Podcasts about gbd

  • 69PODCASTS
  • 146EPISODES
  • 51mAVG DURATION
  • 1EPISODE EVERY OTHER WEEK
  • Jun 2, 2025LATEST

POPULARITY

20172018201920202021202220232024


Best podcasts about gbd

Latest podcast episodes about gbd

The Pyllars Podcast with Dylan Bowman
Alex King | The Story of Terignōta

The Pyllars Podcast with Dylan Bowman

Play Episode Listen Later Jun 2, 2025 74:06


Today's episode is a crosscast with our other show, Second Nature. If you enjoy this type of content, search and subscribe to the show on your favorite podcast player or on YouTube.   Alex King launched his brand Terignōta less than a year ago, showing the industry that it is possible to deliver high quality running apparel without breaking the bank. In this extremely transparent conversation, Alex shares all of the details of the business. As a first-time founder, Alex shares all of the lessons he's learned, as well as his plans for the future of Terignōta. Show Notes: Terignōta: https://terignota.com/ Trailmix Article: https://wearetrailmix.substack.com/p/what-if-running-apparel-was-cheaper Warby Parker HIBT Episode: https://www.npr.org/2018/03/26/586048422/warby-parker-dave-gilboa-neil-blumenthal Terignōta x Abigail West: https://terignota.com/products/abigail-west-x-crest-cap Shopify Loan Program: https://www.shopify.com/capital Outside Buyer's Guide: https://www.outsideonline.com/outdoor-gear/clothing-apparel/best-running-shirts-for-men/ Brand, Product, Content: Gates $100k Prize: https://go.gates.com/GBD-100k-BELTED-PURSE.html Andy Irons Film: https://www.youtube.com/watch?v=GJWIPRvtAHk HY.Q: https://www.drinkhyq.com/ Join us on LinkedIn: https://www.linkedin.com/company/second-nature-media Meet us on Slack: https://www.launchpass.com/second-nature Follow us on Instagram: https://www.instagram.com/secondnature.media Subscribe to our newsletter: https://www.secondnature.media Subscribe to the YouTube channel: https://www.youtube.com/@secondnaturemedia

Second Nature
The Story of Terignōta

Second Nature

Play Episode Listen Later May 30, 2025 68:23


Alex King launched his brand Terignōta less than a year ago, showing the industry that it is possible to deliver high quality running apparel without breaking the bank. In this extremely transparent conversation, Alex shares all of the details of the business. As a first-time founder, Alex shares all of the lessons he's learned, as well as his plans for the future of Terignōta. Show Notes: Terignōta: https://terignota.com/ Trailmix Article: https://wearetrailmix.substack.com/p/what-if-running-apparel-was-cheaper Warby Parker HIBT Episode: https://www.npr.org/2018/03/26/586048422/warby-parker-dave-gilboa-neil-blumenthal Terignōta x Abigail West: https://terignota.com/products/abigail-west-x-crest-cap Shopify Loan Program: https://www.shopify.com/capital Outside Buyer's Guide: https://www.outsideonline.com/outdoor-gear/clothing-apparel/best-running-shirts-for-men/ Brand, Product, Content: Gates $100k Prize: https://go.gates.com/GBD-100k-BELTED-PURSE.html Andy Irons Film: https://www.youtube.com/watch?v=GJWIPRvtAHk HY.Q: https://www.drinkhyq.com/ Join us on LinkedIn: https://www.linkedin.com/company/second-nature-media Meet us on Slack: https://www.launchpass.com/second-nature Follow us on Instagram: https://www.instagram.com/secondnature.media Subscribe to our newsletter: https://www.secondnature.media Subscribe to the YouTube channel: https://www.youtube.com/@secondnaturemedia

In conversation with...
Marie Ng on public health in ASEAN

In conversation with...

Play Episode Listen Later May 27, 2025 15:47


Marie Ng speaks to Hui Wu about four Global Burden of Disease studies on cardiovascular diseases, smoking, mental health and injury in the ASEAN to inform public health priorities setting and policy planning.You can read the four GBD papers here:Smoking: https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(24)00326-8/fulltext?dgcid=buzzsprout_icw_podcast_May_25_lanpubInjury burden: https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00069-6/fulltext?dgcid=buzzsprout_icw_podcast_May_25_lanpubCardiovascular disease: https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00087-8/fulltext?dgcid=buzzsprout_icw_podcast_May_25_lanpubMental disorders: https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00098-2/fulltext?dgcid=buzzsprout_icw_podcast_May_25_lanpubContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

Radio Crystal Blue
Radio Crystal Blue 4/30/25 part 1

Radio Crystal Blue

Play Episode Listen Later May 1, 2025 135:49


Reverend Freakchild "Om Mani Padme Hum" & "I Can't Be Satisfied" - The Bodhisattva Blues www-reverendfreakchild.org Reverend TJ McGlinchey "Hey Baby" - There Was A Time www.revtj.com Reverend Raven & The Chain-Smokin' Altar Boys "Creature Of Habit" - My Life (Twentieth Anniversary) www.reverendraven.com Reverend Shawn Amos "Boogie" - The Reverend Shawn Amos Love You www.shawnamos.com Reverend Peyton's Big Damn Band "Are You Gonna Rise? (For LeVar)" www.bigdamnband.com **************************Kris Angelis "Brighter Blue" - That Song, Hope www.krisangelis.com Grace Morrison "Ghost Of It" - Maybe Modern www.gracemorrison.com Jann Klose "Love You The Most" - Surrender www.jannklose.com Bernadette Connors "White Magnolia" www.bernadetteconnors.com Alice Howe & Freebo "You've Been Away So Long" - Live www.alicehowe.com Shanna In A Dress "Everything & Nothing" - Robot www.shannainadress.comMeghan Cary "Sail Across The Water" - Singg Louder www.meghancary.com*************Push Puppets "This Whole Endeavor" - Tethered Together https://www.pushpuppets.net/Tim McBride & The Divide "Falling Away Again" - Off The Ground www.timmcbridemusic.com Box Elder "Origami Bats" www.boxelder.com The Bad Ups "Better Than You" - Life Of Sin The Human Rights "Roxham Road" - One People https://www.thehumanrights.ca/Feverjaw "The Physical Limit" www.feverjaw.com ***************Bone & Yarrow "Dragon" - s/t Dropsonic "So Long" - s/t https://www.facebook.com/dropsonicofficial/B-Movie "Marilyn Dreams" - Hidden Treasures www.b-movie.org GBD "I Can't Take It Anymore" www.gbdkc.comScott Yoder "Portrait Of Anneliese" https://www.scottmatthewyoder.com

Plant-Based Canada Podcast
Episode 98: Greener by Default with Katie Cantrell

Plant-Based Canada Podcast

Play Episode Listen Later Apr 15, 2025 34:39


In the latest episode of the Plant-Based Canada Podcast, we chat with Kati Cantrell. Katie is a social entrepreneur passionate about creating a healthy, sustainable, and just food system. As the founder of the New Roots Institute, Katie spent a decade leading food policy workshops at universities, government agencies, and Fortune 500 corporations.She is now utilizing her expertise to implement plant-based defaults in institutional foodservice as the CEO and Co-Founder of Greener by Default. The organization offers strategies to institutions that serve food about how to incorporate plant-based defaults, and use behavioural economics research to help people lean toward healthier choices.Katie holds a Bachelor's degree in psychology from UC Berkeley. Her work with GBD was recently featured in the New York Times, and she was chosen for Vox's Future Perfect 50 list of innovators, thinkers, and changemakers for 2024.ResourcesGreener by Default“We're being nudged to eat meat. What if the tables were turned?”Bonus PromotionCheck out University of Guelph's online Plant-Based Nutrition Certificate. Each 4-week course will guide you through essential plant-based topics including nutritional benefits, disease prevention, and environmental impacts. You can also customize your learning with unique courses such as Plant-Based Diets for Athletes and Implementing a Plant-Based Diet at Home. As the first university-level plant-based certificate in Canada, you'll explore current research, learn from leading industry experts, and join a community of like-minded people. Use our exclusive discount code PBC2025 to save 10% on all Plant-Based Nutrition Certificate courses. uoguel.ph/pbn.Support the show

We Want Them Infected Podcast
Misguided Theories & Missing Data: Revisiting the GBD's Legacy

We Want Them Infected Podcast

Play Episode Listen Later Mar 26, 2025 65:32


This episode critically examines In COVID's Wake by Princeton professors Steven M. and Francis Lee, focusing on their defense of the Great Barrington Declaration. Dr. Jonathan Howard and Wendy Orent argue that the authors downplay the catastrophic errors of the GBD architects, who pushed for herd immunity through mass infection while opposing vaccines, masks, and lockdowns.  The discussion highlights the disconnection between political science theorizing and real-world public health outcomes. Using Florida as a case study, they showcase the tragic failures of the GBD's approach, debunking the revisionist portrayal of its policies as reasonable or compassionate. The episode underscores the importance of accurately remembering the pandemic's scientific realities and human costs. Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

The Purple Reign Podcast
Don't leave me Murph!

The Purple Reign Podcast

Play Episode Listen Later Mar 17, 2025 51:59


In this episode, we share the collective disappointment over the opening round for the Dockers. Duck and Oz deep dive into the GBD, look forward to any potential changes this week and then delve into some quality listener questions. The only way is up from here, and the boys try to make some sense of the carnage of opening round. Hosted on Acast. See acast.com/privacy for more information.

This Week in Cardiology
Jan 10 2025 This Week in Cardiology

This Week in Cardiology

Play Episode Listen Later Jan 10, 2025 30:19


Alcohol and cancer, GLP-1 trial representativeness, diagnosing CAD, changing stroke rates in patients with AF, blanking periods after AF ablation are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Surgeon General Causes Hoopla Regarding ETOH Warning Dry January: Should Doctors Make It Year-Round? https://www.medscape.com/viewarticle/dry-january-should-doctors-make-it-year-round-2025a100009t Surgeon General Warning https://www.hhs.gov/about/news/2025/01/03/us-surgeon-general-issues-new-advisory-link-alcohol-cancer-risk.html GBD 2016 Collaboration Lancet https://doi.org/10.1016/S0140-6736(18)31310-2 RCT Voskobonik and colleagues https://www.nejm.org/doi/full/10.1056/NEJMoa1817591 Marcus and colleagues; UCSF https://pubmed.ncbi.nlm.nih.gov/33516710/ Review of ETOH AF https://doi.org/10.1016/j.jacc.2016.08.074 II. GLP-1 Agonists for Obesity –Trial vs Real World Generalizability of Trial Results https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2826335 HRS Document ICD http://dx.doi.org/10.1016/j.hrthm.2014.03.041 III. Stress Testing and CAD Severity Reynolds and colleagues. Observational ISCHEMIA Sub-analysis https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.123.013743 Foy Meta-analysis https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2655243 ISCHEMIA https://www.nejm.org/doi/full/10.1056/NEJMoa1915922 IV. Changing Stroke Rates with AF Teppo and colleagues. Finnish Study https://doi.org/10.1016/j.jacep.2024.10.029 Quinn and colleagues. https://www.ahajournals.org/doi/10.1161/circulationaha.116.024057 V. Patients' Lives Don't Pause for Blanking Periods Ruzieh and colleagues. https://doi.org/10.1016/j.ahjo.2024.100497 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

The Book of Murdoc
November with Austin pt 2

The Book of Murdoc

Play Episode Listen Later Nov 27, 2024 49:05


Recorded post-election, November 2024. Loose Monkeys. Austin didn't do a thing for the cause. Uzbekistan women who talk you into faking your death. GBD. Chimps aren't pets. Learning things about Austin! Nic Cage movies. Austin officially got old. "It's the funniest thing that's ever happened." Hosted on Acast. See acast.com/privacy for more information.

The Purple Reign Podcast
Correlation could be causation

The Purple Reign Podcast

Play Episode Listen Later Aug 12, 2024 78:12


A tough loss to the Cats puts Freo in a tough spot heading into the last two games of the season. In this episode Simon and Oz work through the GBD, Peel Talk and take on a world record number of listener questions! Get around the cathartic process of talking Freo! See omnystudio.com/listener for privacy information.

Latent Space: The AI Engineer Podcast — CodeGen, Agents, Computer Vision, Data Science, AI UX and all things Software 3.0

Thank you for 1m downloads of the podcast and 2m readers of the Substack!

united states god ceo american new york world australia english google ai apple vision voice talk americans san francisco new york times research war chinese rich australian data market european union search microsoft italian holy drop new zealand south iphone illinois selling irish code ladies chatgpt supreme court missouri memory valley os atlantic whatsapp software reddit washington post wars cloud singapore midwest philippines indonesia laugh ios scottish intelligence new yorker context mark zuckerberg scaling architecture uma oracle stopping snap bloomberg cto substack malaysia iq vc similar whispers adapt ipo southeast asia determine fireworks optimizing openai gemini residence laughing gdp gateway fusion nvidia nah acknowledge financial times hardware chess api document av wang frontier chrome blank verge 10k mojo scarlett johansson winds gorilla vertical gpt ftc nexus aws ml lama boston marathon llama small talk goldman mandarin apis bedtime ruler great lakes consensus nome amd synthetic tt frameworks band aids romain chameleons nano biases ids opus hirsch weights sam altman chai llm ops mamba skynet gpu colbert gg pdfs crowdstrike venn 5b google chrome gnome modular soit skyfall soc mozilla zuck wix cuz kv nama haiku imo rag vespa rudyard kipling gpus sonnets golden gate bridge 7b quadrants benchmarking sdks ilya perplexity ccs irobot lambda san fernando valley anthropic alessio lightspeed asics lms stack overflow crackle scarjo little italy 8b noose restful economically lex fridman cpus malay shutterstock riaa asic suno mistral inflection gcp opex tts superintelligence vertex a16z multimodal latency ozymandias larry ellison observability datadog olympiads gradient proxies asr icm baits drop zone rpc devrel mimicry netlify etched ai news cloud platforms temasek gpc sandbagging eclair jamba gbt gpd apple notes character ai augments exa neurips li bai ai engineer huggingface george hotz singlish harvard yard entropic gbd code interpreter icml ai winter phy ml ops crosstrek martin casado technium johnny ive latent space numina inprint sohu i okay
The Purple Reign Podcast
Preemptive self-defence

The Purple Reign Podcast

Play Episode Listen Later Jun 24, 2024 70:50


Call it an oxymoron or simply a proven strategy, but the Dockers have a 100% win ratio when playing someone with red hair. In this episode, we look at the tactic to ice the Suns with new fan favourite Hugh Davies in defence, we examine the GBD, including an injury to the big Moose which has huge implications on the season, we examine the stat gobblers plying their trade in the magoos, and answer some on point listener's questions. PS It's not too late to get hold of your wharfie time shirts by clicking HERESee omnystudio.com/listener for privacy information.

