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Und schwupps, ist es da, das neue Jahr! FDAs ging irgendwie ganz schnell, oder? Silvester verbringen wir dabei ganz unterschiedlich, aber beide ruhig und ohne Wachsgießen. Aber dafür mit viel leckerem Essen und hoffentlich ohne viel geböller (Böllerverbot wann??) Das Theme der Woche sind dieses mal unser Vorsätze für das neue Jahr, ist ja klar. Dabei geht es weniger um „4929 mal ins Fitnessstudio gehen“ sondern eher in Richtung „regelmäßig Sport treiben“, damit es auch machbar bleibt. ´ BUCHEMPFEHLUNGEN: Haben beide keinen, sorry ERWÄHNUNGEN: Folge 140 „Uns reicht's! Böllerverbot wann?!?“ - https://open.spotify.com/episode/0lNIgWLKoS7orHD3EqY7Xv?si=69a3511ba62e4d05 HIER FINDET IHR UNS: Spotify Bewertung - https://tinyurl.com/24voda5d Apple Bewertung - https://apple.co/2NX1rBW YouTube Kanal - https://tinyurl.com/277fkhcm Buchempfehlungen - https://bit.ly/2Z7wb9r Musik-Playlist - https://tinyurl.com/2cnd34jq Kat - https://instagram.com/katcomatose Zora - https://instagram.com/ichbinszora Email-Kontakt: londoncallingpodcast (at) googlemail (dot) com *Affiliate Link (Thalia)
Tiff and Dana discuss the ideal ways to utilize expanded functions dental assistants (EFDAs). They provide different ideas of how an EFDA can effectively fill in gaps, address scheduling SNAFUs, why state regulations need to be taken into consideration, and more. Episode resources: Reach out to Tiff and Dana Tune Into DAT's Monthly Webinar Practice Momentum Group Consulting Subscribe to The Dental A-Team podcast Become Dental A-Team Platinum! Review the podcast Transcript: The Dental A Team (00:01.464) Hello, Dental A Team listeners. We are back at you. Dana and I, Dana, thank you for being here with me today. I'm so excited to see you. How are you on this lovely, lovely, still morning? Yes, morning. Dana (00:14.474) God, I'm doing pretty good. I'm excited to be here. I like this. I know you're always like, I love my time with Dana. It's equally reciprocated. So I'm excited to get a little extra Tiff time today. The Dental A Team (00:21.101) Thank you. Thank you, me too, me too. We really need to, I was thinking this morning, as I was getting ready for work, I was like, my gosh, we need to schedule the Seven Falls hike in Tucson because it's getting cooler, we'll say. So yeah, we need to find a weekend that we can get down there, you can get up there, and we meet, it's almost in the middle, right? So, awesome. Okay, hiking is my jam, you know that, we'll get that scheduled and... Dana (00:42.731) Yes. The Dental A Team (00:49.771) We're going to spend some time together today. We've already recorded one podcast and I cannot wait for that one to release. I think it was fantastic. Doctors. was really good. We just did it about coding and making sure that systems are accurate and billing is accurate and billing representatives, making sure that you're getting the support you need from your doctors within that coding accuracy department. So go listen to that. If you haven't listened to it yet, I do love all of our podcasts. I think that they're all fantastic, but We like to hear it from you guys too. So whatever you think, whatever you need, if there's ever ideas that you guys have too that you're like, gosh, I would love more information about this. Do you know anything? One, ask us at Hello@TheDentalATeam.com We're always here to help answer questions or give ideas. But if you've got podcast ideas, like we are open to them. literally, the consulting team goes through and we pick the topics and we try to think of the things that you might like. And I honestly think sometimes we might miss the mark on something. So. Let us know if there's things that you want more information on or things that we could dive into further for you, because we're here for that. Also drop a five star review. Let us know what you think down there as well, because we do love hearing about it. I love sharing podcasts, Do you ever share a podcast with your friends? I have a very specific friend group that's podcasters, and we very specific podcasts that we share. Do you have one of those in your life? Dana (02:10.75) Yes, I do. And I always joke around and say, if I start sending you podcasts or even sometimes like funny Instagram things, like you've made it to my inner circle. The Dental A Team (02:18.672) Yeah, I totally agree. I saw a the other day that was like, it's a full-time job. I'm here for it. You're welcome. And it was like sending memes all day to my best friend or something like that. And my best friend is a stay at home mom. And so I sent it straight to her. She's like, You're welcome. I'm gonna log on at the end of the day and I'm like, my gosh, got a lot of things in here. Yeah, but I do, I love sharing the podcasts and sometimes I'll share a podcast and they're like, gosh, I can re-listen to this. I'm like, I don't know. Like sometimes I just re-listen to podcasts and I get nuggets and tips that I didn't catch before or it hits a little bit differently. And I know I've gone back and listened to years later a podcast and been like, wow. I didn't even realize it could have meant this or now I'm in this space of my life and it's completely applicable. And I think about that on my free time, I listen to much different, I listen to leadership and life coaching style podcasts and I do sprinkle some dentistry in there just to stay up to date. But it made me think this morning too, these podcasts that we do. Sometimes we've got startup doctors or two years into owning the practice or associate doctors who maybe don't own their own practice yet or maybe they don't want to own their own practice but they're super new, listen to a podcast and then fast forward five years, we've been doing this podcast for a long time you guys, going back and listening to it from a different perspective. Today I'm a different person than I was five years ago when I first listened to it. It made me think about that this morning. I love podcasting, I love pulling you guys into the podcasting world and getting this time with you. And it really made me think about how different stages of your life things are just gonna hit a little bit differently. So I wanted to take that minute to just remind everyone to go back through. We've got a million podcasts. Share with your friends, share with your family who's in dentistry. Like how many of us, right, have some sort of family member who's also in dentistry that could use the information? The Dental A Team (04:19.771) Just a quick reminder, and today's topic is super fun. I am not an EFDA. I will put that out there. I'm not an EFDA, but I'm a dental assistant at heart. I will say it every single time. I just said it on the last podcast. I love dental assisting. It just makes me so happy. It fulfills my soul. So today, Dana, I thought it would be really fun to take a little adventure down the road of what an expanded functions. dental assistant within a practice might look like. And I think this is a good space for teams and for doctors, a good podcast for doctors to really get some ideas on what that could look like within their practice. Now doctors, will say and listeners out there, not every state sees an EFDA for what another state sees them as. So a lot of the things that we're going to talk about, remember we consult practices from coast to coast. We are all over the country. And so we've got tidbits and pieces that we picked up from different practices all over different states. So caveat to today, I want you to go check what your state's requirements are, what your state's legalities are, what they can or can't do before taking anything we say and implementing it right off the bat, right off the bat, unless you already have that information. Really easy place to go is your state dental board. ADA usually has some interesting facts on per state. So just go double check those beforehand. So that's my caveat, but Dana and I both have worked with a lot of practices who do utilize EFTAs. It's a wild wild west out here, so we don't require the EFDA, but we do have that available here and you can do more with it. You can do the coronal polishing and things like that here in Arizona, but it's... sadly not yet required in Arizona. I think it is getting pushed towards that way. But I wanted to pick your brain a little bit Dana on some things that you've seen maybe just within different practices across the country. We don't have to like state specific them or anything, but how have you seen chair, know, chair side wise with a doctor and after really be useful to the dentist and the practice for maybe even practice flow. Dana (06:29.374) Yeah, so I there's two ways that I think are super common. And I do think that, like knowing, like you said, knowing your state regulations, exactly what you're after can and can't do will kind of help you choose which way might work best for your practice. And there is the first way is they really have their own column, right? And the doctors hop in where doctor is needed. And then the flip side of that is there isn't a separate column for them. They just follow the doctor. So I think it just kind of depends on how much they can do independently based on state laws as far as which one you choose. But those are the two most common structures that I see. And I think that... Again, we wanna maximize the way that we utilize them. The other thing that I see is EFTAs being used a lot for assisted hygiene because if they can coronal polish, that's just another avenue for them to be able to help in a different way, help to boost production too and just see more patients. The Dental A Team (07:19.283) Yeah, thank you. The Dental A Team (07:29.703) Yeah, I agree with that. I was thinking the same thing with hygiene and I was actually thinking as you were talking about like their own provider column or utilizing that provider situation where the doctor's kind of almost the assistant following the assistant, right? It makes me think of your hygiene schedule because if you've got an assisted hygiene schedule or even just two or more hygienists, your doctors are going in for what they need to for their exams. So it's kind of similar I think to... practices and team members get a little hung up on the scheduling piece and like wrapping their minds around it because you're kind of like Reworking how you thought about an appointment you learned how to schedule an appointment you learn the X's and slashes and the block scheduling but now we're like totally warping what you knew and adding a new caveat but if you think of it in that like assisted hygiene or Double or triple hygiene where the doctors coming in for the exams. It's kind of similar the doctors coming in for their pieces, right, for the drilling and the decay removal while the assistant stays there just like the hygienist would stay there and finish the cleaning, et cetera, the assistant staying there and filling the tooth back in and finishing it out. So the doctor would come and go and follow the assistant more as a provider. So I do have, I actually have an interesting like smash of all of that information. I do have a practice in a state in Tennessee. that she's a fantastic dentist and she has like these insanely great ideas and she's always smashing things together. She actually took a hygienist, had a hygienist EFDA. So she had a hygienist go get her EFDA and now she truly is like a provider column because she's doing hygiene and she's doing EFDA out of that column, out of her chair in her room. So it's kind of cool because when practices do that, I have a few practices that are maybe not hygienists, but doing that kind of column in that chair, that process for like a provider of a few offices that are doing that. And it's almost like you can then look at it as you would an associate or that fifth hygiene. Like how much is this column, how much is this chair able to produce based on what my UFDA can produce and not just what my doctor. So then my doctor column, like my doctor heavy column over here can be those big long. The Dental A Team (09:46.101) crown appointments or root canals or whatever. And while he or she is able to break and go do what they need to do in my assistant, my EFDA column, they go pop over and do that and my EFDA finishes it. It's almost as if my EFDA is a provider there and can provide that column's worth of production. So it really helps you, think, when you do it that way to be able to split it out very easily. And then Dana, you mentioned the assistant following the doctor. that's kind of the same as it is now, but you would need that other assistant to be there if the other one, like you've got two assistants calling the doctor, but that one makes it, that one I think is probably the easiest version for the scheduling aspect for people to digest because it's more similar to the way we naturally already learned how to schedule. So I think that's probably the most common one that we see. Dana (10:22.368) there. The Dental A Team (10:41.62) And then the hygiene one, I love that, the assisted hygiene, because yeah, coronal polishing, most of them can coronal polish and most states allow that, but again, double check that for you. But I do, actually have a practice that seriously struggles with hygienists. Like they're just in an area that is impossible to get and keep a hygienist. It is so hard. So what they've done is they've actually completely changed the model of their practice and we're still testing it. We're only a few months in, so do not drop everything and change everything unless you have already been on this train and you're ready for it, but I'm not suggesting you drop everything and change it. Hygiene is difficult right now. I will put that out there. And we need more hygienists, so everyone out there listening, if you wanted to be a hygienist, go be a hygienist. need more of you guys. But this practice is really struggling in their hygiene department, so what they did was they actually got rid of the normal hygiene model, and the doctor is the hygienist and the doctor, but he's got his FDES who are running the hygiene schedule. So he'll actually have like full hygiene only schedule and he'll run three or four columns of just hygiene. And it's actually super similar to a pedo practice scheduling. So there are smaller appointments and the assistants are doing most everything. He goes in and scales and does the exam at the same time. And he pops out and he's just running around like a pedo doctor would from room to room doing the scaling and the exam. So that's actually been super beneficial for their practice because then they'll do three days of hygiene, two days of heavy treatment because they've got now four assistants. And so they can run assistant-driven columns on treatment days. And then his column, he can run two chairs on his with two assistants and then two assistant-driven columns. where his F-Dos can be over there doing whitening, they can do impressions or scans for night guards, all of those pieces. So smashing all of those worlds together, he is exhausted, I'm not gonna lie. He's still trying to figure it out, because he's running around like a chicken. But it is a kind of cool smash between that Peto style of scheduling and then going back to that GP style of scheduling for those F-Dos. The Dental A Team (13:00.019) I know you have lot, have practices spread out all over the place too. What have you seen practices doing? Those were kind of like examples, even similarly, but what have you seen in your practices, them really be able to utilize those F-DOS4 within all of their treatment? Dana (13:03.21) Yeah. Dana (13:15.86) Yeah, I love that you pointed out, Pito, because that is a great space to utilize an EFDA because assistants are doing a lot of the hygiene, but when the assistant can do the sealants and do the night guards and even do some of the restorative, you know. The Dental A Team (13:25.984) Yeah. Dana (13:30.812) after the preps are done, jump in and do that. So, PETO is a great avenue where you can really maximize an EFDA. So, if you're a PETO practice, consider at least having one EFDA on your clinical team because you really can maximize what they can do, especially, I mean, kiddos were trying to crank and burn out those sealants pretty routinely on those kiddos. And so, having an EFDA that even they can be scheduled specifically in their column for that, that's a really great way to maximize it. I do agree on those power hygiene days. I've got a lot of practices that are doing the same thing where it's a power hygiene day. We are bringing in as many hygienists or assistants as we can and doctor and team are cranking out as much as you can there. And I like the assisted hygiene model and even if you're not in pedo, right, to be able to have them say, hey, no, let's go in overflow. Let's do your whitening today. Hey, no, let's go into overflow. Let's get that night card started. Like they can maximize and expand on what's already on a hygiene column. And if you're just a practice where like your restorative side The Dental A Team (14:14.005) You too. Dana (14:30.668) is busy and you are booked out so far, consider bringing in an EFDA who can run their own, like essentially have their own column that you hop in and out of while you're seeing your patients to really be able to maximize the restorative need in your patient base. The Dental A Team (14:44.576) Yeah, absolutely. I love that you said that about pedo with like the sealants and things, because I was actually in one of my favorite practices not that long ago out in Atlanta. She's a pedo dentist and it is just like, I love pedo practices. I just get so, I feel like a child when I'm there and like, my gosh, I'm so excited. And it's so much fun, but it's moving so quickly. And the front office gals, the scheduling, they slid in like. some sealants on a hygiene day, right? Which is like a no-no in this practice and in PETO, like if it's a hygiene day, it's fricking hygiene. And if you're not, don't have F-dos or hygiene doing the hygiene and doctors, it's a no-go. You don't do this, right? So they slid in some sealants because it was break, was spring break, of course. And doctor was like, I'm not really sure how you expect me to get this done. And in my brain, I was like, wow, that's wild to me that she's responsible for the sealants and that I didn't, in that moment I was like, my gosh, she doesn't have someone here to do the sealants for her. That blows my mind, right? So was like, we gotta get this fixed because if a kiddo is here, a kiddo is ready, a kiddo needs sealants, bust it out. 15 extra minutes to get those sealants done is way better than reappointing, bringing them back, getting them settled in again, getting them prepped, like. All the children love going to this specific practice. I'm not gonna lie, they love coming back. She's fantastic. But that's not always the case. So if you are a pedo practice or just even a pedo practice that schedules out really far and this patient needs sealants, it's really fantastic to, like you said, be able to just be like, yeah, let's just pop over here. This, know, EFDA over here or this high jumps over here is gonna get these sealants done for you while this person moves on to their next patient or that patient, that person can stay with that kiddo. give that expanded service while someone else takes the next patient because you're all kind of doing the same things. And I know in pedo model, there's more dental assistants typically than there are hygiene. It's very rare that we see hygienists working in a pedo practice. So having those FDAS on hand is gonna be super beneficial. Maybe one, maybe two, depending on how busy you are, to really bust some of that stuff out. I think that is brilliant. Dana (16:58.23) Yeah, and I've had a lot of general practices switching right, like we talk about sealants all the time, especially to hygiene. Like that's just a great add on for hygienists, even in adults. But I've got a lot of offices where they're switching adult sealants to flowable. Well, the hygienist can't really do that, but guess who can? And then it makes that transition super easy. We can find it in hygiene, we can do it while they're there for their hygiene appointment, but we're able to do a flowable or something that maybe the doctor prefers. So I just think, think about The Dental A Team (17:03.319) Yeah. Yeah. The Dental A Team (17:11.225) Bye. Yeah. Dana (17:26.804) the things that you would love to incorporate or where you might have just a gap as far as a need for it. And if you're a practice that does that, if you're a practice that's like, I just need somebody to kind of fill in those gaps here and there and FDOT is a great solution oftentimes to the obstacles that we're running into. The Dental A Team (17:46.251) I totally agree. My doctor for years was like, this is so frustrating because I would prefer flowable over the sealant material because it doesn't chip as easily, but he was the only one that could place it. So I agree that is brilliant. And I think whether, whether your state allows the APTA space to really be driven like that, to really be utilized, effectively, start thinking about those things that maybe even a regular dental assistant could take from your plate. that you're holding onto that doesn't require that extra schooling or education or letters on their name. Start looking for those spaces. Pedal, general practice, oral surgery, like surgical assistance. There's a lot of stuff they can do too. And a lot of things that assistants can do that we forget to utilize them for and then we get behind or we get stuck. you know, stuck on something. know a lot of my associate dentists, our sticklers, still about their temps. I walk into practices and I'm like, why are you making a temp right now? Like, this is insane. This is why you have dental assistants. And the dental assistants over there twiddling their thumbs like, have nothing to do all day and I don't feel important. And you know, I'm not valued. And it's like, get your butt out of that chair, doc. What can she do to help support you? Or what can he do to help support you to give that patient an even better experience and to get you moving so that that next patient's experience Dana (18:42.038) Yeah. The Dental A Team (19:05.716) isn't negatively impacted just because you're spending time doing things that you don't have to. So, EFDA or not, I think it's really important to look for those areas where a dental assistant can be super supportive. Dana, have you had a lot of practices that have been in search of EFTAs and struggled to find them? Or I feel like my practices that can utilize EFTAs, like they're out there. They're finding them fairly easily and able to get them. into the practice right away, but what have you experienced with that with the hiring search for Aftis? Dana (19:38.646) Yeah. I mean, I definitely think that they're out there. think practices can find them. And then I think if you can't get set, like if there is an assistant that you absolutely love in your practice, who you're like, she's just as a chair side master, or he just is so fantastic. Consider reaching the topic of looking for growth, right? Are you looking for growth in your position? Is this something that you would consider? I think we could implement it really well in the practice. And it's something that I think you would be great at. I think that that's an easy space to look within your practice if you can't find someone out there because oftentimes, we've got that fantastic personality, that amazing chair-side go-getter, that if we had the conversation with them, it's something that they'd consider. The Dental A Team (20:16.892) I totally agree, I think that's brilliant. I actually have a doctor here in the valley that did that and I was like dang, this gonna be everybody. He had like three assistants go and he's like my life's about to be so easy. I was like sure, we're okay. Yeah, so I do agree, I do agree. All right guys, hope, dentist, I hope you found this super valuable and I hope it gave you at least some ideas or sometimes we kinda just feel stuck or lost or like I just need like. Dana (20:26.633) I love it. The Dental A Team (20:39.682) something lost in the hygiene world, like whatever it might be. I hope there was a tip or a trick in here that helped you. For my FDAS out there, you guys are fantastic. For my dental assistants out there, you guys are fantastic. My heart is with all of you guys, my hygienist, front office representatives, like I hope everyone found something super helpful and valuable within this podcast and I want you to share it with each other. especially when it comes to the scheduling. It does get little wild. It's just a little hard sometimes to bend our minds to understand what it is we're looking for. So Dana, I think action items, number one, check your state requirements and your state laws. Like what are you allowed to do with an EFDA? And number two slash three is really explore the idea and figure out where could you add more value to your patient's appointment. reduce your time or not, at least not increase it utilizing an APTA or a dental assistant for more than what you might be right now. Dana, is there anything else you can think of? feel like those are like the two main shebangs right now. Like think about it, figure out what you can do, think about what you'd want to do, and then implement, figure out how to implement within your practice. Yeah, awesome. Dana, thank you so much for being here today. Your ideas were fantastic. I know you've seen so many different things in all the practices you work with. And I know that with your virtual clients, you worked a lot on the scheduling model. So thank you so much for having that knowledge and for being here with me today and letting me pick your brain. I adore you and I appreciate and value your time today. Awesome, everyone. Thank you. Dana (22:12.768) Thanks so much. The Dental A Team (22:16.539) Go leave us a five star review. I wanna know if you enjoyed this. Doctors, I really wanna make sure that this stuff is really hitting home for you, that it's something that's super valuable for you. So reach out to us, Hello@TheDentalATeam.com Let us know if you loved it. Let us know if there's more information that you'd like or if you're trying this model already and you've got some, you know, some stop holds, some holdups, some walls you're hitting, whatever that might look like, reach out to us. We're always here to help. Hello@TheDentalATeam.com and we will catch you next time.
