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The final Medicine and the Machine podcast guest, physician and author Gavin Francis, shares his approach to keeping his occupation rewarding and satisfying. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Gavin Francis, MBChB (Hons), BSc (Hons), Department of Primary Care, Edinburgh University; General Practitioner, Department of Primary Care, Community Clinic, Edinburgh Free For All. https://www.gavinfrancis.com/books/free-for-all-why-the-nhs-is-worth-saving/ Recovery: The Lost Art of Convalescence. https://www.gavinfrancis.com/books/recovery/ Adventures in Human Being. https://www.gavinfrancis.com/books/adventures-in-human-being/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
He's alive thanks to a repurposed drug. Now his dream is to find cures for millions of people from among drugs we already have. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape David Fajgenbaum, MD, MBA, MSc, Associate Professor, Department of Medicine; Director, Center for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Philadelphia, Pennsylvania Chasing My Cure. https://chasingmycure.com/ His Doctors Were Stumped. Then He Took Over. - The New York Times https://www.nytimes.com/2017/02/04/business/his-doctors-were-stumped-then-he-took-over.html Every Cure. https://everycure.org/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Dr Eric Topol discusses the present and future of AI in medicine with historian and futurist Dr Adam Rodman. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Adam Rodman, MD, MPH, Instructor of Medicine, Department of Internal Medicine, Harvard Medical School; Co-director, iMED Initiative, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts SHORT CUTS: MEDICINE, Navigate Your Way Through Big Ideas, Adam Rodman, MD, MPH; ISBN: 9781785789946. https://iconbooks.com/ib-title/short-cuts-medicine/ Bedside Rounds podcast. http://bedside-rounds.org/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Dr. Paddy Barrett is a Dublin-based cardiologist who is a well-known thought leader on all things related to heart health. He's done work with the meditation app, HeadSpace; he's partnered with NASA on medical devices in zero gravity settings, and he's spent time doing research and training at Columbia University Medical Center, The Scripps Translational Science Institute in California among other. In short, he's done a lot. He also happens to be a great content producer writing regularly on his weekly Substack and on Twitter and LinkedIn. See links below. In the following conversation, Dr. Barrett and Greg talk about all things cardiovascular health and more specifically how to avoid a heart attack. Episode Segments: (06:06) -- What a heart attack is – and differentiating between risk factors, disease & events (12:42) -- Understanding your cardio risk factors (17:48) -- LDL cholesterol, apoB, and the role of insulin resistance (22:18) -- What LDL-c and apoB targets to aim for (30:24) -- Why focusing on your lipid panel alone is not enough (34:32) -- Why you need to know your LP(a) level especially if your family history includes early heart attacks (40:58) -- The upsides and downsides of CT calcium scans, CT angiograms and stress echo tests (55:34) -- A multi-faceted approach to lowering your risk of coronary artery disease (58:05) -- Why being “average” is not a good result Make sure to follow Dr. Barrett on Twitter, LinkedIn and Substack: https://twitter.com/Paddy_Barrett https://www.linkedin.com/in/paddybarrett/ https://paddybarrett.substack.com/ Don't forget to follow Greg on Twitter @gregorycampion and subscribe to his bi-weekly newsletter: https://gregcampion.substack.com Link to (very) raw transcript of this conversation: https://share.descript.com/view/TokpYioiMbM If you enjoyed this episode, please consider rating and reviewing Intentional Wisdom wherever you get your podcasts. --- Send in a voice message: https://podcasters.spotify.com/pod/show/intentionalwisdom/message Support this podcast: https://podcasters.spotify.com/pod/show/intentionalwisdom/support
A new book reveals how chance can change the course of a person's health, life, and death. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California The Covenant of Water, Abraham Verghese, MD; https://www.abrahamverghese.org/books/ Anupam B. Jena, MD, PhD, Joseph P. Newhouse Professor, Department of Health Care Policy, Harvard Medical School; Physician, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts Random Acts of Medicine. Anupam B. Jena and Christopher Worsham. Penguin Random House. https://www.penguinrandomhouse.com/books/708150/random-acts-of-medicine-by-anupam-b-jena-md-phd-and-christopher-worsham-md/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
The medical and dental students who kept polio patients alive by hand-ventilating them around the clock are among the cast of characters in this incredible story. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Hannah Wunsch, MD, MSc, Professor of Anesthesiology and Critical Care Medicine, Department of Anesthesiology, University of Toronto; Staff Physician, Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada The Autumn Ghost, Hannah Wunsch, MD; https://greystonebooks.com/products/the-autumn-ghost Why we can thank a polio emergency for the birth of intensive care; Nature 618, 234-235 (2023), Eric Topol; https://doi.org/10.1038/d41586-023-01830-3 You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
The gig was up, but when he finally got COVID, it was pretty far down on his ER problem list. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California The Covenant of Water, Abraham Verghese, MD; https://www.abrahamverghese.org/books/ Robert M. Wachter, MD, Professor and Chair, Department of Medicine, University of California, San Francisco https://twitter.com/Bob_Wachter You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Information pollution is just the beginning. We're in for an uncomfortable ride. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Isaac S. Kohane, MD, PhD, Chair and Professor, Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Dr Eric Topol and Dr Robert Harrington interview Dr Abraham Verghese about his fiction writing methods and Oprah's enthusiasm for his latest novel. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California The Covenant of Water, Abraham Verghese, MD; https://www.abrahamverghese.org/books/ Robert A. Harrington, MD, Arthur L. Bloomfield Professor; Chair, Department of Medicine, Stanford University; Chair, Department of Medicine, Stanford Medical Center, Stanford, California Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic For questions or feedback, please email: news@medscape.net
Dr Helen Ouyang on why she writes so much about the hospital-at-home movement: It's the future, one way or another. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Helen Ouyang, MD, MPH, Associate Professor, Department of Emergency Medicine, Columbia University Vagelos College of Physicians and Surgeons; Attending Physician, Department of Emergency Medicine, Columbia University Irving Medical Center, New York, NY Your Next Hospital Bed Might Be at Home, The New York Times Magazine. https://www.nytimes.com/2023/01/26/magazine/hospital-at-home.html Hashtag Prescription, Harper's Magazine. https://harpers.org/archive/2016/06/hashtag-prescription/ Acute Hospital Care at Home Individual Waiver Only (not a blanket waiver), CMS.gov. https://qualitynet.cms.gov/acute-hospital-care-at-home You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Should our nation's academic institutions rein in faculty who amplify conspiracy theories and spread potentially harmful falsehoods? This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Robert A. Harrington, MD, Arthur L. Bloomfield Professor; Chair, Department of Medicine, Stanford University; Chair, Department of Medicine, Stanford Medical Center, Stanford, California You may also like: Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic For questions or feedback, please email: news@medscape.net
Dr. Ravi Komatireddy, MD, MCTI is a board-certified internal medicine physician who trained at Dartmouth Hitchcock Medical Center and the University of California San Diego. Additionally, he was the first wireless digital health scholar at the Scripps Translational Science Institute, where he earned a masters in clinical translational investigation. Previously, he co-founded and served as Chief Medical Officer of two funded digital health startups: Lumiata Inc., a big data, AI healthcare company, and Reflexion Health Inc., a digital medicine, tele-health physical therapy solution using motion tracking cameras in the home. His interests include aerospace medicine and developing world digital health. He received the first grant from the NASA flight opportunities program to advance research in digital health and human spaceflight and continues to work with NASA on a COVID-19 Taskforce; he helped introduce a digital health model to medical startups operating in Nairobi, Kenya health tech ecosystem. Links:Ravi on LinkedIn and Twitter
ChatGPT and large language models offer physicians the chance to do what they went to medical school for: connect with patients and help them regain their health. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Aaron B. Neinstein, MD, Associate Professor, Department of Medicine, University of California, San Francisco; Vice President, Digital Health, UCSF Health, San Francisco, California Our AI Future is Better Than You Think: https://www.nature.com/articles/s41591-022-02021-9 Tidepool: https://www.tidepool.org/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Eric Topol and Abraham Verghese chat with the UK's professor Hannah Fry about taking risks and asking the right questions. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Hannah Fry, MSc, PhD, Professor, Mathematics of Cities, University College London, London, United Kingdom Hello World: How to be Human in the Age of the Machine https://hannahfry.co.uk/book/hello-world/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Two-way masking is pretty effective, but it's not sustainable. Environmental engineer and viral transmission expert Dr Linsey Marr reveals how we can fight COVID by tackling our contaminated air. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Linsey Marr, PhD, Charles P. Lunsford Professor, Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia Study shows cloth face coverings help protect both wearers and those nearby https://vtx.vt.edu/articles/2020/11/eng-marrmasks-1123.html You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Dr Trish Greenhalgh explains how we miss the boat when we discount real-world evidence in favor of randomized trial evidence. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Trish Greenhalgh, OBE, MD, Professor of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom Orthodoxy, illusio, and playing the scientific game: a Bourdieusian analysis of infection control science in the COVID-19 pandemic [version 3; peer review: 2 approved]. Wellcome Open Res 2021, 6:126 https://doi.org/10.12688/wellcomeopenres.16855.3 Ten scientific reasons in support of airborne transmission of SARS-CoV-2. The Lancet, Vol 397; May 2021 https://doi.org/10.1016/S0140-6736(21)00869-2 Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent. BMJ Evidence-Based Medicine October 2022; volume 27; number 5 http://doi.org/10.1136/bmjebm-2022-111952 Long covid—an update for primary care. BMJ 2022;378:e072117 http://doi.org/10.1136/bmj-2022-072117 You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Stephen Thrasher discusses his new book, The Viral Underclass: The Human Toll When Inequality and Disease Collide. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Steven Thrasher, PhD, Assistant Professor, Daniel H. Renberg Chair, Department of Journalism, Northwestern University Medill School of Journalism, Evanston, Illinois The Viral Underclass https://us.macmillan.com/books/9781250796639/theviralunderclass You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Virologist Jeremy Kamil shares his relatively upbeat perspective on the viral threats we face today. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Jeremy P. Kamil, PhD, Associate Professor, Department of Microbiology and Immunology, Louisiana State University Health, Shreveport, Louisiana You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Another COVID-19 variant is inevitable because we aren't doing anything to stop it, says UK operational researcher Christina Pagel. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Christina Pagel, PhD, Professor, University College London, London, United Kingdom You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington
An AI model accurately predicts a person's race from a chest radiograph with stunning accuracy. Here's why it matters, and how it poses research questions about bias in medicine. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Judy Gichoya, MD, Assistant Professor, Department of Radiology, Emory University, Atlanta, Georgia AI recognition of patient race in medical imaging: a modelling study: https://pubmed.ncbi.nlm.nih.gov/35568690/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Eric Topol speaks with DeepMind CEO Demis Hassabis about harnessing the potential of AI in health and medicine. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Demis Hassabis, PhD, Founder and CEO, DeepMind, London, United Kingdom https://www.deepmind.com/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Pain is central to every specialty, and we all played a part in the opioid crisis, says Dr Haider Warraich, author of The Song of Our Scars: The Untold Story of Pain. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Haider Warraich, MD, Assistant Professor, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital; Associate Director, Heart Failure Program, VA Boston Healthcare System, Boston, MA The Song of Our Scars: The Untold Story of Pain. https://www.basicbooks.com/titles/haider-warraich/the-song-of-our-scars/9781541675292/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Stanford's Benjamin Pinsky on the potential for even more transmissible and pathogenic versions of the SARS-CoV-2 virus to arise. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Benjamin Pinsky, MD, PhD, Associate Professor, Department of Medicine and Pathology, Stanford University School of Medicine; Director, Clinical Virology Laboratory; Associate Director, Clinical Pathology for COVID-19 Testing, Stanford Health Care, Stanford Children's Health, Stanford, California You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Why we should be shifting into high gear on treatments for long COVID and a pan-beta-coronavirus vaccine. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Former NIMH Director Tom Insel explains how the medical model has failed the field of psychiatry. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Tom Insel, MD, President, Mindstrong Health, Palo Alto, California Healing: OUR PATH FROM MENTAL ILLNESS TO MENTAL HEALTH By Thomas Insel, MD https://www.penguinrandomhouse.com/books/670329/healing-by-thomas-insel-md/ You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Epidemiologist-engineer Michael Mina thinks diagnostics belong in the hands of the people. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Michael Mina, MD, PhD, Chief Science Officer, eMed Digital Healthcare, Miami, FL You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Randy Olson on what science can learn from Hollywood about communicating with the masses. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Randy Olson, PhD, MFA, Independent filmmaker You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
In the latest episode of Exchanges at Goldman Sachs, Jeffrey Shaman, Director of the Climate and Health Program at Columbia University's Mailman School of Public Health, and Dr. Eric Topol, Founder and Director of the Scripps Translational Science Institute, discuss the rapid spread of the Omicron variant of SARS-CoV-2 and the potential shift to an endemic phase of the pandemic in 2022.
