Podcasts about Midas

Welcome back to another episode of The Insurance Dudes! Craig and Jason sit down with the energetic and insightful Julian Chambers. From his early days dabbling in network marketing straight out of high school, to finding his stride in life insurance and then crushing it in Medicare sales, Julian shares his journey as a young entrepreneur in the insurance world.You'll hear firsthand about the mindset shifts, personal development rituals inspired by Tony Robbins and Grant Cardone, and the actionable strategies that helped Julian go from rookie uncertainty to writing ten Medicare Advantage policies a week.If you're an agent looking to up your game or just need a dose of motivation, you won't want to miss this episode packed with real talk, practical tips, and a whole lot of inspiration. Let's dive in!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

The media landscape is noisier than ever. How can founders and business leaders get their stories heard? And in an age of AI-driven content, how can creators distinguish themselves and build a direct relationship with their audience? In this episode, CJ sits down with Alex Konrad, a longtime tech journalist, former Forbes editor (responsible for curating the renowned Forbes 30 Under 30, Cloud 100, and Midas lists), and founder of Upstarts, a newsletter covering startups, venture capital, and the people shaping the innovation economy. Alex shares insider stories from his decade at Forbes, including how lists like the “30 Under 30” were created and what it was like profiling (and sometimes singing karaoke with) the likes of Marc Benioff, Satya Nadella, and Sam Altman. The conversation explores the evolving landscape of media, the business fund-raising announcements, how startups can actually work with journalists to shape perception, the rise of VC firms as media powerhouses, the shifting role of platforms like Substack and LinkedIn, why relationship-driven content will outlast the race to break news, and the death of traditional SEO.—LINKS:Alex Konrad on LinkedIn: https://www.linkedin.com/in/alexrkonradAlex Konrad on X (@alexrkonrad): https://x.com/alexrkonradUpstarts Media: CJ on X (@cjgustafson222): https://x.com/cjgustafson222Mostly metrics: LINKS MENTIONED:No Priors: AI, Machine Learning, Tech, & Startups: https://www.youtube.com/@NoPriorsPodcastLatent Space: https://www.youtube.com/@LatentSpacePodThe Daily: https://www.nytimes.com/column/the-daily52 Sourcery with Molly O'Shea https://www.youtube.com/@SourceryVCThe Information: https://www.nytimes.com/column/the-dailyRELATED EPISODES:“Let's Just See What Breaks” — Intuit's CFO on Being a Disruptor When You're Already the Incumbent - —TIMESTAMPS:(00:00) Preview and Intro(02:32) Sponsor – Navan | Rillet | Pulley(07:13) Building the Forbes 30 Under 30, Cloud 100, and Midas List(11:49) The Meme of SEC Trouble on Forbes List and a Media Tip(14:08) Why Lists Work So Well(17:17) Sponsor – Brex | Aleph | RightRev(21:57) What Might Convince Alex To Start a List(23:13) Karaoke With Benioff & Interacting With Billionaires(29:14) Entrepreneurship & Work-Life Integration(33:25) Sales Skills Alex Learned as a Founder(37:56) The Dance Behind Fundraising Announcements(42:30) How To Capitalize on the Media Outside of Funding Rounds(45:24) Examples of Founder “Oh S**t!” Moments(47:58) VC Firms As Media Companies(51:16) Non-Journalists Interviewing in Tech(55:02) Audience Relationship & Guarding Against AI(57:41) The Death of SEO(1:00:45) The Value of Time Sensitivity and News in the Era of AI(1:02:40) Platform Relationships & Substack(1:04:55) Bootstrapping Media & VC Pressure(1:10:55) Wrap—SPONSORS:Navan is the all-in-one travel and expense solution that helps finance teams streamline reconciliation, enforce policies automatically, and gain real-time visibility. Visit https://navan.com/runthenumbers for your demo.Rillet is the AI-native ERP modern finance teams are switching to because it's faster, simpler, and 100% built for how teams operate today. See how fast your team can move. Book a demo at https://www.rillet.com/metrics.Pulley is the cap table management platform built for CFOs and finance leaders who need reliable, audit-ready data and intuitive workflows. Switch in as little as 5 days and get 25% off your first year: https://pulley.com/mostlymetrics.Brex offers the world's smartest corporate card on a full-stack global platform. Plus, they offer modern banking and treasury as well as intuitive expenses and accounting automation, bill pay, and travel. Find out more at https://www.brex.com/metricsAleph automates 90% of manual, error-prone busywork, with the power of a web app, the flexibility of spreadsheets, and the magic of AI. Get a personalised demo at https://www.getaleph.com/runRightRev automates the revenue recognition process from end to end, gives you real-time insights, and ensures ASC 606 / IFRS 15 compliance—all while closing books faster. For RevRec that auditors actually trust, visit https://www.rightrev.com and schedule a demo.#TechJournalism #MediaStrategy #AIinMedia #StartupPR #FutureOfMedia This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.mostlymetrics.com

The Chase Center has been a fun spot this summer, and that's not just because of the Valkyries. Every Thursday there's been a music-fueled party happening outside of the arena. It's called “Thrive at Five.” Bay Area DJ Anthony Midas has been spinning records there all summer. He spoke with KALW's Jenee Darden about the weekly event and his love for R&B music. 

This week's BIZARRE royal revelations! King Charles UNDERCUTS Meghan's jam prices at just $6.70 versus her $14 offering while being STALKED BY A PANTHER near Highgrove House! Meanwhile, Meghan gets SNUBBED by Mariah Carey who only mentions Sarah Ferguson when asked about royals, plus cooks pasta wearing $300,000 worth of jewelry! Kate and William plan FRESH START move to Forest Lodge after "difficult times" at Adelaide Cottage during her cancer battle! Harry feels "LOST" with his "brown Midas touch" of failed ventures while quietly honoring grandfather Philip at VJ Day memorial! Plus: Buckingham Palace DELETES Princess Anne birthday post after claiming she has stepchildren who don't exist, Charles powers Sandringham with solar farm, and church choir branded "UNHOLY DIN" by official inquiry!

Welcome back to The Insurance Dudes! In this episode, we're joined by Don Wilson, the dynamic founder and owner of Capital Insurance Group. Don's journey is as compelling as it is inspiring—he went from running retail clothing stores in West Virginia to leading a multi-state insurance agency with the mantra of authentic leadership and relentless persistence.Don shares wild tales from the trenches, including a not-to-be-missed story involving a would-be client with “grenades”—plus some runaway police chases tossed in for good measure.But it's not all war stories and dad jokes (of which Don delivers his top three). We dig deep into Don's business philosophy—why branding matters, how focusing on your target demographic leads to agency growth, and the importance of building a culture that puts employees first. Don's passion for mentorship, creativity in prospecting (think “Big Check Express” and the “pastry guy”), and commitment to authentic connections will fire up anyone in the insurance biz—or anyone thinking of making a leap in their career.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Episode 22In this podcast, professional astrologers Chani Nicholas, Thea Anderson, and Eliza Robertson look to the sky to make sense of what's happening here on Earth.This special episode is entirely dedicated to Pallas Athena — the asteroid and warrior goddess known for her strategic genius. We start by unpacking her many myths, including the famous story of her birth from Zeus' head, her role in the beheading of Medusa, and her origins in ancient Libya. Then we get into the astro of it all. We break down how Pallas Athena became one of the four asteroid goddesses, and how the archetypal warrior queen manifests in your birth chart. And finally, we look at the charts of major icons with prominent Pallas placements — like Amelia Earhart, Nina Simone, Issa Rae, and Britney Spears — and dig into the ways they each used intelligence, independence, and innovation to their advantage. Ready to enter your strategy era? Pull up your chart in the CHANI app (yes, your Pallas Athena readings have arrived), and welcome Pallas Athena into the chat.Content warning: sexual assault, domestic violenceTimestamps:(00:00) - Welcome to Down to Astro episode 22(00:50) - An introduction to Pallas Athena(11:16) - Mythological origins and evolution of Pallas Athena(23:46) - Pallas Athena's role in Greek tragedy(25:00) - The complexities of Pallas Athena's relationship with the patriarchy(27:16) - Athena and the betrayal of Medusa(36:31) - Pallas Athena and the archetype of the virgin goddess(39:12) - Pallas Athena's astrological significance(41:06) - The astronomy of the asteroid Pallas Athena(45:39) - Amelia Earhart: aviation and Athena on the ascendant(54:15) - Audre Lorde: “poetry is my primary weapon”(01:00:28) - Nina Simone: child prodigy and musical genius(01:13:09) - Diana Ross: international icon and innovato(01:15:17) - Issa Rae: “Insecure” and strategizing in communit(01:21:38) - Miley Cyrus: Pallas vs. Billy Ray Cyrus(01:24:01) - Britney Spears: a legal battle for freedom(01:27:24) - Tina Turner: superstar, sensation, survivor(01:34:12) - Lucy Lawless: TV's warrior princess(01:43:02) - How to work with Pallas Athena in the CHANI appThis episode was recorded on 7/30/2025.For more astrological insights, download the CHANI app or follow CHANI on Instagram, TikTok, and Bluesky.The song “Midas,” featured in the podcast, was created by NISHA and is available wherever you listen to music.This episode also mentioned the following creative works:“Asteroid Goddesses: The Mythology, Psychology, and Astrology of the Re-Emerging Feminine” by Demetra George and Douglas Bloch“Circe” by Madeline Miller“Flowers” by Miley Cyrus“Hit Me Baby One More Time” by Britney Spears“Insecure” (2016-2021) TV series created by Issa Rae“Metamorphoses” by Ovid“The Mis-Adventures of Awkward Black Girl” (2011-2013) Web series created by Issa Rae“Mississippi Goddam” by Nina Simone“The Oresteia” by Aeschylus“What's Love Got To Do With It?” (1993) Film directed by Brian GibsonP.S. The transcript for this episode is available here.