Is there a service in the dentistry field you're interested in learning more about — perhaps enough to add it to your practice? Tiff and Britt dive deep into how to go about expanding services. They give examples, how to tap into your creative side, hurdles that might come up and how to pivot, and more. Episode resources: Reach out to Tiff and Dana Tune Into DAT's Monthly Webinar Practice Momentum Group Consulting Subscribe to The Dental A-Team podcast Become Dental A-Team Platinum! Review the podcast Transcript: The Dental A Team (00:01.134) Hello Dental A Team listeners, we're back today. You've got Tiff and Britt and I'm using your Britt nickname today. Always, I said Brittany Stone last time and like you mentioned, like it's always a little weird. It's so weird to me when people say, this is Tiffanie. And I'm like, it's Tiff. Tiffanie is like so formal. It makes me sound, it either makes me feel like a child or old. Like there's no in -between. It's not my age right now. Whatever, whatever this in -between stages is Tiff. So Britt. Welcome back. I'm excited to be here with you today. I think we have a fun topic that is right up your alley. You love the clinical stuff and this one's diving into clinical. How are you this beautiful afternoon? Yeah. Britt (00:44.197) different crowds. don't know about you, Brittany or like Brett or if you're Tiffanie or Tiff for me, like it just it depends on what crowds and like kind of like what phase of life did I go by my full name or my short name. So but I'm doing great today. I'm excited to be here. Agreed. I love chatting a variety of things, right? So it's always fun. We love it with clients because you never know what they're gonna throw at us, which just makes our life super fun, which I think we love about it. And I think we've got a fun one for everybody today. The Dental A Team (00:54.293) Yes! I agree! The Dental A Team (01:07.628) So true. The Dental A Team (01:13.036) I agree. I agree. I do love I like have a love hate for it. I should say, right? Like I love being thrown curveballs. But then sometimes I'm like, Whoa, my brain. Like this is a big one or dang, I had 15 curveballs but five with five clients this just today like and sometimes it's exhausting but I do love it. I had a client yesterday. We were talking about Britt (01:22.03) That's nice. The Dental A Team (01:38.528) something I can't even I told the last podcast I told you I can't remember all that far. But we're talking about something and I was like, gosh, this is actually it was it's a different type of marketing. And it was two days ago. That's why I can't remember. But they're in a space they're in a they're in Texas. And they're in a community in Texas that is it's just oil fields like they're just it's the oil field industry. And Initially, they're like, how do we stop cancellations? I'm like, fantastic. Like, here's some pieces, here's some things. And then we're like digging through and we're realizing, I'm like, listen, guys, like, let's put these pieces into play for sure. But sometimes you're just in a place that's like, you're going to experience cancellations. These people are getting sent out at midnight for three months to go work in a different oil field. Like they don't have the flexibility. And so it was really cool. And the conversation, the point I say this is like, I had to really think outside the box and I said, you guys, your marketing, your systems, while I have systems that are tied and true and I know that they work, this is why doing it here is different. I may say this is why Dental A Team is different, because calling further in advance on your confirmations or telling them you're going to charge them or coming up with all of these solutions that work for many practices, let's implement those for sure, but you've got a different type of community. I think changing your marketing to we're here when you need us, because that's what you're hearing. And more of that like same day, let's get patients in, hey, call us, switching the marketing efforts is going to work in your area. And the reason that was so cool was because it was so drastically different than majority of other clients. And it was really fun to get that outside the box thinking and like, gosh, okay, let's put our hats on and we brainstorm together and the hygienist in that call was just like, she stood up at the end and she was like, I am so excited for this because at the end of every visit, when I walk them up and I do my NDTR, I tell them, if you need anything else between your appointments, we're here for you, please call. She's like, so this is expanding on that and I was like, you've already been priming your patients for it. The Dental A Team (03:48.199) This is exactly what we need to do. But it was so cool, Britt, because that just highlights like the differences and really getting thrown those curve balls and having fun with it and really diving in and figuring out where are you and how can we expand on that. And that's something I think clinically that we want to talk about today even is really how to expand your range of services. And Britt, I know I didn't prep for this piece and I do this to you guys all the time. I realized that but my brain just is like ping, ping, ping, ping, and I just go for it. So before we even get into like the super doctor clinical stuff, I know that you as a practicing hygienist before you were all into the state you guys, if I need any information on what the dental industry is doing and what's progressing, I know Britt's my girl. So she I know that you have always been so invested in that and I would love to pick your brain right now on. Britt (04:34.747) Thank The Dental A Team (04:44.87) Before we talk about doctor clinical, hygiene clinical, and how did you as a clinician or as being over the clinicians as a manager, how did you help hygiene to expand their services? Britt (04:59.291) Yeah, so I mean, it's always fun. Doctor can do a lot more than the rest of the team, right? So when we get there, there's a lot more options. And for hygienist and even assistants, right? It's gonna be a little bit of like, what can you do within your state, right? That you're under your license, under your scope of practice that you can do. I'd say number one, be aware of that. And even if you want to be able to do more in your state, even I would say encourage you to like. be involved if you want to, you know, you can give anesthesia now and that's something that hygienists want, you want to be able to do one day, be involved with your local associations and things and help move those things forward. Cause it'll help to expand and just make you a, like a more advanced clinician in the end of it. So that's my like one plug is like, cause I know every state's going to be a little bit different and then know what you can or can't do and explore it. And at the end of the day, hygienists and doctors, right? Whatever and assistance, whatever we see that's gonna be a benefit to our patients, kind of like to what you were talking about, custom fit it, but what are the advancements? What are the new things? What can we do that would be beneficial to our patients and in line with our standard of care or something we might wanna evaluate and adding to our standard of care? What is there number one and just get familiar with it. and then see if it's something that you want to be able to add to your practice. know I'm a big laser fan from like back in the beginning when I first got out of school, because it's something we could do in Arizona. I'm a big believer in it for those who can do it. If you're not doing it, it might be something worth considering and starting to look into to see if it'll benefit your patients. I love it. I know these days a lot of hygienists like Airway, Myofunctional are big things that are coming out now that can be super beneficial. And a lot of people are learning that. Even things like for assistance, right? Being able to learn to do things that like maybe your doctor is doing now, but you could do. Those are also things that are expanding. Maybe it's not a new procedure for our practice, but you, it's expanding you and what procedures you can do, which is gonna help the practice overall. So I think just look, be aware of what's out there. Read your articles, be a part of groups, go to your CEs and just be aware of what. Britt (07:14.477) exists so then you can determine what might be good. And I think for doctors, doctors are they've got a lot on their shoulders and they're they learn a lot and they're exposed to a lot. But team members bring stuff up to doctors all the time that they haven't heard about or they didn't know their team would be interested in doing and you can help to kind of have the practice progress and expand things. The Dental A Team (07:36.275) I totally agree. I love all of that. I may you're gonna say laser, I think laser is huge. I think it's a giant benefit. And I think that got really hyped when it you know, first started and then people are like, I don't know. And I think it's something that kind of has fallen off. So I, I surely encourage hygienists to go do that. But something else that you mentioned was the like my functional space, the airway, the sleep apnea, those spaces, and I actually worked with a client over the summer. who had a really fantastic, thriving sleep department. And she did it, it's taken years to get there and she's done it. They've got the systems and processes, everything's written down, write it down. But the interesting piece to me about it was that the doctor barely touched that department. She had a hygienist that loved it, that just saw the need. She, from a personal level, she connected with it. Britt (08:09.317) Thank Britt (08:26.171) Thank you. The Dental A Team (08:34.826) She loved it, she wanted it to do well, and the doctor handed it over to her. So she had a hygienist that went and learned all of this stuff down to the medical billing. Like she's processing the claims for that department. So one of her top hygienists in her practice actually is now running her sleep department. And so expanding her range of services, and I'm not saying go pull a hygienist to start a sleep department. I'm saying look for the things that interest you guys and see how can you expand on that, even if it's something you're already doing, how can you do more of that? I think is what Britt's saying, but watching them thrive in that personally, like she was so happy and she loves hygiene. She still does like a day or two of hygiene a month because she loves hygiene, but she was genuinely lit up talking to me about the sleep department. And so it expanded the services of the practice, but it expanded the services for her and the impact she can potentially make. personally on on the community. So I love that you said that. That highlights a piece that I want to make sure we talked about was what interests you. So hygienists, RDAs, FDs, dental assistants, doctors, associates, all of you guys. What interests you? Like what do you look at and you're like, gosh, that would be cool. But maybe you're afraid to step your foot into and dip that toe in and kind of test the waters or you're like, gosh, it just seems so hard or whatever. reason why aren't you doing it? What interests you? I've had a lot of practices this year that I that were like, gosh, I need to expand services. One PPL reimbursements suck you guys we know that and when you can expand services, you can do higher value things like obviously it makes the production the collections easier. So I had a lot of practices this year that were like, I can't and don't want to drop insurances, but how do I make more? So one space I had them evaluate was to because most people don't put it in their system. I hope you are track, truly track what you're referring out and how many of those things you're referring out. So root canals, perio procedures, implants, oral surgery procedures. I love all of my specialists. I love you. But really if there's something in there for my dentists and FDs and RDAs and all of you guys, like, is there something The Dental A Team (11:00.851) that you enjoy and you want to learn more about, look at what you're referring out. Kavya, I had an office Brit, she was like, I refer out a ton of root canals. I wanna do root canals in office. And I said, okay, we can do that. We can pull root canals back in office. There's courses all over the place that you can go get refreshers on. There's an hour -end course I know of that's fantastic. You can do this. She's like, okay. I said, let's sit on this. Like, let's think about the work it's going to take and let's evaluate how many root canals you're going to do. I talked to her on our next two week call two weeks later. She was like, Tiff, I hate root canals. I was like, yeah, I didn't think you liked them, but I needed to go. We needed to go with it for a second. She's like, I don't want to do root canals. I send them out because I hate them. Cool. Then let's not do root canals. Let's look at the other pieces. So caveat is don't pull things in just to expand services, just to offer more, just to make more money. If you hate doing something, don't do it. Do more of what you love. So we're evaluating here to look at what interests you and how can we do more of it? Are there things, Britt, you mentioned, you mentioned, right, you talked about, right, getting the things that the hygienist can do and within your state it's different, especially when it comes to FDAS, RDAs, dental assistants. It's all over the place, you guys. In Arizona, like, we don't get any special acknowledgement, we just. do everything and you either know or you don't know and you learn it. So, Wild Wild West out here, California, Colorado, like they're Colorado's placing fillings, right? Like that's cool, Tennessee, they're placing fillings, they're like a provider. Here, I actually don't know anymore what that is. I mean, I know what is fine. Britt (12:44.057) It depends. There's some places where it's rural and even hygienists can place fillings if they get certification for it. So sometimes there's some if it's an area in need. that's where it's like, know what's going on in your state. The Dental A Team (12:50.182) Yeah. The Dental A Team (13:00.246) Exactly, exactly. And to speak to that point, like once you do know, Britt, like you said, for those spaces, hygienists, for sure. But then you guys, my RDAs, my FDs, my dental assistants that are listening, I know what it's like to feel like such a big important piece of that appointment and feel like, gosh, I really helped this patient or I really helped my doctor. Go figure out what you can do. And where can you expand so that your expanding your range of services because that adds value in. Britt, I'm sure you've seen it too. You've got practices too, or have worked with practices too, who have these expanded functions that they're able to do in hygiene and or assisting side. And what has that done when they take on those pieces and the support team will call them, right? The support team is like, no, like I can do this. Let me do it. What does that do for the doctors? What have you seen for the doctors? Like what are they available to do them? Britt (13:57.371) Yeah, I want to say first, even for my assistant, I'm a big believer in anyone within a dental office. This is your profession. Like you are a professional. So by expanding your skills, you are just expanding yourself as a professional and what you can do. like, I want to throw that in. Number one is like, I hope you all view yourselves that way. That's how I view all of you because it's true. You have amazing skills. You do amazing things every day. And by working to like the highest level of your ability, taking on those things, learning them from your doctor, getting the trust from your doctor where you're able to go and do it on your own, frees the doctor up to be able to do more of the things that only they can do. I always say doctors are our ultimate limiting factor, right? How many doctors do we have in the practice? How many of the rest of the team do we have? It's usually at least two to one, if not three to one when it comes to doctrine, we're pulling them in a million different directions. So the more we can do, I'll tell you for hygiene, I'm like great when my assistants can do a lot, that means my exams are going to be more on time. So it helps a lot. We can fit in more patients for treatment because we can utilize our assistants and be able to take care of more patients throughout the day. And you guys know, like doctors do a great job of knowing our patients and building that relationship. The Dental A Team (14:59.439) Yes. Britt (15:13.603) hygiene assistant front desk, like you guys know those patients. So you also help to give them a great experience that you're there with them through most of that appointment. You're taking care of a good part of that appointment. Doctor gets to come in and do the part that they need to do. And then you take care of the rest of it. And I have seen for assistance, right? It's performing to the extent that you can on a lot of those things I talked about. But I also have assistants who are helping to like manage team, manage supplies, find, you know, better prices for things. They're learning to design crowns or learning to mill crowns. is so much that you can learn to do. But like I said, just builds you up as a professional and makes it so we can take care of more patients within our office. The Dental A Team (15:59.5) I love that. I love all of that. think one thing I didn't even think about that you mentioned was like learning how to do the crowns or learning how to do the 3D machines or the impressions or the scans that you need to send things out. Like that's, that's a space I didn't even think of. And I love that you said that. Britt (16:10.055) Thank Britt (16:17.5) 3D printers, right? Some of them, like, they're printing out, you know? The Dental A Team (16:18.982) Yes. Britt (16:22.511) retainers, or they're printing out dentures and all that stuff. And there's some cool, there's a lot of cool stuff that are advances if your office has it that like, if they do, or if you're looking into it, those are the things that the team helps drive the doctor so much because the doctor can't do everything right again, they're one person, even if we've got multiple doctors compared to how many team members we have. But if a doctor has a team member that's like, I'm here with you, I'm here to learn it with you, let's do it. doctor is going to be a lot more confident to say all right let's do it and it helps everybody. The Dental A Team (16:58.052) I totally agree. I did a podcast not long ago with the dentist on here. Dave Mogadam you guys can search for it somewhere and they might put them in notes, whatever. But he spoke on that about some advanced courses that he's taken this year, that he actually took some of his dental assisting team with him so that they could learn that stuff because he doesn't. He loves it. He gosh, this man is creative. Like he would sit all day. he has a 3d printer at home. that he plays with that he makes toys with. He brought me a toy like the next day at the office, he brought me a little toy and made me this little octopus thing. But I was like, my gosh, he loves the creative side. But he sees the value in allowing his team to have a part to play in that and allowing his team to learn it. And I don't think you always have to go to the courses. A lot of those places will send somebody out to your practice too. But the value in that is huge. And now he's been able actually, I just talked to him today and he Britt (17:25.435) Yeah. The Dental A Team (17:53.894) had his first sedation day. And so he's been able to like implement other bigger, broader things into his practice to add value to expanding his range of services because his dental assisting team has been able to take things on like that. So I love that you said that. Now within the doctor space, I think it's super important, you guys, I'm gonna go back to the beginning on what interests you. What are you sending out that maybe you could keep in house if it interests you? And why aren't you doing it? That's my biggest question. If it interests you, why aren't you doing it? Overcome that fear, overcome that hurdle, and go for it. I think right now is the perfect time, maybe even a little bit late, to choose your CE for 2025. Like, choose your CE whatever year you're listening to this in. Make sure next year your CE is already chosen by... October. Know what you want next year to look like. And if you don't know, that's okay, like it'll it'll come. That's fine. But plan that out. Because one of the biggest hurdles that I hear from doctors, and the reason they're not expanding services, or they're not doing the thing they truly want to do is time, time, and money. And I have a doctor, we're working on next for next year, reducing the number of days it should take to hit his minimum goal, because he wants to do so much CE and his issue is time. and being able to provide financially for his team. So taking off time at the office and seeing the impact that that has on his team, we've got to like, finagle some workarounds and some goals so that we can still pay the team, whatever, right? But that hurdle, we're working through it. So if you know what your hurdles are, what's holding you back from doing the thing that you truly want to do, now you can plan a workaround. Okay, great. If that's the hurdle, How do we get you more time? And you get into this space, think, Britt, I know I get in this space and you help pull me out where it's just like, I can't see outside of the problem because I'm so in the problem. it is just like, sometimes I'm just like, no, it just sucks. And you're like, okay, it sucks today. We'll come back tomorrow. It's fine. And you navigate that really well with me. So kudos and thank you. The Dental A Team (20:08.871) But sometimes that's the space I think that we get into with expanding services too. Like, gosh, yeah, that would be cool Tiff, but like, how am I supposed to do that? Brett, I have no time. And so, Brett, think something that we do really well is taking our doctors from that space. Like, where is it that you want to go? And this is, want to go, I want to do the service. And then we work backwards and say, cool, this is the path that's going to get you there. What are the hurdles that are going to come up that we can anticipate? not all of them are anticipated, right? But what can we anticipate within this path? What hurdles may come that we can have a pivot ready for so we can work around it. And if it's the time or the money, fan -freaking -tastic, it's October and we're planning for next year. Guess what, guys? We can do anything with your goals. We just add it into your goals and we make the magic happen. that's the easy space of it. But what interests you? Why aren't you doing it? What are you sending out? What are things that your support team can help with and do they want to? And then choose your CE for next year. Those are my biggest points. And Brit, for someone that's just like on the edge of their seat, gosh, this Brit and Tiff, are freaking amazing. And you've got me pumped up and ready to go. But they're like, ha. And then two weeks later, they forgot about this. What do you suggest for them? Like, how do they stay motivated in this space of potential busy and chaos? And I'm not ready to look at that. What would you say to your client? today to keep that motivation. Britt (21:39.163) Yeah, I think that right thoughts not written down or put into motion get lost, right? And so we've got to do something to where either It's maybe going on a whiteboard in your office. So you see it there regularly and you know that that's something you want to work towards. Maybe it's like looking up the course and when's the next date and putting that up somewhere so that you know that that's what you're working towards or having some sort of accountability buddy. I think if you're normal, we all get to those spots where it's like, I can't see past my nose right now and I need someone to help me see past my nose and we've got to step away or get someone from an outside perspective to pull us out of it. thing with treatment and so it's like make it something that's gonna put into motion. Don't make it just a thought, write it down somewhere, schedule the event, pick what you want to go to, something to move forward and you know what doctors? Go into a course about it. It still doesn't tie you to anything right now. Like, so if you're like, hey, I'm interested in it, but like, my gosh, it seems like such a big thing to tackle. Start with one thing. Start with one thing and see if you're as interested as you are. And I say the same thing to... I'll just add one last thing to sometimes it's the market we're in that's also going to drive you right. I've got some docs who are in areas where we may not have a lot of specialty around. And so they're like, my gosh, I feel for my patients. I want to be able to do more for them, but I don't know. Britt (23:09.231) This is where Tiff and I are coaching you. Take the push, go take a course on it and just start to explore it and you get exposed to people who have done it. You can do whatever you want. Like at the end of the day, if you really want to do it, you can. And sometimes it's just explore it first, take the first step and that's all you need to do right now. And then take the next step. The Dental A Team (23:28.787) Yeah, one step at a time. I love that. I love the whiteboard idea. Alright guys, I hope you feel motivated. I hope you feel powerful. I hope you feel excited to go find something. It doesn't have to be grandiose. It doesn't have to be something big. But go find something that excites you that you can learn or you can add and you can expand what you're offering in the next year. Go do it. Drop us a review below five stars are always appreciated. Let us know what you decide I want to know what you guys are doing too because Britt I don't know about you but that's where a lot of our Knowledge base comes from is picking the brains of the people we work with so share that breadth of knowledge Leave us a review Reach out. Hello@TheDentalATeam.com we want to hear from you guys And if you need help working that backwards like if you're like gosh, I just can't see through it you guys We have coaches too. I have a coach that helps me work through things in my life that helps me work through my health and fitness and mindful journey like all of those pieces. We all have coaches and we are here for you for those types of things. That's what we love. That's where our passion lies. And I want you guys to understand if you need it or if you just need a little smidgen of direction, reach out. Hello@TheDentalATeam.com. are here to help you guys. And I hope you have a fantastic rest of your day.
