Podcasts about pb2

Following King Aegon II's coronation and the death of Queen Rhaenyra's son, House Targaryen is divided in two. In King's Landing, Aegon II rules from the Iron Throne, supported by Alicent and the Green Council. From exile on Dragonstone, Queen Rhaenyra and her Black Council consider their next move. House Rivera has thoughts! AAWA, The Boys are up their ol' hi jinx yet again, lazering crotches, hatching plans and manipulating the media like it was going out of style (it ain't), meanwhile Charlie digs Point Break up out out of the sand to give us his PB2 elevator pitch!

听众朋友们大家好，欢迎收听雪球出品的追基零距离，雪球，国内领先的集投资交流交易一体的综合财富管理平台，聪明的投资者都在这里。今天分享的内容叫互联网的春天要来吗？来自米多多笔记。春节前，互联网一波飙涨80%。很多小伙伴都回本了，有的还大赚。然而春节后，互联网再次萎靡，一波跌去20%+，互联网好不容易雄起，为啥又颓了？一是前期反弹太快。短短几个月，互联网翻倍的股票比比皆是，获利盘太大，一有风吹草动就砸盘出逃。二是近期宏观风险加大，互联网根基不稳，只能跌跌不休。比如对经济的预期，从强复苏切换到弱复苏，老米加息预期反复横跳，欧美银行炸雷，金融风险大增，全球股市都很差。不过互联网还在山脚下，大幅调整后，又可以积极关注，等待入手的机会。近期互联网财报出来了，给大家缕一缕。首先，互联网主旋律还是降本。腾讯去年四季度总营收1449亿，调整后净利润297亿，利润率超过20%，依然是强大的赚钱机器。业绩不仅持续企稳，隐约还有反转的迹象。总体上，广告和游戏出海是亮点，特别是广告，一举扭转连续下滑的颓势，非常难得。一方面受益经济重启，商家恢复广告投放，表明企鹅对商家粘性极强。另一方面视频号非常给力，用户和时长延续高增，逐步成为新的增长点。腾讯有强大稳固的基本盘，垄断社交，游戏独大，支付坐稳两强。今年国内经济复苏，这些业务都会受益，叠加游戏版号重开、视频号高歌猛进，腾讯营收端大概率恢复增长动力。过去两年互联网过冬，普遍压缩开支，盈利效率大幅提升。一旦营收重回增长，利润增长将更快，业绩反转可期。阿里去年四季度收入2477亿，同比微增2%，净利润499亿，同比增长11.9%。各板块中，淘系电商继续颓，阿里云增速远低于行业。自营稳健增长，但利润率低。国际电商和菜鸟增速较高，但规模尚小且未盈利，短期难以贡献业绩增量。市场更关心的是淘系和阿里云，前者是基本盘，后者是二次起飞的希望。不过电商卷麻了，淘系份额持续被蚕食，阿里云也面临激烈竞争。尽管如此，阿里还是电商一哥，赚钱能力依然不俗，去年自由现金流达到815亿，有足够的现金完成Q4回购33亿美元的计划。国内经济复苏，电商大盘持续扩张，淘系也会受益。但稳住份额，或找到新的增长点，更加关键。其他巨头同样面临增长压力，比如百度去年四季度收入331亿，同比零增长，京东去年四季度收入2954亿，同比仅增长7.1%。拼多多和美团好一点。拼多多调整后净利润121亿，同比大增43%，完成了从烧钱大户到单季豪赚百亿的华丽逆袭。美团本地商业地位稳固，四季度收入601亿，同增21%，依然保有不错的成长性，不过最赚钱的到店被抖音内卷，利润率有所下滑。综合大厂业绩，营收端面临困境，利润端却大幅增长。主要是大幅削减成本，省出来的效益。这一点去年第三季度就很明显。不过趋势上，业绩连续两个季度企稳，同时净资产收益率触底回升，盈利能力持续改善。这个信号非常积极，表明业绩底大概率已经探明。过去两年，互联网一直走下坡路，去年更是被各种黑天鹅爆锤，迎来至暗时刻。如果没有变得更差，春天已经不远。其次，互联网增长来自哪？第一，降本增效。互联网都是大块头，稍微勒紧裤腰带，利润就出来了。第二，宏观经济。互联网大头是消费和广告，都和经济挂钩。大环境转好，老百姓收入增长，消费自然就多了，企业赚钱，广告就多了，互联网不愁没增长。更关键的是，政策风向不一样了。今年疫情放开，稳增长政策积极，经济和消费如果持续复苏，互联网有望告别低迷，拐头向上。这将驱动行业营收改善，业绩周期反转。竞争格局越好的赛道，改善越明显。第三，新兴产业。互联网渗透率基本饱和，除了宏观贝塔，新兴业务能带来增量。近期ChatGPT在全球掀起AI风暴，其强大而优异的性能，正在催化AI产业大爆发。强大的AI=庞大的算力+海量的数据+顶尖的算法。这些巨头们都有。据《2023胡润中国数字技术算法算力百强榜》，互联网企业霸榜前10。巨头们有应用场景，能把AI直接落地，拓宽收入来源。百度推出文心一言，很快会融入搜索，企鹅的混元AI、阿里的M6等，都是国内领先的大模型。AI时代，算力就像石油，是核心资源，巨头的云计算（阿里云、腾讯云等）也将深度受益。综合来看，降本总有极限，只有营收端恢复动力，利润才能持续增长。AI想象力巨大，互联网有机会迎来第二春，不过产业尚在初期，实际贡献还很远。中短期还得看宏观脸色。最后，互联网如何操作？经济持续复苏，互联网跟随回暖，业绩大概率反转上行。美国加息终点临近，全球流动性宽松预期升温。两座大山都松动了。互联网前期大反弹，就是反映这种预期，但短期抢跑太多，近期又开始调整。目前行业PB2.7倍，分位值8%，仍处于历史低位。前面两个大逻辑不破，很难像前期那样大跌。不过经济温和复苏，业绩反转需要更多时间，美元宽松也不会一蹴而就，因此连续大涨或走牛也缺少支撑。唯有两者共振，才有确定性机会。过去两年互联网被锤很惨，现在宏观环境改善、基本面企稳，最黑暗的时候已经过去了。但互联网渗透率到顶，成长性不复以往，短期内很难迅速回到原来的高点。需要以新常态的思维看待互联网。如果仓位重成本高，可以考虑波段操作，拉低成本。比如跌的多了，可以补仓，底部反弹一波就逐步减仓。多搞几轮，成本就降下来了。仓位轻的朋友，可拉开间隔定投，控制好仓位不超过10%。有较大反弹时，也可减仓止盈。近期欧美银行暴雷，全球股市波动加大，港股和互联网跟随调整。再跌一跌，多多准备加仓互联网，搞波段降成本。