The Nonlinear Library
EA - Farmed animals are neglected by Vasco Grilo

The Nonlinear Library

Play Episode Listen Later Jun 24, 2024 7:41


Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Farmed animals are neglected, published by Vasco Grilo on June 24, 2024 on The Effective Altruism Forum. Summary Farmed cows and pigs account for a tiny fraction of the disability of the farmed animals I analysed. The annual disability of farmed animals is much larger than that of humans, even under the arguably very optimistic assumption of all farmed animals having neutral lives. The annual funding helping farmed animals is much smaller than that helping humans. Introduction I think one should decide on which areas and interventions to fund overwhelmingly based on (marginal) cost-effectiveness, as GiveWell does. Relatedly, I estimated corporate campaigns for chicken welfare, like the ones supported by The Humane League (THL), have a cost-effectiveness of 14.3 DALY/$, 1.44 k times that of GiveWell's top charities. However, for communication purposes, I believe it is fine to look into the benefits of fully solving a problem as well as philanthropic spending. Animal Charity Evaluators (ACE) has a great graph highlighting the neglectedness of farmed animals in the United States relative to their scale. In this post, I estimate the annual disability of and philanthropic spending on humans and farmed animals, both globally and in China[1]. The data and calculations are in this Sheet. Methods I got the annual disability of each group of farmed animals multiplying its population by its disability per living time in (human) years lived with disability (YLD) per animal-year[2], which I calculated from (1 - "welfare per time as a fraction of that of a fully healthy human as a fraction of the welfare range (normalised welfare per time)")*"welfare range". For a normalised welfare per time equal to: 0, corresponding to a neutral life, the disabilty per living time is equal to the welfare range, which makes sense. By definition, a dying human has a disability per living time of 1 YLD/year (which is equal to the welfare range of humans of 1), and a welfare per time of 0. 1, respecting a fully healthy farmed animal, the disability per living time is 0, which checks out. By definition, a fully healthy human has a disability per living time of 0, and it is natural to extend this to farmed animals. In agreement with the above, disability throughout this post refers to the potential for increasing ( affective) welfare up to the level of a fully healthy being. In contrast, the global burden of disease study ( GBD) focuses on actual disability. For simplicity, I did not consider years of life lost ( YLL). I would have to figure out the life expectancy as a function of age for farmed animals living in ideal conditions, as GBD uses a reference life expectancy for ideal human conditions. A "reference life table, or theoretical minimum risk life table (TMRLT), is used in GBD to calculate years of life lost (YLLs) due to premature mortality. It was constructed based on the lowest observed age-specific mortality rates by location and sex across all estimation years from all locations with populations over 5 million in 2016". I used Rethink Priorities' median welfare ranges. I relied on the value for pigs for cows, the mean between the values for carp and salmon for fish, and the value for black soldier flies for insects. To find the normalised welfare per time of farmed broilers, hens and decapod shrimp, I assumed: The time that farmed broilers, hens and decapod shrimp on ongrowing farms experience each of the 4 pain categories defined by the Welfare Footprint Project (WFP). I also supposed all broilers are in a conventional scenario, and that hens are in conventional cages or cage-free aviaries, using data from WFP to find the respective fractions. Excruciating pain is 1 k times as bad as disabling pain[3]. Disabling pain is 100 times as bad as hurtful pain. Hurtful pain is 10 times as bad as...

The Purple Reign Podcast
Mid season review

The Purple Reign Podcast

Play Episode Listen Later Jun 10, 2024 74:19


In this episode, the boys run through the 2024 Season through the lens of the GBD, look at the performance of Peel players knocking at the door, examine Players who have impressesd and deep dive into the Listener's Questions. Don't forget to get your hands on the limited edition Purple Reign Wharfie Time shirt by clicking here.See omnystudio.com/listener for privacy information.

Assemblage Wine Podcast
65: Wedding Recap Part I

Assemblage Wine Podcast

Play Episode Listen Later Jun 6, 2024 60:24


After nearly a month off of podcasting, the boys are back and better than ever! Adam is now a married man, and was it a cloud nine experience. Mason was of course at the wedding, but this podcast is not so much about the wedding itself. This podcast is all about their food and beverage adventures in Spain and Portugal. Hear about their favorite dining experiences and their favorite Spanish libations, and what their favorite memory was during their trip! The next podcast will be an absolute cluster f***, as our goal is to have as many people on the podcast as we possibly can to dive into Adam & Olivia's wedding day. Question of the Day: Where has been your favorite vacation spot and why? And finally, a word from our sponsor: Who's got the beef? Shoe's got the beef. Shoe's pizzeria keeps it close to home by highlighting the Chicago Beef. They soak perfectly cooked thin sliced Italian beef in hot au jus, before placing it in a freshly baked roll. They top it off with mozzarella before baking it to perfection. And you know when that is? When the mozzarella starts to create a GBD (golden brown delicious) crust on top. They then serve it with peperoncini peppers and more au jus. Adam's personal favorite way to eat it is by adding some hot giardinara and a side of their crinkle cut fries. Go check out Shoe's, and see if you can take down their 6” or 12” beef sandwich. Tell Chris that Mason + Adam told you about it and he will give you a free beer to wash that beef down (must be 21 years or older to get this offer). 3300 N Calumet Ave, Valparaiso IN. --- Support this podcast: https://podcasters.spotify.com/pod/show/assemblagebeveragepodcast/support

The Purple Reign Podcast
Living the dream in Alice!

The Purple Reign Podcast

Play Episode Listen Later Jun 3, 2024 57:05


Freo put the D's to the sword in the most comprehensive performance of the season. With a four quarter stunner vs a hapless outfit, Freo showed 92 reasons why they can be left standing when all is said and done. Freo supporters are up and about with a range of questions, with the GBD and Macho Man of the Week bound to stir the emotions. Don't forget you can get your Wharfie Time shirts by clicking HERESee omnystudio.com/listener for privacy information.

The Purple Reign Podcast
He's been doing it all day umpire!

The Purple Reign Podcast

Play Episode Listen Later May 27, 2024 52:03


In a closely fought contest the mighty Freo Dockers drew on the Wharfie Time inspiration to come back Lazarus style to conjure a draw from the jaws of defeat. In this episode we deep dive the GBD, pay homage to the Macho Man of the Week, and hit up some great listener's questions. We are hoping to get 30,000 fans in Wharfie Time T's to set up an intimidating atmosphere! Get your piece of Wharfie Time via the following link Wharfie Time T-shirt See omnystudio.com/listener for privacy information.

L'Histoire nous le dira
Folles théories historiques sur le diabète | L'Histoire nous le dira # 249 avec @Charlesco

L'Histoire nous le dira

Play Episode Listen Later May 15, 2024 42:05


Le nombre de diabétiques a quadruplé depuis les 30 derrières années... mais ça vient d'où le diabète ? Adhérez à cette chaîne pour obtenir des avantages : https://www.youtube.com/channel/UCN4TCCaX-gqBNkrUqXdgGRA/join Video tournée avec le Dr Gilbert Bou Jaoudé, médecin sexologue et andrologue. Consultez son site sur Youtube: https://www.youtube.com/@Charlesco Script: Françoise Dulong et équipe Charles.co Montage: Charles.co Pour soutenir la chaîne, au choix: 1. Cliquez sur le bouton « Adhérer » sous la vidéo. 2. Patreon: https://www.patreon.com/hndl Musique issue du site : epidemicsound.com Images provenant de https://www.storyblocks.com Abonnez-vous à la chaine: https://www.youtube.com/c/LHistoirenousledira Les vidéos sont utilisées à des fins éducatives selon l'article 107 du Copyright Act de 1976 sur le Fair-Use. Sources et pour aller plus loin: Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021” GBD 2021 Diabetes Collaborators, June 22, 2023 Dictionnaire Larousse https://www.larousse.fr/dictionnaires/francais/diabète/25108 Le texte médical du Papyrus Ebers Transcription hiéroglyphique, translittération, traduction, glossaire et index, Bernard Lalanne et Gérard Métra. 2017 Coll. Langues et cultures anciennes. Celse, traité de la médecine en 8 livres, (traduction par Charles des Etangs) Paris, Dubocher, Le Chevalier et cie., 1846. Livre IV, Ch XX, par 2, p118 RENAUD M.L. Traité des signes, des causes et de la cure des maladies aigües et chroniques; ouvrage d'Aréthée (traduit du grec) 1 volume in-80,XVIII-422IV pages. Paris, Lagny, 1834 DAREMBERG Ch. Œuvres anatomiques, physiologiques et médicales de Galien (traduction française) 2 volumes in-80, XVI-706 et 784 pages, Paris, Baillière, 1856 Histoire illustrée du diabète, de l'Antiquité à nos jours, J-J. Peumery, Les éditions Roger Dacosta, Paris, déc 1987 A Bouchardat , Diabète sucré, son traitement hygiénique , Paris, 1883 J.A. Leouffre, De la glycosurie ou diabète sucré, Paris, 1854, no 259, 55 pages Regimen sanitaris, Arnaldus de Villanova, Lyon, 1504 https://collections.nlm.nih.gov/catalog/nlm:nlmuid-2211085R-bk Dictionnaire de l'encyclopediae universalis, 2023 https://www.universalis.fr/atlas/ Histoire du diabète, Ph. Vague et B. Vialettes Hôpital du Petit-Arbois. Centre hospitalo-universitaire de Marseille. 13290 Les Milles. Nicolas, Pierre-François et Gueudeville Victor, Recherches et expériences médicales sur le diabète sucré et la phthisurie sucrée, 1 volume in-80, 99 pages, Paris, Méquignon, 1803 Le diabète dans le monde : classement par pays, 26 Oct 2022 https://www.dbl-diabete.fr/tout-sur-le-diabete/societe/classement-diabete-pays-monde Qu'est-ce que le diabète, Nov 2021 https://www.diabete.qc.ca/le-diabete/informations-sur-le-diabete/quest-ce-que-le-diabete/ Vins de Bourgogne, lexique https://www.vins-bourgogne.fr/glossaire/austere,2530,9410.html?&args=Y29tcF9pZD0xNTU5JmFjdGlvbj12aWV3R2xvc3NhaXJlJmlkPSZtb3Q9NzB8#_ La langue française, dictionnaire https://www.lalanguefrancaise.com/dictionnaire/definition/leucophlegmatie The Starvation Treatment of Diabetes par Lewis Webb Bill, M.D. et Rena S. Eckman, diététicienne. 1915. Le diabète sucré https://fr.wikipedia.org/wiki/Diabète_sucré Traité du diabète sucré, des affections gastriques et des maladies qui en dépendant, par John Rollo, traduit de l'anglais par Alyon, 1 volume in-80. Paris, Montardier-Cérioux, An VI (1797) Fédération française des diabétiques https://www.federationdesdiabetiques.org/information/recherche-innovations-diabete/decouverte-insuline#:~:text=Sur%20la%20piste%20de%20l%27insuline&text=L%27étudiant%20en%20médecine%20allemand,nom%20%3A%20les%20îlots%20de%20Langerhans Diabète Québec https://www.diabete.qc.ca/le-diabete/informations-sur-le-diabete/quest-ce-que-le-diabete/ HISTOIRE DU DIABÈTE AUX TEMPS ANCIENS: Diabète dans tous ses états, le 22/08/2022, Marc Gozlan https://www.le-diabete-dans-tous-ses-etats.precidiab.org/histoire-du-diabete/histoire-du-diabete-aux-temps-anciens/ Le taux mondial du diabète augmenteront de 529 millions cas à 1,3 milliard cas par 2050 On s'attend que chaque pays du monde verra une augmentation des taux. SEATTLE, Wash. 22 juin 2023 https://www.healthdata.org/sites/default/files/files/images/news_release/2023/French_GBD%202021%20Diabetes%20News%20Release.pdf Événement historique national de la découverte de l'insuline, 2022-12-01 https://parcs.canada.ca/culture/designation/evenement-event/decouverte-insuline-insulin-discovery# Diabète https://www.paho.org/fr/sujets/diabete#:~:text=Le%20nombre%20des%20personnes%20atteintes,%25%20en%202014%20(1) Un portrait complet du diabète de type 1 dans le monde, 2022 https://ici.radio-canada.ca/nouvelle/1923169/diabete-de-type-1-portrait-complet-planete Autres références disponibles sur demande.

The Purple Reign Podcast
Vale Cam McCarthy

The Purple Reign Podcast

Play Episode Listen Later May 13, 2024 61:48


Following Cam McCarthy's tragic passing, 24 hours later the scheduled Friday night Freo vs. Swans clash went ahead, with the end result and images of emotional players suggesting this fixture should not have gone ahead. In this episode, the boys keep it real and discuss the fixture, whether the game should have gone ahead, and how something positive can be worked between GWS and Freo in memory of Dardy, along with a different take on the GBD and the Macho Man of the week.See omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Nothing to see here!

The Purple Reign Podcast

Play Episode Listen Later Mar 4, 2024 54:32


In the final pre-season hit out the mighty Freo Dockers went down to a strong Port outfit. In this episode, we run through the GBD, with an eye on the starting 22 for round 1. A good healthy debate on the forward structure and also how the back line may look come first round v Lions. Listener's questions probe the inevitable starting 22 vibe and some great future related questions on Freo.See omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Bring back the Scratch Match name!

The Purple Reign Podcast

Play Episode Listen Later Feb 25, 2024 69:04


In the first match-sim podcast for 2024, the boys are back to discuss the Freo v WC match sim held at the mighty Lathlain Oval. The boys deep dive into the GBD, and discuss potential movers and shakers for the 2024 season. The listener questions are on point and provide some much needed pod practice. Thankfully there were no pre-season injuries heading into the season proper.See omnystudio.com/listener for privacy information.