Millions of prescriptions of thyroid medication will be filled this year and the vast majority of them will be for levothyroxine. Of those millions, only about 10% or so will go to a class of thyroid medication called natural desiccated thyroid. Despite being only 10% of all prescriptions, thyroid patients have a clear preference for it. Not only does it help with weight loss, but it also can help better control thyroid symptoms based on surveys of thyroid patients. There's only one problem: Doctors don't like to prescribe it. Unfortunately, they are under the impression that NDT is an inferior medication to levothyroxine which is why today, I'm busting these NDT myths. Here they are, in no particular order: 1. Claim #1: Taking NDT Will Cause Bone Loss & Heart Problems Long-term studies show this isn't true PROVIDED you are not taking more than you need. 2. Claim #2: Newer Synthetic Medications Are More Effective The idea here is that NDT may cause side effects because of its T3 content. This may happen, but it's also the reason that people prefer NDT... because it works. 3. Claim #3: NDT is Not FDA-Approved This is true but irrelevant. NDT has been use since 1890 so it was grandfathered into the FDAs newer requirements. 4. Claim #4: NDT is Old-Fashioned This isn't true either as all thyroid medications contain the same bio-identical thyroid hormones. The same T4 that is found in levothyroxine is also found in NDT. 5. Claim #5: Taking NDT Will Cause Mad Cow Disease NDT comes from pigs (not cows), and there's never been a reported case of Mad Cow disease in the US. 6. Claim #6: Taking NDT Will Increase Thyroid Antibodies This is theoretical and may be a problem for a rare subset of people, but not enough to warrant that everyone avoids it. Claim #7: NDT Isn't A Real Medication Because it Can Be Purchased Over The Counter NDT is not the same thing as over-the-counter thyroid glandulars which is what this claim confuses. Need help optimizing your thyroid medication? Check out this video next: https://youtu.be/Yyf3XgB97l0?si=yBjZ094s6CIylfl9 Download my free thyroid resources here (including hypothyroid symptoms checklist, the complete list of thyroid lab tests + optimal ranges, foods you should avoid if you have thyroid disease, and more): https://www.restartmed.com/start-here/ Recommended thyroid supplements to enhance thyroid function: - Supplements that everyone with hypothyroidism needs: https://bit.ly/3tekPej - Supplement bundle to help reverse Hashimoto's: https://bit.ly/3gSY9eJ - Supplements for those without a thyroid and for those after RAI: https://bit.ly/3tb36nZ - Supplements for active hyperthyroidism: https://bit.ly/3t70yHo See ALL of my specialized supplements including protein powders, thyroid supplements, and weight loss products here: https://www.restartmed.com/shop/ Want more from my blog? I have more than 400+ well-researched blog posts on thyroid management, hormone balancing, weight loss, and more. See all blog posts here: https://www.restartmed.com/blog/ Prefer to listen via podcast? Download all of my podcast episodes here: https://apple.co/3kNYTCS Disclaimer: Dr. Westin Childs received his Doctor of Osteopathic Medicine from Rocky Vista University College of Osteopathic medicine in 2013. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Childs is no longer practicing medicine and does not hold an active medical license so he can focus on helping people through videos, blog posts, research, and supplement formulation. To read more about why he is no longer licensed please see this page: https://www.restartmed.com/what-happened-to-my-medical-license/ This video is for general informational, educational, and entertainment purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between D
Cynthia Lo Bessette and Matt Horne of Fidelity Digital Asset Management join the show. In this episode we discuss: The history of digital asset innovation at Fidelity. The decision to operationalize a digital asset-management capability under Fidelity's Asset Management business unit. The launch of the Fidelity Bitcoin ETF and the path to getting this product to market. How Bitcoin ETFs are currently being consumed and the distribution of these products to various investor types and platforms. How Fidelity is approaching the tokenization of real world assets. Broader views on the future of public blockchain assets and the types of opportunities for asset managers. Learn more at Fidelity Digital Assets
In this episode of the Global Medical Device Podcast, host Etienne Nichols sits down with Kim Kaplan from ISACA at the MD&M West trade show in Anaheim, California, to discuss the pivotal Voluntary Improvement Program (VIP). This conversation sheds light on how the program, stemming from FDA's Case for Quality initiative, utilizes the Capability Maturity Model Integration (CMMI) to push medical device companies beyond compliance, towards excellence. Kaplan elucidates the history of VIP, its benefits, and how it aligns with the FDA's vision for a more innovative and quality-focused MedTech industry.Key Timestamps:[00:00:30] Introduction of Kim Kaplan and the Voluntary Improvement Program[00:05:00] Explanation of CMMI and its adoption in the medical device industry[00:15:45] Distinctions between CMMI and other quality methodologies[00:25:30] In-depth discussion on the specifics and benefits of the Voluntary Improvement Program[00:40:00] How companies can implement change based on VIP insights[00:50:00] FDA's perspective and regulatory opportunities tied to VIP participationNotable Quotes:“Organizations that are compliant aren't necessarily avoiding the types and numbers of issues faced by non-compliant ones.” - Kim Kaplan“CMMI focuses on the 'what' to do rather than the 'how,' allowing for a framework that compliments existing processes.” - Kim Kaplan“The Voluntary Improvement Program isn't just about compliance; it's about embracing continuous improvement as a culture.” - Kim KaplanKey Takeaways:Understanding VIP: The program aims to elevate quality and operational efficiency through a collaboration involving FDA, MDIC, industry stakeholders, and ISACA.CMMI's Role: CMMI's flexible, globally adopted framework helps MedTech companies identify and implement best practices in product development and project management.Benefits of Participation: Beyond improving quality, VIP participation can streamline regulatory processes, fostering quicker innovation and market access.Practical Tips for Listeners:Engage with CMMI: Consider how CMMI's framework could complement your company's existing quality and project management processes.Explore VIP: Assess your organization's readiness and potential benefits from enrolling in the Voluntary Improvement Program.Continuous Improvement: Embrace continuous improvement, not just for compliance, but as a cornerstone of your company culture.Future Questions:How will the integration of AI and digital health technologies impact the criteria for CMMI and VIP?In what ways might the Voluntary Improvement Program evolve to further incentivize innovation in MedTech?How will FDA's regulatory framework adapt to the rapid advancements in medical device technologies?References and Resources:Etienne Nichols on LinkedInKim Kaplan on LinkedInFDA's Final Guidance on the Voluntary Improvement ProgramISACA's overview of FDAs Voluntary Improvement Program (VIP)Regulatory opportunities of the...
Dr. Galati gets going tonight talking about the breaking news on the FDA approval of resmetirom, brand name (rezdiffra) and the impact it has. He continues the fatty liver conversation on the fibrosis and scaring of the liver. Dr. Galati also replays last weeks interview with Dr. Dang Nguyen on Colon Cancer and the awareness surrounding it.
This episode of the Global Medical Device Podcast delves into the world of FDA submissions, specifically focusing on the eSTAR program. Host Etienne Nichols leads an insightful discussion exploring the intricacies, benefits, and strategies for using eSTAR effectively in medical device regulatory submissions.To discuss this topic, we brought in the following experts:Patrick Axtell, Ph.D., the Senior Tools & Templates Engineer for the Office of Regulatory Products at CDRHLisa Pritchard, Vice President of Regulatory, Quality, Clinical and Engineering at DuVal & AssociatesKathy Herzog, Senior Regulatory, Quality & Compliance Consultant at DuVal & AssociatesAs of now, all 510K submissions must use the eSTAR program. eSTAR is designed to streamline the FDA submission process, making it more efficient and standardized. This episode is a must-listen for anyone in the medical device industry looking to navigate the complexities of FDA submissions with a focus on the evolving eSTAR program.Expert Insights:Patrick Axtell: Discusses the development of the eSTAR program, its purpose, and benefits, including standardization and automation in the submission process.Lisa Pritchard: Shares her 30-year experience in regulatory space and her initial skepticism about eSTAR, which later transformed into advocacy for the program.Kathy Herzog: Provides practical advice on using eSTAR, emphasizing the importance of understanding and navigating the program effectively.Key Strategies:Use the help features within eSTAR as a quality control check.Start at the beginning of the template to avoid missing critical sections.Prepare your submission content outside eSTAR before populating the template.Consider the executive summary as a mandatory, not optional, part of your submission for effective advocacy.Future of eSTAR: eSTAR is evolving to include more types of submissions (e.g., PMAs, presubs) and may soon incorporate AI and other technological advances for enhanced efficiency.Quotes:"Standardized submission means that the reviewer can quickly find information...a huge benefit for both applicants and reviewers." - Patrick Axtell"Even after 30 years, I always open those help boxes in eSTAR...each submission is unique." - Lisa Pritchard"The key with eSTAR is eSTAR(t). You just have to get started...no substitute for just getting familiar with the template." - Kathy HerzogReference Links:Lisa PritchardKathy HerzogEtienne NicholsGreenlight GuruDuVal & AssociatesClient Alert: "eSTAR & I"FDA eSTAR Program webpageFDA electronic Submission Template guidance for 510(k) Submissions
Newsmax Jerusalem Bureau Chief Daniel Cohen joins us with the chilling story of watching the UNEDITED Hamas video of terrorists murdering families. How Israel views the Biden Administration and why Daniel and his family decided to stay in the war torn country. Plus, we dig into the FDAs cozy relationship with the Gates Foundation. Money talks, even if it makes you sick. Podcast Production: Bob Slone Audio Productions
Earl starts the show discussing the efficacy of over the counter medications and the FDAs hesitancy to remove products from the shelves. Then, he discusses tax breaks for the wealthy and the impact they have on the federal deficit.
Description:In this episode, host Etienne Nichols and Shannon Bennett, a regulatory affairs expert in the diagnostic testing space dive into the FDA's proposed rules for Laboratory Developed Tests (LDTs) and In Vitro Diagnostic products (IVDs). Shannon breaks down the past and present regulatory landscapes of LDTs, the differences between IVDs and LDTs, and what the FDA's changes could mean. They discuss the cost implications and the learning curve for labs new to FDA's processes. Shannon explains the FDA's four-year phased plan for labs to comply with the new rules, touching on the challenges at each phase, like the administrative burden and the influx of submissions the FDA might have to review. Focusing on the transition for new or modified tests, Shannon emphasizes the need for more guidance from the FDA and educational efforts to help labs understand the new terms and requirements. We also discuss the potential disruption to healthcare and urge labs to actively comment on the draft regulations to the FDA. Through engaging dialogue, this episode is a deep dive into the regulatory shifts in the lab industry, making it a great listen for those in the regulatory and healthcare fields.Some of the highlights of this episode include:Concerns regarding the handling of new or modified tests during the four-year phase-in period, emphasizing the need for clear guidance alongside historical tests.Discussion on a unique approach from the Valid Act called technology certification, aimed at easing submission and review burdens on both labs and the FDA.The significant educational effort required from the FDA to help labs navigate new terminologies and requirements.The potentially disruptive impact on healthcare, given the critical role laboratory testing plays.Encouragement for labs to actively provide comments on draft regulations to the FDA, advocating for a balanced approach to regulatory developments.Year One: The focus is on adverse event reporting, with Shannon suggesting additional FDA guidance to manage irrelevant adverse event reports.Year Two: registration and listing phase is discussed, pointing out the clerical burden on labs despite having most required information.Year Three: The introduction of Quality System Regulation (QSR) or Good Manufacturing Practice (GMP) requirements in year three is explored, with Shannon mentioning some overlap with existing CLIA compliant quality systems but highlighting FDA's additional documentation expectations.Year 3.5 & 4: Shannon delves into the submission of Premarket Approval Applications (PMAs) for high risk, low, and moderate risk tests in year three and a half and year four, underlining the challenge for labs in categorizing their tests and for the FDA in handling a potential influx of 80,000 to 100,000 new submissions.Quote:"I think the bottom line is this will be potentially very disruptive to the healthcare environment. Lab developed tests. There are studies that have shown that 70% of the information in the medical record is due to laboratory testing. So obviously, they play a really important role in the healthcare environment." - Shannon BennettReference Links:Shannon Bennett on LinkedInIVDs and LDTs: What's the Difference?FDA Proposes New Rule to Regulate LDTs...
In this episode I am explaining things like why nutrition labels are allowed to report the calories from net carbs rather than the total calories, how they get away with labeling things that contain fats as “fat free,” and discussing tons of other misleading nutrition labels. - For more information about the FDAs regulations on nutrition labels, check out this site
Tales From the Front Desk - Umm.. that wasn't my wife! Welcome to r slash malicious compliance / pro revenge! Where ridiculous people tend to get EXACTLY what they deserve! #maliciouscompliance #unclereddit #funnyredditstories We narrate Funny (or at least ironic) Reddit Stories about Tales From Tech Support as well as other funny Reddit topics! Be sure to scroll down to check out some of our other playlists! Today's stories are from the subreddit r/talesfromthefrontdesk #maliciouscompliance #unclereddit #talesfromtechsupport Thanks for watching! Please subscribe and come back for more funny Malicious Compliance Reddit stories. I'll try to post as often as possible while we build the channel.
In this episode Joe and Joey discuss the Aaron Rodgers to the JETS trade rumors, Kevin Durant's injury, and the FDAs rejection of Elon Musk's Neuralink.