Two bouts with cancer and a cardiac arrest at age 35 haven't stopped this ophthalmologist-comedian from becoming a social media phenomenon for hilariously poking fun at medicine and himself. This podcast is intended for US health professionals only. Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California William E. Flanary, MD, EyeHealth NW, Portland, Oregon You may also like: Medscape's Chief Cardiology Correspondent, Dr. John M. Mandrola's, This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr. Robert A. Harrington and guests on the Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
This podcast is intended for US healthcare professionals only. Eric Topol and Abraham Verghese reflect on 2021's extraordinary podcast guests, and how we excelled in science and healthcare but were tripped up by the vagaries of human behavior. For more episodes of Medicine and the Machine https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California You may also like: Medscape's Chief Cardiology Correspondent, Dr. John M. Mandrola's, This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr. Robert A. Harrington and guests on the Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
This podcast is intended for US healthcare professionals only. Andy Slavitt believes we've made real progress, despite overselling vaccines and the public's dismay with rapidly changing science. Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Andy Slavitt, General Partner, Town Hall Ventures; Former Senior Advisor to the Biden Administration COVID Response Preventable: The Inside Story of How Leadership Failures, Politics, and Selfishness Doomed the U.S. Coronavirus Response https://us.macmillan.com/books/9781250770165/preventable You may also like: Medscape's Chief Cardiology Correspondent, Dr. John M. Mandrola's, This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr. Robert A. Harrington and guests on the Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
This podcast is intended for US healthcare professionals only. Her message to academia: If you really want diversity, equity, and inclusion in medicine, put your money where your mouth is. Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Kimberly Manning, MD, Professor of Medicine; Associate Vice Chair of Diversity, Equity, and Inclusion, Department of Medicine, Emory University School of Medicine; Attending Physician, Grady Memorial Hospital, Atlanta, Georgia Medscape's Chief Cardiology Correspondent, Dr. John M. Mandrola's, This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicinewith Dr. Robert A. Harrington and guests on the Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Talking about how being vaccinated will let school-aged kids get back to normal life is paramount. This podcast is intended for US healthcare professionals only. Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Rachel Pearson, MD, PhD, Assistant Professor, Joe R. and Teresa Lozano Long Endowed Professor of Bioethics, Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas You may also like: Medscape's Chief Cardiology Correspondent, Dr. John M. Mandrola's, This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicinewith Dr. Robert A. Harrington and guests on the Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
This podcast is intended for US healthcare professionals only. If you want her to stop talking about racial and gender disparities in healthcare, fix the system. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/viewarticle/960379 Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California Ebony Hilton, MD, Associate Professor, Department of Critical Care Anesthesia, University of Virginia, Charlottesville, VA https://graddiversity.virginia.edu/ebony-j-hilton-md You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Dr Eric Topol explores the next 20 years of progress in artificial intelligence with expert Kai-Fu Lee. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/viewarticle/958771 This podcast is intended for US healthcare professionals only. Host and Guest bylines Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Kai-Fu Lee, Computer Scientist, Beijing, China You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
At home with politicians and news anchors, CIDRAP's Michael Osterholm shares three rules of science and the media, and explains why policy and science belong together like chocolate and peanut butter. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/viewarticle/951101 Eric J. Topol, MD Director, Scripps Translational Science Institute; Professor of Genomics, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Michael T. Osterholm, PhD, MPH Director, Center for Infectious Disease Research and Policy, University of Minnesota, Minneapolis, Minnesota You may also like: Medscape's Chief Cardiology Correspondent Dr John M. Mandrola's This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr Robert A. Harrington and guests on The Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net
Featured Interview: AI and the future of health care system Guest: Dr. Eric Topol, Director, Scripps Translational Science Institute, Author of
How high-definition medicine, tailored to each of us, will revolutionise the way we manage illness. Dr Eric Topol is an eminent cardiologist, geneticist, and director at the Scripps Translational Science Institute (a test ground for pioneering medical sensors, wearables & other new tech). He’s authored two bestselling books about the future of medicine and his expertise has now hit the UK as he’s writing a review for the NHS on how staff can prepare for a more digital future; the kind in which doctors, nurses and patients could be using artificial intelligence, robotics, genomics and digital medicine. In this episode of HealthHackers, Eric explains: ~ the potential power of medical treatment that is bespoke to you, rather than one-size-fits-all approaches ~ how having a “virtual coach” in your phone or smart speaker could one day prevent heart attacks, seizures and strokes ~ the future blood test that may be able to detect cancer before it has a chance to grow ~ the app that would process your macronutrients every time you take a picture of your meal ~ why obesity is not just down to eating too much ~ how treatment for T2 diabetes is “a mess” today ~ why screening everybody for a condition is “stupid” and “wasteful” ~ how your DNA and gut microbiome assessment would influence your future medical treatment ~ the purpose of gathering biological data about each of us from the moment we are born ~ how the NHS is leading the rest of the world in incorporating new technologies ~ the reason the UK is the world leader in genomics (DNA sequencing) ~ how we’ll be doing our own blood tests using our smartphones in years to come ~ his opinion of the biggest potential barrier to implementing cutting-edge health tech more widely ~ what Eric thinks of our free-at-the-point-of-use NHS system, compared to America’s paid-for structure Get the show notes here: bit.ly/2QupeGi
Podcast guest, Elise Felicione, who is currently a Scientific Collaborator at the Scripps Translational Science Institute is playing an integral role under the direction of Dr Eric Topol on a nation-wide initiative from the NIH. The initiative is called All Of Us, a US Precision Medicine program that aims to enroll a million Americans and follow them for 10 years, during which time participants will contribute biological, environmental, and lifestyle data. One-third of participants will participate virtually (not via a research site). The cohort will mirror the projected 2040 census. Individual pharma companies are never going to create cohorts like this, so the importance of this open source frame work that drug developers can tap into will be highly beneficial in serving the patient of the future. Discussion points include: What is the All Of Us Research Program?Why does this matter to biopharmaceutical companies?How far along is the program and how to get invovled?What are your biggest challenges?How can biopharmaceutical companies get involved? For more information on the All of Us program, visit: https://allofus.nih.gov/ Elise will be speaking at DPharm on September 26th and will also have an exhibit booth to answer any questions are All of Us. For information on DPharm taking place September 25-26, 2018 in Boston. For information, please visit, www.theconferenceforum.org Producer: Valerie Bowling, Executive Director, Pharma Talk Radio and DPharm
As we have touched upon, in many of our conversations, the United States health care system desperately needs reform to harness costs, improve quality and increase access. All elements of health care, including policymakers, have a role to play in transforming our system. I think everyone can agree in theory that federal policy changes are necessary to help fix this problem…..although there is lots of disagreement about what those changes should ultimately be. Such top-down solutions alone, however, cannot fix the broken system that currently exists. The broken healthcare delivery system also needs transformation from the bottom up…..by entrepreneurs and intrapreneurs - - the type of innovators that we often talk to and introduce to our listeners. So what is one of the transformative things that healthcare innovators are focused on to transform the future? Data. Specifically, individual data. So much data. Individual biology, health history, well-being, location, spending habits, sleep habits, eating habits….. According to Fortune Magazine, the amount of data you give off every day from things like lab tests, medical imaging genetic profiles, biopsies, electrocardiograms, to name just a few—is completely overwhelming when you start to think about it. Add medical claims, prescriptions, research, clinical trials….and you end up with 750 quadrillion bytes of data every day—or some 30% of the world’s data production. These massive storehouses of information have always been around. However, until three-to-five years ago, all that data was just sitting there. Now it is being analyzed and interpreted. According to Eric Topol, director of the Scripps Translational Science Institute, “It’s the most radical change happening in health care.” On this episode we are fortunate to be joined by Dr. Rasu Shrestha, one of the world’s foremost experts that understands this and the additional radical changes and trends that are driving the healthcare future forward.