Welcome to another episode of The Insurance Dudes! In this candid and insightful conversation, hosts Jason Feltman and Craig Pretzinger are joined by Brandon Wolfe, Managing Partner at Jordan Partners, to dive deep into the world of insurance agencies and private equity.Ever wondered if insurance is the "legalized mafia" of finance, or why so many private equity investors are drawn to this industry? You'll get the inside scoop on what makes insurance such a unique — and investable — business, plus why slow, steady growth always wins the game.Hear Brandon break down the differences between captive and independent agencies from a private equity perspective, and learn what it really takes to get your agency "tuned up" and ready to sell.Whether you're thinking about selling, scaling, or just staying relevant in today's rapidly changing landscape, Brandon's experience negotiating deals and growing businesses offers a refreshing dose of reality and optimism for agency owners at any stage.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

One cold DM in February turned into Midas store #35.Then we gave ourselves nine days to open it. In this episode, I break down exactly how we pulled it off compressing an 8-week process into 10 days, running parallel tasks, and pushing every lever to hit peak-season revenue fast.You'll hear the real numbers, the systems we used, and why the winners in business get fired up by starting from zero, not by dreaming about “someday.”Send me a textDownload my FREE 8-Figure Playbook This playbook walks through the exact process I used to build from $0 in 2016 to $50M+/year today across multiple franchise brands Grab it here: https://brianbeers.kit.com/b79cf77012 Let's connect: Find me on X InstagramLinkedInYouTube

Getting caught up with everything going on in our Midas business34 (now 35 shops)$1M+ sales weekI've become irrelvantSend me a textDownload my FREE 8-Figure Playbook This playbook walks through the exact process I used to build from $0 in 2016 to $50M+/year today across multiple franchise brands Grab it here: https://brianbeers.kit.com/b79cf77012 Let's connect: Find me on X InstagramLinkedInYouTube

On today's show, what it takes to put on a big music festival like Outside Lands, then a local DJ throws R&B parties and a documentary about the late blues/folk/jazz singer Barbara Dane.

"Olaylar bizi incitemez, bizi incitebilen sadece olaylara karşı olan bakış açımızdır" diyen Marcus Aurelius'un felsefesi, günümüz yatırımcılarına korku ve açgözlülük duygularıyla nasıl başa çıkabileceklerini öğretiyor. Bu bölümde, Stoacılığın erdem, kontrol ve algı prensiplerini finansal piyasalara uygulayarak, piyasa çalkantıları karşısında sarsılmaz bir zihinsel kale inşa etmenin yollarını araştırıyoruz. Gerçek zenginliğin portföy büyüklüğünde değil, "stresten arınmış bir zihin ve kararlarımızı bağımsız alabilme yeteneği" olduğunu savunan Stoacı bakış açısıyla, yatırım yolculuğunuzu dönüştürecek içgörüler sunuyoruz. İyi dinlemeler! Midas uygulamasını indir: ⁠⁠https://app.getmidas.com/gmih/mie6gpeu⁠⁠ X (Twitter): ⁠⁠https://twitter.com/getmidas⁠⁠ Instagram: ⁠⁠https://www.instagram.com/get_midas/⁠⁠ YouTube: ⁠⁠https://www.youtube.com/@midasplus⁠⁠ TikTok: ⁠⁠https://www.tiktok.com/@midasinkulaklari⁠⁠ Midas'ın Kulakları: ⁠⁠https://www.getmidas.com/midasin-kulaklari⁠⁠ Not: Bu içerik, içeriğin yayınlandığı günkü veriler ve haberler baz alınarak hazırlanmıştır. Eğer varsa içerikte geçen hedef fiyat tahminleri, uzman ve analist yorumları bu içeriğin yayınlandığı tarihte geçerlidir. Bu tahmin ve yorumlar zaman içinde değişkenlik gösterebilmektedir. Bu podcast'te yer alan haberler ve haberlerin içerdiği şirketler hakkındaki bilgiler yatırım danışmanlığı kapsamında değildir. Bahsi geçen hisselerdeki; hisse adı, fiyatı ve grafikleri de dahil temsilidir, yatırım tavsiyesi değildir.

MIST009 - Space Biology - Midas (w/ Sunju Hargun & Evigt Mörker Remixes) Release Date: September 2, 2025 (12" & Digital) Buy: https://surethingrec.bandcamp.com/album/midas A1. Midas A2. Midas (Sunju Hargun Remix) B1. Error Box B2. Error Box (Evigt Mörker Remix) Sure Thing welcomes the Warsaw-based, Ukrainian artist Space Biology to the label, who delivers an elegant and enigmatic two-tracker that blurs the boundaries between the organic and the incorporeal, rendering phantoms into illusive sonic ephemera. Two remixes from Thailand's Sunju Hargun and Sweden's Evigt Mörker complete the vision, reconfiguring each original track in masterful and signature style and bringing new energies to focus. Written and Produced by Space Biology. Remixes by Sunju Hargun and Evigt Mörker. Mastered by Giuseppe Tillieci at Enisslab. Artwork by Kia Tasbihgou.

"Küçük parayla ev sahibi olmak" vadeden gayrimenkul sertifikaları, yatırım dünyasının ilgi çeken yeni enstrümanlarından biri. Bu bölümde, özellikle Damlakent projesi üzerinden, sertifika sisteminin işleyişini, asli ve talihi edinim farklarını, iskonto yokluğunun etkilerini ve paranın zaman değeri hesabını detaylıca inceliyoruz. Ev hayalini metrekare metrekare biriktirmek isteyenler için bu yatırım aracının gerçek potansiyelini ve gizli risklerini ortaya koyuyoruz. İyi dinlemeler. Midas uygulamasını indir: ⁠⁠⁠https://app.getmidas.com/gmih/mie6gpeu⁠⁠⁠ X (Twitter): ⁠⁠⁠https://twitter.com/getmidas⁠⁠⁠ Instagram: ⁠⁠⁠https://www.instagram.com/get_midas/⁠⁠⁠ YouTube: ⁠⁠⁠https://www.youtube.com/@midasplus⁠⁠⁠ TikTok: ⁠⁠⁠https://www.tiktok.com/@midasinkulaklari⁠⁠⁠ Midas'ın Kulakları: ⁠⁠⁠https://www.getmidas.com/midasin-kulaklari⁠⁠⁠ Not: Bu içerik, içeriğin yayınlandığı günkü veriler ve haberler baz alınarak hazırlanmıştır. Eğer varsa içerikte geçen hedef fiyat tahminleri, uzman ve analist yorumları bu içeriğin yayınlandığı tarihte geçerlidir. Bu tahmin ve yorumlar zaman içinde değişkenlik gösterebilmektedir. Bu podcast'te yer alan haberler ve haberlerin içerdiği şirketler hakkındaki bilgiler yatırım danışmanlığı kapsamında değildir. Bahsi geçen hisselerdeki; hisse adı, fiyatı ve grafikleri de dahil temsilidir, yatırım tavsiyesi değildir.