This is the Weight and Healthcare newsletter! If you like what you are reading, please consider subscribing and/or sharing!Novo Nordisk (the same company that made a literal fortune by price gouging with insulin,) has taken another step to follow through with their promise to shareholders to generate massive profit from their new weight loss drug Wegovy by getting FDA approval to market the drug to adolescents ages 12 and up.This approval is based on a 68-week trial. They started with 210 participants who were randomized 2 to 1 to get the drug or a placebo, with 180 completing the full 68 weeks.At week 68, a total of 95 of 131 participants (73%) in the semaglutide (Wegovy) group had weight loss of 5% or more. The youth subjects had greater incidences of gallbladder problems including gallstones, low blood pressure, rash, and itching compared to adults treated. The most frequently reported adverse reactions were nausea, vomiting, diarrhea, headache, and abdominal pain.There are some obvious things here.First, according to disclosures, every single researcher on the trial takes money from Novo Nordisk. That's not proof of impropriety, but it's certainly something to know (You can find a quick guide to evaluating weight science research here.)Second, it shouldn't be shocking that a drug that causes nausea, vomiting, diarrhea, and abdominal pain will also lead to, at least short-term, weight loss. In other studies of similar GLP-1 agonists we have seen that higher amounts of weight loss are predicted by longer onset of gastrointestinal symptoms so there is some question as to how much of the weight loss is the action of the drug on hormones and slowed digestive motility, and how much is just about giving people flu-like symptoms.Third, at 68 weeks this is a relatively short-term study. In a follow-up to the 68 week adult study of the same drug (Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension,) one year after they had stopped the drug, participants had regained two‐thirds of the weight loss they lost, and lost about two-thirds of their cardiometabolic improvements. This is in line with the significant data showing that almost every weight loss attempt ends in full weight regain within 2-5 years, and it means that, in addition to the side effects of the drug, it may also be exposing those who use it to the risks of weight cycling.Their follow up from weeks 68 (when the adolescents stopped the medication) until week 75 shows a similar pattern. Novo Nordisk's (incredibly profitable for them) answer to the fact that people regain weight after going off the drug, is that they should just stay on the drug, forever. This is a problematic recommendation at best for adults, especially considering it's only based on a 68-week trial during which participants experienced serious side effects including pancreatitis, gallstones, kidney failure, increased heart rate and depression or thoughts of suicide and a risk of tumors that earned Wegovy a boxed warning – the FDAs strongest warning.When it comes to children, I think it's likely far worse. Remember that this is a drug for Type-2 diabetes that was repurposed by Novo Nordisk when they found that weight loss was a side effect and that the market for weight loss drugs was significant. It also allowed them to capitalize on their long-game efforts of having simply existing in a higher-weight body considered a “chronic lifelong health condition” (regardless of actual metabolic health) for which “lifelong treatment” is, they claim, appropriate.So what happens when you put a 12-year-old (who is far from being done growing) on a large dose of a type 2 diabetes medication with the goal of interfering with their hormones and slowing their digestive system and a risk of serious side effects, and then keep them on it indefinitely?For Novo Nordisk – massive profits. The sticker price for Wegovy for is $1,350 per month and their behavior around insulin has proven that they are very willing to prioritize profit over human life.For the patients? Nobody knows. The kids who are prescribed this medication are going to be the ones to find out – very possibly the hard way.Update: The two-year study of Wegovy gives more insight into the dangers of these drugs. In this study, they break the adverse events into “events per 100 patient years” In terms of total adverse events, the total is 532.3 per 100 patient years. For serious adverse events, it's 6 per 100 patient years. For adverse events that lead to discontinuation it's 4 per 100 patient years.This may not seem like a lot until you think about the fact that when these drugs are prescribed to a 12 year old, even if we assume a life expectancy of just 70 years, someone who starts the drug at 12 could individually have 58 patient-years with an average of 308 total adverse events, 3.48 serious adverse events, and 2.32 events that lead to product discontinuation. (And remember that “produce discontinuation” means, at the very least, weight regain and loss of cardiometabolic benefits based on Novo's own studies. I do a deep dive into the two-year study here. As a reminder, there is an option to support the health of fat kids, rather than risking their lives and quality of life trying to make them thin.Did you find this post helpful? You can subscribe for free to get future posts delivered direct to your inbox, or choose a paid subscription to support the newsletter and get special benefits! Click the Subscribe button below for details:Liked this piece? Share this piece:More research and resources:https://haeshealthsheets.com/resources/*Note on language: I use “fat” as a neutral descriptor as used by the fat activist community, I use “ob*se” and “overw*ight” to acknowledge that these are terms that were created to medicalize and pathologize fat bodies, with roots in racism and specifically anti-Blackness. Please read Sabrina Strings Fearing the Black Body – the Racial Origins of Fat Phobia and Da'Shaun Harrison Belly of the Beast: The Politics of Anti-Fatness as Anti-Blackness for more on this. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe
Several scanners have been cleared by the FDA for clinical pathology work, but what about FDAs stand on all the nonclinical pathology work done in a regulatory environment? Specifically the work done in the Good Laboratory Practice (GLP) compliant environment?Can we use the slides without restrictions in lieu of glass slides?What part of the digital pathology system do we need to validate?How do wemaintain and archive the whole slide images used for the pathology portion of the nonclinical toxicologic studies?Good news!There is an official FDA draft guidance for the industry that asks all those and a few more questions and answers them at the same time.In this episode I will go through the guidance for you, so that you don't have to spend time reading this document. But if you feel like doing it anyway, it's available for you to download below in this episode's resources.And in case you want to skip the whole episode (which I sincerely hope you don't! Believe me, it's pretty fun for and FDA guidance episode:), the answer to most questions is YES.Talk to you inside the episode!This episode's resources:Use of Whole Slide Imaging in nonclinical Toxicology Studies: Questions and Answers. Draft Guidance for the Industry.Dr. Aleks Zuraw on TikTok :)And if we are not connected already, let's connect on LinkedIn!
«Du er ikke en hest. Du er ikke en ku. Seriøst, alle sammen. Slutt med det,» skrev U.S. Food & Drug Administrations (FDA) på Twitter, da de gikk til krig mot Ivermectin. Nå ror de så det spruter, for nylig måtte de svare for seg i en høring i Texas. Nå heter det seg at det bare var en «uformell veiledning.» Men det er mer. Det er store penger i omløp og vi opplevde et mediekorps som marsjerte i takt. Erling Marthinsen gir sin dom over FDAs opptreden, som rakner i sømmene, mens Christian Skaug tar for seg algoritmer og Elisabeth Rooney beærer Rett på sak med sin første opptreden. Velkommen til ukens siste Rett på sak! Hvis du setter pris på sendingene: Vipps oss på 638941. Alle bidrag hjelper. Lag en konto på Odysee her! – Odysee vil da gi oss poeng som hjelper oss å klatre i algoritmene! Følg oss på Rumble. Følg oss også på PodBean, iTunes og alle steder der podcasts finnes. Husk å rate oss med 5 stjerner, så flere likesinnede sannhetssøkere finner oss der! Kjøp julegavene fra Document!
In September of 2022, the White House held the first conference focused on hunger, nutrition, and health, in 50 years. The convening served as the Biden-Harris administration's call-to-action to end hunger, and increase healthy eating, and the physical activity among Americans, by the year 2030. But how successful was this event in actually catalyzing a national strategy? We'll hear perspectives on this from Dr. Susan Mayne, Director of the Center for Food Safety and Applied Nutrition at the Food and Drug Administration. Interview Summary Susan, I've respected your work for so many years. First, as a scientist - we were together on the faculty at Yale for a number of years. And now you work in government too. So it's really nice to hear the word "perspectives." So let me ask this as the first question. What do you think was the best thing that came out of the White House Conference? From my perspective, it really drew a huge focus on the problem that we have been facing for a long time. The epidemic of diet-related chronic diseases, and how having good nutrition really can help reduce those diseases. As you know very well, this is something I've been working on for my entire career. What the White House Conference did is it really put a focus on that, provided inspiration and commitment to action, associated with this White House Conference. There were two very important deliverables that came along with that. The first one is a roadmap of actions that the federal government can take. In the “all of government” approach to end hunger and reduce diet-related diseases, while reducing disparities. The second deliverable is really a number of other commitments that others have made to really tackle this problem. I think we see this as a really great opportunity to accelerate the efforts that we have been trying to do, to get to a healthier food supply, and turn the tide on the epidemic of diet-related chronic disease that we have in this country. Let's talk about what the FDA can do in particular. There aren't many people out there who probably know the full portfolio of FDA activities around food, because there are a number of them. So how do you think FDA can make a difference with this goal to end hunger, and to prevent diet-related diseases? Yes, there are many ways the FDA can make a very big difference, and we have several deliverables in the White House strategy that really take advantage of two things that we do. One is through our labeling authorities, and we can discuss some of the labeling authorities and how those can really help turn the tide on diet-related chronic diseases. But we're also working to have a healthier food supply for all, using tools outside of our labeling authorities. It's really that combination of things that we can do, and how that can be leveraged by other federal agencies, so that we can be part of the solution. Obviously, FDA can't solve this problem alone, this is a multifaceted problem. The problem of diet-related chronic disease, it requires multifaceted solutions. But FDA is proud to be part of the federal workforce that's really trying to impact this problem of diet-related chronic disease. When you mention "a healthy food supply," in the context of FDA, some people would automatically think "That's all about food safety, let's make sure we don't have foodborne illnesses." That's, of course, important, but you're talking about a different thing: the long-term health consequences of food. FDA has a role there too, I'm suspecting? Yes, we do. And our title, the name of the center that I lead, is the Center for Food Safety and Applied Nutrition. So nutrition has always been a foundation of what FDA does, and much of our work actually intersects the two together. And I'll just give you one example is the work we are doing on food safety, for example, to get to better produce safety, so we have fewer outbreaks related to produce. That's also critically important for our work on nutrition, because we want consumers to have confidence in fresh produce, consume more of it, to be more consistent with what the dietary guidelines recommends, and that instead will improve nutrition. So food safety and nutrition are both interrelated in the work that we do at FDA. If the goal is for people to be able to eat healthier foods, part of that is people knowing how healthy foods are. So how do you work on that issue? Well, a couple things to emphasize, one is that education is critically important. And, when it comes to education around health and nutrition, we partner with the US Department of Agriculture, the Centers for Disease Control and Prevention, in a lot of these educational efforts to educate consumers, to make sure that they know what healthy eating should look like. But interestingly, another piece of this is that if you ask consumers where they go to, and who they trust for nutrition information, they will frequently tell you that their most trusted source is their doctors. It's also important, not just that the federal agencies are working on this, but medical professionals also really need to be educated about nutrition, so that they can help their patients. We have produced some continuing education models for physicians on food labeling, and how they can use that to counsel their patients. I would like to see more nutrition incorporated into the medical exams and board certifications. So we incentivize more nutrition training for physicians, and some of these concepts are built into the national strategy on nutrition, released around the White House Conference. You've mentioned food labeling several times, and when people think about food labels, they naturally think of the ingredient label, and they think of the nutrition facts panel that's on the side, or the back of packages. But there's been talk over the years about the possibility of some sort of a labeling system on the front of the package, which would be a quick guide for consumers to understand how healthy a food might be overall. I'm just not aware of where discussions stand in FDA about that now, and I'm hoping you might bring us up to date. Happy to. You know, we look at food labeling holistically. There are different claims that we regulate on food labels, things like a healthy claim that currently exists that we've been working to update. Those are claims that we regulate. You asked specifically about front-of-pack labeling. As part of the national strategy on nutrition, we did make a commitment to work on developing a front-of-pack labeling scheme that could help consumers make those types of decisions quickly, through front-of-pack labeling. So there are many labeling tools that we have, whether it be claims around healthy, dietary guidance statements, front-of-pack labeling. In addition to the nutrition facts labels and ingredient statements. Those are all pieces that can really help inform consumers about the foods that they are purchasing. You have to look around the world at these front-of-pack package labeling systems, there are lots of different types. I mean, some are like a stoplight program, with red, yellow, and green symbols to indicate how much overall nutrition, or unhealthy things that food might have. Others talk about specific ingredients. Is there a consensus around the field now about which of those systems might be most effective and helpful to consumers? So, one of the things we've been doing is really looking at that international landscape. We have learned a lot about what different countries are doing, and what those countries have learned about the various systems. As part of our commitment to develop a front-of-pack label system in the United States, we are learning from the vast international experience that is out there. We are in early phases of this, but I can assure you that FDA's work will be informed by what's happening in the international landscape. At the same time, we are interested in how our own consumers respond to different front-of-pack labeling systems. We have begun, and completed, a first-round of consumer studies. We have a consumer studies branch in my center where we test how consumers interact with various labeling systems. So we've completed some qualitative research, some focus groups, and we're looking forward to additional consumer research that would help guide us being informed by our own work, as well as what's happened in other countries, in terms of a potential path forward for the US. I'm really happy to hear that, because that kind of work in the United States needed to be done in the kind of big way, you're probably able to do it. So I'm really happy to hear that news. So if you come upon a system that you feel might work best in our own country, what's the process for actually having something like that on packages? I mean, does Congress need to approve? Is that something the FDA can do on its own? What sort of route might it take? I can't foreshadow specifically which route we would take, but FDA will issue guidance, or regulations, in terms of where we would be going. Under any scenario, it's important to us that we get public comment on anything that we would be doing. So for example, we could issue a proposed rule on a particular labeling pathway, that would then go through a public comment process before we would make anything final. A key part of all of this work is extensive stakeholder engagement, and that means hearing from a number of different stakeholders; our consumer groups, the academic sector, the industry, to provide information into our process. There would be multiple places where we get input for any system that we would be moving forward. It obviously would involve extensive public comment before we would finalize the next steps. It'll be really interesting to see what happens with that. And ultimately, what we might find on the front of packages in the United States. Let's return to the national strategy. The national strategy discusses all of the government response. You mentioned before connecting, with CDC, USDA, other parts of government. Are there some examples you could give us about how different government agencies can work together to make progress? How that might work, and what kind of issues might be involved? Sure, with regard to some of our own work, for example, we're not only using our labeling authorities, but we've also taken other steps to have a healthier food supply. I'll give you one example, and that's our work to reduce sodium in packaged foods. We have issued targets for industry to level the playing field, and gradually reduce the amount of sodium in the food supply. Our sodium targets hit not only packaged foods, but also restaurant and retail as well. What we've done in the national strategy is we've talked about how other government partners can leverage FDA's sodium work. For example, the VA, the Veteran's Administration, they are planning to increase procurement of lower sodium foods consistent with FDA's targets. We're also partnering with HHS administration for community livings administration on aging, to help older adult nutrition programs. That they would provide lower sodium options consistent with FDA's targets. USDA has been using FDA's targets as they're working to reduce sodium in school meals. This is an example where FDA can take an action, and it can be leveraged and amplified, including through the power of procurement through the federal government, to get to a healthier food supply for all. I'm really happy you mentioned "procurement," because you're right, that can be very powerful, and the government has so much sway in that respect. This is the final question, let me just follow up on this sodium issue, because I think it's really an interesting one. Consumers might hear the term "lower sodium," and think that means lower taste. I think the strategy that some people have discussed is that the diet became high in sodium without people really knowing so much that it was happening. People just got accustomed to a very high level of sodium in their day-to-day foods. But that if it gradually got reduced, it would happen in a way that consumers wouldn't even notice each little decline, because it would be gradual. But they'd become re-calibrated to a new standard that they would find just as pleasant, it would just be lower in sodium. Is that kind of the way the thinking goes? That is a key part of our sodium strategy. What we heard from the food industry is that if they tried to reduce sodium in foods to promote better nutrition that consumers might recognize that those products tasted different from other foods that had not been reduced in sodium. That in order for us to make progress, we needed to level the playing field, so all of the industry was reducing sodium incrementally at the same time. The reason this can work is because sodium is an adaptive taste, and so we can all adapt to these lower sodium foods. Consumers wouldn't even notice these minor adjustments as you begin to ratchet down the amount of sodium in the food supply. These changes can help, gradually, across a population, have really important health benefits. Bio Susan Mayne is the Director of the Center for Food Safety and Applied Nutrition (CFSAN) at the Food and Drug Administration (FDA). In this position, Dr. Mayne leads the Center's development and implementation of programs and policies related to the safety and labeling of foods, food and color additives, and cosmetics. CFSAN's responsibilities also include fostering the development of healthier foods and ensuring that consumers have access to accurate and useful information to make healthy food choices. Mayne received a B.A. in chemistry from the University of Colorado. She earned a Ph.D. in nutritional sciences, with minors in biochemistry and toxicology, from Cornell University. Prior to joining the FDA in January 2015, she spent nearly three decades at Yale University, where she held an endowed chair as the C.-E.A. Winslow Professor of Epidemiology. Her distinguished career there included two leadership positions: Chair of the Department of Chronic Disease Epidemiology and Associate Director of the Yale Cancer Center. She completed two consecutive terms on the Food and Nutrition Board of the National Academy of Sciences, and a five-year term on the Board of Scientific Counselors for the U.S. National Cancer Institute.
Federal Court Holds FDA Regulation of Premium Cigars to be “Arbitrary and Capricious”. YES. Called “not reasoned decisionmaking.” FDA must reset if they want to regulate premium cigars. We relish this ruling with a Cohiba Puro Dominicana and some Hamilton Navy Strength Rum.
Pfizer and Moderna have figured out a way to use regulatory capture to get their reformulated Covid-19 shots approved WITHOUT further clinical trials, allegedly. They call their scheme the “Future Framework” and it was voted on by the FDA's V*ccines and Related Biological Products Advisory Committee (VRBPAC) on June 28th, allegedly. The “Future Framework” is reckless, allegedly. We explore what this means for YOU and how the FDA has abandoned science and its statutory duty to protect the public, allegedly. These are the FACTS about the FDA's new so-called "Future Framework"...allegedly. Thank you for supporting the PODCAST...allegedly! References: https://elink.io/p/future-framework-980623b https://anchor.fm/jsk/episodes/FDAs-new-Future-Framework---29-e1kmm9q --- Send in a voice message: https://anchor.fm/jsk/message Support this podcast: https://anchor.fm/jsk/support ★ Support this podcast on Patreon ★
Pfizer and Moderna have figured out a way to use regulatory capture to get their reformulated Covid-19 shots approved WITHOUT further clinical trials, allegedly. They call their scheme the “Future Framework” and it was voted on by the FDA's V*ccines and Related Biological Products Advisory Committee (VRBPAC) on June 28th, allegedly. The “Future Framework” is reckless, allegedly. We explore what this means for YOU and how the FDA has abandoned science and its statutory duty to protect the public, allegedly. These are the FACTS about the FDA's new so-called "Future Framework"...allegedly. Thank you for supporting the PODCAST...allegedly! References: https://elink.io/p/future-framework-980623b https://anchor.fm/jsk/episodes/FDAs-new-Future-Framework---29-e1kmm9q --- Send in a voice message: https://anchor.fm/jsk/message Support this podcast: https://anchor.fm/jsk/support ★ Support this podcast on Patreon ★
In this episode, I highlight why it's bitcoin and not crypto that you want to focus on. The recent price action and news have made it top of mind to highlight some important items and lessons to learn from others. At the time of recording Bitcoin's price was $29,990. Links Mentioned https://www.veterinariansuccesspodcast.com/episode/84-radio-show-bitcoin-why-it-matters-for-everyone-in-veterinary-medicine- (Episode #84 - Bitcoin for ALL) https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/bitcoin-first.pdf (Bitcoin First ) https://twitter.com/PrestonPysh/status/1526259839407726592 (LUNA Tweet Thread) https://www.uncerto.com/only-the-strong-survive (Only the Strong Survive) https://www.suresats.com/post/ethereum-s-centralization-dilemma-through-lido-staking (Ethereum's Centralization Dilemma Through Lido Staking) https://www.wisdomtree.com/index/rtree (RWM WisdomTree Crypto Index) https://bitwiseinvestments.com/crypto-funds/bitw (Bitwise 10 Crypto Index) Our Sponsors https://www.veterinariansuccesspodcast.com/guardianvets (GuardianVets) (be sure if you reach out to mention us for 50% off your first month) https://www.veterinariansuccesspodcast.com/vetcheck-pet (VetCheck Pet Urgent Care Center Franchise)
As a dentist, how well do you know your insurance needs? Do you read the fine print? How often does price drive your decision when choosing a policy? Join us today as Scott Ruthstrom, CEO of Florida Dental Association Services (FDAS), and Carrie Millar, Director of Insurance Operations for FDAS, talk candidly about the topic and how their expertise helps dentists navigate through their insurance needs throughout the life of their dental careers.