A perovskita é um mineral de óxido de cálcio e titânio, com a fórmula química CaTiO3. O mineral foi descoberto nos Montes Urais da Rússia por Gustav Rose em 1839 e deve o seu nome ao mineralogista russo Lev Perovski (1792-1856). Devido ao seu potencial de aplicação, as perovskitas tornaram-se um dos materiais mais estudados no momento. Um campo de aplicação especialmente promissor é o da tecnologia fotovoltaica, que trata de dispositivos capazes de converter com eficiência energia luminosa em energia elétrica. A eficiência de conversão apresentada por perovskitas híbridas está hoje em torno de 25,2%, superando a eficiência das células comerciais baseadas na tecnologia do silício. Exemplo de perovskita híbrida é o iodeto de chumbo e metilamônio (CH3NH3PbI3). O material é chamado de “híbrido” porque, em sua molécula, os três íons negativos, constituídos pelo iodo (I-), equilibram um íon positivo inorgânico, constituído pelo chumbo (Pb2+), e um íon positivo orgânico, constituído pelo metilamônio (CH3NH3+). Com foco exatamente no iodeto de chumbo e metilamônio, um estudo conduzido no Departamento de Física e Química da Universidade Estadual Paulista (Unesp), em Ilha Solteira, avançou na compreensão da natureza ferroelétrica e da origem das propriedades fotovoltaicas excepcionais das perovskitas. Artigo a respeito foi publicado na revista Acta Materialia. O estudo faz parte da pesquisa de doutorado de Fernando Brondani Minussi, orientada por Eudes Borges de Araújo, professor titular da Unesp. E contou com apoio da FAPESP por meio do Projeto Temático “Materiais multiferroicos e ferroelétricos para conversores de energia: síntese, propriedades, fenomenologia e aplicações”, coordenado pelo professor José Antonio Eiras, da Universidade Federal de São Carlos (UFSCar), e que tem Araújo como pesquisador principal. “Nesse estudo, investigamos de modo sistemático o efeito da temperatura e de um campo elétrico de corrente contínua sobre as propriedades elétricas, dielétricas e espectroscópicas do iodeto de chumbo e metilamônio. E procuramos excluir outras interferências para demonstrar a assinatura característica do relaxor ferroelétrico na perovskita estudada”, diz Araújo. Os resultados originais e realmente significativos apresentados no estudo em pauta têm potencial para promover mudanças de paradigma na compreensão da natureza ferroelétrica e da origem das propriedades fotovoltaicas excepcionais das perovskitas de haletos. “Acredito que este trabalho traz avanços substanciais para a fundamentação da física desse sistema complexo e fascinante”. Fonte (texto) - créditos: O artigo Effects of frequency, temperature, and dc bias electric field on the dielectric properties of methylammonium lead iodide from the perspective of a relaxor-like ferroelectric pode ser acessado em ww.sciencedirect.com/science/article/abs/pii/S1359645421006157?via%3Dihub. "https://agencia.fapesp.br/grupo-da-unesp-explora-a-fisica-das-perovskitas-materiais-com-grande-potencial-de-aplicacao-tecnologica/36701/" https://www.ecycle.com.br/perovskita/ Imagem (créditos): Cristopher Eames et al. Trilha sonora (créditos): Lobby Time - Kevin MacLeod Audio Library - Free Music (música grátis) - https://www.youtube.com/watch?v=XnusoK_1JOw&list=PLKCo4y0JbV2ZrcJeKQgSWg_93QYAAjpCX&index=29 --- Send in a voice message: https://podcasters.spotify.com/pod/show/multimidiavillage/message

Welcome to #Millennial, the home of pretend adulting and real FIRE talk! Stoves are apparently a hot button (lol) issue, and President Biden continues coming under scrutiny for his classified documents faux pas. Do we believe everything we read in memoirs? Some details in Prince Harry's memoir "Spare" have been determined to be inaccurate. Since human memory is subject to flaws when recalling events, how much stock can we put in any memoir's ability to represent reality? Time to get nerdy: Pam and Laura cover an ongoing story in the Dungeons & Dragons community. Once again, corporations are getting greedy and attempting to screw over their fan base. Swift backlash from the DnD community led to Wizards of the Coast backtracking its new proposed Open Gaming License (OGL), but fans are still wary of what is to come. The Missouri State House of Representatives has adopted stricter dress code guidelines for its female members. Apparently bare arms and shoulders are too scandalous for Missouri.  The United States House of Representatives relaxed its own archaic rules around dress code for women in 2017 - c'mon Missouri, even Paul Ryan thought this was stupid. We reminisce about our own run ins with being dress code violators and check in on our old high schools' current dress code requirements. This week we have a group recommendation: Watch 'The Last of Us' on HBOMax. Just do it. Do it now. (We also have a bonus recommendation for the inevitable zombie apocalypse: PB2 powdered peanut butter!) And in this week's installment of After Dark, available on Patreon: MuggleSuck, The AIM Files (part III). Between being homeschooled and lacking IRL friends, Andrew and Laura really had nothing better to do than be riled up by fansite drama. How did we talk about and perceive being gay in the early 2000s? How does it differ from 2023 standards?

Todays buffet of topics include: Do you want to watch this episode via video over on Instagram? Go HERE Maybelline Lip Stain & Thrive Causemetics Mascara Things we are not loving right now- PB2 and PeScience Vegan Protein YouTuber Mark Plummer, Chalene Johnson Amber Scholl Deload week? Is it necessary? Taping loose skin into your competition suit Should you weight train or cardio if you are over 50? How long should your training block last? Teens and weight lifting How to train your body for what you want it to look like Linda & Lucy the Leptin Losers Mental hunger vs true hunger Pros and cons to gaining weight in the improvement season Why I'm running right now Deodorant for your sweaty body parts Salty Savage Pants HERE Use code: AmandaGlitters Bodybuilding vs. Powerlifting body differences SOME LINKS TO THINGS THAT ARE MY FAVES:   ► NEW CLIENT OFFER==> Want to be trained by the most badass personal training studio in Modesto? First time clients score your sessions at a great deal HERE   ► Get your personalized Physique Assessment done by me HERE   ►The absolute BEST tasting protein bars on the planet: https://bit.ly/BuiltBar Use promo code: Diane to save $$   ► Cortisolve or Vasoburn on MPA Supplements (use promo code: Diane to save $$)   ► Want diet coaching with us? Check out our 12 week diet program #DitchDeprivation   ►Interested in competition coaching?  Check out my website HERE JOIN ME ON INSTAGRAM: @dianeflores_ifbb_pro READ MY BLOG HERE: http://www.livingthegoddesslife.com/ JOIN ME ON FACEBOOK: https://www.facebook.com/dianefloreslivingthegoddesslife TRAIN WITH US IN PERSON HERE: https://www.venusfitnessstudio.com/ INTERESTED IN COMPETITION PREP COACHING? http://bit.ly/GBETWaitlist ***CLICK THE LINKS BELOW TO CHECK OUT MY VIRTUAL PROGRAMS*** ►At home virtual programs: https://bit.ly/DianesDIYVirtualPrograms ►12 Week At Home Workout Program: http://www.livingthegoddesslife.com/goddess-body-at-home/ ►My online Sensual Movement program: https://sensualdancemovement.com/  ►Looking to shop which protein/supplements and things I use on Amazon? https://www.amazon.com/shop/dianeflores_ifbb_pro ► The Best Planner to SMASH your goals here: http://bit.ly/PushJournalGoalPlanner I hope you enjoy this episode and, if you do, please leave a written review on iTunes (huge THANK YOU to everyone who has written one so far).

HTLT releases its first testosterone booster 3 Test featuring a similar formula to Gorilla Mind Sigma, Magic Spoon drops two more options for its crispy and crunchy protein bar, peanut butter powder brand PB2 launches a rather unique pre-workout, and 'Merica Labz reveals its powerhouse, high-stimulant formula powering F-Bomb.

