Podcasts about front immunol

ReferencesMol Cell Biol . 2002 Nov;22(22):7758–7768.Front Immunol. 2023; 14: 1151166. Guerra, DJ.2025. Unpublished lecturesBlood . 2017 Nov 30;130(22):2401-2409Blood.2021. 138, Issue 13, Pages 1120-1136Case Reports Immunol. 2020 Aug 26:8841571.Roy Rogers & Dale Evans 1952. "Happy Trails"https://music.youtube.com/watch?v=oG_fSoYFWLA&si=3iDBktoWNVX5LIsdCrew and Guidio.1967. "Cant Take my Eyes Off of You"https://music.youtube.com/watch?v=J36z7AnhvOM&si=M4co5ohwtNGbxV1fPreitti, Creatore and Weiss 1961"Cant Help Falling in Love with You". Elvishttps://music.youtube.com/watch?v=TlrNxJqODBc&si=59b1Bu5zBuW1cNjwMozart, WA. 1785. Piano Concerto #22.in EMajor. K482https://music.youtube.com/watch?v=OWFM3K8jOco&si=A6UiMJ4rmWCYyP3t.

Cindy Hutchens describes her experiences living with SLE and her interactions with the healthcare system along the way. Resources & References 1) Lupus Foundation of America (LFA) 2) The Lupus Book by Daniel Wallace 3) LFA Mid-South Chapter, Nashville, TN 4) LFA Walk to End Lupus Now 5) Jog NR, James JA. Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus. Front Immunol. 2021 Feb 3;11:623944. doi: 10.3389/fimmu.2020.623944. PMID: 33613559; PMCID: PMC7886683. 6) Ünlü O, Zuily S, Erkan D. The clinical significance of antiphospholipid antibodies in systemic lupus erythematosus. Eur J Rheumatol. 2016 Jun;3(2):75-84. doi: 10.5152/eurjrheum.2015.0085. Epub 2015 Dec 29. PMID: 27708976; PMCID: PMC5042235. 7) Benlysta prescribing information 8) Rexulti prescribing information 9) Aplenzin prescribing information

From the Viruses of Microbes meeting in Cairns, Australia, TWiV speaks with Krystyna and Rob about their research on using bacteriophages to treat bacterial infections. Hosts: Vincent Racaniello and Jolene Ramsey Guests: Krystyna Dabrowska and Rob Lavigne Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Viruses of Microbes 2024 Immune responses to phages (Front Immunol) Engineering bacteriolytic enzymes (Front Immunol) 100 cases of phage therapy (Nat Micro) Synthetic biology potential of bacteriophages (Nat Micro) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

References Circulation. 2023.Oct 17;148(16):1231-1249. Int J Mol Sci . 2019. Oct 11;20(20):5028. Front Immunol. 2019; 10: 1706 Mastin, T. 1967 "How do you Feel" [Jefferson Airplane]. Surrealistic Pillow.lp. https://youtu.be/iWUa-rKT-oY?si=1M9496MbDUBGuj0A Hunter, Garcia, Kreutzman. 1975. "Franklin's Tower" [ Grateful Dead. Blues for Alah].lp. https://youtu.be/55TOIJxKc74?si=2wiiTKbWjw5LQvxF Haydn, FJ. 1790. String Quartet in D Major, Op. 64 No. 5 https://youtu.be/vNN_Kbuf7_U?si=KSfUc226hIIAmcy- --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Nat Rev Gastroenterol Hepatol. 2022 Jun;19(6):351-366 Drugs. 2016 Jul;76(11):1067-79. Front Immunol. 2021; 12: 613591 J Appl Microbiol. 2009. Jun;106(6):1908-18 Exp Cell Res. 2015 May 1; 333(2): 195–200. Mediators Inflamm. 2017; 2017: 4806541. Parsons, G. McQuinn,R. 1971. Pale Blue [ Byrds] Byrdmaniax lp. https://youtu.be/Mh3J7GqrdzY?si=Kp0XfrwPtSi4vY6q Baker, G. 1967. "Blue Condition" [Cream]. Disraeli Gears lp. https://youtu.be/bjQjEyJwPpg?si=70Nye1AGPWsgG0hs Strauss, J.(II). 1866 "An der schönen blauen Donau", Op. 314 https://youtu.be/fHzhDKwYP2s?si=umxkaYC6nRvikezX --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Front Immunol. 2019; 10: 1309 Immunity. 2018 Sep 18; 49(3):413–426.e5. Front Immunol. 2020; 11: 621733 Infect Immun. 2013 Dec; 81(12): 4478–4489. Immunity. 2023 Nov 14;56(11):2523-2541.e8. Harrison, G. 1969. "Here Comes the Sun" Abbey Road Lp. Beatles https://youtu.be/GKdl-GCsNJ0?si=xUqwi3Q7Ne694ruD Mozart, WA. 1775. Violin Concerto No.3 in G major, K. 216 https://youtu.be/j7Z6gouAVCc?si=xVwtNKAWDEDdtKMV Parsons, G. 1965 "Brass Buttons" Poco: Crazy Eyes Lp. https://youtu.be/CpFytplzLhI?si=vw08Gut3E-otgA9x --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Every year between Halloween and New Years my relationship with sugar gets tested.  This relationship has grown and evolved over the years, but I still find this time challenging.  Anyone else?  I know I'm not alone because we are literally wired to seek out the sweet taste and industrialization has made it so that we can find it everywhere. In this episode:The Ayurvedic perspective of the "sweet taste"How humans have evolved to seek out the sweet tasteHow a high sugar diet rewires the brain to be less able to resist sugarHow sugar affects the brainThe relationship between sugar, the  immune system and autoimmune disease Ways to protect your brain from the effects of sugar and find other sweetness in your lifeRelated Episodes:Episode 2:  The Lens of AyurvedaEpisode 10:   Kapha, the Sweet OneReferences:University of Würzburg. (2022, March 22). How sugar promotes inflammation. ScienceDaily. Retrieved January 3, 2024 from www.sciencedaily.com/releases/2022/03/220322122836.htmMa X, Nan F, Liang H, Shu P, Fan X, Song X, Hou Y, Zhang D. Excessive intake of sugar: An accomplice of inflammation. Front Immunol. 2022 Aug 31;13:988481. doi: 10.3389/fimmu.2022.988481. PMID: 36119103; PMCID: PMC9471313.Reichelt, A. (n.d.). A Neuroscientist Explains What Sugar Really Does to Our Brains. Science Alert. https://www.sciencealert.com/research-shows-sugar-can-change-your-brain-here-s-howFuhrman, J., MD (n.d.). Negative Effects of Sugar on the Brain. VeryWell Mind. https://www.verywellmind.com/how-sugar-affects-the-brain-4065218Find me at www.nourishednervoussystem.comand @nourishednervoussytem on Instagram

