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Cannabis, Kaneh Bosm, and the Quest to Heal the World by 2025In this episode of the Miracle Plant Podcast, I delve into the incredible healing properties of cannabis, also known as Kaneh Bosm, and its historical significance. I share a personal anecdote about how our Miracle Plant Roll-On provided immediate relief for my toe pain, emphasizing the plant's efficacy without side effects or drug interactions.We kick off 2025 with our ongoing mission to reach a billion people by the end of the year, spreading awareness about the transformative power of this miracle plant. I discuss our recent launch of the Kaneh Bosm Connection, linking the ancient use of Kaneh Bosm in the Holy Anointing Oil to modern-day cannabis. This connection is rooted in historical texts, including the Old Testament and the Dead Sea Scrolls, which highlight the plant's use for healing by high priests and even Jesus Christ.I emphasize the importance of going viral to achieve our mission, whether through social media, podcasts, or influential platforms. I also touch on the potential impact of educating religious leaders, like the Pope, about the true nature of cannabossum. This could shift the global perception of cannabis, especially among the 2 billion Catholics worldwide.Throughout the episode, I critique the pharmaceutical industry and advocate for a return to plant-based medicine. I highlight the dangers of synthetic drugs and the benefits of natural remedies like cannabis. I also discuss the historical mistranslation of cannabossum in biblical texts and its implications for modern medicine.Finally, I encourage listeners to do their own research, engage in conversations, and explore the benefits of this miracle plant. Our goal is to change the way people think about cannabis, from a stigmatized drug to a powerful, natural healer. As always, we end the episode with our mission statement: "Heal the world," aiming to inspire and educate as many people as possible about the healing potential of cannabis. Happy 2025, and let's continue this journey together!ASK ANYTHING ABOUT THIS EPISODETIMESTAMP00:00:00 - Introduction and Personal Testimony00:00:43 - Welcome to the Miracle Plant Podcast00:01:14 - Mission to Reach a Billion People by 202500:02:05 - Kaneh Bosm Connection and Historical Context00:03:00 - Kaneh Bosm in the Old Testament00:04:05 - Google Search and Online Presence00:05:05 - Biblical Scholars and the Pope00:06:01 - Jesus and the Holy Anointing Oil00:07:05 - The Chosen TV Show Reference00:08:07 - Historical Use of Cannabossum00:09:03 - Potential Impact of Pope's Endorsement00:10:09 - Chris Bennett's Research00:11:02 - Big Pharma and FDA Critique00:12:07 - Plant-Based Medicine vs. Pharmaceuticals00:13:08 - Personal Anecdote on Miracle Plant Roll-On00:14:01 - Autism and Personal Covenant with God00:15:05 - Encouragement to Do Research00:16:09 - Dr. Ethan Russo and Endocannabinoid System00:17:04 - Dead Sea Scrolls and Historical Accuracy00:18:07 - Importance of Holy Anointing Oil00:19:01 - Personal Testimony on Pain Relief00:20:06 - Mission to Educate About Miracle Plant00:21:10 - Chris Tucker Movie Reference00:22:02 - YouTube and Social Media Strategy00:23:07 - Historical Use of Hemp and Cannabinoids00:24:00 - Modern Challenges and Toxicity00:25:04 - Hope for Change in 202500:26:06 - Call for Safe Consumption and Transparency00:27:01 - Raising Consciousness Through Plant-Based Medicine00:28:04 - Benefits of the Miracle Plant00:29:08 - Closing Remarks and Call to Action Thank you for tuning in to the Miracle Plant Podcast. Remember, our mission is to heal the world with the power of this miracle plant. Join us next time for more inspiring stories and insights into the world of cannabis. Produced by PodConx 101cbd - https://101cbd.org/Email Justin Benton - jbenton@101cbd.orgGet a free consultation - askjanet.orgKaneh Bosm Connection - https://youtube.com/@kanehbosmconnection
Dr. Ethan Russo has made immense contributions to the understanding of cannabis. 2024 was particularly productive as Dr. Russo's name kept popping up in some very interesting papers. We got him to chat with us about two of them.First there is the entourage effect paper. The entourage effect is the idea that different cannabinoids, terpenes and other components of the cannabis plant work together synergistically to give a desired effect. Professor Raphael Mechoulam and colleagues first talked about the entourage effect amongst endogenous cannabinoids in the human body. Dr. Ethan Russo and others have expanded the idea to phytocannabinoids and other cannabis plant components. But it is still just an idea. Now there is a trial that looks at if inhaled limonene makes THC cause less anxiety in people. This could be the beginning of the evidence to validate the entourage effect.Second, we chatted about a CBG paper. We have a lovely sound bite that describes CBG as a “bubble bath for your brain”. This study gives us some early evidence of the clinical effects of CBG, and whether it actually reduces anxiety.Let's do some learning!Ethan Russo.org - WebsiteEthan Russo- LinkedInCReDO Science - WebsiteVaporized D-limonene selectively mitigates the acute anxiogenic effects of Δ9-tetrahydrocannabinol in healthy adults who intermittently use cannabis. - PaperAcute effects of cannabigerol on anxiety, stress, and mood: a double‑blind, placebo‑controlled, crossover, field trial. - PaperMusic by:Dark Star by The Grateful Dead - YouTube(Yes we got a SOCAN membership to use this song all legal and proper like)Additional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca
Dr Ethan Russo has been involved in cannabis research for many years. He dispels some of the myths and talks about recent breakthroughs in the treatment of anxiety and dementia. Dr Russo focuses on current research into limonene and cannabigerol. A fascinating conversation with a true expert. Links: Ethan's site: https://ethanrusso.org Acute effects of cannabigerol on anxiety, stress, and mood https://ethanrusso.org/acute-effects-of-cannabigerol-on-anxiety-stress-and-mood-a-double%E2%80%91blind-placebo%E2%80%91controlled-crossover-field-trial/ Vaporized D-limonene selectively mitigates the acute anxiogenic effects of Δ9-tetrahydrocannabinol in healthy adults who intermittently use cannabis https://ethanrusso.org/vaporized-d-limonene-selectively-mitigates-the-acute-anxiogenic-effects-of-δ9-tetrahydrocannabinol-in-healthy-adults-who-intermittently-use-cannabis/ PISA tables https://www.oecd.org/en/about/programmes/pisa.html
Kirk and Trevor discuss PTSD with Dr. Mike Hart founder of ReadyToGo Clinic. Dr. Hart talks about how PTSD, migraines, IBS and some other conditions are due at least in part to an endocannabinoid deficiency. That means cannabis is an obvious treatment for PTSD. Also hear how cannabis can also be used in sports medicine and about Kirk's Runners' High on the Columbia Ice Fields.Dr. Mike Hart's Joe Rogan Interview (Episode 1246) - YouTubeScientific American “The Case of a Woman Who Feels Almost No Pain Leads Scientists to a New Gene Mutation” - March 30/19 - Jacquelyn Corley - ArticleReadytogo Clinic - WebsiteMike Hart Book - Friendly Fire: Why Vets Are Ditching Pills and Lighting Up to Treat PTSD - AmazonBenzodiazepines for PTSD: A Systemic Review and Meta-Analysis. Guina et al. Journal of Psychiatric Practice. July 2015- ArticleReductions in Circulating Endocannabinoid Levels in Individuals with Post-Traumatic Stress Disorder Following Exposure to the World Trade Center Attacks. Matthew N. Hill et al. Psychoneuroendocrinology. Sept 2013. - ArticleClinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes. Ethan Russo. Cannabis and Cannabinoid Research. July 2016. - ArticleMusic by:Bif Naked - Santa Claus is Coming to Town -YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca
How Consumption Methods Affect Cannabis Chemistry | Dr. Riley Kirk | Bioactive Podcast In this episode of the Bioactive Podcast, Dr. Riley Kirk breaks down how cannabis consumption methods—whether smoking, vaping, or edibles—can impact the chemistry and effects you experience. We often focus on strain-specific effects to curate our cannabis experience, but your method of consumption also plays a key role. Different methods produce unique combinations of compounds, changing how you experience the Entourage Effect. This theory, introduced by Dr. Ethan Russo, explains how the many compounds in cannabis work together synergistically—often making the whole experience greater than the sum of its parts. But did you know the entourage effect varies with each consumption method? Dr. Riley Kirk shares her personal insights into how smoking, vaping, and edibles produce different results. Learn how to tailor your cannabis experience by understanding the relationship between strains and consumption methods. Subscribe to the Bioactive Podcast for more insights into cannabis science and chemistry, and join our Patreon community for early access to episodes and bonus content. Visit www.Patreon.com/cannabichem or contact Riley at BioactivePodcast.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
Join us for another great episode of Hash Church Early on we have Dr Ethan Russo talking about CbG and its incredible effects on anxiety when used with particular terpenes. We also have Michael Krawitz who shares some of what he has been doing in politics with cannabis legalization around the world, and how they are working hard on reducing the execution of cannabis prisoners world wide. He also shares some of his awesome historical cannabis collection. We also have Chris Gassa from Harvard University and his colleague and my friend Davis Allen. we get into a great land race conversation which really goes deep with Mojave Richmond, Ryan Lee aka Chimera and Skunkman Sam. We also have a wonderful conversation on the volatile organic compounds of cannabis. Thanks to Dr Mark Scialdone for taking us nice and deep down that rabbit hole. Then we get into the plant breeders rights applications with Ryan Lee and skunkman sam . Finally we end it with Bryon from Best friend farms and a discussion on septoria and Blight. what an amazing episodeSupport the show
Dr. Ethan Russo is a neurologist and psychopharmacology researcher, who in the medical community, is a self-described “salmon upstream against the current.” After a transformative experience with natural medicine in the Peruvian rainforest, the pharmacologist now spearheads cannabis and psychedelic research in an effort to treat the untreatable. Get early access to ad-free episodes, bonus content, and more by supporting Labyrinths on patreon. https://www.patreon.com/knoxrobinson https://www.amandaknox.com Twitter: @amandaknox | @manunderbridge IG: @amamaknox | @emceecarbon Learn more about your ad choices. Visit megaphone.fm/adchoices
In groundbreaking new science, for the first time we have a human study showing that 78% of participants found cannabigerol (CBG) more effective at treating their anxiety than their present pharmaceutical, herbal remedy or other therapeutic. During this episode of Shaping Fire, host Shango Los welcomes back Dr. Ethan Russo to discuss the foundations of the study, the mechanics of causing and measuring anxiety in the participants, efficacious CBG dosages, and the remarkable findings that may change the direction of anxiety medication development going forward.
Weed has gone mainstream, and it's been rebranded as a wellness drug that you can customize to fit your needs. Want to feel relaxed? Well, you'll need a kind of pot called Indica. Want to get pepped up? Go for Sativa. But what can weed really do for us? We're going to pack a bowl full of science facts, sit back, put our feet up and find out: Can cannabis really improve your mental health? Does it matter what strain you take? And how safe is it – can it mess with your memory? To find out, we talk to agricultural scientist Dr. Sean Myles, neuroscientist Dr. Amir Englund, and psychologist Dr. Carrie Cuttler. Find our transcript here: https://bit.ly/ScienceVsCannabisTranscript In this episode, we cover: (00:00) A New World of Weed (05:32) Can Different Strains of Weed Do Different Things for You? (13:18) Can CBD Give You a More Mellow High? (22:46) Can Weed Help with Anxiety or Depression? (24:55) What Are The Risks of Using Cannabis? (35:30) What's the Safest Way to Use Cannabis? (38:25) Can Weed Boost Your Creativity? This episode was produced by Meryl Horn, with help from Wendy Zukerman, Rose Rimler, Michelle Dang, and Joel Werner. We're edited by Blythe Terrell. Fact checking by Eva Dasher. Mix and sound design by Bobby Lord. Music written by Bobby Lord, Bumi Hidaka and Peter Leonard. Thanks to all the researchers we spoke to including Professor Ryan Vandrey, Professor Christopher Barnes, Dr. Siqi Xue, Professor Susan Tapert, Dr. Michael Dunn, Dr. Linda Parker, Professor Deepak D'Souza, Professor Vikaas Sohal, Professor Loren Frank, and Dr. Ethan Russo. Also thanks to Jill Conforti, the Zukerman Family, Joseph Lavelle Wilson, Bernadette Sciandra, and Chris Suter. Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Dr. Ethan Russo is a board-certified neurologist, psychopharmacologist, and Founder/CEO of CReDO Science. He is an internationally recognized authority on cannabis medicine. He has authored/edited seven books and has published more than 60 peer-reviewed articles. He also holds director/advisor positions with several cannabis therapeutics companies, and he was instrumental in developing Sativex® for pain and MS, and Epidiolex® for intractable epilepsy while at GW Pharmaceuticals. At CannMed 24, Ethan will present “Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot”. CHS is an enigmatic condition where some chronic, heavy users of THC develop a cyclic pattern of vomiting and nausea that is only relieved by hot bathing and topical capsaicin. Ethan and his coinvestigators surveyed more than 500 cannabis users, including 205 diagnosed CHS patients, and investigated genetic mutations in 28 CHS patients and 12 controls to identify behaviors and genetic markers that could indicate CHS risk. During our conversation, we discuss: What is CHS and who does it affect Why cases of CHS appear to be on the rise Possible genetic markers that could indicate CHS susceptibility Steps cannabis users can take to prevent developing CHS Why some people in the cannabis community don't believe CHS is a real thing and more Thanks to This Episode's Sponsor: Cannabis Nurses Network Established in 2015, the Cannabis Nurses Network™ is a professional nursing and professional development organization for nurses around the globe. By educating nurses on the science behind the plant and providing a global nursing network, nurses are supported and empowered to implement their knowledge within their community. Learn more at cannabisnursesnetwork.com Additional Resources what-is-chs.com ethanrusso.org CReDO-science.com Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation Unraveling the Mystery of Cannabinoid Hyperemesis Syndrome - CannMed 2019 Panel Register for CannMed 24 What Makes CannMed Unique and Why You Don't Want to Miss It Review the Podcast! CannMed Archive
In this episode of the Smarter Not Harder Podcast, host Jodi Duval is joined by guest Ethan Russo to give one-cent solutions to life's $64,000 questions that include: What is the endocannabinoid system's role in human health and how does it have potential in treating conditions like migraines, fibromyalgia, and irritable bowel syndrome? What is the medicinal potential of lesser-known cannabinoids like CBG and THCV in treating anxiety, specific cancers, and MRSA infections? How do lifestyle factors like diet and exercise influence the endocannabinoid system and how can an anti-inflammatory diet and aerobic activity boost endocannabinoid levels? Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and author. He is the Founder and CEO of credo-science.com. What We Discuss: (0:02:04) - Dr. Ethan Russo's journey into the world of cannabis and medicinal plants, his transformative experience with the Machiguenga tribe in the Amazon, and his work on the endocannabinoid system and clinical endocannabinoid deficiency (0:20:55) - The potential of cannabigerol (CBG) and other cannabinoids like THCV and CBDV, the concept of the 'entourage effect', and the therapeutic promise of acid cannabinoids such as THCA (0:33:40) - The efficacy of cannabis-based medicines, the science behind cannabinoid and terpenoid formulations, insights from Dr. Russo's work at Carito Science, the challenges faced by the cannabis industry, and the importance of natural, soil-based growth and sustainable agriculture. (0:47:47) - The current landscape and future potential of cannabis research, its promise in treating various health conditions, and advice on optimizing the endocannabinoid system through diet and activity (0:55:55) - The relationship between music and the endocannabinoid system, including the idea that singing can elevate endocannabinoid levels and contribute to improved mood and alertness Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram. Find more from Dr. Ethan Russo: Websites: https://credo-science.com/ | https://ethanrusso.org/category/library/ | https://andira.ca/ | https://www.canurta.com/ LinkedIn: https://www.linkedin.com/company/credo-science/ YouTube: https://www.youtube.com/@dr.ethanrusso
A short intro for the eminent Dr. Ethan Russo is challenging. Ethan Russo is a neurologist who explored the Amazon rain forest in the 90's to explore medicinal plants with aboriginal tribes. He returned to the USA and became interested in medicinal cannabis. He quickly became an expert in the field, and worked as a consultant for GW Pharmaceuticals. Later, as a Senior Medical Advisor for GW, he was involved with the development of Sativex and Epidiolex.Dr. Russo founded CReDO Science, who create innovative products and services related to cannabis and the endocannabinoid system. Trevor and Dr. Russo discuss Cannabinoid Hyperemesis Syndrome (CHS). It is a relatively rare, but very unpleasant condition that causes some heavy users of cannabis to be very nauseous and vomit a lot. Dr. Russo and collaborators have developed a genetic test that may be able to predict who will get CHS and thus who might want to avoid THC containing cannabis altogether.Then Trevor and Dr. Russo discuss THCV. Come hear about all the potential indications for this lesser known cannabinoid.Make sure you listen to the very, very end of this episode for a hidden my cannabis story.Ethan Russo Website - ethanrusso.orgCannabinoid Hyperemesis Syndrome Survey and Genomic Investigation - articleCHS DNA test - what-is-chs.comMusic by: Nelson Little - High Road - YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca
In this episode of the Smarter Not Harder Podcast, host Boomer Anderson is joined by guest Jodi Duval to give one-cent solutions to life's $64,000 questions that include: What is the history and role of various components of cannabis, including THC, CBD, and other cannabinoids, in medicine, and how does their research into the impact on the endocannabinoid system pave the way for further exploration in the field? What is the 'Entourage Effect' and how does the combined effect of different cannabinoids and terpenes found in cannabis, particularly their anti-inflammatory, anti-depressant, neuro-protective, and sedative effects, indicate the vast potential of cannabis in healthcare? Why is understanding and measuring endocannabinoid tone, which can impact pain threshold, digestion, mood, and sleep, important and how can genetic testing, symptomatology, and tracking be used to assess it? What is the significance of working with a knowledgeable practitioner with medicinal cannabis? What We Discuss: (0:01:03) - Exploring the history and various components of cannabis as a medicine (0:07:12) - The origins of cannabis use for medicine in Tibet and the potential of cannabis components for various effects (0:10:24) - The endocannabinoid system, the differences between CB1 and CB2 receptors, and their impact on human health (0:22:50) - The clinical relevance of the 'Entourage Effect' and the importance of combining cannabinoids for maximum efficacy (0:34:40) - The insights into the challenges of sourcing quality cannabis and the importance of working with a practitioner Find more from Jodi Duval: Clinic: https://www.instagram.com/revital_health/ Instagram: https://www.instagram.com/jodi.duval/ Cannabis Module: https://homehope.org/products/cannabis Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram. Resources: Book: Hope & Healing, The Case for Cannabis by Dr. Joseph Rosado EndoDNA: https://endodna.com/ Ethan Russo: https://ethanrusso.org/ The Cannabis Conversation | Medical Cannabis | CBD | Hemp Podcast Cannabis Chemovars Zhu H, Wang J, Zhang Z, et al. Cannabihumanindoles from Cannabis with a structural resemblance to human indoles. Nature. 2022 Feb;602(7897):470-475. doi: 10.1038/s41586-021-04387-1. Epub 2022 Jan 26. Endocannabinoid Deficiency and Migraine (2022) HOMe/HOPe Cannabis Course
In this episode, we have the privilege of chatting with Dr. Ethan Russo, a renowned neurologist, and cannabis researcher. Dr. Russo's pioneering work in the field has significantly contributed to our understanding of cannabinoids, terpenes, and their intricate interactions within the human body. It was huge pleasure to chat with him for an hour or so and I hope we can get him back on th show in the future to chat more. It was truly a pleasure to chat with him. So roll yourself a couple of fat ones, and get ready for an awesome interview with Dr Ethan Russo! If you have any suggestions for guest to be on our cannabis podcast then please feel free to contact us on our website, Discord server, or any of your favourite social networks. Visit our website for links. Website: https://highonhomegrown.com Discord: https://discord.gg/sqYGkF4xyQ Youtube: https://www.youtube.com/highonhomegrown Thank you for downloading and listening to our cannabis podcast!