Bret Weinstein | DarkHorse Podcast
The Science of Conspiracy: The 211th Evolutionary Lens with Bret Weinstein and Heather Heying

Bret Weinstein | DarkHorse Podcast

Play Episode Listen Later Feb 7, 2024 137:11


In this 211th in a series of live discussions with Bret Weinstein and Heather Heying (both PhDs in Biology), we talk about the state of the world through an evolutionary lens.In this episode, we discuss Winter and seasonality, before a longer discussion of overfitting, shoe-horning, and straight-jacketing. How do models, collusion, and Occam's Razor contribute to how we understand the world? Why are generalists better situated to interpret complexity than are specialists? Then: how good is the science behind the major paper out of The Lancet that assures us that we should not be eating red meat? Answer: not very. Finally, we discuss the orcas who were trapped in sea ice off of Japan, and what it means to be an orca (including mention of the grandmother hypothesis).*****Our sponsors:MDHearing: To get our $397 when you buy a PAIR offer, head to Shopmdhearing.com and use code DARKHORSE.  Helix: Excellent, sleep-enhancing, American-made mattresses. Go to www.HelixSleep.com/DarkHorse and use code HELIXPARTNER20 to get up to 20% of all mattress orders AND 2 free pillows.ARMRA: Colostrum is our first food, and can help restore your health and resilience as an adult. Go to www.tryarmra.com/DARKHORSE to get 15% off your first order.*****Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/Heather's newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.comOur book, A Hunter-Gatherer's Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://a.co/d/dunx3atCheck out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org*****Mentioned in this episode:The Emperor of Scent by Chandler Burr (about Luca Turin): https://www.amazon.com/Emperor-Scent-Story-Perfume-Obsession/dp/0375759816 Willett et al 2019. Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems. Lancet 393, 447–492: https://www.thelancet.com/action/showPdf?pii=S0140-6736%2818%2931788-4Stanton 2024. Unacceptable use of substandard metrics in policy decisions which mandate large reductions in animal-source foods. Npj Science of Food 8(10): https://www.nature.com/articles/s41538-024-00249-yStanton et al 2022. 36-fold higher estimate of deaths attributable to red meat intake in GBD 2019: is this reliable?. The Lancet, 399(10332), pp.e23-e26.: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00311-7/fulltextSupport the show

We Want Them Infected Podcast
PT2: Debating the Merits of the Great Barrington Declaration

We Want Them Infected Podcast

Play Episode Listen Later Jan 21, 2024 35:53


The GBD, penned in October 2020, proposed an alternative strategy to the prevailing COVID-19 restrictions. It suggested that low-risk populations should be allowed to acquire natural immunity through infection, while high-risk groups, particularly the elderly and those with pre-existing conditions, receive focused protection. This approach, the authors argued, would lead to herd immunity, reducing overall societal and economic disruptions. Questionable Origins and Ideological Underpinnings The hosts addressed the origins of the GBD, noting its association with the American Institute for Economic Research, a libertarian think tank. This connection raised questions about the ideological motives behind the declaration, potentially conflating public health policy with economic and political agendas. Jeffrey Tucker: A Controversial Figure Central to the episode's critique was the examination of Jeffrey Tucker, a significant proponent of the GBD. Tucker's controversial views on child labor and pro-tobacco stances, as highlighted in the podcast, painted a picture of an individual whose ideologies might conflict with mainstream public health principles. The Impact on Public Health Policy The GBD's influence on public health policy has been substantial, igniting debates on pandemic management strategies. Its advocacy for herd immunity through natural infection contrasted sharply with the broader public health consensus advocating for vaccination and preventive measures. Closing: Learning from the Pandemic The analysis presented here underscores the complexities of pandemic management and the importance of scrutinizing the origins, motivations, and implications of public health policies. The Great Barrington Declaration, with its controversial stance and ideological underpinnings, serves as a case study in the critical evaluation of health policy during unprecedented times.   Resources mentioned: Great Barrington Declaration. Interviews and quotes from Dr. Scott Atlas and Dr. Jerome Adams. Statements from Dr. Vinay Prasad and Dr. Jay Bhattacharya. Information about the American Institute for Economic Research. Articles and viewpoints of Jeffrey Tucker. COVID-19 pandemic response policies and their impacts. Various epidemiological studies and data cited in the podcast. Historical context of public health measures during the pandemic. Connect with us further on jonathanhowardmd.com  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

Cytokine Signalling Forum
Discussing Rheumatology: November 2023

Cytokine Signalling Forum

Play Episode Listen Later Nov 23, 2023 10:11


Join Professor Iain McInnes in this month's CSF Podcast, where he discusses the latest information and data in rheumatology. In this episode, he discusses two papers that look at the incidence of disease. The first paper, the GBD 2021 Other Musculoskeletal Disorders Collaborators systematically analysed the global burden of musculoskeletal disorders, and used these data to predict prevalence up to 2050 and the second paper, Yvette Meissner and her colleagues used the German RABBIT registry to investigate the relationship between MACE risk and JAK inhibitors, TNF inhibitors, and DMARDs. To access detailed summary slides for the papers discussed today, visit cytokinesignalling.com.

Cytokine Signalling Forum
Discussing Rheumatology: October 2023

Cytokine Signalling Forum

Play Episode Listen Later Oct 20, 2023 11:17


Join Professor Iain McInnes in this month's CSF Podcast, where he discusses the latest information and data in rheumatology. In this episode, he discusses two papers that look at the epidemiology of autoimmune diseases. The first paper, the GBD 2021 Rheumatoid Arthritis Collaborators systematically reviewed the global RA burden, and used these data to predict prevalence up to 2050 and the second paper, Nathalie Conrad and her colleagues reported the incidence and prevalence of 19 different autoimmune disorders in the United Kingdom, while also stratifying by age, sex, and socioeconomic status. To access detailed summary slides for the papers discussed today, visit cytokinesignalling.com.

The Purple Reign Podcast
Season 8 Episode 28 - Season Review

The Purple Reign Podcast

Play Episode Listen Later Sep 14, 2023 70:38


With 2023 in the books, the boys look back to the season as it was. We run through the GBD and Macho Man of the Year, Peel Finals Talk, and answer great listener questions. See omnystudio.com/listener for privacy information.

Business Matters
Japan's GDP grows more than expected

Business Matters

Play Episode Listen Later Aug 15, 2023 50:16


The gross domestic product (GDP) figure translated to a quarterly increase of 1.5%. It's the third straight quarter of expansion led by external demand and expanded exports by 3.2% respectively. The positive GBD data was driven by exports of goods such as automobiles as supply chain constraints, including shortage of semiconductors, eased. Recovering inbound tourism after the COVID-19 pandemic also contributed to the services exports. (Picture: Japan flag and Japanese Yen cash bills. Picture credit: Getty Images)

The Purple Reign Podcast
Season 8 Episode 23 - GMHBA a home away from home!

The Purple Reign Podcast

Play Episode Listen Later Jul 31, 2023 60:27


The boys put on a show for the ages with a gritty and lively performance vs a full-strength Geelong at GMHBA Stadium. The team played the sort of game that justified pre-season expectations for the top 8. In this episode we look at the difference between our best and being slightly off, with an extended GBD and Macho Man of the week. The result has listeners up and about with great questions, and the referee has not slapped the full three count on the season just yet...See omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Season 8 Episode 22 - The blueprint?

The Purple Reign Podcast

Play Episode Listen Later Jul 24, 2023 71:05


In 12 minutes of football, the Swans kicked away to an unassailable lead in the first quarter. Outside the 12 mins, Freo showed dare, dash and flair, which may be the blueprint for success moving forward. In this episode, we deep dive into the GBD, look at some of the remaining Docker-listed players at Peel who have yet to debut, debate the current make-up of the team, and answer some quality Listener's Questions.See omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Season 8 Episode 21 - Too Fast, Too Furious

The Purple Reign Podcast

Play Episode Listen Later Jul 16, 2023 71:10


The boys in purple could not withstand a 2nd quarter onslaught from the Pies, conceding ten goals and ultimately the match in an otherwise strong performance. In this episode, the GBD investigates the good, what went wrong, the Macho Man of the Week and the Dockery moments from the game. With finals now out of the picture, Peel Talk covers the potential ins for injured duo Walker and Darcy and discusses how close young guns such as Sebit Kuek and Josh Draper are from their debut. As usual, there is a tonne of epic Listener's Questions and, of course, a deep dive into the future of the list.See omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Season 8 Episode 20 - Finding the positives

The Purple Reign Podcast

Play Episode Listen Later Jul 10, 2023 70:06


In a disappointing performance, the mighty Freo Dockers were outplayed and outworked by Carlton. Looking at the game through rose-coloured glasses, the youth have another game to reflect and grow from, with a perfect opportunity to review and set the standards for success in future years. The GBD deep dives into the unknown, and with some players knocking down the door at Peel, there are opportunities for those in the wings in the remaining games of season 2023.See omnystudio.com/listener for privacy information.

Pete McMurray Show
Is micro-cheating cheating? What is cheating? Let's go through the list #MicroCheating

Pete McMurray Show

Play Episode Listen Later Jul 4, 2023 7:01


Is micro-cheating cheating?  #MicroCheating -Is it-It's not physically touching-Flirting on text-GBD-and many more examples Photo Courtesy: Ryan Answers

The Purple Reign Podcast
Season 8 Episode 19 - The Business Cycle personified

The Purple Reign Podcast

Play Episode Listen Later Jul 3, 2023 77:46


Freo's roller-coaster season continued with a tough loss against the Bulldogs. In this episode, Duck and Oz deep dive into the GBD and attempt to answer some tough questions on the current list moving forward. As always, the boys examine the Freo-listed Peel players knocking at the door and answer some potentially award-winning Listener's questions.See omnystudio.com/listener for privacy information.

The Illusion of Consensus
Episode 5: Unraveling The Destructive Censorship Industrial Complex

The Illusion of Consensus

Play Episode Listen Later Jun 15, 2023 100:39


Censorship Podcast AgendaOverview: Throughout the pandemic, opponents of lockdowns, school closures, mask mandates, vaccine mandates, and other pandemic restrictions have felt the decks have been stacked against them in sharing their message on social media, especially Facebook, Twitter, Reddit, and YouTube.Detailed show notes of podcast:Early pandemic censorship* Zuckerburg email to Fauci offering to help* Aaron Ginn and AJ Kay censorship in March / April 2020. They both argued a hypothesis that covid had spread more widely than public health realized then, and that the infection fatality rate was likely lower than the case fatality rate. Medium censored their essays for being dangerous for public health.* In April 2020, Santa Clara study I went on NPR to explain the results. The reporter asked me if I was worried that people would intentionally seek out getting covid (e.g. covid parties).* In late April/May 2020, I gave an interview where I mentioned that contact tracing was largely useless given the mode and ease of spread of covid. The Stanford human subjects review board – for a study that had nothing to do with contact tracing – mentioned this interview as a potential human subjects violation in a bid to silence me.* In 2020 Ontario Canada, doctors who wrote about natural immunity on twitter (e.g. Dr. Kulvinder Gill) faced censure from medical boards with risk of losing license.* Heavy censorship of early treatment options in online settings. Discussion about whether this was appropriate. Some of the early results for cheap, safe drugs were promising. Why not let people try them for a disease that was deadly in older people?* The clear purpose of these censorship efforts was to create fear in the population and gain compliance regarding lockdown orders.Censorship of the GBD* GBD signed on October 2020* Collins email to Fauci / fringe epidemiology / devastating takedown* WHO says no such thing as herd immunity* Google deboosted search results / hit pieces came first* Facebook took down the GBD page for a week without explanation* Reddit slapped down accounts mentioning the GBD and limited discussion of it.Censorship and Propaganda in 2021* With the advent of the vaccine, propaganda and censorship efforts by governments intensified.* Government officials vastly overstated the results of the clinical trials re: infection blocking. This included Fauci, Walensky, etc.* Governments engaged celebrities. FB highilghted posts of young attractive people bragging about getting vaccinated early, even while millions of older people who would have benefited more did not get a vaccine until late.* DeSantis Roundtable March 2021. Masking children Youtube pulls the video* Severe censorship of vaccine discussion online (e.g. Alex Berenson on effectiveness of the vaccine vs. disease spread; Naomi Wolf on menstrual problems caused by the vax)* Twitter files blacklistGovernment Role in Censorship* As 2021 rolled on, the vaccine campaign fizzled out. The government turned to censorship and mandates to fix the problem.* In Berenson case government officials like Andy Slavitt directly wrote to Twitter to ban Alex.* Missouri vs. Biden.  Dozen federal agencies involved in the censorship effort, including the White House, CDC, Office of the Surgeon General. The government threatened section 230 status. Direct line of communication from white house to twitter, FB regarding censsorship. Topics inlcuded true facts (e.g. ineffectiveness of vaccine at blocking infection).* Even the White House itself caught up in censorship J&J pause* Censorship efforts often informed by Stanford virality project & a “disinformation” team at the University of Washington* Use of AI algorithms, with word lists sent by the government, for widescale censorship* Roots of censorship apparatus linked to national security concerns. Obama signed “On Dec. 23, 2016, he signed into law the Countering Foreign Propaganda and Disinformation Act, which used the language of defending the homeland to launch an open-ended, offensive information war.”Government as #1 source of misinformation* Indiana AG letter* Overcounting covid cases* Questioning natural immunity* Covid vax prevents transmission* School closures effective and costless* Everone equally at risk of dying from covid infection* No policy alternative available to lockdown* Mask mandates effective in reducing covid spread* Mass asymptomatic testing and contact tracing effective in reducing covid spread* Eradication of covid is a feasible goal. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.illusionconsensus.com/subscribe

The Purple Reign Podcast
Season 8 Episode 16 - Tough Loss to Tigers

The Purple Reign Podcast

Play Episode Listen Later Jun 12, 2023 66:46


On a dark and rainy evening, the Dockers started brightly, only to fall behind to an accurate Tigers outfit who were clinical in the clinches. Making finals is now an uphill battle, but in this episode, we discuss why this is still a red-hot possibility. We run through the GBD, who's knocking the door down at Peel, and as always, answer as many Listener's questions as possible.See omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Season 8 Episode 14 - Walyalup undefeated!

The Purple Reign Podcast

Play Episode Listen Later May 29, 2023 68:30


The boys are up and about following a stirring win at the 'G' v Narm. Heading into the bye with all the momentum, the boys hit the ground running with a super positive GBD, Peel Talk and some of the best Listener's Questions in the history of the pod! Keep the great questions rolling in, and don't forget to share with a fellow Freo tragic and spread the word.See omnystudio.com/listener for privacy information.

