Podcasts about Valproate

Chants of 'shame' were heard during Prime Minister's Questions today, after Rishi Sunak made a cutting remark about trans-rights aimed towards Labour leader, Sir Keir Starmer. The mother of Brianna Ghey was in Parliament today - just days after her daughter's killers were sentenced.Niall Paterson speaks to our political correspondent, Amanda Akass, about the prime minister's comments and the backlash. Also - should the government pay compensation to the thousands of victims who suffered injuries from pelvic mesh implants and the epilepsy drug, Valproate?It follows a new report calling on the government to urgently set up a financial package worth half a billion pounds, after Sky News reported regulators knew of the effects of Valproate since the 1970s but failed to disclose them to patients.Our home editor, Jason Farrell, looks at the prospects the victims have of receiving compensation, and the damage caused by the scandal. Podcast producers: Alex Edden and Sydney Pead Assistant producer: Evan Dale Interviews producer: Melissa Tutesigensi-Charles Promotions Producer: Jonathan Day Editor: Paul Stanworth

Also: Wildfires in Chile, torrential rain in California. And One year on from the Turkey/Syria earthquake.

A patient's perspective can ensure safe medical care and lead to new insights that traditional research may overlook. But how do we best harness that perspective to improve patient outcomes?This episode is part of the Uppsala Reports Long Reads series – the most topical stories from UMC's pharmacovigilance news site, brought to you in audio format. Find the original article here.After the read, we speak to Manal Younus, who authored the article, to learn more about patient engagement and its benefits for medicines safety.Tune in to find out:How regulators and healthcare professionals can effectively engage patientsHow patients can get involved in drug safety monitoringWhat the pharmacovigilance community learned from the valproate caseWant to know more?In 2022, the Council for International Organizations of Medical Sciences (CIOMS) published a comprehensive report on patient involvement in the development, regulation and safe use of medicines. They also recorded a webinar to summarise the report's main conclusions.The International Society of Pharmacovigilance (ISoP) runs a patient engagement group to advance patient involvement in the safety monitoring of medicines.The Valproate toolkit, developed by the UK's Medicines and Healthcare Products Regulatory Agency (MHRA), supports healthcare professionals in advising women of childbearing age about the risks and benefits of valproate therapy.PatientsLikeMe is a digital platform where patients can share personal health stories, connect to peers, and learn about different conditions and treatments.For more on patient engagement and communication, check out these episodes from the Drug Safety Matters archive:Why we should listen to patientsThe challenge of rare diseasesHow to talk about risksFinally, don't forget to ­subscribe to the monthly Uppsala Reports newsletter for free regular updates from the world of pharmacovigilance.Join the conversation on social mediaFollow us on Twitter, Facebook or LinkedIn and share your thoughts about the show with the hashtag #DrugSafetyMatters.Got a story to share?We're always looking for new content and interesting people to interview. If you have a great idea for a show, get in touch!About UMCRead more about Uppsala Monitoring Centre and how we work to advance medicines safety.

Updates from the 2023 International Bipolar Conference: Avoid valproate (Depakote) in women of childbearing age; who to blame when patients are noncompliant; and functioning trumps symptom reduction.CME: Take the CME Post-Test for this EpisodePublished On: 08/28/2023Duration: 12 minutes, 20 secondsChris Aiken, MD, and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