References Front. Immunol., 21 August 2019 Sec. Cancer Immunity and Immunotherapy Volume 10 Front Immunol. 2021; 12: 640869 PLoS One. 2014; 9(2): e87523 Vivaldi, A. 1719. "L 'inverno". https://youtu.be/pCqO-0339k0?si=k5xtuT8x7SfJeLok --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Ann. Review of Pathological Mechanisms of Disease2010.5:99-118. Nature 2013 Jul 4;499(7456):97-101. Front Immunol. 2018; 9: 476 Cells. 2021 Jun; 10(6): 1332 Nat Rev Gastroenterol Hepatol (2023). https://doi.org/10.1038/s41575-023-00846-4 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Front Immunol. 2022; 13: 950536. Inflamm Res. 2018 Oct;67(10):813-828 Mol Biol Rep. 2023; 50(8): 6963–6974. Front Immunol. 2023; 14: 1151166 Dr Guerra: Graduate biochemistry lecture archive Schubert.F. 1827.December.Impromptu #3 in G flat major performed by Khatia Buniatishvili https://youtu.be/LUp2u9wI1fY?si=hhiUmiyXyQ78Qtaw and "Questions" Manfred Mann 1976. https://youtu.be/qvvstrKLvts?si=-I8bGmB2oC3FpPLw --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

What is silica? How does it impact your risk of developing autoimmunity if you inhale it, inject it or even snort it up your nose? Listen and find out! ·       Intro 0:12 ·       In the previous episodes 0:28 ·       The Ajax incident of 1979 1:15 ·       Silica and its association with autoimmune disease 4:11 ·       The history of silica and the health risks 5:21 ·       Rheumatoid scleroderma, etc. 8:14 ·       Cardiff pneumoconiosis medical panel 9:49 ·       Databases 12:51 ·       Silica exposure and the development of serologies 15:02 ·       What would happen if you injected silica into the veins? 16:51 ·       Anca vasculitis 18:33 ·       Thanks for listening 23:23 Disclosures: Brown reports no relevant financial disclosures. We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Blanc PD, et al. Am J Med. 2015;doi:10.1016/j.amjmed.2015.05.001. Boudigaard SH, et al. Int J Epidemiol. 2021;doi:10.1093/ije/dyaa287. Conrad K, et al. Lupus. 1996;doi:10.1177/096120339600500112. Hoy RF, et al. Allergy. 2020;doi:10.111/all.14202. Klockars M, et al. Br Med J (Clin Res Ed). 1987;doi:10.1136/bmj.294.6578.997. Park CG, et al. Environ Health Perspect. 1999;doi:10.1289/ehp.99107s5793. Pollard KM. Front Immunol. 2016;doi:10.3389/fimmu.2016.00097.  

References Cream 1968 Wheels of Fire J Neuroinflammation. 2019; 16: 34. Front Immunol. 2019; 10: 345. Cell Metabolism 2023. Volume 35 Issue 4. 601-619.e10 Sci Signal. 2017 Jan 31; 10(464):eaaf7478 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Description: An immersive reading of Gitanjali 8 by Rabindranath Tagore with reflection on healthful dust, allergies, shared decision making, white coats and scrubs.  Website:https://anauscultation.wordpress.com/ Work:Gitanjali 8 by Rabindranath TagoreThe child who is decked with prince's robes and who has jewelled chains round his neck loses all pleasure in his play; his dress hampers him at every step.In fear that it may be frayed, or stained with dust he keeps himself from the world, and is afraid even to move.Mother, it is no gain, thy bondage of finery, if it keep one shut off from the healthful dust of the earth, if it rob one of the right of entrance to the great fair of common human life.References: Gitanjali https://www.gutenberg.org/cache/epub/7164/pg7164-images.html  Rabindranath Tagore https://www.poetryfoundation.org/poets/rabindranath-tagore  Blumenthal-Barby J, Opel DJ, Dickert NW, Kramer DB, Tucker Edmonds B, Ladin K, Peek ME, Peppercorn J, Tilburt J. Potential Unintended Consequences Of Recent Shared Decision Making Policy Initiatives. Health Aff (Millwood). 2019 Nov;38(11):1876-1881.Lambrecht, B., Hammad, H. The immunology of the allergy epidemic and the hygiene hypothesis. Nat Immunol 18, 1076–1083 (2017).Pfefferle PI, Keber CU, Cohen RM, Garn H. The Hygiene Hypothesis - Learning From but Not Living in the Past. Front Immunol. 2021 Mar 16;12:635935.Haahtela T. A biodiversity hypothesis. Allergy. 2019 Aug;74(8):1445-1456.O'Donnell VR, Chinelatto LA, Rodrigues C, Hojaij FC. A brief history of medical uniforms: from ancient history to the COVID-19 time. Rev Col Bras Cir. 2020 Jun 8;47:e20202597.Sood, S. (2023, July 10). Fashion-based medicine: A history of western doctors' dress - hektoen internationalShefali Sood. Hektoen International - An online medical humanities journal. https://hekint.org/2023/07/10/fashion-based-medicine-a-history-of-western-doctors-dress/