Mind the Shift
106. The Censorship Industrial Complex – Jay Bhattacharya

Mind the Shift

Play Episode Listen Later May 24, 2023 72:19


Everybody wants to forget about the pandemic, this bizarre period of aberrations. But the assessment of what played out and whether the many harsh policy decisions were called for has only begun. One of the saddest aberrations was infringements on freedom of speech. Few have experienced that more than Jay Bhattacharya, professor of health policy at Stanford. As one of the initiators of the Great Barrington Declaration (GBD), he was actively silenced by the government, which, it turns out, orchestrated a censorship campaign by way of the social media companies. The GBD promoted focused protection instead of sweeping lockdowns: Shield the elderly and let the young go to school. The signatories opined, on evidential grounds, that lockdowns were more harmful than the disease. They based their proposition on the fact that there is an extremely steep age gradient in the risk of dying from covid. There were early signs that this view was held by thousands of doctors. But the ruling class was not amused. People like Francis Collins, head of the NIH, wanted to take down the declaration, and its initiators were ostracized and censored. ”My life is fundamentally transformed”, says Jay Bhattacharya. ”I used to be a quiet scientist, but during the pandemic, I have had to take a very public role. That has been in some ways gratifying, but at the same time it has been traumatic. Many friendships have been broken.” At one point, he says, one hundred of his colleagues circulated a silent petition to try to get the president of Stanford university to silence him. ”I have had lots of practice in how to forgive other people.” Since the summer of 2022, a lawsuit has been underway in which the Biden administration is accused of breaching the First Amendment, which protects freedom of speech. Jay Bhattacharya is one of the plaintiffs. ”The evidence of this is remarkable. Government officials have coerced social media companies to censor ideas and certain people”, Jay says. ”There is a censorship network in the government and a dozen agencies. You could call it a ministry of truth”, Jay says, referring to a term in George Orwell's dystopian novel Nineteen Eighty-Four. ”This is the most important First Amendment case since at least the Pentagon papers (NYT v. USA; 1971). It's been shocking to see the American government behave in this way.” According to Jay, the censorship may actually have led to more deaths than almost any other single policy, because harmful errors were not corrected in time. Jay thinks the lawsuit will go all the way up to the Supreme Court. – I don't see how the government can win this. In this episode we also talk about • What the GBD did and did not propose. • How the declaration has been vindicated. • The Swedish pandemic model (”the best in the world”). • How leaders in almost the whole world were hypnotized by the draconian Chinese measures. • The continuous excess deaths (primarily caused by extended lockdown harm, according to Jay). • That more power to WHO is a ”terrible idea”. The Great Barrington Declaration: https://gbdeclaration.org/ The lawsuit: https://nclalegal.org/state-of-missouri-et-al-v-joseph-r-biden-jr-et-al/ Jay at Stanford: https://profiles.stanford.edu/jay-bhattacharya

The Purple Reign Podcast
Season 8 Episode 13 - Vroom vroom

The Purple Reign Podcast

Play Episode Listen Later May 22, 2023 55:13


After a stirring performance by the Walyalup boys, we are now sniffing around the 8 and looking to slipstream into finals contention. In this episode, the Reign deep dives into the transformation over the last three weeks and, as usual, run through the GBD, Macho Man of the Week, Peel Talk and Listener's questions. See omnystudio.com/listener for privacy information.

The EMJ Podcast: Insights For Healthcare Professionals
Bonus Episode: Discussing Disease Burden and Importance of Routine Vaccination Against Rotavirus Gastroenteritis

The EMJ Podcast: Insights For Healthcare Professionals

Play Episode Listen Later Apr 24, 2023 19:15


In this podcast, an experienced conference and webinar moderator is joined by two doctors in the field of paediatric infectious diseases: David Greenberg and Maria Hemming-Harlo. In this podcast, our guest experts provide information and their perspectives on the following topics: The disease burden of rotavirus The related morbidity and mortality of rotavirus How rotavirus is transmitted The clinical picture of rotavirus infection The evidence supporting routine vaccination with RotaTeq (Rotavirus Vaccine, Live, Oral, Pentavalent) This podcast was funded by Merck Sharp & Dohme LLC. Below please find the reference list for Vax Voices, Podcast 1: The Global Burden of Rotavirus Disease and Evidence Supporting Routine Vaccination With RotaTeq to ensure listeners can further explore the content discussed. View the product information and indication for RotaTeq here. View the Select Safety Information from MSD below. Select Safety Information RotaTeq should not be administered to infants with a demonstrated history of hypersensitivity to the vaccine or any component of the vaccine. Infants with a history of intussusception or who have congenital malformation of the gastrointestinal tract that could predispose infants to intussusception should not receive RotaTeq. Infants with Severe Combined Immunodeficiency Disease or SCID should not receive RotaTeq. Administration of RotaTeq should be postponed in infants suffering from acute severe febrile illness. The presence of a minor infection is not a contraindication for immunisation. The administration of RotaTeq should be postponed in subjects suffering from acute diarrhoea or vomiting. No safety or efficacy data are available from clinical trials regarding the administration of RotaTeq to infants who are potentially immunocompromised. Cases of gastroenteritis associated with vaccine virus have been reported post marketing in infants with severe combined immunodeficiency. Vaccine virus transmission from vaccine recipient to nonvaccinated contacts has been reported. Caution is advised when considering whether to administer RotaTeq to individuals with immunodeficient contacts. In post-marketing experience, intussusception (including death) and Kawasaki disease have been reported in infants who have received RotaTeq. As a precaution, healthcare professionals should follow-up on any symptoms indicative of intussusception (severe abdominal pain, persistent vomiting, bloody stools, abdominal bloating and/or high fever) since data from observational studies indicate an increased risk of intussusception, mostly within 7 days after rotavirus vaccination. Parents/guardians should be advised to promptly report such symptoms to their healthcare provider. The level of protection provided by RotaTeq is based on the completion of all 3 doses. As with any vaccine, vaccination with RotaTeq may not result in complete protection in all recipients. HQ-ROT-00133 | 02/23   Podcast References: 1.Nelson R. COVID-19 disrupts vaccine delivery. Lancet Infect Dis. 2020;20(5):546. 2.Centers for Disease Control and Prevention (CDC). Epidemiology and Prevention of Vaccine-Preventable Diseases. 14th ed. Chapter 19: Rotavirus. Available at: https://www.cdc.gov/vaccines/pubs/pinkbook/rota.html. Last accessed: 6 March 2023. 3.Dormitzer PR. "Rotaviruses," Mandell GL, et al, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier Saunders; 2019:1983-96. 4.Centers for Disease Control and Prevention (CDC). Rotavirus. Clinical information. 2021. Available at: https://www.cdc.gov/rotavirus/clinical.html. Last accessed: 13 October 2022. 5.Troeger C et al. Rotavirus vaccination and the global burden of rotavirus diarrhea among children younger than 5 years. JAMA Pediatr. 2018;172(10):958-965. Erratum in: JAMA Pediatr. 2022;176(2):208. 6.GBD Diarrhoeal Diseases Collaborators. Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Infect Dis. 2017;17(9):909-948. Erratum in: Lancet Infect Dis. 2017 Sep;17(9):897. 7.Van Damme P et al. Rotavirus vaccines: considerations for successful implementation in Europe. Lancet Infect Dis. 2006;6(12):805-12. 8.Paul MO, Erinle EA. Influence of humidity on rotavirus prevalence among Nigerian infants and young children with gastroenteritis. J Clin Microbiol. 1982;15(2):212-5. 9.Finnish Institute for Health and Welfare. Infectious diseases and vaccines: rotavirus vaccine. 2020. Available at: https://thl.fi/en/web/infectious-diseases-and-vaccinations/vaccines-a-to-z/rotavirus-vaccine. Last accessed: 16 September 2022. 10.GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117-71. 11.Franco MA et al. Immunity and correlates of protection for rotavirus vaccines. Vaccine. 2006;24(15):2718-31. 12.Gentsch JR et al. Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs. J Infect Dis. 2005;192(Suppl 1):S146-59. 13.Merck & Co. RotaTeq®. Prescribing information. 2022. Available at: https://www.merck.com/product/usa/pi_circulars/r/rotateq/rotateq_pi.pdf. Last accessed: 4 January 2023. 14.European Medicine Agency (EMA). RotaTeq. Summary of product characteristics. 2022. Available at: https://www.ema.europa.eu/en/documents/product-information/rotateq-epar-product-information_en.pdf. Last accessed: 4 January 2023. 15.Velasquez-Portocarrero DE et al. Head-to-head comparison of the immunogenicity of RotaTeq and Rotarix rotavirus vaccines and factors associated with seroresponse in infants in Bangladesh: a randomised, controlled, open-label, parallel, phase 4 trial. Lancet Infect Dis. 2022;22(11):1606-16. 16.Cortese MM, Parashar UD; Centers for Disease Control and Prevention (CDC). Prevention of rotavirus gastroenteritis among infants and children: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2009;58(RR-2):1-25. 17.Vesikari T et al.; Rotavirus Efficacy and Safety Trial (REST) Study Team. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med. 2006;354(1):23-33. 18.Vesikari T et al. Efficacy of a pentavalent rotavirus vaccine in reducing rotavirus-associated health care utilization across three regions (11 countries). Int J Infect Dis. 2007;11(Suppl 2):S29-35. 19.Heyse JF; REST Study Team. Evaluating the safety of a rotavirus vaccine: the REST of the story. Clin Trials. 2008;5(2):131-9. 20.World Health Organization (WHO). Rotavirus vaccines: WHO position paper. Wkly Epidemiol Rec. 2021;96(28):301-20.  

The Purple Reign Podcast
Season 8 Episode 8 - Gather this baby!

The Purple Reign Podcast

Play Episode Listen Later Apr 17, 2023 62:44


At a Dockery time and in a Dockery footy dimension, the boys dressed in the Stealth kit broke the hearts of Suns supporters and many media pundits. A wise man once said, "We will no go quietly into the night!" The boys put on a second-half performance that could be the catalyst for booking the bus in the coming weeks. In this episode, we cover the GBD, Macho Man of the Week, BDE, Peel Talk, Listener's Questions, and of course, we dream big for our Friday night clash with the Dogs.See omnystudio.com/listener for privacy information.

Create Your Own Destiny Podcast
The New Girlboss Designer is Here

Create Your Own Destiny Podcast

Play Episode Listen Later Apr 5, 2023 30:27


Drum roll please … we've been working behind the scenes for months on something special—and now the big reveal is ready for you!  We're known for creating beautiful brands for our clients, but this time, we've given GBD a facelift. Introducing the new, elevated version of Girlboss Designer—complete with a brand-new website experience. In the episode, I walk you through what's different about our new website setup that I've never seen done before, plus the new design templates and courses we've added. We hope you love the new tailored experience as much as we do!

Latent Space: The AI Engineer Podcast — CodeGen, Agents, Computer Vision, Data Science, AI UX and all things Software 3.0
Emergency Pod: ChatGPT's App Store Moment (w/ OpenAI's Logan Kilpatrick, LindyAI's Florent Crivello and Nader Dabit)

Latent Space: The AI Engineer Podcast — CodeGen, Agents, Computer Vision, Data Science, AI UX and all things Software 3.0