In this podcast, Dr. Jon Cole - an emergency medicine physician with Hennepin Healthcare and medical director with Minnesota Poison Control Center and Samantha Lee, PharmD - managing director with Minnesota Poison Control Center discuss the poison control system - past and present; along with a disscusion around toxicology - the big, the bad, and the ugly. Enjoy the podcast. Objectives:Upon completion of this podcast, participants should be able to: Describe the purpose of the Minnesota Poison Control Center, and how it works. Name the most common call types coming into MN Poison Control Center. Summarize the management of toxicological exposures for APAP, bupropion and calcium channel blockers. CME credit is only offered to Ridgeview Providers & Allied Health staff for this podcast activity. After listening to the podcast, complete and submit the online evaluation form.  Upon successful completion of the evaluation, you will be e-mailed a certificate of completion within approximately 2 weeks. You may contact the accredited provider with questions regarding this program at Education@ridgeviewmedical.org. Click the link below, to complete the activity's evaluation. CME Evaluation (**If you are listening to the podcasts through iTunes on your laptop or desktop, it is not possible to link directly with the CME Evaluation for unclear reasons. We are trying to remedy this. You can, however, link to the survey through the Podcasts app on your Apple and other smart devices, as well as through Spotify, Stitcher and other podcast directory apps and on your computer browser at these websites. We apologize for the inconvenience.)  DISCLOSURE ANNOUNCEMENT  The information provided through this and all Ridgeview podcasts as well as any and all accompanying files, images, videos and documents is/are for CME/CE and other institutional learning and communication purposes only and is/are not meant to substitute for the independent medical judgment of a physician, healthcare provider or other healthcare personnel relative to diagnostic and treatment options of a specific patient's medical condition; and are property/rights of Ridgeview Medical Center & Clinics.  Any re-reproduction of any of the materials presented would be infringement of copyright laws.  It is Ridgeview's intent that any potential conflict should be identified openly so that the listeners may form their own judgments about the presentation with the full disclosure of the facts. It is not assumed any potential conflicts will have an adverse impact on these presentations. It remains for the audience to determine whether the speaker's outside interest may reflect a possible bias, either the exposition or the conclusions presented. Ridgeview's CME planning committee members and presenter(s) have disclosed they have no significant financial relationship with a pharmaceutical company and have disclosed that no conflict of interest exists with the presentation/educational event. Thank-you for listening to the podcast. SHOW NOTES:  *See the attachment for additional information.  HISTORY of MN POISON CONTROL CENTER TOXICOLOGYCalcium Channel Blockers - Diltiazem, Verapamil, Amlodipine - Causes bad distributive shock - Pulmonary edema is an issue - Norepinephrine infusion is recommended in setting of shock with high dose insulin simultaneously - "Red, white and blue" therapy for refractory Ca++ blocker overdose - Activated charcoal - not for all patients, give if patient not at risk of aspiration for potentially lethal ingestions Bupropion - Chemical structure similar to amphetamine and bath salts - Sympathomimetic effects (tachycardia, agitation, seizures, ultimately cardiogenic shock) - Treatment with benzodiazepines - usually high dose - may need intubation - Norepinephrine for cardiogenic shock - ECMO may be needed Sodium Nitrite - Salt used to cure meats - Internet suicide phenomenon - Effect: Life threatening methemoglobinemia (chocolate colored blood, pallor, low O2 sats) - Very rapid onset of symptoms - Methylene Blue use N-acetylcysteine (NAC) for acetaminophen poisoning - Transitioning from 3 bag Prescott regimen to a 2 bag regimen - Rumack-Matthew nomogram is the same Article Resources:Cole JB, Lee SC, Prekker ME, Kunzler NM, Considine KA, Driver BE, Puskarich MA, Olives TD. Vasodilation in patients with calcium channel blocker poisoning treated with high-dose insulin: a comparison of amlodipine versus non-dihydropyridines. Clin Toxicol (Phila). 2022 Nov;60(11):1205-1213. doi: 10.1080/15563650.2022.2131565. Epub 2022 Oct 25. PMID: 36282196.   Cole JB, Olives TD, Ulici A, Litell JM, Bangh SA, Arens AM, Puskarich MA, Prekker ME. Extracorporeal Membrane Oxygenation for Poisonings Reported to U.S. Poison Centers from 2000 to 2018: An Analysis of the National Poison Data System. Crit Care Med. 2020 Aug;48(8):1111-1119. doi: 10.1097/CCM.0000000000004401. PMID: 32697480. Coralic Z, Kapur J, Olson KR, Chamberlain JM, Overbeek D, Silbergleit R. Treatment of Toxin-Related Status Epilepticus With Levetiracetam, Fosphenytoin, or Valproate in Patients Enrolled in the Established Status Epilepticus Treatment Trial. Ann Emerg Med. 2022 Sep;80(3):194-202. doi: 10.1016/j.annemergmed.2022.04.020. Epub 2022 Jun 17. PMID: 35718575. Kline JA, Tomaszewski CA, Schroeder JD, Raymond RM. Insulin is a superior antidote for cardiovascular toxicity induced by verapamil in the anesthetized canine. J Pharmacol Exp Ther. 1993 Nov;267(2):744-50. PMID: 8246150.   Thanks to Dr. Jon Cole and Samantha Lee, PharmD for their knowledge and contribution to this podcast. Please check out the additional show notes for more information/resources.

Is the NHS really working in the best interests of your sick child? Ethan's story, as told by his devoted mum, will make you think differently. Read the write-up at: https://www.ukcolumn.org/video/ethans-story-sodium-valproate

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the January 2023 issue of DTB. They begin with another reminder of the concerns over the use of sodium valproate. They talk about the closure of NPS MedicineWise in Australia and the uncertainty over the future of Australian Prescriber - https://dtb.bmj.com/content/61/1/2. They highlight the risk of eye problems with dupilumab - https://dtb.bmj.com/content/61/1/6 (see more links below) and the challenge of making sure that primary care clinical systems record drugs prescribed by specialists. They discuss toxocarosis in humans and the risk of environmental contamination from parasiticides used for deworming cats and dogs (https://dtb.bmj.com/content/61/1/3 and https://dtb.bmj.com/content/61/1/7). Dupilumab links: 1. Reji MA, Haque A, Goyal S, et al. Dupilumab-induced ocular surface disease: a primer. BMJ Case Reports CP 2022;15:e249019. https://casereports.bmj.com/content/15/4/e249019 2. Nahum Y, Mimouni M, Livny E, et al. Dupilumab-induced ocular surface disease (DIOSD) in patients with atopic dermatitis: clinical presentation, risk factors for development and outcomes of treatment with tacrolimus ointment. British Journal of Ophthalmology 2020;104:776-9. https://bjo.bmj.com/content/104/6/776 The contact address for the DTB team is dtb@bmj.com. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

