take a moment to rate and review the show! This helps others find the podcast, which helps me help even more people :-) Click here, scroll to the bottom, then simply tap to rate with 5 stars and select, "write a review." I'd love to hear how the podcast has helped you! If you're not following yet, what are you waiting for? It takes just a quick moment and the episodes show up like magic every Thursday. And, when I release a bonus episode, those show up, too! You'll never miss a thing! In Apple Podcasts, just click on the three little dots in the upper right corner here. Know someone who would also love to study with me? Share the show or share specific episodes with your classmates...when we all work together, we all succeed! On Apple Podcasts, the SHARE link is in the same drop-down as the follow link. Spread the love! Thanks for studying with me! Nurse Mo

Want to experience the greatest in board studying? Check out our interactive question bank podcast- the FIRST of its kind here: emrapidbombs.supercast.com. Iltifat and Blake tackle this ACEP PEER Board Question on Rhabdomyolysis and simplify this disease into just 2 critical management pearls. It doesn't have to be so complicated... Oh, and mannitol and furosemide aren't part of it in case you were wondering. Cite this podcast as: Briggs, Blake; Husain, Iltifat. Episode 150: Rhabdomyolysis: it doesn't have to be complicated. https://www.emboardbombs.com/podcasts/150-rhabdomyolysis-it-doesnt-have-to-be-complicated. October 17th, 2022. Accessed [date]

In this episode, we review the etiologies, diagnosis, investigations and management of rhabdomyolysis. Written by: Dr. Dhruv Krishnan, Internal Medicine ResidentReviewed by: Dr. Audrey Tran (General Internist) and Dr. Samuel Silver (Nephrologist)Sound Editing: Alison Lai

Welcome to PICU Doc On Call, A Podcast Dedicated to Current and Aspiring Intensivists. I'm Pradip Kama and I'm Rahul Damania, a third-year PICU fellow. I'm Kate Phelps, a second-year PICU fellow and we are all coming to you from Children's Healthcare of Atlanta, Emory University School of Medicine, joining Pradip and Rahul today. Welcome to our episode, where will be discussing rhabdomyolysis and associated acute kidney injury in the ICU. Rahul: Here's the case, a 7-year-old female presents to the ED with three days of fever, poor PO, and diffuse myalgia. In the ED, her vital signs are T 39.1C, HR 139, BP 82/44, RR 32. She is pale and diaphoretic, complaining weakly about how much her legs hurt. Her parents note that she has not been peeing very well since yesterday, and when she does pee it is “very concentrated, almost brown.” She's also been spending all her time on the couch and has asked to be carried to the bathroom when she does need to go. An IV is placed by the emergency room team, and she is given a fluid bolus, acetaminophen, and initial labs are drawn (CMP, CBC, RSV/Flu swab) before she is admitted to the PICU. In the PICU, her fever is better and her vitals have improved to T 37.7, HR 119, BP 115/70, and RR 25. Her respiratory swab has just resulted positive for Influenza A. Further labs are sent, including creatine kinase (CK), coagulation studies, and a urinalysis. Labs are notable for K 3.9, Bicarb 22, BUN 15, Cr 0.8, and CK 5768 IU/L. Her urinalysis is notable for 1 WBC, 2 RBC, +3 blood, negative nitrites, and leukocyte esterase. Kate: To summarize key elements from this case, this patient has: Influenza A, as evidenced by her respiratory swab, as well as her clinical prodrome. She has diffuse myalgias, as well as fevers, diaphoresis, and hypotension. Labs are most notable for elevated creatinine and elevated creatine kinase, as well as an abnormal urinalysis. All of which brings up a concern for rhabdomyolysis and myoglobin-induced acute kidney injury. Before we get into this episode — let's create a mental framework for this episode — we will dissect our case by highlighting key H&P components, visit a differential diagnosis, pivot to speaking about pathophysiology, and finally, speak about management! Rahul: Let's transition into some history and physical exam components of this case. The classic presentation of rhabdomyolysis is myalgias, muscle weakness, and tea-colored urine, all of which our patient has. Decreased urinary output can also accompany, a variety of reasons, but most notably if the patient has myoglobin-induced acute kidney injury. In our patient, poor PO is also probably contributing to her decrease in urine output. Red flag signs or symptoms will include anuria, hypotension, and altered mental status (which is rare but may indicate severe acidemia and deterioration) Pradip: As we think about our case, what other disease processes might be in our differential? As we dive in a bit more, we'll come up with ways to distinguish between rhabdo and other things! Viral myositis - inflammation in the muscles in the setting of a viral illness, which can definitely happen with influenza and other common viruses Some other things which may cause reddish-brown urine, including hematuria, hemoglobinuria, porphyria, some specific foods or drugs (like rifampin, beets, food coloring — even ibuprofen) We also have to investigate a bit more to convince ourselves that our patient's AKI is due to rhabdomyolysis, as it could be from dehydration, sepsis, NSAIDS, etc. Kate: Let's dive further into rhabdomyolysis! Rhabdomyolysis affects over 25,000 adults and children every year. While toxins (including prescription drugs, alcohol, and illicit drugs) and trauma are two common causes of rhabdo in adults (and teens), infections, especially viruses, are the most common cause in young children. Influenza, EBV, and CMV are three most commonly reported. What's the pathophysiology of...