Play Episode Listen Later Mar 24, 2023 96:16


This blogpost has been updated since original release to add more links and references.The ChatGPT Plugins announcement today could be viewed as the launch of ChatGPT's “App Store”, a moment as significant as when Apple opened its App Store for the iPhone in 2008 or when Facebook let developers loose on its Open Graph in 2010. With a dozen lines of simple JSON and a mostly-english prompt to help ChatGPT understand what the plugin does, developers will be able to add extensions to ChatGPT to get information and trigger actions in the real world. OpenAI itself launched with some killer first party plugins for: * Browsing the web, * writing AND executing Python code (in an effortlessly multimodal way), * retrieving embedded documents from external datastores,* as well as 11 launch partner plugins from Expedia to Milo to Zapier.My recap thread was well received:But the thing that broke my brain was that ChatGPT's Python Interpreter plugin can run nontrivial code - users can upload video files and ask ChatGPT to edit it, meaning it now has gone beyond mere chat to offer a substantial compute platform with storage, memory and file upload/download. I immediately started my first AI Twitter Space to process this historical moment with Alessio and friends of the pod live. OpenAI's Logan (see Episode 1 from *last month*…) suggested that you might be able to link ChatGPT up with Zapier triggers to do arbitrary tasks! and then Flo Crivello, who just launched his AI Assistant startup Lindy, joined us to discuss the builder perspective.Tune in on this EMERGENCY EPISODE of Latent Space to hear developers ask and debate all the issues spilling out from the ChatGPT Plugins launch - and let us know in the comments if you want more/have further questions!SPECIAL NOTE: I was caught up in the hype and was far more negative on Replit than I initially intended as I tried to figure out this new ChatGPT programming paradigm. I regret this. Replit is extremely innovative and well positioned to help you develop and host ChatGPT plugins, and of course Amjad is already on top of it:Mea culpa.Timestamps* [00:00:38] First Reactions to ChatGPT Plugins* [00:07:53] Q&A: Keeping up with AI* [00:10:39] Q&A: ChatGPT Intepreter changes Programming* [00:12:27] Q&A: ChatGPT for Education* [00:15:21] Q&A: GPT4 Sketch to Website Demo* [00:16:32] Q&A: AI Competition and Human Jobs* [00:18:44] ChatGPT Plugins as App Store* [00:34:40] Google vs ChatGPT* [00:36:04] Nader Dabit on Selling His GPT App* [00:43:16] Q&A: ChatGPT Waitlist and Voice* [00:45:26] LangChain with Human in the Loop* [00:46:58] Google vs Microsoft vs Apple* [00:51:43] ChatGPT Plugin Ideas* [00:53:49] Not an app store?* [00:55:24] LangChain and the Future of AI* [01:00:48] Q&A: ChatGPT Bots and Cronjobs* [01:04:43] Logan Joins Us!* [01:07:14] Q&A: Plugins Rollout* [01:08:26] Q&A: Plugins Discovery* [01:10:00] Q&A: OpenAI vs BingChat* [01:11:03] Q&A: App Store Monetization* [01:14:45] Q&A: ChatGPT Plugins API* [01:17:17] Q&A: Python Interpreter* [01:19:58] The History of App Stores and Marketplaces* [01:22:40] LindyAI's Flo Crivello Joins Us* [01:29:42] AI Safety* [01:31:07] Multimodal GPT4* [01:32:10] Designing AI-safe APIs* [01:34:39] Flo's Closing CommentsTranscript[00:00:00] Hello and welcome to the Latent Space Emergency episode. This is our first ever where chatty PT just dropped a plugin ecosystem today, or at least they demoed their plugins. It's still on the wait list, but it is the app store moment for ai. And we did an emergency two hour space with Logan from OpenAI and Flo Coveo from Lin AI and a bunch of our friends.[00:00:28] And if you ever wanted to listen to what it's like to hear developers process in real time when a new launch happens, this is it. Enjoy,[00:00:38] First Reactions to ChatGPT Plugins[00:00:38] I assume everyone has read the blog post. For me the, the big s**t was do you see Greg Brockman's tweet about FFMPEG? I did not. I should check it out. It is amazing. Okay, so. So ChatGPT can generate Python code. We knew this, this is not new, and they can now run the code that it generates.[00:00:58] This is not new. I mean this is like, this is good. It's not like surprising. It's, it's fine. It can run FFMPEG code. You can upload a file, ask it to edit the video file, and it can process the video file and then it can give you the link to download the video file. So it's a general purpose compute platform.[00:01:22] Wow. Did they show how to do this? Agents? I just, I just, I just pinned it. I just, it did I, did I turn into this space? I dunno how to use it. Yeah, it's, it's showing up there. Okay. It can run like is. Is, is, is my And by, by the way hi to people. I, I don't know how to run spaces. I, I not something I normally do.[00:01:42] But You wanna say something? Please request. But yeah, reactions have a look at this video because it run, it generates and runs video editing code. You can upload any arbitrary file. It seems to have good enough compute and memory and file storage. This is not chat anymore, man. I don't know what the hell this is.[00:02:01] What, what is this?[00:02:02] Well, progress has been all faster than I expected. . That's all I can, I, I, I don't know how to respond. . Yeah. It's pretty wild. I wonder, I wonder, I'm wondering how, how this will affect, like opening up the app store different from, let's say Apple App Store when it opened up. Because there are a lot of, of big companies just building stuff already and how like a small developer will be able to, to build something that's not already there.[00:02:31] I dunno. It will be interesting. So one thing that's really nice, have you seen the installation process for the plugins? It's right at the bottom of the blog post and you have to play the video to kind of see it, but literally anybody can write your own plugin. It's a small little json file. It's, it's literally like 10 lines of code.[00:02:49] It's 10 nights of, you described what your plugin does in English, you given an open API spec. That's it. That, that's, that's the plugin. It's amazing. You can distribute your plugin. This is, this is, this is easier than extensions manifest v3, which nobody knows how to use. This is English.[00:03:15] You write English . So, so, yeah. I mean I think, I think I think there'll be a lot of people trying to develop for this if they can get access, which you know, everybody's on a wait list. I, I've, I've signed up to 200 wait lists this week. . I wonder if, if it'll be different if you, if you sign up as a, as a developer or as the chat user.[00:03:35] Hopefully it doesn't matter, right? Use different emails and sign up to both. Let's, let's just see, in fact, use t to generate like, plausible sounding reasons for why you want to build whatever. Cause they don.[00:03:47] But yeah, I mean, how do you compete? I, I don't know, man. You know, it, it's really OpenAI is definitely a partnership strategy to do what they do here which means they're essentially picking favorites. So if you're a competitor of Expedia Kayak Open Table Wolf from Zapier, you're a s**t out of luck, kind of, you know?[00:04:06] Cause these are presumptive winners of their spaces. Right. And it'll happen in too many industries, probably. Right. I was thinking about maybe summarization or, or I don't know, YouTube video summarization, but there seems to be some application of that already on the examples that you shared. Yeah, yeah, yeah.[00:04:26] They have shared that, but I think there's always room to improve the experience. It's just, you know It's interesting which platform, like sort of platform strategy, right? Like if you write an OpenAI chat plugin, you instantly gain access to a hundred million users, right? All of them can instantly use your thing.[00:04:47] Whereas if you are a standalone app or company, good luck trying to able to use OpenAI through you. There's just no point. So you much rather just be on OpenAI platform and promote there. The the fortunate thing is they don't have some kind of like popularity ranking yet. Actually, someone should go open, someone should do register, like OpenAI plugins list.com or something where like everyone can like submit their own opening app plugins and like upload them, review them cuz this like, this is not a complete app store without reviews and a rating system and a reputation system and probably monetization opening app probably doesn't care about that.[00:05:26] But I mean, I can go start that right now. F**k. I can go start it right now.[00:05:34] Yeah, it'll, it'll take a while, right? Like this is the, like the basic version of the, of the app evolving. But this is a pretty basic version. Yeah. The basic version can browse the web, it can write, write an execute code. It can retrieve you know, we can retrieve data from documents, right? So all the documents search just died.[00:06:02] There's like five of these in Y Combinator right now. Oh.[00:06:08] Examples. Pretty crazy how, how they use the FFMPEG library or, I dunno if I'm saying that correctly, but right in there. You don't need to, to write code to,[00:06:27] it's crazy. Dunno. Yeah. Any reactions? Please, please, you know, open space. Anyone can request a speaker. Oh, Ash, come on in. Ash. I have to add you a speaker. Yeah, we're, we're just reacting here. I just, I, I needed a place to talk and I'm in Japan and I don't have anyone else to talk to, so I need, I, I I just want to share this moment.[00:06:46] I think it's a special moment in history. This is the biggest new app source since ever. Yeah. Hey, Shawn. I think plugin is already taken. . Oh man. Someone, someone bought it already. Yep. , of course. Right? Of course. , what are your reactions? What how are you feeling? What's what are you seeing out there?[00:07:07] Just crowdsource all the tweeting. Yeah, man, it's, it's been wild. I mean, I get out of there to like five minutes and then anything drops, you know, , I think productivity today will be like zero. If I, if I still, like, I quit my job you know, a few weeks ago but I would not be working today. There, there's no point.[00:07:26] There's nothing else. There's nothing else that's important, like, nothing's going on. Like this is the only story. Yep. . I wonder if you have any, any frameworks or anyone that's listening any frameworks on, on how you're handling all of this new, new stuff. Like every single day if something new comes up and, or you can like get the, the wait list invitations to, to use the new products.[00:07:52] Q&A: Keeping up with AI[00:07:52] Like, for example, today I just got the, the one from GIK cli and I was just playing around with that. And then suddenly I started to see all of the, these Twitter threads with announcements. It's getting crazy just to follow up with, with the stuff. And every day something new comes up and started. I was starting to feel a lot of formal, you know, like, h how do you keep up with all of these?[00:08:12] Or how do you focus? Does anyone have any, any good frameworks for that? Well, feel free to respond. Also, we, we have some more room if anyone wants to share your feelings. This is a, this is a safe space to share your feelings because. We all dunno how to react right now. I don't know. I just, I, I, I have a few notifications on for OpenAI employees and people that I do that I think do good recaps.[00:08:37] So in other words, find the people who are high signal and who do a lot of gathering of other people's stuff for, and then just subscribe to those people and trust that that is 90% of it and forget the 10%[00:08:57] Alright. And Sean probably, I have, I have another question. So I can't really figure out like what's left for us to do, you know, without AI tools. Like what, what is we learn next? You know, there's no learning some coding stuff, because you can only do that. You know, we can't do arts, we can't do poetry.[00:09:17] Farming[00:09:17] bakery, probably making things with your hands. Enjoying the sun.[00:09:23] Do you guys think this should be regulated? Like you don't go more than like the speed is going? I don't know. I dunno. There's, there's no point. Like if, like, if you regulate OpenAI, then someone else will come along. The secret is out now that you can't do this, and at most you'll slow things down by 10 years.[00:09:44] You called the secret. This is the end. . Yeah. Yeah. I, I don't know. Secret is out. China's trying to do it right, so I don't know if people have seen, but like China was, was fairly strict on crypto, which is probably good for them. And now they're, they're also trying to clamp down on AI stuff, which is funny because oa like they're, you know, the m i t of of China Ihu, I was actually doing like producing like really good bilingual models.[00:10:10] But yeah, they, they seem to be locking this down, so we'll see. We'll see. Right? Like you know, in, in, in sort of the, the free world there, there's open innovation that may be unsafe. OpenAI, try to be safe. You know, there, there's a big part of the blog post that was talk, talking about red team meeting and all that.[00:10:24] I'm sure every one of us skipped it. I skipped it. And then and then we just care about capabilities and now that, you know, every time people have their minds opened, like, I did not know Ron. EG in chat.[00:10:38] Q&A: ChatGPT Intepreter changes Programming[00:10:38] Now that I know my conception of what a REPL is, or literate programming or what a notebook is, is completely blown outta the water, right?[00:10:44] Like there's no like this, this is a new form factor for me. So not now that I know that I won't be innovating on that or trying to, to shape this into something that I can use because I want to use this, and this is, this is clearly better. Does, does this ha have to do with, with the, like AI as backend?[00:11:00] Yeah. Ideas that have been, yeah. You know, GP as backend. So, so apparently I had a few friends reach out to those guys and they're not doing that because it's not mature enough. Like it works for a simple demo. So, so for, for those who don't know ScaleAI did a hackathon I think two months ago just before I did mine.[00:11:18] And the winner on the hackathon was, was something called GPT is all you need for backend. And they actually what in register? DBC is backend.com. But as far as I can tell, they're not gonna start a company based on that because if you even push a little bit, it falls apart, right? So GPT3 wasn't good enough for that.[00:11:36] Maybe GPT4 is maybe GPT5, but then it'll still be super slow and super expensive. Like you don't want to run, you know, a large language model on every API request. So I don't know. I think it'll be good for scaffolding. I think it'll be good for re type use cases. Like, Hey, I need to edit this video on an ad hoc basis.[00:11:53] I don't, I don't want to learn FFMPEG. I don't need to now, because I can just talk to ChatGPT. That makes sense. But if you want a reliable, scalable backend you probably don't want to use it on a large language model, but that's okay because language model can probably help you write it rather than run it.[00:12:13] Hey, Lessio. Hey guys. Oh yeah. Hey guys. What's up? Hey, yeah, we're, we're just, there's no structure. Just drop your reactions. Let's go. Awesome. Awesome, awesome guys.[00:12:26] Q&A: ChatGPT for Education[00:12:26] What do you think what if Shawn, what do you think if you could use you know AI and the education field, like, you know, like personal attribution system for students?[00:12:35] What's the thought automation education or attribution edu edu education. Yeah. That is the holy grail. This is called the Blooms two Sigma problem. Like the, the, the, one of the big issues of education is we have to teach to the slowest person in the class. And, and, you know, I'm a beneficiary of, of a gifted education system where they take out you know, nominally high IQ people and put them in a separate class.[00:12:56] And, and yeah, we did, we did do better. What if we can personalize every student's experience there's, there's some educational theory. This is called Bloom's two Sigma problem. Where the results will be better. I think that we are closer, but like, I still hope that we're pretty far , which sounds like a negative, like why do I want to deny education to students?[00:13:18] Because if we are there, then we will have achieved theory of mind for ai. The AI has a very good model, is able to develop a representation of who you are, is able to develop theories that the test who you are in, in a short amount of time. And I, it's a very dangerous path to, to go down. So I want, I want us to go slowly rather than fast on, on the education front.[00:13:41] Does that make sense? Yeah, definitely. It makes a lot sense and yeah, definitely. I think personally the education for each student and making it turn the best way would be great. And what do you think how about like, first of all, I'm, I'm having very curious, curious question, you know, like we are having, this week was full of launches, so how you guys are keeping up with if we're not, this is, I created the space though cuz I cannot handle it.[00:14:05] Today, today was my breaking point. I was like I don't know what's happening anymore. Yeah, like every single day I'm just in constant anxiety that like everything I assumed about the world is gonna be thrown up. Like I don't know how to handle it. This is a therapy session, so feel free to express.[00:14:21] Definitely. It's, it's been a very overwhelming feeling for everyone of us like that. I think, you know, like past two weeks and like the industry was definitely a lot, lot of ones we are definitely open for, you know, to discuss more about it. Thanks a lot for this space. Sean. Yeah. Appreciate. Yeah. Va one more thing.[00:14:39] So I think that the most constrained version of education use cases is language teaching. So there are a few language teachers out there speak I think is one of them that is an OpenAI partner. And they're also part of the chat GPT plugin release. , but there are also other language tutor platforms.[00:14:57] You can certainly have your news. There was one that was released maybe like four or five months ago that you can try to see what the experience is like. And you can, you can tell when the teacher has no idea who you are and it breaks the illusion that you're speaking to another human. So I, I just, you can experience that today and, and decipher yourself if we're ready for that.[00:15:14] I hope that we're not ready and it seems like we're not ready. Yeah, definitely, definitely. Thanks a lot for sharing. And guys, what do you think?[00:15:19] Q&A: GPT4 Sketch to Website Demo[00:15:19] Like I, in the launch of four we have show that we could, you know, generate apps and web apps just from you know, like a single simple sketch, you know different tent.[00:15:30] Just start from sketch. So what do you think like how, how it would be impacting the industry? It's all because it's not just like that, that sketch was very, was a very shitty sketch. Right. It was just like drawn on a piece of paper. But if you combine that with the multimodal, like it was that they had another part of that demo where they had a screenshot of the discord the opening eye discord and you're mm-hmm.[00:15:57] and they put it in and it, it like read the entire screen to you and if you can read the entire screen, you can code the entire . Screen. So it's over like[00:16:12] It's definitely, I think interaction, interaction designers, you know, like people who like, think design function still have some time. Yeah. I, I just, I just, I just tried the same thing, you know on bar today and it was like much more better than GPT3 so definitely it's you know, things are really changing.[00:16:30] Q&A: AI Competition and Human Jobs[00:16:30] Great forward. I'm, I'm really worried what we wanna do, you know? Do you think the competition will like stable everything? Like what competition? Anthropic. Well, like Google, Google won't race, I don't think. Google Race, like Google the fight. The one that, the one that launched the W links list of blog posts.[00:16:50] That, that Google.[00:16:55] Well, no, not, not the list. Not the list. Competitions will come. . I have a question. I mean I mean my fear is many of the jobs that are going away, whether it is developer and designers, because I mean, I think GPT four is very capable. So how to deal with it. I mean, it's going to replace, I mean, many of the jobs, that's for sure.[00:17:16] Yeah. It's okay. We'll find new jobs or we'll, we'll not need jobs anymore. We should, we should also, Start universal basic income. That's, that, that is something I, I do believe, yeah, I think the, the main change is going from the web of like, syntax to like the web of Symantec. So if your job is valuable because, you know, a unique syntax or like, you know, how to transform things from like words to syntax, I think that will be a lot less useful going forward.[00:17:45] But the Symantec piece is still important. So a lot of product work, it's not just writing CSS and HTML and like the backend for it. It's a lot more than that. So I just thinking about how do you change your skills to do that. But yeah, even the sketch, you know, you gotta like, you gotta draw the sketch and to draw the sketch, you gotta know where the button should go.[00:18:06] You know, you have, you know, incorrect with it. Yeah. I'm just processing this as I, I just read the whole thing as well. And Yeah, I mean, it's been a wild wild couple of weeks and it's gotten me thinking that maybe all our role was over the past couple years was we were just middlemen to talk to computers, right?