Delta-8 THC is everywhere, but the scientific understanding of it is not. On this episode of Shaping Fire, host Shango Los welcomes back neuroscientist and renown cannabis researcher Dr. Ethan Russo to discuss the medicinal benefits of Delta-8 THC, its history, the challenges of synthesizing clean Delta-8 THC, and the negative impacts that synthetic Delta-8 THC is having throughout the cannabis community.
A short intro for the eminent Dr. Ethan Russo is challenging. Ethan Russo is a neurologist who explored the Amazon rain forest in the 90's to explore medicinal plants with aboriginal tribes. He returned to the USA and became interested in medicinal cannabis. He quickly became an expert in the field, and worked as a consultant for GW Pharmaceuticals. Later, as a Senior Medical Advisor for GW, he was involved with the development of Sativex and Epidiolex.Dr. Russo founded CReDO Science, who create innovative products and services related to cannabis and the endocannabinoid system. Trevor and Dr. Russo discuss Cannabinoid Hyperemesis Syndrome (CHS). It is a relatively rare, but very unpleasant condition that causes some heavy users of cannabis to be very nauseous and vomit a lot. Dr. Russo and collaborators have developed a genetic test that may be able to predict who will get CHS and thus who might want to avoid THC containing cannabis altogether.Then Trevor and Dr. Russo discuss THCV. Come hear about all the potential indications for this lesser known cannabinoid.Make sure you listen to the very, very end of this episode for a hidden my cannabis story.Ethan Russo Website - ethanrusso.orgCannabinoid Hyperemesis Syndrome Survey and Genomic Investigation - articleCHS DNA test - what-is-chs.comMusic by: Nelson Little - High Road - YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca
Join myself, Dr Ethan Russo, Dr Mark Scialdone, Robert Connel Clarke and SkunkMan sam remember a great Chemist in cannabis. Raphael MechoulamSupport the show
Starting in the 1960s, a single cannabis research group discovered THC, CBD, CBG, CBC, CBNa, CBDa, CBGa and others! On this episode of Shaping Fire, host Shango Los talks with Dr. Ethan Russo about the life's work of Dr. Raphael Mechoulam, who passed away last week. Dr. Russo shares engaging stories from Dr. Mechoulam's life, walks us through the historical timeline of his discoveries, and explains the momentous impact of the greatest cannabis researcher we've ever known.
You are still living in a vicious world where balance has yet to be found. And that is never more obvious when listening to Penny Daugherty, RN, living in Atlanta, GA in 2023, trying to help patients deeply involved in Western Sick Care who feel death closing in. But help is available. You can find Penny on LinkedIn but she says “You can reach me on any app… I'm just here for the party!” And that party begins when you start feeling better because of her help. Dr. Nasha Winters: https://www.drnasha.com/ The Doctors Knox: https://doctorsknox.com/ Ashley Manta: https://www.ashleymanta.com/ Dr. Genester Wilson-King: https://victoryrejuvenationcenter.com/ The Dog Lived: https://a.co/d/cf9lx3r Katherine Eban (https://www.katherineeban.com/bottleoflies) Dr. Ethan Russo: ethanrusso.org and trueterpenes.com The Doctors Knox: https://doctorsknox.com/ --- Send in a voice message: https://podcasters.spotify.com/pod/show/cannabaverum/message Support this podcast: https://podcasters.spotify.com/pod/show/cannabaverum/support
In this week's podcast we chat with Dr Ethan Russo MD, Doctor & Researcher, about:Cannabis - The Entourage EffectCannabis synergiesCannabis formulationsPlant derived cannabis vs. synthetic cannabinoidsGenetic predispositions to cannabinoid hyperemesis syndromeCryo-kief - Preserving cannabinoids through novel manufacturing practicesDr Ethan Russo MD:https://ethanrusso.org/AltMed:https://altmed.com.au/
What's wrong with the cannabis industry?Joining us again on the latest episode of The Cannabis Conversation is Dr Ethan Russo, Founder of Credo Science - a novel medical science company.We discuss the prejudice and ignorance against Cannabis, as well as safety monitoring, legalisation and some of the challenges the industry is facing, including a lack of proper funded research in the area.The Cannabis Conversation is sponsored by Lumino - a boutique HR and Recruitment Agency specialising in building high performance teams for the European Cannabis Industry. They work in three main verticals: Commercial, Medical and Plant Facing.Get in touch at www.luminorecruit.com/About Ethan RussoEthan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and Founder/CEO of CReDO Science https://credo-science.com He is also Medical Director of Andira Pharmaceuticals Andira – Bringing Healing to Life and Senior Medical Advisor to Canurta Home | CanurtaPreviously he was Director of Research and Development for the International Cannabis and Cannabinoids Institute, 2017-19, Medical Director of PHYTECS, 2015-2017, and from 2003-2014, Senior Medical Advisor, medical monitor/study physician to GW Pharmaceuticals for numerous Phase I-III clinical trials of Sativex® and Epidiolex®.He was a clinical neurologist in Missoula, Montana for 20 years. He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, and in Medicine at the University of Washington. He is author/editor of seven books and has published more than 50 peer-reviewed articles.ResourcesJoin Dr. Russo on LinkedIn: https://www.linkedin.com/in/ethan-russo-md-468b19a/View Dr. Russo's clinical research papers: https://www.researchgate.net/profile/Ethan_RussoCReDO Science Website: https://credo-science.com/
Dr. Ethan Russo and Nishi Whiteley have worked together for almost 10 years in efforts to:improve the scientific understanding of the endocannabinoid system (ECS) and how the cannabis plant modulates itassist small and large cannabis companies in product formulationadvise companies on cannabis genetics enhancementsconsult on pre-clinical and clinical research design.“We share a vision of making cannabis better and safer believing in a future in which knowledge of the endocannabinoid system and its therapeutic modulation via the cannabis plant will result in superior highly individualized medicines, aids to wellness, enhanced lifestyles, and novel non-toxic industrial products”.Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and author. He is the Founder and CEO of CannabisResearch.org. Previously, he was Director of Research and Development at the International Cannabis and Cannabinoids Institute (ICCI) based in Prague, Czech Republic. Medical Director of PHYTECS (2015-2017), a biotechnology company researching and developing innovative approaches targeting the human endocannabinoid system, and from 2003-2014, he served as Senior Medical Advisor, medical monitor, and study physician to GW Pharmaceuticals, United Kingdom for numerous Phase I-III clinical trials of Sativex® for alleviation of cancer pain unresponsive to optimized opioid treatment and initial studies of Epidiolex® for intractable epilepsy.Nishi Whiteley (pronounced Nee-sha), is the co-founder and Chief Operating Officer at CReDO. She has twenty-five-plus years of international business development experience in cannabis, agriculture, wellness, green energy, and food industries. She has had leadership roles on projects in corporate America and for the US Foreign Ag Service in over 10 countries, in startups, a state agency, and non-profits; as well as worked for foreign governments and met with international leaders in Cuba, Mexico, and the Dominican Republic to open trade and advance development programs. She has worked on investment projects in 8 countries.
LJ Amaral is a Clinical and Research Dietitian specializing in Oncology at Cedars-Sinai Hospital in Los Angeles. She is currently doing research on the ketogenic diet as an adjunct treatment to the standard of care for brain cancer patients. Find LJ at https://www.ljamaral.com Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and former Senior Medical Advisor to GW Pharmaceuticals. He served as study physician to GW Pharmaceuticals for three Phase III clinical trials of Sativex. He is author of Handbook of Psychotropic Herbs, co-editor of Cannabis and Cannabinoids: Pharmacology, Toxicology and Therapeutic Potential, and author of The Last Sorcerer: Echoes of the Rainforest. He was founding editor of Journal of Cannabis Therapeutics, selections of which were published as books: Cannabis Therapeutics in HIV/AIDS, Women and Cannabis: Medicine, Science and Sociology, Cannabis: From Pariah to Prescription, and Handbook of Cannabis Therapeutics: From Bench to Bedside. He has also published numerous book chapters, and over thirty articles in neurology, pain management, cannabis, and ethnobotany. - - - In this live salon from 9/20/22 on Clubhouse, Ethan, Dr. Russo and LJ discuss the current research and opportunities presented for brain cancer patients when it comes to diet and nutrition, specifically the Ketogenic Diet and the use of cannabis to treat brain cancer. This conversation was hosted with the support of xCures, learn more and signup for their xINFORM platform that pairs patients with clinical trials at www.xcures.com/brain Learn more about LIFECHANGES at www.ourlifechanges.co and the Love Extremist Project at www.extremist.love
Today's episode will be slightly different to the norm… Having received a few notes from newer listeners keen to understand more about individual cannabinoids, I thought it would be cool this week to play out a session that ran last year at the GCI Summit with none other than Dr. Ethan Russo. As one of the modern-day OGs of cannabis research and science, it is always a pleasure to pick the brain of Ethan, who is an unequivocal authority on the plant and its constituent parts. As a heads up, the session was initially recorded on Zoom, so the audio quality will be slightly different to the typical pods; however, I hope that hearing the wonderful insights of Dr. Russo will be enough of an audio feast for you!Take a look at the full collection of podcasts and explore additional cannabis & psychedelics content on the GCI Content Hub: https://contenthub.gcintelligence.com/
Ethan Russo, MD, is known as the godfather of cannabis. He is a board-certified neurologist, psychopharmacology researcher, and author. He is also the Founder and CEO of credo-science.com. Previously, he was Director of Research and Development of the International Cannabis and Cannabinoids Institute (ICCI) based in Prague, Czech Republic. In this podcast, we discuss why Sativa vs. Indica nomenclature needs to be phased out, "the entourage effect," the specific clinical applications of THCV, CBN, CBG, and how to use terpenes to enrich your cannabis experience.
Dr. Russo is a board-certified neurologist, psychopharmacology researcher, and author. He is the Founder and CEO of credo-science.com. He graduated from the University of Pennsylvania (Psychology), and the University of Massachusetts Medical School, before residencies in Pediatrics in Phoenix, Arizona and in Child and Adult Neurology at the University of Washington in Seattle. He was a clinical neurologist in Missoula, Montana for 20 years in a practice with a strong chronic pain component. In 1995, he pursued a 3-month sabbatical doing ethnobotanical research with the Machiguenga people in Parque Nacional del Manu, Peru. He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, in Medicine at the University of Washington, and as visiting professor, Chinese Academy of Sciences, Harvard University, and Johns Hopkins University. He has also published numerous book chapters, and over fifty articles in neurology, pain management, cannabis, and ethnobotany. His research interests have included correlations of historical uses of cannabis to modern pharmacological mechanisms, phytopharmaceutical treatment of migraine and chronic pain, herbal synergy and phytocannabinoid/terpenoid, serotonergic and vanilloid interactions. He has consulted or lectured on these topics in 39 US states and Canadian provinces and 39 countries.
The Terpenes and Testing Podcast with Dr. Jason Lupoi, Editor in Chief
On this episode, Dr. Lupoi chats with the esteemed board-certified neurologist, psychopharmacology researcher, and author Dr. Ethan Russo. Discussion points include the endocannabinoid system (ECS) and our bodies seeming almost mechanized to utilize cannabinoids, whether a medical doctor can properly treat us without knowledge on the ECS, Dr. Russo's travels to South America in search of ethnobotanical plants, and a candid discourse on synthetic cannabinoids like delta-8-THC, THCP, and HHC.
CannMed 2022 is officially in the books. Thank you to all our attendees, presenters, sponsors, exhibitors, media partners, and team members behind the scenes who make it all possible. It was great to see everyone in person again and learn about the latest advancements in the field. We discussed novel cannabinoids, new treatment protocols, exciting new advances in breeding and cultivation, stronger safety testing methods and of course, the latest advances in our understanding and use of medicinal mushrooms. We also had the chance to record interviews with some of our presenters in the CannMed Coffee Talk Lounge that we had set up at the venue. Today's episode will feature three of those conversations. The first is with Science Keynote presenter Ethan Russo, MD. The second is with presenter and medical practicum instructor Eloise Theisen, NP. And last but certainly not least is Medicine Keynote, Medical Practicum Instructor, and CannMed staple Bonni Goldstein, MD. Each conversation is 10-15 minutes long and we talk about the value of in-person meetings, such as CannMed, as well as details about each of their presentations. Thanks to This Episode's Sponsor: Medicine Women Health Medicine Women's team of specialists includes Medical Doctors, Naturopaths, Medical Cannabis Experts, Nutritionists and Alternative Health Practitioners. These integrative teams evaluate health issues and design targeted protocols to promote personal healing. Medicine Women's Protocols have successfully alleviated symptoms of Cancer, Auto-Immune Diseases and Neurological Conditions, as well as providing overall Health Rejuvenation. Learn more at medicinewomenhealth.com. Additional Resources CannMed Coffee Talk Lounge Videos CannMed ArchiveCannMed Community Board [Facebook Group]Healthcare Provider Medical Cannabis Research Study
Nishi Whitely, Ethan Russo, and Mojave Richmond from Breeder's Best. They work with breeders to license their patented cultivars in markets worldwide. See omnystudio.com/listener for privacy information.