Russia and Ukraine, Biden's Supreme Court nominee, and the FDAs updated dosage of a monoclonal antibody. Let's be informed so we can get on with our day.Support the show (https://www.buymeacoffee.com/thenewsdiet)
Rogue Retirement Lounge with Matt Franklin: Entrepreneur, Investor, Real Estate Enthusiast
Okay my friends, in today's podcast I'm probably gonna come off like a complete a-hole, but I can't help myself. I recently heard a podcast, hosted by a financial advisor, that had some really bad (in my opinion) information in it. Like, REALLY bad. But to prove that I'm not a total jerk, I wanted to promote three REALLY GOOD retirement planning podcasts that are hosted by financial advisors that I really like and trust: 1) Finishing Well with Hans Sheil https://podcasts.apple.com/us/podcast/finishing-well/id1345523361 (https://podcasts.apple.com/us/podcast/finishing-well/id1345523361) 2) Retirement Revealed with Jeremy Keil https://podcasts.apple.com/ca/podcast/retirement-revealed/id1488769337 (https://podcasts.apple.com/ca/podcast/retirement-revealed/id1488769337) 3) The Retirement Answer Man with Roger Whitney https://podcasts.apple.com/us/podcast/retirement-answer-man/id834314596 (https://podcasts.apple.com/us/podcast/retirement-answer-man/id834314596) Okay, after showing my nice side I get to dressing down this other podcast I listened to that was filled with (in my opinion) terrible information. One thing I do talk about is the great Fidelity report called "Bitcoin First." Here's a link to where you can view or download it: https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/bitcoin-first.pdf (https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/bitcoin-first.pdf) So as I mention in this episode, I'm really not doing this to be a jerk. It's not my style to hammer on some other dude's retirement podcast. And this will probably never happen again. I just wanted to point out that you need to VERIFY information. You need to do your own research. And most important, just because someone has a three-letter acronym after their name DOESN'T mean they know what they're talking about. And in defense of this kid, he's barely 30 years old, if that, so we can all give him a break for being young. Again, do your own research and take control of your finances. Remember, go to https://my.captivate.fm/rogueretirementlounge.com/crypto (rogueretirementlounge.com/crypto) to sign up for your own Blockfi account. You'll get up to a $250 crypto bonus and you'll be on the best exchange out there. AND you'll be able to earn interest on your crypto. And, you'll be supporting this show, as I'm a Blockfi affiliate! If you have a question you'd like me to answer on the podcast, email me at matt@rogueretirementlounge.com Check out more episodes at my https://www.rogueretirementlounge.com/ (retirement planning podcast) website: https://my.captivate.fm/www.rogueretirementlounge.com (www.rogueretirementlounge.com) Follow me on twitter! https://twitter.com/LoungeRogue (twitter.com/LoungeRogue) Follow me on Instagram! https://my.captivate.fm/instagram.com/lairdgrainger (instagram.com/lairdgrainger)
In this week's episode Jessie and Daniel discuss their experiences relaunching the CoolSculpting Elite technology after receiving news the FDAs 510k review has been approved. We're covering the changes made to the consent form, how this is helping our practice, and advise on how to market and relaunch the Elite news to your customer database. Whether you've invested in the newer technology yet or not, listen in as these safety updates are important to understand as ALL consent verbiage has been updated from the manufacturers. Ready to get started selling more CoolSculpting on Instagram? Don't miss out on our digital course on how we've successfully used IG to scale and grow our business. Learn more here: https://elementbodylab.com/enroll
This week on Look Forward, Jay and Brad return to discuss the full approval of the Pfizer vaccine, Mississippi has an idiot problem, Biden is sticking to his Afghanistan withdrawal timeline, the idiotic dynamic duo is back, right-wing sellout crown up for grabs, and much more. SHOW NOTES FDA gives full approval to the Pfizer COVID-19 vaccine Mississippi is having another outbreak...of stupidityFrom joke to very serious in a heartbeat Biden holding to 8/31 deadline despite criticism Two Congressmen perform an unnecessary publicity stunt...and for once it's not Republicans!Airlifts for you! Airlifts for you! Everybody is getting an airlift! The dipshit dynamic duo is back! THIS WEEK IN STUPID A good ole hometown story
Join the American Idiots this week as they delve into the hottest topics currently dividing our country. On the agenda this week another incident of a police officer kneeling on a citizen's neck has been uncovered. We will discuss the Mario Gonzalez incident and why it is not getting as much press as George Floyd. Also, this week Rep. Omar introduced a police accountability bill to the house floor. We will discuss what the bill is all about and what we think it means for the profession going forward. Finally, we will discuss President Biden and the FDAs' decision to ban menthol cigarettes. We will debate what kind of impact this can have on the tobacco industry as a whole. And of course what it means for individuals personal liberties and choices going forward. All this and so much more tonight on The American Idiots show at 7:30 PM CST.
Terry gives some insights into the FDAs racism. He also comments on wine and billionaires divorces. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app
Ric Edelman, founder of Edelman Financial Engines, and Matthew Kolesky, president at Arbor Capital, discuss the state of Bitcoin adoption amongst financial advisors, who control $5 trillion in investor wealth. In this episode, they talk about: their background and why they got into crypto (1:25) how most RIAs (registered investment advisors) view digital assets and the hassle of buying crypto on a client's behalf (8:59) what percentage of financial advisors have already invested in bitcoin and how many more will come into the space by next year (18:20) how RIADAC -- the RIA Digital Assets Council -- is educating financial advisors about crypto (21:59) their favorite methods to explain Bitcoin and other digital assets (25:22) the different ways financial advisors are getting bitcoin/crypto exposure for their clients (35:32) why RIAs use investment vehicles to purchase Bitcoin rather than spot-buying the actual asset (39:58) why GBTC is trading at a deficit to the bitcoin price and their thoughts on a bitcoin ETF (44:40) the percent allocation to crypto they feel comfortable with for their clients (54:26) how they rebalance crypto holdings, whether they use yield-bearing crypto products yet, and projections for 2021 (57:35) Thank you to our sponsors! Download the Crypto.com app and get $25 with the code “Laura”: https://crypto.onelink.me/J9Lg/unchainedcardearnfeb2 Indexed Finance: https://indexed.finance/ Episode links: Ric Edelman Twitter: https://twitter.com/ricedelman?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor RIADAC: https://riadac.com/ Matt Kolesky Twitter: https://twitter.com/mkolesky Arbor Capital: https://www.acminc.com/ + https://digital.arbor.capital/ Helpful Links: Bitwise ETF Trends + Survey of Financial Advisors https://static.bitwiseinvestments.com/Research/Bitwise-2021-Benchmark-Survey-Financial-Advisor-Attitudes-Toward-Cryptoassets.pdf Fidelity's Bitcoin Investment Thesis https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/bitcoin-alternative-investment.pdf RIADAC's 12 Predictions for 2021 https://www.thinkadvisor.com/2021/01/07/ric-edelman-12-predictions-for-bitcoin-other-cryptos-in-2021/ RIADAC 1% Allocation strategy https://riadac.com/digital-assets-are-now-mainstream/its-still-early-with-tremendous-upside-potential/ Arbor Capital's “True Digital Asset SMA” https://www.prnewswire.com/news-releases/arbor-digital-and-blockchange-partner-on-digital-asset-sma-for-registered-investment-advisors-301219459.html Grayscale BTC Premium Flips Negative https://www.coindesk.com/grayscale-negative-premium-bitcoin Blockchange https://blockchange.ai/
Ric Edelman, founder of Edelman Financial Engines, and Matthew Kolesky, president at Arbor Capital, discuss the state of Bitcoin adoption amongst financial advisors, who control $5 trillion in investor wealth. In this episode, they talk about: their background and why they got into crypto (1:25) how most RIAs (registered investment advisors) view digital assets and the hassle of buying crypto on a client’s behalf (8:59) what percentage of financial advisors have already invested in bitcoin and how many more will come into the space by next year (18:20) how RIADAC -- the RIA Digital Assets Council -- is educating financial advisors about crypto (21:59) their favorite methods to explain Bitcoin and other digital assets (25:22) the different ways financial advisors are getting bitcoin/crypto exposure for their clients (35:32) why RIAs use investment vehicles to purchase Bitcoin rather than spot-buying the actual asset (39:58) why GBTC is trading at a deficit to the bitcoin price and their thoughts on a bitcoin ETF (44:40) the percent allocation to crypto they feel comfortable with for their clients (54:26) how they rebalance crypto holdings, whether they use yield-bearing crypto products yet, and projections for 2021 (57:35) Thank you to our sponsors! Download the Crypto.com app and get $25 with the code “Laura”: https://crypto.onelink.me/J9Lg/unchainedcardearnfeb2 Indexed Finance: https://indexed.finance/ Episode links: Ric Edelman Twitter: https://twitter.com/ricedelman?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor RIADAC: https://riadac.com/ Matt Kolesky Twitter: https://twitter.com/mkolesky Arbor Capital: https://www.acminc.com/ + https://digital.arbor.capital/ Helpful Links: Bitwise ETF Trends + Survey of Financial Advisors https://static.bitwiseinvestments.com/Research/Bitwise-2021-Benchmark-Survey-Financial-Advisor-Attitudes-Toward-Cryptoassets.pdf Fidelity’s Bitcoin Investment Thesis https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/bitcoin-alternative-investment.pdf RIADAC’s 12 Predictions for 2021 https://www.thinkadvisor.com/2021/01/07/ric-edelman-12-predictions-for-bitcoin-other-cryptos-in-2021/ RIADAC 1% Allocation strategy https://riadac.com/digital-assets-are-now-mainstream/its-still-early-with-tremendous-upside-potential/ Arbor Capital’s “True Digital Asset SMA” https://www.prnewswire.com/news-releases/arbor-digital-and-blockchange-partner-on-digital-asset-sma-for-registered-investment-advisors-301219459.html Grayscale BTC Premium Flips Negative https://www.coindesk.com/grayscale-negative-premium-bitcoin Blockchange https://blockchange.ai/
En YT: https://youtu.be/K994HLyI2sk Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
1 de cada 2 de chilenos se trasladaría de país por trabajo En YT: https://youtu.be/GhYGIPOJd4g Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
En YT: https://youtu.be/2ROnBXaerMo Repasamos la respuesta del ejército de Chile ante incendio a estatua del general Baquedano suscitado el viernes 5 3 2021 Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
En YT: https://youtu.be/Fc-zYpDPsTQ Programa completo: https://youtu.be/l746z0FmawQ Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA
En YT: https://youtu.be/YdMpv0TQKOY Programa completo: https://youtu.be/l746z0FmawQ Actualización: https://www.emol.com/noticias/Economia/2021/02/23/1012988/Facebook-fin-bloqueo-noticias-Australia.html Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
En YT: https://youtu.be/qpwicdOMk0k Programa completo: https://youtu.be/l746z0FmawQ Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA
En YT: https://youtu.be/EcwhrOLoPO0 Programa completo: https://youtu.be/l746z0FmawQ Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
Programa completo: https://youtu.be/l746z0FmawQ En YT: https://youtu.be/QbNvJyHqGtU Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
Posteriormente la Corte Suprema revirtió este fallo salvo en 1 caso En YT: https://youtu.be/yOylL_6CyVs Programa completo: https://youtu.be/l746z0FmawQ Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
En YT: https://youtu.be/j-F4RS1K1Zc Programa completo: https://youtu.be/l746z0FmawQ Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
En YT: https://youtu.be/n4rfVZWghTc Programa completo: https://youtu.be/l746z0FmawQ Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.instagram.com/ProyectoChileOficial https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo Fuentes: #Tricel emitió fallo respaldando decisión del #Servel en el caso de candidatos a la convención constitucional de felices y forrados #Elecciones2021 https://www.latercera.com/politica/noticia/candidatos-a-convencion-constitucional-de-felices-y-forrados-no-podran-competir-en-eleccion-de-abril-tricel-emitio-fallo-respaldando-decision-del-servel/LNOLYTO2NRFENG5HDHCNYPGM4A/
En qué va el proyecto de ley que impide a los establecimientos educacionales, exigir a los alumnos, el uso de marcas comerciales determinadas en útiles escolares, de textos determinados y la entrega de útiles de aseo o artículos de oficina. En YT: https://youtu.be/lICgHJ9uFK8 Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
En qué consiste el proyecto de ley que establece un sistema de mensajes de alerta ante la desaparición de menores de edad. En YT: https://youtu.be/3Fg5AWUrFtg Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
¿En qué consiste el proyecto de ley que permite #restituciónanticipada de #inmuebles en #arriendos y comodatos? aprobado en la cámara de diputados de Chile En YT: https://youtu.be/kwFlRoYRXlo Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
La defensora de la niñez Patricia Muñoz presentó ante la Corte Suprema, su respuesta a la solicitud de remoción de parlamentarios oficialistas. En YT: https://youtu.be/2LZISPRCYIk Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
¿En qué va el proyecto de ley de voto anticipado? En YT: https://youtu.be/xdG_y4k4VA8 Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
Comisión de Ética del senado sanciona a Ximena Rincón por infringir la Ley de Lobby En Youtube: https://youtu.be/lMPf-KIAK04 Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
Senado de Chile aprueba en general norma que modifica la ley anti discriminación arbitraria En Youtube: https://youtu.be/dQAIOL6hk8Q Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
Ley de Migraciones, el Tribunal Constitucional (TC) resuelve acoger parcialmente requerimiento presentado por parlamentarios de izquierda (2/2) En Youtube: https://youtu.be/73JTmjVxvyM Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
Ley de Migraciones, el Tribunal Constitucional (TC) resuelve acoger parcialmente requerimiento presentado por parlamentarios de izquierda (1/2) En Youtube: https://youtu.be/DpSsXjbpvMo Redes: https://linktr.ee/ProyectoChile Puedes encontrar contenidos y fuentes de información del canal Proyecto Chile en: Canal de Youtube https://www.youtube.com/channel/UC5I-Fqn7so1vsvH4lMYqsGw Canal de Bitchute https://www.bitchute.com/channel/ojiB59iWxVU3/ Canal de Archive org https://archive.org/details/@proyectochile Puedes escuchar también contenidos de Full de Ases en Podcast. https://cl.ivoox.com/es/podcast-full-ases-el-podcast_sq_f1904469_1.html https://open.spotify.com/show/31apmbJ3QzkDykVI4mrShR https://podcasts.apple.com/cl/podcast/full-de-ases-el-podcast/id1510689131 Proyecto Chile es una propuesta en conjunto de: Comisionando Asuntos. https://www.youtube.com/channel/UC_FBKsjth0qYrHC_tH0HRkw Un Disidente. https://www.youtube.com/channel/UCxlVyzERJPLBfqVDdVSaCqQ Iracundo Tv. https://www.youtube.com/channel/UCppBGdzJkpteqPic4MxRhEA En RRSS: https://www.facebook.com/ProyectoChileOficial https://twitter.com/CanalProyecto https://www.facebook.com/IracundoOficial https://www.facebook.com/MisterIracundo
Christine Sandler, head of sales and marketing at Fidelity Digital Assets, talks about how 30 years in traditional finance and an early retirement led her to Coinbase, and, eventually, Fidelity Digital Assets. She discusses the history of Fidelity's involvement in crypto, how they became one of the first to enter the space, and what the future holds. Topics include: what Fidelity Digital Assets is and Christine's role there Christine's background in traditional finance, how she was drawn into the world of cryptocurrencies, eventually working at Coinbase, and how she found her way to Fidelity Digital Assets the role Fidelity sees itself playing in the digital asset space how the client base for digital assets has changed over time how Fidelity approaches the difficulties around explaining what bitcoin and crypto is, and the most common questions they receive how the pandemic has changed the conversation around digital currencies the types of services and products Fidelity is considering for the future the differences Fidelity sees in how international investors are approaching digital currency Fidelity's plans for a Bitcoin index fund and whether they are considering offering futures how financial institutions and institutional investors fit into a world of decentralized finance founded with the ethos of excluding them the regulatory improvements Fidelity is hoping to see what a Bitcoin ETF would mean for Fidelity how Fidelity might use a central bank digital currency in its business Fidelity's thoughts on offering proof of stake services whether a more deflationary Ethereum might attract more institutional investors and whether Fidelity will offer Ethereum in the future Thank you to our sponsor! Crypto.com: https://www.crypto.com Episode links: Christine Sandler: https://twitter.com/shoegalnyc Fidelity Digital Assets: https://www.fidelitydigitalassets.com/overview Twitter: https://twitter.com/DigitalAssets Christine leaves Coinbase for FDAS: https://www.coindesk.com/fidelity-poaches-coinbase-institutional-sales-head-christine-sandler Fidelity Center for Applied Technology: https://fcatalyst.com/overview Fidelity Digital Assets looking to become prime broker: https://www.theblockcrypto.com/daily/68920/fidelity-digital-assets-eyes-service-for-introducing-crypto-funds-to-big-investors How the client profile has changed: https://www.theblockcrypto.com/daily/42342/the-client-profile-is-changing-fidelity-digital-assets-exec-says-new-players-are-entering-the-crypto-fold How to Explain Cryptocurrencies and Blockchains to the Average Person Unchained episode: https://unchainedpodcast.com/how-to-explain-cryptocurrencies-and-blockchains-to-the-average-person/ Fidelity expands crypto business to Europe: https://www.coindesk.com/fidelity-to-expand-institutional-crypto-business-to-europe Fidelity obtains New York Trust Charter: https://www.coindesk.com/fidelity-gets-a-new-york-trust-charter-to-custody-bitcoin-for-institutions Bitcoin Index Fund: https://www.forbes.com/sites/michaeldelcastillo/2020/08/26/fidelity-president-files-for-new-bitcoin-fund/?sh=13aa335445c9 Fidelity survey of 800 institutional investors: https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/institutional-investor-study.pdf FDAS hiring: https://www.fidelitydigitalassets.com/articles/engineering-hiring-initiative?ccmedia=owned&ccchannel=social&cccampaign=hiring_blog&cctactics=twitter Kingdom Trust: https://www.coindesk.com/fidelity-digital-assets-to-custody-bitcoin-in-kingdom-trust-retirement-accounts
Christine Sandler, head of sales and marketing at Fidelity Digital Assets, talks about how 30 years in traditional finance and an early retirement led her to Coinbase, and, eventually, Fidelity Digital Assets. She discusses the history of Fidelity's involvement in crypto, how they became one of the first to enter the space, and what the future holds. Topics include: what Fidelity Digital Assets is and Christine's role there Christine's background in traditional finance, how she was drawn into the world of cryptocurrencies, eventually working at Coinbase, and how she found her way to Fidelity Digital Assets the role Fidelity sees itself playing in the digital asset space how the client base for digital assets has changed over time how Fidelity approaches the difficulties around explaining what bitcoin and crypto is, and the most common questions they receive how the pandemic has changed the conversation around digital currencies the types of services and products Fidelity is considering for the future the differences Fidelity sees in how international investors are approaching digital currency Fidelity's plans for a Bitcoin index fund and whether they are considering offering futures how financial institutions and institutional investors fit into a world of decentralized finance founded with the ethos of excluding them the regulatory improvements Fidelity is hoping to see what a Bitcoin ETF would mean for Fidelity how Fidelity might use a central bank digital currency in its business Fidelity's thoughts on offering proof of stake services whether a more deflationary Ethereum might attract more institutional investors and whether Fidelity will offer Ethereum in the future Thank you to our sponsor! Crypto.com: https://www.crypto.com Episode links: Christine Sandler: https://twitter.com/shoegalnyc Fidelity Digital Assets: https://www.fidelitydigitalassets.com/overview Twitter: https://twitter.com/DigitalAssets Christine leaves Coinbase for FDAS: https://www.coindesk.com/fidelity-poaches-coinbase-institutional-sales-head-christine-sandler Fidelity Center for Applied Technology: https://fcatalyst.com/overview Fidelity Digital Assets looking to become prime broker: https://www.theblockcrypto.com/daily/68920/fidelity-digital-assets-eyes-service-for-introducing-crypto-funds-to-big-investors How the client profile has changed: https://www.theblockcrypto.com/daily/42342/the-client-profile-is-changing-fidelity-digital-assets-exec-says-new-players-are-entering-the-crypto-fold How to Explain Cryptocurrencies and Blockchains to the Average Person Unchained episode: https://unchainedpodcast.com/how-to-explain-cryptocurrencies-and-blockchains-to-the-average-person/ Fidelity expands crypto business to Europe: https://www.coindesk.com/fidelity-to-expand-institutional-crypto-business-to-europe Fidelity obtains New York Trust Charter: https://www.coindesk.com/fidelity-gets-a-new-york-trust-charter-to-custody-bitcoin-for-institutions Bitcoin Index Fund: https://www.forbes.com/sites/michaeldelcastillo/2020/08/26/fidelity-president-files-for-new-bitcoin-fund/?sh=13aa335445c9 Fidelity survey of 800 institutional investors: https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/institutional-investor-study.pdf FDAS hiring: https://www.fidelitydigitalassets.com/articles/engineering-hiring-initiative?ccmedia=owned&ccchannel=social&cccampaign=hiring_blog&cctactics=twitter Kingdom Trust: https://www.coindesk.com/fidelity-digital-assets-to-custody-bitcoin-in-kingdom-trust-retirement-accounts