[00:18:27] So we're sitting in between, it's over man PMs or business folks or whoever wanna build a product. And then as a software developer, you're just a middle manish talking to the machine and it seems like. N LP is the way forward and, oh, yeah. Yeah. It's, it's been it's been, it's been a while.[00:18:42] ChatGPT Plugins as App Store[00:18:42] Couple of weeks. It's, I feel like we all just have to move either move upstream or, or find other jobs. You just gotta move upstream, either toward product directly. Cuz right now the plugin is yeah, is, is just you know, it's still a very sanitized UI that is controlled by OpenAI. But imagine them opening up the ui portion as well.[00:19:03] So you no longer need to have a siloed product that needs to integrate. ChatGPT instead you can bring your product directly into into ChatGPT, I don't think exactly. I think that would be probably the next next logical move after this, and I'm sure they're already thinking about that.[00:19:22] So that's a great, I don't know if this is, it's wild. What are you guys think? Yeah. Yeah. Like, so before you came up, right, I was, I was talking about this like ChatGPT has at least a hundred million users. Why would you bring people to your platform rather than write a plugin for ChatGPT and use their platform?[00:19:39] It's an open question now. Zapier just launched their integration. OpenAI and OpenAI just launched their integration of Zapier. Which one is gonna be more interesting? Probably OpenAI.[00:19:50] Totally a hundred percent . this is the app store of wow, our century of our decade. Like, I don't know, maybe century. I, I think the thing with ster though, if you think about it, like how many native apps do you download every week, every month versus like how many web things you use. So I think it's all about whether or not long-term opening eyes incentivize to keep broadening the things you can do within the plugin space.[00:20:17] And I think the lab, you know, as this technology gets more widespread, they're gonna have a lot more pressure from regulators, safety, blah, blah, blah. So I'm really curious to see you know, all, all the, all the government stuff that they'll, they'll have a congressional on this in six months and by then it will be completely irrelevant.[00:20:34] It's like that beside that time, they, they, they called it the GameStop guy after he made like 20 million on GameStop. And he just, you know, he was like, yeah, you know, followed the rules, made a bunch of money for those who don't know, unless you're our co-host. On the, we were supposed to drop an episode today, which I was supposed to work on, and then Chatty Phi dropped this thing, and now I, I can't think about anything else.[00:20:59] So this, this is my excuse for not, for for not working on the podcast today. . I know it's funny, we have like three, four recorded ones and spend last week, like GP four came out and we're like, okay, everybody's talking about this is irrelevant. What else? Anything else? Like, but I'm really excited about the, I, I feel like the first, the first use case for this, and I think he tweeted it about it too, is like, before if you had to do like data reformatting and stuff like that, it was really hard to do programmatically.[00:21:32] You know, like you didn't have an natural language interface and now you have it. And before if you had to integrate things together, like you could explain it very easily, but you couldn't like, put the APIs together and now they kind of remove all that part. So I'm excited to see what this looks like.[00:21:48] For commercial use cases, you know, you could see like, is there gonna be like a collaborative ChatGPT where like you're gonna have two, three people in the same conversation working on things. I think there's a lot of ui things that will improve. And so as we have lining from OpenAI for a second, almost pulled them up, but I'm sure you cannot talk about it[00:22:07] But yeah, it'll be interesting to see. Yes, sir. We're extremely excited. Extremely excited. I, I don't, if you, I don't know what else I'm, I'm like, so as far as I can tell there's the, there's hacker and Twitter. I haven't looked at Reddit yet, but I'm sure there's a bunch of reactions on Reddit.[00:22:23] I'm sure there's the OpenAI discord that we can also check out. I got locked out of the discord at some point, but yeah, anyone, anyone else like see news, demos, tweets the whole point of this is that it's live, so please feel free to share on comments or anything like that. But yeah. Yeah, the, the craziest thing I saw was the Mitchell from Hash.[00:22:44] We tweeted about Yes. How the integrations actually work and you just write a open APIs back and then just use natural language to describe what it's supposed to do. And then their model does everything. I wonder if they're using the off-the-shelf model or they have like a fine tune model to actually run integrations.[00:23:02] I wonder, I don't think they'll ever say it. Knowing them, probably they would just use the base one cuz they want, like, I think opening eyes kind of wants a God model, right? There's no point. It's not intellectually interesting to do small models, but like, like it's trivial. Yeah. Yeah. It's, this is a minor optimization problem as far as the, the long arc of history and the, the point is to build a gi safe agi and I, I do think this is kind of safe, right?[00:23:33] Like, . One of the criticisms that people were saying on hacks was that this is very closed. Like it's, it is an app store. At any point opening, I can randomly decide to close this like they did for Codex, and then they change their minds. Whereas if you use something like Alan Chain, it is more open and something that at the same time, like clearly this is a better integration path than long-chain.[00:23:56] Like, I much rather write this kind of plugin than a long-chain plugin. So they, they've managed to, I mean, they know how to ship man, like they're an AI research lab, but they also know how to ship product. Mm-hmm. . Yeah. I, I'm curious to see what the pricing models gonna look like. Also, I mean, if I'm writing the plugin, this is great because I don't even have to take care of the compute, you know, like, I just plug it in, then they actually run everything for me.[00:24:26] Yeah, but how, how it'll be monetized. I mean if the is giving their plugin know Expedia, I mean, people will not go to their website. Yeah. I don't, I mean, yeah. I have no idea that they, I don't think they said also don't super care . Yeah. It's because in the, in the app store, it's transaction driven.[00:24:46] But on Channel G, you're just paying a flat fee every month. So like, you can't really do revenue share on a flat fee. And I don't think that we use like, the Spotify model, but it's like a why not the amount of times? No, wait, wait, wait, wait, wait. Why not , you have Spotify. I just, Spotify model works. Cause swyx has power, right?[00:25:05] Opening has power. Same thing. They have all the audience. Yeah. But every, every every song is like the same value. Like if you listen to song actor to song y. , like, you're gonna make the same money. Like if I'm calling the API to, for like the meme generator or if I'm calling the API for the, you know, business summary thing, they're probably gonna cost the firm things, you know, so it's kind of hard to model up for OpenAI to say, Hey, okay, we're charging, we're going from 20 to 35 bucks a month.[00:25:36] But then like, how do you actually do royalties on a per model basis? Like how do people decide what royalties to negotiate? This probably needs to be a flat fee, but I dunno. Or put your credit card it OpenAI and then every time you wanna use a plugin, you pay for it separately. Uvp, usage based pricing all the way, and then you just get at the end of every month.[00:25:58] Exactly the, the only question mark is like, how much does OpenAI value the training they on and like how much they wanna subsidize the usage. Canada they have, they have promised to not use any of our usage data for training. So, oh, but the, I think like the plugins, it's a, it's a different thing.[00:26:16] It's like, like how you could, you could easily see how are like requests usually structure for like these things, you know, like, are people searching? So how are people searching for flights and stuff like that. I don't know. I haven't read the terms for like the actual plugin, you know, so. Well if anyone has please come up to speak cuz we're all processing this live.[00:26:37] This is the therapy session. Yeah, go ahead. One thing I see is basically you have to change the plugin I mean, to ask anything or even if you did browsing, right? I mean I see. I mean, they are becoming directly competitor to Microsoft also, I think, because now a user can actually just see, I mean, instead of being chat or Google, I mean they, they just.[00:27:04] Basically select the browsing plugin and basically get all the updated data. And other thing I see is basically you have to change the plugins. Like if you want to use the Expedia data, I don't know how it'll fit with the browsing plugin or you can select multiple plugins. But yeah, it is interesting.[00:27:23] I mean, if we get access, yeah, there is no actual browsing plugin. The browsing is a new model. So just like you can select GT three, GT 3 45, GT four, there's a new model now that says browsing alpha. So you, you can use CHATT in browsing mode and then you can use it in plugins mode, which which is a different model again.[00:27:45] So the, the plug browsing don't cross over.[00:27:51] Oh, that's interesting. And how do you see, I mean, in this whole descending, they are becoming competitive to Microsoft or how they're playing it out. I mean, Bing is just by the way, like, yeah, this, this killed the bing wait list. Cuz you don't need to wait for Bing. You can just use the browser mode open of Chatt.[00:28:11] How does it compete? It competes for sure. I don't think Microsoft cares. I don't think OpenAI cares. This is one of those things where like, you know, they are the two, two friends, you know, and they're clearly winning, so who cares? I don't like, I don't imagine it takes any of their mental bandwidth at all.[00:28:29] Yeah. The main thing is Google is Yeah, the main, like how is Google competing? Well let's see. Right. Bard is out there. I haven't got us yet, but could be interesting. Again, like it doesn't seem like they have the shipping capacity or velocity of Open I Microsoft and. That is probably going to bite them eventually because there's already been a big brain drain.[00:28:53] Something like four researchers, four, the top Google Brain researchers left Google Brain for OpenAI in January. And you know, those are the ones that I know about. And I, I imagine there's, there's quite a bit of brain, brain drain and firing going on at Google, so who knows.[00:29:08] All right, well, any other topics, concerns? Hyperventilation, if you just wanna scream I can turn down the volume and you can just, ah, for like five minutes. , that was literally, I was like, I, I need to like scream and just, ah, because what is going on?[00:29:29] I said that I'm filling out the form right now for the Oh, yeah. Okay. So wait list. So use use chat t to fill out that form. Right. And then, and then use a fake, use a different email and fill out the form a different way. This maximizes . I'm going to ask GT for what plugin do I want to build or, right, right.[00:29:51] Exactly. Yeah. Yeah. I, we can brainstorm. My plugins can live. Yeah. I think that will be a fun exercise. Like the, the main thing that breaks my brain is just this, this whole ability to run code, right? Like this is a new notebook, a new ripple. Mm-hmm. It, it looks like it has storage and it has memory.[00:30:08] Probably it has GPUs. That, I mean, can we run Lama inside GP?[00:30:19] I don't know if that's a, a model within a model. I think for me, most of the things come to like, you know, if I have my own personal assistant, what I want the assistant to do. I think like travel is like the first thing that comes to mind. Like, if I could use pt Yeah. Expedia, plug in with my calendar.[00:30:39] Yeah, yeah, yeah, yeah. But it needs to like know where I, where I'm supposed to be going to, you know, like if I just add a calendar that's like I'm going to, you know, room this week. Yeah. And then like can automatically both send my calendar and say, okay, these are like, or like the times that you like to travel, I know that you don't like ops and yada yada, yada.[00:31:00] That's one thing that I've always, we had this thesis at my peers firm about personalized consumer. There's so many website like, . I go to a lot of basketball games and every time I open Ticketmaster or whatever, it always shows me that she's a seat. And like, I'm not gonna see, that's not what I, that's not the tickets I wanna buy, you know?[00:31:18] But doesn't matter how many tickets I buy, never remembers that. So I think a way to say, to see, take all the information in and suggest, Hey, I saw that there's actually a price drop for the specific seats that you want, not for like any seats. You know, I think that would be a, a very good use case. So I've been a personal entertainment assistant for like, travel like going to shows, going to games.[00:31:41] That would be cool. That's what I'll submit on the wait list. Then we'll see if anybody cares. Right. Did you see get Lindy? Yeah. Yeah. At the, maybe you wanna recap, get Lindy for people. I'm gonna pin it up on the. . Yeah. So basically and this is like the kind of like a assistant lend the ai, right?[00:32:03] Yeah. Lend the ai it's on the board right now. Yeah. For those who can see it through the space. Yeah. Yeah. Actually at the AI Thinkers meet up the, the other day, you can basically like create all kind of like personal workflows and you, it kind of looks like integrations like zier, but it's actually just natural language.[00:32:24] So you can pop this thing up on your desktop and say, trying to hire 10 software engineers. So go on LinkedIn and plan 10 software engineers. The next step, draft a, an email that says, I'm the CEO of this company and I'm trying to hire for my team. If you wanna talk. Then the next step is like, send emails to all these people and it's gonna use people data labs or something else that they use on the backend to get the emails.[00:32:50] Then it actually sends the emails and. This is just gonna run in the background as if it was like you actually doing it. It's pretty neat that you don't have to write the actual integrations. Like it just uses natural language so you're not bound by what they build. Like theoretically anything you wanna integrate with, you can just explain to it how it works and it's gonna figure out how to do it.[00:33:12] So there's a wait list now. Flow didn't give us any papers just because we were at the meetup, so I'm also waiting to get access to it, but it looks really, really good. Yeah, so generative AI's top use case is generating wait lists, right? Like we we're, we are, so we have never had such an easy way to generate a lot of wait lists.[00:33:30] A lot of signup for witness. Oh my God. So much interest. So much product market fit. But also you know, one thing that you, you raising this point? I think, I think, I think by the way, I also pin this up. Mindy can support complex roles like no meetings on Fridays, all one-on-ones on Monday. , I like my meetings back to back within five minutes.[00:33:47] Five minutes in between. So it's just arbitrary rules that you could not program in a normal assistant type environment without a large language model. Which is kind of exactly what you want when you're booking your travel, right? Like, hey, I only like aisle seats unless it's it's a flight that is less than one hour that I don't care, right?[00:34:02] Mm-hmm. . So stuff like that I think is, is super interesting. And but also like not a common use case. Like how many times do you travel a year? Like, you know, five, right? Like more than that, but yes, I think for, yeah, a lot of times it's not a, it's not like a super widespread thing, especially if you don't do it or work.[00:34:21] If it's infrequent, you want high value and then if it's, if it's frequents, you can do low value, right? Like that, that's the sort of binary tradeoff, like the Uber is sort of frequent and low value. Airbnb is high value in frequent there's something of that nature. . So like, you want, you want sort of inspections of that sort.[00:34:37] Google vs ChatGPT[00:34:37] But the other thing that you brought to my attention was, and, and has room for Google to do something is do you notice that OpenAI plugins, none of them are Google because they're not friends. So Open BT will probably never have first party access to Google Calendar, probably never your Gmail and probably whatever, you know, Google copies, OpenAI again.[00:35:04] They will do, Hey, we have all your docs.[00:35:10] Yeah, I, I, I'm interested in that because I don't know if you remember, but like in the first iPhone, like YouTube came, like pre-installed on the homepage and then I forgot when, but one of the early ioss, they removed it. So now obviously Google's not a friend. Who's gonna be a friend in the future, who's not gonna be like, do we all have to hail our AI overlords?[00:35:33] Yeah. To get access to the, the only plugin system. Yeah. The only winners are brown CEOs. Think you're fine. Alright. But yeah, yeah. I just invited nada. C my old boss. Hi. You can't lurk. I, I want, I want to hear from you. And but, but also, you know, yeah, I, I think the Google point is actually novel.[00:35:50] I'll probably write something about that. Yeah. I mean, I'll have to write something about this today. So please feed me things to write.[00:36:01] Nader Dabit on Selling His GPT App[00:36:01] Oh, there we go. Hey, what's up man? What are you think. I know it's like, not entirely your space, but like you're, you're all about the future, right? I mean I did build and sell an AI company about a month ago, . I did the wait, what travel app was built on GP T three Tweeted about You sold it? Yeah.[00:36:21] It was getting like a hundred thousand visitors a day, like 60 to 80,000 unique a day. And then I, whoa. Yeah, I sold it like within about 24 hours. I tweeted out that it was for sale. I had like 30 or 40 people in my inbox. Whoa, whoa, whoa, whoa. Okay. I need, so like, but you're right. This isn't my, my man like domain of expertise.[00:36:41] It's fine. You make, you may just a thousand dollars on the side. It's, it's cool. Wait, wait. So I saw you tweet your original thing, which was, Hey you know, GP three can plan your travel. I don't know what happened since then. Can you, can you fill the rest of. Yeah. Yeah. So I mean I was basically, you know, I travel a lot for work.[00:36:55] I, I do travel like once a month and, you know, but I'm also very resource constrained on my time. So I usually like to spend like one day sightseeing. So what I typically do is I go a trip advisor and then I kind of like, you know, Google around and like look at all these things and it usually takes me about an hour to figure out like what I wanna do on my day or two off to go, like sighting.[00:37:14] And then I realized GPT3, you know, you can just literally ask and, and say, okay, within X number of. Like, I'm gonna be in this city, I want to have an iter itinerary. You know, you can give all these different parameters and it gives back a really good response. This was before GPT, even three and a half or four was out.[00:37:30] So I just built like a nice UI on top. Then, like I mapped over the results and, and was linking to, you know, the the Google searches for these different items and, and kind of made it into a nice user interface and, you know, just built it out and tweeted it out. And it, it just got a lot of traction and attention.[00:37:48] Like I said, I had around a hundred thousand visitors a day, like right off the bat, 60,000 uniques like per day. So it was getting a shitload of of traction and. I don't have a lot of free time to kind of like, maintain or build something like that out. So it was costing me money, but I wasn't monetizing it.[00:38:06] So the way that I was thinking to monetize it would be to use affiliate links and stuff like that. So I could either, you know, spend time figuring out a way to monetize it or just try to make, flip it and just make some money. So I decided to sell it and that was kind of it. I just sent a tweet out and kind of said, this is for sale, who wants it?[00:38:25] And I had I had so much inbound from that that I had to delete the tweet within about two hours cuz I was just unable to keep up with all the people that were coming in. And I filled it out a couple of offers and I, I found the person with the most money that could close within the shortest amount of time and just took it.[00:38:44] Well done. Well done. Nice. Awesome. I need a, I need a, I need an applause button right here. . Okay. So with that context your thoughts on today, what you seeing? There's Expedia there, but. Comment on travel or not travel, whatever you want. . Yeah, I'm still reading up on the, the chat plugins actually.[00:39:01] And I was hoping to kind of chime into this to learn a little more about how they work. I'm here on the the page. I've had API access from fairly early on. I signed up and I've been you using it a lot. I'm trying to find some different ways to integrate AI and machine learning into the blockchain space.