Dr. Steve Steinhubl, is Director of Digital Medicine at the Scripps Translational Science Institute and director of a team that is partnering with the All of Us Research Program, an NIH led national research effort that aims to advance individualized prevention, treatment and care for people of all backgrounds. We talk about their plan to recruit one million participants as citizen-scientists, the value of capturing real time health metrics, and how digital health tools will become more robust as mobile and sensor technologies evolve. #JoinAllofUs JoinAllofUs.org Scripps Translational Science Institute
The Tacos and Tech Podcast highlights the builders of companies, technologies, and the ecosystem of San Diego with a local flair for our lifestyle as well. Meet Ashley Van Zeeland, who came to San Diego in 2008 as a postdoc scientist at Scripps Translational Science Institute and within 10 years never left a 2.5 radius mile of La Jolla/Torrey Pines. From finishing her postdoc, getting her MBA at UCSD Rady School, being the first female-led and genomics company in startup incubator EvoNexus, and acquired by cloud-first genomics unicorn Human Longevity, she has had quite the San Diego journey. She’s now advising multiple startups as she works on her next endeavor. Ashley co-founded Cypher Genomics in 2010 with Eric Topol, Ali Torkamani, and Nik Schork while in the lab at Scripps which developed software to dramatically reduce the time required to interpret raw data produced by genome sequencing. Cypher Genomics was acquired by Human Longevity in 2015 and she became the CTO of the company in 2016. Ashley speaks to the strong need for technical talent in genomics: “We have four chambers of a beating heart in genomics. We need Bioinformaticians, Software Engineers, User Experience (UX), Dev Ops skill sets.” Favorite taco spot: Oscar’s & Galaxy Taco in Pacific Beach Favorite beer: Modern Times Fortunate Islands Favorite coffee spot: Brick & Bell or Birdrock Coffee Follow @Ashley_VanZ on Twitter to see what she’s working on next! Thanks to our sponsor Cox Business for their support of the San Diego tech community. Come out to their May 10th celebration of our tech leaders by visiting http://www.toptechexecs.com/
Hillary Theakston, Executive Director, Clearity Foundation spoke at the recent Future of Genomic Medicine conference produced by the Scripps Translational Science Institute and The Scripps Research Institute. The Clearity Foundation is a great example of precision medicine in action as the Foundation produces a Tumor Blueprint for those with ovarian cancer who enroll in their program. This tumor profile can help patients and their doctors identify appropriate clinical trials, the most likely to succeed treatment, and enhance the growing genomic database of ovarian cancer mutations and drugs most likely to be effective for each individual. @clearityfnd Clearity Foundation
Internationally recognized digital health expert, Donald Jones, MBA, Chief Digital Officer at Scripps Translational Science Institute, shares his insights on the digital clinical trial landscape and the urgent need to pair digitization with drug products for patients during his keynote address from the 2016 CMO Summit. The Chief Medical Officer Summit is designed for CMOs and R&D Leadership from small to mid-size life science companies. The 6th Annual CMO Summit will be held May 7-8, 2018, in Boston.
Paul Knoepfler PhD, Professor in the Department of Cell Biology and Human Anatomy, University of California Davis is also the author of the new book GMO Sapiens: The Life-Changing Science of Designer Babies and talks with me about what stem cells can do to help create new cancer therapies as well as grow organoids in the lab to test drugs. I heard Paul speak at the recent Future of Genomic Medicine Conference produced by the Scripps Translational Science Institute. @UCDavis #FOGM17 @ScrippsSTSI GMO Sapiens: The Life-Changing Science of Designer Babies
Ed Boyden PhD, Associate Professor, Media Lab and McGovern Institute, Massachusetts Institute of Technology is exploring how light can be used to treat neurological diseases using non-invasive devices and genetic engineering. He talks about the emerging field of neurotechnology, bringing together problem experts and solutions experts to find cures and treatments for brain diseases, and the need for more investigation of the mind/body connection. I talked with Ed at the recent Future of Genomic Medicine Conference held in La Jolla CA by the Scripps Translational Science Institute. @EdBoyden3 #FOGM17 @ScrippsSTSI Syntheticneurobiology.org
The Sages & Scientists Symposium presents a panel of experts led by Poonacha Machaiah, co-founder of Jiyo, in a discussion on how technology can improve wellness. Machaiah appears as a HumaGram, demonstratiing a new technology for participating in live events from remote locations. Other guests include James Mault, MD of Qualcomm Life, Paddy Barrett of Scripps Translational Science Institute, Paul Duffy of ARHT Media, Moira Burke of Facebook, Simon Leung of NetDragon, Sridhar Solur of Comcast, Rick Stollmeyer of Mindbody , Upasana Kamineni Konidela of Apollo Life, entrepreneur Jeffery Martin and Deepak Chopra, MD, of the Chopra Center and UC San Diego School of Medicine. Series: "Wellbeing " [Health and Medicine] [Business] [Show ID: 31529]
The Sages & Scientists Symposium presents a panel of experts led by Poonacha Machaiah, co-founder of Jiyo, in a discussion on how technology can improve wellness. Machaiah appears as a HumaGram, demonstratiing a new technology for participating in live events from remote locations. Other guests include James Mault, MD of Qualcomm Life, Paddy Barrett of Scripps Translational Science Institute, Paul Duffy of ARHT Media, Moira Burke of Facebook, Simon Leung of NetDragon, Sridhar Solur of Comcast, Rick Stollmeyer of Mindbody , Upasana Kamineni Konidela of Apollo Life, entrepreneur Jeffery Martin and Deepak Chopra, MD, of the Chopra Center and UC San Diego School of Medicine. Series: "Wellbeing " [Health and Medicine] [Business] [Show ID: 31529]
Dr. Steve Steinhubl Director of Digital Medicine, the Scripps Translational Science Institute talks about the NIH Precision Medicine Initiative (PMI) Cohort Program that will be officially launched this fall to recruit 1 million people in the most ambitious medical research program in US history. The goal is to create a rich data base feed by genetic information and patient data collected using smart phones and sensors to help define the new model for the future of healthcare. @ScrippsSTSI Scripps Translational Science Institute Go here to register to receive more information from NIH: PMI Cohort Program Participation
Paddy Barrett, MD is a clinical scholar at the Scripps Translational Science Institute, host of the podcast The Doctor Paradox, and co-author of an article in The Lancet on the 200th anniversary of the invention of the stethoscope. Paddy talks about the early resistance to the use of the stethoscope, advancements in mobile ultrasound devices, and benefits for doctors and patients to see real-time pictures and not just depend on faint sounds heard only by the highly trained. @Paddy_Barrett @paradox_doctor The Doctor Paradox To Truly Look Inside published in The Lancet Scripps Translational Science Institute (STSI)
Dr. Steve Steinhubl, Director of Digital Medicine, Scripps Translational Science Institute looks back on his recent conference on transforming medicine, reflects on how much more evidence is needed about the effectiveness of mobile health strategies and how eager researchers, doctors, and patients are for innovative uses of new technology to improve care. @SteveSteinhubl @ScrippsSTSI Scripps Translational Science Institute
Anna McCollister-Slipp, co-founder Galileo Analytics and Chief Advocate, Participatory Research, Scripps Translational Science Institute talks about using tools from the financial industry to analyze complex health data and leading research and development efforts into new scientific frontiers while enabling patients to actively pariticpate in their own treatments. @AnnaMcSlipp Galileo Analytics
Dr. Steven Steinhubl, Director of Digital Medicine, Scripps Translational Science Institute stsiweb.org @SteveSteinhubl Preview of the upcoming Transforming Medicine: Evidence-Driven mHealth conference where the goal will be to jumpstart efforts to drive development of evidence-based mobile health solutions.
We're in the middle of a healthcare revolution but it's about more than marvelous life-saving and life-enhancing apps on our smartphone. Eric Topol of the Scripps Translational Science Institute and author of The Patient Will See You Now argues that the digital revolution will give us more control of our health information and data. More powerful patients will transform the doctor-patient interaction. Topol talks with EconTalk host Russ Roberts about his new book giving us a glimpse of the changes coming to medicine from the digital revolution.