In the latest episode, we have a special guest Derek of True Terpenes. We met True Terpenes back at MJ Biz Con 2021 and are excited to be able to learn more about Terpenes. We focus heavily on terpenes because we believe that the terps, cannabinoids, flavonoids, and more all play a major role in enjoying cannabis. It's not just the Indica vs Sativa debate.True TerpenesThey are available all over the world you can purchase these terpenes. We discuss what type of terpenes they have from certain strains, live resin terps and more. Make sure you check out trueterpenes.comDr. Ethan Russo is on the staff of True Terpenes and if you have ever looked up inf0ormation on terps you know this Dr. is in almost all of the studies and putting more information out there for people to understand the effects. Did you know each terpene can affect each person differently? Or certain terps are good for daytime compared to nighttime. Terpenes are part of everyday life from the lemon limonene, or peppery caryophyllene you will understand that terps are around us in cannabis and in our seasonings or fruits we eat.It's great to learn about Terpenes from Derek who is very well knowledgeable in this field giving us more insight into terps. We believe terpenes are going to be a major part of the cannabis industry moving forward.Please follow & subscribeJoin us Live Terp Talk Tuesday: 7:10 EST Wake N Bake Saturday 9 Am EST.MiCannaCasthttps://www.micannacast.comhttps://www.facebook.com/Micannacast/https://www.instagram.com/micannacast/https://www.patreon.com/micannacast/https://twitter.com/micannacastCannaDavehttps://www.cannadave.com/https://www.facebook.com/Cannadave420/https://www.instagram.com/cannadave/Grooveehttps://www.facebook.com/GrooveeMusic/https://www.instagram.com/grooveemusic/
Dr. Ethan Russo returns to the podcast to help us make sense of the slew of studies and articles claiming cannabis can treat and/or prevent COVID-19 infection. Dr. Russo is a board-certified neurologist, a psychopharmacology researcher, an author, a lecturer, and a consultant. He is a CannMed 2022 Keynote Presenter, where he will present on Cannabis and Psychiatry. Although Dr. Russo is not a virologist, he is a very accomplished medical cannabis researcher, and he is well-qualified to help us find the signal in all the noise. During the conversation, we discuss: What role the endocannabinoid system plays in preventing and clearing a viral infection The different levels of clinical research The importance of peer review process The University of Chicago study that claims CBD inhibits SARS-CoV-2 replication The Oregon University Study that claims cannabinoid acids can prevent covid infection Animal models showing CBD can calm the cytokine storm A preprint study claiming CBD primes the innate immune system Claims that cannabis smokers have a greater risk for COVID-19 infection Thank You to This Episode's Sponsor: Project CBD Founded in 2010, Project CBD is the first and longest-running website dedicated to research and education on the benefits of CBD, and the premier destination for both curious and committed CBD consumers. Often the first to report on cutting-edge health issues, Project CBD reporting reflects a deeper understanding of developments in cannabinoid science and therapeutics. Learn more at ProjectCBD.com Additional Resources Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responsesCannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging VariantsEvaluation of Serum Cytokines Levels and the Role of Cannabidiol Treatment in Animal Model of AsthmaIn search of preventive strategies: novel high-CBD Cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissuesCannMed ArchiveCannMed Community Board [Facebook Group]Healthcare Provider Medical Cannabis Research Study
No penúltimo episódio da nossa primeira temporada, um tema considerado revolucionário para a medicina moderna. Um assunto que divide opiniões. Mais do que isso, divide conhecimento. O preconceito que envolve o polêmico uso terapêutico da cannabis. De um lado, temos as pessoas que já estudaram, pesquisaram e continuam estudando e pesquisando. São as pessoas que têm o conhecimento. Do outro lado tem quem... sem embasamento nenhum, classifica o canabidiol como se fosse maconha, o que só dificulta a quebra do preconceito contra a substância. Porém, a principal diferença entre um lado e o outro é que o lado do conhecimento, o lado da ciência, tem aplicado o medicamento em um sem número de pacientes com as mais diferentes patologias, obtendo excelentes resultados. E exatamente pelo fato desse assunto ser diverso e polêmico, que o Viver Sem Preconceitos convidou pro bate-papo de hoje, o médico psiquiatra, especializado no uso terapêutico do canabidiol, Pietro Vanni. Com residência médica na universidade federal do Rio de Janeiro, foi no mesmo ano de sua conclusão, em 2019, que ele iniciou seus estudos na aplicação prática da medicina canabinóide. Desde novembro de 2019, ele exerce a função de diretor técnico da Clínica Gravital, que conta com o certificado internacional de formação em medicina canábica. Clique aqui e saiba mais sobre a Clínica Gravital. O dr. Pietro faz indicações de para leitura, quer sabe do que se trata? Visite o site do pesquisador Ethan Russo, clicando aqui e procure "O Livro da Maconha: o guia completo sobre a cannabis", publicado pela Editora Vista Chinesa. Para saber mais, acesse www.viversempreconceitos.com.br e acompanhe nas redes sociais Instagram , Facebook e Twitter .
Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and author. He is the Founder and CEO of CReDo Science www.credo-science.com In this episode, Dr. Ethan Russo talks to us about his new study on CBG, ‘the mother of all cannabinoids', cannabinoid acids, and affordable diagnostics for the endocannabinoid system that provide needed information for patients and doctors. This technology could improve outcomes and product choices for all phyto-therapies, such as aromatherapy, herbalism, and cannabinoid therapy, which Dr. Russo believes can be much more nimble than one-size-fits-all pharmaceuticals in addressing the individualized needs of the patient. Previously, he was Director of Research and Development of the International Cannabis and Cannabinoids Institute (ICCI) based in Prague, Czech Republic: https://www.icci.science. Medical Director of PHYTECS (2015-2017), a biotechnology company researching and developing innovative approaches targeting the human endocannabinoid system (http://www.phytecs.com), and from 2003-2014, he served as Senior Medical Advisor, medical monitor and study physician to GW Pharmaceuticals, United Kingdom for numerous Phase I-III clinical trials of Sativex® for alleviation of cancer pain unresponsive to optimized opioid treatment and initial studies of Epidiolex® for intractable epilepsy (https://www.gwpharm.com). He graduated from the University of Pennsylvania (Psychology), and the University of Massachusetts Medical School, before residencies in Pediatrics in Phoenix, Arizona and in Child and Adult Neurology at the University of Washington in Seattle. He was a clinical neurologist in Missoula, Montana for 20 years in a practice with a strong chronic pain component. In 1995, he pursued a 3-month sabbatical doing ethnobotanical research with the Machiguenga people in Parque Nacional del Manu, Peru. He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, in Medicine at the University of Washington, and as visiting professor, Chinese Academy of Sciences, Harvard University, and Johns Hopkins University. He is a Past-President of the International Cannabinoid Research Society and is former Chairman of the International Association for Cannabinoid Medicines. He serves on the Scientific Advisory Board for the American Botanical Council. He is author of Handbook of Psychotropic Herbs, co-editor of Cannabis and Cannabinoids: Pharmacology, Toxicology and Therapeutic Potential, and author of The Last Sorcerer: Echoes of the Rainforest. He was founding editor of Journal of Cannabis Therapeutics, selections of which were published as books: Cannabis Therapeutics in HIV/AIDS, Women and Cannabis: Medicine, Science and Sociology, Cannabis: From Pariah to Prescription, and Handbook of Cannabis Therapeutics: From Bench to Bedside. He has also published numerous book chapters, and over sixty articles in neurology, pain management, cannabis, and ethnobotany. His research interests have included correlations of historical uses of cannabis to modern pharmacological mechanisms, phytopharmaceutical treatment of migraine and chronic pain, herbal synergy and phytocannabinoid/terpenoid, serotonergic and vanilloid interactions. He has consulted or lectured on these topics in 44 US states and Canadian provinces and 44 countries on six continents.Useful Links:https://credo-science.com/projects/CBG StudyCReDoEndo DNA testsEurofins worldwide testinghttps://ethanrusso.org/category/library/ To learn more about plants & your health from Colleen at LabAroma check out this informative PDF: https://mailchi.mp/2fe0e426b244/osw1lg2dkhDisclaimer: The information presented in this podcast is for educational purposes only and is not intended to replace professional medical advice. Please consult your doctor if you are in need of medical care, and before making any changes to your health routine.
The cannabinoid Cannabigerol (CBG) is so new to being studied that most people are still unclear what varieties of relief it offers. On this episode of Shaping Fire, host Shango Los welcomes back neurologist Dr. Ethan Russo to discuss his new study published this week compiling patient uses for cannabigerol, the specific ailments CBG works for, and the quality of patient results.
The cannabis literature I'm reading daily is quite interesting but so are the back stories of the doctors and scientists doing the work. This episode highlights some of the fascinating medical professionals writing resource books and white papers and giving public lectures and conferences open to everyone… it's a phenomenal moment in history to be learning about this plant. Join me for a little book learnin by the pro's… And find all the books I mention below in the show notes. Enjoy the list… it's ever hanging and growing. Dr. Dustin Sulak, DO, healer.com. Dr. Michelle Ross, PhD, https://drmicheleross.com/ Dr. Angie Krause, DVM. https://boulderholisticvet.com/ Dr. Genester Wilson-King https://victoryrejuvenationcenter.com/dr-genester-wilson-king. Dr. Raphael Mechoulam https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593926/. Dr. Ethan Russo. https://www.linkedin.com/in/ethan-russo-md-468b19a. Lester Grinspoon. https://www.amazon.com/Marihuana-Reconsidered-Grinspoon/dp/0932551130. Ed Rosenthal. https://www.edrosenthal.com/ Michael Backes https://www.amazon.com/Michael-Backes/e/B00J4LMK22%3Fref=dbs_a_mng_rwt_scns_share Michael Pollan https://michaelpollan.com/ HoneySmithWalls.com for that Dear Dr letter. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/cannabaverum/support
Hello gut check project fans and KB MD health family. I hope that you're having a great day soon to be joined by my awesome co host, Dr. Kenneth Brown. It's time for episode number 61. And today's episode, I'm just going to ask everyone, no matter what part of the spectrum that you come from, come with an open mind on this episode. This is a fantastic episode very, very informative. Our guest today is Michael ruark. He is the lead strategist for only one of three licenced medical cannabis companies. Good blend medical cannabis. And yes, that is THC, which is utilised as a medicine for specially designated criterion. And they update it every single year. So September 1, which we just recorded this right before September 1, there's actually a whole new list of medical conditions, which are now legal to be treated by medical professionals. And believe it or not, they have a network of already over 500 positions throughout the state of Texas since 2018, which are licenced and actively dispense medical cannabis. And good blend is one of those companies. So Michael joins the show today to really answer some fantastic questions. And Michael's an amazing person in his own right. He's, he's got a an electrical engineering degree from Stanford as well as his master's he served in the US Air Force, he led a team at National Security Agency, the NSA. I mean, this man is no slouch, he came to this profession to this company. By no mistake whatsoever. He simply doesn't want to just do good. He wants to do great by the citizens of Texas and simply help people live a better life. There's a better way for some of the elements out there and he has a very, very strong passion for helping out our veterans and the Veterans Administration. So I don't want to give away everything in the episode because Miko does a much better job of articulating all of that stuff. So let's get to our sponsors, of course are trying to they've been a sponsor for every show and I imagine they always will be because they were created by my co host, Dr. kins brown are trying to get your daily poly phenol is love my tummy, calm, stop the bloating, stop the abdominal discomfort. If you're an athlete, you need paly finos every single day. And I don't know maybe some of us are worried about a virus and I don't know maybe you're interested in things that function is natural zinc on fours. Well, polyphenols are natural zinc ion fours. So anyhow, without saying too much draw your own conclusions at what this awesome natural product can do for you, but go to love my tummy.com load up on your daily polyphenols today. Love My tiny.com artron deal. And of course, KB m d health.com. You want to learn a little bit more about Dr. Brown learn a bit more about his philosophy. And of course connect with his own branded KVM D health CBD go to KB Md health.com. Use code GCP save 20% off of anything in the store that includes Brock elite that includes the signature packages of CBD artron teal, and rock elite, you can combine the whole thing in there KB Md health.com. Sign up for our newsletters. It's KB MD health is actually growing quite a bit. And we've got some new things in store this fall. So keep in contact with us. And of course do you like great food? Do you like food that tastes awesome? Do you have to sometimes worry about though what kind of diet it fits into? Maybe you're paleo maybe you're gluten free. Of course. I'm going to mention unrefined bakery. They've been a longtime sponsor, unrefined bakery.com go to unrefined bakery. And if you think that just because you suffer from celiac disease, that you can't have an awesome cupcake. Or you can't have some awesome tasting bread or some trail mix that you can trust pie crust, check out unrefined bakery, they My wife has celiac disease This is her go to. And it's just incredible food you'd have no idea that they were all specialty foods to fit specialty diets, unrefined bakery go to unrefined bakery.com you can get 20% off of your entire first order. By using code gut check again your entire first order. So low up on bread load up on pie crust load up on cupcakes, are you selling cupcakes are just incredible. No levy cake, I mean like cake and they got great cakes or cupcakes there and I love the unrefined bakery.com check it out. Use code gut check 20% off your entire first order. Okay. Love those sponsors. they've kept the show going But what really keeps the show going just as much is awesome guests like Michael ruark coming up next episode number 61though KB MD health and gut check project fans, I hope you have a great day. It is now time for episode number 61. I am joined by my awesome co host, Dr. Kenneth Brown. And we got a special guest today, Mr. Marcus ruark. Ken, why don't you go ahead and fill us in.5:38 So it's gonna be super exciting show. Today we have Marcus ruark. And this is something that is very, very important. It's important for my patients. It's important for anybody that deals with all kinds of diseases, but I'm thrilled to have him here. thrilled to be here. Marcus, thank you so much for coming in Marcus ruark is president of good blend, Texas, which is headquartered in Austin, Texas, and proudly sells cannabis products that are cultivated and produced right here in the Lone Star State as one of only three state licenced medical dispensaries. Now, Marcus, I saw your bio, this is super cool, you have a very interesting background. And prior to joining good blend, you received your electrical engineering degree from Stanford. Then you received your master's degree at Stanford and I keep saying Stanford because Eric and I both have kids which are applying for college. And when I see Stanford, that's the sort of crown jewel that most parents want their kids to go to. And they like tennis players. And they like you received your master's degree at Stanford in management, science and engineering. Following this, you went on to serve as a captain in the US Air Force, where you lead your team in the National Security Agency, followed by advanced Systems Division of us Space Command. That's crazy. Following that, your bio discusses a lot of other really fascinating things that I want to get into. But before we get into that, I want to talk a little bit about what's not in your bio. Okay, tell me about you. Family. What's going on with Marcus?7:21 Sure. Well, we just had a big week in the ruag family took my daughter to college, which you just alluded to a little bit ago there. She's going to San Diego State nice, pretty excited about that. But also, you know, it's a little bit anxious and first first kid out of the nest, so to speak. So that's exciting. And then my son started up eighth grade first time back in school since spring of his sixth grade year, right when everybody went home for COVID. So very exciting there too, and he's trying out for football. So fingers crossed,7:49 right on, right on.7:51 That's a plate right there. And so San Diego State that's Trojans, she's a Trojan Aztecs, Aztecs. Yeah. I'm learning too. Nice. All right, that's a Southern California Nevermind. Sorry.8:02 So the family, your background, there was this huge section in your bio, we're very clearly you have an entrepreneurial spirit, you have leadership skills, you are willing to push the boundaries a bit and try some different positions technologies. Can you give me what led you up to this?8:24 Absolutely. So after I got out of the Air Force, I was very interested in joining the the high tech scene that was happening in San Francisco. So did that ride around? Actually not the best time for that because it was right around the bubble here is where there was a big crash back in 2000. But that being said, really got interested in bringing new products to new markets, and bringing new benefits to customers who maybe hadn't seen those benefits before in the past. So very exciting, did a lot of startups founded a lot of companies. And then at some point I crossed over into healthcare so a startup in the healthcare space and it hit me then that as rewarding as I thought it had been doing startups in high tech to do in healthcare it was even more special because not only are you starting a company but you're actually helping people right we were helping doctors treat patients better we were helping patients have better outcomes in their in their hospitals stays. So it was really rewarding. And at some point after that, I was able to join a company called Fluence which you probably saw on the on the resume, but they were in the LED lighting space. And I started there to help out with the customer experience for their customer base. And I learned that the customer base was primarily in three segments, customers who are coming to a growing produce companies who are growing flowers, and then cannabis companies and can imagine which one of the segments was probably the fastest growing it was their cannabis customers and so that was entirely new to me the cannabis world and I as you guys have I dove deeply into it the endocannabinoid system the the benefits of cannabis and learned about cultivation and Creation of products and distribution, all that kind of good stuff. And right around, I guess was the spring of 2017, Texas announced the grant of the first couple of licences for the Texas compassionate use programme. And when, you know, I reached out to one of the companies and say, I think I can help you guys here in Texas. And so I came on board as president of goodwill in Texas at that time.10:21 And that's fascinating. So I mean, obviously, it was just natural as a natural progression. You ended up seeing that there was a need, it was certainly new to you. Sounds like maybe correct me if I'm wrong, but you're inspired by things that you don't know enough about, but seem intriguing could help people I'm still learning10:35 and so much to learn in this space still, but but it ends up it's a great match for all that because it's it's technology, right? It's, it's horticulture, and it's it's helping people within today, right was what was what we're here to do is help Texans.10:48 So it's an electrical engineer, I get that you were drawn to the LED space, but then