[00:39:20] There's a lot of stuff around civil resistance that I think are gonna be, you know, pretty interesting use cases for us. It's obviously not like a, a a type of use case that is gonna be useful to, to the general public maybe, but yeah, I'm still, actually still trying to understand how these plugins work.[00:39:35] So what have you seen the developer documentation, which developer documentation at the bottom? Yes. That's where I'm, I'm check, I'm reading through as of now, I see the examples, which are pretty cool. Yeah. Yeah. So my, my quote the, the quote I put on Hacker News was, this is OpenAI leveraging chat, GPT to write OpenAI op open API to extend OpenAI chat.[00:39:58] GPT. I'm confused, but it sounds sick, but yeah, I mean, so open api, you know, not to be confused is OpenAI is randomly the perfect spec for OpenAI to navigate because it, you know, is somewhat plain English. And then you just supply a description for model. You described a off method. So they actually provided a link to a repo where you can see some examples.[00:40:20] The examples are not very, not very flesh out. But you can do, like, bear off, I assume you can do whatever, whatever kind of off you like then you just provide like logo url, legal info url. It's not, it's not, it's not that much. This is 10 times better than Chrome manifest.[00:40:37] Like manifest v3. Yeah, I mean, I'm reading through some of these examples and a lot of them are in Python. I wish they would've more JavaScript stuff, but I would say 10 times would be kind of an understatement if I'm understanding how some of this stuff is gonna work. English is all you need, man.[00:40:53] English is all you need.[00:40:57] Well, so, so, and then I think in buried in the video is sort of the Ethan experience, right? Which is where you specify. So if you're, if you're first party congrats, you know, you're, you're inside of the the chatt ui, but if you're third party, you can just host your Js o file anywhere. It's literally a JSON file on an API spec, right?[00:41:15] You hosted Jason file anywhere. And then you just like plug it into their their, their text field here and then they, they validate a little bit and it's installed. So there is a third party app store on day one. Yeah, that open table plugin example is pretty sick. Yeah. So like yeah, I I What would you want as a developer that's missing?[00:41:41] I think that we're like in the golden age of of being a developer and I don't know if it's gonna go downhill quickly or if it's gonna go like, get better quickly or this is like the, the end of all of it. like, is OpenAI just gonna be where like we do everything like nothing else is like gonna exist.[00:42:00] I think that Okay. You know what I, I know that's not the answer for sure. I'm just kind of joking, but I think it will, this is obviously shut down a lot of companies. This is the app store moment, right? For like, just like, I mean, you and I remember the iPhone app store moment. Some people dropped everything to write apps and they made it big and some, a lot of people did not.[00:42:20] But the people who were earlier rather than later probably benefited from understanding the platform. Like imagine, imagine you, like, you know, you, you are a big React native person for a long while. Like imagine if you had the chance to drop everything and be one of the first developers on a new app store.[00:42:35] Like that's pretty huge. Yeah, a hundred percent. But I'm wondering like the, the type of mode that you'll be able to build with some of this stuff, because it seems like that OpenAI AI will just continue adding more and more features directly into the platform. But I think like for very like, Proprietary type of stuff.[00:42:54] It might make more sense, but like if you, if you want to build like an app for the general public it just seems like they'll end up integrating something like directly within their platform for a lot of different ideas like, such as this travel app that I sold. I have a feeling like they'll have a way better version of that built directly into their platform sometime soon.[00:43:13] Q&A: ChatGPT Waitlist and Voice[00:43:13] Hey, hey guys. Can I ask just to get a quick update does anyone here have access to it yet? Like is it, is it open? Cause I signed up for the wait list, but I haven't seen anything yet. Yeah, no, it's just, it's just wait list where just like 90% of the stuff that people launch, you know, she has a few, she has a few videos and demos, but yeah, it's just a wait list.[00:43:31] Who knows? I mean, thanks. Opening OpenAI Pretty has been pretty good about getting people off wait list, right? Like a lot of people got off the GT four API wait list, like the day after they launched. Mm-hmm. . This one, I feel like they're quite fully baked, like it's. I wouldn't be surprised if they started dropping tomorrow.[00:43:50] So we'll see. But like you can start developing your, your third party plugins today, because there's examples. The docs are like two paragraphs, but that's all I need really . So, so I've been, I've been working and, and I've been following a lot of projects where people are, the one thing I don't see with ChatGPT is like, why are they have, we have Whisper, we have the APIs for ChatGPT.[00:44:13] It's like, why are we not at the point where we're talking to this thing and it's talking back to us? Like, I don't know how we haven't, nobody's wrapped their head around that yet, but it's like, it seems to me like, don't you wanna be like, Hey computer build me an app that does X and it says okay and builds it for you and talks back to you.[00:44:29] Like, I just, it's like, I don't know. That'll be the first probably plugin that I try to work on, but it's just driving me a little nuts. That's all interesting. I like the voice interfaces because sometimes it gets really long, like some of the prompts get really long. They're like, I don't wanna talk that long.[00:44:46] Yeah, yeah. Yeah. I was so, so I was doing, I was messing with the system prompt, basically get it to be like, Hey look, I'm gonna be talking to you. So keep it condensed. I think like the ideal interface would be like, for like, talking to, it would be like putting that at like the system level, but also, you know, being able to type as well as speak to it is just something that I'm, I'm trying to work on.[00:45:08] And I think with Plug, you know, if we could do that with plugins, I'd be huge. Cuz I know there's already a, like a Chrome extension that allows you to talk to it. Or, or I guess you could do it natively as well, but, you know, native stuff on like iPhone and Android is not too good.[00:45:24] LangChain with Human in the Loop[00:45:24] Hey, you, you mentioned that. Hi, by the way. You mentioned the hey way of, of talking to or having way the AI talking to you as a user. So just today there was a new release to of LangChain. I know it's kind of, not really the plugin, but this is the closest thing probably. And they edit a Ask Human tool.[00:45:46] So now the model can ask you a question if it's not sure. About something[00:45:55] to share. Share what? Go ahead. So, so the ask you if it's during its chain of thought, when it's not sure. To an example. Right, right. Oh, I would love that. Yeah. Probably not gonna do that. It's too confident. Yeah, I, I've seen a little bit about. LangChain, but I haven't used it yet. Has anyone here it?[00:46:15] Oh, it's all about it.[00:46:19] I did, I did. I built the LangChain on UI too. It's pretty nice. I mean, especially when it first came out, the, the trolling, it was like so rudimentary. But it's nice to be able to change things together. I think the agent part is pretty interesting. I haven't used it myself because I didn't need it.[00:46:34] But yeah, there's a, a very big community. See, see, light chain was very smart, right? Like they picked out the open source angle first, and then the others like dust or did the closed source angle. Now they have indirect competition with ChatGPT, but Langchain still has that. It's open source, extensible, like you own your agent.[00:46:55] Google vs Microsoft vs Apple[00:46:55] Them doing business deals with OpenAI in, in closed doors, right? Like, so pretty smart, like strategic position. All things considered.[00:47:05] It's a little, isn't it? It's like a little funny to me. That, you know, it's like goo because Google just came out with Bard, right. And I don't know if you guys have messed with Bard at all, but it's at least to me another wait list. Oh, okay. Yeah. I mean, to me it was a little underwhelming. I mean, I'm, I don't know if you've seen like the same, yeah, if you've seen like the screenshots going around, like it seems like, you know, someone tweeted it was like in, in guys in a boardroom or whoever's in a boardroom just being like, s**t.[00:47:30] Like, we need to you know, we lost our first mover advantage here. But it's just kind of funny to me that like, I guess now Microsoft's gonna have like an app store, right? Like just after everything, you know, Microsoft dominated in the nineties and stuff, and then it was Apple, apple, apple. But it's just kind of funny to me that it's gonna be, I guess Microsoft now, right?[00:47:49] Bard feels like Bing does to Google. Totally. Yeah. A hundred percent. I agree with you a hundred percent. All the turntables, right?[00:47:57] Yeah. So for, for those of you who might have missed the earlier discussion the one thing that OpenAI or Microsoft will not do is integrate with your Google calendar. So, the one saving grace that Google probably has it, it probably owns your workspace, right? Like most of us have Google accounts, Gmail accounts.[00:48:14] When we work, we log into Gmail and Google, again, use Google Docs spreadsheets. So if Bard is smart, they will take advantage of that. And then slowly watch as everyone moves to Microsoft Office.[00:48:31] I think Apple should do a partnership with the OpenAI and basically Microsoft. Cause Google has huge advantage of Android. So basically having OpenAI on the, I, I mean, it would I mean having the partnership with OpenAI would make, I mean, very useful on I devices if they, I mean, Siri is really bad and if they integrate with I, I mean they've win the world I think.[00:49:00] So it would be huge, beneficial to Apple and basically the Microsoft also if they integrate together because Microsoft doesn't have any of the devices and most people, I, most ordinary people use the devices iPhone or phone and . So it would be huge advantage. And for the 10, basically Apple I, I'm very curious to see what Apple ships next.[00:49:24] You know, everyone's shipping AI stuff and then Apple was like, Hey, look at our AR glasses. . Yeah, but I mean, ar ar with, with the, with the 3D models that are, that are coming out cuz isn't it mid journeys working on like a three, like their lab, I know is, is building a 3d generative model. And I think that sort of stuff with, with AR is very, oh, is that, is that public?[00:49:45] How did, how did you know that? I don't know if it's public. I, I saw a tweet about it I don't know, like a week ago. It is a semi, semi open secret in San Francisco, but I, I don't know if it's public. Yeah, I think I, I saw them, it was some context of they were talking about text to video and they were like, well we're, we're doing our like 3D modeling first.[00:50:02] So, I mean, my assumption is, and I, I don't work in the space yet, unless anyone's hiring please, I'm looking for work. But it seems to me like Apple. Seems to have their head on straight and like it might be that if they're gonna release these ar like mixed reality ar vr glasses, like, you know, the mo the thing that makes the most sense to me is like getting with generative AI graffiti modeling.[00:50:24] It's like, you know, it would be cool to go to like a coffee house or a bar. And then, you know, when you see like the graffiti in the bathroom when people write sometimes funny stuff, sometimes, like the worst stuff you've ever read in your life and you're like, what is going on when this person's going to the bathroom where they have this much hate?[00:50:38] But it's like, it would be cool to have a component of that, you know, like in the metaverse, so to speak, right? Like, so you put on your AR glasses and it's like, oh cool, I can see like a bulletin board here that exists in the fizzled. But it's also in the, you know, it's like augmented, right? That's just, to me it seems to be like the logical next step.[00:50:57] Interesting. Well, we'll, we'll see that when that happens. I recently got a Quest Pro quest to my, and yeah, my parents love it. And any tech, any type that my parents like, I think has a real crossover appeal. You know, the thing that you, your conversation had gimme an idea for winners of every app store in the early days, like Facebook has an app store, apple had an app store, you know, the winners of an app, store games like what we need Yep.[00:51:24] Is a multi-player. Like everyone logging into chat, BT and then playing a multiplayer game line. Mpc. MPCs are gonna text you on your. , that would be kind of cool.[00:51:40] ChatGPT Plugin Ideas[00:51:40] Actually. I was thinking, I don't, I don't know if it's gonna be game games at first though. Like, it seems like games always push the envelope with tech.[00:51:47] Well, it's like pornography and games, right? But like, I don't know, I was talking to like, you, you mentioned your parents and like you know, I was talking to my mom about this stuff and I was like, you know, I'm seeing stuff that are just demos of just like, Hey, take a picture of your fridge and it'll tell you like, here's what you can make.[00:52:01] Or you know, even like talking to it and just being like, Hey, here's what I ate today. You know, what's my, how many calories I ate today? Or, you know, what's my diet plan? Just things like that. And that's why I brought up the talking to it just with na using natural language and then having it, being able to talk back to you.[00:52:17] I'm surpri I'm like really surprised that they haven't implemented that yet. Cuz it seems to me like that's a use case that a lot of people would use it for, you know? Or if you could just like, you know, call it on a phone if you built like a Twilio back in, into it or something. Like I just don't, it, it boggles my mind why they haven't.[00:52:35] Put that feature in yet? . Yeah. Yeah. I really don't think it's gonna be too long before you're, you're sitting there at work and you get a text or call on your phone from an nbc, Hey, our village is burning down. You need to come over here and help . Do, do you guys think there's gonna be different silos?[00:52:55] Like you know, with Bard coming out and you know, people implementing GP T three and four now, I guess, into all their apps, but do you think they'll be like, chat GP p chat, GP, PT will have their store and then Google will have their store? Do you think it'll be like, there's gonna be a clear Victor here and then, you know, it'll be like, okay, Google's apps or, you know, Google Docs or whatever is like part of chat GP t's plugins, right.[00:53:20] Yeah, it is gonna be like crypto. Everybody's just gonna be fighting for the top. You're gonna have the couple of dominant people, but then you're gonna have all the, the small guys who go up and down and Yeah, I I, I feel like it's gonna be pretty similar to, to how crypto was. So we're gonna have some slur juices is what you're telling me.[00:53:41] Yeah, boy. Nice, nice. I dig it.[00:53:46] Not an app store?[00:53:46] So may maybe we aren't, tell me what you guys think about this, cuz maybe we aren't thinking about this right? Because maybe this is not an app store. Cuz typically in an app store you'll go ahead and choose which plugins you want installed, like on a phone or whatever have you.[00:54:02] But the path forward seems like all the plugins are like omnipresent. I, I don't know why Google isn't shitting their, shitting their pants right now. Cuz basically you check like openly I could just force all. The big companies to write plugins and then just be a single search box for everything. So imagine if you wanna like fly somewhere or you wanna book a hotel you, we have the Expedia and booking.com.[00:54:29] Both of those plugins summoned up and it shows you both the results. And then you can click through on whichever ones you want. And then, yeah, you charge 'em based on click throughs. Like I, I think like we're, maybe we're just getting tripped over by the fact that you have to choose a plugin right now and only interact with that single plugin.[00:54:49] But I think I think the smart move forward would probably be just to have all of them omnipresent and then have this like n l p higher layer up there to summon the right plugin when need be. What, what do you guys think about that? Yeah, so, so that's like the LangChain thing. That's what I haven't used LangChain yet, but it sounds like that's, from what I was reading with LangChain, it sounds like that's kind of is how I thought that worked.[00:55:12] But I don't know, can someone here like enlighten me? I, I don't know if it, how, how LangChain works.[00:55:21] LangChain and the Future of AI[00:55:21] Yeah. I don't know how LangChain works either, but I think it's gonna be a two-way street. Everybody's gonna be making plug-ins with chat GP p t and everybody's gonna be making chat GP plug-ins for other services as well. I think there's gonna be a whole bunch of people about to make a bunch of Jira plugins and stuff like that, so I think it's kind of gonna be a, a two-way street.[00:55:45] I dunno, is anyone else, like, this is super exciting to me. I haven't been this excited about like, the internet since like, probably like the, like the web 1.0 days. Like I, I, I hate, I'm so . Yeah. Like, I hate web two. Like, this is cool. I'm glad that like spaces exist, but I hate Web 2.0, like Web 3.0. I'm about, and like, I, I consider this part of Web 3.0.[00:56:04] But it's exciting, right? Like, this is cool. Like I, I'm really, you know, I'm stoked about, about the progress that's being, like, the joke is like, you know, every day in, in AI is like, it's like way longer, right? It's like we're telescoping very quickly. Yeah, I mean, one of the things, telescope and updating.[00:56:23] Yeah. You know, I, I would say I noticed towards, maybe like three years ago when I was working at aws, it just seemed like for, for about five or or so years, everything was very stagnant and there just wasn't a lot of exciting things that were happening. Everyone was like, if you remember, all the Devrel advocates were like all creating like tutorials around creating your own CMS and your blog, and you saw like that exact same tutorial given by like hundreds of people over the course of a few years because there just wasn't any cool s**t that was happening.[00:56:52] And then I think when crypto and, and blockchain stuff like that kind of caught my attention. Caught my attention, and I'm still excited by that, that stuff. And then this seems to be just almost like when, if you were like around when the iPhone was coming out and actually realized how important it was, I think everyone now is, is seeing this and they're all like realizing how important it is.[00:57:13] And it's cool to be like part of this moment as a software engineer. Yeah, I'm, yeah, go ahead. Oh, sorry. I was gonna say, like, I'm, I'm excited for you, I'm sure you guys saw the alpaca stuff, right? And I know that they're doing D D M C A stuff, but essentially someone's gonna train one of these models and it's gonna, you know, you're gonna be able to run this stuff offline.[00:57:35] And just like the way to, if, if you have access to like I forget which one of the EAC accelerate people was talking about it, but it was like wharf in the flask. It's like you've gotten the machine offline. So if you don't need internet access to access, like, the entirety of human knowledge, whatever's in the data set up until 2021 or whatever, and you don't need internet access, like that's gonna revolutionize everything.[00:57:57] Like, that's insane to think about[00:57:59] Yeah. Oh, well we won't speculating You can run in Inside Chat runs Python. Oh, really? Is that, is that happening? I mean, it has a file system and it has file storage and CPU at memory. Yeah.[00:58:20] is turtles all the way down. Turtles all the way down, man.[00:58:23] The, I, I think the plugin system, if people can get to run their own models like the LAMA ones and the same structure for plugins, you can see like going back to the Metaverse thing like a and snow crash where people built their own like demons. You know, it's like I got the demonn that like kicks people out of the club, the, the black sun.[00:58:43] But you can see in real life it's like I have a bunch of plugins that only I have, you know, and I use them to make myself more productive, use them to make myself, you know, look like I'm working when I'm not working and I'm like responding to my emails and stuff like that. But I think like, The OpenAI releasing this today makes it so much easier to start it because you don't have to worry about any of the infrastructure.[00:59:07] You just build the plugin and then they run everything and you get the best model possible. But I think none line, you know, I would love to walk around with my own, you know, raspberry pie or whatever of my wrist, kind of like I'm fall out and say, Hey, I wanna do this, I wanna do that. I don't know, I don't think we're that far away, so I'm excited to, to keep building.[00:59:28] Shoot, the, the technology exists where you could make that now, but it'd be a little awkward to have