In this episode, I revisit the topic of COVID19 and pulmonary rehab, with a focus on rehab for patients with Long COVID. I mention a number of resources and papers, listed below:   1.  Perumal R, Shunmugam L, Naidoo K et al. Long COVID: a review and proposed visualization of the complexity of long COVID. Front Immunol 2023; 14: 1117464. Accessed July 4, 2023 at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157068/   2.  Journal of Health Economics and Outcomes Research Blog. Economic Effects of Long COVID Even Larger Than We Thought. Published December 13, 2022. Accessed July 4, 2023 at https://jheor.org/post/1746-economic-effects-of-long-covid-even-larger-than-we-thought   3.  Barker-Davies RM, O'Sullivan O, Pumi Prathima Senaratne K, et al. The Stanford Hall consensus statement for post-COVID-19 rehabilitation. Br J Sports Med 2020; 949-59. Accessed July 4, 2023 at https://bjsm.bmj.com/content/bjsports/54/16/949.full.pdf   4.  Cochrane Rehabilitation. REH-COVER – Rapid Living Systematic Reviews. Accessed July 4, 2023 at https://rehabilitation.cochrane.org/covid-19/reh-cover-rapid-living-systematic-reviews   5.  Canadian Physiotherapy Association. Rehabilitation for Clients with Post COVID-19 Condition (Long COVID). Guidance for Canadian Rehabilitation and Exercise Professionals. Accessed July 4, 2023 at https://physiotherapy.ca/app/uploads/2022/08/long_covid_en-final-rev2.pdf   6.  World Health Organization. Clinical Management of COVID19: living guideline. V6.0. Accessed July 4, 2023 at https://app.magicapp.org/#/guideline/j1WBYn/section/j7A12z I welcome your feedback about the show or ideas for future episodes. You can contact me via the comments section here on the LungFIT website. If you listen to the LungFIT podcast on iTunes, please take a moment to review the show. Click here to be directed.

Sind die Inzidenzen von Krebserkrankungen bei Kinder während der Pandemie gestiegen oder wurden Kinder später diagnostiziert? Erste Befürchtungen haben sich zum Glück nicht bestätigt, kann Prof. Thomas Lehrnbecher, Leiter des Schwerpunktes Onkologie, Hämatologie und Hämostaseologie der Klinik für Kinder- und Jugendmedizin in Frankfurt, entwarnen. Möglich aber, dass hier noch nicht das letzte Wort gesprochen ist. Der Grundsatz „First, do no harm“ ließ die Behandler von krebskranken Kindern die Therapie zum Teil aussetzen, wenn sie COVID-positiv waren. Hören Sie in dieser spannenden Rückschau, welche Lehren wir für die Zukunft ziehen können – vor allem die, insgesamt genauer auf Kinder und Jugendliche zu blicken. Hilfreiche Informationen: ECIL 9 Leitlinien: Cesaro S, Ljungman P, Mikulska M et al. (2022) Recommendations for the management of COVID-19 in patients with haematological malignancies or haematopoietic cell transplantation, from the 2021 European Conference on Infections in Leukaemia (ECIL 9). Leukemia 36: 1467–1480. ECIL 9 Part 2. Revised Guidelines - Update on COVID 19 in Hematology-Oncology patients. 2022. https://www.ecil-leukaemia.com/en/resources/resources-ecil (aufgerufen 12. Februar 2023). Literatur: Mukkada S, Bhakta N, Chantada GL et al. (2021) Global characteristics and outcomes of SARS-CoV-2 infection in children and adolescents with cancer (GRCCC): a cohort study. Lancet Oncol 22: 1416–1426. Abu Shanap M, Sughayer M, Alsmadi O et al. (2022) Factors that predict severity of infection and seroconversion in immunocompromised children and adolescents with COVID-19 infection. Front Immunol 13: 919762. Heininger U, Laws H-J & Lehrnbecher T (2021) Impfen von Kindern und Jugendlichen bei Immundefizienz. Consilium Themenheft 02-2021, InfectoPharm Arzneimittel und Consilium GmbH, ISSN 2365-7618. Link zum Transkript: https://www.infectopharm.com/consilium/podcast/podcast-paediatrie/ Kontakte: Feedback zum Podcast? podcast@infectopharm.com Homepage zum Podcast: www.infectopharm.com/consilium/podcast/ Für Fachkreise: www.wissenwirkt.com und App „Wissen wirkt.“ für Android und iOS Homepage InfectoPharm: www.infectopharm.com Disclaimer: Der consilium – Pädiatrie-Podcast dient der neutralen medizinischen Information und Fortbildung für Ärzte. Für die Inhalte sind der Moderator und die Gäste verantwortlich, sie unterliegen dem wissenschaftlichen Wandel des Faches. Änderungen sind vorbehalten. Impressum: consilium ist eine Marke von InfectoPharm Arzneimittel und Consilium GmbH Von-Humboldt-Str. 1 64646 Heppenheim   Tel.: 06252 957000 Fax: 06252 958844 E-Mail: kontakt@infectopharm.com   Geschäftsführer: Philipp Zöller (Vors.), Michael Gilster, Dr. Markus Rudolph, Dr. Aldo Ammendola Registergericht: Darmstadt – HRB 24623 USt.-IdNr.: DE 172949642   Verantwortlich für den Inhalt: Dr. Markus Rudolph