Today's guest is none other than cardiology superstar Eric Topol MD. He's the Chief Academic Officer of Scripps Health, Director of the Scripps Translational Science Institute, Editor in Chief of Medscape and theheart.org, he's the The Gary and Mary West Chair of Innovative Medicine, and co-founder of the West Wireless Health Institute to name just a few. At the young age of 36, Eric Topol was named Chairman of Cardiovascular Medicine at the Cleveland Clinic where he helped to catapult the institution into the leading ranks of the field. Eric has received so many honors that it's beyond the scope of this post to list them all. This is just a short excerpt: He was named Doctor of the Decade by the Institute for Scientific Information. In 2012 the journal „Modern Healthcare“ ranked him as the most influential physician executive in the US. In 2009 GQ magazine elected Eric to be one of 12 physcician rockstars. He was elected into the Institute of Medicine by the National Academy of Science and the list goes on and on. In 2012 he published the seminal Book "The crative desctruction of medicine“ that has been all over the media. It has become hugely popular especially among tech-savvy physicians. His book and his initiatives at Scripps have made him the figurehead of all things on the intersection of medicine and technology. So he's been featured and interviewed on popular TV show like Colbert Nation and his TED talk has been viewed over 600.000 times. He's been featured on the Economist, CSpan and Techcrunch. And even though he's such an acclaimed physician, he has remained approachable and ready to share his wisdom with the world. In this episode you will learn: What skills are most valuable for a young doctor What character traits will keep you from being successful What was the best advice he ever got from a mentor What he would recommend to his 20 year old self How to approach someone who could potentially become your mentor. What books Eric recommends How Eric spends his mornings How he keeps up with all the information overflow How Eric uses Twitter to stay productive and up-to-date What to do if you find yourself in a position that won't let you maximize your full potential How to stay motivated How Eric structures his mornings so he's energized and up-to-date How to choose the right projects to work on And much, much more
Donald Jones, Chief Digital Officer, Scripps Translational Science Institute talks with host Craig Lipset, Head of Clinical Innovation, R&D, Pfizer on what's happening with digital in drug development. Don discusses his thoughts on the evolution of new products with digital and the “digitazation” of tools for clinical trials. He also shares his thoughts on the biggest disruptors in pharma. Don and Craig will be featured in an interview as well at DPharm: Disruptive Innovations to Advance Clinical Trials on September 11, 2014 in Boston. Host Craig Lipset Head of Clinical Innovation, R&D Pfizer Guest Donald Jones Chief Digital Officer Scripps Translational Science Institute & Founder & Chairman, Wireless Life Sciences Alliance Producer Valerie Bowling Executive Director The Conference Forum
The Health Crossroad with Dr. Doug Elwood and Dr. Tom Elwood
Dr. Steven Steinhubl has a long and impressive array of leadership activities across health. He has held numerous positions as an educator, researcher, and clinician at hospitals including the Cleveland Clinic, in the Air Force, and within Geisinger Healthcare system. With over 200 peer-reviewed publications, book chapters, and abstracts, Dr. Steinhubl is currently the Director of Digital Medicine at the Scripps Translational Science Institute and a clinical cardiologist at Scripps Health. Dr. Steinhubl received his undergraduate training in chemical engineering at Purdue University in Indiana, graduate training in physiology at Georgetown University in Washington, DC, and his medical degree at St. Louis University in Missouri. In this interview, Dr. Steinhubl discusses the potential of mHealth and digital health working with Dr. Eric Topol, as well as payment reform.
In his new book The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care Eric Topol argues that medicine is set to undergo its biggest shakeup in history pushed by demanding consumers and the availability of game-changing technology. Topol -- a cardiologist director of the Scripps Translational Science Institute and co-founder of the West Wireless Health Institute in La Jolla Calif. -- was recently interviewed for Knowledge at Wharton by C. William Hanson III director surgical intensive care at the Hospital of the University of Pennsylvania. (Podcast with transcript) See acast.com/privacy for privacy and opt-out information.
Nicholas McConnell, PhD candidate in Astrophysics at UCB summer 2012, and Jeff Silverman, PhD of Astrophysics from UCB in 2011, part one of three, talk about exoplanets and the search for water in the universe. To help analyze data www.galaxyzoo.org or www.planethunters.orgTranscriptSpeaker 1: Spectrum's next [inaudible]. Welcome to spectrum science and technology show on k a l x Berkeley, [00:00:30] a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 2: Good afternoon. My name is Brad Swift. I'm joined today by spectrum contributors, Rick Karnofsky and Lisa Katovich. Our interview is with Jeff Silverman, a recent phd in astrophysics from UC Berkeley and Nicholas McConnell, a phd candidate unscheduled to be awarded his phd in astrophysics by UC Berkeley this summer. [00:01:00] Jeff and Nicholas have generously agreed to help spectrum present three shows on astronomy, explaining the big ideas, recent experiments, international collaborations and improvements and observations on technology that are transforming astronomy. In part one we discuss extra solar planets known as exoplanets and the search for liquid water in the universe. Nicholas McConnell and Jeff Silverman. Welcome to spectrum. Thanks for having us do. You're both astronomers. Yup. And today you're going to talk with us about [00:01:30] what's been happening in astronomy in say, the past five years that really stands out for you. That's very salient that you think's important. Nicholas, why don't you bring up the first topic that we're going to discuss here? Speaker 2: Sure. Well, there are many things to choose from, but for me, one of the most exciting things that I think has been happening is that over the last two or three years, thanks mostly to a NASA satellite called the Kepler mission. Astronomers have been discovering literally thousands of new planets orbiting other stars, uh, in our own galaxy every year. [00:02:00] And one particularly exciting discovery that happened in December, 2011 was we found a planet around another star that appeared to be in the so called habitable zone of that planet. The zone where the distance from the star was appropriate that the temperature on the planet could possibly be not too cold and not too hot to have liquid water. And how much of that exoplanet research is done here in the bay area? Quite a large amount. There's a large healthy exoplanet team in the UC Berkeley Astronomy Department, [00:02:30] and many scientists here are heavily involved in the Kepler mission besides this planet in the habitable zone. Speaker 2: Like Nicholas mentioned, thousands of planets have been discovered by this Kepler mission of all shapes and sizes from nearly earth size to Uranus and Neptune size. Did you put her in a little bit bigger orbiting their stars that are sun-like sometimes a little bit smaller, sometimes a little bit bigger than the sun at various distances. There's maybe a couple of examples where we've seen a system of a few planets that sort [00:03:00] of mimic the sizes of planets in our solar system at some of the distances, but most of these planets are found very close to their host star. Nothing like what we see in our own solar system, things that are the size of Jupiter and Saturn that are orbiting even closer than mercury. And so this is a huge weird question that's outstanding. People are trying to figure out how do you make these systems, how do you make these planetary systems and why are they so prevalent and so different from what we know in our own solar system. Speaker 2: And are there some sort of limitations to the [00:03:30] finding techniques to, to locate these planets that might sort of bias you towards finding these large close planets spoken like a true scientist? Yes, we are absolutely biased to find big planets that are very close to their stars. So the first handful of planets that were found were very big. These so-called hot Jupiters, very big Jupiter sized planets near their stars. We are definitely biased by the techniques to find these kinds of planets. Capillary is doing a bit of a better job finding smaller planets, finding them further out. And so we're getting into a point [00:04:00] in time where we're close to being able to find similar looking systems to the solar system, bigger planets further out earth planets around the distance of earth from the sun and we're not really finding them as often as you might expect. Speaker 2: And so it does seem still that even taking into account some of this bias that our solar system is a bit of an oddball now that's certainly may change in the next few years. This is a huge fast moving field, but right now we're still an odd ball. Yeah. I have to say that the, the Kepler mission was designed [00:04:30] so that over the course of the missions lifetime, which was roughly a three year time period, starting maybe 2010 and going through 2013 or so, it was designed so that over that period it could detect a planet, maybe twice the size of our earth but orbiting at star at the same distance that the earth orbits the sun. So capillary is definitely doing a better job than previous missions, finding planets that aren't quite as small as earth but are getting down in that region where we can say this plant is actually fairly similar to the planet earth. Speaker 2: And because we're now simply becoming [00:05:00] able to start to find planets like this, we can begin to say things about how common are earth like planets relative to these hot Jupiters that Jeff was talking about before when we had only detected the hot Jupiters, there was nothing we could say about their relative abundance in the universe compared to planets like the earth was their technology. And Kepler that made this possible. Was there a breakthrough somehow in the, the instrument? The thing Kepler does is it measures the brightness coming from a star [00:05:30] over and over and over again. Uh, and what happens is that if a planet passes in front of the star along the line of sight to Earth, it blocks a little bit of the disk of the star. And so the star gets very slightly fatter. But these differences in the stars brightness are smaller than a percent. Speaker 2: And so in order to pick out that signal that you need to have an instrument that can measure the brightness of a star very, very accurately, repeatedly over and over again and simply by having it outside ears, atmosphere, having it in space and all of the different instrumental [00:06:00] things they did inside that satellite enables Kepler to measure stellar brightnesses with more precision than any instrument that we'd done this for previously. Another interesting piece of technology that was something that they had to tackle. And it's still sort of one of the limitations actually of Kepler, is because you're measuring the brightness of thousands of stars many, many times over and over and over again. That's a huge amount of data, just pure raw pictures that you have floating on a spacecraft and you need to beam those down to earth, to big computers to hold those. Speaker 2: And so [00:06:30] one of the biggest limitations from my understanding is just the bandwidth. It is hard to move that ms send that many, you know, picture files basically from space down, you know, different satellites to big data centers on earth. And so they kind of do it in big bursts and in chunks and they only take certain subsets of the pictures of different stars. Very, very close, a little snapshot, postage stamps right around each of the stars that they're monitoring. And it's still huge amounts of data. Uh, and so this has been a big breakthrough for a number of different [00:07:00] astronomy discoveries, is the large amount of data being able to move it through the Internet, through fiber optics and storing it and going through it in a fast, efficient way. Do you know if there's any kind of preliminary data analysis actually on the coupler? Speaker 2: I'm not completely sure, but there is some, as far as I know, a basic calibrations and, and basic work that it does before it sends down some of the products. But looking, as Nicholas said, for these very slight amounts of dimming in the stars takes a lot of computing power [00:07:30] and fancy algorithms that are run on big machines back on earth. And one of the really interesting things that's