Thomas Winmill, manager of the Midas Discovery Fund and the Bexsil Investment Trust, says that while the rally in gold is long in the tooth — at record highs having lasted twice as long as the standard rally — but he makes the case that it still has plenty of room to run, boosted by purchases made by central banks around the world. Winmill says that a rising dollar might end the rally, but that's not in his forecast; he sees rates staying low or stable, providing enough fuel that the price of gold-mining stocks "could be a triple from here." David Trainer, founder and president at New Constructs, puts Peloton Interactive back into The Danger Zone, noting that the company — which is reporting earnings this week — has turned into a meme stock that has doubled its price from recent lows, but which hasn't improved a negative economic book value, meaning the current rally could be the proverbial dead-cat bounce. Lester Jones, chief economist for the National Beer Wholesalers Association discusses the latest Beer Purchasers Index, which showed a big decline from a year ago — meaning there could be an economic slowdown ahead — but a big improvement from the numbers released a month ago, which would signal that buyers are in a "holding pattern" waiting on tariff and other news before making purchase decisions. Plus, Chuck goes off the news on how a "boring" July that saw the market reach 10 record highs may have been setting up a rough August, and how the numbers could be tougher to get a read on depending on government changes in the future.

Welcome back to The Insurance Dudes! In this compelling episode, host Craig Pretzinger and co-host Jason Feltman sit down with Kathy Hitchcock from the Hitchcock Insurance Group in Rome, Georgia. Kathy shares her remarkable journey as a young scratch agent, opening her agency in 2015 just months before facing back-to-back rate hikes and near-impossible market conditions.Through honest stories about crying on her daily commute, the grit it took to build a thriving business, and insights into weathering tough insurance cycles, Kathy pulls back the curtain on what it really means to persevere as an agency owner. This episode dives deep into the challenges of scaling, hiring, and motivating a winning team—and how to create true work-life harmony when the business never really shuts off.Whether you're just starting your insurance journey or looking for fresh perspective on leadership, culture, and adapting to change (including a candid take on AI's impact), Kathy's story is packed with valuable lessons and real-world strategies for building a resilient, profitable insurance agency. Tune in for one of our most authentic discussions yet!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

A edição desta semana do Autores e Livros, da Rádio Senado, mistura comédia romântica, memórias familiares e poesia. Na entrevista, uma conversa com Ray Tavares sobre o romance “O Roteiro do Amor”, uma história divertida e apaixonante que se passa nos bastidores do cinema. A autora fala sobre personagens com maturidade emocional, tensão romântica e o desafio de abrir mão do controle quando o coração decide reescrever a história. Outro destaque é “Diante da manta do soldado”, de Lídia Jorge. O romance, que acaba de chegar ao Brasil pela Autêntica Contemporânea, mergulha nas memórias fragmentadas de uma mulher que retorna à antiga casa da família em busca de sua identidade. Com lirismo e densidade emocional, a autora portuguesa recria um cenário marcado por silêncios, afetos e interditos familiares. O programa ainda traz a estreia do publicitário Thiago Alves na literatura infantojuvenil, com “Em Busca da Pedra de Midas”, e uma dica de leitura provocadora com “Chega de Mimimi”, de Adriana Gattermayr. Para fechar, a poesia do quadro Encantos de Versos reúne autores portugueses em torno do tema “a busca”.

The latest episode of Get Physical Radio comes from Italian artist Clara, who brings a fresh perspective to the label's roots with a mix that digs deep into its early catalogue.Fresh off her debut release ‘Richi&Anto33', Clara delivers a nostalgic yet vibrant journey, highlighting timeless classics from the early 2000s. Her mix features standout cuts from M.A.N.D.Y., DJ T., Jona, and Chelonis R. Jones, as well as gems like ‘My Drums' by Tomas Barfod and the Tiefschwarz Reset Mix of ‘Sunsetpeople'.Balancing old-school energy with warm, contemporary moments, this is a heartfelt tribute to the foundation of the Get Physical sound, seen through Clara's unique lens.01 Karol XVII & MB Valence, Keely Timlin – Bang Bang feat. Keely Timlin (Back to 2013 Mix)02 Chelonis R. Jones – I Don't Know (Justus Köhncke Dub)03 Midas 104 – Simplicity04 Tomas Barfod – My Drums05 M.A.N.D.Y. – Achaat06 Jona – Full Pool07 M.A.N.D.Y. – Don't Stop08 Chelonis R. Jones – The Rush – Sex With The Machines09 DJ T. – Electrofied10 DJ T. – Starlit11 M.A.N.D.Y. – Sunsetpeople (Tiefschwarz Reset Mix)12 Chelonis R. Jones – One And One13 Andrea Ljekaj, Je Veux – Wonders Never Cease (Jimpster Dub Remix)14 Roland Leesker – Keep On Hosted on Acast. See acast.com/privacy for more information.

“The King of Clubs” Jason Midas returns to Windy City Slam Podcast to discuss his new venture, Pro Wrestling Sometimes' “The Jason Midas Experiment,” wrestling and rave show coming to Logan Square Auditorium, he breaks down the wrestling card and musical talent, he also discusses some of the latest in Freelance Wrestling and filling in for Kirby “The Voice” Alexander. Plus, Mike reflects on the life of Hulk Hogan, recaps “A Day For Priest,” a special show in honor of “The Underwear Model” Eric Priest and all of the emotion of that event and previews WWE SummerSlam, DREAMWAVE weekend, 2econd Wrestling and Wrestle League. Mike Pankow is a 25-year-plus professional journalist and wrestling superfan who covers local Chicagoland wrestling and national promotions like AEW and WWE. If there is something going on in Chicago, Mike knows about it. Enjoy "Wrestling, Chicago-Style" on The Broadcast Basement On-Demand Radio Network! Music by Jason Shaw on Audionautix.com. Get your local wrestling fix every Tuesday everywhere podcasts can be found and always at WindyCitySlam.com!

Det senaste rappåret har präglats av konflikten mellan Kendrick Lamar och Drake och den här sommaren kommer de båda till Sverige. Lyssna på alla avsnitt i Sveriges Radio Play. Under sommaren har vi på P3 Musikdokumentär dykt ner i vårt arkiv och valt ut ikoner som är aktuella på nytt och här bjuder vi på berättelsen om rappens kung Midas. Vi hoppas att du njuter av det här guldkornet som är en repris av P3 Musikdokumentär om Drake från 2019.Dokumentären är gjord av Axel WinqvistProducent: Vendela LundbergExekutiv Producent: Ulla Svensson Tekniker: Fredrik NilssonProgrammet är en produktion från Tredje Statsmakten Media

Bapcor, the company behind Autobarn, Burson and Midas, has issued a major profit warning, three directors have quit, and its share price has nosedive. Paramount has finally merged with Skydance in an $8 billion USD deal after close to 2 years of negotiations. LVMH has seen its share price fall more than 8% after investors get major tariff anxiety. _ Learn more about iShares by BlackRock here Download the free app (App Store): http://bit.ly/FluxAppStore Download the free app (Google Play): http://bit.ly/FluxappGooglePlay Daily newsletter: https://bit.ly/fluxnewsletter Flux on Instagram: http://bit.ly/fluxinsta Flux on TikTok: https://www.tiktok.com/@flux.finance —- The content in this podcast reflects the views and opinions of the hosts, and is intended for personal and not commercial use. We do not represent or endorse the accuracy or reliability of any opinion, statement or other information provided or distributed in these episodes.__ Issued by BlackRock Investment Management (Australia) Limited ABN 13 006 165 975, AFSL 230 523. Refer to FSG available on our website. Before making any investment decisions, you should assess whether the product or service is appropriate for you and read the PDS and TMD available at blackrock.com.au.See omnystudio.com/listener for privacy information.