From ASV 2022 in Madison, Wisconsin, TWiV speaks with Pamela Bjorkman and Andy Mehle about their careers and their research on influenza virus, HIV-1, SARS-CoV-2, and influenza virus. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guests: Pamela Bjorkman and Andy Mehle Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Bjorkman laboratory Mehle laboratory Finding the groove (Nat Immunol) Structure of HLA-A2 (Nat Immunol) Mosaic RBD nanoparticles (Science) Influenza virus PB2 627 (J Virol) ANP32B or not to be (eLife) Influenza virus compartmentalization (Nat Commun) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

So many links...no thanks to Jack.Late Afternoon Gaming Subreddit - https://www.reddit.com/search/?q=lateafternoongamingAstral Codex Ten on being quirky - https://astralcodexten.substack.com/p/in-partial-grudging-defense-of-thePhrenology - https://www.britannica.com/topic/phrenologyPredictably Irrational - https://www.amazon.com/dp/B002RI9QJE/ref=dp-kindle-redirect?_encoding=UTF8&btkr=1J.C. Penney Pricing - https://mmrstrategy.com/lessons-in-pricing-strategy-from-jcpenney/#:~:text=JCPenney's%20New%20Pricing%20Strategy&text=By%20contrast%2C%20the%20new%20%E2%80%9CEveryday,were%20used%20when%20pricing%20items.Pizza and Mayo - https://uncutrecipes.com/EN-Recipes-Japanese/Tuna-and-Corn-Pizza-Recipe.html#:~:text=TRADITIONAL%20JAPANESE%20RECIPE%3A%20In%20Japan,really%20put%20Mayo%20on%20pizza.PB2 - https://pb2foods.com/Bender's Cooking - https://www.youtube.com/watch?v=s4uvQRTCdYAGSA Cookies of Yesteryear - https://www.tasteofhome.com/collection/discontinued-girl-scout-cookies/Banana Extinction - https://www.businessinsider.com/cavendish-banana-may-go-extinct-disease-2021-6Holy Cow Ice Cream (Byrne Dairy) - https://www.byrnedairy.com/list-of-ice-cream-flavors/Vanilla = Bland? - https://slate.com/human-interest/2005/08/how-vanilla-became-shorthand-for-bland.html5-Hour LotR Video Game Retrospective - https://www.youtube.com/watch?v=poMnJKLGYo0Unresolved (True Crime Podcasts) - https://www.youtube.com/c/TheunresolvedpodcastMetcalf Sniper Attack - https://www.youtube.com/watch?v=LQpsYTZnnjARed Cell - https://en.wikipedia.org/wiki/Red_Cell

在跑鞋矩阵系列录制期间，各个品牌也在不断地推出自己的新款。尤其是最近，国产品牌更是扎堆召开发布会，热闹非凡。这些跑鞋几乎涵盖了跑者的所有需求，有缓震，有竞速，有路跑，有越野，有之前系列的延伸，也有开疆拓土的新款。在赛季即将开始的这个时间，我们就和大家一起梳理一下，最近新上市的这些跑鞋们。NikeStreakfly：定位5k-10k短距离竞速训练比赛，全掌zoomx+中足尼龙板，重量轻，鞋面柔软，脚感软弹，耐磨一般。AdidasAdistar：定位长距离慢跑，双密度中底，前软后硬，马牌橡胶外底保障防滑耐磨，稳定性好，适合大体重，初跑者，进阶跑者的慢跑及LSD训练。Asicsnimbus24：稳中有升，FFblast+材料更轻更弹，一体织鞋舌包裹性更好。SauconySurge澎湃：国内线产品，平价版胜利（折后819），舒适与稳定兼顾的慢跑款式。Kinvara菁华13：主要改进在于鞋面材质，重量略微减轻。HokaKAWANA：多场景训练鞋，力量、有氧、日常等环境兼顾。CarbonX3：一体织鞋面，据说proflyX是超临界发泡，但有待确认，外媒平价一般，鞋面包裹性欠佳。Speedgoat5：AltraParadigm6：旗舰级缓震，侧墙设计兼顾稳定支撑，脚感扎实，不是宣软的那种缓震。可用于改善跑姿及慢跑。Mont Blanc：定位高缓震轻量化长距离越野，V家litebase外底适应复杂地形。李宁烈骏6：eva鞋床包裹etpu䨻，通过结构设计改变原有稳定支撑跑鞋常见的内侧硬质材料，稳定保护的同时提供舒适脚感，适合大体重，后跟落地的入门跑者。国乔飞影PB2.0：改良鞋面，中底加入peba材料，加宽碳板和后跟，舒适度、回弹力，稳定性都有提升。保持高性价比，低驾驭门槛的特点。飞影2：训练款，后跟内侧支撑设计。风行11：入门款，同样使用巭pro科技，脚感软弹。看似休闲实则能打。361飞飙：前后分离式中底，碳板面积大，硬度高。提高步频提升跑步经济性。飞燃ST：定位为竞训款，全掌碳板，eva超临界发泡材料，适合大众跑者进阶训练。鸿星尔克奇弹 炁：etup发泡，竞速训练及半马比赛。=======================微博 / 小程序 / 服务号：@跑者日历公众号： 跑者日历RUN365 各音频及播客平台：跑者日历=======================应大家的要求，我们终于有了自己的听众群，欢迎各位跑友进群交流。可以通过添加客服微信号：run365cs ，拉你入群。期待你的加入，一起听，一起跑

In this episode, Bobby is joined by Will Knapp! Will is known for posting Eating Disorder Recovery related content on his tiktok account (@okay.will) and has grown nearly 100k followers sharing his journey in ED recovery as a young male. Bobby and Will talk about the stigmas of dealing with an ED as guys, and how they both were able to overcome that stigma in order to create content that helps others in their own recovery. Will also speaks on why he uses PB2 instead of normal PB. You wont want to miss this episode!Follow Will on Tiktok! @okay.willFollow Bobby on Tiktok! @bobbykazz

Force Toast: It's gross, gooey stuff*. But it's stuff. Laura played a trivia match at Schmoedown Collision and she's in AARP now. Those two things aren't related, but now you know.The Banthaverse is coming back soon and it's bringing Alyce with it! And not just any Alyce – Alyce with a beard and laser sword and *checks notes* a Maggie Smith impression?Star Wars: Galactic Starcruiser is coming next year and YIKES we hope you all spent the pandemic building a time machine so you could go back to 1993 and buy Apple stockWatch a roundtable of Imagineers talk about what guests can expect from forthcoming immersive hotel experienceIt's early days still, but we've got a Star Wars Celebration tip for you in this episode Put on your readers, Millennials! Tamagotchis are coming back.Question: What do green beans, grammys and gospel have to do with Star Wars? Answer: this house on ZillowICYMI: Krystina Arielle of The High Republic Show hosts a panel with the 5 Star Wars: The High Republic authors about their next books at SDCC 2021Could Star Wars Jedi: Fallen Order get a sequel? It sounds like that's the planNot to bury the lead, but Star Wars: The Bad Batch is getting a second season! Let's get that time machine back out and take it to 2022!Recap on Tap: The Bad Batch episodes 13, 14 and 15, including SPOILERS! Roland is the Christan Gray of Star Wars, mommy issues and all. Gregor is back and he, like PB2 protein powder, is a bit nutty. Then episode 15 gives us Part 1 of the season finale and it is here to tear you down emotionally and THEN it has THE AUDACITY to make you wait a week to watch Part 2. Get excited for new episodes of Force Toast back to back! We'll drop our next episode on Tuesday, August 17th that will include our discussion about The Bad Batch finale! See you next week! Helpful links referenced in this episode:Schmoedown Collision aired LIVE on YouTube on July 31. The Star Wars match coverage begins around the 1 hour mark.The Return of the Banthaverse is upon us! Star Wars: Episode 2.5 written by A.I. premieres August 14 and will star Alyce as Jedi Master Obi-Wan Kenobi Twitter: @forcetoastpod | @sLeiaAllDay | @ShutUp_LauraInstagram: @forcetoastpodEmail: forcetoastpod@gmail.comWebsite: forcetoastpod.com*This podcast contains a sh!t ton of profanity and boozin. You can find a bleeped version of this podcast absolutely nowhere. Cheers!

we have a group of guys here that share a discord channel, i tend to drop in there myself from time to time and find it fairly pleasent. they have attended a few of our milsoft sundays, and attended PB2 as their first formal milsim as a teamConsider supporting me here:Patreonpaypal.me/travisgoldieleave me a review

Peanut butter is found in nearly every kitchen pantry. But with its high fat content and inherent “messiness”, this staple was missing the trend of people searching for healthier alternatives and higher protein. That is until the invention of powdered peanut butter by PB2. I sat down with Craig Entwistle, CEO at PB2 Foods, to learn more about how the brand is changing the peanut butter category and how they are approaching innovation in growing the business.

