Podcasts about kloser

During a very difficult time in her life, Christine initially felt crushed, so she went on a deep inquiry.  She followed the inspiration that came, chose to pursue what she was inspired to do and put her family and business back on track.  She shares the following nuggets of life wisdom: - determine who you are inside - seek a sense of self that's not tied to external sense of success - dig deep to see the grace - something good can come out of this - look for the good in the challenge - take a breath and trust https://christinekloser.com  tags:  Christine, Kloser, writer, author, speaker, entrepreneur, transform, your, life, story, stories, that, empower, empowering, empowerment, inspire, inspiring, inspiration, encourage, encouraging, encouragement, hope, light, podcast, Sean, https://storiesthatempower.com 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.15.516580v1?rss=1 Authors: Mullen, M. T., Goff, A., Billings, J., Kloser, H., Huard, C., Mitchell, J., Hambright, W. S., Ravuri, S., Huard, J. Abstract: Mesenchymal stem cells (MSCs) have long been viewed as a promising therapeutic for musculoskeletal repair. However, regulatory concerns including tumorgenicity, inconsistencies in preparation techniques, donor-to-donor variability, and the accumulation of senescence during culture expansion have hindered the clinical application of MSCs. Senescence, in particular, is a driving mechanism for MSC dysfunction with advancing age. Often characterized by increased reactive oxygen species, senescence-associated heterochromatin foci, inflammatory cytokine and chemokine secretion, and reduced proliferative capacity, senescence directly inhibits MSCs efficacy as a therapeutic for musculoskeletal regeneration and repair. Furthermore, autologous delivery of senescent MSCs can further induce disease and aging progression through the secretion of the senescence-associated secretory phenotype (SASP) and mitigate the regenerative potentetial of MSCs. To combat these issues, the use of senolytic agents to selectively clear senescent cell populations has become popular. However, their benefits to human MSCs during the culture expansion process have not yet been elucidated. To address this, analyzed markers of senescence during culturing of human primary adipose-derived stem cells (ADSCs), a population of fat-resident MSCs commonly used in regenerative medicine applications. Next, we used the senolytic agent fisetin to determine if we can reduce these markers of senescence within our culture-expanded ADSC populations. Our results indicate that ADSCs acquire common markers of cellular senescence including increased reactive oxygen species, senescence-associated {beta}-galactosidase, and senescence-associated heterochromatin foci. Furthermore, we found that the senolytic agent fisetin works in a dose-dependent manner and selectively attenuates these markers of senescence while maintaining the differentiation potential of the expanded ADSCs. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

From banter, bits, and doing it all for the music and the fans, to the animating power of STEM education as a force for good in the world Dr. Matt Kloser, founding director of the Center for STEM Education, shares how “The Story of Science” is an unfinished narrative we can all help write, as well as, S'more Than Coffee playing tennis with John McEnroe, and closing out the show on keyboards with Bruce Springsteen.

Muziek van Thomas Wander en Harald Kloser bij de rampenfilm Moonfall, van Roland Emmerich (die we kennen van Independence Day en The Day After Tomorrow). De maan komt in botsing met iets mysterieus waardoor een botsing tussen maan en aarde onafwendbaar lijkt - tenzij een ruimtemissie slaagt. Nogal onwaarschijnlijk allemaal, maar de muziek is beslist goed en vakkundig gemaakt. Schatplichtig aan grootmeester John Williams, maar dat is geen schande. De componisten van de muziek bij Moonfall komen uit Oostenrijk, Thomas Wander is er geboren in 1973 en hoewel hij eigelijk jazzpianist wilde worden werd hij op een zeker moment gegrepen door de emotionele kracht van filmmuziek, dus vertrok hij nog voor z'n 20e naar Los Angeles om daar filmcompositie te studeren. Hij won inmiddels een paar mooie prijzen, en schreef muziek voor bijvoorbeeld 10.000 BC, White House Down, Independence Day Resurgence en nu dus Moonfall. Wander werkt vaak samen met een andere Oostenrijkse componist, ook in dit geval weer, namelijk Harald Kloser, geboren in 1956 en niet alleen componist maar ook scriptschrijver en producer. Kloser is medeveratnwoordelijk geweest voor de muziek bij The Day After Tomorrow, en maakte ook bijvoorbeeld de muziek bij Alien vs. Predator. En nu dus Wander en Kloser, de muziek voor Moonfall.