Contributor: Travis Barlock, MD Educational Pearls: The causes of pancreatitis can be remembered with the mnemonic: “GET SMASHED”  G: Gallstones (Most common cause of pancreatitis overall)  E: Ethanol (Alcohol consumption is the most common cause of chronic pancreatitis) T: Trauma  S: Steroids M: Malignancy A: Autoimmune  S: Scorpion Sting H: Hypertryglyceridemia  E: ERCP D: Drugs (e.g. Valproate, Antiretrovirals)    References Beyer G, Habtezion A, Werner J, Lerch MM, Mayerle J. Chronic pancreatitis. Lancet. 2020;396(10249):499-512. doi:10.1016/S0140-6736(20)31318-0 Lankisch PG, Apte M, Banks PA. Acute pancreatitis [published correction appears in Lancet. 2015 Nov 21;386(10008):2058]. Lancet. 2015;386(9988):85-96. doi:10.1016/S0140-6736(14)60649-8   Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, & Erik Verzemnieks, MD   In an effort to promote diversity, equity, and inclusion in Emergency Medicine, The Emergency Medical Minute is proud to present our 2nd annual Diversity and Inclusion Award. We support increasing the representation of underrepresented groups in medicine and extend this award to individuals applying to emergency medicine residencies during the 2022-2023 cycle. For information on award eligibility and the application process, visit https://emergencymedicalminute.com/edi-award/ Donate to EMM today!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.09.519825v1?rss=1 Authors: Cintado, M. A., Gonzalez-Tirado, G., Carcel, L., De la Casa, L. G. Abstract: In three experiments with rats, we analyzed the potential anxiolytic effects of sodium valproate, an anticonvulsant drug that has shown additional pharmacodynamic effects in animal models, including anxiolytic action. Since previous results have revealed that injecting valproate before allowing animals to consume a novel flavor solution resulted in an attenuation of neophobia, we predicted a similar effect when the novel flavor is presented on a drug-free trial in the presence of a context previously associated with the drug. In line with this hypothesis, in our first experiment we observed a reduction in neophobia to a novel flavor for those animals tested in the presence of the context associated with Sodium Valproate. However, a control group that received the drug before being allowed access to the novel flavor showed a significant reduction in consumption. Experiment 2 revealed that the unconditioned effects of the drug include a deleterious effect on the animals' locomotor activity that probably interferes with drinking behavior. Finally, in a third experiment, we directly tested the potential anxiolytic properties of sodium valproate by injecting the drug before implementing a fear conditioning procedure. These findings are explained in terms of the unconditioned anxiolytic action of the drug and the formation of an association between the context and the effects of the drug that evokes a conditioned response reminiscent of such anxiolytic effect. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.21.517445v1?rss=1 Authors: sukumaran, s., M, S., Iyer, S., Banerjee, A., Purushottam, M., Jain, S., Viswanath, B., Sud, R. Abstract: Adults with bipolar disorder or epileptic seizures are commonly prescribed sodium valproate. In utero exposure to this drug is linked to a multitude of defects in normal brain development, from neural tube defects to autism spectrum disorders. During the course of brain development, neural precursor cells (NPCs) give rise to neurons and glia, and therefore to understand the valproate-induced defects, it is crucial to understand its effect on NPCs. Two NPC lines, both derived from healthy individuals, were used for all experiments. Cells were treated with 0.7mM valproate for one week. Fresh media (+/- drug) was replenished every alternate day. RNA was extracted on day 7 of drug treatment, and transcriptomics performed. All experiments were performed in biological replicates. Genes that showed greater than 1-fold difference (with FDR adjusted q-value less than or equal to 0.05) were considered differentially expressed. We further investigated the interacting partners of the differentially expressed genes using PINOT, as well as cellular pathways using DAVID. Our primary endpoint of analysis were genes that were differentially expressed (DEGs) with valproate treatment in both the NPC lines used. We found 21 such genes that were common in the two lines. PINOT revealed 504 interacting partners of the DEGs. Functional annotation analysis showed significant enrichment of four signaling pathways - Wnt, Notch, Rho-GTPase and PI3K-AKT. While the role of Rho-GTPase is a novel finding, we have replicated previously reported findings on Wnt, Notch and PI3K-Akt pathways, which further strengthens their role in mediating neurodevelopmental anomalies. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Theme: Neurology. Participants: Dr Hugo Morales (neurologist), Dr James Tadros (emergency physician), Jessica Stabler (epilepsy fellow), Kim Van Vu, Mariez Gorgi and Shreyas Iyer. Discussion:Chamberlain, J., Kapur, J., Shinnar, S., Elm, J., Holsti, M., & Babcock, L. et al. (2020). Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. The Lancet, 395(10231), 1217-1224. https://doi.org/10.1016/s0140-6736(20)30611-5. Presenter: Jessica StablerMusic/Sound Effects: Help You Out by Leonell Cassio ft. Jonathon Robins | https://soundcloud.com/leonellcassio, Music promoted by https://www.free-stock-music.com, Creative Commons Attribution-ShareAlike 3.0 Unported, https://creativecommons.org/licenses/by-sa/3.0/deed.en_US.  Nightswim by Scandinavianz | https://soundcloud.com/scandinavianz, Music promoted by https://www.free-stock-music.comCreative Commons Attribution 3.0 Unported License, https://creativecommons.org/licenses/by/3.0/deed.en_US. Ocean Love by LiQWYD | https://www.liqwydmusic.com, Music promoted by https://www.free-stock-music.com, Creative Commons Attribution 3.0 Unported License, https://creativecommons.org/licenses/by/3.0/deed.en_US. River by MusicbyAden | https://soundcloud.com/musicbyaden, Music promoted by https://www.free-stock-music.com, Creative Commons Attribution-ShareAlike 3.0 Unported, https://creativecommons.org/licenses/by-sa/3.0/deed.en_US. Slipz (audio logo) by tubebackr | https://soundcloud.com/tubebackr, Music promoted by https://www.free-stock-music.com. Sound effects from https://www.free-stock-music.com.  The Travelling Symphony by Savfk | https://www.youtube.com/savfkmusic, Music promoted by https://www.free-stock-music.comAttribution 4.0 International (CC BY 4.0), https://creativecommons.org/licenses/by/4.0/.  Thank you for listening!Please send us an email to let us know what you thought.You can contact us at westmeadedjournalclub@gmail.com.You can also follow us on Facebook, Instagram, and Twitter!See you next time!~