References Guerra Biochemistry lecture archives Nat Metab. 2022 Sep;4(9):1202-1213 Mol Cell. 2008 May 23; 30(4): 403–414 J Clin Invest. 2016 Nov 1; 126(11):4361–4371. Front Immunol. 2021; 12: 746151. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

Bonusepisode om type I interferoner, interleukin 6 og CRP ved SLE og andre bindevevssykdommer.Omtalte artikler: Enocsson et al. Front Immunol. 2021. Enocsson et al. J. Clin Med. 2021.Første sesong av podcasten er finansiert gjennom et stipend fra Norsk revmatologisk forening. Hosted on Acast. See acast.com/privacy for more information.

Primary reference: Suhre K, Sarwath H, Engelke R, Sohail MU, Cho SJ, Whalen W, Alvarez-Mulett S, Krumsiek J, Choi AMK, Schmidt F. Identification of Robust Protein Associations With COVID-19 Disease Based on Five Clinical Studies. Front Immunol. 2022 12:781100. doi:10.3389/fimmu.2021.781100Dr. Karsten Suhre's Weill Cornell Medicine laboratory page: https://vivo.weill.cornell.edu/display/cwid-kas2049Leukemia Inhibitory Factor reference: Loriot Y, Marabelle A, Guégan JP, et al. Plasma proteomics identifies leukemia inhibitory factor (LIF) as a novel predictive biomarker of immune-checkpoint blockade resistance. Ann Oncol. 2021 32(11):1381-1390. doi:10.1016/j.annonc.2021.08.1748In case you were wondering, Proteomics in Proximity refers to the principle underlying Olink Proteomics assay technology called the Proximity Extension Assay (PEA), and more information about the assay and how it works can be found here.Would you like to subscribe to the podcast on your favorite player or app? You can do so here: Apple Podcasts: https://apple.co/3T0YbSm Spotify Podcasts: https://open.spotify.com/show/2sZ2wxOqI4b4vSngkajLs8?si=d957d55c8db046f7 Google Podcasts: https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy50cmFuc2lzdG9yLmZtL3Byb3Rlb21pY3MtaW4tcHJveGltaXR5 Amazon Music: https://music.amazon.com/podcasts/d97ace94-f02b-4b37-9532-799548ef2840 Podcast Addict: https://podcastaddict.com/podcast/4098296 Deezer: https://www.deezer.com/show/5178787 Player FM: https://player.fm/series/series-3396598

Contributor: Nick Hatch, MD Educational Pearls: In the setting of traumatic injury, tranexamic acid (TXA) is given to stabilize clots which minimizes bleeding and decreases risk of hemorrhagic shock   Current TXA dose for trauma is 1 g bolus followed by a 1 g infusion; both doses should be given within 3 hours from time of injury  Due to the split dose and narrow window, patients with complicated care, particularly if they require transfer may miss the infusion dose  Various smaller studies have shown that dosing 2 g initially or 2 g followed by a 1 g infusion produces the same patient outcomes and no additional harm  Receiving hospitals should strive to acquire accurate information regarding previous doses of TXA given and confirm timeline of injury    References Roberts I, Shakur H, Coats T, et al. The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health Technol Assess. 2013;17(10):1-79. doi:10.3310/hta17100   Ramirez RJ, Spinella PC, Bochicchio GV. Tranexamic Acid Update in Trauma. Crit Care Clin. 2017;33(1):85-99. doi:10.1016/j.ccc.2016.08.004   Spinella PC, Thomas KA, Turnbull IR, et al. The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial. Front Immunol. 2020;11:2085. Published 2020 Sep 8. doi:10.3389/fimmu.2020.02085   Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, & Erik Verzemnieks, MD   In an effort to promote diversity, equity, and inclusion in Emergency Medicine, The Emergency Medical Minute is proud to present our 2nd annual Diversity and Inclusion Award. We support increasing the representation of underrepresented groups in medicine and extend this award to individuals applying to emergency medicine residencies during the 2022-2023 cycle. For information on award eligibility and the application process, visit https://emergencymedicalminute.com/edi-award/ Donate to EMM today!