The Purple Reign Podcast
Season 8 Episode 2 - On a 'QUANTON' level

The Purple Reign Podcast

Play Episode Listen Later Mar 6, 2023 77:17


After a week on the track, the PR boys are a little better for the run and working on a 'quanton' level to improve each episode. This week we break down practice match 2 with the GBD, Peel Talk, Listener's Questions and a new segment Oz's Macho Man of the Week. Don't forget to listen, rate, review and subscribe to the Purple Reign Podcast. Our merch can be found by clicking the following link: Purple Reign merchandiseSee omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Fremantle 2022 Season review

The Purple Reign Podcast

Play Episode Listen Later Sep 22, 2022 90:56


2022 was a heck of a ride! We went from outside the eight in 2021 to sniffing at a Prelim in 2022. In this episode, we recap the Dockers season through the GBD, Oz's Rankings, look at Peel's loss to the Tigers, Trade news and Listeners' questions. Don't forget, for adult Reign listeners, you can take advantage of Liqourland's podcast unique code by clicking here. Check out our latest clothing and merch line by clicking here.See omnystudio.com/listener for privacy information.

The Purple Reign Podcast
Fremantle vs Western Bulldogs

The Purple Reign Podcast

Play Episode Listen Later Sep 5, 2022 79:12


Never in doubt? Never in a million years? Never have I seen it? Never have I ever? In a tale of almost two halves, Fremantle clawed their way back from the end of the road to get back on the bus! In this episode, we break down what was an epic final's clash. Look at a slightly different take on the GBD, get around the Listener's Questions, and look forward to Saturday night at the G! Don't forget for the adult Reign listeners, you can take advantage of Liqourland's podcast unique code by clicking here. Check out our latest line by clicking here for those wishing to rep new merch.See omnystudio.com/listener for privacy information.

Go Beyond Disruption
GBD174. All about our new show

Go Beyond Disruption

Play Episode Listen Later Aug 18, 2022 13:04


We're transforming! In September 2022, the GBD podcast will become 'FLP, the Finance Leadership podcast'.  Kyle Hannan and AICPA & CIMA colleague Kevin Gormley share an update on what we've been up to and what you can expect from the new show. About Our Podcast. These conversations with expert guests are recorded by different AICPA & CIMA team members from our offices around the world. While the sound quality may vary, we hope that the insights will be consistently useful. Contact us. Get in touch at podcast@aicpa-cima.com ©2018-2022 Association of International Certified Professional Accountants (AICPA & CIMA)

Guys Being Doods
This Last Weekend〡Guys Being Doods Podcast

Guys Being Doods

Play Episode Listen Later May 18, 2022 25:49


On today's episode, the dudes start off mentioning how the NBA continues to excite as we are now down to the FINAL FOUR in the 2022 NBA playoffs. Hear as we breakdown each team and give our predictions... The NBA Conference Finals are an exciting time, and for the 2nd time in 3 years, the Boston Celtics and Miami Heat will compete for a spot in the NBA Finals! In the West, the Mavericks knocked off a solid Phoenix Suns team to take on the Warriors in the Western Conference Finals. Who will take home the gold? Moving on, the dudes talk about their weekends. Luke went to two baseball games, getting to see the Angles vs A's and Phillies vs Dodgers, and RJ was busy getting after it at Washington Union. RJ also got to experience the latest and greatest new alcoholic beverage, "Happy Dad." Find out how he felt about it here only on Episode 48! 

Sustainable Dish Podcast
Frédéric Leroy, PhD on The Global Burden of Disease

Sustainable Dish Podcast

Play Episode Listen Later Apr 19, 2022 54:36


Frédéric Leroy, PhD is back on the podcast to give us an update on the Global Burden of Disease controversy. As many listeners know, he and his team wrote a letter to the GBD authors requesting evidence to show the justification for the 36-fold increase in deaths attributed to meat consumption. After months of fruitless effort to get their letter published, a response was finally received. Frédéric and I discuss the recent problematic trend in mainstream media of refusing to present dialogue that counters popular “science” in order to promote the anti-meat narrative.  Episode resources and transcripts are available at www.sustainabledish.com Episode Credits: Thank you to all who've made this show possible. Our hosts are Diana Rodgers and James Connelly. Our producer is Emily Soape. And of course, we are grateful for our sponsors, Patreon supporters, and listeners. Thank you to Dry Farm Wines for their continued support of my work. Their wines are all-natural and low in alcohol which means less of a foggy feeling the next day. They have a great selection of sparkling, whites, rosés, and reds. And when you visit sustainabledish.com/wine you can check out their latest special offer exclusively for listeners of the Sustainable Dish podcast.

The Paradocs Podcast with Eric Larson
The Way to Build False Scientific Consensus with Dr. Jay Bhattacharya

The Paradocs Podcast with Eric Larson

Play Episode Listen Later Apr 14, 2022 55:54


Dr. Jay Bhattacharya returns today to further our discussion on the dysfunction within the scientific community around COVID-19. Specifically, we discuss what exactly happened to Dr. Bhattacharya after he co-authored the Great Barrington Declaration where he and two other prominent academicians laid out a case for a more focused protection plan for the elderly than the widely adopted general lockdowns and mandates at the time. Dr. Bhattacharya was not surprised to face opposition to their plan - but the way it formed and by whom did.  A Government Bureaucratic Cabal?After the publishing of the GBD, the attack against Dr. Bhattacharya and his co-authors was blistering, numerous, and seemingly coordinated. Those on the outside, and even Dr. Bhattacharya himself, believed that the scorn from media, government, and academia was due to a general disagreement with their position - not a coordinated attack. It turns out that FOIA documents of emails from Drs. Fauci (head of NIAID) and Collins (head of NIH) prove that they worked in tandem to discredit the GBD through their contacts within the scientific, media, and government communities. Learn more about your ad choices. Visit megaphone.fm/adchoices

Trish Wood is Critical
Jay Bhattacharya On An Important COVID Apology

Trish Wood is Critical

Play Episode Listen Later Mar 12, 2022 116:24


This week an important event in COVID-history exploded when a doctor apologized and admitted to the Great Barrington / focused protection signatories he'd been completely wrong in thinking about the pandemic. It was a lovely moment for Dr. Jay Bhattacharya, after nearly two years of abuse and smears that made him an outcast in some circles. The GBD plan is becoming widely accepted now that research is showing lockdowns did more harm than good.