I dive deep into four general categories of medications that are often prescribed for people living with dementia: antidepressants, mood stabilizers, benzodiazepines (spoiler alert--not a good option), and antipsychotics. Learn why these medications are prescribed and what problems may happen when your family member takes them. This information is for educational use only. Consult your healthcare professional before making any medication changes. I hope that this information assists you with having conversations about medications with your healthcare provider. Here are the studies I mention: Seitz DP, Adunuri N, Gill SS, Gruneir A, Herrmann N, Rochon P. Antidepressants for agitation and psychosis in dementia. Cochrane Database of Systematic Reviews. 2011(2). McCleery J, Cohen DA, Sharpley AL. Pharmacotherapies for sleep disturbances in dementia. Cochrane Database Syst Rev. 2016;11:CD009178. Baillon SF, Narayana U, Luxenberg JS, Clifton AV. Valproate preparations for agitation in dementia. Cochrane Database Syst Rev. 2018;10:CD003945. PODCAST CHALLENGE! · Rate and review my podcast on your favorite platform · E-mail me a screenshot before Friday, March 11 at 5 pm central time US; if you want to game the system and rate and review on multiple platforms, go for it! Email: rita.jablonski@gmail.com · 3 winners will receive a signed, autographed copy of my book · Winners will be announced during Episode 37 (which will be dropped Sunday, March 13 2022) CHECK OUT MY BOOK! “Make Dementia Your B*tch! An Easy Guide to Understanding and Handling Dementia-driven Behaviors.” Have a dementia question? Want to hear it answered on a future podcast? Email me: rita.jablonski@gmail.com. Are you a visual learning? Check out my YouTube channel, where I demonstrate strategies like bridging and chaining Looking for a community? I have my own Facebook page for dementia caregivers: Make Dementia Your B! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/rita-a-jablonski/message

At Wisconsin Institute of Functional Medicine we strive to help our patients with natural solutions to thinning hair and hair loss. We will share with you the types of peptides, compounds, and PRP procedures that can help restore your hair; making it thicker, fuller, and even longer. You don't have to settle for thinning hair and bald spots. There are pre-treatment protocols that are researched and proven to help. Did you know your immune system plays a role in growing healthy hair? Learn more! We also give you the tools and information on how to maintain your new growth so it lasts! I bet you haven't heard of PTD-DMB along with a derma roller to help hair growth. Valproate with Latanoprost to maximize your hair follicle's ability to create new hair and it even works better than Minoxidil. Plus GHK-CU/Zinc thymulin shampoo along with a scalp exfoliator to remove build-up on the scalp, and open the hair follicle. This will allow copper & zinc, which is usually deficient, to nourish your hair follicle. PRP will bring blood flow to the scalp along with growth factors to create beautiful healthy hair. For more information, visit my website at https://wisconsinfunctionalmed.com/ I'd really appreciate it if you would click the like button above and leave a review if your favorite podcast app has that ability. Thank you! © 2021 Tracy Page, MD

This episode discusses valproate kinetics and sublinear kinetics, valproic acid levels, its absolute contraindications, and what to consider when using the package insert. Faculty: Jonathan Meyer, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about Premium Membership here Earn 1 CME: Use of Psychotropics in Patients With Hepatic Issues Valproate/Divalproex: Metabolism, Kinetics, and Warnings

Who is responsible for pre conception care? How can you optimise the health of a mother and baby if you only meet them at 16 weeks of pregnancy?https://www.npeu.ox.ac.uk/assets/downloads/mbrrace-uk/reports/maternal-report-2020/MBRRACE-UK_Maternal_Report_2020_-_Lay_Summary_v10.pdfMedicines and pregnancy & Valproate information:https://www.youtube.com/watch?v=VuBq2M1Me04https://www.medicinesinpregnancy.org/Planning a pregnancy?https://www.nhs.uk/pregnancy/trying-for-a-baby/planning-your-pregnancy/Pregnancy and being overweighthttps://www.rcog.org.uk/globalassets/documents/patients/patient-information-leaflets/pregnancy/pi-being-overweight-during-pregnancy-and-after-birth-002.pdfhttps://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.15386You can find out more about me on Twitter @FWmaternity & @TheObsPod as well as Instagram @TheObsPod please check out #MatExp matexp.org.uk for ideas about how to improve maternity experience.    My beautiful artwork is thank to Anna Geyer www.newpossibilities.co.uk

We just finished recording our Live Sunday Special. Martin and I were joined by investigative journalist with Noteworthy, Maria Delaney to discuss her recent story about the ongoing Valproate scandal. Full story HERE We were also joined by Dr Sharon Lambert, but unfortunately we had some WiFi issues! We discussed the shrinking bank market, tax haven Ireland, public servant pay rises, Leo Varadkar interviewed under caution, vaccine kite flying and the new contract in Public Health. Maybe consider supporting Noteworthy HERE. Thanks for joining us and we hope to see you next week by joining us at patreon.com/tortoiseshack

We just finished recording our Live Sunday Special. Martin and I were joined by investigative journalist with Noteworthy, Maria Delaney to discuss her recent story about the ongoing Valproate scandal. Full story HERE We were also joined by Dr Sharon Lambert, but unfortunately we had some WiFi issues! We discussed the shrinking bank market, tax haven Ireland, public servant pay rises, Leo Varadkar interviewed under caution, vaccine kite flying and the new contract in Public Health. Maybe consider supporting Noteworthy HERE. Thanks for joining us and we hope to see you next week by joining us at patreon.com/tortoiseshack

Meet Dr. Jim Morrow, a former Neurologist from Northern Ireland, with whom we are talking about Sodium Valproate, aka Epilim, its feature in the UK Government's "Cumberlege Review", and why it has been called a "public health scandal" by some.Sodium Valproate is a medicine commonly used to treat epilepsy (and bipolar actually) and has been around since the 1960s. You'll find it referred to mainly as Valproate in this podcast.**CHECK OUT JIM**• BMJ: https://pn.bmj.com/content/16/2/162• Belfast Telegraph: https://www.belfasttelegraph.co.uk/news/health/belfast-doctor-who-earned-global-reputation-for-treating-epilepsy-found-he-had-condition-himself-36706294.html• Epilepsy Action: https://www.epilepsy.org.uk/news/news/dr-jim-morrow-receives-special-recognition-award-outstanding-contribution-treatment**CHECK OUT THE YOUTUBE VIDEO WITH JIM**• YouTube: https://www.youtube.com/watch?v=xd1Jt12x27g&t=586s**CONNECT WITH TORIE**• Website:https://www.torierobinson.com• Twitter:https://twitter.com/torierobinson10• LinkedIn:https://www.linkedin.com/torierobinson• Facebook: https://www.facebook.com/TorieRobinsonSpeaker **CHECK OUT TORIE'S YOUTUBE & BLOG**• YouTube: https://www.youtube.com/c/TorieRobinson• Blog: https://www.torierobinson.com/blog**HIRE TORIE AS A SPEAKER ON EPILEPSY, MENTAL HEALTH, DISABILITY, & DIVERSITY & INCLUSION**https://www.torierobinson.com/contact