At PB2, they believe in finding the balance in everyday life, feeling confident in your choices, and being present each day. PB2 launched in 2007 and is continually working with a family of farmers to create pure and simple products that help you live better and happier. PB2 believes food can be both healthy and delicious at the same time. Eat what you love. Love what you eat. Choose PB2. John Monczynski joins Justin to discuss this delicious brand.

Spelar det någon roll om jag försäkrar min van som personbil klass 1 eller som husbil (PB2)? Vad ska jag tänka på när jag väljer försäkringsbolag och behöver jag verkligen en Assistansförsäkring? Det och mycket mer pratar vi om med juristen Helen Bernerfalk från Konstumenternas Försäkringsbyrå. Otippat spännande och väldigt viktigt avsnitt!

Tips for Healthy Hacks & Tips to Emulate our Favorite Peanut Butter & Chocolate Combination!According to iHeart Radio's 939 Beat, people love this peanut butter & chocolate combination so much because of something called Dynamic Sensory Contrast. Our taste buds love when contrasting flavors come together, and the smoothness of the chocolate and the salty crunch from the peanut butter are a contrasting match made by the gods.This episode will bring you a large list of low-calorie, low-fat, high protein versions of our Heavenly treat!Brands for Healthy Hacks:Walden Farms Zero Calorie ProductsPB2 Powdered Peanut Butter and Chocolate PowdersFage Greek YogurtHershey's Cocoa & Cacao PowderProtein PowdersHELPFUL PRODUCTS:TikTok Butt-Lift LeggingsFood JournalsSelf Help BooksHealthy CookbooksPlus Size FashionsAtomic Habits BookThink Like a Monk BookGet Out of Your Head BookPopular Fitness Products for SuccessLift LeggingsFitness BandsAthleisure WearMassage GunWearable Fitness DevicesWater BottlesHOST ANNE MCDANIELS LINKS:Facebook: Anne McDanielsFacebook: Anne McDaniels ActressInstagram: @annemcdanielsactressInstagram: @annemcdanielsTwitter : @annemcdanielsIMDB : Anne McDanielsClubhouse: @annemcdanielsTikTok: Anne McDanielsClubhouse: @annemcdanielsMusic Credit: Traxis: "Sexy 80's Grind"https://traxis1.bandcamp.com/album/wickedBit-Chute: Traxis Music VideosSpotify: Traxis Playlist https://traxis1.bandcamp.com/Photo Credit: iStockSpecial Credit: Joy Bauer, Pernilla Stryker, Lacy Baier, Lori Occhiogrosso

Drea and Renee conquer three kinds of bread in this episode of Cook It! Working through Black Girl Baking, they cook up two sweet and one savoury! They also talk peanut butter alternatives and the topic of wonky tarts brings up a new cookbook pre-order! PB2 - https://pb2foods.com/ The Wonky Spatula - https://thewonkyspatula.com/

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.31.230904v1?rss=1 Authors: Yin, R., Luo, Z., Zhuang, P., Lin, Z., Kwoh, C. K. Abstract: Motivation: Influenza viruses are persistently threatening public health, causing annual epidemics and sporadic pandemics. The evolution of influenza viruses remains to be the main obstacle in the effectiveness of antiviral treatments due to rapid mutations. Previous work has been investigated to reveal the determinants of virulence of the influenza A virus. To further facilitate flu surveillance, explicit detection of influenza virulence is crucial to protect public health from potential future pandemics. Results: In this paper, we propose a weighted ensemble convolutional neural network for the virulence prediction of influenza A viruses named VirPreNet that uses all 8 segments. Firstly, mouse lethal dose 50 is exerted to label the virulence of infections into two classes, namely avirulent and virulent. A numerical representation of amino acids named ProtVec is applied to the 8-segments in a distributed manner to encode the biological sequences. After splittings and embeddings of influenza strains, the ensemble convolutional neural network is constructed as the base model on the influenza dataset of each segment, which serves as the VirPreNet's main part. Followed by a linear layer, the initial predictive outcomes are integrated and assigned with different weights for the final prediction. The experimental results on the collected influenza dataset indicate that VirPreNet achieves state-of-the-art performance combining ProtVec with our proposed architecture. It outperforms baseline methods on the independent testing data. Moreover, our proposed model reveals the importance of PB2 and HA segments on the virulence prediction. We believe that our model may provide new insights into the investigation of influenza virulence. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.30.181149v1?rss=1 Authors: Schultheiss, N. W., McGlothan, J. L., Guilarte, T. R., Allen, T. A. Abstract: Chronic lead (Pb2+) exposure from childhood contributes to an array of cognitive and behavioral dysfunctions including impaired attention and intellectual ability, learning and memory deficits, and delinquency. It is also an environmental risk factor for adult psychopathologies, most notably schizophrenia. Pb2+ is a potent N-methyl-D-aspartate receptor (NMDAR) antagonist and exposure during early life elicits a cascade of cellular neurotoxic effects that alter the developmental trajectory leading to a loss of parvalbumin-expressing interneurons in hippocampus and altered synaptic transmission. Little is known, however, about the impact of chronic Pb2+ exposure on hippocampal network dynamics which serve as a link between cellular-molecular effects and cognitive-behavioral consequences of Pb2+ neurotoxicity. Here, we tested the effects of chronic Pb2+ exposure on local field potential activity (LFP) in the hippocampus of freely-behaving rats. We demonstrate that Pb2+ exposure causes striking hypersynchrony in both the theta- and gamma-frequency bands, in addition to more modest changes in delta. Next, we tested the effect of Pb2+ exposure on prepulse inhibition of the acoustic startle reflex (PPI) in male and female rats at different developmental timepoints. We found that adult males (PN50 and 120), but neither females nor juvenile males, showed reduced PPI that could not be attributed to changes in the startle reflex. This pattern recapitulates sex- and age-dependencies of PPI disruption in schizophrenic patients. Overall, these results are consistent with the hypothesis that Pb2+ is an environmental risk factor for psychopathology in adulthood, especially those symptoms related to cognitive and sensory-motor gating processes that depend on rhythmic coordination of network activity in the hippocampus. Copy rights belong to original authors. Visit the link for more info