Trump pandemic, Dr Atlas pushes CDC to NOT test post exposure, FDAs rash push of plasma therapy, October Surprise?, comorbity vs cause of death, Dr Aaron Smith on covid risk factors
Trump pandemic, Dr Atlas pushes CDC to NOT test post exposure, FDAs rash push of plasma therapy, October Surprise?, comorbity vs cause of death, Dr Aaron Smith on covid risk factors
Boem! Bitcoin is an aspirational store of value! Dat je het ff weet. Boris, Aaron en Patrick van der Meijde van Bitkassa praten je bij over alles Bitcoin! De Bitcoin Show wordt mede mogelijk gemaakt door www.bitonic.nl Chat mee op https://t.me/debitcoinshow Volg ons op https://www.twitter.com/debitcoinshow Shell lijdt 15,4 miljard euro verlies in tweede kwartaal door coronacrisis https://nos.nl/artikel/2342276-shell-lijdt-15-4-miljard-euro-verlies-in-tweede-kwartaal-door-coronacrisis.html Duitse economie krijgt recordklap in tweede kwartaal: 10 procent krimp https://nos.nl/artikel/2342290-duitse-economie-krijgt-recordklap-in-tweede-kwartaal-10-procent-krimp.html America's economy just had its worst quarter on recordhttps://edition.cnn.com/2020/07/30/economy/us-economy-2020-second-quarter/index.html Fidelity: Bitcoin is an aspirational store of value https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/bitinvthessisstoreofvalue.pdf Ledger leaks https://www.ledger.com/addressing-the-july-2020-e-commerce-and-marketing-data-breach Samson Mow's Infinite Fleet ICO https://twitter.com/Excellion/status/1290537179014291458?s=20 A Miniscript based scripting language for Bitcoin contracts https://min.sc/ Bitmex grants 50.000 USD grant to jeremy Rubin to work on Judica https://blog.bitmex.com/bitcoin-developer-grant-provided-to-jeremy-rubin/ The Human Rights Foundation Awards Grants To Three More Bitcoin Projects https://bitcoinmagazine.com/articles/the-human-rights-foundation-awards-grants-to-three-more-bitcoin-projects It's LiT! Announcing Lightning Terminal: Your Home for Lightning Liquidity https://lightning.engineering/posts/2020-08-04-lightning-terminal/ The New Radical Documentary https://youtu.be/F-Us3DeNZLM
SUPPORT THE SHOW: LEDN offers Bitcoin backed loans – Sign up and get $50 free https://bit.ly/2CAZTZh NordVPN helps with your internet privacy – Get 70% off https://nordvpn.org/btcsessions Get Wasabi wallet and enjoy your privacy https://wasabiwallet.io/ MY ALL-ENCOMPASSING GUIDE TO GETTING STARTED WITH BITCOIN https://www.btcsessions.ca/post/how-to-buy-sell-and-use-bitcoin-in-canada Buy Bitcoin in Canada on Coinberry and get $20 after your first $50 purchase https://app.coinberry.com/invite/c5d52730857 Buy Bitcoin in Canada using Shakepay and get $10 for free after your first $100 purchase: https://shakepay.me/r/HUQFI60 If you value my work and would like to send me a tip, they are always appreciated! LIGHTNING tips: https://tippin.me/@BTCsessions Join my Telegram channel! https://t.me/btc_sessions SHOW RESOURCES: Bitcoin stock to flow model live: https://digitalik.net/btc/ Fidelity’s Bitcoin Investment Thesis https://www.fidelitydigitalassets.com/bin-public/060_www_fidelity_com/documents/FDAS/bitinvthessisstoreofvalue.pdf Ledger Data Breach https://www.ledger.com/addressing-the-july-2020-e-commerce-and-marketing-data-breach Support Bitcoin Devs through the Bitcoin Donation Portal https://bitcoindevlist.com/ Foundation Devices announces “Passport” Hardware Wallet https://foundationdevices.com/2020/07/introducing-passport/ TUTORIAL: Multisig using electrum https://www.youtube.com/watch?v=Sxo169CCfIc&feature=youtu.be BTSE Academy – Choosing A Mobile Wallet https://www.academy.btse.com/post/bitcoin-mobile-wallets BTSE Academy – Bitcoin Energy Consumption https://www.academy.btse.com/post/bitcoin-energy-consumption --- Support this podcast: https://anchor.fm/btcsessions/support
Matt and Nic review the stories of the week, featuring special guest Christine Sandler, head of Sales and Marketing at Fidelity Digital assets. Christine joins the show to discuss Fidelity's newly-released survey of institutional investor attitudes on digital assets. We talk about what FDAS is up to, client enthusiasm for the asset class, and how institutions are thinking about it today. Also covered in the episode: The Web3 dream – does it require blockchains? Bank Frick adds support for USDC Rebranding stablecoins to cryptodollars Bitcoin Billionaires is greenlit for a movie Other events in Bitcoin history which are movie worthy Three Arrows owns 6.26% of GBTC The fate of the GBTC 'premium trade' and the in-kind contribution Stephanie Kelton's NYT op-ed and unspoken constraints on MMT Coinbase is at a crossroads
Monologue Dr. Joel Wallach begins the show discussing mental health issues. Outlining several mental health challenges such as Autism. Contending they are all due to nutritional defciencies. Stating that if nutrients were put in the water these challenges would stop. Citing the Texas study where two counties were compared the numbers of violent acts. One county had a lot more vionet acts. But were missing a certain mineral in the water. The county with much less violence did have the mineral in it's water. Pearls of Wisdom Doug Winfrey and Dr. Wallach discuss a news article regarding the FDAs approval of Vascepa. The drug is touted to help prevent heart attacks, strokes and death in people with cardiovascular disease. Doc asserts that people should just Youngevity's EFAs. As the EFA Plus contains fish oils and are easily absorbed. Callers Venita has several health challenges including high blood pressure, weight gain and hypothyroidism. David has questions concerning a skin rash in his genital area. Roger is experiencing peripheral neuropathies in his hands and feet. Call Dr. Wallach's live radio program weekdays from noon until 1pm pacific time at 831-685-1080 or toll free at 888-379-2552.
Cigars for Warriors has released a press release regarding the impact of the FDAs regulation on premium cigars and how it will affect cigar manufacturer's ability to donate cigars to the brave men and women serving our country in the military. It describes the potential outcome if this regulation stands as is, and the steps being taken to ensure that our charity and others who give cigars to our troops continue to be able to do so. Follow us on Twitter: @stogiegeeks Facebook: https://www.facebook.com/stogiegeeks Instagram: https://instagram.com/stogiegeeks
Important new results of the FDAs investigation into DCM and grain-free diets. New training tech for dogs: haptic-style vests so you can communicate with your dog over long and noisy distances. GOATS! And what they’re talking about to each other, and how they’re feeling about it. And last, a new study into Snowball the dancing cockatoo and all his fly moves. Plus Eve answers some questions Efrem made up in a pure jet-legged mode! Do you correct someone who has their animals harness on wrong? What’s up with pet turtles in Lyon? Can you feed fish and birds bread? I mean, what could possibly go wrong?
Dr Carolyn Lam: Welcome to Circulation on the Run, your weekly podcast summary and backstage pass to the journal and its editors. We're your co-hosts. I'm Dr Carolyn Lam, Associate Editor from the National Heart Center and Duke National University of Singapore. Dr Greg Hundley: I'm Greg Hundley, Associate Editor for Circulation and Director of the Pauley Heart Center in Richmond, Virginia at VCU Health. Dr Carolyn Lam: So Greg, ever wondered if prophylactic use of ICDs would help prevent sudden cardiac death in dialysis patients? Well, guess what? We're going to be discussing it in the feature discussion of the ICD II trial coming right up. First, I hear you've got a very interesting probabilistic paper. Dr Greg Hundley: Yes. It's very sweet. This is from Renata Micha at Tusk University and it's examining the cost effectiveness of the US Food and Drug Administration added sugar labeling policy for improving diet and health. So Carolyn, in this study, investigators used a validated micro simulation US impact food policy model to estimate cardiovascular disease and type II diabetes mellitus cases averted, quality adjusted life years, policy costs, health care, informal care, and loss productivity in health related savings and cost effectiveness of two different policy scenarios. First, the implementation of the US Food and Drug Administration added to your labeling policy or just the sugar label. And second, further accounting for corresponding industry reformulation the sugar label plus reformulation. The models used nationally represented demographic and dietary intake data from the national health and nutrition examinations survey and diseased data from the centers for disease control and preventive wonder data base and policy affects in diet disease effects from meta-analysis and policy and health related costs from established sources. Probabilistic sensitivity analysis accounted for model parameter uncertainties and population heterogeneity. Dr Carolyn Lam: Sweet indeed, so tell us all about probabilistic analysis Greg. Dr Greg Hundley: Okay Carolyn, so between 2018 and then forecasting out into the future, so this is probabilistic, in the year 2037. The sugar label would prevent 354,400 cardiovascular disease cases, and 599,300 diabetes mellitus cases, gain 727,000 quality adjusted life years, and save 31 Billion dollars in net health care costs. Or 61.9 Billion dollars in societal costs incorporating reduce loss productivity and informal care costs and similar findings were accomplished for the sugar label plus reformulation scenario, both scenarios were estimated with greater than 80% probability to be cost saving by the year 2023. Thus, the results of this simulation exercises indicated that implementing the FDAs added sugar labeling policy could generate substantial health gains and cost savings for the US population particularly if the new label stimulates industry reformulation. The authors point out that the compliance date for updating the nutrition facts label including the added sugar perversion has been continuously delayed. And the authors believe, their findings highlight the need for timely implementation of this label so as to maximize health and economic gains. An excellent editorial was written by Elizabeth Magnuson at Saint Luke's Mid America Heart Institute revealing the strengths of this work and explains some of the variants that could occur in the results based on assumptions that were used in the authors micro simulation model. Dr Carolyn Lam: That is so interesting Greg, thanks. So from policy to guidelines and this time on cardiopulmonary resuscitation or CPR, now we know that an out of hospital cardiac arrest, chest compression only CPR has emerged as an alternative to the standard CPR where we use both chest compressions and rescue breathes. Since 2010, CPR guidelines recommend chest compression only CPR for both untrained bystanders and trained bystanders who are unwilling to preform rescue breaths. The current study really aimed to describe the changes in the rate and type of CPR perform before the arrival of emergency medical services doing three consecutive guideline periods with gradual adoption of compression only CPR and this was in Sweden. Now these were authors led by Dr Hollenberg from The Center of Resuscitation Science, Karolinska Institute in Stockholm, Sweden and colleagues and basically, they study all bystander witness out of hospital cardiac arrest reported in the Swedish register for CPR from 2000 to 2017. They found that there was a six fold higher proportion of patients receiving compression only CPR and a concomitant almost double rate of CPR before emergency medical services arrival, and these changes occurred over time. Any type of CPR was associated with doubled survival rates in comparison with cases not receiving CPR, and this association was observed in all time periods studied. They also found a small but significantly higher chance of survival after CPR with compression and ventilation in comparison with compression only CPR. Dr Greg Hundley: So Carolyn, does this mean we should go back to standard CPR? Dr Carolyn Lam: Well, remember these we observational findings, albeit really amazingly done and nationwide. But the findings really support continuous endorsement of the compression only CPR as an option and that's because its associated with higher CPR rates and overall survival of the no CPR skill. The authors ended up calling for randomized controlled trials, which are really needed to answer the question of whether or not CPR with compression and ventilation is superior to compression only CPR, especially in cases where bystanders have had the previous CPR training. Now, this is discussion in a wonderful editorial by Drs. Hsu and Neumar from University of Michigan Medical School. Dr Greg Hundley: Very nice, so you're going to tell us a little bit about troponin? Dr Carolyn Lam: Well, the question is "Is Plasma Troponin I measured by the high sensitivity assay associated with incident cardiovascular disease in the community?" Well, Dr Ballantyne from Baylor College of Medicine and colleagues decided to answer this question by looking at the ARIC Study participants age 54 to 74 years without base line cardiovascular disease and what they found was that elevated high sensitivity troponin I was strongly associated with increased global cardiovascular disease incidents in this general population, and this was independent of traditional risk factors. They also found differences between black and white individuals and between men and women. Dr Greg Hundley: What kind of differences? Dr Carolyn Lam: Well high sensitivity troponin I had a stronger association with incident global cardiovascular disease events in white compares to black individuals and a stronger association with incident coronary heart disease in women than in men. The authors also did a comparative association of high sensitivity troponin I vs. troponin T, they found that the high sensitivity troponins I and T show only moderate correlation with each other but were complementary rather than redundant in risk assessment for incident cardiovascular events in individuals without known clinical cardiovascular disease at base line. The bottom line is, adding biomarkers to traditional risk prediction models presents a potentially effective approach for future risk prediction algorithms for cardiovascular disease in the general community. Dr Greg Hundley: You know, think I might read that paper looking at that complimentary risk assessment. That sounds really interesting Carolyn. Well, I'm going to go back to the world of basic science and discuss a paper from Kun Wang discussing the long non encoding RNA regulation of cardiomyocyte proliferation and cardiac repair. Carolyn, post mitotic cardiomyocytes in the adult heart exit from the cell cycle and cease to proliferate, and that's the basis for their poor regenerative capacity and defective repair in response to say a myocardial infraction. Interestingly, the nonmammalian vertebrates such as our friend the zebra fish, their heart exhibits a robust capacity for regeneration. And it can efficiently regenerate its lost cardiac tissue throughout life due to this retain cardiomyocyte proliferation capability. Dr Carolyn Lam: Interesting indeed Greg about our friend the zebra fish. So what did the authors find? Dr Greg Hundley: Okay, in this study, Wang and associates investigated whether long non-encoding RNAs had a role in the regulation of cardiomyocyte proliferation and cardiac repair. Using bioinformatics and initial analysis, the identified a long coding RNA named Cardiomyocyte Proliferation Regulator or CPR that was comparatively higher in the adult heart as opposed to hearts in the fetal stage. The silencing of the Cardiomyocyte Proliferation Regulator or CPR significantly increased the cardiomyocyte proliferation in the postnatal in adult hearts, more over CPR deletion restored the heart function after myocardial injury which was evident from increased cardiomyocyte proliferation, improvement of myocardial function and reduce scar formation. Also, neonatal cardiomyocyte proliferation in cardiac regeneration where markedly suppressed in CPR overexpressing heart cells, therefore CPR acts as a negative regulator of cardiomyocyte proliferation and regeneration in fetal hearts. So, Carolyn the conclusion of this paper is that the inactivation or silencing of CPR accelerates cardiomyocyte proliferation along with significant restoration of cardiac structure and function after myocardial injury in adult hearts. And as such, further studies may investigate whether the therapeutic inter fashion of CPR could be a useful strategy to trigger the expansion of cardiomyocyte populations and myocardial repair. Dr Carolyn Lam: Nice Greg, so we've talked about CPR as in Cardiopulmonary Resuscitation to CPR as in Cardiomyocyte Proliferation Regulator, how about that? Well, that's as much as we go for now, let’s get to our feature discussion. Dialysis patients are known to have a high mortality rate, a large proportion of which have been attributed to sudden cardiac death and yet compared to patients with heart failure, these patients with dialysis have been either excluded or only nominally enrolled in all previous trials of implantable defibrillators or ICDs. Now that's why our feature paper this week is so important, and it is the Cardioverter-Defibrillator in the prevention of sudden cardiac death in dialysis patients that prospective randomized controlled ICD to trial. So pleased to have with us, the corresponding author Dr Wouter Jukema from Leiden University Medical Center as well as associate editor Dr Mark Link from UT South Western to discuss this very important paper. Wouter, congratulations, this is a very difficult, very important to do the study though, could you tell us a bit about what you did and what you found? Dr J. Wouter Jukema: Actually, you just referred to it as a very difficult study to perform and indeed it was. Many years ago, actually, twelve years ago, we noticed that now a lot of death in dialysis patients was attributed to sudden cardiac death, before we tried to make these type of patients better with all types of medications, but did not really work and suddenly the idea was, that came also from death certificates and death records that they have sudden cardiac death and we said we should monitor it and we should treat it in a prospective randomized study. We initiated the study after careful thoughts and we thought we would do it in 4-6 years but it took us 12. So it was quite an effort to set up this rightly and spread it around the Netherlands and activate a Nephrologist and a Cardiologist to take part in this prospective randomized controlled study in dialysis patients. Of course, you can easily imagine that you could have great benefit from this ICD devise, but you could also easily imagine that you would have complications of the implication of the device. So explaining that we should show it out, I think was the most important job we had to do and think that was a great effort, and it was not easy to do. Dr Carolyn Lam: And that in it of itself is very important observation. Dr Mark Link: So you picked patients without doubts, which is great I mean this is a difficult study, but you also picked with an LDF greater than 35% and traditionally, ICDs are indicated for under 35%, can you give us a little explanation on why you chose the greater than 35% population? Dr J. Wouter Jukema: Yeah, I think this is perhaps the most important remark on the study, because when we designed the study we had to choose at that time we had guidelines in general that under 35% of injection fraction you were entitled to receive an ICD, however of course almost never dialysis patients were included so there was no formal recommendation on that not to include them or not to exclude them, but dialysis patients have a death rate at that time to sudden cardiac death, anyway regardless of the injection fraction and we thought okay, the patient population that is first at high risk of sudden cardiac deaths so any dialysis patients but also they are entitled to have a meaningful extension of the lives because the prognosis of patients that are on dialysis with an injection fraction under 35% is in general so poor that it would be unfair to start there and most of the Nephrologists also would not allow it anyway, these patients are at the end of life and if you extended for two or three months its useless. Anyway, so we thought we'd pick the high-risk population and we prove that there were still on high risk but when we could do something meaningful to extend their lives, so we thought we do not pick the worst patients we pick the patients that we think we can really help. We screened them well, we treated them well and we see if an ICD on the patient will benefit them. And that's why we picked the over 35% rage. You need another study to do below 35%, but I don't think that our results are substantiating such an effort. Dr Mark Link: The population with EFs was 6-50%, which also has a high risk of sudden death in patients with dialysis but it’s still not looking with the population of less than 35%. Dr J. Wouter Jukema: No, I completely agree, and we acknowledge that in the manuscript, it was always in the manuscript within the revision that was also pointed out to us that it should be more clearly acknowledged, why we choose this patient population and finally, we can of course not make a formal recommendation on dialysis patients with an injection fraction of less than 35%. You can extrapolate data but we have no formal prof of course for this type of population. I fully agree. Dr Carolyn Lam: Before we go further, could you first describe, what did you find? Dr J. Wouter Jukema: Basically, the conclusions are the prophylactic ICD therapy in patients on chronic dialysis with an injection fraction of 35% or higher was not associated with