Pour accéder à l'intégralité de ce podcast et écouter chaque semaine un nouvel épisode du Quart d'Heure Véto, c'est très simple, il vous suffit de vous abonner en cliquant sur ce lien : https://m.audiomeans.fr/s/S-yUNSBZSR Leonie fingerhut et ses collaborateurs ont étudiés l'implication des pièges neutrophiliques extracellulaires (NET), un système initialement censé protéger l'organisme, sur la pathogénie des uvéites, ainsi que l'implication des leptospires dans ce phénomène auto-immun, où l'organisme se retourne contre lui-même. L'objectif de cette étude expérimentale menée principalement ex-vivo à partir de prélèvements biologiques, est d'étudier l'impact des NET chez les patients atteints d'uvéite récurrente équine (URE). Ils ont quantifié plusieurs marqueurs de ces pièges neutrophiliques (ADN libre extracellulaire, nucléosomes, histone H3 citrullinée, complexes histone-myéloperoxydases, interleukine-17, la cathélicidine 1 équine et l'activité DNase I), ainsi qu'un dosage et suivi des auto-anticorps anti-NET dans le sérum et le vitré des chevaux atteints d'URE, en essayant de corréler ces données avec le stade et la sévérité de la maladie (scores ERU et infection ou non par Leptospira). Notes et références Article L.Fingerhut - Ex Vivo and In Vitro Analysis Identify a Detrimental Impact of Neutrophil Extracellular Traps on Eye Structures in Equine Recurrent Uveitis - 2022 Front Immunol. 2022 Feb 10;13:830871. (OPEN ACESS) : https://www.frontiersin.org/articles/10.3389/fimmu.2022.830871/full Retrouvez toute la synthèse sur la Fiche Podcast : https://audmns.com/QVNfNRj Pour nous suivre : 1. Abonnez-vous à notre chaine pour profiter de l'intégralité des épisodes : Le Quart d'Heure Véto : décrypte et résume en moins de 15 min un article de biblio véto - Sur abonnement uniquement, Le Véto du Mois : Partagez le temps d'une interview l'expérience de vétérinaires emblématiques de notre milieu, des rencontres conviviales, comme si nous étions dans votre salon au coin du feu. Podcasts bonus au fil des inspirations... 2. Le Scope Nous partageons avec vous nos dernières découvertes, inspirations, pistes de réflexion, nouveautés… À découvrir et utiliser dès maintenant, TOUT DE SUITE, dans votre quotidien de vétérinaire, de manager, de vie personnelle, de chef d'entreprise… Et tout cela en moins de 5 minutes top chrono un à 2 mardis par mois ! Je souhaite recevoir mon Scope : https://vetmasterclass.com/lescope/ 3. Contactez-nous, suivez-nous et donnez nous votre avis ! Des sujets que vous souhaiteriez approfondir, des références à partager, ou nous faire part de vos feed-backs : Abonnez-vous à notre chaine, donnez nous des étoiles, un commentaire et partagez autour de vous ! Sur notre site : https://vetmasterclass.com/ Sur Facebook : https://www.facebook.com/VmHorse Sur Instagram : https://www.instagram.com/vetmasterclass/ Sur YouTube : https://www.youtube.com/channel/UC18ovcWk9e-mFiTL34OQ03g Sur Linkedin : https://www.linkedin.com/company/vetmasterclass-horse/about/ Belle journée à tous, Et continuez à vivre votre métier avec Passion !

References Dr Guerra's Immunology lectures Am J Gastroenterol. 2004 Nov;99(11):2147-9. Front Immunol. 2019 Jun 7;10:1309 Nat Rev Gastroenterol Hepatol. 2019 Dec 9 Immunity Volume 55 Issue 8 Pages 1370-1385.e8 (August 2022) DOI: 10.1016/j.immuni.2022.06.007 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

*The information in this podcast is intended for Healthcare Practitioners. Endometriosis is a common and debilitating condition that has proven difficult to treat. In this episode, Sun-Wei Guo, a geneticist turned Professor of Gynaecology, reveals his eye-opening research into the pathophysiology of endometriosis. Sun Wei explains how the theory of retrograde flow in endometriosis is necessary but not sufficient to explain the progression of the disease. Prof Guo explains that endometriotic lesions are wounds undergoing repeated tissue injury and repair (ReTIAR). Sun Wei further describes how surprising mediators in the endometriotic microenvironment are responsible for the incomplete repair process that leads to the cellular hallmarks of endometriosis. Hear about Prof Guo's preliminary work on herbal constituents and electrical stimulation that are generating encouraging results in endometriosis. Listen in to discover new non-hormonal targets that can be considered to combat this terrible affliction. Professor Guo received his Ph.D. from the University of Washington and had subsequent stints at University of Michigan and the Medical College of Wisconsin. Since 2010 Sun Wei has been a Professor at Shanghai OB/GYN Hospital, Fudan University and an adjunct professor at Department of Obstetrics, Gynecology and Reproductive Biology at Michigan State University College of Human Medicine. Prof Guo has been an Associated Editor of several reproduction journals and a board member of several endometriosis societies, including member of the Board of Trustees of the World Endometriosis Society (WES). Links: Guo SW. Fibrogenesis resulting from cyclic bleeding: the Holy Grail of the natural history of ectopic endometrium. Hum Reprod. 2018 Mar 1;33(3):353-356. https://pubmed.ncbi.nlm.nih.gov/29420711/ Xiao F, Liu X, Guo SW. Platelets and Regulatory T Cells May Induce a Type 2 Immunity That Is Conducive to the Progression and Fibrogenesis of Endometriosis. Front Immunol. 2020 Dec 14;11:610963. https://pubmed.ncbi.nlm.nih.gov/33381124/ Yan D, Liu X, Guo SW. Neuropeptides Substance P and Calcitonin Gene Related Peptide Accelerate the Development and Fibrogenesis of Endometriosis. Sci Rep. 2019 Feb 25;9(1):2698. https://pubmed.ncbi.nlm.nih.gov/30804432/ Huang S, Xiao F, Guo SW, Zhang T. Tetramethylpyrazine Retards the Progression and Fibrogenesis of Endometriosis. Reprod Sci. 2022 Apr;29(4):1170-1187. https://pubmed.ncbi.nlm.nih.gov/35099777/ Hao M, Liu X, Rong P, Li S, Guo SW. Reduced vagal tone in women with endometriosis and auricular vagus nerve stimulation as a potential therapeutic approach. Sci Rep. 2021 Jan 14;11(1):1345. https://pubmed.ncbi.nlm.nih.gov/33446725/ Hao M, Liu X, Guo SW. Activation of α7 nicotinic acetylcholine receptor retards the development of endometriosis. Reprod Biol Endocrinol. 2022 Jun 4;20(1):85. https://pubmed.ncbi.nlm.nih.gov/35658970/