Today's episode is an interview with a California mom and wife who loves to talk about fitness, food and family fun. She is the creator of Yay for Today, a place online where women can find happiness, be inspired to live a healthy life and celebrate fun family moments. She shares food ideas that taste good and make you feel good, fitness tips that will motivate you to move your body and keeps mamahood real with lots of rainbows on her colorful Instagram feed.  On the daily, you can find her sharing all the things on her Instastories, eating her famed snack PB2 powder in vanilla greek yogurt and adventuring Cali with her boys. In our interview, she opens up about her insecurities, haters and failures and talks about how to go about finding the courage to start something new. She shares the source of her inspiration and motivation and her favorite fitness tips. We talk about Alison's Brand School and Brene Brown and have lots of fun getting to know Sidney. You can find her on Instagram at: www.instagram.com/yayfortoday_

Today’s episode is an interview with a California mom and wife who loves to talk about fitness, food and family fun. She is the creator of Yay for Today, a place online where women can find happiness, be inspired to live a healthy life and celebrate fun family moments. She shares food ideas that taste good and make you feel good, fitness tips that will motivate you to move your body and keeps mamahood real with lots of rainbows on her colorful Instagram feed.  On the daily, you can find her sharing all the things on her Instastories, eating her famed snack PB2 powder in vanilla greek yogurt and adventuring Cali with her boys. In our interview, she opens up about her insecurities, haters and failures and talks about how to go about finding the courage to start something new. She shares the source of her inspiration and motivation and her favorite fitness tips. We talk about Alison’s Brand School and Brene Brown and have lots of fun getting to know Sidney. You can find her on Instagram at: www.instagram.com/yayfortoday_ (http://www.instagram.com/yayfortoday_)

  Thank you for tuning in to Episode 118 of the Down Cellar Studio Podcast. This week's segments included:   Off the Needles On the Needles Brainstorming From the Armchair KAL News Events Contest, News & Notes Life in Focus On a Happy Note     Thank you to this episode's sponsors Colorful Eclectic, Dragonfly Fibers, KnitCircus Yarns   Come chat about this episode in the Ravelry group! Off the Needles   Amma Granny Square Top Pattern: Amma Granny Square Top by Maria Valles Hook: C 2.75 mm Yarn: Aunt Lydia’s Crochet Thread Classic 10 in a creamy vanilla color Finished last year and brought it to Key West. The bottom trim got stuck on something in my suitcase and unraveled so I ripped back and finished it again. Peregrine Falcon Pattern in Spirit Animals Book by  by Jessica Boyer put out by Leisure Arts. $10 ebook copy from their website. Yarn: Knit Picks Brava and Cascade 220 Superwash Hook: C This is made in many pieces. Finishing instructions aren't great but the FO is cute!     New Stash Dash Total: 4,429.9 meters On the Needles   Reese's Christmas Stocking Pattern: Christmas Stockings to Knit and Crochet from Family Circle Magazine Yarn: Knit Picks Wool of the Andes in Red, Everglade Heather and White Hook: F (3.75 mm)   Black/Gray Patons Socks Yarn: Patons Kroy Stripes in the Eclipse Stripes Colorway Needles: US 1.5 (2.5 mm) Pattern: OMG Heel by Megan Williams First sock is done.   Cozy Christmas Socks Yarn: Cozy Knitter Bliss Sock in the Joyful colorway Needles: US 1.5 (2.5 mm) Pattern: OMG Heel by Megan Williams   Holly Jolly Christmas Socks Yarn: Dancing Dog Dyeworks Twist Sock in the Holly Jolly colorway Needles: US 1.5 (2.5 mm) Pattern: OMG Heel by Megan Williams   Garret's 2 Part Socks Yarn: White Birch Fiber Arts Merino/Nylon in the Nothing Says Screw You Like a Rainbow Needles: US 1.5 (2.5 mm) Pattern: OMG Heel by Megan Williams   Jujuy  Pattern: Jujuy by Joji Locatelli Needles:US 5 (3.75) Yarn: O Wool O-Wash Fingering   Brainstorming Will wants another crochet monster like Rock n Rolla (aka Binky the Bubbly Monster- free pattern) Sunday Slippers; super cute free pattern for Super Bulk Slippers Mimic - boxy short sleeved pullover Tiles for Miles free crochet Baby Blanket pattern From the Armchair Finished reading Truly, Madly, Guilty by Liane Moriarty Crafty Blog post re: 7 Smart Hacks to Crochet Perfectly Straight Edges KAL News   12 Months to Christmas KAL Click here to find about more about this KAL. Check out: Chat Thread & FO Thread  The 12 Months to Christmas KAL is a craft-a-long that helps you prepare for the busy winter holiday season. Complete gift projects each month (or just in the months that you choose) so you don’t have to scramble in December. Find some cool new gift ideas, cheer each other on, and we’ll provide some motivation in the form of the potential to win prizes!         WIP’ing 2017 in the Butt Declare a WIP from the first quarter of 2017 or earlier within the first 5 days of the month, posting a photo of it in the thread. Finish the project by the end of the month, update your post with your FO photo and you'll be eligible to win a Ravelry downloadable pattern of your choosing up to $8.     Everything you need to know about the Splash Pad Party can be found here. Check out the Exclusive Items from our Pro Shop Prize Thread Questions Thread     Key Details Mentioned in this Episode Use coupon code AUGUST at periwinklesheep.com From Aug 1-15 to get 15% off your order. Finish your projects by 7/31- but don't forget you have until 8/5 to post the details in the Summer Celebration Thread.   Be sure to check out our Pro Shop Sponsors   Atelier de Soyun Blueberry Chick Yarn Colorful Eclectic Designs of Acadia Dragonfly Fibers Fibernymph Dye Works Infinite Twist Jennifer Lassonde Designs Knit Style Yarns Knitcircus Yarns Knitters Brewing Company Knitty kitty Bags One Geek to Craft Them All Pearl and Plum Plum Deluxe Tea Prairie Bag Works Skeindalous Yarns Sunsoaked yarns The Periwinkle Sheep Wooly Wonka Fibers The Pigskin Party will start up at the end of August! Interested in sponsoring, get the details and first chance at Pro Shop spots by signing up for my email newsletter and clicking the box to say you're interested in Sponsorship Opportunities. Events Fiber Revival: Saturday August 12 from 9a-4p at the Spencer Peirce Little Farm Newbury, MA Adirondack Wool and Arts Festival: September 23 & 24, 2017 VT Sheep and Wool: September 30 & October 1, 2017 Needles Up : Friday October 20 from 3-6p  conference center of the Delamater Inn, 25 Garden St Rhinebeck NY 12572- Legacy Fiber Artz, Andre Sue Knits, Sucre Sucre Minatures (Chelsea), Knit Cahoots (Cori and Megan), Fat Squirrel Speaks (AmyBeth) Indie Untangled:  Friday, Oct. 20, 2017, from 5 p.m. to 8 p.m.  The Best Western Plus, 503 Washington Ave., Kingston, N.Y. NY Sheep and Wool: October 19-22 at the Dutchess County Fairgrounds in Rhinebeck, NY Contest, News & Notes Thank you to Knitters Pride for allowing me to giveaway a set of their Knitter's Pride- Knit Blockers to one lucky winner. Tune in to see if you won!   Forgot to tell you my other favorite Knitters Pride Product: Nova Platina (I prefer fixed circulars)   Life in Focus Happiness Project 2017- July= Focus on Family Played a board game called Spontuneous with my cousins, aunt and uncle. I'm not usually huge into board games but this was fun and I'm glad I chose to say yes! We went to a movie night at local shopping center. I love the new Beauty and the Beast. Kids had a blast (Garret spent half the night talking about hand knit socks and coming up with his 2-part sock idea) I made it a point to go up to Camp to see my cousin for my great uncle's memorial service. So great to spend quality time with my cousin who lives in Florida. On a Happy Note Kayaking Christi78 reached out to say: " Really enjoyed this episode. Just thought I'd toss out that LL Bean offers great trips, including my favorite - a full moon paddle around Casco Bay. When we went we saw seals and it was a magical date night." Dan and I did about 8 miles of kayaking in NH last week. I love it so much!  I've been experimenting with getting at least 70g of protein per day to see if it will help me build muscle and potentially lose a pound or two. Some resources I mentioned My Fitness Pal (app and website Garden of Life Raw Chocolate Protein Powder, 365 Grass Fed Whey Vanilla Protein Powder, Garden of Life Raw Unflavored Protein Protein Pancakes- 2 scoops vanilla protein powder, 1 whole egg, 2 tbsp PB2. Syrup- 2 tbsp PB2 plus some water.  -----------   Thank you for tuning in!   Contact Information: Ravelry: BostonJen & Down Cellar Studio Podcast Ravelry Group Twitter: Instagram & Periscope: BostonJen1 Facebook: https://www.facebook.com/downcellarstudio Sign up for my email newsletter to get the latest on everything happening in the Down Cellar Studio!