Tune in to this episode of the Security Token Show where this week Herwig Konings, Kyle Sonlin and guest contributor Adrian Alvarez, CEO of InvestReady, cover the industry leading headlines and market movements, including the GENIUS Act being voted into law, stock lending on Kamino, and more RWA news!   Company of the Week - Herwig: Kamino Finance Company of the Week - Kyle: BioSig   Companies in the news include The House of Representatives, Kamino, xStocks/ Backed Finance, Spiko, Falcon Finance, Superstate, HUMO, Gemini, KN Group, AlloyX, Prypco, abrd, Lloyds, Hedera, Archax, MirrorRSV, OpenEden, Particula, NEXBRIDGE, Citi, J.P.Morgan, Northern Trust, Swift, Canton Network, B2C2, Cumberland DRW, FalconX, GSR, Midas, Etherlink, Chainlink, Blockchain Association, Ondo, BNB Chain, Brickken, Theo, ULTRA/ Wellington Management, Libeara, Pineapple, Inc., DeFi Dev Corp., Solana, Pop Social, AssetMint, BioSig Technologies, CXG   ===   TokenizeThis 2025 Conference Review: https://docsend.com/v/k8bn7/tt25  STM Predicts $30-50T in RWAs by 2030: https://docsend.com/view/7jx2nsjq6dsun2b9    More STM.co Reports: https://reports.stm.co/  Join the RWA Foundation and Read the Whitepaper: RWAF.xyz  Learn More About WALLY DAO: WallyDAO.xyz    ⏰ TABLE OF CONTENTS ⏰ 0:00 Introduction 0:16 Welcome 1:30 Market Movements 25:02 RWA Foundation Updates  26:51 Token Debrief 37:59 Companies of The Week

Welcome back to The Insurance Dudes! In this episode, Craig and Jason sit down with Sethe Smith, owner of the Sethe Smith Agency in Fort Wayne, Indiana, for a candid conversation packed with both wisdom and wild stories from the insurance trenches. From cleaning up unforgettable office mishaps to building a top-performing agency from scratch, Sethe shares the real-life ups and downs of agency ownership—including valuable lessons learned from failure, the importance of having a “why,” and the challenges of hiring and retaining great salespeople.Whether you're an aspiring agent, a seasoned agency owner, or just someone looking for a fresh take on what it really takes to grow a successful insurance business, this episode pulls back the curtain on the highs, the lows, and everything in between. Tune in for some laughs, plenty of actionable insights, and inspiration to tackle the daily grind with grit and vision.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Dr. Ben Derman of the University of Chicago Medicine joins the show to unpack major updates in multiple myeloma presented at ASCO and EHA 2025. He discusses the growing role of quadruple therapy across all patient populations and its implications for the future of autologous stem cell transplant, including insights from the MIDAS trial on MRD-guided transplant decisions. Additional highlights include MRD-negativity as a potential off-ramp for maintenance therapy, evolving data from frontline triplet vs. quadruplet studies, real-world referral trends, CARTITUDE-4 subgroup outcomes, and the expanding utility of bispecifics and trispecific antibodies, particularly for extramedullary disease. Check out Chadi's website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Welcome back to The Insurance Dudes! In today's episode, hosts Craig Pretzinger and Jason Feltman sit down with Tung Le, the unstoppable insurance entrepreneur behind a thriving Allstate agency in Houston, Texas. Tung gets real about his rollercoaster journey, starting from scratch in March 2020—just as the world shut down. From losing his first employees on day one, to hitting the phones himself, Tung shares how he bootstrapped his way through the uncertainty of COVID, faced painful early setbacks, and relentlessly built a powerhouse $12 million book of business in just a few years.Listen in as Tung opens up about the tough lessons learned in hiring, building a resilient team, and outlasting the storms—literally and figuratively—of the Texas insurance market. He gets candid about separating service and sales teams, dialing in on valuable data and zip codes, and learning to adapt strategies as both the industry and his agency evolve. If you've ever wondered what it takes to grow an agency from zero to millions, especially through some of the most challenging years in recent memory, this episode is packed with practical insights, plenty of laughs, and straight-shooting advice you won't want to miss. Let's jump in!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

In this episode, we dissect the phase 3 MIDAS trial in newly diagnosed transplant-eligible multiple myeloma with Dr. Meera Mohan. https://pubmed.ncbi.nlm.nih.gov/39841461/https://pubmed.ncbi.nlm.nih.gov/40459097/

Portland-based trio BELONGING have been bashing out their brand of noisy indie rock for a few years. Now part of Dipterid Records, the band is re-releasing their debut LP Hollow Cells, as well as an upcoming split with Inny.Music by:New BrutalismBelongingInnyIntro music by:Hot ZonePatreon: https://www.patreon.com/GettingitoutpodcastEmail: dan@gettingitout.netWebsite: http://gettingitout.net/Instagram: @getting_it_out_podcastFacebook: www.facebook.com/gettingitoutpodcastX: @GettingItOutPodSupport this show http://supporter.acast.com/getting-it-out. Hosted on Acast. See acast.com/privacy for more information.

Tune in to this episode of the Security Token Show where this week Herwig Konings and guest contributors, Tal Elyashiv, Managing Partner at SPiCE VC, Nico Pantelis, Partner at Blue Bay Ventures, and Jason Barraza cover the industry leading headlines and market movements, including Robinhood's tokenized stocks, stablecoin issuers like Circle and Ripple applying for bank charters, SPiCE VC's 3rd investor payout, and more RWA news!   This week Jason Barraza had a chance to sit with Yuval Rooz, Co-Founder and CEO of Digital Asset, for an inside look at their $135 million raise, the growing momentum behind Canton Network including integrating with Nasdaq Calyspo, and why privacy, composability, and real world asset tokenization as a whole are going to change global markets.  Did Yuval leave you on a cliff hanger before the RWA Foundation Updates? Jason and Yuval dive into it and more on the full interview available here: https://youtu.be/Aj4URNZo9uM    Company of the Week - Herwig: Robinhood   Companies in the news include SPiCE VC, Circle, Ripple, Robinhood, Republic, SpaceX, OpenAI, S&P Dow Jones Indices, Centrifuge, Anemoy, Janus Henderson, Midas, Fasanara, Morpho, Steakhouse Financial, Bitfinex Securities, Castle Community Bank, Arbra, Colb, Gemini, Arbitrum, Euroclear, Abu Dhabi Securities Exchange, FAB, HSBC, Bybit, xStocks, Dinari, BitGo, Spiko, Chainlink, MetaWealth, Securitize, Redstone, Apex Group, GLEIF, ERC-3643 Association, Kinexys by J.P.Morgan, S&P Global, Particula, 21X, GF Securities, Hashkey, OnRe, Lynq Network, European Central Bank, Ondo, Pantera, Zult, Stable, AMINA, Ripple, Paxos, World Liberty Financial, Plume, Paul Atkins/ SEC, SIFMA   Check Out Tal's Book “Investing in Revolutions”: https://www.amazon.com/Investing-Revolutions-Creating-Transformational-Technology/dp/B0DKS3YFWV#detailBullets_feature_div    TokenizeThis 2025 Conference Review: https://docsend.com/v/k8bn7/tt25  STM Predicts $30-50T in RWAs by 2030: https://docsend.com/view/7jx2nsjq6dsun2b9    More STM.co Reports: https://reports.stm.co/  Join the RWA Foundation and Read the Whitepaper: RWAF.xyz  Learn More About WALLY DAO: WallyDAO.xyz    ⏰ TABLE OF CONTENTS ⏰ 0:00 Introduction 0:16 Welcome 0:47 Market Movements 34:06 STS Interviews: Yuval Rooz, Digital Asset 45:23 RWA Foundation Updates 46:52 Token Debrief 58:18 Companies of The Week  

In this week's episode we'll learn more about a novel mouse model that recapitulates many of the properties of human sickle cell SC disease; results from the induction phase of the risk-adapted MIDAS trial of isatuximab, carfilzomib, lenalidomide, and dexamethasone in newly diagnosed, transplant-eligible multiple myeloma; and a link between splicing factor mutations and competitive fitness in myelodysplastic syndrome stem cells.Featured articles:A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyureaIsatuximab, carfilzomib, lenalidomide, and dexamethasone induction in newly diagnosed myeloma: analysis of the MIDAS trialCell-autonomous dysregulation of interferon signaling drives clonal expansion of SRSF2-mutant MDS stem/progenitor cells

Historierna om Minotauros och labyrinten, om Herakles tolv stordåd, om Kirke och Medea har vi hört när vi var unga, och de har lämnat outplånliga avtryck i vårt medvetande. Grekisk mytologi har inspirerat människor i tre millennier – och mer därtill – och mycket av den ingår fortfarande i allmänbildningen. Disney gör filmer om den, nya romaner skrivs, och myterna står sig fortsatt starka inom barnboksfloran.Men hur uppstod dessa berättelser? Har de sina rötter i verkliga personer och händelser? Kan vi se Minotauros‑sagan som en spegling av konflikten mellan det minoiska Kreta och de helladiska städerna i södra Grekland? Var Herakles en historisk person eller en sagofigur från sten‑ eller bronsålder? Har Atlantis funnits, eller är Platons redogörelse en moraliserande skröna? Fanns kung Midas och kung Krösus – de två rikaste monarkerna i antikens Greklands kollektiva minne – över huvud taget? Och hur förklarar vi de märkliga europeiska djuren i myterna – lejon och elefanter – har de någonsin existerat i Medelhavsområdet under antiken?I sommarreprisen av podden Harrisons dramatiska historia samtalar Dick Harrison, professor i historia vid Lunds universitet, och fackboksförfattaren Katarina Harrison Lindbergh om grekiska myter och sagor.Bild: Theseus och Minotauros. A‑sida från en attisk amfora med svartfigur, ca 540 f.Kr. Wikipedia, public domain.Klippare: Aron Schuurman Producent: Urban Lindstedt Hosted on Acast. See acast.com/privacy for more information.