actually been done with the Keppra or data is after this processing, after you have, um, sort of your reduced scientific measurements. Um, recently these data have been put on the Internet so that by crowdsourcing people can go, ah, I think the website is called Kepler Zoo. And look at the period, the, the patterns of brightness versus time for all of these different stars. Um, and humans can try to find patterns that the best computer algorithms have failed to find. Um, and [00:08:00] I think there is a space of patterns that computers don't do very well at, but humans are better at. Um, so we're using the public to try to get more planets, uh, than when we, we'd be able to do just the astronomy community by itself. Speaker 1: [inaudible] this is spectrum on k l x Berkeley. We are talking about exoplanets with Jeff Silverman and Nicholas McConnell [00:08:30] reflecting on coupler. How do you, Speaker 2: I think it's changed your worldview. The entire subfield and astronomy have of exoplanets. Planets around other stars effectively didn't exist until the mid to late nineties. So when I was in elementary school, it was nice to think about planets on around other stars and see it in the movies. But it was very scifi. Speaker 3: Fast forward to to mean in college, in the early two thousands [00:09:00] taking astronomy classes, astronomers had discovered a handful of these exoplanets. And I distinctly remember one of my professors saying, you know, we found a few, we're going to find some more in the future. One day you'll pick up the newspaper and the front page will be a picture of an exoplanet. And sure enough, a few years ago, Berkeley astronomers took a picture of an exoplanet and it made the front page newspaper. Uh, and I'll never forget seeing that picture on the front page of the newspaper, just like my professor in college predicted. This is a very fast moving field. We're going to find even more planets earth-like [00:09:30] around sunlight stars that could very well have liquid water. It'll possibly be not that rare to have an earth-like planet in the very near future. Personally, to me, I think it's great. It makes me hope that perhaps we can find an exact earth analog around a sun analog and perhaps there is intelligent life or some kind of life that we can find. And I think an amazing thing that astronomers can do for the world. Speaker 4: I think with the discovery of planets that are similar [00:10:00] to Earth or at least about the same sizes, or we're beginning to go from detecting one, then a couple to actually doing decent statistics where we can project how many have planets about the same size of earth exist, say in our galaxy. I tried to do a very, very rough calculation this morning. If you ask how many earth sized planets are there in the Milky Way, I think the answer is there's probably about a billion or a couple billion. And so I think that's just another interesting way of looking at how [00:10:30] earth is not necessarily unique environment in the universe, but just as we have so much diversity here on earth than in our galaxy. We have evidence now that there is space and room to have as much diversity possibly throughout our galaxy. So I think we really are getting a profound sense of just what kind of environment we have for possibly life and for different conditions, not only in our own solar system, but in this much larger piece of the universe that we're [00:11:00] only beginning to explore. Speaker 5: [inaudible]Speaker 6: you're listening to spectrum on k a l x, Berkeley. We are talking about astrophysics with Nicholas McConnell and Jeff Silverman. Speaker 5: [inaudible]Speaker 3: let's talk about water in the universe. So we've found quite a bit of water [00:11:30] in the universe, oddly enough, sort of starting on the biggest scales. There's, there's some nebulae, some clusters of gas and particles out in the universe that are huge reservoirs of water and sort of related huge reservoirs of alcohols, ethanol's, things like that. Coming a little bit closer to home and looking a little bit more recently. In the past maybe five or 10 years, there's been quite a few new detections, new possible detections, new lines of evidence of liquid water, ice water in our solar system in very interesting [00:12:00] places. One, the moon of Saturn known as, and Solidus is a very shiny, very bright object. It's very, very white, snowy, clean looking objects. A handful of craters have much less cratered than our own moon, a little smaller than our moon as well. Speaker 3: But it had some weird features to it. It looks kind of neat. And so the the Cassini spacecraft, which has been around exploring Saturn and its moon systems and its ring system for the past decade or so, did a few very close flybys of this very interesting moon in solidus [00:12:30] figured out that most of the surface is solid ice water, ice, ammonia, hydrocarbons, stuff as well. Also notice that there were geysers coming off of the surface, which we've seen geysers on a couple of other moons of Jupiter and Saturn, but these were kind of interesting and Cassini was there and we lucked out and Cassini actually flew through one of these geysers and got to detect the particles from the geyser itself, right? They're very direct institute measurements of what's in the guys there and it was mostly water and some ammonia, which was [00:13:00] interesting. And then there's evidence that there was actually more organic compounds in there and so possibly there, this could lead to life. Speaker 3: There could be some kind of bacteria down in the innards of in solidus. That's sort of pushing a a little bit, sort of the next step beyond what the evidence is actually telling us. But it's very, very tantalizing. Just about four or five years ago, a NASA panel on moons and moon explorations in the solar system said that in Solidus is probably the best possibility [00:13:30] for current life outside of earth in our own solar system. And the idea is that underneath this sort of very smooth, icy surface, there's probably a liquid ocean, mostly water, maybe a little bit of salt water, like I said, a little ammonia, some organic compounds, perhaps probably not gray whales and great white sharks. Probably not even little fish and shrimp, but it seems reasonable that there could be microscopic organisms, some kind of life, you know, to be determined. Speaker 3: But it's possible. [00:14:00] There's liquid water, there's reasonable conditions. It's not too salty, it's not too acidic, it's not too hot. And there does seem to be at least the building blocks, some of these organic compounds, perhaps one outstanding issue is how thick is this outer ice layer. So there's been some ideas of what we should send another mission that's just going to drill in there and it had the little submarine and go look around for fish and organisms, but we don't actually have a great handle on how thick that ice layer is. Uh, so Cassini is continuing to study this moon along with the [00:14:30] rest of the stuff in the Saturn system. Other moons, the planet itself, the Rings, uh, and we'll hopefully learn a little bit more about it, but they're already in the works, uh, both NASA, Japanese and European missions to go explore in salad. It's even more now if you want to go a little bit closer than Enceladus, one of the most promising planets areas in our solar system where Speaker 4: people have thought about the possibility of liquid water, where we certainly know that frozen water exists and where we have a headstart on [00:15:00] objects actually on the surface exploring is the planet Mars. And there've been some recent discoveries about both water in the past history of Mars and possibly salty liquid water, actually existing present day on Mars that are fueling a lot of excitement in the scientific community. Right now we have two different kinds of instruments that are doing fantastic observations of Mars. One of them is called the Mars or condescends orbiter. It is a satellite in orbit around Mars that can take fantastically detailed [00:15:30] photographs of the Martian surface. You can see features about a few feet across on the Martian surface with the satellite and then the other are the famous Mars Rovers. Spirit and opportunity spirit recently shut down, met its demise even though these two rovers outlasted their nominal mission timeline by a factor of 10 or so, Opportunity is still exploring the Martian surface and in both cases, instruments have found evidence for water on Mars. Speaker 4: In the case of opportunity. The rover fairly recently [00:16:00] discovered this mineral vein in a rock in a crater on Mars that scientists are pretty certain, could only have been created by liquid water flowing through a crack in the rocket, some ancient time and marches history and creating this particular mineral known as gypsum in certain variances what we use to make plaster of Paris here on Earth. So there is evidence that in particular Martian environments, there was almost certainly liquid water on Mars in the past. Combine that with theoretical models of how the planet and its atmosphere would have evolved over time. [00:16:30] And there are some pictures of ancient Mars being this sort of lush liquid water, much warmer environment than it is today. And so possibly Mars in its past was a hospitable environment for life. Although I'll emphasize we've, we have not yet detected any evidence of present day or fossilized life on Mars, but frankly, we haven't explored a very large fraction of that planet yet. Speaker 4: So I wouldn't be entirely surprised if some discovery came along in the future. Another very, very interesting observation on Mars coming [00:17:00] from the Mars reconnaissance orbiter is that looking over time at the edges of some of the craters on Mars in the warm seasons, they actually found stream like features that looked like dark streams were appearing on the edges of craters and over the course of the warm season as these craters were being more exposed to the sun and warming up a little bit, the streams lengthen as you might expect, little trickles of liquid water to flow downhill and based on mineral analysis which you can do using spectroscopy [00:17:30] from the orbiter and just generally the overall pattern of how these streams change with the seasons. We think that's good evidence that some sort of salty water was creating the streams. Unfortunately we were not able to directly detect water. What we see, it looks more to be like residue from a salt water stream where the water evaporated or where the water is just below the surface. But it seems that in certain seasons and certain places of the planet, there could actually be water and liquid form just at the surface or just below the surface [00:18:00] of Mars today. I mean if you have salt water on Mars, then I think there's at least some chance that you could have some kind of primitive life forum thriving in it. [inaudible] Speaker 3: it's been amazing in the last few years using the orbiter and the rovers on Mars, the different lines of evidence that we have for this ice, either on the surface or just below the surface centimeters below the surface, inches below the surface. And so NASA just recently launched a mission to head to Mars and even bigger rover, something like the size of a small car [00:18:30] that's going to go around and specifically look for water, look for organic molecules, building blocks of life in different parts than where we've already explored on Mars. Speaker 4: And that rover is called curiosity and it's supposed to land on the Martian surface this summer. Is there water on the moon? Our Moon, there is water on the moon in the form of hydrous molecules, so where water is directly incorporated into a solid rock, but I don't think there's any evidence for frozen or liquid water on the moon, [00:19:00] certainly not liquid water. Speaker 5: [inaudible]Speaker 4: can you reflect on the importance of water being discovered in our solar system or in some other solar system or galaxy? Speaker 2: Clearly on earth, water is essential [00:19:30] for all life forms and so whereas there are ideas about exotic kinds of life that could exist without our requirement of having water. It certainly seems like the most natural place to start looking for life outside of our own planet. So knowing that it exists in liquid form in different places in the universe and knowing Lisa in our own solar system where it exists is I think a really good start toward actually doing an Ernest search for life outside earth, maybe in our own solar system. [00:20:00] And I think just knowing how much water there actually is in our universe makes it seem like the universe is maybe a friendlier place than we thought it was. Okay. Speaker 3: One of the basic questions in astronomy of humanity, one of the things that got me interested in astronomy originally was are we alone in the universe? Is there life out there in the solar system, in our galaxy, and looking for water is