Callie Blount grew up in a Southern home and was taught that hospitality is a fantastic way to show love. Carrying those traditions forward, Callie talks in this interview about how to be hospitable while still maintaining time for self care, yet not being afraid to be vulnerable and allow people into her home. Callie teaches, "People aren't going to remember what your house looked like. They're going to remember how you made them feel." Callie loves beauty, people and creating, which she uses in her career as a food stylist. She blogs at Luv-Cooks.com. She lives in Nashville with her husband Jake and their cute dog Bigsby.  Nuggets of Wisdom from Callie: "Life is either a grand adventure or nothing else." ~Helen Keller "I was raised in a very southern household with a very southern mama who I absolutely adore. I grew up in this culture of - whether it was a wedding or a funeral or a baby shower - her motto was 'Well, ya gotta eat!' so you might as well be eating at her house. This culture of beautiful tables and beautiful spreads and this enjoyment of food and of people.... There's something about this love of food, love of people, and love of beauty that resonates in my spirit and brings me such fulfillment." "My mom modeled for me this culture of hospitality. For her it was her way to love us well." "The best way to love somebody is to cook for them." "Hospitality is more about the people who are sitting in your living room than it is about you looking fancy or like the coolest hostess in the world. It's about loving them well and making them feel special." "It's about having a good time and celebrating life with the people around you. It's really more important the way people FEEL when they're in your home than the way your home appears to them." "Today is the day that I have. Today is my grand adventure. I'm not promised tomorrow. Today is my chance to love people, to be kind to them, to have a good time with whatever situation I'm in and to let my intention be TODAY." "At the end of the day, land on the side of relationship." "People who can celebrate food are the best people!" Some of Callie's Favorite Things: Personal habit: "I pray all the time. I try to still myself and maintain a place of peace in my spirit." Easy meal: Roasted Veggie and Quinoa Bowl with Creamy Asian Dressing (See below in the Resources for the recipe) Favorite Kitchen Gadget: "Buying a Vitamix Blender has changed our world!" (See below in the Resources for Callie's Chocoholic Smoothie recipe) Callie's Favorite Book: Bread and Wine by Shauna Niequist Best advice received: "The enemy of good is perfect." Callie's Happiness Formula: "Encourage, Feed, and Inspire People." A Challenge from Callie: "Go out there and practice hospitality. Choose to land on the side of community!" Resources Luv-Cooks.com Turkey Pumpkin Chili Bread and Wine by Shauna Niequist Callie's Pump-Me-Up Chocoholic Smoothie   1 cup (8 ounces) chocolate coconut water 1 scoop chocolate protein powder 1 tablespoon cocoa powder (if you want it SUPER chocolatey) 1-2 tablespoons powdered peanut butter (I like PB2) 1/2 banana 5 ice cubes   Pour all ingredients into a Vitamix (or other blender of choice). Blend on low, slowly increasing speed to high to thoroughly mix ingredients and create a foamy texture. Enjoy!! Roasted Veggie and Quinoa Bowl with Creamy Asian Dressing Serves 2 for a meal or 4 for a hearty side For the vegetables: 1 sweet potato, diced 1/2 pound okra, sliced into thin circles OR 3 carrots, sliced on the diagonal 1/2 head broccoli, sliced into florets 2 tablespoons olive oil 1 teaspoon cumin 1/2 teaspoon chili powder 1/2 teaspoon salt (or to taste) 1/4 teaspoon freshly ground pepper For the quinoa: 1 cup quinoa 2 cups vegetable or chicken broth For the Asian dressing sauce: 3 tablespoons Sun Butter (or peanut or almond butter) 2 teaspoons soy sauce (or more to taste) 1 teaspoon honey 1/2 teaspoon lime juice 1/4 teaspoon red pepper flakes Green onions, sliced (for topping) Toasted sesame seeds (for topping) What You Will Do: 1. Preheat oven to 425 degrees, and line two large baking pans with aluminum foil sprayed lightly with cooking spray. 2. In a large bowl, toss together vegetables, cumin, chili powder, salt and pepper until all the vegetables are coated with oil and spices. 3. Place vegetables on cooking sheets, spreading evenly. 4. Bake for 25-30 minutes, stirring vegetables halfway through cooking, until yummy and a bit crispy on the edges. 5. While the vegetables are cooking, bring broth and quinoa to a boil. Cover; let simmer for 15 minutes, or until all water is absorbed and the whites of the quinoa are showing through. 6. Stir together Sun Butter (or nut butter of choice), soy sauce, honey, lime juice and red pepper flakes. 7. To assemble; layer quinoa and vegetables in bowls. Top with Asian dressing, green onions, and sesame seeds. Subscribe to Vibrant Happy Women:  

Ashley Buzzy McHugh drops by for the 3rd time to discuss the greatest slow jamz of all time, a very interesting Instagram account and try PB2 powdered peanut butter/chocolate.

Life, goals, expectations, abs, tortilla chips, a bronze-skinned, SoCal-dwelling alter ego… We want it all. In this episode we try to find a little bit of balance for all of those things, starting with a wrap-up of our WAG experiences and some discussion about what our lives are going to look like moving forward. Spoiler, Joy’s life is still going to involve a LOT of PB2. We answer a few listener questions, recap our super fun photo shoot, and lament about how great it would be to have a full-time stylist to do our hair in the morning. Because really. #SOFAMOUS Girls Gone WOD Podcast is sponsored by QALO http://qalo.com        