What if you could take a pill that reversed aging? Well, David Sinclair, a biologist and Harvard genetics professor, had high hopes when he discovered resveratrol, a molecule found in grapes could help reverse the effects of aging like inflammation and cell growth. He claimed one day there would be a pill people could take that would solve all of our aging problems. The media had a field day with his findings and soon resveratrol made its way into wellness as the new fad food. Better yet, you could find resveratrol in wine! But what happens when research studies go wrong? When the findings aren't always what they seem? The story of resveratrol is a great example of trusting the data too soon, before it's replicated over and over by other scientist. Today's story is about one scientist who got too ahead of himself which led to criticism and conflicts of interest.....all in the name of aging and fame. Resources: https://www.wsj.com/articles/BL-HEB-3860 Gupta SC, Kunnumakkara AB, Aggarwal S, Aggarwal BB. Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases. Front Immunol. 2018;9:2160. Published 2018 Sep 27. doi:10.3389/fimmu.2018.02160 Brenjian S, Moini A, Yamini N, et al. Resveratrol treatment in patients with polycystic ovary syndrome decreased pro-inflammatory and endoplasmic reticulum stress markers. Am J Reprod Immunol. 2020;83(1):e13186. doi:10.1111/aji.13186 Martins L.A.M., Coelho B.P., Behr G., Pettenuzzo L.F., Souza I.C.C., Moreira J.C.F., Borojevic R., Gottfried C., Guma F.C.R. Resveratrol induces pro-oxidant effects and time-dependent resistance to cytotoxicity in activated hepatic stellate cells. Cell Biochem. Biophys. 2014;68:247–257. doi: 10.1007/s12013-013-9703-8. Salehi B, Mishra AP, Nigam M, et al. Resveratrol: A Double-Edged Sword in Health Benefits. Biomedicines. 2018;6(3):91. Published 2018 Sep 9. doi:10.3390/biomedicines6030091

Cast:Priya YenebereZac CerraChristel Wekon-KemeniMo IbrahimReferencesCooper, DKC. “A Brief History of Cross-Species Organ Transplantation.” Proceedings - Baylor University. Medical Center 25.1 (2012): 49–57. Web. DOI:10.1080/08998280.2012.11928783Roux FA, Saï P, Deschamps JY. Xenotransfusions, past and present. Xenotransplantation. 2007;14(3):208-216. DOI:10.1111/j.1399-3089.2007.00404.xDenner J. Porcine endogenous retroviruses (PERVs) and xenotransplantation: screening for transmission in several clinical trials and in experimental models using non-human primates. Ann Transplant. 2003;8(3):39-48. https://doi.org/10.1186/s12977-018-0411-8Wijkstrom M, Iwase H, Paris W, Hara H, Ezzelarab M, Cooper DK. Renal xenotransplantation: experimental progress and clinical prospects. Kidney Int. 2017;91(4):790-796. DOI: 10.1016/j.kint.2016.08.035Soin B, Smith KG, Zaidi A, et al. Physiological aspects of pig-to-primate renal xenotransplantation. Kidney Int. 2001;60(4):1592-1597. DOI: 10.1046/j.1523-1755.2001.00973.xIwase H, Liu H, Wijkstrom M, et al. Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date. Xenotransplantation. 2015;22(4):302-309. DOI: 10.1111/xen.12174Cooper DKC, Wijkstrom M, Hariharan S, et al. Selection of Patients for Initial Clinical Trials of Solid Organ Xenotransplantation. Transplantation. 2017;101(7):1551-1558. DOI: 10.1097/TP.0000000000001582Fishman JA. Infectious disease risks in xenotransplantation. Am J Transplant. 2018;18(8):1857-1864. DOI:10.1111/ajt.14725Rosner F. Pig organs for transplantation into humans: a Jewish view. Mt Sinai J Med. 1999;66(5-6):314-319.Mansour T. Azhar issues fatwa allowing transplant of pigs' kidneys. The New Arab. https://english.alaraby.co.uk/news/azhar-issues-fatwa-allowing-transplant-pigs-kidneys. Accessed July 3, 2022. Lu T, Yang B, Wang R, Qin C. Xenotransplantation: Current Status in Preclinical Research. Front Immunol. 2020;10:3060. Published 2020 Jan 23. DOI:10.3389/fimmu.2019.03060Carrier AN, Verma A, Mohiuddin M, et al. Xenotransplantation: A New Era. Front Immunol. 2022;13:900594. Published 2022 Jun 9. DOI:10.3389/fimmu.2022.900594