probably the best way, the most direct way to find where that life could be. Being able to go visit Mars, the Moon, various [00:20:30] moons in our own solar system. Looking for that life in the water or around the water, I think is is something that's a fundamental question for all humankind, not just scientists and astronomers. Speaker 7: That ends one, Jeff Silverman and Nicholas McConnell. We'll be back with part two on our next show. We'll talk about Super Novi and black holes. Rick Karnofsky and Lisa Catholic joined me [00:21:00] for the calendar and the new black hole, Speaker 8: the harmonic oscillators of the 21st century presented by Andrew Strom and dear professor of physics, Harvard University, Monday, March 12th at four 15 to 5:30 PM La Conte Hall Room Number One in the 20th century. Many problems across all of physics were solved by perturb native methods which reduce them to harmonic oscillators. Black holes are poised to play a similar role for the problems of 21st century physics. They are at once [00:21:30] the simplest and most complex objects in the physical universe. Professors durometer will give an introduction to the subject intended for a general audience Speaker 9: daily and Nardo art science evening rendezvous or laser is a monthly series of lectures, presentations, and networking between artists and scientists. This month, laser is on Monday, March 12th at the [inaudible] room of the front building at the University of San Francisco to one 30 zero Fulton Street. It is free, but [00:22:00] please RSVP to p at [inaudible] dot com the event starts at seven with a talk by [inaudible] Viskontas on the art and neuroscience of effective music performance. What is it about this art form that draws people in? What distinguishes a performance that is technically accurate but unmusical from one that elicits the chills. We will explore how music engages the brain and why it continues to be a worldwide addiction. This will be followed by Rebecca Cayman's talk, making the invisible visible [00:22:30] discoveries between art and science, the history of artists as scientists and scientists as artists will be shared drying from the collections of the American philosophical society and the Chemical Heritage Foundation. The development of new art science collaborations will also be discussed. Shawmut caught true of the Stanford Physics Department. We'll speak on are there more dimensions of space which we'll discuss how the extra dimensions proposed by some models such as string theory may explain and unify puzzles [00:23:00] of modern physics. The night we'll conclude with Scott killed doll and Nathaniel stern who will discuss beaming Twitter messages to glaze five eight one D and exoplanet 20 light years away that can support extra terrestrial life using DIY technology. The website for laser is www.leonardo.info Speaker 8: the creative destruction of medicine Wednesday, March 14th at 6:00 PM at the Commonwealth Club of San Francisco on the second [00:23:30] floor of five 95 market street, Eric Topol, MD, director of the Scripps Translational Science Institute, Co founder and vice chairman of the West Wireless Health Institute and author of the creative destruction of medicine. Dr Topol says that is poised to go through its biggest shakeup in history and unprecedented convergence of technologies such as the ability to digitize human genomes and the invention of wireless tools is gaining momentum, thrusting the medical field into the digital era. Tickets are $20 [00:24:00] for general public, $8 for members and $7 for students. Speaker 9: Ask a scientist is hosting a puzzle party on Pi Day Wednesday, March 14th at 7:00 PM this is a math and logic puzzle competition for teams of up to six people. It is free, but you're encouraged to support the venue by purchasing foods and or drinks. The winning team will get a round of drinks and an overwhelming sense of pride. Bring a jacket in case there is overflow onto the sidewalk of the bizarre [00:24:30] cafe. Five nine two seven California at 21st in San Francisco visit. Ask a scientist sf.com for more info. Speaker 7: Yeah, Speaker 6: the March Science at cal lecture will be given at 11:00 AM on Saturday, March 17th in the genetics and plant biology building room 100 the talk will be given by Dr Hazel Bane and is entitled The Sun a star in our own backyard. Dr Bain is a post doc with the Ruben Rahmati high energy spectroscopic [00:25:00] solar imager solar physics group at the Space Sciences Laboratory at UC Berkeley. Her main area of research involves studying solar eruptive events such as flares, jets, and coronal mass ejections using both space and ground-based instruments. In describing her talk, Dr Bane said the stars in the night sky have always been a source of intrigue and wonder with our very own star at the center of our solar system, the sun offers us a unique [00:25:30] opportunity to study the inner workings of these giant balls of plasma. Starting at the core, I will discuss the processes occurring at the different layers of the sun onto news. Speaker 9: The four mile long t veteran particle accelerator at Chicago's Fermi lab was closed in September, 2011 after being one of the most powerful accelerators for 20 years, but in analyzing 500 trillion subatomic particles, Asians from the CDF and DCO, the team says that they may [00:26:00] have generated about a thousand Higgs Bosons the particle that is responsible for mass in the standard model of physics in a previous episode of spectrum that you can download from iTunes you, we interviewed Dr Simoni Pig Ingreso about the hunt for the Higgs. The probability of these measurements being due to a statistical fluke instead of the measurements of the Higgs is about one in 30 or about 2.2 sigma. This is well below the one chance in 3.5 million or five sigma that will be used to claim the actual discovery of the Higgs. [00:26:30] The energy of the detected events is between 115 billion and 135 billion electron volts, which is in good agreement with the range of 124 billion electron volts to 126 billion electron volts that turns large. Hadron collider established with 3.6 sigma certainty. The large Hadron collider is on winter break, but we'll be fixed up again in April to continue trying to find the Higgs with five sigma certainty. Speaker 8: The Cal Energy Corp is offering internships [00:27:00] around the world from Brazil to Germany to Ghana, to China, as well as in the bay area. During the summer of 2012 internships will offer UC Berkeley undergraduates the opportunity to pursue challenging hands on projects and energy and climate research. According to the office of the vice chancellor for research among the projects, cal energy core interns will be involved in our efforts to create green coal as industrial fuel, helping to produce biofuels, working on improving photovoltaics for integration into the [00:27:30] electricity grid, building models to better understand climate change and designing and testing. Cookstoves. The internship program provides a $600 weekly stipend for all interns as well as funding to cover transportation and housing. All placements are full time, more information and application forms are available at the cow energy core website. Speaker 9: Yeah, Speaker 6: explaining science to an 11 year old. The flame challenge sponsored by the Center for communicating science is an attempt to reach the very core of [00:28:00] science communication. The contest asks scientists and generally clever people to submit their own explanations of what a flame is, explanations that would captivate an 11 year old. The flame challenge contest is open for entries between March 2nd and April 2nd with the winners to be announced in June. Entries can be in writing, video or graphics and they can be playful or serious as long as they are accurate and connect with the young judges. For more information and entry [00:28:30] forms, visit the challenge website. Flame challenge.org Speaker 7: [inaudible] music curse during the show goes by on Donna David [inaudible] on for his album title folk and acoustic [00:29:00] just made available by creative Commons license 3.0 contribution. [inaudible]. Thank you for listening to spectrum. If you have comments about the show [inaudible] [00:29:30] to our email address is [inaudible] means in two weeks. It's Speaker 6: the same Speaker 5: [inaudible]. Hosted on Acast. See acast.com/privacy for more information.
Nicholas McConnell, PhD candidate in Astrophysics at UCB summer 2012, and Jeff Silverman, PhD of Astrophysics from UCB in 2011, part one of three, talk about exoplanets and the search for water in the universe. To help analyze data www.galaxyzoo.org or www.planethunters.orgTranscriptSpeaker 1: Spectrum's next [inaudible]. Welcome to spectrum science and technology show on k a l x Berkeley, [00:00:30] a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 2: Good afternoon. My name is Brad Swift. I'm joined today by spectrum contributors, Rick Karnofsky and Lisa Katovich. Our interview is with Jeff Silverman, a recent phd in astrophysics from UC Berkeley and Nicholas McConnell, a phd candidate unscheduled to be awarded his phd in astrophysics by UC Berkeley this summer. [00:01:00] Jeff and Nicholas have generously agreed to help spectrum present three shows on astronomy, explaining the big ideas, recent experiments, international collaborations and improvements and observations on technology that are transforming astronomy. In part one we discuss extra solar planets known as exoplanets and the search for liquid water in the universe. Nicholas McConnell and Jeff Silverman. Welcome to spectrum. Thanks for having us do. You're both astronomers. Yup. And today you're going to talk with us about [00:01:30] what's been happening in astronomy in say, the past five years that really stands out for you. That's very salient that you think's important. Nicholas, why don't you bring up the first topic that we're going to discuss here? Speaker 2: Sure. Well, there are many things to choose from, but for me, one of the most exciting things that I think has been happening is that over the last two or three years, thanks mostly to a NASA satellite called the Kepler mission. Astronomers have been discovering literally thousands of new planets orbiting other stars, uh, in our own galaxy every year. [00:02:00] And one particularly exciting discovery that happened in December, 2011 was we found a planet around another star that appeared to be in the so called habitable zone of that planet. The zone where the distance from the star was appropriate that the temperature on the planet could possibly be not too cold and not too hot to have liquid water. And how much of that exoplanet research is done here in the bay area? Quite a large amount. There's a large healthy exoplanet team in the UC Berkeley Astronomy Department, [00:02:30] and many scientists here are heavily involved in the Kepler mission besides this planet in the habitable zone. Speaker 2: Like Nicholas mentioned, thousands of planets have been discovered by this Kepler mission of all shapes and sizes from nearly earth size to Uranus and Neptune size. Did you put her in a little bit bigger orbiting their stars that are sun-like sometimes a little bit smaller, sometimes a little bit bigger than the sun at various distances. There's maybe a couple of examples where we've seen a system of a few planets that sort [00:03:00] of mimic the sizes of planets in our solar system at some of the distances, but most of these planets are found very close to their host star. Nothing like what we see in our own solar system, things that are the size of Jupiter and Saturn that are orbiting even closer than mercury. And so this is a huge weird question that's outstanding. People are trying to figure out how do you make these systems, how do you make these planetary systems and why are they so prevalent and so different from what we know in our own solar system. Speaker 2: And are there some sort of limitations to the [00:03:30] finding techniques to, to locate these planets that might sort of bias you towards finding these large close planets spoken like a true scientist? Yes, we are absolutely biased to find big planets that are very close to their stars. So the first handful of planets that were found were very big. These so-called hot Jupiters, very big Jupiter sized planets near their stars. We are definitely biased by the techniques to find these kinds of planets. Capillary is doing a bit of a better job finding smaller planets, finding them further out. And so we're getting into a point [00:04:00] in time where we're close to being able to find similar looking systems to the solar system, bigger planets further out earth planets around the distance of earth from the sun and we're not really finding them as often as you might expect. Speaker 2: And so it does seem still that even taking into account some of this bias that our solar system is a bit of an oddball now that's certainly may change in the next few