getting drawn to healthcare and now more of a I mean, what would you describe your position at good blood?10:59 I, I'm leading the entire Texas team here. Everything from cultivation, to product development, formulation, packaging, distribution, working with physicians, working with patient support groups, so pretty much everything setting strategy product roadmap and trying to build a great culture for the team here.11:18 So one of the things that we talk about in our company is the why the why the underlying reason why all this is happening, because if you don't have a solid, why then what you're describing, nobody else really will believe in that. But it sounds like you found your y even if you haven't defined your y statement, you found the Y11:37 Well, I can define it for you. It's we are empowering Texans to find their well being right through natural medicines that our patients say work. And it's, it's, it's so rewarding. Now, we have a we have a group of we have a role the company called mobile wellness coordinators, and these are the folks it's probably one of the hardest jobs at the company, you have to be knowledgeable about cannabis, the endocannabinoid system, talking to patients, so you have to be bit of an extrovert, right? It'll talk to patients. But you also have to drive across the large distances of Texas to deliver medicine to patients doors. So you also have to be a bit of an introvert there to be happy listening to podcasts while you're driving. They have the best job in the company, though, because when they're making that second delivery to a patient, they get to hear how that patient did they could hear the patient testimonials, and they're incredibly rewarding. And it's I feel really almost envious that they get to do this. But they're they're so nice to come back and share their stories with us after they've had these amazing conversations.12:38 So where are you with the company before they ended up having their first dispense of their certified? Yeah,12:45 I've been with the company since 2017. We served our first patients in early 2019. Okay, and what12:52 was it like? What was the anticipation like to get your first patient that had been referred in and and bringing those physicians on board to do that here in a state that didn't do it before?13:01 Well, I think predict my answer was huge and hugely rewarding. Like I said, it's this, the testimonies we hear are fantastic. And as we've come to market with even a wider set of products, different ratios of CBD to THC, different terpene profiles, were able to help more people were able to give prescribing doctors more choices, and patients more choices on how they how they help themselves.13:28 But it just seems like it would be a really cool opportunity to paint a picture of how you feel like you're going to be able to deliver something that maybe a physician doesn't feel like they've got a total grasp, because that's why you would offer an alternative. And then now you've recruited them to go now then just a new novel way, but prior to your launch wasn't really necessarily well embraced. How hard is it to get that message and get physicians to want to buy in to do that?13:54 It is still a challenge today. Sure. And one of the reasons I'm so excited that you invited me here today is because one of my number one missions right now is to try to get the word out to increase awareness. I suspect. We don't have a random text in here right now. But if we grabbed one walked outside in the heat, and ask them if cannabis was legal in the state of Texas, most likely they're gonna say no. And even for the patient groups where it is legal right now, most of them don't know that it's legal. So our number one job right now is creating awareness growing the number of Texans who are aware that they have this treatment available to them. And I really appreciate being on a show like this to help get the word out.14:32 What I think is so cool is that somebody with your pedigree has chosen to do this and now finding out why you chose to do it, which is you got into healthcare, you had the opportunity to do these, these other companies where it could have just been about financial reward. But once you got in and saw the impact that you can have that then you chose to do this with that message of we're going to empower people to take, take their health over what was your statement again,14:57 you're going to empower empower them to take charge with Their own wellbeing,15:01 empower them to take charge of their own well being. That's something that I try to do as a physician all the time. And so many times, it's limited because of the insurance plan because of lack of funding because of lack of efficacy. Sure. So I'm thrilled that Texas decided to do this because we've been waiting to see this happen. I've talked to my colleagues and other states, where medical cannabis is legal. And they tell me about the success that they're having with their patients. As a gastroenterologist, when I looked at, let me just pick a patient population, like my inflammatory bowel disease patients, I'm open to discuss things I I'm more of a functional type person. So I will ask these questions. And if somebody has Crohn's disease, and they're between the ages of 18 to 40, I just say, Are you using cannabis for your health? And they'll stop and be like, yeah, how did you guess? Yeah, I mean, they just go, yeah. And because they're on forums, they're talking. And I said, well, it's pretty exciting, because I think we're headed that way with Texas. And I think that we can make this so that you don't, so that you can have control over this so that you can actually empower your own health with this with products that are meticulously cultivated that have Certificate of analysis that you don't question, which is what good blend is doing. Right. Right.16:23 Well, the other the other message I'd like to get across and it ties into what you just said, is that it's actually easy to do, it's easy to get into the programme. So right, not only do they do Texans not know what exists, but if they do, they probably think it's incredibly difficult to get a prescription and to get product and to be able to afford it. And that's another message I would like to leave with folks is that it, take a look into it, right? Go to good blend.com because it's actually easy to get signed up and get to be part of the programme.16:48 Oh, we're gonna get into all of that. I have a feeling I want to like, where do I go? I love I love talking to people that have been there done that, that have degrees, like you have that have seen so many things. I want to know, you know, what Goodwin does where it is. But I think one of the most important things that people have to realise is that you've got very, I've been to a programme and I've met the doctors that showed up to the programme. And I've talked to paediatrician, psychiatrists and pain doctors here in Texas here in Plano, not just I'm not going very far out. And they told me the effects they're having on their patients. And these are smart people, somebody like you, also extremely smart, we start validating this whole industry and start shedding that kind of negative feeling that people have carried over over the years, obviously, other states are a little more advanced. But even my patients today, we had a 65 year old woman that is quite miserable from an autoimmune disease. And she just said flat out, would you care if I started smoking weed, and I'm like, not only do I not care, but I'm going to send you to a doctor because one of your diseases qualifies you, at least right now on this fairly limited set. And we'll talk about the different programmes, which are easy to get into and all these other things. And she just completely was like, You're kidding. I'm like now and these are, then you start briefly talking about ratios. And it's not about you know, smoking yourself, so you can't move on the couch. I just18:22 want to add to that, because where she is and where she finds herself. And this is why I think what company like good blend really bridges a gap that needs to be bridged. And that is, the reason why she asked or was hesitant to bring up the use of marijuana is because probably up until a certain point she felt shameful and trying to find a solution. And finally, she worked up enough nerve to finally throw it to Ken and say, do you mind if I do? So how long had she been sitting on the fence before she finally worked up the nerve, because we've seen it before. She's not a stranger to the clinic, to work up enough energy to be able to do that. And what I think is great about a company like good blend is stop waiting, we want you to feel better. And there's actually an easy pathway to do. So it's kind of how you see the the access there. Absolutely.19:10 It's it's one of the reasons that we try to have a vast selection of products that feel a little bit less intimidating. Right? So we'll probably get into that later too. But everything we can do to help folks out I mean, I'm actually kind of feeling bad for this person. Right? Because like you said, How long have you been sitting on that and not sharing that and she could have been helped a lot earlier. So yeah, and Texas is making really good strides there. Every two years. I have a legislative session and every two years we've been expanding the programme so I'm I'm very optimistic.19:43 It's if you are knowledgeable about this, so Eric and I got heavy into the CBD. Yes. area when CBD was still people were being arrested in Iran a foreigner here Yeah, Marin County. Over in Fort Worth. They were getting arrested. And I'm like I call Eric I'm like there's another person like what are we doing here? endocannabinoid system. This is perfect. And when you start talking about I'm like this person has an Endocannabinoid deficiency. They've got these chronic diseases, we are just putting band aids on all of these things, including pain meds. If we can get their endocannabinoid system back to balance, it is something that they need. If I have an asthmatic that shows up and they're wheezing, and I say you the only thing that that that is allowable under your plan, the only thing that's allowable in this, I'll take it back one second. Simone Biles, oh, yeah. Alright, so Simone Biles, this is and this was shared, I didn't I haven't talked to her. But it was viewed on a couple different articles that seemed pretty credible. It makes sense. Regardless, it different countries have different rules. Japan does not allow ADHD medication to be taken. She's been on ADHD medication for most of her life. So she goes to the Japan Olympics. And nobody's discussing that she couldn't take that it's a banned substance in the country. It's an accepted substance in the Olympic Committee, because it's an exemption, because they understand that. So she goes there. And everybody's like, what she's lost her train of thought and everything. So imagine if you can't get the drug that you need or the product that you need, and it's available right there. But somebody is putting a wall that's right there, if you're an asthmatic, and you're wheezing, and I can't give you ventolin inhaler to open up your Bronco airways because guess what? ventolin and bronchodilators. It has to be an exception. If it's if you're on the Olympics, like you have to get it exempt. Otherwise, it's considered a enhancing thing. There's things like that that are on that. You know that that's why you get NSF certified for different things, right things. So this is one of those deals where I'm like, if you're a diabetic and you need insulin, or if you need Metformin, and you can't get that, when I look at some of my patients, I'm like, Oh, my gosh, a beautiful balance of your endocannabinoid system may correct 90% of what you have going on, and we can take these eight drugs away. That's what I'm excited about.22:14 Yeah, so I have, I have a theory on this, which is that well, and partly this may end up being preaching to the choir, but it's my understanding that the endocannabinoid system is not well taught in med school, if at all. And if that's true, that means you have to learn it after you graduate. But it also means you may have some scepticism about it, it was only discovered in the 1990s. Yeah, I mean, how can we couldn't do better and discover before them, but that Okay, so it's discovered in the 90s. It's really important, right? And I've heard you guys talk about it a lot. But it is the I call it the it's like the conductor of the symphony. So it is conducting all the other systems in our bodies. And it's telling you that when to get a little louder, or that when to slow down. It keeps everything in balance. And a word you guys use frequently is homeostasis, right? It helps maintain that. And yet I was in a doctor's office the other day with my daughter had to get a COVID test before being allowed to go to San Diego State. And on the wall, this doctor's office you guys probably have to is the systems of the body. Right? It's got the skeletal system nervous system. And I look pretty hard on that poster, it could not find the endocannabinoid system. So to me, that kind of said, everything23:23 is that surprising. And it's unfortunate because it The end result is what we have now. It just simply becomes ignored. And then it becomes taboo. Because if it's being ignored, then maybe it's not acceptable to talk about and it's not acceptable to talk about then you have patients who are fearful for bringing forth an idea for a solution and then we're just slowing recovery when in fact, I mean, I'm not an advocate saying that THC is going to solve everything for anybody. But that doesn't mean it won't work for someone.23:51 We've talked about this before that I believe I'm a gastroenterologist I focus on the gastro anthological system. There are neurologists there are endocrinologist cardiologists, we will have an Endocannabinoid ologists because that is something that people have to get on board to get on board with. There's when you like First of all, a quick side note I suggest everybody after this is over go to good blends website that website is great. It is filled has so much information. So much great information about the history about why it became sort of tucked under the rug about how it was manipulated on a political level and then ultimately about how all these other cannabinoids are involved. So it's I don't know if you can't see it, it's way over there. But I purposely put I put a terpene in there we got lemonade being diffused right now so we can stay mentally clear. You know, terpenes being involved in all this. So as an induction as an Endocannabinoid ologists we're going to get to the point where we'll be like okay, well tell me what your Oh perfect. Sounds like You need some assistance with this. This is probably the blend that you need. This is more of you need a more CBD front heavy with immersing terpene to calm down and one thing in the morning. Yes, absolutely. And the fact that it's all natural and and does that.25:19 You want to repeat that. Just fixed my. We knew it didn't pop right back. I25:25 know what? No, I just said that. I think an Endocannabinoid ologists will eventually be able to fine tune what people take based on the terpenes. And Jen, and you mentioned,25:38 you mentioned maybe one thing in the morning, right to get you ready for your day and another thing in the evening to help you get ready for bed.25:44 Absolutely. And if we could get to that point where people are doing this, then they're like, okay, or as needed. The delivery systems. It's like, Okay, I'm a little overwhelmed right now I'm feeling really anxious. I just did a little something to cut this off. And non addicting all these other things. And Eric can attest to this. When we see these patients and we cringe every single time how many people show up young people. You look at their med list and you're like holy cow that Xanax, that's three different antidepressants. You got a muscle relaxer. How maybe Ambien will frequency so much Ambien, so much other sleep medicines. But let's look at the addictive potential of some of these medications, ultra opioids and benzodiazepines almost criminal, what has happened with these addictive medications that we know they're addictive, but without anything else to give them and you have a patient that's there. And as physicians and healthcare I ultimately want to help people and I have given opioids and I have had the discussion with them. Like I understand you're in a tremendous amount of pain, I need you to sleep. I'm willing to give this to you for a very short period, because I feel like if I can get you to sleep, your pain will be markedly better. And we can stop these other things. As somebody who the world's now not that recent, but five months or so ago, I had my first real neck injury where the pain was an I've redefined my pain scale kind of thing. People go, Oh, that's an eight out of 10 I really thought stubbing my toe. redefine it. And we've talked about him before but Wade McKenna, an orthopedist, you know, he told me he's like, Listen, I'm gonna, I don't I don't like, you know, hitting you with a bunch of opioids and stuff like this, what we really need is to call the muscles down, I'm going to give you a long acting, benzo for days, take it for four days, stop taking it after that, because your muscles will calm down at that point, there was a plan, there's a plan to get me on as a plan to get me off. And he purposely said, I don't mess with these opioids. Are you kidding me? As an orthopaedic surgeon, and when if we could sit there and say, okay, you a patient comes to me, I'm a, I'm a primary care doctor, and somebody has a significant injury. And so tell me what the biggest thing about this. It's the anxiety of knowing that I don't know what's going to happen, okay, then you give a blend, which is more effective on the anxiety, tell me what's happening here, the pain keeps me up. Okay, let's do this, we now have the opportunity to treat these symptoms that ultimately may or may not need some other intervention. But we know it's not addictive. We know that it actually has. And now we're going to get into the science of it. But we know that it actually has these different properties that help decrease the inflammatory processes by blocking p parganas. by blocking these different pathways, g couple proteins, we can get all sciency about it. But the reality is, I don't do that with my patients, I say, Tell me what it is that's bothering you the most. Let's see if we can give you something for that. That's the beauty of what you're doing right now. Good blend has the ability to take these natural molecules in different ratios to help in different scenarios. Totally agree.29:15 I mean, that's actually hit you reminding me it's kind of dissonant disheartening to look at a patient's med list when they come in. And there's a bunch of things kind of like what can just describe, and we're almost used to the polypharmacy or the or the multiple meds that are all listed there. And truly, knowing that a natural alternative could probably reduce that load. So we're playing less of this chemical warfare with this patient because it's almost a new we're kind of hinting at it earlier. It's almost like you're taking one thing to balance out the other thing that I've just gave them this new thing, and you're almost always chasing rather than actually treating and then and letting them be themselves.29:59 So we are getting that feedback from patients which is that once they've been on our medicine for a while they're their drug list is decreasing. Tell us I've we've had we have been able to stop these three things and now I'm down to these things I've been able to reduce the dose of these things. And if you I'm not, I'm not asking you to do this, but if you want to go Oprah on me and ask for patient testimonials I I made, you know, their tear jerker is really, in terms of helping things we're able to do with people.30:25 Well, you know what, yeah. Do you want to do it? Brian? Yeah, yeah. Tell me about one word, somebody, it made such a profound difference in their life that they couldn't hold back.30:34 Yeah. So there's a there's a patient we have that has terminal cancer. And that was a hard just that you guys have these conversation. I don't, it was a hard conversation for me to have. But he had a great outlook on his life. And he started taking our medicine, and he was able to cut back on his opioid use. And the way he described it to me was, it's not just good for me, it's really good for my family. Because on opioids, I'm a zombie. And with your medicine, since I've been able to decrease the opioids, I can be myself around my family my final days. So they're hard stories, but happy stories. Another mom said to us, her son had so many seizures a day that, and he had so many anti seizure medicine. He was kind of just there, right? But on our medicine, he was able to stop taking some of his anticonvulsant medicines. And he said, how this is when it gets me he says to us, one day, Mom, I have feelings.31:34 Wow.31:36 