We've got a very important issue to talk about this week. Apple wants to look at your private pictures. They've made such a big deal about privacy for years, so what's changed and why can't we trust them anymore? What have you done Tim Apple?The Australian government really hasn't liked supporting the games industry, despite years of lobbying and studies into how great the industry is for the economy. Someone's finally got through to them and we'll be getting changes to tax and visas to help encourage AAA development.Jason Mamoa thinks superheroes are like Greek mythology. Turns out the only reason he's joining the Scorsese comic genre battle is to remind everyone he wants to talk about climate change in his movies. Anyway, we all know his best role will be Duncan Idaho in Dune. It better not get delayed againApple's controversial new child protection features- https://www.theverge.com/2021/8/10/22613225/apple-csam-scanning-messages-child-safety-features-privacy-controversy-explained- https://www.ask-solutions.org/blog/2021/08-11-01?fbclid=IwAR1M731S3OrleR84O6134H-ZWXb5EtBoTY9tyXlIs0TiUXBVFwgHpP8Qmvc- https://www.reuters.com/technology/exclusive-apples-child-protection-features-spark-concern-within-its-own-ranks-2021-08-12/Australian Games Industry gets a Government Injection- https://www.gamesindustry.biz/articles/2021-08-10-how-australia-is-creating-a-sustainable-video-game-development-ecosystem?Jason Mamoa's take on superhero movies- https://boundingintocomics.com/2021/08/09/aquaman-star-jason-momoa-defends-superhero-movies-as-an-art-form-in-response-martin-scorseses-genre-criticisms/Other topics discussedWorst Cooks in America (an American reality television series that premiered on January 3, 2010, on Food Network. The show takes 12 to 16 contestants (referred to as "recruits") with very poor cooking skills through a culinary boot camp, to earn a cash prize of $25,000 and a Food Network cooking set.)- https://en.wikipedia.org/wiki/Worst_Cooks_in_AmericaFBI–Apple encryption dispute (The FBI–Apple encryption dispute concerns whether and to what extent courts in the United States can compel manufacturers to assist in unlocking cell phones whose data are cryptographically protected. There is much debate over public access to strong encryption. The Federal Bureau of Investigation (FBI) wanted Apple to create and electronically sign new software that would enable the FBI to unlock a work-issued iPhone 5C it recovered from one of the shooters who, in a December 2015 terrorist attack in San Bernardino, California, killed 14 people and injured 22.)- https://en.wikipedia.org/wiki/FBI%E2%80%93Apple_encryption_disputeHow Does the YouTube Algorithm Work in 2021? The Complete Guide- https://blog.hootsuite.com/how-the-youtube-algorithm-works/Perceptual hashing (the use of an algorithm that produces a snippet or fingerprint of various forms of multimedia. A perceptual hash is a type of locality-sensitive hash, which is analogous if features of the multimedia are similar.)- https://en.wikipedia.org/wiki/Perceptual_hashingreCAPTCHA (a CAPTCHA system that enables web hosts to distinguish between human and automated access to websites. The original version asked users to decipher hard to read text or match images. Version 2 also asked users to decipher text or match images if the analysis of cookies and canvas rendering suggested the page was being downloaded automatically. reCAPTCHA is owned by Google.)- https://en.wikipedia.org/wiki/ReCAPTCHAThe Shadow Brokers (a hacker group who first appeared in the summer of 2016. They published several leaks containing hacking tools, including several zero-day exploits, from the "Equation Group" who are widely suspected to be a branch of the National Security Agency (NSA) of the United States.)- https://en.wikipedia.org/wiki/The_Shadow_BrokersElectronic Frontier Foundation (The Electronic Frontier Foundation (EFF) is an international non-profit digital rights group based in San Francisco, California. The foundation was formed on 10 July 1990 by John Gilmore, John Perry Barlow and Mitch Kapor to promote Internet civil liberties.)- https://en.wikipedia.org/wiki/Electronic_Frontier_Foundation- https://www.eff.org/WarGames (a 1983 American Cold War science fiction techno-thriller film written by Lawrence Lasker and Walter F. Parkes and directed by John Badham. The film, which stars Matthew Broderick, Dabney Coleman, John Wood, and Ally Sheedy, follows David Lightman (Broderick), a young hacker who unwittingly accesses a United States military supercomputer programmed to predict and execute nuclear war against the Soviet Union.)- https://en.wikipedia.org/wiki/WarGamesHackers (a 1995 American crime film directed by Iain Softley and starring Jonny Lee Miller, Angelina Jolie, Jesse Bradford, Matthew Lillard, Laurence Mason, Renoly Santiago, Lorraine Bracco, and Fisher Stevens. The film follows a group of high school hackers and their involvement in a corporate extortion conspiracy.)- https://en.wikipedia.org/wiki/Hackers_(film)Shodan (Shodan is the world's first search engine for Internet-connected devices. Discover how Internet intelligence can help you make better decisions.)- https://www.shodan.io/PhotoDNA (PhotoDNA creates a unique digital signature (known as a “hash”) of an image which is then compared against signatures (hashes) of other photos to find copies of the same image. When matched with a database containing hashes of previously identified illegal images, PhotoDNA is an incredible tool to help detect, disrupt and report the distribution of child exploitation material. PhotoDNA is not facial recognition software and cannot be used to identify a person or object in an image. A PhotoDNA hash is not reversible, and therefore cannot be used to recreate an image.)- https://www.microsoft.com/en-us/photodnaThe Trauma Floor The secret lives of Facebook moderators in America- https://www.theverge.com/2019/2/25/18229714/cognizant-facebook-content-moderator-interviews-trauma-working-conditions-arizonaMortal Kombat 11 Developer Was Diagnosed with PTSD Due to Graphic Violence- https://segmentnext.com/mortal-kombat-11-developer-ptsd/Facebook will pay $52 million in settlement with moderators who developed PTSD on the job- https://www.theverge.com/2020/5/12/21255870/facebook-content-moderator-settlement-scola-ptsd-mental-healthArtificial neural network (usually simply called neural networks (NNs), are computing systems inspired by the biological neural networks that constitute animal brains. An ANN is based on a collection of connected units or nodes called artificial neurons, which loosely model the neurons in a biological brain.)- https://en.wikipedia.org/wiki/Artificial_neural_networkBob's Burgers – The Snake Song- https://genius.com/Bobs-burgers-the-snake-song-lyrics- https://www.youtube.com/watch?v=-tvhw7jnYi0Financial crisis of 2007–2008 (also known as the global financial crisis (GFC), was a severe worldwide economic crisis. Prior to the COVID-19 recession in 2020, it was considered by many economists to have been the most serious financial crisis since the Great Depression.)- https://en.wikipedia.org/wiki/Financial_crisis_of_2007%E2%80%932008Halfbrick Studios (Australian video game developer based in Brisbane. The company primarily worked on licensed games until 2008. The company released Fruit Ninja (2010) and Jetpack Joyride (2011).)- https://en.wikipedia.org/wiki/Halfbrick_StudiosUntitled Goose Game (a 2019 puzzle stealth game developed by House House and published by Panic. Players control a goose who bothers the inhabitants of an English village. The player must use the goose's abilities to manipulate objects and non-player characters to complete objectives. It was released for Microsoft Windows, macOS, Nintendo Switch, PlayStation 4, and Xbox One.)- https://en.wikipedia.org/wiki/Untitled_Goose_GameFruit Ninja (a video game developed by Halfbrick. It was released April 21, 2010 for iPod Touch and iPhone devices, July 12, 2010 for the iPad, September 17, 2010 for Android OS devices.)- https://en.wikipedia.org/wiki/Fruit_NinjaFiverr (Israeli online marketplace for freelance services. The company provides a platform for freelancers to offer services to customers worldwide.)- https://en.wikipedia.org/wiki/FiverrActivision Blizzard Lawsuit Alleges Horrific Mistreatment Of Women- https://www.forbes.com/sites/paultassi/2021/07/22/activision-blizzard-lawsuit-alleges-horrific-mistreatment-of-women/?sh=56144afb166cYongYea - Scummy Amazon Policy That Steals Employees' Personal Game Projects Dropped After Backlash From Devs- https://www.youtube.com/watch?v=oQtKfutVFTIMotion Picture Production Code (a set of industry guidelines for the self-censorship of content that was applied to most United States motion pictures released by major studios from 1934 to 1968. It is also popularly known as the Hays Code, after Will H. Hays, who was the president of the Motion Picture Producers and Distributors of America (MPPDA) from 1922 to 1945.)- https://en.wikipedia.org/wiki/Motion_Picture_Production_CodeBreaking Bad (an American neo-Western crime drama television series created and produced by Vince Gilligan. The show aired on AMC from January 20, 2008, to September 29, 2013, consisting of five seasons for a total of 62 episodes.)