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The DORA organization is dedicated to helping others build software better and faster, at a higher quality, and in a way that is more efficient. They continue to compile and publish the Accelerate State of DevOps report every year, which is a fascinating read. As a part of the report, they have identified four key metrics that identify high performing organizations in terms of software. These are divided into two areas: throughput and stability. Throughput measures are change lead time and deployment frequency. Stability measures are the change fail percentage and failed deployment recovery time. Read the rest of Database DevOps Metrics
In this episode of the Hydrogen Innovators podcast, we welcome Jimmy Rojas, founder and CEO of Evoloh, an innovative company transforming hydrogen production through advanced alkaline electrolyzer technology. Jimmy shares his journey from academia to entrepreneurship, highlighting how Evoloh uniquely reduces hydrogen production costs by using standard, high-throughput manufacturing techniques and 100% domestic supply chains. He explains Evoloh's strategy of focusing exclusively on stack production, designed explicitly for compatibility with low-cost, commercially available equipment, drastically cutting the cost of hydrogen. He dives deep into the challenges of electrolyzer manufacturing, global hydrogen markets, and the importance of flexible load-following technologies for renewable integration. Tune in for insights into Jimmy's leadership philosophy, inspired by fostering growth within his team, and hear who personally motivates him in his remarkable career. A must-listen for anyone interested in the future of green hydrogen and cleantech innovation.
EIP-7691: Blob Throughput IncreaseIncrease the number of blobs to reach a new target and max of 6 and 9 blobs per block respectively.Resources: ----------------- Presentation: Google SlidesOther Resources: - EIP-7691 - DiscussionUseful Links from Meeting: - Contribute to Xatu Data - Mainnet Client Split - Formalize Hardware RequirementsVideo Playlists: - Pectra PEEPanEIP Playlist - PEEPanEIP PlaylistFollow on Twitter: -------------------------- - Sam Calder-Mason - Parithosh Jayanthi - Toni Wahrstätter - Pooja Ranjan --------------------------Edited by: Akash KshirsagarTopics Covered: ------------------------- 00:00 - Quick Recap 00:27 - PEEPanEIP Intro 00:41 - Introduction 01:20 - About EIP-7691 02:28 - Parithosh Introduction 02:48 - Sam Introduction 03:12 - Toni Introduction 03:43 - Presentation Start 03:43 - Presentation by Parithosh 03:58 - Why Scale Blobs? 05:28 - What Are the Blockers? 06:51 - Non-finality Events 08:31 - Devnet Setup 10:40 - Meme by Parithosh 11:06 - Learning 15:06 - Conclusions 18:27 - EIP-7742 & EIP-7840 19:31 - Presentation by Toni 21:44 - Reorg Share Over Time Chart 24:30 - Presentation by Sam 24:32 - Finalizing EIP-7691 24:44 - Deciding Parameters 25:07 - EIP-7691 Impact 25:36 - Home Stakers 26:22 - Community Contribution to Xatu 27:11 - Post: Block Arrivals 27:37 - Why 6/9? 30:17 - Presentation End 31:48 - Post Presentation Talk 33:19 - Q&A Section 33:29 - Reorg Chart Related Question - Does the Number of Participants Affect the Reorg Chart in Any Way? 35:16 - Do We Expect EPBS and ILS Proposals to Streamline Better? 35:58 - Are There Any Risks or Concerns With Increasing Blob Throughput? If So, What Are They, and How Does EIP-7691 Mitigate Them? 37:45 - What Monitoring Tools and Data Indicate the Network Can Safely Scale Up? 40:34 - Are There Any Bounties for Tool Providers? 41:11 - How Does This Proposal Fit Within Ethereum's Long-Term Scaling Roadmap, Especially With Upcoming Improvements Like PeerDAS? Should Infrastructure Providers Start Preparing for Further Data Availability Upgrades? 44:28 - What, if Any, Changes Should L2 Teams and Infrastructure Providers Make to Take Advantage of Increased Blob Throughput? 47:39 - How Can Anyone Contribute to the Discussion? 49:43 - Rapid Fire Section 50:04 - Rapid Fire With Parithosh 52:14 - Rapid Fire With Sam 53:33 - Rapid Fire With Toni 55:07 - Pooja Closing Words------------------------- #EIP7691 #Ethereum #PEEPanEIP #Pectra