That's, I mean, what a What a crazy thing to have to lose as a kid the ability to basically participate in life because it's being taken away from you by a chemical that up until now was necessary, because you you obviously can't just sit there and suffer from seizure activity over and over again, that's, that's dangerous in and of itself. Right. But not knowing that there's a better alternative is honestly criminal. It's criminal, not to know that there's a better solution than just taking anticonvulsants to control I'm assuming epilepsy or something similar to32:09 right. So that's, so that brings up a really good point that mom, I have feelings. These medications have side effects, and the side effects that most people don't talk about as the pharmaceutical medicines, the pharmaceutical medications. Correct. So I get so many of these patients that are on polypharmacy, because so many of them have anti parasympathetic, meaning they affect the gut. Almost all of them do one way or the other. Oh, I have diarrhoea. When did that start? Six months ago, I see you're on Zoloft. When you start Zoloft. Seven months ago, huh? I have so much conversation What's going on? Oh, you're on the opioids? Oh, I've got a date all there. I'm fully aware that there's completely these are necessary drugs. But my job when I during residency. Some of us were chosen for basically treating older people. So I went to the older people clinic. And so my the technical term for it, that's the tactic. The older people,33:21 obviously, yes.33:23 Yeah. The layman's term is gerontology. But yeah, but we call it the older people. OPC. I would sit there. And as a resident, I'd looked at these lists, I'm like, you're 90, you're still here. Why do we care about your cholesterol that has this effect on this? And this? Why are you on this? Right? My sole job I viewed in that clinic, was to just get people off medicines, because the side effects at some point are just completely Yeah, outweighing that. And that was just a lifetime of going to this doctor that doctors cardiologists going to give this guest route, they just keep adding up. They just keep adding up him. Somebody shows up with a list of this. None of these drugs have ever been conducted in a trial, where they're all together. What happens then? We don't know. Well, I'm dealing with that now. And I've got a nine year old person and just every time they'd come back, they'd be more alert more. If you made it to 90. You're a baller. You've done it right. You deserve to drink, what's your mama smoke,34:28 what you eat what you want, do whatever it is. And they would love that by the time they were there. Yeah, they start having fun again, and it was just about getting them off their drugs. You got to hit on something, though. And maybe you seen this because you said you've seen a show or or two but something that we've had we have hit on is lifespan, and life expectancy is just a number. But what's way more important truly, to enjoy those numbers is to have a good health span. And to be able to function and participate in life if you're going to live it. You may have It'll be involved in it right? How do you How does? How does your company view healthspan? In relation to to that?35:09 I would say it's similar to the the things we've been talking about, which is if you can, if, if there's, if there's an opportunity to live a higher quality life, right. And there's a natural way to do that, and to get off some of the pharmaceuticals that maybe are causing some of the side effects, and you can live a happier higher quality life. I mean, that's, that's what we're here for. Right? It's kind of what I talked about well being that's exactly what we're here for.35:36 So if you gave two quick testimonies, one, obviously about someone with epilepsy and one from somebody who was suffering from terminal cancer, yes, what other what other ailments to kind of focus on as it stands right now?35:51 The so there is a treatable conditions list on Texas. And it is, it was created by statute. As you know, it started out in 2015, as intractable epilepsy, that was the only treatable condition. In 2019, the programme was expanded in a significant significant way where a lot of new conditions were added. So terminal cancer, autism, ALS, Parkinson's, spasticity, a whole giant category of conditions under the headline, incurable neurodegenerative diseases. And that has a list of about 300 things underneath it. So it was pretty significant expansion. And I would say across all those, all those treatable conditions, we're hearing positive testimonials.36:36 That's fascinating. And actually, I had glanced at it, I don't think that they cannot have spent any time on it. But I did notice that there was autism. And I don't know that you do you have a testimony or not. But it's definitely something that's near and dear to this guy in our research, just to polyphenols but he's made he's made no mistake about it. There's a play there with with cannabinoids as well.36:59 Yeah, I'll give you my I'll give you my take. In fact, we work with a great asset. She's been on the show before Angie cook. And she wrote up an incredible which I've yet to publish, partly because at the time, people were being I mean, Texans don't even I, I can go around right now and talk to my patients about CBD. And I've got CBD all over my office. And they will be like, Oh, boy, no, I'm not into that. And I'm like, let me explain that to you real quick. And let me explain this. Do you have any chronic condition, whatever, like, Well, yeah, totally do well, and then they end up, you know, purchasing it and saying, yeah, it made a huge difference. And it comes down to that rebuy rate. So as a business person, we know that I've got a almost 50% rebuy rate on Tron teal. And this is like, you know, worldwide. We know that that works. Because as if anybody's ever been in the pharmaceutical industry, I prescribe a drug and they come in and I'm like, Did that work and their trials that you know, the studies show? It's 8% better than placebo, whatever. So it all comes down to does the person want to come back and purchase more? That's To me, that's the that's where the rubber hits the road. My move towards autism became very personal. When I had a patient that brought her son in and he had become I'm an adult doctor, he had moved on from paediatrics to adult. And she said he's becoming almost impossible to take care of when he eats. He cannot communicate. He flailed he gets almost violent. And he's, you know, he's 16. Is he just becoming a young man, and this is getting really bad. I said, Listen, I don't know a whole lot about autism. But I do know that. You said when he eats, let's treat his gut. Let's fix his gut. And I'm just now getting into something where I believe it will play a role. And I put them on CBD. And now looking back, we're going to look at this, I'm going to be sitting in a lecture someday and an endocrinologist will have the exact thing to give that person. But right now that was best I could do is your mother shows up three months later, crying. And her son is communicating, not high level, but she's like, he's like, Hi. And he's talking. And I'm like, How do you feel? And he's like, you know, good. And she's like, This is crazy. It's been 10 years and I have not seen this person. And like, I don't know if it was the fix in the gut. I don't know if it was the CBD regardless, I think it's both. And that's where it came in. So then Angie did this incredible write up and maybe we can team up with your people to get it published, but it's like 50 pages long. It's super sciency. It's all about autism and the effect on the endocannabinoid system. And when I go to my colleagues and they say there's no science on this, we share a Mandalay capability, what Mandalay is. So we share this, the repository of journals that are out there are published and we've got a whole folder on There's a whole folder on CBD a whole folder on cannabis and cannabis. And the sciences, they're animals to humans. The problem is the science in the United States is not here the science that is recognised by our journals here, because, and we talked about this, that people don't realise that it was approved if you're going to study cannabis, and Michael Pollan was talking about this, the author Michael Pollan was talking about this, that the cannabis, which is approved by the FDA to be used in studies. It comes from one place, one place some crap lace, it's like 60 years old. Yeah, it's been around, and kind of just40:40 shit marijuana. It just it's not indicative. It's not similar to the kinds of Medicinal Products that you're gonna get.40:47 Yeah, exactly. This40:48 is what it is, and correct me if I'm wrong, but this is, this is what all sanctioned and allowed us research is done on is basically just this one lot. Correct.41:00 or from a federal perspective, I believe that's right. Yeah. Having said that, very exciting news in this most recent legislative session. Nice. The statute that they added to the statute that Texas can start its own research programme. So the department State Health Service real for real so yeah, they're they're writing the rules right now. And yes, it's very exciting. So Texas cannabis research. Does part of the Texas compassionate use Berg did not know that did not know that. And it goes beyond the treatable conditions list. For sure. do research, the research, whoever the research institution is picks what they want to study,41:40 I need people to hear that said a little bit close with money. Which part the?41:46 The research so the Texas compassionate use programme is introducing a research element. And the department State Health Services is writing the rules right now. I think they're even posted for public comment. And it's gonna happen. And so the research, whoever the research institution is, and they provide a list of who can qualify, you pick the condition you want to do research on. You do have to find an IRB. But it's sky's the limit. Oh,42:12 my gosh, that makes me so excited that just that turned into hope for my IBD patient. Yeah.42:20 So just to click and you42:21 get to use our products. You don't have to use the federal cannabis.42:25 Okay, I have been that is exciting having you on just for that one thing. I hope my partners listen to this because ga right now is we're getting close to 1000 providers strong. And in the state of Texas, basically everybody in the state now as part of this one group, to be able to power a study like that could be fan tastic. I have just, I thought that it was completely prohibitive. And Gotta love Texas. Gotta love. We're gonna do it in Texas if the feds don't want us. That's awesome.42:59 No comment on that. Your point about autism, I've had the I've been very fortunate to be able to attend a to medical cannabis conferences in Israel. And then one was in LA. And there's plenty of studies out there about autism and THC for43:14 sure. And that's what this 50 page review that Angie put together, put a lot of sweat and tears into it. And it's something that we should probably team up with some of your scientists to update it because it's about two years old. Yeah. But I was shocked reading it, the level of science, the level of information out there, and the amount of benefit that you can actually do and the correlation. So for me as gastroenterologist the correlation that when the endocannabinoid system is off, it affects all systems. But in my opinion, all health begins and ends in the gut. If you don't have a healthy gut, you ultimately affect the brain. And we've got we've done podcasts on this where we can show that neuro inflammation or chronic inflammation affects f h, which is the enzyme that breaks down your own endocannabinoids. And when you lower your inanda mind, which is the one that you know is your low level keeping you there. It's your body's own equivalent to THC. It's your body's own equivalent. And then on the flip side, when you have to a G which is the spotlight if that's getting turned on all the time, that's your that's like a that's the other portion of the endocannabinoid system. The difference between a Stanford grad and a simple country but doctrine Nebraska is I've used the same example the endocannabinoid system, but you referred to it as a symphony conductor. I refer to it as a traffic cop. Yeah. They're both good. I could say mines. You know what? I won't say. Yours is more elegant to start using that from now on. Yeah,44:52 elegant was exactly the word I was gonna say. So I'm glad you said it is refined and yours is quickie, Martin.45:00 To your point about the importance of the gut. And if you haven't checked out this research, please do. I think you're gonna find it very interesting. There's one of the leading researchers in the field of cannabis is a Dr. Ethan Russo. And he has a I think he calls it. I may begin this wrong, but the grand unified theory, but of course it spells out gut, but it's all about the the brain gut connection and with the endocannabinoid system as a key part of it, and you've you've addressed this in previous conversations, but they're all tied together.45:33 One of my problems that I have had, and I'm curious how you and your sales people have dealt with this, it's the person that I know how to say this. I'm enthusiastic. And it took me a long time I've read vitamin weed, which is a great book, forgot the Michelle Ross, Michelle Ross. That's it. Michelle Ross wrote that she's a PhD. You know, there's Goldstein's book. These books are great. But I had to read them a couple times. The first time I started getting into it before you start going because it's it's a different language. It's that's why I think we're gonna have an Endocannabinoid ologists. My problem is when I have somebody, it's that the vomit of knowledge that I have to keep myself from doing when somebody is like, what's that? And then you start getting into it, and you're like, what's the endocannabinoid system? So I've always I'm a little bit curious, from a business perspective, how you as a company, get into that naive, let's just start with the naive doctor46:38 that says, Why don't know about this? They start with the, you know, yeah, you know, I'm kind of curious. He may not want to divulge everything, but I really kind of want to know how many practitioners throughout the state are actively participating in this programme.46:50 So the state publishes some data about the programme. The most recent date is from July, and there were over approximately 50046:59 Oh, wow, it's much47:00 bigger than I thought. And to be a prescribing doctor, you have to be a board certified specialist, as you are. So it's, it's not every doctor, you have to write you have to be board board certified. And then the patient, the patient count as of July was right around 7070 507,500. That may not sound like much, but it's growing 10% every single month. Well, it'll be one of those things every single and this is in the in the official kickoff was 2019. Right. For the first patients. The first patients were actually served in 2018. Okay, not by us, but okay.47:38 So that is so tip of the iceberg because as a clinician, I went on once I found out you know, one of your sales people that had has known me for a long time as a friend and they got involved with this knowing that I'm involved with CBD and understand the endocannabinoid system. So first thing I did is I tried to sign up well, my specialty is not listed. So as a gastroenterologist, I'm not listed as currently interesting currently, because when I did the whole thing and went through it and tried to I couldn't find that. And then for me, it was a little daunting to say, Well, I'm internal medicine is there on board certified internal medicine, but I really practice 100%, gastroenterology. And I did not want to false under any false pretences as this is, because it's just a matter of time. It's better a short time. So discussing that, from a business perspective, what can I do? As a physician who's very interested in this? help some of the legislation, bring in other let's start, I've got a tonne of questions about that all these little things, but help bring in other specialists are there? I mean, I don't I don't even know I don't even know, like committees are?48:55 Well, hopefully, a discussion like this helps. Right? For starters, right? It was one of the reasons. I mean, hopefully doctors watching this who are board certified specialists who are intrigued and have heard how much this can help will apply to get the programme. It's very simple for doctors to get in. You, you just provide your Texas Medical licence number, I think and your board certification number and the Department of Public Safety checks those two things. And that's pretty much the extent of it, you become registered and at that point, they very much leave things up to the doctor. That's one of the great things about the programme is Let's trust the doctors.49:33 So in this case, not knowing enough about that. I'm like, Well wait till my specific specialty, it just there was neurology, oncology, pain, internal medicine. There was a lot of specialists so if there's a physician listening to this, go check it out, because more likely you're there. I'm just saying that gastroenterology was one of the few that was not listed.49:55 I can I can certainly bring that up with them and ask, you know, we can get If we can get that specialty added, I'm surprised it's not on there.50:02 That was eight months ago, nine months ago, something like that. Maybe it is I haven't checked recently. But I thought, well, it should50:11 be one of the things I think you should be is. And I actually learned this from you in our very first phone call. One of the treatable conditions, which I don't think I listed before is called spasticity. And it is unlike everything else on the list for your very intelligent audience. They know as soon as I say that they're like, which one is not like the other spasticity is a symptom, am I correct, and everything else is a sort of a disease or condition. And you informed me that much of what happens between the mouse the top and the bottom, you know, by the way, for those who don't know, if you get on a phone call with a gastroenterologist, it can get like, it was unexpected. I was not expecting to have that conversation. In my day. I'm on the phone. I'm like, Whoa, because we went top to bottom, or you did, but apparently, it's all a lot of it's muscle. And there can be spasms in that muscle spasticity in the muscle, and that is a treatable condition.51:03 It's nerves innervating muscles and the muscles if they go into spasm create tremendous pain. And if you're ever worked in ER, and you ask an ER physician, what's the what's some of the most common complaints, it's abdominal pain. Now that can be all the way from a perforated bowel appendicitis. But a lot of times people just get labelled, Oh, you've got a bug or IBS, and then they get sent out. That's it's a huge chunk, because it covers so much territory. So yeah, for spasticity. If we can get the spasticity handled, I can help so many people, my cebo people. So if you have small intestinal bacterial overgrowth, one of the reasons why you have so much pain is because the bacteria produce gas, which stretch the intestines, in a reflex, the intestines trying to track back, that's a spasm, this is reminiscent of our phone call together. except you're eating at the time. When somebody poops like this, you want to make sure that52:06 I'm kind of curious about if if, in the new, you put it in these words, if a if a interested position, or one on the fence, even we're, we're considering this, and you've already talked about what it takes to get approved. So let's talk a little bit about what's the experience like to be that practitioner. For one, you write a, an opioid, or what something has a highly addictive property, or even if it's classified that way, it's called a controlled substance. And then in Texas until recently, we always came with the paper, triplicate, I mean, there was a there was a form to do so. So what's it like? What's the process for the writing of the prescription? And the experience going through your company? And what is the physician See? How is it dispensed? What's the fall ill insurance your ongoing?52:52 Sure. A challenge for a patient can be finding a doctor who can prescribe we've tried to help with that by we have we have a virtual clinic on our website. So if you go to good blend calm, you can actually see a doctor through telehealth, it's one of the very great things the state of Texas has done is enabled telehealth for this programme, which is super exciting. You can see a doctor through a telehealth appointment or you can go to a doctor's office and see them there. They're either either the doctor will diagnose you with one of the treatable conditions, or you bring your medical records from a different doctor who's, for instance, if you had a patient and in their chart, and you'd put spasms of the gutter specificity, or they could actually take that chart to another