Dr. Bradley Vines: "We did a project where we were interested in neuroplasticity and music. Neuroplasticity is related to so many mental health issues stroke and depression which is related to certain patterns that develop in the brain".Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12)#2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07)#3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09)#4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08)#5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53)#6 Can music replace psychedelic drugs? (37:36)#7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06)Dr.Bradley VinesChief Science Officer at Wavepathshttps://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30)#3 Semantic Audio Analysis and Music Recognition Explained. (13:25)#4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22)#5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40)#6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26)#7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19)#8 Is a Universal Music Taxonomy Possible? (38:57)#9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13)#10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation OfficerMusimapwww.musimap.netHost:

Dr. Bradley Vines: "It can be very therapeutic to engage in creating music and then listening to music. It is going to be beneficial for us and our health".Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12)#2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07)#3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09)#4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08)#5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53)#6 Can music replace psychedelic drugs? (37:36)#7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06)Dr.Bradley VinesChief Science Officer at Wavepathshttps://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30)#3 Semantic Audio Analysis and Music Recognition Explained. (13:25)#4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22)#5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40)#6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26)#7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19)#8 Is a Universal Music Taxonomy Possible? (38:57)#9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13)#10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation OfficerMusimapwww.musimap.netHost:

Dr. Bradley Vines: "Can you imagine a music system that's tuned in to what you need and that can deliver music that's just suited for arriving at a desired state of mind and experience. That is really helpful, beneficial and interesting".Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12)#2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07)#3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09)#4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08)#5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53)#6 Can music replace psychedelic drugs? (37:36)#7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06)Dr.Bradley VinesChief Science Officer at Wavepathshttps://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30)#3 Semantic Audio Analysis and Music Recognition Explained. (13:25)#4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22)#5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40)#6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26)#7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19)#8 Is a Universal Music Taxonomy Possible? (38:57)#9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13)#10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation OfficerMusimapwww.musimap.netHost:

Dr. Bradley Vines: "So his insight was that music is playing an incredibly powerful role. You can even look at psychedelic therapy as a kind of music therapy that enables music to do even more than it would normally".Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12)#2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07)#3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09)#4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08)#5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53)#6 Can music replace psychedelic drugs? (37:36)#7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06)Dr.Bradley VinesChief Science Officer at Wavepathshttps://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30)#3 Semantic Audio Analysis and Music Recognition Explained. (13:25)#4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22)#5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40)#6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26)#7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19)#8 Is a Universal Music Taxonomy Possible? (38:57)#9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13)#10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation OfficerMusimapwww.musimap.netHost:

Dr. Bradley Vines: "Whereas with music this is something that the person is experiencing continuously. They will hear this even if they're not paying attention to it. It is a very helpful way to influence mood and to create calm, or to support different emotional states. That is why music is so very powerful".Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12)#2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07)#3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09)#4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08)#5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53)#6 Can music replace psychedelic drugs? (37:36)#7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06)Dr.Bradley VinesChief Science Officer at Wavepathshttps://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30)#3 Semantic Audio Analysis and Music Recognition Explained. (13:25)#4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22)#5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40)#6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26)#7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19)#8 Is a Universal Music Taxonomy Possible? (38:57)#9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13)#10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation OfficerMusimapwww.musimap.netHost:

Dr. Bradley Vines: "Throughout human history we know about the power of music and that brings us to the point of how can we use data to really move the needle, so we can use music to make intelligent decisions in this moment".Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12)#2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07)#3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09)#4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08)#5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53)#6 Can music replace psychedelic drugs? (37:36)#7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06)Dr.Bradley VinesChief Science Officer at Wavepathshttps://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30)#3 Semantic Audio Analysis and Music Recognition Explained. (13:25)#4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22)#5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40)#6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26)#7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19)#8 Is a Universal Music Taxonomy Possible? (38:57)#9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13)#10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation OfficerMusimapwww.musimap.netHost:

Dr. Bradley Vines: "What's usually non-conscious has become conscious. Now we are burdened with having to think consciously about all kinds of things we just took for granted before, whether to sit the stand or sit down, whether to shake hands or not".Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12)#2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07)#3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09)#4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08)#5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53)#6 Can music replace psychedelic drugs? (37:36)#7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06)Dr.Bradley VinesChief Science Officer at Wavepathshttps://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30)#3 Semantic Audio Analysis and Music Recognition Explained. (13:25)#4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22)#5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40)#6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26)#7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19)#8 Is a Universal Music Taxonomy Possible? (38:57)#9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13)#10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation OfficerMusimapwww.musimap.netHost:

In episode #2 of my podcast I spoke with Dr. Bradley Vines regarding his work in the field of sonic branding at Nielsen Consumer Neuroscience. Today, Dr. Bradley Vines is the Chief Science Officer at Wavepaths focusing on music in psychedelic therapy. On top of his long list of merited Universities, Dr Bradley Vines has been Laboratory Director at the University of British Columbia in the Department of Psychiatry's Institute of Mental Health In this episode, Bradley and I discuss the ins and outs of the role music plays in psychedelic therapy. Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 5: Music as medicine: - How Wavepaths's integration of AI, neuroscience and psychotherapy is unlocking the healing effect of music to design the future of mental health.#1 Covid-19 is burdening our mental health with having to think consciously about behaviors we took for granted. (02:12) #2 Research study: Absolute pitch and neuroplasticity: Valproate significantly improved adults' perfect pitch performance. (07:07) #3 Traditional mental health treatments vs. music in psychedelic therapy. (12:09) #4 How Wavepaths's AI music system delivers personalised, adaptive, therapeutic experiences with music for psychedelic therapy. (21:08) #5 How to train an AI- system to deliver tailored music that leads a person into a desired mental state. (33:53) #6 Can music replace psychedelic drugs? (37:36) #7 Self-medicating through music during quarantine – Listen, Sing, Play. (49:06) Dr.Bradley VinesChief Science Officer at Wavepaths https://www.wavepaths.com/My guest today is my friend Thomas Lidy. We met in Athens 2018, when I was involved in the European Horizon 2020 research project FuturePulse through Soundtrack Your Brand. Thomas is from Vienna Austria and has been active in semantic audio analysis and AI-based music recognition since 2004. He has a Master of Science and has pursued a PhD in computer science (which he has not finished, though) from Vienna University of Technology, where he also started his research career, focusing on Music Information Retrieval.Listen to the entire podcast or vlog: The Power of Audio + Science + AI with Jasmine Moradi (https://www.jasminemoradi.com, Spotify, Apple Music & Google Play) Episode 6: Musimap's Emotional AI: - Decoding the DNA of music by combining human emotions and AI to gain insight into music consumption.Soundbites#1 How Thomas Lidy's Combined Passion for Computers and Music Brought Him to Become one of the World's Top Experts in Music AI. (03:42 )#2 How FuturePulse is Empowering the Music Industry with Predictive Analytics on Artists, Tracks, Playlists and Genres with just a Few Clicks. (05:30) #3 Semantic Audio Analysis and Music Recognition Explained. (13:25) #4 Bridging the Gap Between Academia and Industry: Vienna University of Technology - Music Information Retrieval Research - Spectralmind #Music Bricks - Musimap. (18:22) #5 The Successful Foundation of the Belgian B2B Music AI Company Musimap is Backed by 20 years of Human Research Combined with Audio-Processing and AI.(23:40) #6 Becoming the “Ultimate Music Assistant” by Scientifically Decoding the DNA of Music. (26:26) #7 A“Humanized” Algorithm = a Human Fused AI + Feedback Loops. (34:19) #8 Is a Universal Music Taxonomy Possible? (38:57) #9 MusiMe: You are What You Listen to. Your Spotify Playlists Reveal Your Personality. Try it Out. https://yawylt.musimap.io/(45:13) #10 How Emotional Artificial Intelligence Music is Revolutionizing Audio Branding, E-Commerce and the Dating Industry. (54:11)Thomas LidyChief Innovation Officer Musimapwww.musimap.netHost:

Paddy McGeoghan communications officer with Epilepsy Ireland talks to Karl Fenlon about the effects of Sodium Valproate on pregnant women. Broadcast: 09/07/2020

On this edition of the Sky News Daily podcast with Gillian Joseph, we examine the outcome of the independent review into the pregnancy hormone drug, vaginal mesh and an epilepsy drug.We are joined by our home affairs editor Jason Farrell, Yvette Greenway-Mansfield - who had pelvic mesh fitted in 2009 - and Labour MP Yasmin Qureshi, chair of the parliamentary group campaigning for Primodos survivors.Credits:Producer - Annie JoyceAssistant producer - Sabah Choudhry

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.31.126227v1?rss=1 Authors: Li, Q., Li, Q.-Q., Jia, J.-N., Liu, Z.-Q., Zhou, H.-H., Jin, W.-L., Mao, X.-Y. Abstract: Background and purpose: Epilepsy is a chronic neurological disease that is characterized by repetitive seizures. Seizures-related complications such as cognitive deficits, anxiety and sleep disorders seriously impact the life quality of patients. Antiepileptic drugs are widely used for the treatment of epilepsy. Sodium valproate is served as the first-line antiepileptic drugs and possesses various pharmacological effects on the brain. Sodium valproate exerts neuroprotective effects in acute nervous system diseases such as ischemic brain damage by inhibiting oxidative stress. However, the mechanism of neuroprotection of sodium valproate in epilepsy is unclear. Lysyl oxidase (Lox) is a monoamine oxidase that acts on extracellular matrix collagen and elastin and it can promote accumulation of oxidative stress. Our previous studies have confirmed that Lox is involved in ferroptosis, a novel iron-dependent and lipid peroxidation-mediated cell death pathway, during epilepsy. In this study, we would like to investigate whether sodium valproate can exert neuroprotective effects on kainic acid-induced epileptic seizures by inhibiting Lox-mediated ferroptosis. Methods: Epileptic mouse models were established by intracranial injection of 250 ng/l kainic acid on right hippocampus. Sodium valproate and ferroptosis inhibitors were administrated by intraperitoneal injecting. The epileptic behavior of the mice within 4 hours was recorded after intracranial injection of kainic acid. Mouse hippocampus was acquired to analyze the mRNA expression of prostaglandin-endoperoxide synthase 2 (PTGS2) and the production of 4-hydroxynonenal (4-HNE). In vitro, the protective effects of sodium valproate on glutamate-induced HT22 cell damage model was assessed by PI/Hoechst staining; The levels of PTGS2, 4-HNE and lipid ROS were analyzed by RT-qPCR, western blot and flow cytometry, respectively. RT-qPCR and Western blot analysis the mRNA and protein expression of Lox in the glutamate-induced HT22 cell damage model. The Lox overexpression model was established by intracranial injection of AAV on right hippocampus. Results: Pretreatment with sodium valproate and ferroptosis inhibitors could significantly alleviate the epileptic seizures in the kainic acid induced epilepsy mouse model. Western blot and RT-qPCR results showed that sodium valproate and ferroptosis inhibitors significantly inhibited the levels of 4-HNE and PTGS2. PI/Hoechst staining showed that 1 mM sodium valproate exerted protective effect on glutamate-induced HT22 cell injury model. There was no significant difference observed between sodium valproate and ferroptosis inhibitors co-intervention group and sodium valproate intervention group on glutamate-induced cell injury model. And sodium valproate could significantly inhibit the production of lipid reactive oxygen species and 4-HNE. The expression of Lox was significantly increased in the glutamate-induced HT22 cell injury model, which could be reversed by pretreatment of sodium valproate. And {beta}-aminopropionitrile (a specific inhibitor of Lox) could inhibit ferroptosis induced by glutamate, as well as ameliorate the epileptic seizures in the kainic acid induced epilepsy mouse model. Pretreatment with sodium valproate could not ameliorate the epileptic behavior in the Lox-overexpression mice. Western blot analysis showed that sodium valproate could not suppress the production of 4-HNE in kainic acid induced epileptic mice model. Conclusions: The neuroprotective effect of sodium valproate in epileptic seizures is closely related to the inhibition of ferroptosis. The inhibition of ferroptosis is involved in the neuroprotective effect of sodium valproate on glutamate-induced HT22 cell damage model. Sodium valproate may exert neuroprotective effects in kainic acid-induced epileptic seizures by abrogating Lox-mediated ferroptosis. Copy rights belong to original authors. Visit the link for more info