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.   In today's episode, our guest Dr Bryan G Fry, aka Venom Doc, will make us enter his world and understand how venom interact with coagulation and how they can prove useful for assay or drug design & development     Literature sources: Fry BG, Roelants K, Champagne DE, Scheib H, Tyndall JD, King GF, Nevalainen TJ, Norman JA, Lewis RJ, Norton RS, Renjifo C, de la Vega RC. The toxinogenomic multiverse: convergent recruitment of proteins into animal venoms. Annu Rev Genomics Hum Genet. 2009, 10: 483-511. Bittenbinder, M. A., C. N. Zdenek, B. Op den Brouw, N. J. Youngman, J. S. Dobson, A. Naude, F. J. Vonk and B. G. Fry (2018). "Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)." Toxins (Basel) 10(12): 516. Chowdhury, A., M. R. Lewin, C. N. Zdenek, R. Carter and B. G. Fry (2021a). "The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (Naja Species) Venoms." Front Immunol 12: 752442. Seneci, L., C. N. Zdenek, A. Chowdhury, C. F. B. Rodrigues, E. Neri-Castro, M. Benard-Valle, A. Alagon and B. G. Fry (2021). "A Clot Twist: Extreme Variation in Coagulotoxicity Mechanisms in Mexican Neotropical Rattlesnake Venoms." Front Immunol 12: 612846. Chowdhury, A., C. N. Zdenek, J. S. Dobson, L. A. Bourke, R. Soria and B. G. Fry (2021b). "Clinical implications of differential procoagulant toxicity of the palearctic viperid genus Macrovipera, and the relative neutralization efficacy of antivenoms and enzyme inhibitors." Toxicol Lett 340: 77-88. Chowdhury, A., C. N. Zdenek, M. R. Lewin, R. Carter, T. Jagar, E. Ostanek, H. Harjen, M. Aldridge, R. Soria, G. Haw and B. G. Fry (2021). "Venom-Induced Blood Disturbances by Palearctic Viperid Snakes, and Their Relative Neutralization by Antivenoms and Enzyme-Inhibitors." Frontiers in Immunology 12: 2251. Zdenek, C. N., B. O. den Brouw, D. Dashevsky, A. Gloria, N. Youngman, E. Watson, P. Green, C. Hay, N. Dunstan, L. Allen and B. G. Fry (2019a). "Clinical implications of convergent procoagulant toxicity and differential antivenom efficacy in Australian elapid snake venoms." Toxicol Lett 316: 171-182. Zdenek, C. N., C. Hay, K. Arbuckle, T. N. W. Jackson, M. H. A. Bos, B. Op den Brouw, J. Debono, L. Allen, N. Dunstan, T. Morley, M. Herrera, J. M. Gutierrez, D. J. Williams and B. G. Fry (2019b). "Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom." Toxicol In Vitro 58: 97-109. Sousa, L. F., C. A. Nicolau, P. S. Peixoto, J. L. Bernardoni, S. S. Oliveira, J. A. Portes-Junior, R. H. Mourao, I. Lima-dos-Santos, I. S. Sano-Martins, H. M. Chalkidis, R. H. Valente and A. M. Moura-da-Silva (2013). "Comparison of phylogeny, venom composition and neutralization by antivenom in diverse species of bothrops complex." PLoS Negl Trop Dis 7(9): e2442. Rogalski, A., C. Soerensen, B. Op den Brouw, C. Lister, D. Dashevsky, K. Arbuckle, A. Gloria, C. N. Zdenek, N. R. Casewell, J. M. Gutierrez, W. Wuster, S. A. Ali, P. Masci, P. Rowley, N. Frank and B. G. Fry (2017). "Differential procoagulant effects of saw-scaled viper (Serpentes: Viperidae: Echis) snake venoms on human plasma and the narrow taxonomic ranges of antivenom efficacies." Toxicol Lett 280: 159-170. Youngman, N. J., J. Llinas and B. G. Fry (2021). "Evidence for Resistance to Coagulotoxic Effects of Australian Elapid Snake Venoms by Sympatric Prey (Blue Tongue Skinks) but Not by Predators (Monitor Lizards)." Toxins (Basel) 13(9).   Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

References Nat Cell Biol. 2019 Mar; 21(3): 397–407 CELL Volume 126, Issue 3, 11 August 2006, Pages 503-514 Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55 Int J Biol Sci. 2015; 11(11): 1272–1280 Sci Signal. 2017 Jan 31; 10(464): eaaf7478. Front Immunol. 2019; 10: 345. J Neuroinflammation. 2019; 16: 34. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

Das Komplementsystem ist als Teil des angeborenen humoralen Immunsystems eines unserer wichtigsten Abwehrmechanismen gegen zelluläre Antigene.1 Aber nicht immer macht das Komplementsystem was es soll und verschiedene Erkrankungen können die Folge sein. In diesem Podcast erfahren Sie das Wichtigste über diesen komplexen Bereich der Immunologie, einfach und anschaulich dargestellt. Gast: PD Dr. Christoph Schmidt, Institut für Naturheilkunde und Klinische Pharmakologie am Universitätsklinikum Ulm. Moderator: Prof. Dr. med. Martin Grond, Chefarzt der Neurologie im Kreisklinikum Siegen 1. Merle NS et al. Complement system part II: role in immunity. Front Immunol. 2015 May 26;6:257. doi: 10.3389/fimmu.2015.00257. DE/UNB-U/0016