doctor and get a prescription.53:37 That is fantastic video. So as somebody who's learning and I'm risk averse, and all these things, I just don't want to I want to make sure that I follow the lay of the wall, which is why I stopped when my own specialty wasn't there. That is fantastic to know that I can say look I can right now I'm not comfortable doing it. But I truly believe that you could benefit from this, please go to this website. Set up a virtual visit. Show them this note, fax them my clinic note 100% Oh, that's54:08 easy fan. TAs this, that's awesome news because it actually allows a physician on the fence or is worried about blowback from maybe their own partners, they can now safely dip their toe in the water and say, Look, I've got a pathway for you to get we have doctors that do this all the time.54:21 Oh my gosh, that is great. You're exactly right. When I first started doing CBD, one of my partners grabbed all my all my pamphlets and said brown wants to sell weed in our clinic. That's fine, but I'm not taking part of it. Not a joke. So and then if I actually,54:37 you know because there's just this much misinformation and and the people don't educate themselves. That is awesome. Because what are we talking about here and you said it you started off this interview. We want to help people and the people we want to help as the patients and you don't care if you're getting the credit as the doctor who is being in this position to do Do that. This is about the patient who comes in and says I hurt or I can't get over it or I as you said with the with the kiddo I can't feel. Let's get them on a route to do so if you're uncomfortable doing it's fine. Let them take what you found with them and then and then head over to G website55:18 not to digress really quick. But when you said that I can feel for the first time imagine your child who you love dearly that has never been able to express love can then express that because of this because you got them off these meds as living that's living. Yeah. That's, that's awesome.55:38 Yeah, it's fantastic. Oh, and I know you didn't mean to digress, but I am curious though. Yeah. Once they rot55:44 that continues a journey for Yeah, sure. So that everything the patient record for the programme lives on a Texas website. It's the it's called curtsy u RT, the Compassionate use registry of Texas. A prescribing doctor would go into it's it's an online service, but you go into you log into that service. And then you create a new patient profile for your new patient. And then you create a prescription for that patient. And so your prescription you have they give ultimate flexibility for how you want to write this prescription. The ones we recommend are flexible to give the patient flexibility. So you would specify here's the milligrammes of THC, I think would work for you over a an X day period. So this prescription is going to exist for 30 days, 60 days, 90 days, we recommend 90 days, because I think one of things we've learned from the the, like the CVS is in the Walgreens of the world is that you can write that longer prescription you're going to get better compliance for for the second round of dispensations, but so 90 day prescription, this much THC and milligrammes and then you have to specify the means of administration, you can get very specific with that you can say, it's got to be tincture, or got to be a gummy, or there's a box that says, I think it says other any means other any means. And then there's a notes field. And so what you could say to a patient is, so you do all that. And you could say I recommend you start with this in the morning, this in the evening. And if you want to dabble with your, you know, try, try this and see how it works for you, you can try that too. So that all exists in an electronic record. The next step then is for the patient to contact, good blend. And then we they tell us their identifying information, we pull up that patient record and that prescription and we're able to dispense against that one opportunity for improvement in the programme. And some doctors do this some don't is you think about it, when the patient leaves that appointment. You know how this goes, I can't I can't remember really half what a doctor says when I leave that appointment, cuz it's a high stress, time. And when you get home, I have trouble remembering what the doctor said. So we do recommend you give the patient something that says, here's what I'm prescribing you, or you send them a follow up email and says, here's, here's the prescription I gave you, otherwise, they don't remember what you're prescribed. And then we're the ones reminding them, Hey, your doctor prescribed X, Y and Z. But that's the process. So you see a doctor doctor interest, the prescription into the compassionate use registry of Texas patient contacts us we dispense against that in terms of getting the medicine and products to patients. We offer a lot of different ways to do that. We started out as 100% a delivery model. So we were delivering to patients homes. We've recently added the the ability for patients to come into certain doctor's offices and pick up their what they've ordered. And even more recently, we've added the ability. It's almost like a miniature retail experience. But we bring unassigned product into the doctor's office, and a patient could walk right out of your appointment. you've entered their prescription and occurred and we can they can shop right there and buy what they want. And then so a one stop shop.58:50 Let me clarify that really quick. So you're saying that a physician can actually have product in their office and they can sell it directly to the patient.58:59 We do the selling? Yes. Okay. We are there in the in the lobby or wherever, wherever we are and patient comes in and they they see what we have to offer and then they buy what the prescription says and sorry, pharmacy extension, essentially essentially I'm okay. Okay,59:13 so just one small caveat on this journey, so far, so much like, just so that people don't think that a physician is just guessing what the milligrammes are, whenever a new minute, whenever a new medication comes out that isn't cannabis. They utilise representative representatives to go and educate a physician. I doesn't matter if it's a new blood pressure medication. Every blood pressure medication that you've ever taken has had a representative go in and basically detail a physician on that. So I would imagine that there is a detailing process on best practices, things to look for cues. Correct. Thank you for bringing that up.59:51 Yes, we as you would a physician would not be guessing. We have we have dosing guides. In For instance, if you want the prescription to be 90 days long. And you're thinking about prescribing x, we have a recommended daily dose and just multiply by 19. Put that into the prescription. So yes, we, we provide all those sorts of collateral educational material and that1:00:09 kind of stuff. I mean, that's, that's not unique just to cannabis. I mean, we do that literally with every single pharmaceutical that has ever been rolled out. Physicians practitioners need to be educated on it. So this, love this because this is no different. And except for that it is because people have worried away from it. And I think it shouldn't1:00:31 be different, right? And we're getting to the point where it's not sure I got here, you one other way, it's similar to the way prescriptions work in the pharmaceutical side is, if a patient were to call us or, or ask for something that was slightly different than what you prescribed, then we have the ability to contact the prescribing doctor and say, Hey, the patient is interested in this slightly different than what you prescribe. So for instance, let's say you, you check the box for tincture, and the patient decides they want to try our 12 ounce beverage or patient wants to try gummies might be in the same ratio might even be the same dose, it's just a different means of administration, we're able to contact you and say, Are you okay? If the patient gets this instead, and then we just write the note into the look like a little hamster typing there. We just write the note into the, into the prescription.1:01:21 But I mean, that happens with generics and name brands and regular pharmaceuticals, too. So I mean, I think I think it's awesome that y'all it's it's completely your legitimising something that should have been legitimise a very, very long time ago. I love that you'll have that in your model. Yeah, it's1:01:36 transparent. Yeah. I love how that's, that's well. And also, let's, since you brought it up several times, let's talk about these different means of administering. If you have examples, like what what are some of the things that you that you've seen your practitioners have success with that some of the clients the patients seem to like, because a lot of people don't realise A lot of people think oh, I, I don't I just have to smoke it. Right. That's the only thing that that it's there for it. So this is a medicinal product. What are some of the ways? Sure, sure.1:02:06 So we started with started with tinctures back in the our first first couple months and and that was when the programme was in early days of the programme. I should back up a second say. One thing to note about the Texas compassionate use programme is we are capped at a THC maximum currently of 0.5%. by weight. If you know your you know the world of cannabis, you're thinking that's a very small amount of THC. It goes up to 1% starting September 1 based on most recent legislation, but one of the things we realised is that if depending on what the product is what depending what the means of administration is 0.5% can actually be a lot right the heavier the other ingredients are. The more you can get in there more THC you can put in the product and still stay below the 0.5% limit. So we had tinctures for a while and then we moved on to Los Angeles. We were the first company in the state to come out with an edible product like that it was lozenges meant to kind of dissolve in your mouth and for absorption of the cannabinoids after lozenges, we came out with gummies we're the first in the state come out with gummies we have one to one CBD THC ratio gummies and we have five milligrammes THC straight up. And in those gummies we've got different terpene profiles, we've got a sativa profile and indika profile that that's getting our doctors from prescribing flexibility we see you know, common common prescription might be take the one to one gummy, that's sativa in the morning, because it can be more stimulating and it's not you know, it's a one to one CBD THC so you have those working together. But when you're getting ready for bed, take the five milligramme indika gummy which can can be relaxing and can help you sleep. So those gummies really helped with prescribing flexibility. We then came out with lotions. So we've got some topical products, which now again you have to have one of the treatable conditions. But if you also have some other symptoms that could be helped by our medicines, then you're in the programme. Sure you have access to everything once you're in the programme. We launched medical capsules, which is a really nice, very precise dosing product for doctors. And then most recently, we were the first. By the way, all of these were first in the state. We most recently launched our 12 ounce beverage cannabis infused beverage, which I guess I have since I brought pot props, I might as well show the prop. It's empty because right now we don't have a prescription. But all these are getting great feedback I'd say are1:04:47 the most popular. What are some of the other products that you brought. These1:04:50 are all empty, of course there's our gummies here, these are the Texas Orange City, the five milligrammes I got one of our lotion, one of our topical lotion jars, here. Sure. Thank you for asking that question because one of the things I should mention is one of the things we did launch, this is our dream tincture. So it's it's designed with a terpene profile for evening use. Yeah, but one of the things we also did with this tincture, and it's a different bottles that we added, lowers, they can go to our website and see a nice rendering of the bottle. But one of things we did with this launch of the dream tincture is we had a
In this behind-the-scenes conversation, we are joined once again by cannabinoid researcher Dr. Ethan Russo. Russo and a team of researchers recently published a research paper entitled, "Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation" which announced findings that could help explain the physiology of CHS, provide tools for screening Cannabis users for CHS, and lead to the development of targeted treatments for CHS. Throughout our conversation Dr. Russo explains what CHS is, how it compares to Cyclical Vomiting Syndrome, common misunderstandings about CHS, the results of his recent research study, and what we might expect from the future of CHS research. Read the study: https://pubmed.ncbi.nlm.nih.gov/34227878/ Learn more about CReDO Science: www.credo-science.com Stay curious!
We discuss a new research publication on cannabis hyperemesis from Dr. Ethan Russo and Nishi Whiteley, and a review article on serotonin receptors & psychedelics. This episode also offers the opportunity to learn the answers to important questions like, what are the potential risks and benefits of naturalistic mescaline use and what are non-psychedelic psychedelics? We also discuss indigenous populations and maple syrup. The show ends with a new game, Name that Drug! - Dr. Marcu reads a case report about an experimental drug treatment, while guests try to figure out if it was THC, psilocybin, LSD or a CBD extract.Thank you to this episode's sponsor Gooroo Music. Episode's Group:Jahan Marcu, PhD (Moderator) Ethan Russo, MDNishi WhiteleyDel Potter, PhDNigam B. Arora, PhDNews and Popular Literature Links: Naturalistic and Long Term Effects of Mescaline (2:57)Are Non-psychedelic Psychedelic Compounds a “Bogus” Pipedream? and a $27 Million Grant Funding the Project (13:05) Maple Syrup and Indigenous Populations (34:00)Rapid Fire Science Study Links:Serotonin and Brain Function: A tale of two receptors (41:30)Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation(57:00)Today's Game: Name that drug! (1:23:15)Credits:Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Robin Bordow, Intro music by Buddha by Kontekst, Transition Music by Gooroo Music. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode. More at: howtolaunchanindustry.com marcu-arora.com
We had the privilege of sitting down with Dr. Ethan Russo on THE DAY he released his paper on Cannabinoid Hyperemesis Disorder. You can check that out right here
What is Cannabinoid Hyperemesis Syndrome (CHS)?This week, we welcome back Dr. Ethan Russo, physician, researcher, and leading expert in the field of Medicinal Cannabis. In this episode, Dr Russo shares the latest research and findings of the largest study on CHS to date - in which his team identified 6 potential genetic targets to assist in the diagnosis and treatment of the condition.→ View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e120About Dr. Ethan RussoEthan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and Founder/CEO of CReDO Science https://credo-science.com Previously he was Director of Research and Development for the International Cannabis and Cannabinoids Institute, 2017-19, Medical Director of PHYTECS, 2015-2017, and from 2003-2014, Senior Medical Advisor, medical monitor/study physician to GW Pharmaceuticals for numerous Phase I-III clinical trials of Sativex® and Epidiolex®.He was a clinical neurologist in Missoula, Montana for 20 years. He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, and in Medicine at the University of Washington. He is author/editor of seven books and has published more than 50 peer-reviewed articles.ResourcesJoin Dr. Russo on LinkedIn: https://www.linkedin.com/in/ethan-russo-md-468b19a/View Dr. Russo's clinical research papers: https://www.researchgate.net/profile/Ethan_RussoCReDO Science Website: https://credo-science.com/Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation Paper: https://pubmed.ncbi.nlm.nih.gov/34227878/
Russ Hudson is a researcher and consultant who has spent more than 30 years working with cannabis. Specializing in the investigation of terpenes, flavonoids, and the synergistic effects between these compounds and cannabinoids. In this episode, Russ talks to us about the magic of terpene molecules, which he describes as the most universal language in the world. Hudson's primary work is focused on reducing the belief in and reliance on "Silver Bullet" theories in cannabis medicine and therapies. Hudson has spent the last 3 years working with top researchers on the world's largest resource on terpenes and flavonoids; a textbook titled "The Big Book of Terps," along with Hudson's new TV show, "Terp Talk." Information about this book and the related TV show can be found on Hudson's website, http://thebigbookofterps.com/. Hudson also provides executive-level consulting services to the cannabis industry in Europe and the United States, offering legal research, technical writing, licensing, compliance, startup, and other cannabis business development counsel and services. His work has been the subject of a VICE documentary, and is partly detailed in Hudson's cannabis-centric autobiography, "Weed Deeds: From Seed to Sage." The Big Book of Terps: The Big Book of Terps is the world's largest resource on terpenes and flavonoids in cannabis, with more than 1800+ citations, 200,000 words, and 100+ custom graphs, gifs (available online), charts, and other images. This significant work includes information not previously known to the cannabis industry, as well as several discoveries not previously reported in scientific literature. Written by cannabis researcher and consultant Russ Hudson, with Sharon Lund, PhD (Nutritional Epidemiologist), and Gloria Fuentes, PhD (Molecular Biologist), The Big Book of Terps required more than 3 years of intensive research to compile and dissect and features commentary by top cannabinoid and terpene researchers including Mitch Earleywine, Ethan Russo, Colleen Quinn, and many others. Useful LinkTerpenes: The Most-Spoken Language in the World:http://thebigbookofterps.com/terpenes-the-most-spoken-language-in-the-world/ Microorganisms Trained to Poop Terpenes:http://thebigbookofterps.com/microorganisms-trained-to-poop-terpenes/ Terpenes Preserved for Millions of Years in Underwater Wood:http://thebigbookofterps.com/terpenes-preserved-for-millions-of-years-in-underwater-wood/ Terpene-Powered Cars on the Horizon:http://thebigbookofterps.com/terpene-powered-cars-on-the-horizon/To learn more about plants & your health from Colleen at LabAroma check out this informative PDF: https://mailchi.mp/2fe0e426b244/osw1lg2dkhDisclaimer: The information presented in this podcast is for educational purposes only and is not intended to replace professional medical advice. Please consult your doctor if you are in need of medical care, and before making any changes to your health routine.
Today, Dr. Ethan Russo has published his groundbreaking research into the causes of Cannabis Hyperemesis Syndrome. The research team's survey and genomic investigation of patients has, for the first time, identified the genetic mutations affecting neurotransmitters and the endocannabinoid system. In this episode of Shaping Fire, host Shango Los reviews the entirety of the paper with Dr. Russo, including all five of the genetic mutations, the results of the patient survey and why we can exclude causes such as neem.
Jackie is a cannabis educator with a passion to empower women to overcome the stigma and embrace the healing power of cannabis. She is proud to have led well over one thousand individuals in their CBD wellness journeys. Jackie's ResourcesInstagram Accounts: @thehempforce // @naturally.jackieCBD Crash Course Ebook: https://drive.google.com/drive/u/0/my-drivePlanet Canna - cannabis education: https://www.planetcanna.org/Website: thehempforce.comAffiliate Link: https://myeq.com/ code: “jackiew” (you might even have me as your Dosage Specialist!)Jackie's Recommended Resources:- Green Flower Media Courses: https://www.green-flower.com- Project CBD: http://projectcbd.org- Dr. Ethan Russo: https://ethanrusso.org/category/library/- Leafly: https://www.leafly.com✦ ✦ ✦ ✦Use code "PODCAST" at checkout to save 15% on your Follow Your Heart Oracle Deck.Get yours at torirerick.com/shop/followyourheartoracleHosted by Tori Rerick, PharmDPodcast Instagram: @6degreesfromcannabisTori's Website: torirerick.comTori's Instagram: @yourguidetoriEpisode edited by Jacqueline FernandezThis podcast offers health, wellness & cannabis information designed for educational and entertainment purposes only. You should not rely on this information as a substitute for, nor does it replace, professional medical advice, diagnosis or treatment. Consult a health-care professional if you have concerns or questions related to your health.