Staying healthy during quarantine? How about mixing ketodiet with valproate? That'll definitely be trending... Join us for

In this episode I cover epilepsy.If you want to follow along with written notes on epilepsy go to https://zerotofinals.com/medicine/neurology/epilepsy/ or the neurology section in the Zero to Finals medicine book.This episode covers pathophysiology, presentation, types, diagnosis and management of epilepsy. The audio in the episode was expertly edited by Harry Watchman.

Valproate (valproic acid, Depakote) has numerous uses which includes migraines, seizures, and bipolar disorder. In a patient who is taking valproate, it is important to monitor for signs and symptoms of confusion as this drug can cause elevated ammonia levels. When switching between dosage forms of valproate, you must recognize that the bioavailability is not the same between each different dosage form. This could lead to toxicity or treatment failure. Valproic acid has a boxed warning for hepatotoxicity and liver function needs to be monitored. Valproic acid can increase lamotrigine levels which ultimately could lead to an increased risk of lamotrigine induced SJS.

In this episode, Dr. Madrid discusses commonly prescribed medications which can cause and contribute to weight gain. Is it possible your doctor is contributing to your weight gain? Dr. Madrid also discusses some alternatives to these medications. Diabetes drugs which cause weight gain: 1. Insulin- Long acting and short acting formulations 2. Thiazolidinediones. – rosiglitazone, poglitazone (actos) 3. Sulfonylureas – glipizide, glimepiride and glyburide Alternatives? Metformin, Liraglutide and dulaglutide can assist with weight loss Depression/Anxiety: 1. Antidepressant drugs like amitriptyline, paroxetine, sertraline and mirtazapine (Remeron) frequently cause weight gain.. *Alternatives to ask your doctor about include reducing the dose of the medication, especially if it is working for you. Some find that fluoxetine, and buproprion (Wellbutrin) help with weight loss. St. Johns wort is an herbal equivalent with no affect on weight. Blood pressure-reducing drugs: 1. beta-blockers (metoprolol, atenolol, carvedilol) slow down metabolism/heart rate, and increase weight. Alternatives: ace inhibitors, ARBs and Calcium Channel blockers. Seizure disorders/epilepsy drugs; 1. Valproate and carbamazepine Steroid hormone drugs: 1. Prednisone and birth control pills are associated with weight gain. Inhaled steroids, used for asthma/copd is not associated with weight gain. Bipolar and schizophrenia drugs: Antipsychotic drugs such as haloperidol, clozapine, lithium, dulaglutide and liraglutide. Instagram: @ericmadridmd Twitter: @ericmadridmd Facebook: facebook.com/ericmadridmd DISCLAIMER: This podcast is not intended to provide a diagnosis, treatment or medical advice. Opinions by Dr. Madrid are for INFORMATIONAL purposes only. Please consult with your physician regarding your situation as each person is unique.

Valproate is now contraindicated in pregnancy and women of child-bearing potential. The new stipulations from the Coordination Group for Mutual Recognition and Decentralised Procedures-Human (CMDh), a regulatory body representing European Union member states, about the use of valproate in women of child-bearing potential states that “Valproate should never be started unless alternative treatments are not suitable”. However, people taking this drug used to treat epilepsy should not stop valproate use abruptly, without consulting their doctor. The new regulations are discussed in this podcast by Professor Sanjay Sisodiya (UCL Institute of Neurology, London), who’s the author of a Practical Neurology editorial on this subject (http://pn.bmj.com/content/early/2018/04/19/practneurol-2018-001955). Other related articles in the Practical Neurology website: ►http://pn.bmj.com/content/early/2018/04/19/practneurol-2018-001932 ► http://pn.bmj.com/content/early/2018/04/19/practneurol-2018-001931