- https://en.wikipedia.org/wiki/Breaking_Bad‘Simpsons' Episode Featuring Michael Jackson Kept Off Disney+- https://www.hollywoodreporter.com/tv/tv-news/simpsons-episode-featuring-michael-jackson-kept-disney-1254609/2012 (a 2009 American science fiction disaster film directed and written by Roland Emmerich. It was produced by Harald Kloser, Mark Gordon, and Larry J. Franco, and written by Kloser and Emmerich. The film stars John Cusack, Amanda Peet, Chiwetel Ejiofor, Oliver Platt, Thandiwe Newton, Danny Glover, and Woody Harrelson.)- https://en.wikipedia.org/wiki/2012_(film)Geostorm (a 2017 American science fiction disaster film directed, co-written, and co-produced by Dean Devlin (in his feature directorial debut). The film stars Gerard Butler, Jim Sturgess, Abbie Cornish, Ed Harris, and Andy García. It follows a satellite designer who tries to save the world from a storm of epic proportions caused by malfunctioning climate-controlling satellites.)- https://en.wikipedia.org/wiki/GeostormVolcano (a 1997 American disaster film directed by Mick Jackson, and produced by Andrew Z. Davis, Neal H. Moritz and Lauren Shuler Donner. The storyline was conceived from a screenplay written by Jerome Armstrong and Billy Ray, and is inspired by the 1943 formation of the Parícutin volcano in Paricutin, Mexico.)- https://en.wikipedia.org/wiki/Volcano_(1997_film)Thanos (a genocidal warlord from Titan, whose own main objective was to bring stability to the universe by wiping out half of all life at every level, as he believed its massive population would inevitably use up the universe's entire supply of resources and condemn this. To complete this goal, Thanos set about hunting down all the Infinity Stones, being confident that the combined power of the Stones would achieve his goal.)- https://marvelcinematicuniverse.fandom.com/wiki/ThanosNo Man's Sky Gameplay Trailer | E3 2014 | PS4- https://www.youtube.com/watch?v=nLtmEjqzg7MAngryJoeShow - No Man's Sky Angry Review- https://www.youtube.com/watch?v=uTTPlqK8AnY&t=1897sInternet Historian - The Engoodening of No Man's Sky- https://www.youtube.com/watch?v=O5BJVO3PDeQ&t=59sAgent Orange (a herbicide and defoliant chemical, one of the "tactical use" Rainbow Herbicides. It is widely known for its use by the U.S. military as part of its herbicidal warfare program, Operation Ranch Hand,during the Vietnam War from 1961 to 1971. It is a mixture of equal parts of two herbicides, 2,4,5-T and 2,4-D. In addition to its damaging environmental effects, traces of dioxin (mainly TCDD, the most toxic of its type) found in the mixture have caused major health problems for many individuals who were exposed, and their offspring. )- https://en.wikipedia.org/wiki/Agent_OrangeThe Tramp (also known as The Little Tramp, was British actor, Charlie Chaplin's most memorable on-screen character and an icon in world cinema during the era of silent film. The Tramp is also the title of a silent film starring Chaplin, which Chaplin wrote and directed in 1915.)- https://en.wikipedia.org/wiki/The_TrampApple – Think Different Commercial- https://www.youtube.com/watch?v=4oAB83Z1ydEAnti-Monopoly (a board game made by San Francisco State University Professor Ralph Anspach in response to Monopoly. The idea of an anti-monopoly board game dates to 1903 and the original Monopoly created by Lizzie Magie.)- https://en.wikipedia.org/wiki/Anti-MonopolyAnti-Monopoly, Inc. vs. General Mills Fun Group, Inc. court case 1976–1985 (Starting in 1974, Parker Brothers and its then corporate parent, General Mills, attempted to suppress publication of a game called Anti-Monopoly, designed by San Francisco State University economics professor Ralph Anspach and first published the previous year.)- https://en.wikipedia.org/wiki/History_of_Monopoly#Anti-Monopoly.2C_Inc._vs._General_Mills_Fun_Group.2C_Inc._court_case_1976.E2.80.931985The Rageaholic - Begun, The Comic Film Crash Has - A Rant- https://www.youtube.com/watch?v=Dlk3-NtOFkkTerror Australis Podcast (TNC podcast)- https://anchor.fm/terror-australis-podcastShout Outs 9th August 2021 – 5th Anniversary of No Man's Sky - https://www.nomanssky.com/2021/08/no-mans-sky-5th-anniversary/No Man's Sky is easily one of the most infamous titles in video game history, thanks to its extremely rocky launch and poor state at release. The game lacked many of its core promised features when it launched, resulting in heavy fan backlash. Within two years of its rollout, the tide started turning in No Man's Sky's favor, thanks in large part to updates that transformed the experience. NEXT counted as the first of such changes, ushering in multiplayer gameplay options that Hello Games teased in the lead up to launch. This particular update also overhauled the graphics and introduced refined base-building mechanics. Hello Games' efforts didn't stop there either; as such, the redemption arc for No Man's Sky has been rather impressive to watch unfold. With the game now celebrating its fifth year anniversary, Hello Games has put out a short video looking back at all of the updates we've seen so far, along with a tease of what's coming next.9th August 2021 – 25th anniversary of Escape from L.A. - https://movieweb.com/escape-from-la-25th-anniversary/Stylized on-screen as John Carpenter's Escape from L.A. A 1996 American post-apocalyptic action film co-written, co-scored, and directed by John Carpenter, co-written and produced by Debra Hill and Kurt Russell, with Russell also starring as Snake Plissken. A sequel to Escape from New York, Escape from L.A. co-stars Steve Buscemi, Stacy Keach, Bruce Campbell, and Pam Grier. The film gained a strong cult following. The film was in development for over 10 years. At one point, a script was commissioned in 1987 and was written by screenwriter Coleman Luck, with Dino De Laurentiis's company producing. Carpenter later described the script as "too light, too campy". In time, Carpenter and Kurt Russell got together to write with their long-time collaborator Debra Hill. Carpenter insists that Russell's persistence allowed the film to be made, since "Snake Plissken was a character he loved and wanted to play again." At the beginning of the film, Kurt Russell wears his costume from the original film, which still fits after fifteen years. The film takes place in 2013.10th August 2021 – 60th Anniversary of Operation Ranch Hand, spraying an estimated 20 million US gallons (76,000 m3) of defoliants and herbicides over rural areas of South Vietnam in an attempt to deprive the Viet Cong of food and vegetation cover - https://en.wikipedia.org/wiki/Operation_Ranch_HandOperation Ranch Hand was a U.S. military operation during the Vietnam War, lasting from 1962 until 1971. Largely inspired by the British use of 2,4,5-T and 2,4-D (Agent Orange) during the Malayan Emergency in the 1950s, it was part of the overall herbicidal warfare program during the war called "Operation Trail Dust". Ranch Hand involved spraying an estimated 20 million U.S. gallons (76,000 m3) of defoliants and herbicides over rural areas of South Vietnam in an attempt to deprive the Viet Cong of food and vegetation cover. Areas of Laos and Cambodia were also sprayed to a lesser extent. Nearly 20,000 sorties were flown between 1961 and 1971. The herbicides were sprayed by the U.S. Air Force flying C-123s using the call sign "Hades". The planes were fitted with specially developed spray tanks with a capacity of 1,000 U.S. gallons (4 m3) of herbicides. A plane sprayed a swath of land that was 80 meters wide and 16 kilometers (10 mi) long in about 4½ minutes, at a rate of about 3 U.S. gallons per acre (3 m3/km2). Sorties usually consisted of three to five aircraft flying side by side. 95% of the herbicides and defoliants used in the war were sprayed by the U.S. Air Force as part of Operation Ranch Hand. The remaining 5% were sprayed by the U.S. Chemical Corps, other military branches, and the Republic of Vietnam using hand sprayers, spray trucks, helicopters and boats, primarily around U.S. military installations. The use of herbicides in the Vietnam War was controversial from the beginning, particularly for crop destruction. The scientific community began to protest the use of herbicides in Vietnam as early as 1964, when the Federation of American Scientists objected to the use of defoliants. In 1967, seventeen Nobel laureates and 5,000 other scientists signed a petition asking for the immediate end to the use of herbicides in Vietnam. According to the Vietnamese government, the US program exposed approximately 4.8 million Vietnamese people to Agent Orange, resulted in 400,000 deaths due to a range of cancers and other ailments. The Vietnamese population has suffered a range of ailments with three million Vietnamese people suffering health problems, one million birth defects caused directly by exposure to Agent Orange, and 24% of the area of Vietnam being defoliated.12th August 2021 – 40th birthday of the IBM 5150 - https://en.wikipedia.org/wiki/IBM_Personal_Computer#DebutOn August 12, 1981, Don Esteridge, who was unknown at the time, announced the release of the new personal computer created by his company. The head of development at IBM Entry Level Systems presented the 5150, or IBM PC, a concept that would revolutionize the computer industry forever. The machine was based on open architecture and a substantial market of third-party peripherals, expansion cards and software grew up