Some of us come to the power of plant medicine relatively late in life (me for example), while others are practically born into an appreciation of their medicinal benefits. Sarah Russo falls into the latter category. As the daughter of respected cannabinoid researcher and neurologist Dr Ethan Russo, since being a child she has shared his fascination with all things botanical. For over a decade, Sarah was involved with pushing for a change in cannabis legislation in the US, and was very much involved in the formative years of Project CBD. Now living in Ibiza, Spain, Sarah's vision of plant medicine extends well beyond the cannabis plant, and is why she has written the graphic novel, Herbs for the Apocalypse: where plants and punk rock collide in a tale of apocalyptic reckoning. Check out the fantastic website that accompanies the book, which seeks to empower us 'by delving deep into the realms of how herbal medicine can heal and bring us closer to our higher collective evolution.'For more information and to find out how to get hold of the graphic novel go to:https://www.herbsfortheapocalypse.com/Instagram/facebook: @herbsforapocalypseTwitter: @herbsapocalypseCheck out Dr Ethan Russo's fantastic podcast episode explaining clinical endocannabinoid deficiencySupport the show (https://www.paypal.com/paypalme/marybiles71)
For this week’s episode, we had the absolute honour of speaking with cannabis legend, Dr. Ethan Russo, Founder & CEO of CReDO Science. As, quite literally, one of the pioneering researchers in cannabis, and someone whose insights underpin much of the modern day understanding of the plant and the ECS, Ethan is truly a Rockstar guest for the pod. Over the episode we chat through, of course, what led him to the plant, his learnings from working with companies such as GW Pharmaceuticals, and the role that minor cannabinoids are playing in his current research projects at CReDO Science. www.professionallycannabispodcast.com
In this episode Amber Wise, PhD, joins the group discussion with Jahan Marcu, PhD, Nigam Arora, PhD, and Sara Jane Ward, PhD. We share our thoughts on federal agencies' views regarding hemp use in employees and contractors, trends in psychedelics and mental health, and cannabis proficiency testing (aka PT). As well as a story about what it is like to use psychedelic drugs as a participant in a clinical study. For our peer reviewed research articles we discuss recent data on the stability of mushroom biomass under different storage conditions and cannabis use for creativity in business ventures. Our game this week will test your knowledge about cannabis cultivation. Thank you to CReDO Science and Ethan Russo, MD for sponsoring this episode! https://credo-science.comEpisode's Group:Jahan Marcu, PhD (Moderator) Amber Wise, PhDSara Jane Ward, PhdNigam B. Arora, PhDNews Links: From the federal department of “Nice Try”! The DEA wants to know about your CBD and medical cannabis use pre-legalization (2:40)Vogue - New Frontier Report and Data: Could the embrace of psychedelics lead to a mental-health revolution? (9:30)What is it like to Smoke Salvia for Science (2nd article) (18:30)Cannabis Proficiency Testing ; Industry Imperative for Quality & Consumer Safety (33:04)Rapid Fire Science Study Links:Head in the clouds? Cannabis users' creativity in new venture ideation depends on their entrepreneurial passion and experience (For Discussion Puporses Only) (44:40)Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis (59:30)Today's Game (01:10:36): Test your cannabis cultivation trivia knowledge, with our new game called Room to Grow (01:10:36)Credits:Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition Music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting and naming this episode. More at: howtolaunchanindustry.com marcu-arora.com
In our 2021 premier episode we have a great conversation with renowned integrative physician, Dr. Dustin Sulak about easing symptoms of dementia, addressing chronic pain, and sleep issues with the same medicinal plant. You may know Dr. Sulak from his educational site Healer.com or from the many articles he's written, lectures he's given or panels he's participated in to help educate people worldwide on cannabis therapeutics. He's also a board member of the Society of Cannabis Clinicians and Americans for Safe Access. In upcoming episodes we connect with a Harvard Medical School professor. Having grown up in a home where his father was a very well known, ground-breaking cannabis researcher, and seeing how his older brother, who passed at 15, got relief from leukemia related nausea, vomiting and pain, Dr. Peter Grinspoon is considered an authority on all aspects of this healing herb, including adult and medicinal uses, as well as the racist misinformation, rather than science, that was the foundation of prohibition. He also knows first hand how powerful cannabis can be in healing from opioid addiction. PLUS! Dr. Bonni Goldstein, has treated thousands of adults and children and seen their quality of life improve with cannabis medicine. We'll talk about her book, “Cannabis is Medicine” and how her senior patients are finding relief from symptoms of dementia, chronic pain and getting better sleep. Dr. Babak Baban, is researching CBD and cannabinoids at the Dental College of Georgia at Augusta University. Some of his recently released studies include: one on how CBD helps reduce cytokine storms in COVID-19, which is really interesting, but the big news to us is about a mouse study where two weeks of high dose CBD seems to reset how proteins are made in Alzheimer's impacted mouse brains. We have an excellent panel discussion on How Cannabis Eases Anxiety and Depression among seniors with three geriatric specialists including President of the American Cannabis Nurses Association, Geriatric NP Eloise Theisen, RN, Geriatric Psychiatrist Dr. Phillip Grob, and Health services director of a world class assisted living facility and memory care in Santa Rosa. Dr. Blake Pearson, is a practicing family physician in Ontario, Canada treating hundreds of PLWD in facilities and at home. He's seen huge quality of life improvements in patients living with dementia using medical cannabis. Dr. Genester Wilson-King is a women's health expert. We'll talk about the impact of hormonal imbalances and risk for dementia and how cannabis may help. We're also going to connect with Dr. Ethan Russo about his comprehensive 2018 review article in Frontiers in Integrative Neuroscience, “Cannabis Therapeutics and the Future of Neurology” and do a deep dive into the Alzheimer's section as well as talk about other studies since then that question if cannabis helps dementia. Dr. Melanie Bone is the medical director of the cannabinoid initiative at an over-65 residential community in Florida with a teaching nursing home, memory care unit, hospice, and rehabilitation facility on site. We spoke with Dr. Bone in the 2020 season and look forward to connecting with her again and hearing how things are going! Dr. Patricia Frye, wrote one of the textbooks for the University of MD School of Pharmacy. We'll talk about the importance of healthcare provider education on cannabinoids and the endocannabinoid system and how cannabis may be helping seniors and people living with dementia. --- Send in a voice message: https://anchor.fm/cannabishelpsdementia/message Support this podcast: https://anchor.fm/cannabishelpsdementia/support
Founder and CEO of Credo Science Dr. Ethan Russo (also former Senior Medical Advisor at GW) shares his insights about the acquisition of GW Pharmaceuticals and discusses his experiences in cannabis drug development. Dr. Deb Kimless also joins the discussion to explore issues around psychedelics patents and the preservation of psychedelics producing fauna which ties into a book Dr. Russo authored 20 years ago about saving the rainforest (link below). Our scientific articles explore innovative cannabis research models and the safety of psychedelics in immunotherapy. At the end of the episode we put on our Good Manufacturing Practice hats, to play one of our favorite games. Episode's GroupJahan Marcu, PhDEthan Russo, MDNigam B. Arora, PhDDeb Kimless, MDDavid Vaillencourt, MScSarah Jane Ward, PhD (in spirit) News Links: COMPASS: We finally figured out how to make money off of hippie bean bags (3:14) https://www.vice.com/en/article/93wmxv/can-a-company-patent-the-basic-components-of-psychedelic-therapyJAZZ purchases GW for $7 Billion (11:40)https://ir.gwpharm.com/news-releases/news-release-details/jazz-pharmaceuticals-acquire-gw-pharmaceuticals-plc-creatingBeing Licked Out of Existence: Psychedelic Fauna Being Pushed to their Limits (29:20)https://www.forbes.com/sites/davidcarpenter/2021/02/02/psychedelic-toads-pushed-to-the-limit-conservationists-urge-synthetic-5-meo-dmt-option/?sh=17eeed8d9615Rapid Fire Science Study Links:Cannabis and Health Research: Rapid Progress Requires Innovative Research Design (42:17)https://pubmed.ncbi.nlm.nih.gov/31708066/ Is It Safe to Use Psychedelics During Cancer Immunotherapy? (58:49) https://www.biorxiv.org/content/10.1101/2021.02.01.429102v1 Bonus: Ethan Russo's Novel about Saving the Rainforesthttps://www.amazon.com/Last-Sorcerer-Echoes-Rainforest/dp/0789012707Today's Game (1:04:29):“Where's Vaillencourt?” a fun combination of Clue, Where's Waldo, and 20 Questions. Where we guess the location, type of facility, and type of product HLI cast member David Vaillencourt has done his most recent GMP assessment. (01:09:32) Credits:Podcast production by Joe Leonardo, Cover art by Ivan Artucovich, Intro music by Buddha by Kontekst, Transition and Outro Music by K. LOUK. Special thanks to Julian Amkraut for supporting this episode. More at: howtolaunchanindustry.com marcu-arora.com
Our guest today is Dr. Ethan Russo. Neurologist, psychopharmacology researcher and author. Dr. Russo is a true pioneer in the world of cannabinoid science, and remains one of the best resources for endocannabinoid and cannabinoid education on the planet. We covered some serious ground in this episode, including: - Dr. Russo's journey into Peru and the ancient Peruvian plant medicine he researched there. - The endocannabinoid system - Treatment resistant conditions and their relationship with clinical endocannabinoid deficiencies - What terpenes are, and the integral role they play in plant medicine Dr. Russo has an incredible mind and his passion for education rivals that of his passion for plant medicines. It was an absolute pleasure and honour to speak with him and I'm sure you'll gain as much from this episode as I did! Dr. Russo's current work can be found below: https://credo-science.com/ https://www.researchgate.net/profile/Ethan-Russo
A great conversation with one of the OG's in terms of cannabis as a medicine, Dr. Ethan Russo. We discuss CBD for Migraines, cannabis and neurogenesis, CBD for Diabetes of the brain (Alzheimer's), the role of terpenes and much more.
Nick talks to neurologist and plant medicine expert Dr. Ethan Russo about medical cannabis and related topics, such as cannabinoids (e.g. THC, CBD, CBG, THCV), terpenes (myrcene, limonene, beta-caryophyllene), endocannabinoid biology, and Ethan's thoughts on the legal cannabis industry, including whether the terms "Indica" and "Sativa" are meaningful.USEFUL LINKS:Download the podcast & follow Nick at his website[www.nickjikomes.com]Support the show on Patreon & get early access to episodes[https://www.patreon.com/nickjikomes]Sign up for the weekly Mind & Matter newsletter[http://eepurl.com/hFlc7H]Try MUD/WTR, a mushroom-based coffee alternative[https://www.mudwtr.com/mindmatter]Discount Code ($5 off) = MINDMATTEROrganize your digital highlights & notes w/ Readwise (2 months free w/ subscription)[https://readwise.io/nickjikomes/]Start your own podcast (get $20 Amazon gift card after signup)[https://www.buzzsprout.com/?referrer_id=1507198]Buy Mind & Matter T-Shirts[https://www.etsy.com/shop/OURMIND?ref=simple-shop-header-name&listing_id=1036758072§ion_id=34648633]Connect with Nick Jikomes on Twitter[https://twitter.com/trikomes]Learn more about our podcast sponsor, Dosist[https://dosist.com/]ABOUT Nick Jikomes:Nick is a neuroscientist and podcast host. He is currently Director of Science & Innovation at Leafly, a technology startup in the legal cannabis industry. He received a Ph.D. in Neuroscience from Harvard University and a B.S. in Genetics from the University of Wisconsin-Madison.Support the show (https://www.patreon.com/nickjikomes)
The cannabis that most people have access to isn't what it could be. A big part of that is a result of the way the plant has been bred to have high THC levels for the recreational market over the years."For the most part, around the world, we're still dealing with cannabis that is mostly high THC and high myrcene, which is gonna be very sedating, producing what we call colloquially couch lock, where the person feels immobilized," Dr. Ethan Russo explains on The Cannabis Enigma podcast. "So that might be fine for the person that's trying to get to sleep, but it's not at all good for the person that might need to work, or study, and function well in the process, and particularly for chronic pain conditions."Science has made great advances in identifying what chemical properties of a given cannabis chemovar would be beneficial for various diseases and treatments, "but that's a far cry from saying that they would be able to access a chemical variety of cannabis that would be appropriate for their treatment," Russo explains."We really haven't seen the capabilities of cannabis properly harnessed at this point," he adds.Dr. Russo, one of the premier cannabis researchers who is responsible for the theory of clinical endocannabinoid deficiency and has done a great deal of work on proving and harnessing the entourage effect, also discussed different approaches to dosing, and why developing a tolerance can actually be a good thing."The beauty of cannabis is, even though one gets accustomed to the psychoactive effects, the benefits on whatever you're treating remain. In other words, if we have a chronic pain patient and they get benefit from using cannabis, as long as that condition is stable — it's not getting worse — we don't see dose escalation over time, and in fact, there are many people, who have taken cannabis therapeutically for decades that are using the same dose."Dr. Russo will be speaking at the Whole Plant Expo.In the second part of the episode, Dustin McDonald of Americans for Safe Access interviews Sue Lewtin, a medical cannabis patient treating lyme disease, about her journey with the plant. Like so many others, Lewtin explains how her doctors got her started on the path of medical cannabis but that bulk of the work and learning had to be done on her own.Edited and mixed by Michael Schaeffer Omer-Man. Produced by Michael Schaeffer Omer-Man and Matan Weil. Music by Desca. The Cannabis Enigma podcast is a co-production of The Cannigma and Americans for Safe Access.
How has cannabis and the endocannabinoid system evolved over time? This week we welcome back the legendary Dr. Ethan Russo, one of the world's leading authorities on medical cannabis and botanical therapeutics, both as a physician and researcher. This episode, we discuss the origins and evolution of both the cannabis plant and the endocannabinoid system. We also look into how the biochemical diversity of cannabis has been altered by humans over time.View full show notes and summary here: https://www.cannabis-conversation.com/blogs/episode67About Dr. Ethan RussoEthan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and former Senior Medical Advisor to GW Pharmaceuticals. He served as study physician to GW Pharmaceuticals for three Phase III clinical trials of Sativex.He was a clinical neurologist in Missoula, Montana for 20 years in a practice with a strong chronic pain component. In 1995, he pursued a 3-month sabbatical doing ethnobotanical research with the Machiguenga people in Parque Nacional del Manu, Peru. He joined GW as a full-time consultant in 2003.He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, in Medicine at the University of Washington, and as visiting professor, Chinese Academy of Sciences.He is currently Past-President of the International Cannabinoid Research Society, and is former Chairman of the International Association for Cannabinoid Medicines.He is author of Handbook of Psychotropic Herbs, co-editor of Cannabis and Cannabinoids: Pharmacology, Toxicology and Therapeutic Potential, and author of The Last Sorcerer: Echoes of the Rainforest. He was founding editor of Journal of Cannabis Therapeutics, selections of which were published as books: Cannabis Therapeutics in HIV/AIDS, Women and Cannabis: Medicine, Science and Sociology, Cannabis: From Pariah to Prescription, and Handbook of Cannabis Therapeutics: From Bench to Bedside. He has also published numerous book chapters, and over thirty articles in neurology, pain management, cannabis, and ethnobotany. His research interests have included correlations of historical uses of cannabis to modern pharmacological mechanisms, phytopharmaceutical treatment of migraine and chronic pain, and phytocannabinoid-serotonergic and –vanilloid interactions.