Emergency and Sports Medicine Physician, and combat sport aficionado Dr. Sergio Alvarez, explains wrestlers' drastic weight cutting procedures and their physiologic effects on the body. Rhabdomyolysis, hyperthermia, and in some cases, death, is it worth it just to drop a weight class? Hosted by our M2s: Youssef Aref and Cameron Casillas

Fasting can be an effective tool for weight loss. However if used inappropriately, can result in some not good situations. The patient's situation in this case isn't quite like the intermittent fasting schedules that are popular today. Chubbyemu video: https://youtu.be/nQC_GDTNkQQ Heme Review commentary: https://youtu.be/tWlvWYGztYk Music by Lifeformed Tweet me: https://twitter.com/hemereview IG me: https://instagram.com/hemereview References: Mechanism of hypokalemia in magnesium deficiency. Huang CL, Kuo E. J Am Soc Nephrol. 2007;18:2649–2652. https://pubmed.ncbi.nlm.nih.gov/17804670/ Hypophosphatemia and Rhabdomyolysis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC371889/ A Case of Hemodynamically Unstable Sick Sinus Syndrome Secondary to Refeeding Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148626 Review of the Refeeding Syndrome. January 2006 Nutrition in Clinical Practice 20(6):625-33. EMCrit Refeeding Syndrome https://emcrit.org/ibcc/refeeding/ Refeeding syndrome: what it is, and how to prevent and treat it. BMJ. 2008 Jun 28; 336(7659): 1495–1498. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440847/

Contributor: Sam Killian, MD Educational Pearls: Transaminitis refers to the elevation of transaminases, enzymes of the liver (AST and ALT) Elevation of ALT is relatively specific to the liver, but AST is found in more organs than the liver including the muscle If AST is significantly greater than ALT, consider a musculoskeletal origin such as rhabdomyolysis Transaminitis is not always a liver specific issue References Lala V, Goyal A, Minter DA. Liver Function Tests. [Updated 2021 Aug 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482489/ Lim AK. Abnormal liver function tests associated with severe rhabdomyolysis. World J Gastroenterol. 2020;26(10):1020-1028. doi:10.3748/wjg.v26.i10.1020 Jo KM, Heo NY, Park SH, et al. Serum Aminotransferase Level in Rhabdomyolysis according to Concurrent Liver Disease. Korean J Gastroenterol. 2019;74(4):205-211. doi:10.4166/kjg.2019.74.4.205 Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD   The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.  Donate to EMM today!

This episode covers compartment syndrome.Written notes can be found at https://zerotofinals.com/surgery/orthopaedics/compartmentsyndrome/ or in the orthopaedic section of the Zero to Finals surgery book.The audio in the episode was expertly edited by Harry Watchman.

Rhab-what? Rhabdo. In this episode, I'll tell you about the two times I was sidelined with rhabdo, after enduring CrossFit and TRX workouts. I'll tell you about the science, what to look for, and also what my treatment regimen entailed. Advice? Don't get rhabdo.

Seth Sullivan is 32 years old and lives in Wichita, Kansas. 8 years ago, after an intense CrossFit workout he had “coca-cola” brown urine. Seth had served in the United States Marine Corps, so he went to the VA emergency room. Extremely high myoglobin levels indicated rhabdomyolysis and he needed IV fluids to prevent further kidney damage. Tune in to hear the story of how he got rhabdomyolysis and his experience with the VA healthcare system.