Trigger warning right away: Masks. Yes we are talking masks today and understand that none of what I share with you today is personal opinion but from peer reviewed studies and actual science. This episode isn't meant to shame either "side" whether you choose to wear a mask or not. This is strictly for those who want to be informed to make the best decision for themselves.   Time Stamps:   (0:43) Making Observations and Polarity (2:42) Getting Into Controversial Topics (5:30) Masks (7:51) History of Masks (12:50) The Media in 1918 and Masks (15:15) Tuberculosis (23:10) Masks in Hospital Setting (24:32) Mask Wearing Side Effects (31:45) Autonomy ---------------------------- Resources:   1. Cantwell A. Cancer and most diseases are caused by BACTERIA: Bechamp's microzymas & human disease. March 17, 2017. https://rense.com/general96/bechamps.htm/. 2. Review of Béchamp A, The Blood and Its Third Element. https://www.goodreads.com/book/show/2213391.The_Blood_and_Its_Third_Element. 3. Young RO. Who had their finger on the magic of life—Antoine Bechamp or Louis Pasteur? Int J Vaccines Vaccin 2016;2(5):00047. 4. Williams LL. Radical Medicine: Profound Intervention in a Profoundly Toxic Age (2nd ed.). San Francisco, CA: International Medical Arts Publishing, 2007-2008, p. 34. 5. “Honoring Antoine Béchamp: The gentle giant of science & medicine.” https://oawhealth.com/article/honoring-antoine-bechamp-the-gentle-giant-of-science-medicine/. 6. Appleton N. Why Louis Pasteur's germ theory is a curse. http://whale.to/w/appleton1.html. 7. Cox L, Peck P. The top 10 medical advances of the decade—from genome to hormones, doctors pick the top medical advances of the decade. MedPage Today, Dec. 17, 2009. 8. Bethell CD, Kogan MD, Strickland BB et al. A national and state profile of leading health problems and health care quality for US children: key insurance disparities and across-state variations. Acad Pediatr 2011;11(3 Suppl):S22-S33. 9. “Highlights: 2016 millennials survey.” https://www.transamericacenterforhealthstudies.org/health-careresearch/2016-millennials-survey-highlights. 10. Chapel JM, Ritchey MD, Zhang D et al. Prevalence and medical costs of chronic diseases among adult Medicaid beneficiaries. Am J Prev Med 2017;53(6 Suppl 2):S143-S154. 11. GBD 2017 Child and Adolescent Health Collaborators, Reiner RC Jr., Olsen HE, et al. Diseases, injuries, and risk factors in child and adolescent health, 1990 to 2017: findings from the Global Burden of Diseases, Injuries, and Risk Factors 2017 study. JAMA Pediatr 2019 Apr 29:e190337. 12. Aldhous P. Why Americans are so damn unhealthy, in 4 shocking charts. BuzzFeed News, May 24, 2017. 13. https://arizonaenergy.org/BodyEnergy/antoine_bechamp.htm. 14. Smith KA. Louis Pasteur, the father of immunology? Front Immunol 2012;3:68. 15. Raines K. Pasteur vs Béchamp: The germ theory debate. The Vaccine Reaction, Feb. 6, 2018. 16. “Emergence of pharmaceutical science and industry: 1870-1930.” https://pubsapp.acs.org/cen/coverstory/83/8325/8325emergence.html. 17. Hume ED. Béchamp or Pasteur? A Lost Chapter in the History of Biology. http://www.mnwelldir.org/docs/history/biographies/Bechamp-or-Pasteur.pdf. 18. “Antoine Béchamp.” http://www.pnf.org/compendium/Antoine_Bechamp.pdf. 19. “Zyme.” https://en.wiktionary.org/wiki/zyme. 20. “History – Antoine Béchamp.” https://www.brmi.online/antoine-bechamp. 21. Lee H-S, Lee B-C, Kang D-I. Spontaneous self-assembly of DNA fragments into nucleus-like structures from yolk granules of fertilized chicken eggs: Antoine Béchamp meets Bong Han Kim via Olga Lepeshinskaya. Micron 2013;51:54-59. 22. François P, Guyot A, Jean D et al. [Complications of varicella as a function of the terrain. Apropos of 103 cases.] [Article in French] Pediatrie 1985;40(2):99-106. 23. Ventola CL. The antibiotic resistance crisis. Part 1: causes and threats. P T 2015;40(4):277-83. 24. Schiavone R. Drug-resistant superbug confirmed in California. Patch, May 7, 2019. 25. Rappuoli R, Bloom DE, Black S. Deploy vaccines to fight superbugs. Nature, Dec. 12, 2017. 26. De Gregorio E, Rappuoli R. From empiricism to rational design: a personal perspective of the evolution of vaccine development. Nat Rev Immunol 2014;14(7):505-14. 27. Children's Health Defense. Failure to vaccinate or vaccine failure: what is driving disease outbreaks? Mar. 6, 2019. https://childrenshealthdefense.org/news/failure-to-vaccinate-or-vaccine-failure-what-is-driving-disease-outbreaks/. 28. Cherry JD. The 112-year odyssey of pertussis and pertussis vaccines—mistakes made and implications for the future. J Pediatric Infect Dis Soc 2019 Feb. 22. 29. Lapidot R, Gill CJ. The pertussis resurgence: putting together the pieces of the puzzle. Top Dis Travel Med Vaccines 2016;2:26. 30. Cowling BJ, Fang VJ, Nishiura H et al. Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine. Clin Infect Dis 2012;54(12):1778-83. 31. Flu vaccine paradox adds to public health debate. CBS News, Jan. 16, 2015. 32. https://www.fda.gov/media/74350/download. 33. Brewer NT, Moss JL. Dangers of vaccine refusal near the herd immunity threshold: a modelling study. Lancet Infect Dis 2015;15(8):922-6. 34. Kennedy, Jr. RF. MMR vaccine's poison pill: mumps after puberty, reduced testosterone and sperm counts. Children's Health Defense, Apr. 4, 2019. https://childrenshealthdefense.org/news/vaccines/mmr-vaccines-poison-pill-mumps-after-puberty-reduced-testosterone-and-sperm-counts/. 35. https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/b/excipient-table-2.pdf. 36. Bush Z. Disruption of the gut microbiome and gut permeability as ground zero for the nutrition-related epidemics of the developed world. Presented at the 13th International Congress on Advances in Natural Medicines, Neutraceuticals & Neurocognition, Rome, Italy, July 27-28, 2017. 37. Lange K, Buerger M, Stallmach A et al. Effects of antibiotics on gut microbiota. Dig Dis 2016;34(3):260-8. 38. Myers JP, Antoniou MN, Blumberg B et al. Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environ Health 2016;15:19. 39. Thomas S, Izard J, Walsh E et al. The host microbiome regulates and maintains human health: a primer and perspective for non-microbiologists. Cancer Res 2017;77(8):1793-1812. 40. Zumia A, Maeurer M, Host-Directed Therapies Network (HDT-NET) Consortium. Host-directed therapies for tackling multi-drug resistant tuberculosis: learning from the Pasteur-Bechamp debates. Clin Infect Dis 2015;61(9):1432-8. ---------------------------- Follow Me on Instagram! @tayloredwellbeing - https://www.instagram.com/tayloredwellbeing/ ---------------------------- Click Here to Apply to Work with Me or visit taylorsappington.com/application