What are terpenes and how important are they to the cannabis plant? This week we're joined by Dr. Ethan Russo, physician, researcher, and leading expert in the field of Medicinal Cannabis. In this episode, we discuss all things terpenoid, including how they are produced, varieties commonly found in cannabis, and their therapeutic benefits. Episode SummaryDr. Russo was classically trained as a neurologist, but turned back to a teenage interest in medicinal plants when he realised he was prescribing increasingly toxic drugs to his patients. In the early 90's he became interested in treating headaches and migraines, and took research trips to the Amazon rainforest in Peru to work with native tribes who treated the condition with botanicals.When he returned to the USA he knew that he wanted to change his career path, and became interested in the medicinal properties of essential oils, terpenes and terpenoids.Dr. Russo became interested in using cannabis medicinally and started the Journal of Cannabis Therapeutics. He quickly became an expert in the field, and worked as a consultant for GW Pharmaceuticals who had obtained a permit to grow cannabis for medicinal purposes in 1998.Later on he became a Senior Medical Advisor and was heavily involved with the development of Sativex and Epidiolex.The first cannabis derived pharmaceutical approved by the FDA was Epidiolex, which contains a 98% pure cannabidiol compound and is used to treat Lennox-Gastaut syndrome and Dravet syndrome.To get a drug approved by the FDA often requires between 10 and 12 years of research and between $700m and $1.2bn of expenditure.Dr. Russo has recently founded CReDO Science, who create innovative products and services related to cannabis and the endocannabinoid system, outside the realm of THC. Projects include over the counter treatments, novel extraction techniques, nutritional cannabis products, cannabis based disinfectant, and diagnostic tests. Terpenes are the aromatic components of plants which can be found in the leaves, bark, flowers and sometimes roots. They are used in aromatherapy which is the science of essential oils. An example of this is lemon oil, which denotes cleanliness and is a cleaning agent. The terpene responsible for this aroma is Limonene, which can be found in citrus fruits.Selective breeding for high THC strains means that many of the new strains have a dominant terpene of Myrcene, which interacts with THC to produce sedative effects.Dr. Russo is currently conducting a piece of research which looks into the effects of using THC with differing terpenoids, using memory tests as a measure.There are over 20,000 identified terpenoids, none of which (so far) are unique to cannabis. Alpha Pinene and Limonene are the most abundant in nature but are not found in cannabis very often. In cannabis, Myrcene and Caryophyllene are often found, which interact with CB2 receptors. Caryophyllene is both a terpene and a cannabinoid.In any cannabis sample, there are on average 3-5 prominent terpenoids along with trace amounts of many more.Terpenes act as a defence mechanism for plants, their strong smells either promote pollination, deter predation by insects or to prevent grazing by mammals. Cannabinoids and Terpenoids are both produced in Capitate Glandular Trichomes which are most abundant in unfertilised female plants. Many terpenes have pain reducing effects which work through distinct mechanisms. Quotables‘Terpenes are critical components to the medicinal effects of cannabis' 04:20‘Essential oils are extremely potent, so the amounts involved are tiny' 22:25
We were once carefree below-the-line film and TV workers: I did props and set dressing and Dave was an Assistant Director and occasional actor. Then we were thrust into family caregiving when my mom was suddenly diagnosed with Alzheimer's Disease. We learned so much from my mother's decade-long journey that I felt we had to share our best practices with other families in crisis. We created AlzNotes.com to provide care gap training and plant based education to others in relationship with dementia. My mom transitioned to Pure Positive Energy in 2019. Cannabis Helps Dementia podcast was born out of my desire to shout from the rooftops how we and others have eased the suffering of loved ones living with dementia by using a medicinal herb where there is no other relief available. You'll hear the science and stories of how cannabis helps ease the difficult behavioral symptoms caused by dementing illnesses. One of the things we learned on this life-changing journey was that the United States Department of Health has held a patent since 1998 specifically for neuroprotection which inspired us to do more research. Patent # 6630507B1 “...cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia…” When we started to get serious about this research, we learned about Dr. Ethan Russo, who is a world renowned neurologist, psychopharmacology researcher, former Senior Medical Advisor to GW Pharmaceuticals (GW created Epidiolex and Sativex, cannabis based medications for epilepsy and MS symptoms) and he is a member of the Society of Cannabis Clinicians. Dr. Russo is a badass rockstar of medical cannabis research and among many other things, he wrote a review article in Frontiers in Integrative Neuroscience, “Cannabis Therapeutics and the Future of Neurology” that really got my attention. Dr. Russo gives the reader an introduction to cannabis medicine, then shows us the studies that have already been done that show how cannabis helps multiple neurological issues including epilepsy, brain tumors, traumatic brain injury, Parkinson's Disease and of course, Alzheimer's. We hope you like EP1 with Dr. Russo. Please share, subscribe, rate and review to learn more about how cannabis helps dementia. In Solidarity, Chela THANK YOU! Dr. Ethan Russo , Anchor.fm , Society of Cannabis Clinicians , “The Scientist” Documentary Opening music “Wishful Thinking” by Dan Lebowitz; montage music “Cartoon Bank Heist” by Doug Maxwell Media Right Productions ...and thank you Mom, my greatest teacher. More reading: Project CBD , “World Health Organization Recommends Reclassifying Marijuana Under International Treaties” Forbes 2/1/2019 article [Full description including glossary coming to CHD website] --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/cannabishelpsdementia/message Support this podcast: https://anchor.fm/cannabishelpsdementia/support
We are excited to announce CannMed 2020's Keynote Presenter in the Science Focus Area is Dr. Ethan Russo. The title of Dr. Russo's presentation is “Cannabis and Psychiatry: The Final Frontier”, and it will explore basic science and clinical trial data to assess the role of cannabis psychopharmacology with respect to issues of impairment, depression, insomnia, PTSD, schizophrenia, anxiety and addiction. You can hear about this fascinating topic and more in our latest episode of the CannMed Coffee Talk Podcast, where Dr. Russo joins us as a guest. This is a great episode for listeners who are new to cannabis medicine because Dr. Russo covers some of the basics, like "what is the endocannabinoid system?" Having said that, there is still plenty of meat on the bone for more advanced listeners. Use the player at the bottom at the post to listen. Dr. Russo began his career as a physician, board-certified in Neurology with a Special Qualification in Child Neurology, but he has always held a strong interest in medicinal plants, which he gradually incorporated into his practice and research endeavors, with the intention of bringing cannabis-based and other botanical agents back into the mainstream of medicine. He is a graduate of the University of Pennsylvania (Psychology) and the University of Massachusetts Medical School, before residencies in Pediatrics in Phoenix, Arizona and in Child/Adult Neurology at the University of Washington, and was a clinical neurologist in Missoula, Montana for 20 years. After his clinical experience, he began dedicating his career to developing innovative approaches targeting the human endocannabinoid system to produce dramatic results for patients suffering from a range of neuro- and immuno-based diseases and disorders. From 2003 to 2014, Dr. Russo was instrumental in developing both Sativex® for pain and MS, and Epidiolex® for intractable epilepsy while at GW Pharmaceuticals. In 2015, he became Medical Director of PHYTECS, a company devoted to the research and development of medicines, supplements and lifestyle approaches to optimizing the function of the endocannabinoid system (ECS), the critical homeostatic regulatory mechanism of human physiology. From 2015-2017, he was Director of Research and Development for the International Cannabis and Cannabinoids Institute. Dr. Russo has also held faculty appointments in Pharmaceutical Sciences at the University of Montana, in Medicine at the University of Washington, and as visiting professor, the Chinese Academy of Sciences. He is a Past-President of the International Cannabinoid Research Society, and former Chairman of the International Association for Cannabinoid Medicines. He serves on the Scientific Advisory Board for the American Botanical Council and has published several books, numerous book chapters, and over forty articles in neurology, pain management, cannabis, and ethnobotany, and he has consulted or lectured on these topics in more than 30 US states and 30 countries. His current venture, called CReDO Science, aims to advance cannabis-based and botanical therapeutics via the development of optimized chemovars and extracts, as well as pursuing novel formulations and diagnostics related to the endocannabinoid system. More information can be found by visiting https://credo-science.com. Needless to say, we are delighted to have him as such an important part of CannMed 2020. SIGN UP FOR PODCAST UPDATES AND ENTER TO WIN 2 VIP DINNER TICKETS! Related Links: Ethan Russo, MD CannMed 2018 PresentationEthan Russo, MD ResearchGate ProfileCReDO Science LLC Website
Dr. Ethan Russo is a well-known name in cannabis research. He has been studying the plant since around 1996 and coined the tern "Endocannabinoid Deficiency". We covered a TON in this episode, Some topics include: What is the Endocannabinoid System What is Endocannabinoid Deficiency How to Use Cannabis to Solve Endocannabinoid Deficiency Cannabis and The Opioid Epidemic Cannabis for Cancer, Alzheimer's, and other Diseases Topicals, do They Work? Industry Predictions Read all that and more on our blog here >>>
Kirk and Trevor discuss PTSD with Dr. Mike Hart founder of ReadyToGo Clinic. Dr. Hart talks about how PTSD, migraines, IBS and some other conditions are due at least in part to an endocannabinoid deficiency. That means cannabis is an obvious treatment for PTSD. Also hear how cannabis can also be used in sports medicine and about Kirk's Runners' High on the Columbia Ice Fields. Music by: Bif Naked - Santa Claus is Comin to Town - https://www.youtube.com/watch?v=h8zb5VVydpA - http://www.bifnaked.com/home.html (Yes we got a SOCAN membership to use this song all legal and proper like) Additional Music: Desiree Dorion www.desireedorion.com/ Marc Clement http://marcclementmusic.com/ Links: Dr. Mike Hart's Joe Rogan Interview (Episode 1246): https://www.youtube.com/watch?v=YHwSmwEwmV4&t=38s Scientific American "The Case of a Woman Who Feels Almost No Pain Leads Scientists to a New Gene Mutation" - March 30/19 - Jacquelyn Corley - https://www.scientificamerican.com/article/the-case-of-a-woman-who-feels-almost-no-pain-leads-scientists-to-a-new-gene-mutation/ Readytogo Clinic - https://mikehartmd.com/ Mike Hart Book - Friendly Fire: Why Vets Are Ditching Pills and Lighting Up to Treat PTSD - https://www.amazon.ca/Friendly-Fire-Ditching-Pills-Lighting-ebook/dp/B079KY46WG/ref=sr_1_1?keywords=mike+hart+cannabis+ptsd&qid=1576791702&sr=8-1 Benzodiazepines for PTSD: A Systemic Review and Meta-Analysis. Guina et al. Journal of Psychiatric Practice. July 2015 - https://www.ncbi.nlm.nih.gov/pubmed/26164054 Reductions in Circulating Endocannabinoid Levels in Individuals with Post-Traumatic Stress Disorder Following Exposure to the World Trade Center Attacks. Matthew N. Hill et al. Psychoneuroendocrinology. Sept 2013. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870889/ Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes. Ethan Russo. Cannabis and Cannabinoid Research. July 2016. https://www.ncbi.nlm.nih.gov/pubmed/28861491
Kirk and Trevor discuss PTSD with Dr. Mike Hart founder of ReadyToGo Clinic. Dr. Hart talks about how PTSD, migraines, IBS and some other conditions are due at least in part to an endocannabinoid deficiency. That means cannabis is an obvious treatment for PTSD. Also hear how cannabis can also be used in sports medicine and about Kirk's Runners' High on the Columbia Ice Fields. Music by: Bif Naked - Santa Claus is Comin to Town - https://www.youtube.com/watch?v=h8zb5VVydpA - http://www.bifnaked.com/home.html (Yes we got a SOCAN membership to use this song all legal and proper like) Additional Music: Desiree Dorion www.desireedorion.com/ Marc Clement http://marcclementmusic.com/ Links: Dr. Mike Hart's Joe Rogan Interview (Episode 1246): https://www.youtube.com/watch?v=YHwSmwEwmV4&t=38s Scientific American "The Case of a Woman Who Feels Almost No Pain Leads Scientists to a New Gene Mutation" - March 30/19 - Jacquelyn Corley - https://www.scientificamerican.com/article/the-case-of-a-woman-who-feels-almost-no-pain-leads-scientists-to-a-new-gene-mutation/ Readytogo Clinic - https://mikehartmd.com/ Mike Hart Book - Friendly Fire: Why Vets Are Ditching Pills and Lighting Up to Treat PTSD - https://www.amazon.ca/Friendly-Fire-Ditching-Pills-Lighting-ebook/dp/B079KY46WG/ref=sr_1_1?keywords=mike+hart+cannabis+ptsd&qid=1576791702&sr=8-1 Benzodiazepines for PTSD: A Systemic Review and Meta-Analysis. Guina et al. Journal of Psychiatric Practice. July 2015 - https://www.ncbi.nlm.nih.gov/pubmed/26164054 Reductions in Circulating Endocannabinoid Levels in Individuals with Post-Traumatic Stress Disorder Following Exposure to the World Trade Center Attacks. Matthew N. Hill et al. Psychoneuroendocrinology. Sept 2013. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870889/ Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes. Ethan Russo. Cannabis and Cannabinoid Research. July 2016. https://www.ncbi.nlm.nih.gov/pubmed/28861491
Gold in the archives, we re-play a splendid conversational cavort with Dr. Ethan Russo and grand to hear him speak such wild ideas of CBD benefits in 2008 which still pushes may to Buy CBD Products online today from kushiebites.com. December 4, 2008 Show Researchers find oldest-ever stash! Caroline welcomes Dr. Ethan Russo, neurologist, entheogenic scientist lead author for the research team that discovered oldest stash ever—2700 year old marijuana placed in shaman's grave in China, “the oldest documentation of cannabis as a pharmacologically active agent” Support The Visionary Activist Show on Patreon for weekly Chart & Themes ($4/month) and more… *Woof*Woof*Wanna*Play?!?* The post The Visionary Activist Show – Sacramental Stash Radio appeared first on KPFA.
Ben Cassiday is a cannabis educator and business owner focused on building tools for productdevelopers and other educators. He is a founding partner of the GreenWay Cannabis Network – anationwide cannabis health care clinic system and True Terpenes – a terpene education and supply company. Aside from cannabis, Ben is passionate about the health benefits of a plant-baseddiet and supports harm reduction programs.In this weeks podcast Ben talks about the importance of terpenes and their new found fame due to the cannabis movement. We ask will the interest in less know cannanoids like CBG CBB we over shadowed by interest in terpenes. We learn about the terpene superclass theory and Phillip Henry's Hyperclasses theory and he shed light into new research on myrcene as a skin penetratorVisit Ben's website for more information on Terpenes https://trueterpenes.com or his work at http://greenwaymarijuana.com/https://trueterpenes.com/Publications by Ben https://hightimes.com/sponsored/hunting-for-terpenes-with-true-terpenes/ If you are interested in any of the papers, book or podcast Ben mentioned :Cannabis chemovar classification: terpenes hyper-classes and targeted genetic markers for accurate discrimination of flavours and effects by Philippe Henry https://peerj.com/preprints/3307/ Dr. Ethan Russo : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165946/https://www.researchgate.net/publication/317354478_Cannabis_Pharmacology_The_Usual_Suspects_and_a_Few_Promising_LeadsBook Clinical Aromatherapy: Essential Oils in Healthcare https://www.amazon.com/Clinical-Aromatherapy-Essential-Oils-Healthcare/dp/0702054402Shaping Fire Podcast :https://www.shapingfire.com/To learn more about plants & your health from Colleen at LabAroma check out this informative PDF: https://mailchi.mp/2fe0e426b244/osw1lg2dkh
Dr .Ethan Russo, is a board-certified neurologist, psychopharmacology researcher, and the director of the Institute For Cannabis and Cannabinoid Research. He is a former Senior Medical Advisor to GW Pharmaceuticals, a biotechnology company that specializes in developing different ways of targeting the endocannabinoid system for therapeutic benefit.He is currently on the board of Director of the International Cannabinoid Research Society, and is former Chairman of the International Association for Cannabinoid Medicines. Widely published author in many scientific journals, and contributor and editor of several booksDo we really how much about the endocannabinoid system (ECS) at all and do the terpenes in cannabis matter? We ask Dr Russo just that and more in this episode. We discuss how without clinical research to support the cannabis movement we don't have a foundation for the future of this plant medically. The cannabis prohibition greatly affected the development of this much needed research but with new evidence emerging supporting the Entourage effect we talk through what this mean for us today. https://www.phytecs.com/wp-content/uploads/2015/02/IntroductionECS.pdf https://www.amazon.com/Cannabis-Pariah-Prescription-Ethan-Russo/dp/0789023997 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165946/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334252/ http://www.phytecs.com/team/erusso/ To learn more about plants & your health from Colleen at LabAroma check out this informative PDF: https://mailchi.mp/2fe0e426b244/osw1lg2dkhDisclaimer: The information presented in this podcast is for educational purposes only, and is not intented to replace professional medical advice. Please consult your doctor if you are in need of medical care, and before making any changes to your health routine.
Ethan is internationally renowned for his research on cannabis compounds and their roles in the body. As a neurologist and psychopharmacologist, Ethan has established himself as a pioneer and thought leader regarding the integral role plant-based medicine should play in modern therapeutics. In this episode we discuss current cannabis research, the endocannabinoid system, the future potential of medical cannabis, cannabis as a gateway drug and much more. Not one to be missed!
Did Hart miss his calling as a rapper? Find out on this week's Strain vs. Strain. Also on this episode, Dr. Ethan Russo, Herbalizer, and we answer your questions about medical cannabis.
In this week's podcast episode, Dr. Ethan Russo — one of our earliest and most esteemed guests — returns to the show to discuss his latest article, “Beyond Cannabis: Plants and the Endocannabinoid System.” Dr. Russo is a neurologist and psychopharmacology researcher, and is the former Senior Medical Advisor for GW Pharmaceuticals. He worked as a clinical neurologist in Missoula, Montana for 20 years, where much of his practice focused on the treatment of chronic pain. Today, Dr. Russo is one of the world's leading researchers in the field of cannabis terpenes and the endocannabinoid system. He has authored several books about cannabis, cannabinoids, pharmacology, and rare botanicals, and he has published over 30 articles covering neurology, pain management, cannabis, and ethno-botany. In this interview, Dr. Russo and Ganjapreneur podcast host Shango Los discuss how various foods — including black pepper, kava, the common carrot, and more — can actually help balance the cannabinoid levels in your body. For a full transcript: https://www.ganjapreneur.com/ethan-russo-endocannabinoid-nutrition/
When the acceptance of medical cannabis goes mainstream, the pharmaceuticals landscape will face the most significant disruption of its existence. Due to the federal classification of marijuana as a Schedule 1 controlled substance, researching possible medical uses for the plant has been difficult. However, this has not stopped some companies from conducting their own research and clinical trials of cannabis medicines. Our latest podcast interview features Dr. Ethan Russo, formerly Senior Medical Advisor to GW Pharmaceuticals, who participated in three clinical trials of the drug Sativex. Dr. Russo recently left GW Pharmaceuticals and can now speak publicly for the first time about his research: up until now, he could only be heard at expensive, exclusive conferences. He is now Medical Director at Phytecs, a company specializing in the production of cannabis-based treatments related to the endocannabinoid system. Everything that contemporary cannabis healers talk about in relation to cannabis as medicine is based on Dr. Russo's published research, including the power of cannabis terpenes, the Entourage Effect, and Endocannabinoid Deficiency. In this interview, our host Shango Los asks Dr. Russo about Endocannabinoid Deficiency (ECD) and the potential for it to be treated by cannabis. All human beings have an endocannabinoid system, which, according to Russo, regulates nearly every aspect of physiology. Endocannabinoid Deficiency is just coming into general awareness now as a cause behind several conditions including Migraines, Fibromyalgia, Irritable Bowel Syndrome, Phantom Limb Pain, Infantile colic, Glaucoma, PTSD, Bipolar disease and others. If cannabis becomes accepted by the mainstream medical community as a treatment for ECD and its associated conditions, the implications for the pharmaceuticals market would be staggering to say the least. Listen to the podcast or read the transcript below to learn about the science behind ECD and how cannabis can be used as a treatment. For a full transcript: https://www.ganjapreneur.com/ethan-russo-endocannabinoid-deficiency-medical-cannabis/
We spoke with US-based neurologist Ethan Russo MD, Director of Research and Development at the International Cannabis and Cannabinoids Institute, at the 2019 IACM Cannabinoids in Medicine conference in Berlin, Germany. Dr. Russo outlined challenges for conducting clinical trials of cannabis for the various medical conditions that are already supported by subtantial evidence warranting further studies. He explained the problem of getting funding and approvals for clinical trials. Dr Russo described the impact of increased placebo-responses over the past decades, and that subjects may see through blinding if they feel intoxicated, but notes the existence of a sweet-spot where symptoms can be treated without intoxication. The argument that cannabis use may increase the likelihood of triggering psychosis or schizophrenia in patients is also addressed. Dr Russo said the incidence of schizophrenia in society had dropped despite a significant increase in recreational cannabis use. He also notes that there is no impairment in patients using normal doses and that cannabinoid medicines can be prepared that do not intoxicate, but that precautions should be taken. Dr Russo points out that in two recent Phase II clinical trials CBD has been shown to treat schizophrenia with far fewer side effects than traditional antipsychotic medicines.
Napro Research with Mark Lewis today on Grassroots Marketing with Jorge Hermida only on Cannabis Radio. In partnership with Biotech Institute, his work focused on the targeted breeding of cannabis cultivars with proven therapeutic properties. Together, Napro Research and Biotech Institute have created patented and award-winning chemovars. Mark also co-authored “Pharmacological Foundations of Cannabis Chemovars” with Dr. Ethan Russo that serves as a critical foundation for further research. The need to look at cannabis beyond THC. There are over a hundred cannabinoids and at least 150 terpenes packed into the species. With so much potential beyond extreme intoxication, it's time to open up the genome and disrupt the market obsession with THC. Targeting breeding now allows for controlled whole-plant cannabis research in a way that was never before possible.