rapidly to support it. The PC had a substantial influence on the personal computer market. The specifications of the IBM PC became one of the most popular computer design standards in the world, and the only significant competition it faced from a non-compatible platform throughout the 1980s was from the Apple Macintosh product line. The majority of modern personal computers are distant descendants of the IBM PC.Pricing started at $1,565 for a configuration with 16K RAM, Color Graphics Adapter, and no disk drives. The price was designed to compete with comparable machines in the market. For comparison, the Datamaster, announced two weeks earlier as IBM's least expensive computer, cost $10,000. IBM's marketing campaign licensed the likeness of Charlie Chaplin's character "The Little Tramp" for a series of advertisements based on Chaplin's movies, played by Billy Scudder. The PC was IBM's first attempt to sell a computer through retail channels rather than directly to customers. Reception was overwhelmingly positive, with sales estimates from analysts suggesting billions of dollars in sales over the next few years, and the IBM PC immediately became the talk of the entire computing industry. Dealers were overwhelmed with orders, including customers offering pre-payment for machines with no guaranteed delivery date. By the time the machine was shipping, the term "PC" was becoming a household name.Remembrances10th August 2010 - David L. Wolper - https://en.wikipedia.org/wiki/David_L._WolperAmerican television and film producer, responsible for shows such as Roots, The Thorn Birds, North and South, L.A. Confidential, and Willy Wonka & the Chocolate Factory (1971). He was awarded the Jean Hersholt Humanitarian Award at the 57th Academy Awards in 1985 for his work producing the opening and closing ceremonies of the XXIIIrd Olympiad, Los Angeles 1984 as well as helping to bring the games to L.A. His 1971 film (as executive producer) about the study of insects, The Hellstrom Chronicle, won an Academy Award. On March 13, 1974, one of his crews filming a National Geographic history of Australopithecus at Mammoth Mountain Ski Area was killed when their Sierra Pacific Airlines Corvair 440 slammed into the White Mountains shortly after takeoff from Eastern Sierra Regional Airport in Bishop, California, killing all 35 on board, including 31 Wolper crew members. The filmed segment was recovered in the wreckage and was broadcast in the television series Primal Man. The cause of the crash remains unsolved. In 1988, Wolper was inducted into the Television Hall of Fame. For his work on television, he had received his star on the Hollywood Walk of Fame. He died from congestive heart disease and complications of Parkinson's disease at the age of 82 in Beverly Hills, California.Famous Birthdays10th August 1889 – Charles Darrow - https://en.wikipedia.org/wiki/Charles_DarrowAmerican who modified the design of Lizzie Magie's original invention The Landlord's Game. He became the first millionaire game designer in history, and although Magie patented her invention she received only $500. Parker Brothers falsely credited Darrow as the original inventor. While Darrow eventually sold his version of Monopoly to Parker Brothers, claiming it to be his own invention, modern historians credit Darrow as just one of the game's final developers. Monopoly is a board game which focuses on the acquisition of fictional real estate titles, with the incorporation of elements of chance. After losing his job at a sales company following the Stock Market Crash of 1929, Darrow worked at various odd jobs. Seeing his neighbors and acquaintances play a board game in which the object was to buy and sell property, he decided to publish his own version of the game, with the help of his first son, William, and his wife Esther. Darrow marketed his version of the game under the name Monopoly. In truth, Darrow was just one of many people in the American Midwest and East Coast who had been playing a game of buying and trading property. The game's direct ancestor was The Landlord's Game, created by Elizabeth Magie. The Darrow family initially made their game sets on flexible, round pieces of oilcloth instead of rigid, square carton. Charles drew the designs of the properties with drafting pens, and his son and wife filled in the spaces with colors and made the title deed cards and Chance and Community Chest cards. In 1970, three years after Darrow's death, Atlantic City placed a commemorative plaque in his honor on The Boardwalk, near the corner of Park Place. In 1973 Ralph Anspach, an economics professor at San Francisco State University, produced Anti-Monopoly, a game similar to Monopoly, and for this was sued by Parker Brothers. He was born in Philadelphia, Pennsylvania.Events of Interest10th August 1960 – Dinosaurus! was released - https://www.imdb.com/title/tt0053768/ On this day in 1960, it was 'Jurassic Park' all over again with the release of Dinosaurus! The feature starred Ward Ramsey and Kristina Hanson, and here's the plot summary: "After undersea explosions near a Caribbean island, prehistoric creatures are unleashed on the unsuspecting population. Freed from his watery tomb, as well, is a very friendly Neanderthal man who proceeds to befriend a local orphan boy. The boy, Neanderthal and irritated dinosaur make for an interesting dramatic climax." The leading role was intended for Steve McQueen, who starred in The Blob two years earlier, also produced by Harris and directed by Yeaworth. McQueen passed on the film to make The Magnificent Seven instead. The dinosaurs were filmed using the technique of stop-motion animation as well as puppets for close-ups. The film promulgates the naïve idea that herbivorous animals (such as the brontosaurus) are not dangerous (a similar claim was made in Spielberg's 'Jurassic Park', 1993). The cape buffalo is one of the most aggressive and dangerous animals in Africa (and only weighs about 5% of what a brontosaurus is estimated to have weighed). Marcel Delgado was given less than half the time originally agreed upon to create the dinosaur models used in the film. The studio initially agreed to give him five to six weeks, as he requested, but two weeks later he was told that they would begin production on Tuesday. When Betty is captured by the neanderthal and taken to his cave, she's wearing a white dress and a pearl necklace. Combined with her red hair, she bears a striking resemblance to Wilma Flintstone, one of the stars of the TV cartoon series "The Flintstones" (1960), which would debut on American television one month after this movies US release (coincidentally, Betty is the name of Wilma's best friend).10th August 1990 – The Magellan space probe reaches Venus. - https://en.wikipedia.org/wiki/Magellan_(spacecraft)#Orbital_encounter_of_Venus On August 10, 1990, the American Magellan probe, named after the explorer Ferdinand Magellan, arrived at its orbit around the planet and started a mission of detailed radar mapping at a frequency of 2.38 GHz. It began the orbital insertion maneuver which placed the spacecraft into a three-hour, nine minute, elliptical orbit that brought the spacecraft 295-kilometers from the surface at about 10 degrees North during the periapsis and out to 7762-kilometers during apoapsis. During each orbit, the space probe captured radar data while the spacecraft was closest to the surface, and then transmit it back to Earth as it moved away from Venus. This maneuver required extensive use of the reaction wheels to rotate the spacecraft as it imaged the surface for 37-minutes and as it pointed toward Earth for two hours. The primary mission intended for the spacecraft to return images of at least 70 percent of the surface during one Venusian day, which lasts 243 Earth days as the planet slowly spins. To avoid overly-redundant data at the highest and lowest latitudes, the Magellan probe alternated between a Northern-swath, a region designated as 90 degrees north latitude to 54 degrees south latitude, and a Southern-swath, designated as 76 degrees north latitude to 68 degrees south latitude. However, due to periapsis being 10 degrees north of the equatorial line, imaging the South Pole region was unlikely. The resulting maps were comparable to visible-light photographs of other planets, and are still the most detailed in existence. Magellan greatly improved scientific understanding of the geology of Venus: the probe found no signs of plate tectonics, but the scarcity of impact craters suggested the surface was relatively young, and there were lava channels thousands of kilometers long.IntroArtist – Goblins from MarsSong Title – Super Mario - Overworld Theme (GFM Trap Remix)Song Link - https://www.youtube.com/watch?v=-GNMe6kF0j0&index=4&list=PLHmTsVREU3Ar1AJWkimkl6Pux3R5PB-QJFollow us onFacebook- Page - https://www.facebook.com/NerdsAmalgamated/- Group - https://www.facebook.com/groups/440485136816406/Twitter - https://twitter.com/NAmalgamatedSpotify - https://open.spotify.com/show/6Nux69rftdBeeEXwD8GXrSiTunes - https://itunes.apple.com/au/podcast/top-shelf-nerds/id1347661094Instagram - https://www.instagram.com/nerds_amalgamated/Email - Nerds.Amalgamated@gmail.comSupport via Podhero- https://podhero.com/podcast/449127/nerds-amalgamated See acast.com/privacy for privacy and opt-out information.