Welcome to another episode of The Insurance Dudes! In this episode, Jason and Craig sit down with Cassidy Arbeli—a powerhouse agency owner whose journey is as inspiring as it is unconventional. Raised by entrepreneurial parents and equipped with a natural flair for business, Cassidy shares how she transformed her insurance career from humble beginnings with a newborn in tow to a multi-business owner, coach, and advocate for women in the industry.Cassidy opens up about the real challenges insurance agents face, from the gap in business education to the importance of building strong agency culture and the value of putting systems in place to gain real freedom. She talks candidly about what it was like to walk away from a successful captive agency to launch her own independent venture—and how that leap of faith led to even greater success and fulfillment.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Episode 21In this podcast, professional astrologers Chani Nicholas, Thea Anderson, and Eliza Robertson look to the sky to make sense of what's happening here on Earth.This episode brings you into the astrological group chat to talk through how Jupiter's long-awaited entrance into Cancer (and its recent square to Saturn) have landed IRL. Covering everything from Tina Knowles' memoir “Matriarch” and the first-ever CHANI Pop-Up to the No Kings protests, the Israel–Iran conflict, and the NYC mayoral race, we look at how the most anticipated astrology of 2025 has manifested in the collective so far. We also reflect on some of 2025's other milestone astro (hey, Pluto in Aquarius and Neptune in Aries), dig into how those transits have played out historically, and prep for what's ahead with Uranus in Gemini. These are unprecedented — yet eerily familiar — times, and we've got the charts and chats to help make sense of it all. So let's dive in.Content warning: mentions of sexual predation, genocide, murder, police brutality, and forced pregnancyTimestamps:(00:00) - Welcome to Down to Astro episode 21(00:41) - Jupiter in Cancer: An era of hope and connection(01:50) - The CHANI Pop-Up: community engagement and collective care(13:26) - The impact of the Saturn square on Jupiter's abundance(15:32) - Iran's chart and the Israel–Iran conflict(27:13) - Comparing ancient astrological predictions and current events(30:14) - The growing power of local movements with Jupiter in Cancer(32:53) - ICE protests, No Kings, and the misuse of military force(38:48) - Uranus in Gemini: Historical astrological parallels and predictions(44:27) - Neptune in Aries, NATO's chart, and redrawing international alliances(54:40) - Mars square Uranus: Israel's initial strikes on Iran(59:15) - Uranus in Gemini and the US on the brink of war(01:04:30) - The shifting world order and the need for human connection(01:07:40) - The future of intelligence, tech, and critical thinking(01:12:19) - Tina Knowles' memoir “Matriarch” and the power of art and generosity(01:18:45) - Beyoncé's Requiem for America(01:25:11) - Ask us anything: What does it mean if I'm in my Neptune square?This episode was recorded on 06/24/2025.For more astrological insights, download the CHANI app or follow CHANI on Instagram, TikTok, and Bluesky.The song “Midas,” featured in the podcast, was created by NISHA and is available wherever you listen to music.This episode also mentioned the following creative works:Ali A. Olomi's translations from Abu Mashar“Matriarch: A Memoir" by Tina KnowlesThe works of Kelly Surtees The works of Nick Dagan BestP.S. The transcript for this episode is available here.

Welcome to another episode of The Insurance Dudes! In this powerful conversation, hosts Jason Feltman and Craig Pretzinger sit down with Dan Kitajima to unpack a truly wild journey from building a $17 million captive insurance agency to making the bold leap into the independent world.Dan shares the highs and lows of his experience—from signing a jaw-dropping $20,000/month office lease just before his carrier pulled the rug out by non-renewing $6 million in policies, to learning how to pivot, retain clients, and ultimately rebuild—this time with even greater focus, flexibility, and profitability. The trio dives into the nuances of switching from captive to independent, breaking down differences in closing ratios, broker fees, marketing strategies, and what it really takes to survive (and thrive) through massive industry disruption.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

In this episode of Got Clutter? Get Organized, I'm joined by Stephanie Warlick—Founder and CEO of 5FT View Consulting—for a powerful conversation on organizing your business strategy before the year ends. Stephanie shares her journey from struggling student to business strategist with the Midas touch and reveals the five biggest “gotchas” that often derail small business owners. If you're feeling buried in decisions, details, and daily demands, this episode will help you clear the mental and operational clutter and refocus on what truly matters in Q3.