We apologize to our listeners for our show being late this week. We are coming to you directly from the Exploring Psychedelics Conference at Southern Oregon University, and preparations and travel have slowed down the release of this week's episode. On Today's Episode of the podcast, Jonathan talks with Jon Bridge. Jon is  a 34 year old father of two. from Canada. The two met through a Facebook Group, The Terence McKenna Experience, thanks to Jon's willingness to share his inspiring story of hope and healing. Jonathan felt called to respond almost immediately after the posting appeared on his feed, and the two connected to share Jon's story. Jon's experience of the failure of standard  psychiatricpharmaceutical drugs  and his journey back to health with the help of psilocybin mushrooms and a clear understanding that the conditions that ailed him for years did not have to be permanent, or simply "managed" with ill-understood collections of molecules. Jon [I was on] daily doses of high strength, high dose pharmaceutical garbage. I was supposed to be a customer for life. Although I have no credentials behind my name I have a story of healing and hope. I had been a long time sufferer of mental illness but thanks to psychedelic medicines I have discovered a new, better self. My journey into psychedelic healing has just begun and I hope to be able to inspire someone to help themselves. Jon's "before" picture, on the let, is dated March 20, 2010, exactly 6 years before the date of his Facebook post..Looking in the eyes, it feels possible to almost see the changed interior landscape behind them. This is a story that our listeners will not want to miss. (None of Jon or Jonathan's remarks should be interpreted as psychiatric advice. Neither is a licensed therapist. Changes in medicines should be done with the partnership of a qualified professional.) Thanks to everyone who "Liked" Psychedelic Parenting on Facebook and helped us reach our goal of 1000 page likes by the end of March. As of 3/31/16 at 11:59pm, we had 1017 page likes! Thanks again to all who clicked, shared or clickshared... And, as always, if you like what you see and hear, please consider a tax-deductible contribution to the work. Help us keep the podcast streaming and the website improving! Click the purple button below to contribute to Psychedelic Parenting via MAPS Click HERE to join our mailing list or become a part of our "Secret" Facebook discussion group. TOPICS AND WEBSITES DISCUSSED IN THIS EPISODE: Exploring Psychedelics Conference Home Page Facebook Page Grateful Meds Dispensary, Talent, Oregon Home Page Oregon Cannabis Connections: "Third Grateful Meds Dispensary Opens in Talent" Pharmeceutical Products Cyprolex (Generic: Escitalopram) Tryptophan Lithium Seroquel (Generic: Quetiapine) Wellbutrin (Generic: Bupropion) Citalopram (Brand Names: Celexa, Cipramil) Divalproex (Valporate) Stopping Psychiatric Drugs  For specific dangers and symptoms and helpful guidelines for coming off psychotropics, see Coming off Psychiatric Medication  Ketamine Erowid.org page WebMD: "Ketamine: The Future of Depression Treatment?" ClinicalTrials.gov: "Rapid Antidepressant Effects of Ketamine in Major Depression" Vice.com: "I Used Ketamine to Treat My Depression" Ketamine Advocacy Network: "Provider Directory" Dextromethorphan ("DXM") Erowid.org: "DXM Vault" Psilocybin Erowid.org: "Psilocybin Mushroom Vault" Vice.com: "What it Feels Like to Treat Depression with Magic Mushrooms" New York Times: "Can Mushrooms Treat Depression?" The New Yorker: "The Trip Treatment" By Michael Pollan Mixing Psilocybin and Cannabis (as Jon describes in his story) Shroomery.org forums: "Cannabis and Mushrooms" Erowid Experience Vaults: "Rendered Eternal, Mushrooms and Cannabis" Santa as Shaman When Santa Was a Shaman: Ancient Origins of Santa Claus and the Christmas Tree  by Tony van Renterghem NPR.org: "Did 'Shrooms Send Santa and his Reindeer Flying?" Reality Sandwich: "Shaman Claus: The Shamanic Origins of Christmas" Plenty of Fish (POF) Free Online Dating Service

Today in FirstWord:

Editor's Audio Summary by Howard Bauchner, MD, Editor in Chief of JAMA, the Journal of the American Medical Association, for the April 24, 2013 issue

Interview with Jakob Christensen, PhD, author of Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

In a special episode of Epilepsy.com's Hallway Conversations, Dr. Joseph Sirven, Professor of Neurology at Mayo Clinic Arizona and Editor-in-Chief of Epilepsy.com/Professionals, interviews Dr. Kimford Meador from Emory University. Dr. Meador will discuss a recently published study in The New England Journal of Medicine on the topic of valproate (Depakote) taken during pregnancy and its link to lower IQs in children. This is a live taping with no questions to be answered live.

Motor impairments of psychiatric patients can be assessed with digital recordings of handwriting tasks. The investigation of patients with bipolar affective disorders differentiates intraindividual changes related to the patient's fluctuating affective states. An unmedicated 67-year-old male with 48-hour bipolar ultrarapid cycling was investigated during 8 consecutive days of ultrarapid cycling and 4 weeks later, after remission under treatment with valproate. The handwriting skills of the patient followed the same rhythmic changes of the psychopathology in the first part of the study and a steady pattern in the second phase, after remission. Therefore, it can be assumed that the handwriting skills reflect a state marker of the disease. Poorer handwriting skills on the manic days, as compared to the depressive ones, support the hypothesis of a low arousal in manic patients. Copyright (C) 2000 S. Karger AG, Basel.

We investigated the effect of sodium valproate on plasma ACTH and serum cortisol concentrations in different pathological states of ACTH hypersecretion. Five patients with pituitary dependent Cushing's syndrome, two patients with Nelson's syndrome and five patients with Addison's disease were studied. Neither a single dose nor long term administration of sodium valproate resulted in a significant decrease of plasma ACTH levels in patients with Cushing's disease and Nelson's syndrome. Furthermore, the response of ACTH and cortisol to stimulation with lysine-vasopressin was unaffected during acute and chronic treatment. Patients with Addison's disease showed a slight attenuation of the ACTH response to lysine-vasopressin as compared to placebo but the difference was not statistically significant. In conclusion: sodium valproate does not appear to be effective in controlling ACTH hypersecretion in pituitary dependent Cushing's syndrome.