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Mike Kloser is a 61-year-old multisport athlete and entrepreneur who has won World Championships in mountain biking, adventure racing, and rogaine. Kloser lives in Vail, Colorado and offers backpacks and cycling tours through his company, OutThere USA. In this fun and personal conversation, Travis and Mace learn about Mike's early days in Iowa and his move to Vail in the 70s before laughing with him about tales of adventure from over the decades. We're proud to announce a partnership with OutThere USA; please see www.travismacy.com/podcast for 20% off our favorite packs.

We’re back folks! After a few months hiatus we are back in the studio here with Mike Kloser for episode #7 of the Find Your FORM Podcast. Mike is a 4 time Adventure Racing World Champion, Mountain Bike World Champion, 3 time Eco Challenge champion, 5 time Primal Quest champion, professional mogul skier, and all around endurance badass.

The name Mike Kloser and adventure go hand in hand. Mike has been seeking adventure his entire life. In 1988, Mike was crowned Mountain Bike Cross Country World Champion and throughout his cycling career stacked up an impressive resume of world cup wins and podiums as well as many other titles, including a silver medal in the Mountain Bike Downhill World Championships. Upon retiring from professional cycling, Mike went on to adventure racing. He won the Eco-Challenge 3 times, Primal Quest 5 times and won the World Championships 4 times. and he is still going, this past summer he added the Go Pro Games Ultimate challenge win to him palmeres. Just to add another fun fact to his resume, he is also a world champion in long distance orienteering. Mike is a man of many talents and his love for all things considered adventurous is contagious. Throughout Mike’s athletic career, he gained plenty of experience in coaching and guiding others. In addition to being a world champion athlete, dad and family man. Mike own’s Out There an adventure travel and gear company. http://www.mikekloser.com/ https://www.outthereadventuretravel.com/ --- Support this podcast: https://anchor.fm/executiveathletes/support