Runners of the Week and featured guests, Tom Kreider and daughter Kristen, give pre- and post-race stories/reviews of their recent Disney races in January 2016. Serena Marie takes off her registered dietitian hat and reviews Sparkle Skirts, alongside dear TRLS friend Tracy Slayton. Kari also chats with Serena and shares her fun weekend meet up experience. Featured Guests and Runners of the Week: Tom and Kristen Kreider Tom Kreider, top individual donor to Kari and Serena's Action for Healthy Kids campaign to run the Chicago and NYC Marathons, joins his daughter Kristen to talk about their recent pre- and post-Disney race experiences. The Lay of the Land In 11 days, they completed seven races (71 miles total) around Disney World, a Disney Cruise Line, and Disneyland—all nonstop—and received a whopping 13 medals! In Disney World, they attended January marathon weekend and ran the Dopey Challenge, which consists of the following: Thursday: 5K Friday: 10K Saturday: Half marathon (~25,000 runners) Sunday: Full marathon Most run to experience the atmosphere of the parks, and Tom says it's a “really nice four-day party.” Tom and Kristen ran the half two years ago, and last year they ran the Dopey Challenge. In the marathon, you run through all four parks that include some special challenges: You can choose to ride the Expedition Everest roller coaster (around Mile 12.5) in the Animal Kingdom. When you run through Epcot and the World Showcase, you can stop at the various kiosks and pick up beverages (around Mile 25). The marathon starts around 5:30 a.m. (with corrals from A–P and waves that start every five minutes). The 16-minute-per-mile maximum pace allows for stops to take pictures with characters or ride Everest. There are water stops about every mile and a half, and at every single water stop there are lines of Porta-Potties. Cruise Experience On Monday morning, they went to Disney Cruise Lines at Cocoa Beach/Port Canaveral for a four-day cruise. On Wednesday, they stopped at Castaway Cay for a 5K race (~800 people registered), which is a special race for those who ran Marathon Weekend. Participants receive a 5K race medal, along with a special challenge medal. Disneyland Friday of that week, they leave the cruise to fly over to Disneyland for the Rebel Challenge. The Star Wars: Light Side—which is a 10K on Saturday and a half marathon on Sunday. Once they complete the challenge, they receive the Coast to Coast medal as well. Part 1: Before the Race Before the race, Kristen was most looking forward to the cruise itself and also the half marathon, because Tom and Kristen ran their first half marathon together. Kristen's biggest concern was transportation due to closed roads while she cheered Tom on. Tom's concern was not getting on the cruise ship in time for a good massage appointment (because that's a MUST after so much racing). Tom talks about dialing back his pace which led him to a better mindset and feeling better physically. Part 2: After the Race Tom and Kristen sum up their experience in a couple words: work and logistics (traveling for 12 days straight) They loved the races, meeting up with people, and the following: The race expos The race start. which is highly organized, great announcers (like Rudy Novotney and Creigh Kelley), there's a DJ/music, they show videos, and so on. For example, at the Star Wars half they had Stormtroopers, and the race announcers were in costume! The water stops were well stocked, along the course they have characters, high school marching bands, and the like. Best magical moment: Kristen and Tom at the end of the Castaway Cay 5K (gentle was their mantra for that race). The pain after running the Dopey Challenge wasn't as bad as after the entire trip for Tom. They traveled with about 80 people who were part of the Mickey Milers that focus on runDisney races. Only about 200 people did all seven races. For the Dopey Challenge, the bus transportation from the resorts started at 3 a.m. They got up around 3:30 a.m. and were on the bus by 4 a.m. They walked about half a mile to the start corrals, and they got to their corral around 5 a.m. The race started at 5:30 a.m., and every corral start time was separated by two to three minutes. They started around 20 minutes The half marathon course ran through the Magic Kingdom and finished in Epcot. The full marathon ran through the Magic Kingdom, Animal Kingdom, ESPN Wide World of Sports (around Miles 18 and 20), Hollywood Studios, and Epcot. Jeff Galloway was on the cruise ship and talked to Tom and Kristen about TRLS. runDisney had an official event on the ship where Jeff was presenting. When the Mickey Milers had an awards ceremony (with a special Mickey Milers medal), Jeff put medals on their necks. Top tips/inside scoop from Tom: Running all four races in Orlando is a logistical planning exercise. Getting up at 3 a.m. four mornings in a row and then performing on the race course is tough, and you don't get a lot of time in the parks. Disney challenges will sell out within minutes, so get on the e-mail list. Registration always happens on a Tuesday at noon, so be prepared and log in with your Active.com account all ready to go! Registration is typically nine months before the race. Races are pricey, but they're first class (Dopey was $695; Rebel Challenge was ~$350; Castaway Cay challenge medal was $60; $1,600–1,800 for the cruise room). Tom used a company called Mouse Fan Travel to plan the trip. Top takeaways from Kristen: Supporting a race is almost more annoying than running it, because it was stressful (transportation, logistics with timing). Don't forget your nutrition! Oh, and get the pot roast mac and cheese from The Friar's Nook—it'll change your life! The registration for the Wine & Dine Half Marathon Weekend is March 15.   Sparkle Skirts Review Serena Marie, RD, and the #1 fan of TRLS, Tracy Slayton, review Sparkle Skirts! At the Jeff Galloway Race Weekend, Tracy picked out a Sparkle Skirt for Serena. Serena's take: She is obsessed! She isn't an exclusive skirt wearer, but she owns some running skirts, and this brand (and particularly the Sparkle Skirt Swing model) by far knocked it out of the park. The design is adorable with a little flare. The spandex shorts didn't ride up, and they were the perfect length. Tracy: At the JG 13.1 race, she got two of them, and she now owns six Sparkle Skirts. She loves the coverage, a zippered pocket in the waistband, and the thicker waistband. You can wear it either forward or backward (with the pocket in the front or back respectively). Tracy has the Swing model that has a little flounce and a bit more coverage. The Sparkle Skirt Facebook fans are so loyal and excited about the brand. Kari met Leah and Tom, the owners, in Atlanta, and she loves their mentality and the fact that the skirts come in a variety of sizes. The shorts don't ride up, she loves the larger pockets, that it's American made, and that you can put them over capris or running tights in colder weather. Kari has the Slim model in blac Since you have so much space in the pockets, you could bring along some real-food fuel like Serena Marie RD's RaceRice. Ingredients 1 cup cooked rice (prepared with salt) 3 Tablespoons egg white 2 Tablespoons powdered peanut butter (PB2) 1" ginger root minced (optional- will make it VERY gingery tasting)Directions Form 12 small balls (a little larger than quarters). Flatten slightly so they're disc shaped. 2. Spray a pan with coconut oil over medium high heat 3. Cook for about a minute per side. They shouldn't fall apart when flipped. 4. Carry with you in a plastic baggy & pop 3 every 45 minutes! Per 3 race rice cakes (counts as 1 starchy grain) Calories 66 Carbs 13gm Protein 3gm Fat 1gm Kari and Serena Updates and Misc. Kari admires Serena's “guns” (from lifting), and Serena updates Kari on her HIIT workouts. Kari talks about her Harrisburg, PA trip, the Big Kahuna's swim meat, and her meet up with Jeff Paladina at Fleet Feet Sports (thanks to Fred and Shelby Joslyn!). Kari shares all about her injury—her heel was hurting, and her hip and hurt still hurt. She went to a physical therapist, and her whole right leg went numb all of a sudden. There might be an MRI in her future. The feedback that Kari got during her PA trip include the following: the show is positive, optimistic, and Serena is like Kari's younger sister. Jeff Paladina paired Kari up with a walker during the meet up. Question for Serena: What are the benefits of oregano oil? Sneak peek: Kari chats with Dr. Ratey on an upcoming habit: They talk about what's going on with him, that he feels we're at a tipping point to gut health, brain health, to meditation, to being outside, and so on. They also talked about the Shake Yo' Sugar Habit challenge. In an upcoming episode, Kari interviews eight runners from the Harrisburg running club (the River Runners group), and she interviewed the founders of the group, along with an interview with Jeff Paladina. Kari gives an update on her Shake Yo' Sugar Habit challenge experience. In the challenge, Serena has a real-food approach, but she also includes some of the standard American diet nutritional sciences approach to translate into real food. She examines the fruits (melons, berries, citrus fruits) that you can have larger portions of versus fruits like mangoes, apples, and bananas, because those foods are higher in water and fiber content and lower in fructose content. Don't forget to join the TRLS Facebook group! Two days after Luke Puskedra took fourth place in the Olympic Marathon Trials, his seven-month-old daughter was diagnosed with cancer. Check out the Go Fund Me campaign. Jabra Don't forget that Jabra, a TRLS show sponsor, is giving away a pair of Pulse earbuds this month, so head over to Jabra.com/TRL and sign up for the TRLS e-mail list at therunninglifestyle.com/join to enter to win. March's winner will also receive an exciting thirty-­minute exclusive Skype call with Kari. She loves the Pulse model because it's wireless, has superior sound quality, and includes in-­ear heart rate monitoring. The winner of the February drawing is Erica Barton. Congratulations, Erica! Next week, Kari and team talk about February's book of the month, Better Than Before: What I Learned About Making and Breaking Habits—to Sleep More, Quit Sugar, Procrastinate Less, and Generally Build a Happier Life by Gretchen Rubin. Listeners Tracy Slayton and Foti Panagakos, along with Kari and Serena, will talk about their tendencies so that you can better understand the concept. Contact: Tom Kreider: Website: TomsMagicalTravel.com Twitter: @tomsmagical Facebook: /TomsMAgicalTravel Intagram: @tomsmagicaltravel Serena Marie, RD: Website: www.SerenaMarieRD.com Facebook: /SerenaMarieRD Twitter: @SerenaMarieRD Instagram: SerenaMarieRD Kari Gormley: Facebook: The Running Lifestyle Show Twitter: @KariGormley Instagram: @KariGormley