years. This is a huge fast moving field, but right now we're still an odd ball. Yeah. I have to say that the, the Kepler mission was designed [00:04:30] so that over the course of the missions lifetime, which was roughly a three year time period, starting maybe 2010 and going through 2013 or so, it was designed so that over that period it could detect a planet, maybe twice the size of our earth but orbiting at star at the same distance that the earth orbits the sun. So capillary is definitely doing a better job than previous missions, finding planets that aren't quite as small as earth but are getting down in that region where we can say this plant is actually fairly similar to the planet earth. Speaker 2: And because we're now simply becoming [00:05:00] able to start to find planets like this, we can begin to say things about how common are earth like planets relative to these hot Jupiters that Jeff was talking about before when we had only detected the hot Jupiters, there was nothing we could say about their relative abundance in the universe compared to planets like the earth was their technology. And Kepler that made this possible. Was there a breakthrough somehow in the, the instrument? The thing Kepler does is it measures the brightness coming from a star [00:05:30] over and over and over again. Uh, and what happens is that if a planet passes in front of the star along the line of sight to Earth, it blocks a little bit of the disk of the star. And so the star gets very slightly fatter. But these differences in the stars brightness are smaller than a percent. Speaker 2: And so in order to pick out that signal that you need to have an instrument that can measure the brightness of a star very, very accurately, repeatedly over and over again and simply by having it outside ears, atmosphere, having it in space and all of the different instrumental [00:06:00] things they did inside that satellite enables Kepler to measure stellar brightnesses with more precision than any instrument that we'd done this for previously. Another interesting piece of technology that was something that they had to tackle. And it's still sort of one of the limitations actually of Kepler, is because you're measuring the brightness of thousands of stars many, many times over and over and over again. That's a huge amount of data, just pure raw pictures that you have floating on a spacecraft and you need to beam those down to earth, to big computers to hold those. Speaker 2: And so [00:06:30] one of the biggest limitations from my understanding is just the bandwidth. It is hard to move that ms send that many, you know, picture files basically from space down, you know, different satellites to big data centers on earth. And so they kind of do it in big bursts and in chunks and they only take certain subsets of the pictures of different stars. Very, very close, a little snapshot, postage stamps right around each of the stars that they're monitoring. And it's still huge amounts of data. Uh, and so this has been a big breakthrough for a number of different [00:07:00] astronomy discoveries, is the large amount of data being able to move it through the Internet, through fiber optics and storing it and going through it in a fast, efficient way. Do you know if there's any kind of preliminary data analysis actually on the coupler? Speaker 2: I'm not completely sure, but there is some, as far as I know, a basic calibrations and, and basic work that it does before it sends down some of the products. But looking, as Nicholas said, for these very slight amounts of dimming in the stars takes a lot of computing power [00:07:30] and fancy algorithms that are run on big machines back on earth. And one of the really interesting things that's actually been done with the Keppra or data is after this processing, after you have, um, sort of your reduced scientific measurements. Um, recently these data have been put on the Internet so that by crowdsourcing people can go, ah, I think the website is called Kepler Zoo. And look at the period, the, the patterns of brightness versus time for all of these different stars. Um, and humans can try to find patterns that the best computer algorithms have failed to find. Um, and [00:08:00] I think there is a space of patterns that computers don't do very well at, but humans are better at. Um, so we're using the public to try to get more planets, uh, than when we, we'd be able to do just the astronomy community by itself. Speaker 1: [inaudible] this is spectrum on k l x Berkeley. We are talking about exoplanets with Jeff Silverman and Nicholas McConnell [00:08:30] reflecting on coupler. How do you, Speaker 2: I think it's changed your worldview. The entire subfield and astronomy have of exoplanets. Planets around other stars effectively didn't exist until the mid to late nineties. So when I was in elementary school, it was nice to think about planets on around other stars and see it in the movies. But it was very scifi. Speaker 3: Fast forward to to mean in college, in the early two thousands [00:09:00] taking astronomy classes, astronomers had discovered a handful of these exoplanets. And I distinctly remember one of my professors saying, you know, we found a few, we're going to find some more in the future. One day you'll pick up the newspaper and the front page will be a picture of an exoplanet. And sure enough, a few years ago, Berkeley astronomers took a picture of an exoplanet and it made the front page newspaper. Uh, and I'll never forget seeing that picture on the front page of the newspaper, just like my professor in college predicted. This is a very fast moving field. We're going to find even more planets earth-like [00:09:30] around sunlight stars that could very well have liquid water. It'll possibly be not that rare to have an earth-like planet in the very near future. Personally, to me, I think it's great. It makes me hope that perhaps we can find an exact earth analog around a sun analog and perhaps there is intelligent life or some kind of life that we can find. And I think an amazing thing that astronomers can do for the world. Speaker 4: I think with the discovery of planets that are similar [00:10:00] to Earth or at least about the same sizes, or we're beginning to go from detecting one, then a couple to actually doing decent statistics where we can project how many have planets about the same size of earth exist, say in our galaxy. I tried to do a very, very rough calculation this morning. If you ask how many earth sized planets are there in the Milky Way, I think the answer is there's probably about a billion or a couple billion. And so I think that's just another interesting way of looking at how [00:10:30] earth is not necessarily unique environment in the universe, but just as we have so much diversity here on earth than in our galaxy. We have evidence now that there is space and room to have as much diversity possibly throughout our galaxy. So I think we really are getting a profound sense of just what kind of environment we have for possibly life and for different conditions, not only in our own solar system, but in this much larger piece of the universe that we're [00:11:00] only beginning to explore. Speaker 5: [inaudible]Speaker 6: you're listening to spectrum on k a l x, Berkeley. We are talking about astrophysics with Nicholas McConnell and Jeff Silverman. Speaker 5: [inaudible]Speaker 3: let's talk about water in the universe. So we've found quite a bit of water [00:11:30] in the universe, oddly enough, sort of starting on the biggest scales. There's, there's some nebulae, some clusters of gas and particles out in the universe that are huge reservoirs of water and sort of related huge reservoirs of alcohols, ethanol's, things like that. Coming a little bit closer to home and looking a little bit more recently. In the past maybe five or 10 years, there's been quite a few new detections, new possible detections, new lines of evidence of liquid water, ice water in our solar system in very interesting [00:12:00] places. One, the moon of Saturn known as, and Solidus is a very shiny, very bright object. It's very, very white, snowy, clean looking objects. A handful of craters have much less cratered than our own moon, a little smaller than our moon as well. Speaker 3: But it had some weird features to it. It looks kind of neat. And so the the Cassini spacecraft, which has been around exploring Saturn and its moon systems and its ring system for the past decade or so, did a few very close flybys of this very interesting moon in solidus [00:12:30] figured out that most of the surface is solid ice water, ice, ammonia, hydrocarbons, stuff as well. Also notice that there were geysers coming off of the surface, which we've seen geysers on a couple of other moons of Jupiter and Saturn, but these were kind of interesting and Cassini was there and we lucked out and Cassini actually flew through one of these geysers and got to detect the particles from the geyser itself, right? They're very direct institute measurements of what's in the guys there and it was mostly water and some ammonia, which was [00:13:00] interesting. And then there's evidence that there was actually more organic compounds in there and so possibly there, this could lead to life. Speaker 3: There could be some kind of bacteria down in the innards of in solidus. That's sort of pushing a a little bit, sort of the next step beyond what the evidence is actually telling us. But it's very, very tantalizing. Just about four or five years ago, a NASA panel on moons and moon explorations in the solar system said that in Solidus is probably the best possibility [00:13:30] for current life outside of earth in our own solar system. And the idea is that underneath this sort of very smooth, icy surface, there's probably a liquid ocean, mostly water, maybe a little bit of salt water, like I said, a little ammonia, some organic compounds, perhaps probably not gray whales and great white sharks. Probably not even little fish and shrimp, but it seems reasonable that there could be microscopic organisms, some kind of life, you know, to be determined. Speaker 3: But it's possible. [00:14:00] There's liquid water, there's reasonable conditions. It's not too salty, it's not too acidic, it's not too hot. And there does seem to be at least the building blocks, some of these organic compounds, perhaps one outstanding issue is how thick is this outer ice layer. So there's been some ideas of what we should send another mission that's just going to drill in there and it had the little submarine and go look around for fish and organisms, but we don't actually have a great handle on how thick that ice layer is. Uh, so Cassini is continuing to study this moon along with the [00:14:30] rest of the stuff in the Saturn system. Other moons, the planet itself, the Rings, uh, and we'll hopefully learn a little bit more about it, but they're already in the works, uh, both NASA, Japanese and European missions to go explore in salad. It's even more now if you want to go a little bit closer than Enceladus, one of the most promising planets areas in our solar system where Speaker 4: people have thought about the possibility of liquid water, where we certainly know that frozen water exists and where we have a headstart on [00:15:00] objects actually on the surface exploring is the planet Mars. And there've been some recent discoveries about both water in the past history of Mars and possibly salty liquid water, actually existing present day on Mars that are fueling a lot of excitement in the scientific community. Right now we have two different kinds of instruments that are doing fantastic observations of Mars. One of them is called the Mars or condescends orbiter. It is a satellite in orbit around Mars that can take fantastically detailed [00:15:30] photographs of the Martian surface. You can see features about a few feet across on the Martian surface with the satellite and then the other are the famous Mars Rovers. Spirit and opportunity spirit recently shut down, met its demise even though these two rovers outlasted their nominal mission timeline by a factor of 10 or so, Opportunity is still exploring the Martian surface and in both cases, instruments have found evidence for water on Mars. Speaker 4: In the case of opportunity. The rover fairly recently [00:16:00] discovered this mineral vein in a rock in a crater on Mars that scientists are pretty certain, could only have been created by liquid water flowing through a crack in the rocket, some ancient time and marches history and creating this particular mineral known as gypsum in certain variances what we use to make plaster of Paris here on Earth. So there is evidence that in particular Martian environments, there was almost certainly liquid water on Mars in the past. Combine that with theoretical models of how the planet and its atmosphere would have evolved over time. [00:16:30] And there are some pictures of ancient Mars being this sort of lush liquid water, much warmer environment than it is