The Automotive Troublemaker w/ Paul J Daly and Kyle Mountsier
Shoot us a Text.We've got good news this Monday as the latest numbers show that dealership count and throughput are up, with stores averaging 511 new cars sold per year. Plus, we cover a quick turnaround for a vandalized Tesla charger and how United is upping its Wi-Fi game with Starlink internet.Show Notes with links:The U.S. new-car dealership count rose nearly 1% to 18,311 as of Jan. 1, 2025, up 171 from a year earlier, while the total franchise count fell 1.3% to 29,829, according to the latest Automotive News dealer census.Detroit 3 automakers shed dealerships, while import brands added stores with Ford Motor Co. leading the decline among the Detroit 3, losing 68 stores (a 2.2% drop). General Motors and Stellantis also reduced their dealership networks by 0.6%.Buick, Lincoln, and Jaguar continued trimming their franchise counts, with Buick experiencing the most significant reduction—down 135 to 927. Buick's franchise count has dropped by over half in the past two years due to dealer buyout offers.The number of exclusive dealerships across the industry as of Jan. 1 increased 3.5 percent to 13,226 from Jan. 1, 2024.The industry's average throughput (new-vehicle sales per franchise) increased by 5.8% to 511 vehicles in 2024, with the growth attributed to fewer franchises and an increase in U.S. light-vehicle sales to 15.35 million units, up from 14.9 million in 2023, according to Mary Raetz,director of the Automotive News Research & Data Center.Tesla swiftly repaired a vandalized Supercharger site in Massachusetts, bringing it back online in under 48 hours. The fire occurred overnight on March 2, 2025, causing wiring and Supercharger post damage, but the main cabinet remained intact.Tesla immediately communicated with customers on X (formerly Twitter), promising repairs within two days.Tesla is considering enhancing its Sentry Mode to deter future vandalism, potentially adding a honking feature.An arson investigation is underway with local police, though no suspects have been identified and the company is offering a $5,000 reward for information on the arsonists.United Airlines has installed its first Starlink system on a regional aircraft, bringing the airline closer to offering free, high-speed Wi-Fi across its fleet.The Starlink system offers free Wi-Fi to MileagePlus members, with speeds up to 250 Mbps—50 times faster than current in-flight internet.Installation is significantly quicker, taking just 8 hours compared to traditional Wi-Fi systems, which require over 10 days.The lighter Starlink equipment (85 pounds vs. up to 300 pounds) improves fuel efficiency and reduces aircraft downtime.United plans to install Starlink on over 40 planes per month, aiming to cover its entire regional fleet of 300 aircraft by the end of 2025."It's kind of enabling the living room in the sky experience," said Grant Milstead, UHosts: Paul J Daly and Kyle MountsierGet the Daily Push Back email at https://www.asotu.com/ JOIN the conversation on LinkedIn at: https://www.linkedin.com/company/asotu/ Read our most recent email at: https://www.asotu.com/media/push-back-email
Temporal Execution Framework: Unix AT Utility for AWS Resource OrchestrationCore MechanismsUnix at Utility ArchitectureKernel-level task scheduler implementing non-interactive execution semanticsPersistence layer: /var/spool/at/ with priority queue implementationDifferentiation from cron: single-execution vs. recurring execution patternsSyntax paradigm: echo 'command' | at HH:MMImplementation DomainsEFS Rate-Limit CircumventionAPI cooling period evasion methodology via scheduled executionUse case: Throughput mode transitions (bursting→elastic→provisioned)Constraints mitigation: Circumvention of