This week's guest is adventure racing legend Mike Kloser, who is one of the top adventure and endurance athletes of all time. Mike is a former mountain bike world champion and multi-time adventure racing world champ as well. Even though he is retired now, he still competes regularly in a number of events and even came back to take part in the new Eco-Challenge race that took place last fall. In the interview, Mike shares stories from throughout his career, tells us how he got started in adventure racing, and provides some insights on his friend Lance Armstrong too. We even discuss his latest venture, Out There Adventure Travel, which organizes cycling, mountain biking, and wellness trips to parts of Europe. This is just a small part of what we chat about, with a guy that both Dave and Kraig know very well. Before we jump into the interview, our intrepid co-hosts get us up to speed on the latest happenings from the world of mountaineering, where it looks like things have mostly come to a standstill thanks to the virus. The guys also discuss a major archaeological find in Mexico that was discovered thanks to the breakthrough technology known as Lidar. Then, they share a couple of dream jobs for the outdoor crowd, including a chance to get paid $1000 to watch a hunting show or $20,000 to hike the Appalachian Trail as the "Chief Hiking Officer"for a brewery.  Finally, they wrap things up in our Gear Segment with both Dave and Kraig sharing their thoughts on the VSSL survival kits. Dave recently got his hands on a VSSL First Aid Kit, while Kraig checks out the VSSL Camp Supplies model. Both come away very impressed with the design, build-quality, and contents of these impressive kits.  Show Notes GearLobo Application — $1000 to watch MeatEater Become the Chief Hiking Officer for Devil's Backbone Brewing Lost City of the Monkey God by Douglas Preston (Archaeology book referenced by Kraig)  