Dr. John Sweetenham and Dr. Marc Braunstein highlight top research on hematologic malignancies from the 2025 ASCO Annual Meeting, including abstracts on newly diagnosed chronic phase CML, relapsed B-cell lymphoma, and multiple myeloma. Transcript Dr. John Sweetenham: Hello, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. John Sweetenham. On today's episode, we'll be discussing promising advances in newly diagnosed chronic phase CML, relapsed B-cell lymphoma, multiple myeloma, and other hematologic malignancies that were presented at the 2025 ASCO Annual Meeting. Joining me for this discussion is Dr. Marc Braunstein, a hematologist and oncologist at the NYU Perlmutter Cancer Center. Our full disclosures are available in the transcript of this episode.  Marc, there were some great studies in the heme space at this year's Annual Meeting, and it's great to have you back on the podcast to highlight some of these advances. Dr. Marc Braunstein: Yes, I agree, John, and thank you so much for inviting me again. It's great to be here.  Dr. John Sweetenham: Let's start out with Abstract 6501. This was a study that reported on the primary endpoint results of the phase 3B ASC4START trial, which assessed asciminib versus nilotinib in newly diagnosed chronic phase CML. And the primary endpoint of this, as you know, was time to treatment discontinuation because of adverse events. Can you give us your insights into this study? Dr. Marc Braunstein: Absolutely. So, like you mentioned, you know, asciminib is an allosteric inhibitor of the BCR-ABL kinase that has activity in CML, and that includes patients with the T315I mutation that confers resistance to first- and second-generation TKIs. So, the ASC4FIRST study, which was published last year in the New England Journal of Medicine, showed superior efficacy of asciminib compared to investigator-selected first- or second-generation TKIs, actually leading to the FDA approval of asciminib in first-line CML. So, the authors of that study presented data at this year's ASCO meeting from the phase 3 ASC4START comparing safety and time to discontinuation due to adverse events of asciminib versus nilotinib, a second-generation TKI. So, 568 patients with newly diagnosed CML were randomized one-to-one to once-daily asciminib or twice-daily nilotinib. So, at a median follow-up of 9.7 months, about 11% in the asciminib group and 17% in the nilotinib group discontinued treatment, with significantly fewer discontinuations with asciminib due to adverse events. There was also a secondary endpoint of major molecular response, which was also better with asciminib. For example, the MR 4.5, which is a deep response, was 2.5% versus 0.4% favoring asciminib by week 12. So, I think in conclusion, these results build on the ASC4FIRST study, making the case for the superior safety and efficacy of asciminib versus other first- or second-generation TKIs in newly diagnosed CML. Dr. John Sweetenham: Thanks, Marc. Do you think this is going to change practice? Dr. Marc Braunstein: I think so. I think there are still some questions to be answered, such as what resistance mutations occur after first-line treatment with asciminib. But I think the sum of these studies really make the case for using asciminib upfront in CML. Dr. John Sweetenham: Okay, great. Thank you. And let's move on to our second abstract. This was Abstract 7015 and was reported from Mass General Hospital. And this was a study in patients with relapsed and refractory diffuse large B-cell lymphoma and reported the 2-year results of the so-called STARGLO study. This is a comparison of glofitamab, a T-cell engaging bispecific antibody, with gemcitabine and oxaliplatin in this group of patients. Can you tell us a little bit about your impressions of this study? Dr. Marc Braunstein: Absolutely. So just for background, the treatment landscape for relapsed/refractory large B-cell lymphoma is expanding, now with two bispecific antibodies targeting CD20 that are approved after two or more lines of therapy. Among these, glofitamab was approved in 2023 based on phase 2 data showing an objective response rate of 52%, with 39% complete responses in relapsed/refractory large B-cell lymphoma patients after a median of three prior lines of therapy. Distinguishing glofitamab from epcoritamab, the other approved bispecific, glofitamab was given for 12 cycles and then stopped. Additionally, when combined with gemcitabine and oxaliplatin in the phase 3 STARGLO study, there was significantly improved overall survival compared to rituximab plus gemcitabine and oxaliplatin in transplant-ineligible relapsed/refractory large B-cell lymphoma patients at a median follow-up of 11 months.  The authors of that study published last year in Lancet now present at ASCO this year the 2-year follow-up of the STARGLO study. Two hundred and seventy-four patients with a median of one prior line of therapy were randomized two-to-one to glofitamab plus GemOx versus rituximab plus GemOx, with the primary endpoint of overall survival. Here, the median overall survival was not reached versus 13.5 months, with a median PFS also significantly improved at about 14 months versus 4 months in the control. CRS of note in the glofitamab arm was mostly grade 1 or 2, with only about 2.3% grade 3 events. And three of the four patients had grade 1 or 2 neurotoxicity. So, John, putting this into context, I think it's encouraging that we now have randomized data showing the superiority of a bispecific plus chemotherapy over rituximab plus chemotherapy in transplant-ineligible patients. And while only 8% of the patients in the STARGLO study had prior anti-CD19 CAR T-cell therapy, I think this regimen could be considered in those patients who are ineligible for transplant or CAR T-cell therapy. Dr. John Sweetenham: Yeah, I agree. I think a couple of other compelling numbers to me were the fact that around 55% of these patients were alive at 2 years in the group who'd received glofitamab, and that almost 90% of those having that arm of the study who had a CR at the end of treatment were alive at 12 months. So, clearly, it's an active agent and also a kind of great off-the-shelf fixed-duration alternative in these relapsed and refractory patients. Dr. Marc Braunstein: I agree, and I would also note that the phase 3 SKYGLO study is looking at glofitamab plus Pola-R-CHP versus Pola-R-CHP alone. So, we may even be using these eventually in the first-line setting. Dr. John Sweetenham: Absolutely. Let's stay on the theme of diffuse large B-cell lymphoma and look at one other abstract in that space, which was Abstract 7000. This was a study from the HOVON group in the Netherlands, which looked at the prospective validation of end-of-treatment circulating tumor DNA in the context of a national randomized trial. What are your thoughts on this? Dr. Marc Braunstein: So, non-invasive liquid biopsies to detect and monitor cancers via circulating tumor-derived DNA or ctDNA, you know, is really emerging as a valuable tool in both solid and liquid tumors to understand disease biology, and also for drug development. So, to date, the most established application of ctDNA in lymphoma, I would say, is really for monitoring of minimal residual disease. So, in this correlative study by Steven Wang and colleagues in the HOVON group, they evaluated the prognostic significance of MRD status as assessed by ctDNA following first-line treatment with curative intent with either R-CHOP or dose-adjusted R-EPOCH. At the end of treatment, encouragingly, 76% of patients were MRD-negative, and 24% were MRD-positive. Now, of note, MRD-positive status at the end of treatment predicted inferior progression-free survival at 2 years, with only 28% of patients who are MRD-positive being progression-free versus 88% who are MRD-negative. And in fact, all the patients who failed to achieve a complete response after first-line treatment and were MRD-positive ultimately relapsed. So, circulating tumor cells are rarely found in large B-cell lymphomas, and so this study really builds on accumulating data that ctDNA has clinical value to detect residual disease with a non-invasive approach. So, there are many implications of how we could potentially use this to detect early signs of relapse, to potentially escalate treatment for consolidation if patients remain MRD-positive. So, I think this will eventually become utilized in clinical practice. Dr. John Sweetenham: Yeah, I agree. I think it's interesting that it provided an independent assessment of response, which was independent, in fact, of the results of PET-CT scanning and so on, which I think was very interesting to me. And the authors of the abstract actually commented in their presentation that they think this should be integrated as part of the standard response assessment now for patients with large B-cell lymphoma. Would you agree with that? Dr. Marc Braunstein: I would. For one thing, it allows repeated sampling. It's a non-invasive approach; it doesn't necessarily require a bone marrow biopsy, and it may have more sensitivity than conventional response measures. So, I think having a standardized system to assess ctDNA will be helpful, and definitely, I think this will be a valuable biomarker of disease response. Dr. John Sweetenham: Okay, great. Thanks. We're going to change gear again now, and we're going to highlight two abstracts in the multiple myeloma space. The first one of these is Abstract 7507. And this abstract reported on the long-term results of the CARTITUDE study for patients with relapsed and refractory multiple myeloma. What are your comments on this presentation? Dr. Marc Braunstein: So, this study actually got a lot of press, and I've already had multiple patients asking me about CAR T-cells as a result. Just as some background, CAR T-cells targeting BCMA, which is pretty much universally expressed on malignant plasma cells in myeloma, have really shown remarkable responses, especially in heavily pretreated patients, showing superior progression-free survival in both later and earlier phases of the disease, including in randomized studies in patients with second-line or beyond. So, the CARTITUDE-1 was really the original Phase 1/2 study of ciltacabtagene autoleucel, one of the two approved anti-BCMA CAR T-cell products, which was investigated in patients with a median of six to seven prior lines of therapy. So, these were patients who were pretty heavily pretreated. So, in the study presented by Voorhees at this year's ASCO meeting, this was the long-term follow-up at a median of 5 years from the one-time CAR infusion in these patients with a median of five prior lines of therapy. And remarkably, of the 97 patients, 33% remained progression-free at 5 years plus, without needing any further myeloma treatment during that time. And among those 33% of patients, 23% had high-risk cytogenetics, which we know are notoriously difficult to achieve responses in. What was interesting that they presented as correlative studies was there were some biomarkers that were distinguishing the patients who had the long PFS, including enrichment of more naive T-cells in the product, lower neutrophil-to-T-cell ratio, higher hemoglobin and platelets at baseline, and higher CAR T-cell levels relative to soluble BCMA levels. And the fact that they reported a median overall survival of 61 months in these really heavily pretreated patients, I think these data are impressive. I think we're going to continue to be using CAR T even earlier in the disease status than fifth or sixth line, as it was studied in CARTITUDE-1. There are even ongoing studies looking at first-line treatment with CAR T-cells. Dr. John Sweetenham: So, do you think that those 33% of patients who are disease-free at 5 years, do you think any of those are cured?  Dr. Marc Braunstein: That was one of the headlines in the press. I think if we're going to discuss things like "operational cures," where we're transforming myeloma into really a chronic disease, where patients can live practically a normal life expectancy, I think the measure of 5 years, especially in this population that was explored in CARTITUDE-1, I think we can call that close to a cure. Dr. John Sweetenham: Okay. Well, thank you. Exciting data, for sure. We're going to conclude today with another abstract in the multiple myeloma space. And this was Abstract 7500, which looked at an MRD, minimal residual disease-driven strategy following induction and transplant-eligible newly diagnosed multiple myeloma patients and reported on the primary endpoints of the phase 3 MIDAS trial. Can you walk us through this one, Marc? Dr. Marc Braunstein: Absolutely. It is a bit more complicated than the prior one we discussed because this is a randomized study with four arms. So, I'll start by saying that anti-CD38-based quadruplet regimens continue to show superior outcomes in both transplant-eligible and -ineligible newly diagnosed multiple myeloma patients. The MIDAS study mentioned is an open-label phase 3 trial with four arms in transplant-eligible newly diagnosed myeloma patients.  And initially, these patients were all treated with quadruplet therapy with the anti-CD38 antibody isatuximab combined with carfilzomib, lenalidomide, and dexamethasone in 718 newly diagnosed myeloma patients. So, they received the quadruplet regimen for six cycles and then were randomized based on their MRD status at 10 to the negative fifth following six cycles of induction. And that first randomization, if they were MRD-negative, was to either consolidation with six more cycles of the quadruplet regimen or transplant, autologous transplant, plus two cycles additionally of the quadruplet regimen. And both arms were followed by lenalidomide maintenance. The primary endpoint was MRD negativity at 10 to the negative sixth prior to entering the lenalidomide maintenance component. And in addition, the patients who were MRD-positive after induction were randomized to transplant plus two cycles of consolidation or a tandem autologous transplant. So, the median follow-up of the study was about 16 months, and the pre-maintenance rate of MRD negativity was high, between 84 to 86% between the two arms who were MRD-negative, which was not significantly different. And as far as the 233 patients who were MRD-positive, the pre-maintenance MRD negativity was also not significantly different at 40% for those who received autologous transplant, and 32% who received a tandem transplant. So, there's a lot of debate in the myeloma field about the evolving role of autologous transplant and whether transplant still plays a significant role in patients who are either MRD-negative after induction or who have deep remissions and are of standard risk. So, I think these data suggest that patients who are MRD-negative after induction with a quadruplet regimen studied here, which was Isa-KRd, plus consolidation, may possibly be able to forego consolidation with autologous transplant. And likewise, for those patients who are MRD-positive after induction, tandem transplant didn't seem to provide much of a benefit compared to single transplant, which is consistent with prior studies such as the StaMINA study. Dr. John Sweetenham: So, where do you think this leaves us, Marc? Are we going to need more studies before we have any definitive guidance on whether an autologous transplant is still appropriate for those patients who are MRD-negative? Dr. Marc Braunstein: Well, as clinicians, we want to do what's best for our patient. And in myeloma, the best we can do is to get as deep remissions as possible, meaning MRD negativity. And so, I think it's clear from the MIDAS study and others that quadruplet regimens provide the deepest remissions when given upfront. We can debate the role of autologous transplant. I think certainly the role of tandem autologous transplant is fading. But as far as a single autologous transplant as consolidation, I think it's reasonable as a goal to try to achieve MRD negativity after the transplant, especially for patients who remain MRD-positive after induction. Dr. John Sweetenham: Okay, great. Marc, thanks as always for sharing your insights on the heme malignancies studies from the ASCO meeting this year and for joining us on the ASCO Daily News Podcast. Always appreciate hearing your thoughtful and balanced input on these. Dr. Marc Braunstein: My pleasure. Thank you, John. Dr. John Sweetenham: And thank you to our listeners for joining us today. You'll find links to the abstracts discussed today in the transcript of this episode. Finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts.   Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.  Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.   Find out more about today's guest:  Dr. John Sweetenham Dr. Marc Braunstein   @docbraunstein     Follow ASCO on social media:   @ASCO on Twitter  ASCO on Bluesky  ASCO on Facebook   ASCO on LinkedIn     Disclosures:  Dr. John Sweetenham:  Consulting or Advisory Role: EMA Wellness  Dr. Marc Braunstein:  Consulting or Advisory Role: Pfizer, Bristol-Myers Squibb/Celgene, Adaptive Biotechnologies, GlaxoSmithKline, ADC Therapeutics, Janssen Oncology, Abbvie, Guidepoint Global, Epizyme, Sanofi, CTI BioPharma Corp  Speakers' Bureau: Janssen Oncology  Research Funding (Institution): Janssen, Celgene/BMS