a reduced rate of sudden cardiac death nor of all cause of mortality and besides that the preference of sudden cardiac death in this type of patients on dialysis was actually significantly lower compared to its reports from literature, so that's what we very often see of course if you fill out a death certificate, you have to fill out a cause of death and of course in many patients the heart stops, and you say it's a sudden cardiac death. But that's not what this study actually showed and finally it's also no authority that this population was not too healthy to see any benefit, if you look at the results over the years, then you'll see that after five or six years more than half of the patients are dead anyway, but due to all kind of causes and not to a sudden cardiac death. So, I think that this is from a pathophysiological background, this is also a very interesting study because we now have finally data, real data on sudden cardiac deaths in these types of patients. Dr Carolyn Lam: Indeed, and Mark, I know that you invited the editorial from Rod Passman, just discussing why did we see the results that we did. Not quite what we expected I suppose, what do you think Mark? Dr Mark Link: First, I want to congratulate Dr Jukema for finishing this study, this was a massive task and a difficult and long one. I think I was surprised, there has been reported to be a very high rate of sudden death in dialysis patients regardless of their LDF. The ICD is very good at preventing sudden deaths, but not good at preventing other types of deaths, so I would extrapolate to say, well you can prevent sudden death in dialysis patients, you should prolong their life and this study did not show that at all. And I was surprised, and it just goes to what Dr Jukema was telling us, that what's reported on a death certificate as sudden death is not necessarily sudden death and could be other types of death and at the end all death is sudden. Dr J. Wouter Jukema: I fully agree with that remark because that makes is cumbersome to have the right interpretation of the data, so you have to feel like something and then finally your heart stops. Dr Carolyn Lam: What seems that most of the reasoning seems to be maybe a lower rate of sudden cardiac death than we expected, but there were also other factors that were considered, for example, if you could clarify by dialysis did you mean both hemodialysis as well as peritoneal dialysis, do you think that made a difference? For example, do you think ICDs work differently in presence of uremic precipitant of arrhythmias vs. not and so on, what do you have to say about those factors? Dr J. Wouter Jukema: We include on purpose both types of patients, the peritoneal dialysis and the hemodialysis patients because you could easily in-visit that there could be a difference, for instance to fluid or electrolyte sheaths that are more sudden in the hemodialysis patients than in peritoneal dialysis and we did a sub-analysis where we looked at both types, but the results are essentially the same, it doesn't seem to matter a great deal of what type of dialysis you have, the amount of sudden cardiac is lowered and expected. By the way occasionally, of course the ICD did work in sudden cardiac death, was aborted. So, it’s not that the apparatus doesn't function it does, it takes it properly and if functions properly. But finally, it doesn't prolong the life and you will die of something else, mostly infections in general well-being when finally, the nephrologist will say this is end of life you have to stop the dialysis procedures anyway. Dr Carolyn Lam: Right, great points, now in the last few minutes, I'm dying to ask, what do you think of the next steps from here. Mark, what do you think first? And then perhaps I'll give the last word to Wouter? Dr Mark Link: I'll start with a question to Wouter myself, the question is what are we going to do now with the individuals on dialysis that are under 35%? I think this study has pretty clearly said that were not going to extend our CDs to people on dialysis with greater than 35%. But we still have a population that currently fits indication for a ICD if their expected longevity is greater than a year. And currently those people are included in the guidelines for ICDs, I think this study gives us some pause about what to do with our population. And many of that population are getting our CDs and I'd be curious to what Dr Jukema thinks about that population and whether that population warrants some randomized trial or whether we should continue with our current guidelines that recommend implantation of an ICD in any individual less than 35%, as long as their expected life span is greater than a year. Dr J. Wouter Jukema: I think these are excellent questions with excellent remarks, of course, finally, we do not know because we didn't investigate it, I can only imagine the difficulties we would have if we were to do a new additional trial with injection fractions patients less than 35%. I could tell you we had great great difficulty in persuading Nephrologists to take part in the study, because many of them were very reluctant, this is their principal, these are very ill patients, and a lot of them are more or less going towards the end of their lives so you cannot do this when we have Nephrologists telling us that they considered it an unethical study. A lot of them did not want to participate they said, "You shouldn't do this to this patient, they have troubles enough, they suffer from infections and all kinds of things." Having said this, I do not advocate that you should never implant an ICD in a dialysis patient, I think in our study we also clearly show that in dialysis patients, implantation of an ICD is feasible within acceptable although better complication risk and infection risk, so if you have a patient on dialysis where you feel this patient has a good life expectancy, for instance, he already suffers an episode of arrhythmia, I think you are entitled to discuss this with the patient and have it a try, it might work and prolong their life. So I would not say never do it, I think our studies show that you can do it, yes, it sometimes works but do not expect too much of it. You will never hear me say that in general you should not do it, if you have a clear indication for it you may do it, secondary effect may require a good reason, but primary prophylactic indication, that's a difficult one I think and to do this study in patients that are even more ill, with injection fraction of less than 35%, I feel will be exceeding the difficult. Dr Mark Link: One other comment I have is the issue of the SUBCU ICD I think changes the equation in a bit because the risk of infection is much lower with a SUBCU IDC in patients on dialysis, did you have any SUBCU ICDs in your study or was it all transvenous? Dr J. Wouter Jukema: We don't have any data, when we designed and the developed study, the such a device was not even there so we couldn't do that, and during the study we did not adapt that but of course there is also no formal proof yet that it's a lot safer, a lot better, and once again this time of subcutaneous ICD I think you can do it at an acceptable complication rate. But it’s not effective enough, it's not that the patients were dying from infections of their ICD, they were dying of all kinds of infections and malignancies. Infections due to the ICD were facing procedures, real complications were rare. Dr Carolyn Lam: Great! Thank you Wouter, thank you Mark, what an important study and what a lot of lessons that we learned here. Thank you very much audience for listening as well, you've been listening to Circulation on the Run, don't forget to tune in again next week. This program is copyright American Heart Association 2019
This paper is part of NMJ's 2018 Microbiome Special Issue. Download the full issue here. In this interview, naturopathic physician and probiotic expert Donald Brown, ND, discusses the role of probiotics in supporting the gut microbiome. Brown also describes the mechanisms of action and clinical applications of probiotics, as well as strains, dosages and potential contraindications. About the Expert Donald J. Brown, ND, is one of the leading authorities in the USA on the safety and efficacy of dietary supplements, evidence-based herbal medicine, and probiotics. Brown currently serves as the director of Natural Product Research Consultants (NPRC) in Seattle. He is a member of the Advisory Board of the American Botanical Council (ABC) and the Editorial Board of The Integrative Medicine Alert. He was a member of the Board of Directors for the International Probiotics Association (2008-2010) and its Scientific Advisory Board (2006-2008). He has also previously served as an advisor to the Office of Dietary Supplements at the National Institutes of Health. Brown is the author of Herbal Prescriptions for Health and Healing (Lotus Press, 2002) and was a contributor to The Natural Pharmacy (Prima Publishing, 2006), the A-Z Guide to Drug-Herb-Vitamin Interactions (Prima Publishing, 2006), and The Textbook of Natural Medicine (Churchill Livingstone, 2006). About the Sponsor Founded in 1979 by molecular geneticist Stephen Levine, PhD, Allergy Research Group® is one of the very first truly hypoallergenic nutritional supplement companies. For nearly 40 years Allergy Research Group® has been a leading innovator and educator in the natural products industry. Our dedication to the latest research about cutting-edge nutritional supplements continues to this day. Our purpose is to provide customers with products they can use to improve their patients’ quality of life, through scientific based innovation, purity of ingredients, education and outstanding service. ARG is proud to be a sponsor of the Clinical Education LinkedIn Forum, a closed peer-to-peer group on LinkedIn where healthcare professionals can ask clinical questions and receive evidence-based and clinical-based responses by experts in their field. Visit www.clinicaleducation.org/linkedin for more information & to sign up for free! Visit www.allergyresearchgroup.com for more information on ARG and our products. Transcript Karolyn Gazella: Hello. I'm Karolyn Gazella, the publisher of the Natural Medicine Journal. Today we are exploring the impact that probiotics can have on the gut microbiome. Before we begin, I'd like to thank the sponsor of this topic who is Allergy Research Group. My guest is naturopathic physician and a leading probiotic expert, Dr. Donald Brown. Dr. Brown, thank you so much for joining me. Donald J. Brown, ND: Hi Karolyn. It's a pleasure to talk to you. It's been a long time. Gazella: I know. Brown: How are you? Gazella: I'm doing great. I know. This is like old times. And you know, before we dig into this topic, I have to tell you that I am just fascinated by the human microbiome, and it seems like the research in this area has really exploded. Why is that? Brown: Well, I think, again, it's ironic as a naturopath talking about it because we've always talked about the impact that the intestinal tract has on health in general. Immune health, skin health, so forth and so on, and I think that what's happened is that particularly probiotic research has led us to realize that there's these microbes on our body. And we have a tendency in probiotics to focus on bacteria, but what's exploding in this area is that we have resident microbes that are viral microbes. We have fungal microbes that are natural inhabitants of our body. So looking at this, we're really talking about 40 trillion microbes, predominantly bacteria, and sort of the balance that we have with these microbes which are part of our body. And it's funny because the research [inaudible 00:01:54] dramatic, and we have 10 times more microbes on us and in us, mainly in us, than we have cells. And the new data is really indicating that that's not the case; it's about 1.3 to 1. So people who get itchy when they think that they have more bacteria on them than cells, it's not quite as dramatic as we thought. Again, I think it gets back to the fact that we're recognizing the fact that these things play such an interesting part in our health and our wellness, and when it tips in the wrong direction, our illness too. So expanding it out so we're not just looking at the microbes in the GI tract, but the microbes in other parts of our body as well. Gazella: Yeah, I think that's really some of the most interesting parts of this research is that it does expand beyond the intestinal tract. So as it relates to the human microbiome, remind us of the mechanisms of actions that probiotics have. How and why do probiotics even work? Brown: Well, probiotics ... When you think about the GI tract, the analogy I like to use, especially when I'm talking to the public ... talking to healthcare professionals here ... is it's sort of like a busy parking lot. And you have organisms that are health promoting, and then you have organisms that are potential pathogens, and they're looking for parking spots. Remember that bacteria ... viruses are the same way ... have to adhere to cells to be able to be either health promoting or disease promoting. So that's one of the first things that probiotics are doing is they're competing for spots. And once they actually set up house, they then start creating a micro-environment that is inhospitable to potential pathogens, producing things that are anti ... compounds that are antimicrobial. They alter the pH slightly to make it inhospitable for these microbes and really create a situation where, "Hey, this is our home. This is our neighborhood, and you're not welcome here" kind of a thing. The other thing that should resonate with most of the doctors on the phone is the whole idea of leaky gut and intestinal barrier function, too. It's one of the things that probiotics do once they set up house is they're also helping to produce mucin and to sort of keep those tight junctions in the intestinal tract, the cells healthy and intact. And that's very, very important. The other thing that they do is they also, in the colon, are producing short-chain fatty acids which are associated with reducing risk of cancer as we age. Production of short-chain fatty acids act to help with digestive health as well. And then one of the really interesting things that's really been discovered over the last, I would say, eight to 10 years, is that when these little bacteria actually bind, they're communicating through the intestinal wall with what are called dendritic cells which are funny-looking, little, sort of odd-looking starfish type things that send little feelers up through the ... into the epithelial cells. And the probiotics are actually communicating with them to sort of modulate the immune system. So they produce a little bit more of this, produce a little less of this. Inflammatory responses are also modulated through it. And then the last thing and one of the really, really interesting things right now is we're beginning to realize that the intestinal tract is communicating with the brain. So the gut-brain axis is what that's called, and we know that stress, for instance, can actually negatively impact the probiotics in the GI tract, the healthy bacteria in the GI tract, and in turn, through the vagal nerve going up to the hypothalamic-pituitary axis, actually modulates that response. So we're now finding out that probiotics may actually be involved in ... I'm sure you've done interviews where you talk about the HPA axis and stress response. We're now finding out that the GI tract is very, very directly involved in that. So it could be negatively impacted by stress but can also positively impact the HPA axis, which is a whole new mechanism of action which is wild. So we've got gut health, digestive health. We have immune health based on responses with the GI tract. Now we're finding out that there's actually effects on mood, stress response, that sort of thing. And that's not even covering the female genitourinary tract which has its whole population of probiotics that are positively affecting genitourinary tract health as well, so it's big. It's a vast influence on the body. Gazella: Yeah. There is a lot going on here with probiotics. I think that's why I like the topic so much because there's just so much to talk about. So when we're looking at the scientific literature and the research, what conditions have the most compelling research in terms of improved outcomes? I realize that this may be a pretty long list, given the mechanisms that you've just described, but take us through that list from a research perspective. Well, I think what I like to do is I like to start with the things that are accepted by the larger medical community. And one of those is the fact that we've known for a long time that probiotics have a positive effect on prevention of antibiotic-associated diarrhea. So I would put that probably at the top of the list of, hey, if I'm in a room and I've got people who are skeptical of alternative medicine, integrative medicine, that's always a good starting point because we have really solid data that antibiotics definitely are good at preventing that. My background is in pediatrics, and I think another area that has sort of reached a critical mass is actually ... it's fascinating ... is the prevention of atopic dermatitis in children who are potentially at risk. The studies started ... First one was in the Lancet in early 2000s, and basically the studies are looking at mom particularly but also whoever the partner is, and risk of ... that have a background of atopic diseases, allergic diseases, and actually starting to give mom probiotics during the second half of her last trimester. And then once the baby is born, if mom's nursing, continuing to give the probiotics to the mom until she stops. And then, anyway, it varies on the study, but usually then the infant starts to take the probiotics. What they're finding is that it's reducing the incidence of atopic dermatitis by about 50%. That's amazing to me because if you look at sort of tracking the use of the antibiotics in children on a graph and you look at the increase in atopic diseases, so you're looking at eczema, atopic dermatitis. You look at asthma. They track almost exactly if you look at from 25 years ago to now, they track almost exactly. And also cesarean births contributing to that as well where the microbiome, so that's really fascinating to me. I would say the other area, sort of shifting gears, that I think has reached a critical mass is also adjunctive use of probiotics in female genitourinary tract health. So treatment using standard treatments for things like bacterial vaginosis would probably be the top area, but also prevention of recurrence of urinary tract infections. We're, particularly in the bacterial vaginosis area, I think really reaching a point where we have enough data to sort of suggest that, hey, using these things really can help with prevention. And then I would probably put the last one, as we move into the immune system and we really have reached a critical amount of data. Not a lot of pediatric data but adult data now that suggests that routine use of probiotics seems to reduce the incidence of upper respiratory tract infections. So, again, I could go on and on and on. Gazella: Right. Yeah. Brown: There's a lot of stuff. There's a lot of stuff that's emerging and that we're sort of on the edge. But one of the things I think the listeners need to know about is the fact that I think we like to think about alternatives too, but one of the great things about probiotics is that adjunctive use. Obviously it's antibiotics, but Helicobacter pylori, for instance. The standard treatment of that is very rough on people. Recurrence rates are really high, so one of the themes that I always like to talk about when I talk in my lectures to healthcare professionals is that remember that a lot of the treatments that we use for ... Let's take urinary tract infections. E coli are really good at setting up what are called biofilms that are these little bits like taking a Visqueen sheet and putting it over themselves so that you can get to use the antibiotics. You can get to the ones that are not underneath the protective shield, but the ones that are under there don't get affected. So one of the things that probiotics are great about is going in and helping to break up that biofilm and actually make standard treatment perform better, and then continuing to use the probiotics actually reduce recurrence rates. So, and there's reduced recurrence rates, and there's a whole litany of examples of areas where if we use probiotics. I mentioned helicobacter pylori but also UTI's, bacterial vaginosis, where probiotics actually help the treatment go better, outcomes are better, and then really reduces recurrence rates. Gazella: Yeah. That's such a good point and you know, you mentioned antibiotics and how they disrupt gut flora and how probiotics can help reverse that dysbiosis. Are there other medications that kind of do the same thing as antibiotics where they disrupt that gut microbiota diversity and that probiotics may be able to help reverse that? Brown: We're thinking that some of the more aggressive inflammatories that people take may have an affect. That's still sort of in the early phases. One of the early ones, interesting ones that there's still a limited amount of data, but I actually reviewed it, was a study with a proton pump inhibitor, so things that we're using for reflex and that sort of thing, having a very negative effect on the microbiome. So, we're sort of still in the early stages of learning what specific drugs and the effects are. Obviously antibiotics would the be the easiest case study, because we can actually look at the what affects. They've done studies with people who are getting the triple therapy for helicobacter pylori and realizing that during that therapy, the healthy bacteria in the G.I. tract can be reduced by as much as 80%. If we use probiotics, during that treatment, it reduces that to 40 to 50% and then if we continue to use it after, people tend to bounce back quicker. There are other drugs that we know are beginning to emerge that have negative effects, but stay tuned on that one. Gazella: Right. Right. Now, let's switch gears and talk little bit about strains, because I know that that's a hot topic. So, specifically for the conditions that you mentioned in helping