Christine Kloser has trained more than 70,000 entrepreneurs, leaders and authors to write their books through her inside out approach. She has written and co-authored twenty books and has been featured in the Los Angeles Times, Entrepreneur Magazine, FOX News, Forbes.com, Huffington Post and Entrepreneur.com, and is a regular columnist for the award-winning PUBLISHED Magazine. She coined the term “transformational author” and debuted it at her first Transformational Author Experience in 2011. The concept came about when she experienced a major setback in her business when she was straddling two different industries and found herself lost in the chasm between them. Grateful to have found an authentic and aligned way to blend the best of these two worlds and serve her community bigger and better than ever, her first class of TAE students numbered over 10,000, and she hasn’t looked back. Christine shares her story on Thrive LOUD with Lou Diamond. *** CONNECT TO LOU DIAMOND: www.loudiamond.net SUBSCRIBE TO THRIVE LOUD: www.thriveloud.com/podcast  

In this episode, Christine and David discuss:  Being an author and following your passion no matter what.  Learning from those that know.  The highs and lows of being an author.  The mistakes you will make along the way and overcoming the fear of imperfection.  Key Takeaways:  You are writing a book, you aren't going to […] The post 002 David Kloser: Doing What It Takes and Stepping Up to the Plate appeared first on Get Your Book Done.

In this episode, Christine and David discuss:  Being an author and following your passion no matter what.  Learning from those that know.  The highs and lows of being an author.  The mistakes you will make along the way and overcoming the fear of imperfection.     Key Takeaways:  You are writing a book, you aren’t going [...]

I sit down with Teresa Kloser, Technology Executive, and Eric Elkins, CEO and Chief Strategist of Wide Foc.us, to talk about the unique challenges of social media for companies - especially tech companies - and how to curate an effective presence, truly engage customers and create measurable, results-oriented engagement with thought leadership.★ Support this podcast on Patreon ★

A conversation with Prof. Jonathan Osborne Which aspects of science are most relevant to you, if you’re not planning to be a scientist? What knowledge is likely to be valuable and useful for day-to-day life? In this episode, we talk with Prof. Jonathan Osborne about useful and reliable knowledge, and about the importance of teaching and learning about procedural and epistemic aspects of scientific inquiry. Prof. Osborne is Kamalachari Professor of Science Education at Stanford University, and the Chair of the OECD PISA Science Expert Group.   Personal website: https://ed.stanford.edu/faculty/osbornej   Further reading: Erduran, S., & Dagher, Z. (2014). Reconceptualizing the Nature of Science for Science Education. Dordrecht, The Netherlands: Springer. Kloser, M. (2016). Alternate text types and student outcomes: an experiment comparing traditional textbooks and more epistemologically considerate texts. International Journal of Science Education, 38(16), 2477-2499. doi: 10.1080/09500693.2016.1249532 Yarden, A., Norris, S., & Phillips, L. (2015). Adapted primary literature: The Use of Authentic Scientific Texts in Secondary Schools. Dordrecht, The Netherlands: Springer.

MC KIE Presents' Podcast Vol 32 with Kloser Deal

join us this week for kathleen biffle and kathleens Kloser look segment ,Also we have Rich Cooley and cooleys corner ,Shad Biffle with metal prices and birthdays and events, Also the indiana gold hunter Dennis Dayton, and your host Tim Grimes we hope you enjoy the show and be sure to check out our patreon page if you would like to help support the show thank you all

join us this week for kathleen biffle and kathleens Kloser look segment ,Also we have Rich Cooley and cooleys corner ,Shad Biffle with metal prices and birthdays and events, Also the indiana gold hunter Dennis Dayton, and your host Tim Grimes we hope you enjoy the show and be sure to check out our patreon page if you would like to help support the show thank you all

join us for yet another great show ,this week with kathleen biffles Kloser look with kathleen ,also we have rich Cooley our producer Shad Biffle ,The indiana Gold hunter Dennis Dayton and your host Tim Grimes we hope you enjoy the show and thanks for tuning in

join us for yet another great show ,this week with kathleen biffles Kloser look with kathleen ,also we have rich Cooley our producer Shad Biffle ,The indiana Gold hunter Dennis Dayton and your host Tim Grimes we hope you enjoy the show and thanks for tuning in

In this episode, Devi chats with Christine Kloser about how to "Get Your Book Done". Christine is an international speaker on the topic of transformational authorship, and transformational leadership. She is the founder of the Transformational Author Experience, and author of thirteen books, including the best-selling and award-winning books, Conscious Entrepreneurs, The Freedom Formula, Pebbles In The Pond and Get Your Book Done. Devi and Christine discuss: The "Transformation Quadrant" and how you can use it to map out your book SELF (Upper Left): What is the transformation that you want for yourself through your book? READER (Bottom Left): What is the transformation that you want for your reader? BUSINESS (Upper Right): What is the transformation that you want for your business? WORLD: (Bottom Right): What is the transformation that you want your book to have in the world? The success secret of writing your book for only one person The Three Big "Whys" Why are you writing the book? Why you? Why now? Your Life is a roadmap leading to the destination of your book Creating your book’s North star by writing your back cover copy, first: Who is your book for? How are you going to help them? What kinds of a result are you going to deliver? What may be possible in their life, from reading the book? What goes on the back of your book: Headline Descriptive Paragraphs Bullet points Short Author Bio Endorsements Writing your dream endorsements How to get endorsements How to utilize endorsements to help your book popularity on your Amazon page, your website, and press releases Self-publishing, hybrid publishing, vs. traditional publishing What traditional publishers are looking for in new authors The difference between “available in bookstores” and “in bookstores” What happens if your book doesn’t fly off of the shelves in a bookstore after it is published How to leverage your book, as a speaker How to use your book to build your list Inviting the reader to take the "next step" with you Creating a simple companion to your book The importance of not making your book look like an advertisement Sharing success stories in your book Coming from a place of service How long it typically takes to write and publish a book How to brainstorm and organize your book with index cards and a spreadsheet The importance of trusting that part of you that is deeper than reason, that doesn’t need approval, that knows what you know what you know, even if it goes against the grain. and more… Learn More about Christine: A master facilitator and trainer on discovering your core message, writing your transformational book, and making a difference as a leader in the world, Christine has trained 70,000 writers in more than 125 countries. Christine facilitates her premier My Time to Write author mentorship program for members around the world, teaches her signature Get Your Book Done program online to thousands, and facilitates transformational writing retreats throughout the year... including fabulous destinations like Costa Rica, and Tulum, Mexico! Connect with Christine on her website @ ChristineKloser.comGet her aspiring author action guide @ freegiftfromchristine.comReach out with inquiries to info@christinekloser.com On Facebook: @ ChristineKloserFanPage On YouTube: @ www.youtube.com/user/ChristineKloser Resources Mentioned:The Freedom Formula: How to Put Soul In Your Business and Money in Your Bank  by Christine Kloser The Miracle Morning by Hal Elrod