The Bulletproof Dental Podcast Episode 399 HOSTS: Dr. Peter Boulden and Dr. Craig Spodak GUEST: Amir Mansouri, SprintRay DESCRIPTION In this episode of the Bulletproof Dental Practice Podcast, Dr. Amir Mansouri, co-founder of SprintRay, shares his journey into 3D dental printing and discusses how this technology is transforming dental practices. The conversation covers the evolution of dental technology, the importance of patient experience, and why practices must adopt 3D printing to stay competitive. Dr. Mansouri also explores the integration of AI in dental design, the role of empowering dental staff, and how these innovations are improving patient care through same-day solutions. TAKEAWAYS SprintRay simplifies 3D printing for dental practices, with Dr. Mansouri's engineering background driving innovation Over 60% of dental practices now use digital solutions like intraoral scanners Night guards are the ideal starting point for practices new to 3D printing Material science challenges are being addressed through Sprint Ray's high ceramic content MIDAS technology The future will see coexistence of milling and printing, with same-day dentistry favoring 3D solutions Entry-level 3D printers now cost around $10,000, while ovens range $10,000-$15,000 AI is simplifying dental design processes and empowering dental assistants Same-day restorations improve patient care and reduce temporary retention issues User-friendly technology is essential for successful staff implementation The dental industry thrives on collaboration and continuous innovation CHAPTERS 00:00 Introduction to Dr. Amir Mansouri and SprintRay 02:01 The Journey into 3D Dental Printing 10:08 Progression of 3D Printing Applications 11:48 The Importance of Patient Experience 13:05 Current State of 3D-Printed Restorations 16:05 Advancements in Material Science 20:52 The Future of 3D Printing in Dentistry 29:10 Understanding the Cost of Dental Technology 35:05 3D Printing in Dentistry: Accessibility and Cost 37:04 The Role of AI in Dental Design 39:55 Empowering Dental Assistants with Technology 44:01 The Future of Dentistry: Innovation and Collaboration   REFERENCES Bulletproof Summit Bulletproof Mastermind

On this episode of The Insurance Dudes, hosts Craig Pretzinger and Jason Feltman sit down with BJ Hill, owner of Summit Insurance in Loveland, Colorado. BJ shares his remarkable journey from college basketball coach to building one of the top insurance agencies in the country, now writing over $18 million in premium. From his early days as a “juco” coach and experiencing a steep learning curve buying his first $3 million agency, to overcoming challenges like passing industry exams and developing his leadership style, BJ gets candid about the grind, the setbacks, and the drive required to scale a business.Tune in as BJ reveals the secrets to coaching and developing a winning insurance team, the importance of culture and accountability, and the lessons he's learned from both sports and entrepreneurship. His unique perspective shows how building champions—on the court or in the agency—always comes down to grit, self-awareness, and relentless improvement. Plus, you'll hear some wild agency stories, tactics for onboarding and motivating staff, and BJ's best advice for fellow agency owners who want to scale up. Get ready for an inspiring, actionable conversation, packed with real-world insights for insurance pros and business leaders alike!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Quique seeks answers. Midas seeks retribution. Content Notes: Fire SFX, Explosion SFX, Phone Ring SFX, Hallie yelling a lot Character List: docs.google.com/document/d/1QLtdBJBznVKM9dUkPs_Z1JemAulyK96WIm5xBr7W0jU/edit?usp=sharing Follow Quest Friends! online Website: ⁠⁠⁠questfriendspodcast.com⁠⁠⁠  Patreon: ⁠⁠⁠patreon.com/questfriends⁠⁠⁠ Everything else: ⁠⁠⁠linktr.ee/questfriendspodcast⁠⁠ Music Credits "Quest Friends! Hereafter Theme" by Miles Morkri: ⁠⁠⁠twitter.com/milesmorkri⁠⁠⁠ "Spooky Halloween Night Cut D" by AdiGoldstein: ⁠⁠⁠pond5.com/royalty-free-music/item/75369121-spooky-halloween-night-cut-d⁠⁠ Additional Music from Motion Array: ⁠⁠⁠motionarray.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome to another exciting episode of The Insurance Dudes Podcast! Today, we have a special guest, Brian Ahearn. With his extensive experience in the insurance industry and expertise in the psychology of persuasion, Brian shares invaluable insights that can help transform your agency operations and enhance your sales skills. From the importance of building genuine relationships to leveraging principles of psychology in everyday interactions, Brian offers a wealth of knowledge that is sure to elevate your professional game.Whether you're a seasoned agent or new to the industry, you won't want to miss this enlightening conversation packed with tips and strategies to create a more predictable and profitable agency. Tune in for this engaging discussion that dives deep into understanding human behavior, client interactions, and the art of persuasive selling.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Welcome to another exciting episode of "The Insurance Dudes," where hosts Craig Pretzinger and Jason Feltman are on a mission to help you escape the constraints of your insurance agency with the secrets to creating a predictable and profitable sales machine. In this episode titled "Audio Make Leads Paid For Put Your Thimble On Front Of Funnel," we have a fascinating guest, Jay Bregman, who takes us on his entrepreneurial journey in the insurance industry.Jay shares how his passion for drone piloting unexpectedly led him to identify a gap in the market—drone pilots struggling to secure insurance for their gigs. This revelation sparked the creation of Thimble, a company dedicated to simplifying the world of small business insurance. Jay delves into the nuances of building his team and the challenges of sticking to a disciplined business model as they expanded from insuring drone pilots to servicing a myriad of small business professionals with a modern approach.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Welcome to another exciting episode of "The Insurance Dudes," where hosts Craig Pretzinger and Jason Feltman are on a mission to help you escape the constraints of your insurance agency with the secrets to creating a predictable and profitable sales machine. In this episode titled "Audio Make Leads Paid For Put Your Thimble On Front Of Funnel," we have a fascinating guest, Jay Bregman, who takes us on his entrepreneurial journey in the insurance industry.Throughout the episode, Jay offers invaluable insights for insurance agents and entrepreneurs alike, emphasizing the importance of adaptability and endurance in an ever-evolving industry. He highlights the advantages of embracing new technologies early on to stay ahead of the curve and maximize opportunities. Don't miss this engaging conversation packed with practical advice on how you can leverage insurtech innovations to transform your own agency. Grab your notepads, and let's dive into the world of insurance with the always inspiring Jay Bregman!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Welcome back to another exciting episode of The Insurance Dudes! Today's guest is none other than Dave Williams, a dynamic entrepreneur with a fascinating journey from overcoming personal and professional challenges to building a multi-million dollar insurance agency. Dave shares his insights on the importance of mastering your craft from the ground up, the power of cultivating a positive company culture, and the transformative effects of focusing on health and well-being. We dive deep into his process of scaling an insurance business through effective sales funnels, innovative hiring practices, and maintaining a strong growth mindset.Whether you're an agency owner or aspiring entrepreneur, this episode is packed with valuable lessons and inspiration to fuel your path to success. So, get ready as we hit the ground running with Recruit King Dave Williams, only on The Insurance Dudes!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Welcome back to The Insurance Dudes! In this episode, hosts Jason Feldman and Craig Pretzinger sit down with industry powerhouse Peter Fournier to uncover the secrets behind building a thriving, recession-proof insurance agency. Peter shares his journey from flipping Pokémon cards as a kid to carving out his niche in mortgage protection within the insurance world. He dishes out hard-earned lessons on money management, the critical importance of process, and how mastering referrals transformed his business. You'll get candid stories from the field, tips on holding yourself accountable, and actionable advice for new and seasoned agents alike.Whether you're looking to break free from the grind of cold leads or level up your agency sales game, there's a ton of wisdom packed into this lively and insightful conversation. So grab your notepad, and let's dive in!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