today. And so possibly Mars in its past was a hospitable environment for life. Although I'll emphasize we've, we have not yet detected any evidence of present day or fossilized life on Mars, but frankly, we haven't explored a very large fraction of that planet yet. Speaker 4: So I wouldn't be entirely surprised if some discovery came along in the future. Another very, very interesting observation on Mars coming [00:17:00] from the Mars reconnaissance orbiter is that looking over time at the edges of some of the craters on Mars in the warm seasons, they actually found stream like features that looked like dark streams were appearing on the edges of craters and over the course of the warm season as these craters were being more exposed to the sun and warming up a little bit, the streams lengthen as you might expect, little trickles of liquid water to flow downhill and based on mineral analysis which you can do using spectroscopy [00:17:30] from the orbiter and just generally the overall pattern of how these streams change with the seasons. We think that's good evidence that some sort of salty water was creating the streams. Unfortunately we were not able to directly detect water. What we see, it looks more to be like residue from a salt water stream where the water evaporated or where the water is just below the surface. But it seems that in certain seasons and certain places of the planet, there could actually be water and liquid form just at the surface or just below the surface [00:18:00] of Mars today. I mean if you have salt water on Mars, then I think there's at least some chance that you could have some kind of primitive life forum thriving in it. [inaudible] Speaker 3: it's been amazing in the last few years using the orbiter and the rovers on Mars, the different lines of evidence that we have for this ice, either on the surface or just below the surface centimeters below the surface, inches below the surface. And so NASA just recently launched a mission to head to Mars and even bigger rover, something like the size of a small car [00:18:30] that's going to go around and specifically look for water, look for organic molecules, building blocks of life in different parts than where we've already explored on Mars. Speaker 4: And that rover is called curiosity and it's supposed to land on the Martian surface this summer. Is there water on the moon? Our Moon, there is water on the moon in the form of hydrous molecules, so where water is directly incorporated into a solid rock, but I don't think there's any evidence for frozen or liquid water on the moon, [00:19:00] certainly not liquid water. Speaker 5: [inaudible]Speaker 4: can you reflect on the importance of water being discovered in our solar system or in some other solar system or galaxy? Speaker 2: Clearly on earth, water is essential [00:19:30] for all life forms and so whereas there are ideas about exotic kinds of life that could exist without our requirement of having water. It certainly seems like the most natural place to start looking for life outside of our own planet. So knowing that it exists in liquid form in different places in the universe and knowing Lisa in our own solar system where it exists is I think a really good start toward actually doing an Ernest search for life outside earth, maybe in our own solar system. [00:20:00] And I think just knowing how much water there actually is in our universe makes it seem like the universe is maybe a friendlier place than we thought it was. Okay. Speaker 3: One of the basic questions in astronomy of humanity, one of the things that got me interested in astronomy originally was are we alone in the universe? Is there life out there in the solar system, in our galaxy, and looking for water is probably the best way, the most direct way to find where that life could be. Being able to go visit Mars, the Moon, various [00:20:30] moons in our own solar system. Looking for that life in the water or around the water, I think is is something that's a fundamental question for all humankind, not just scientists and astronomers. Speaker 7: That ends one, Jeff Silverman and Nicholas McConnell. We'll be back with part two on our next show. We'll talk about Super Novi and black holes. Rick Karnofsky and Lisa Catholic joined me [00:21:00] for the calendar and the new black hole, Speaker 8: the harmonic oscillators of the 21st century presented by Andrew Strom and dear professor of physics, Harvard University, Monday, March 12th at four 15 to 5:30 PM La Conte Hall Room Number One in the 20th century. Many problems across all of physics were solved by perturb native methods which reduce them to harmonic oscillators. Black holes are poised to play a similar role for the problems of 21st century physics. They are at once [00:21:30] the simplest and most complex objects in the physical universe. Professors durometer will give an introduction to the subject intended for a general audience Speaker 9: daily and Nardo art science evening rendezvous or laser is a monthly series of lectures, presentations, and networking between artists and scientists. This month, laser is on Monday, March 12th at the [inaudible] room of the front building at the University of San Francisco to one 30 zero Fulton Street. It is free, but [00:22:00] please RSVP to p at [inaudible] dot com the event starts at seven with a talk by [inaudible] Viskontas on the art and neuroscience of effective music performance. What is it about this art form that draws people in? What distinguishes a performance that is technically accurate but unmusical from one that elicits the chills. We will explore how music engages the brain and why it continues to be a worldwide addiction. This will be followed by Rebecca Cayman's talk, making the invisible visible [00:22:30] discoveries between art and science, the history of artists as scientists and scientists as artists will be shared drying from the collections of the American philosophical society and the Chemical Heritage Foundation. The development of new art science collaborations will also be discussed. Shawmut caught true of the Stanford Physics Department. We'll speak on are there more dimensions of space which we'll discuss how the extra dimensions proposed by some models such as string theory may explain and unify puzzles [00:23:00] of modern physics. The night we'll conclude with Scott killed doll and Nathaniel stern who will discuss beaming Twitter messages to glaze five eight one D and exoplanet 20 light years away that can support extra terrestrial life using DIY technology. The website for laser is www.leonardo.info Speaker 8: the creative destruction of medicine Wednesday, March 14th at 6:00 PM at the Commonwealth Club of San Francisco on the second [00:23:30] floor of five 95 market street, Eric Topol, MD, director of the Scripps Translational Science Institute, Co founder and vice chairman of the West Wireless Health Institute and author of the creative destruction of medicine. Dr Topol says that is poised to go through its biggest shakeup in history and unprecedented convergence of technologies such as the ability to digitize human genomes and the invention of wireless tools is gaining momentum, thrusting the medical field into the digital era. Tickets are $20 [00:24:00] for general public, $8 for members and $7 for students. Speaker 9: Ask a scientist is hosting a puzzle party on Pi Day Wednesday, March 14th at 7:00 PM this is a math and logic puzzle competition for teams of up to six people. It is free, but you're encouraged to support the venue by purchasing foods and or drinks. The winning team will get a round of drinks and an overwhelming sense of pride. Bring a jacket in case there is overflow onto the sidewalk of the bizarre [00:24:30] cafe. Five nine two seven California at 21st in San Francisco visit. Ask a scientist sf.com for more info. Speaker 7: Yeah, Speaker 6: the March Science at cal lecture will be given at 11:00 AM on Saturday, March 17th in the genetics and plant biology building room 100 the talk will be given by Dr Hazel Bane and is entitled The Sun a star in our own backyard. Dr Bain is a post doc with the Ruben Rahmati high energy spectroscopic [00:25:00] solar imager solar physics group at the Space Sciences Laboratory at UC Berkeley. Her main area of research involves studying solar eruptive events such as flares, jets, and coronal mass ejections using both space and ground-based instruments. In describing her talk, Dr Bane said the stars in the night sky have always been a source of intrigue and wonder with our very own star at the center of our solar system, the sun offers us a unique [00:25:30] opportunity to study the inner workings of these giant balls of plasma. Starting at the core, I will discuss the processes occurring at the different layers of the sun onto news. Speaker 9: The four mile long t veteran particle accelerator at Chicago's Fermi lab was closed in September, 2011 after being one of the most powerful accelerators for 20 years, but in analyzing 500 trillion subatomic particles, Asians from the CDF and DCO, the team says that they may [00:26:00] have generated about a thousand Higgs Bosons the particle that is responsible for mass in the standard model of physics in a previous episode of spectrum that you can download from iTunes you, we interviewed Dr Simoni Pig Ingreso about the hunt for the Higgs. The probability of these measurements being due to a statistical fluke instead of the measurements of the Higgs is about one in 30 or about 2.2 sigma. This is well below the one chance in 3.5 million or five sigma that will be used to claim the actual discovery of the Higgs. [00:26:30] The energy of the detected events is between 115 billion and 135 billion electron volts, which is in good agreement with the range of 124 billion electron volts to 126 billion electron volts that turns large. Hadron collider established with 3.6 sigma certainty. The large Hadron collider is on winter break, but we'll be fixed up again in April to continue trying to find the Higgs with five sigma certainty. Speaker 8: The Cal Energy Corp is offering internships [00:27:00] around the world from Brazil to Germany to Ghana, to China, as well as in the bay area. During the summer of 2012 internships will offer UC Berkeley undergraduates the opportunity to pursue challenging hands on projects and energy and climate research. According to the office of the vice chancellor for research among the projects, cal energy core interns will be involved in our efforts to create green coal as industrial fuel, helping to produce biofuels, working on improving photovoltaics for integration into the [00:27:30] electricity grid, building models to better understand climate change and designing and testing. Cookstoves. The internship program provides a $600 weekly stipend for all interns as well as funding to cover transportation and housing. All placements are full time, more information and application forms are available at the cow energy core website. Speaker 9: Yeah, Speaker 6: explaining science to an 11 year old. The flame challenge sponsored by the Center for communicating science is an attempt to reach the very core of [00:28:00] science communication. The contest asks scientists and generally clever people to submit their own explanations of what a flame is, explanations that would captivate an 11 year old. The flame challenge contest is open for entries between March 2nd and April 2nd with the winners to be announced in June. Entries can be in writing, video or graphics and they can be playful or serious as long as they are accurate and connect with the young judges. For more information and entry [00:28:30] forms, visit the challenge website. Flame challenge.org Speaker 7: [inaudible] music curse during the show goes by on Donna David [inaudible] on for his album title folk and acoustic [00:29:00] just made available by creative Commons license 3.0 contribution. [inaudible]. Thank you for listening to spectrum. If you have comments about the show [inaudible] [00:29:30] to our email address is [inaudible] means in two weeks. It's Speaker 6: the same Speaker 5: [inaudible]. See acast.com/privacy for privacy and opt-out information.
Guest: Eric Topol, MD Host: Timothy Bailey, MD The challenges of treating diabetes include long-term monitoring and management, lifestyle change and adherence to medication. How are digital technology and genomics shaping the management of diabetes? Join guest host Dr. Timothy Bailey and his guest Dr. Eric Topol, director of the Scripps Translational Science Institute, as they discuss how digital technologies can improve glucose monitoring and genomics is leading to individualized treatment. Dr. Topol, who does not have diabetes, describes his personal experience living with continuous glucose monitoring for one week. Disclosures Dr. Eric Topol has disclosed that he has received grants for clinical research from sanofi-avenitis. Dr. Topol has also disclosed that he has served as an advisor or consultant to sanofi-aventis and Daiichi Sankyo.