The vast majority of us have talked about writing a book. Problem is, the vast majority of us never make time to sit down and get the words on the page. Christine Kloser got immersed in publishing when her husband decided to write a book involving interviews with Major League Baseball players. She pored over Dan Poynter's Self-Publishing Manual, learning the nuts and bolts of putting a book together to assist her husband in becoming a published author. At the same time, Kloser was involved in the leadership of the Network for Empowering Women Entrepreneurs, and she often heard members talk about becoming authors—yet fail to take action. She decided to apply her knowledge of the writing process and help these women get published: Kloser offered to compile the book if each woman would agree to write one chapter. That book, entitled Inspiration to Realization, made the 2005 Entrepreneur Magazine's list of top reads for women, and soon other women were begging Kloser for help in writing a book of their own. Inspired to create a company that would help people write transformational books, Kloser designed the Get Your Book Done process. Ten years later, she has trained 70,000 writers in more than 125 countries, serving as a master facilitator and trainer in the area of excavating your message and writing books that positively impact the world. She is an international speaker and the author of 13 books herself, including best-sellers and award-winners such as Conscious Entrepreneurs, The Freedom Formula, and Pebbles in the Pond. Today she describes the first steps in becoming a transformational author, the structure of her Get Your Book Done process, and why it's important to write without editing. Key Interview Takeaways The first step in writing a transformational book is to ask yourself what transformation you want for yourself, your reader, your business, and the world. Kloser recommends defining the change you want as a result of your book and writing for your ideal reader. Kloser's firm affords aspiring writers the opportunity to build the necessary foundation, develop an appropriate outline, and design a plan to sit down and write. Her online course, coaching practice and writing retreats guide clients through this eight-module process. You don't necessarily have to be a writer to be an author. If you have a message and you are willing to practice, you can write a book. Give yourself permission to write an SFD. Kloser compares the writing process to that of a potter at the wheel: The writer's ‘shitty first draft' is like the initial messy clump of clay. Once you get the words on the page, they can be shaped into something beautiful. Connect with Christine Kloser Learn more about your ad choices. Visit megaphone.fm/adchoices

Austrian musician, film composer, producer, and screenwriter Harald Kloser began his career in Europe playing in a band and collaborating with pop artists such as Falco. As a musician he appeared on recording projects by Tom Waits, Jose Feliciano, Elton John, Al Jarreau, and others. After a career scoring for television, Harald eventually broke through to national prominence with his work on Alien vs. Predator and the sci-fi disaster film The Day After Tomorrow, starring Dennis Quaid and Jake Gyllenhaal. Both films were directed by Roland Emmerich, with whom Kloser went on to work on 10,000 B.C. and 2012, starring John Cusack. Though the two films were scored by Harald, he also co-wrote the scripts with Emmerich. In addition to creating the score for the movie Anonymous, Harald served as both composer and film producer on the recent hits White House Down, starring Jamie Foxx and Channing Tatum, and Independence Day: Resurgence, starring Liam Hemsworth and Jeff Goldblum. He has won three BMI Film & TV Awards for Alien vs. Predator, The Day After Tomorrow, and 2012. 

Mike was the captain of Team Nike Adventure Racing where his results include but are definitely not limited to four World Championships, Three Eco-Challenge titles, and five Primal Quest Championships. Check out Mike's meister profile: www.mtnmeister.com/mike-kloser

What needs to be said about Mike. He's is a world class athlete and a really nice guy and has some cool stories This weeks links Out There Packs http://www.outthereusa.com/ Legendary Reviews http://youtu.be/kQAgJhiamoE iTunes https://itunes.apple.com/us/podcast/ta-1/id806458953?mt=2

Listen as Patricia interviews Christine Kloser, award-winning author of The Freedom Formula and creator of the Freedom Formula Experience. Christine will show you How to Put Soul in Your Business and Money in Your Bank! Even during periods of prosperity, the relevancy of spirituality to business success tends to be ignored. On the brink of bankruptcy, Kloser discovered if you ignore such a powerful and dynamic force, you may never achieve reach your full potential in business and your personal life. She was able to quickly turn her business ideas into reality and build a seven-figure enterprise in one of the worst economies since the Great Depression. Also joining us is Peter J D'Adamo who is a second-generation naturopathic physician noted for his popular books on the Blood Type Diet.

Listen as Patricia interviews Christine Kloser, award-winning author of The Freedom Formula and creator of the Freedom Formula Experience. Christine will show you How to Put Soul in Your Business and Money in Your Bank! Even during periods of prosperity, the relevancy of spirituality to business success tends to be ignored. On the brink of bankruptcy, Kloser discovered if you ignore such a powerful and dynamic force, you may never achieve reach your full potential in business and your personal life. She was able to quickly turn her business ideas into reality and build a seven-figure enterprise in one of the worst economies since the Great Depression. Also joining us is Peter J D'Adamo who is a second-generation naturopathic physician noted for his popular books on the Blood Type Diet.