In this episode of The Insurance Dudes, hosts Craig Pretzinger and Jason Feldman sit down with Wild Bill Rice to explore the ins and outs of lead generation within the insurance industry. As a seasoned professional in marketing and lead generation, Bill Rice offers valuable insights into understanding the unique challenges and opportunities tied to insurance leads. They delve into effective strategies for engaging potential clients, the importance of nurturing leads, and the role of persistence and adaptability in today's market.Whether you're a new agent looking to build your book of business or a seasoned pro seeking fresh perspectives, this episode is packed with actionable advice that can help you elevate your sales game. Join us as we discover the secrets to transforming leads into loyal customers, and learn how insurance agents can harness the power of effective marketing techniques to drive success in their agencies.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

In this exciting episode of The Insurance Dudes, join hosts Craig and Jason as they bring in the dynamic Jas Takhar live from his own studio. Known for his high-energy approach, Jas promises to match and potentially exceed the enthusiastic vibes. Dive into a lively conversation filled with rapid-fire questions and insightful discussions on content creation, real estate sales, and the impact of personal branding in business. Jas shares his journey from being labeled a little narcissistic to becoming a prolific content creator and successful real estate agent. Learn how building a personal media squad transformed his business and why staying true to your passion is key in any industry.Whether you're an insurance agent or a budding entrepreneur, this episode brims with actionable advice and motivational insights to revitalize your career and inspire your entrepreneurial spirit. Tune in and get ready for some high-energy exchanges and valuable takeaways from The Insurance Dudes and their engaging guest, Jas Takhar!Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

In this episode of The Insurance Dudes, join hosts Craig Pretzinger and Jason as they dive into an insightful conversation with Sales Coach and Speaker, Rob Liano. Growing up as the youngest of four boys with a father who transitioned from engineering to excelling in vacuum sales, Rob learned early on about the power of sales and determination. From his beginnings as a rock drummer to becoming a renowned sales trainer, Rob shares his journey of overcoming financial hardships and rediscovering the potential of sales as a career path.Discover the importance of customer-centric sales approaches, the necessity of continuous learning, and embracing technology to enhance business practices. This episode is filled with valuable lessons for sales professionals and entrepreneurs alike, making it a must-listen for those looking to elevate their sales strategies in 2021 and beyond.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

In this episode of The Insurance Dudes, hosts Craig and Jason sit down with Patrick Albrecht, President of Associated Insurance Administrators (AIA), to discuss the evolution of commercial insurance marketing and sales. Patrick shares his journey from Air Force engineer to insurance executive, offering valuable insights into the wholesale insurance business.Learn about effective niches in commercial insurance, including healthcare, municipalities, and forestry products. Patrick discusses how the insurance industry has transformed from door-to-door sales to modern data-driven approaches, while emphasizing that relationships remain key to success.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Welcome to this episode of The Insurance Dudes, where hosts Jason and Craig sit down for a high-energy, no-holds-barred conversation with the dynamic David Carothers.David shares his unconventional journey from a college baseball player and retail worker living off macaroni and cheese to running a powerhouse commercial insurance agency in Tampa. In this episode, you'll hear how David's unique hiring process—bringing in producers from outside the insurance industry—and his out-of-the-box, yet structured approach have set his agency apart. He talks candidly about building a resilient culture, the importance of self-belief, and getting creative within the strict confines of insurance regulations. With plenty of laughs, practical advice, and raw insights, David lays out exactly what it takes to thrive in this business, even when the odds—and your bank account—are stacked against you.Whether you're new to insurance or a seasoned pro, this episode is packed with the energy and wisdom you need to go out and get it.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

On this episode of The Insurance Dudes, Jason and Craig sit down with David Kelly, the author who literally wrote the book on incentive compensation management and the founder of insuretech startup BobTrack. David shares his unconventional journey into the insurance industry—starting as a complete outsider who's never sold a policy but knows how to turn tangled insurance data into actionable insights. We delve into the legacy technology challenges facing carriers and agencies, from mainframes that are older than most agents to the complexities of integrating new software.David reveals how his solutions help agencies not only forecast and reconcile commissions, but also gain a clearer picture of their book of business by integrating with existing agency management systems. The conversation also peels back the curtain on why incentive comp is such a headache for insurers, and how better data tracking can uncover missing commissions and streamline agency finances.Join the elite ranks of P&C agents. Sign up for Agent Elite today and get exclusive resources to grow your agency!

Got thoughts, feedback, or questions? We'd love to hear from you—send us an email.In this episode of The Art of Letting Go, I'm joined by my friend and collaborator DDM (aka Manny), a genre-defying artist who's built his own creative universe rooted in authenticity, boldness, and evolution. We talk about his journey from battle rap to redefining queer artistry in hip-hop, navigating identity, and what it means to measure success on your own terms.I also reflect on my return to the basketball court at a recent gay tournament, what it taught me about presence and self-acceptance, and why we have to meet ourselves where we are.This episode is for anyone learning to own their story—on the court, on the mic, and in life.

Episode 20In this podcast, professional astrologers Chani Nicholas, Thea Anderson, and Eliza Robertson look to the sky to make sense of what's happening here on Earth.This episode brings you into the astrological group chat to talk through how the Full Moon in Scorpio, the Uranus cazimi, and Jupiter's square to the lunar nodes have manifested IRL. We get into everything from the Democratic cover-up of Joe Biden's decline to the start of the Diddy trial, the fire at a 166-year-old plantation, and the selection of the new Pope — then we break down how these key astrological events have shown up in the collective. We also look ahead to Saturn's shift into Aries and unpack what that transit means for anyone entering a Saturn return, or any other significant Saturn transit. We rant. We reflect. We keep it real. There's a lot to get to, so let's get going.Content warning: sex trafficking, sexual assault, genocide, slavery, murder, wildfiresTimestamps:(00:00) - Welcome to Down to Astro episode 20(08:56) - Personal stories from the Scorpio Full Moon(15:00) - Political reflections: Joe Biden's Scorpio stellium(21:00) - The Diddy trial: uncovering dark secrets(26:56) - Cassie's case and the Mars Synodic Cycle(36:44) - Historical parallels: Anita Hill and Cassie(38:16) - Mars cazimi, 1991 and now: South Africa in the news(42:22) - The Full Moon and high-profile trials(44:48) - The importance of centering survivors(48:08) - Saturn, Ceres, and Cassie on the stand(50:42) -  Burning down the past: Neptune and the Nottoway Plantation fire(57:39) - The Scorpio Moon, the Mars–Pluto opposition, and global politics(01:07:39) - Power outages, tech failures, and the Uranus cazimi(01:14:04) - The significance of Jupiter's square to the nodes of the Moon(01:18:21) - Jupiter, ChatGPT, and the impact of tech in higher education(01:22:44) - The astrology of Pope Leo XIV(01:30:45) - Saturn's shift into Aries(01:37:40) - Navigating your second Saturn return(01:39:45) - Saturn squares: key Saturn transits in your 30s and 40s(01:41:09) - Upcoming astrological shifts: Saturn in Aries and Jupiter in CancerThis episode was recorded on 5/20/2025.For more astrological insights, download the CHANI app or follow CHANI on Instagram, TikTok, and Bluesky.The song “Midas,” featured in the podcast, was created by NISHA and is available wherever you listen to music.This episode also mentioned the following creative works:Original Sin: President Biden's Decline, Its Cover-Up, and His Disastrous Choice to Run Again by Jake Tapper and Alex ThompsonWe Do Not Care Club series on TikTok by @justbeingmelaniDoppelganger by Naomi KleinP.S. The transcript for this episode is available here.