This week Mr. David Palan and I do a little catch up and then complete the corcle when we talk with Arley Kemmerer from PB2 and the 2014 US CX Worlds team.  Then I talk with Brian Segal and Joe Czerwonka about SSCXWC 2014!!!!!! in Louisville.

In which we discuss: The Oscars, The Jordys, Guilty Pleasures or lack thereof, PB2, Chances Are, and Rich's possible repressions.

Elena Becker-Barroso discusses highlights from the September issue, including the potential of PB2 to slow the development of amyloid beta in patients with Alzheimer's, and how telemedicine could improve stroke treatment.

Das σ54-abhängige Regulatorprotein FhlA aktiviert die Transkription der für die Bildung eines funktionellen Formiat-Hydrogen-Lyase-Komplexes nötigen Gene. Hierfür weist es eine Reihe von Aktivitäten auf, nämlich ATP-Hydrolyse, Interaktion mit Eσ54 und Stimulierung der Transkription. Die Aktivität von FhlA wird durch Bindung von Formiat und von spezifischen DNA-Sequenzen (UAS) stimuliert und durch HycA negativ beeinflußt. Sequenzähnlichkeiten von FhlA zu anderen Transkriptionsaktivatoren lassen auf einen Aufbau aus drei Domänen schließen. Die in der vorliegenden Arbeit erfolgte Struktur- Funktions-Analyse lieferte wichtige Ergebnisse über die Domänenstruktur und den Wirkungsmechanismus von FhlA. In vivo- und in vitro-Analysen der C-terminalen Hälfte von FhlA (FhlA-C, Aminosäuren 379 bis 693 von FhlA), welche die Domänen B, C und D von FhlA umfaßt, zeigten, daß dieser Teil von FhlA sämtliche für die Transkriptionsaktivierung und ATP-Hydrolyse benötigten Bereiche enthält. Beide Aktivitäten von FhlA-C sind konstitutiv, bedürfen also nicht mehr der Aktivierung durch Formiat-Bindung. Durch die Bindung von DNA konnte die Aktivität von FhlA-C jedoch gesteigert werden, wobei bei spezifischer DNA ein stärkerer Effekt als bei unspezifischer zu beobachten war. Aus den Ergebnissen wurde ein Modell abgeleitet, in welchem die N-terminale Domäne von FhlA im nicht-induzierten Zustand einen hemmenden Einfluß auf die Aktivität des restlichen Proteins hat. Formiat-Bindung an die N-terminale Domäne hebt diese Hemmung auf und bewirkt eine Steigerung der Aktivität von FhlA durch Erhöhung der Affinität für ATP. Auch die HycA-Suszeptibilität konnte der N-terminalen Domäne zugeordnet werden. Darüberhinaus besitzt die N-terminale Domäne eine strukturelle Funktion, da sie für die Oligomerisierung von FhlA verantwortlich ist. Es konnte gezeigt werden, daß die Bindung von ATP an FhlA eine Änderung der Konformation oder des Oligomerisierungszustandes des Proteins zur Folge hat. Eine Studie zur Verbreitung des FhlA-Regulationssystems ergab, daß in mehreren Spezies der Familie Enterobacteriaceae sowohl ein zu FhlA orthologes Protein als auch Homologe zu hyc- oder hyp-Genen existieren. Die Sequenz von fhlA aus S. typhimurium, E. aerogenes und K. oxytoca wurde bestimmt. Sie zeigt über die gesamte Länge große Ähnlichkeit zu FhlA von E. coli, wobei der Grad der Identität der Gene und Proteine den phylogenetischen Verwandtschaftsverhältnissen entspricht. Die FhlA-Orthologe aus E. aerogenes und K. oxytoca können FhlA aus E. coli funktionell ersetzen und zeigen auch in ihrer Aktivität hinsichtlich der Stimulierbarkeit durch Formiat und Anaerobiose große Übereinstimmung. Desweiteren beeinflußt auch HycA von E. coli die Aktivität der orthologen Proteine, was wiederum die nahe Verwandtschaft der Regulationssysteme zeigt. Im Hauptteil dieser Arbeit konnte der Beweis erbracht werden, daß das HydH/G-Zwei- Komponenten-System die Expression von zraP aktiviert, einem stromaufwärts von hydH gelegenen, in divergierender Richtung orientierten Gen. Für gereinigtes HydG wurde durch Gelretardationsexperimente und DNase I Footprinting-Analyse eine Bindestelle identifiziert, die im intergenen Bereich zwischen hydHG und zraP liegt. Diese 55 bp lange Region umfaßt zwei jeweils 17 bp lange Bereiche mit der Sequenz GAGTAAAAATGACTCGC, die als inverted repeat angeordnet sind. Diese Bindestelle wirkt als UAS in beide Richtungen. Als auslösender Stimulus für die Expressionsaktivierung von zraP durch HydH/G konnte eine Zn2+-Konzentration im Medium von mehr als 0,5 mM identifiziert werden. Pb2+ war zu einem gewissen Grad in der Lage, Zn2+ in der Funktion als Induktor zu ersetzen, jedoch erfolgte keine Aktivierung durch Ni2+, Co2+, Mn2+, Fe2+, Mg2+, Cu2+, Cd2+ oder Hg2+. Gleichzeitig ist HydH/G einer positiven Autoregulation unterworfen, die durch die gleichen Metalle induziert wird. Sowohl für die durch HydH/G induzierte Expression von zraP als auch von hydHG konnte eine Abhängigkeit von σ54 gezeigt werden. Der Einfluß von HydH/G auf die Regulation der Gene für die Hydrogenase 3 tritt entgegen früherer Postulate nur bei Überproduktion des Regulators auf und ist auf "cross-talk" zurückzuführen. Zweidimensionale Gelelektrophorese erbrachte Hinweise auf weitere durch HydG in ihrer zellulären Konzentration beeinflußte Proteine. Obwohl zraP im Zusammenhang mit Zink- Toleranz identifiziert worden war, zeigten die Ergebnisse keinen Einfluß von HydH/G oder ZraP auf die Zink-Toleranz der Zellen.