to restore gut microbiota that's been disrupted by medications like you were just talking about, what are the more common strains used for these types of clinical applications? If you don't mind my backing that up, I am very, very disturbed when I hear people lecturing who say that strains don't matter. I go to a lot of international conferences. I sit on committees that set standards, international standards for probiotics and it is something that experts who know a lot more about this area than I do are upset about, because there are people out there who are saying that it's species specific and strains don't matter. I beg to differ. I think that it's very, very important that health care professionals realize that, particularly health care professionals realize that ... and Karolyn, you've known me for a long time. We've done interviews about [bontanical 00:16:20] medicine that I'm an evidenced based person. I like to see the ... particularly if we're talking about treating a condition. And so when we go from species level where there's very little research to strain level, we emerge into an area where we know what the dosage was, that was used in the study. Particularly when we talk about pediatrics, we talked about people who might be immune compromised. We talked about older folks like myself. It's important also to ... safety is pertinent too and that's one of the areas that is a little bit of a red flag for me with the whole probiotic area. Particularly on the commercial side where we have this race to do all these different things and some of the species level stuff that's being sold has not been clinically studied. And so, very, very important that people realize that some of the standards that go around a strain or viability is the lack of bacillus or the bifidobacterium strain that you're using shown to be viable. Does it actually adhere in the intestine is one of the things that we now have the ... within the persons body, but we now have technology that can actually show that these things sort of do adhere, and how long they adhere, and how long they stick around. Another thing that's really important that I've given many lectures to health care professionals is they don't think about is that we also don't want these strains, what's called trans located, we don't want them to go from the intestine to the blood stream. And they're having case studies. There was a paper published a number of years ago on people who were really severely immune compromised where the probiotic that was being ... it was a specific strain actually trans located into the blood stream and caused sepsis. People then had to be treated with very aggressive antibiotics. So, we don't want them to go from the intestinal tract into the blood stream. Another one that's [inaudible 00:18:39] ... we're talking about antibiotics, I always chuckle when I remiss on this one is also we realized that hey, probiotics are good for people who are taking antibiotics, but we also want to be sure that the probiotics strain has been tested for not blocking the ability of the antibiotic to do it's job. So, it's called antibiotic resistance. And it can be transferable. They have run into organisms that we think are probiotics that actually have a negative effect on an antibiotic doing it's job, so that's important. I already talked about safety and efficacy. I'm all about that. A silly one that I just want to toss in that's talked about internationally, that I still bump into in the U.S. more so than in other areas is the fact when we talk about being a probiotic supplement, we want to look at the label, and we want to be sure that these stability, or the shelf life of the product is actually been proven to the time expiration. There are still a lot of probiotic products that are sold in the United States that actually declare their potency at the time of manufacture, which is like, well okay, but I have a vitamin C product. They told me the potency when it was manufactured, but it says it has a two year shelf life. Have they actually tested that? Has that actually been proven? And so, remember, these are living organisms. Very, very important that stability or shelf life be proven for these as part of the choice of picking a supplement. Gazella: Well, I was just going to say, do you have some go to strains that you like to focus on when it comes to recommending probiotics? Brown: I think there's a lot of them right now, actually. That's another area where we could probably go on and on about. There are what I like to call legacy strains that have been around for a while that have a lot of research on them that have ... and we also understand their mechanism of action really well. The one that people probably know the most is lactobacillus GG, which is a rhamnosus strain that was discovered by a couple of guys in Boston. I always like it when they give their own name to the strains. It was Gorbach and Goldin I think were their names, so they named it lactobacillus GG. But anyway, that one has been around for a long time. A lot of really, really excellent research. Some of the bifidobacterium strains from Japan from [Morinaga 00:21:24] is the name of the company, have a lot of research, particularly in the pediatric area. Been around really since the ... lactobacillus GG, since the early '60's, the Morinaga [inaudible 00:21:38] really since the '50's. The Japanese were doing isolation in human studies long before we were doing them here in the U.S. Brown: Another one that I really like is lactobacillus acidophilus DDS-1. It's an interesting strain that was discovered by a guy named Dr. [Shahani 00:21:56]. By the way, all of these strains that we're talking about are derived from humans. These are human derived strains and this one was actually discovered and isolated first in 1959. And like the lactobacillus GG and some of the Morinaga strains has a lot of clinical research. It also ... in vitro research that shows that it adheres, that it survives. And then human trials, actually looking at it's ability to treat things like travelers diarrhea, prevent antibiotic associated diarrhea, those sorts of things. When I look at products, I always look at what's the indication? What's been studied? There's commercial strains the lactobacillus, I'm sorry rhamnosus HN001, for instance, in the atopic dermatitis prevention area that has phenomenal studies. And so there are a number of strains out there that have reached that critical point of whether its specific to one condition or have been looked at in other areas that have really excellent data. And again, being somebody whose background was in pediatrics, I'm always also looking at what's your safety data as well. That would be an example of a few strains that I think have really excellent data. Gazella: Yeah. That's good. And you know, not that long ago, we were seeing maybe just one or two species, one or two strains. Now we're seeing multi species, multi strains in these formulations, sometimes six, nine, twelve different species or strains in one formulation. Is that a good thing? Brown: Sometimes it's a commercial thing. Here's my theory and I could easily be misproven [inaudible 00:23:58], but or unproven. Are you misproven or unproven? Which- Gazella: I'm not sure. Brown: Called out for my lack of proof. My answer to that, when I get asked that, and it's more common when I'm lecturing to the public or to managers of supplement sections is that probably for wellness purposes. So if I'm taking a probiotic or if I'm a doctor and I'm recommending a probiotic supplement to be taken daily, I probably would use something that's a little bit more of a multi strain. Sort of a balance between the lactobacilli family and the bifidobacterium family. That's a sort of my go to. And as you get into the senior population, seniors have a tendency to have a drop in the bifido. That's probably dietary related, because fiber and that sorts of things, they like to feed on ... They're probably eating less fiber in their diet. But anyway. Having a balance of a number of strains, is there a magical number of strains? I don't think so at this point. I don't think anybody's proven that. I think the difficulty ... what I say to people is, is that when you shift, it's much easier to talk about a single strain or a combination of a couple strains. You know, in irritable bowel syndrome, inflammatory bowel disease, BSL-3 has eight different strains in it. I mean, that's a lot of strains. It's been around for a long time. They use very high doses, but its easier to look at disease endpoints when we do a clinical trials, because we have very clear outcomes that we're looking for compared to what's a placebo, for instance, Wellness studies are really hard to do, so I don't know that there's an easy answer to your question because I don't know if the company after I ... know a lot of them, and some of them have a lot of ... have deep pockets. I don't know who's gonna do a wellness study that shows that, "Hey, if you do this many strains at this potency, that it works better than if you only do one strain at this potency, or if you do nothing." 'Cause those are expensive studies to do. Gazella: Yeah. Totally. And I'm gonna ask you another unfair question, and it's regarding dosage. You know that can be somewhat controversial, still debatable. How do you dose probiotics or recommend ... What's your philosophy on the dosage? Brown: Well, I always start with what is the clinical. If I'm treating a specific condition and I'm using an evidence-based strain I dose it at the dose. And it's interesting, 'cause there's extremes and that's one of the issues when we look at meta-analyses that have been done, so stuff like say, not only was there this cacophony of strains that were used, going from one strain to five strains. That sort of thing. But the dose, the potency and we measure the potency of probiotics, what are called colony forming units so we talk about milligrams or gram amounts of these things. So I always try to look up with what the research showed. Again, leading back to wellness and sort of, regular use. I have a patient who's take a multi-vitamin, who's taking fish oil every day and I say, "Hey, one of the things you should think about is keeping your intestinal tract healthy and probiotics are gonna contribute to that, keeping your immune system healthy." I don't have an easy answer for that. I typically use multi-strains and I'll probably usually go in the 10 to 50 billion CFU per day. Is that correct? Is there clinical data to back that up? The answer is no, I don't know for sure. But that's sort of how I think. The one thing that I can tell you is that I remember a client who decided to go high potency and high potency is definitely [inaudible 00:28:23] was like 25 billion CFUs per instance, it was like a shot across the balance. It was 12 years ago. And I'm freaking out because [inaudible 00:28:33]. You can't go run 5 billion CFUs per day or people gonna be having a [inaudible 00:28:41] reaction or getting thrown out of dinner parties 'cause they're farting and having to go to the bathroom all the time. So what I can tell you is that we have enough data now in healthy people that if we go to, even, 100 billion CFUs per day that we're not seeing any adverse effects. We're usually with this ... How much of that is actually ... adhering how much of it is actually having an impact versus 40 billion, 50 billion or even 10 billion for that instance. So that's another one that's gonna be interesting to see how that evolves. There's obviously, particularly on the retail side in this race to see who can come out with the highest potency with most strains and we'll see how that goes. Gazella: Right, yeah. Well, I think that was a difficult question and you answered it brilliantly. So now it seems like many probiotics on the market are actually synbiotics because they combine pro and prebiotics. Now, what's your view about this combination and why are more companies going in that direction? And am I right, are companies going in this direction? Brown: Well, here's my criticism of that and I like synbiotics. I think the whole concept is an interesting one. On the retail commercial sense, it's been difficult for consumers to wrap their head around a probiotic and then also there's this concept called prebiotics and then again for people who are listening, a prebiotic is basically something that acts as a food for probiotics to feed on and grow and encourage growth even on their own. The issue that I have with a lot of products that combine probiotics and prebiotics, whether it's FOS, GOS, XOS now is another one that's used. Now these are basically complex sugars. Really, for all intents and purposes, kind of fibers. All of the FDAs now said that they are probably not gonna qualify to make the cut. The problem is that if you look at the studies on the prebiotics, the dosages are way higher than what you're gonna put into a capsule. There are some probiotic products that I've seen that have ... that are powders or that are in the sachets where you can actually get the prebiotic up to a dose that actually has any meaningful effect clinically. So remember with prebiotics, we're rack out a low of a gram and many of the studies were as high as 10 to 15 grams. So again, really important to sort of ... And I know this is a challenge for people who are in clinical practice because they're trying to treat some patients with what they think is the best, but it's really an issue of, again, getting back to sort of ... Does the company make an attempt to sort of match up the dosage of the prebiotic that actually showed an effect, a positive effect on probiotics? And that's a challenge. That your delivery yet [inaudible 00:31:50] in capsules, it's under dose. You don't get enough of the prebiotic. Gazella: Yeah, that's really interesting because I was not aware of that. So, that's a good heads up there. Now you talked about safety, but are there any contraindications that clinicians should be aware of? Direct contraindications that says, "This patient should not be on probiotics"? Brown: The area that I'm most cautious about ... I used to think it was premature infants, very low growth weight infants, but there's been enough research. When you ask, probably why the other thing too, that would be our [inaudible 00:32:24] list of things that have really reached critical masses, prevention of what's called Necrotizing Enterocolitis and in very low growth rate entrance ... fascinating and it worked. It's basically saving lives is what we are talking about. The death rate from that is quite high. So used to saying, "Hey, these kids are born ... GI tracts not really developed." That's a potentially dangerous use in that population. The answer to that is "No, actually. It's actually good." I would still continue to encourage on healthcare professionals to be very selective in strains that they use in people ... HIV positive, AIDS, people with really severe immune deficiencies. Cancer patients who ... technically more advanced cancer. Be very selective and try to get to the best of their possibility, look at the data and say, "Okay, this is strain that actually was used in that population and works." That would not ... Those two populations are ... that collection of population severely immunocompromised people is not one that I could, probably just use any probiotic supplement. Particularly multi-strain, high potency without doing any sort of research. I'm very selective and usually do one strain or two strains in that population that I feel have enough safety data. Gazella: Yeah, that's good advice. Anything else that you'd like to add on the topic of probiotics for listeners that you'd like to leave them with? Brown: Again, I just think that it very, very important to first and foremost, and I'm repeating myself. First and foremost look at if you're using it for specific use. We didn't even get into female genital urinary tract health nursing. Really amazing stuff going on in that area. Your oral use of probiotics to actually, finding that they're populating in the vagina and that you're getting significant effects, which is amazing. We used to think you'd have to use everything with ... through a vaginal, pessary type of an effect. So that's it. I think again, trying as much as possible to deal with companies that are trying to ... that are working with strain suppliers or strain suppliers that are manufacturing products for them that are looking at the essentials that we talked about at the beginning. It's really, really important to me. And also again, trying to insist that companies refer back to the data on specific strains as opposed to just saying "It doesn't matter, you can use anything you want." I'm horrified when I go to professional lectures and I hear ... For instance, medical doctor getting up and saying that it's [inaudible 00:35:14]. So it goes against every thing that is accepted in the probiotic world. So, again, a lot of white noise in this area. Healthcare professionals are going to be as susceptible to it as consumers are but that's a couple of areas where I think you can sort of cut through that and try to get to what really has been shown to be effective and safe. Gazella: Yeah. I mean, it's a big topic for sure. We're going to have you back to dig in a little bit more deeply on some of these topics, but I want to thank you for definitely shedding some light on this important topic, and helping us get through it. And I'd also like to once again thank the sponsor of this topic, who is Allergy Research Group. So Dr. Brown, thank you again for giving us all this wonderful information and I hope you have an awesome day. Brown: Thank you Karolyn.
How good is the body of evidence surrounding the recent FDA warning on general anaesthesia in under 3's? Derderian CA, Szmuk P, Derderian CK. Behind the Black Box: The Evidence for the U.S. Food and Drug Administration Warning about the Risk of General Anesthesia in Children Younger than 3 Years. Plast Reconstr Surg. 2017 Oct;140(4):787-792.
In this episode we discuss: E-Juice Review: Black Note Forte Quick Vape News From Around the World New York Lawmaker Wants To Ban E-Juice Flavors Old School Vape Review: 454 Big Block RDA Johnson Creek: Longest Running E-Juice Company Goes Out Of Business UK's Next Day Battery Found Selling Fake Chargers The FDA Released Their Final Guidelines on Free Samples of Tobacco Products Show notes can be found on this episode's page on VapePassion.com Subscribe to the VapePassion YouTube channel --- Support this podcast: https://anchor.fm/the-vapepassion-podcast-vaping--electronic-cigarettes/support
Today, Steve interviews of CEO of Vivio Health Pramod John. This company is re-inventing the supply side of the specialty drug industry. Out of control healthcare costs are the single biggest threat to the US Economy, set to rise by $70 Million dollars PER DAY! Steve and Pramod discuss: The political process and healthcare consumerism Health insurance vs. Health Drug pricing...is where you 'pick it up' Major misunderstandings of the FDAs true role A disruptive model (without a PBM) to get consumers and companies the most effective drugs at the best prices.
John is a husband, father to four, small farmer, author, and speaker. After serving on the board of the Farm-to-Consumer Legal Defense Fund, he was asked to serve as interim Executive Director and now full Executive Director. John has participated in the small farming and food freedom movement in many ways over the years, serving as administrator for one of the largest local food buying clubs in the nation (Whole Life Buying Club). He acted by standing up with the members of that buying club to unjust enforcement actions that denied them access to real food, protesting the FDAs harassment of farmers and consumers seeking real food. John regularly speaks across the nation on matters related to food, health, and farming. He and his family steward the 35 acres that they like to call Some Small Farm. John and Greg have an eye-opening chat about the rights of farmers and growers in America. Listen in and learn about: His unlikely path to where he is now, from a junk food eating video game junkie teenager to the highly active advocate for real food and farmers What health issues arose due do his eating lifestyle Why he was motivated to shift his mental view of himself and the world The CSA adventure that he took with his wife that developed over time The unbelievable examples of intervention that are now motivating his participation in the food movement Why he believes the government is involved in the food and agricultural industries How food regulation is being used in ways that we did not originally plan How his organization is working to help small farms and farmers How he included a warning with his marriage proposal How his buying club stood up to the State Health Department What rights are available to farmers and growers who are being told what they can sell and to whom Some of the issues that raw milk farmers have dealt with and the help that is available How milk is key to the alternative food system What services the Farm-to-Consumer Legal Defense Fund offers How to join the the Farm-to-Consumer Legal Defense Fund if you are a farmer, a homesteader, or just an interested person. And a lot more Go to our Podcast page at www.urbanfarm.org/blog/podcast/ to find photos, links, and more information on this podcast, as well as for each of our other great guest interviews. You can also sign up for weekly email summaries of the interviews.
In this podcast, Derek Smith discusses the possibility of medical devices being hacked and the FDAs guidance on how to deal with such a threat. Derek A. Smith Biography Derek A. Smith is the Director of Cyber Security Initiatives at the National Cyber Security Institute at Excelsior College. Mr. Smith has years of government and military leadership experience and holds an MBA, Master of Science in Information Assurance, Master in Information Technology Project Management, and B.S in Education. He also holds the following certifications: Certified Information Systems Security Professional (CISSP), Certified Authorization Professional (CAP), Certified Ethical Hacker (CEH), Certified Hacking Forensic Investigator, Computer Network Defense Architect, Certified EC-Council Instructor, Certified SCADA Security Architect (CSSA), and Security+.