AWS-imposed API rate-limitingImplementation syntax: echo 'aws efs update-file-system --file-system-id fs-ID --throughput-mode elastic' | at 19:06 UTCSpot Instance Lifecycle ManagementTermination handling: Pre-interrupt cleanup processes Resource reclamation: Scheduled snapshot/EBS preservation pre-reclamationCost optimization: Temporal spot requests during historical low-demand windowsUser data mechanism: Integration of termination scheduling at instance initializationCross-Service OrchestrationLambda-triggered operations: Scheduled resource modificationsEventBridge patterns: Timed event triggers for API invocationState Manager associations: Configuration enforcement with temporal boundariesPractical ApplicationsWorker Node IntegrationDeployment contexts: EC2/ECS instances for orchestration centralizationCascading operation scheduling throughout distributed ecosystemCommand simplicity: echo 'command' | at TIMEResource ReferenceAdditional educational resources: pragmatic.ai/labs or PIML.comCurriculum scope: REST, generative AI, cloud computing (equivalent to 3+ master's degrees)
We love to hear from our listeners. Send us a message. Andrey Doronichev, known to many simply as Dobry, is perhaps best known for taking YouTube mobile. You heard that right. If it weren't for him and the teams he led, YouTube might still be a desktop experience. He went on to lead product strategy at Google before launching the startup Optic in 2022. What's that got to do with biotech, you ask? Well, it's Optic where he feels his greatest contributions are to come, and his sights are set squarely on disrupting the way we discover therapeutic targets. On this episode of the Business of Biotech, Dobry, Life Science Leader Chief Editor Ben Comer, and I explore the intersection of AI and biotech, discuss Bioptic's beginnings and its approach to leveraging advanced screening technologies for drug discovery, and address Bioptic's biggest challenges -- data access and industry skepticism. Access this and hundreds of episodes of the Business of Biotech videocast under the Listen & Watch tab at bioprocessonline.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: matt.pillar@lifescienceconnect.comFind Matt Pillar on LinkedIn: https://www.linkedin.com/in/matthewpillar/
To learn more about Zack Estes and the work he is doing to help businesses, check out https://www.processarb.com/ Get free access to The Fire Time Magazine every month by going to https://www.itsfiretime.com/subscribe —— Order the latest issue of the printed Fire Time Journal: https://itsfiretime.com/journal. Support The Fire Time Podcast financially: https://www.patreon.com/itsfiretime. Become an Advertising Partner: https://www.itsfiretime.com/advertising
In this episode, Mike and Nick discuss three major trends they expect to shape crypto in 2025: the inevitable scaling challenges facing monolithic L1s like Solana and Ethereum, the expansion of rehypothecation across DeFi protocols and bridges, and massive growth in stablecoin adoption driven by regulatory tailwinds and institutional issuers. They explore technical constraints around L1 scaling, analyze the business dynamics pushing protocols toward rehypothecation, and examine why stablecoin market cap could exceed $450B. The conversation also covers complementary predictions around ZK proofs, TEEs, and the American crypto renaissance. Thanks for tuning in and happy holidays! - - Follow Nick: https://x.com/nickwh8te Follow Mike: https://x.com/MikeIppolito_ Follow Expansion: https://x.com/ExpansionPod_ Subscribe on YouTube: https://www.youtube.com/@expansionpod Subscribe on Apple: http://apple.co/4bGKYYM Subscribe on Spotify: http://spoti.fi/3Vaubq1 Get top market insights and the latest in crypto news. Subscribe to Blockworks Daily Newsletter: https://blockworks.co/newsletter/ -- Timestamps: (00:00) Introduction (01:48) Solana & Eth Scale Fails (07:25) American Crypto Renaissance (11:28) Institutions Launching Chains (19:58) Stablecoin Marketcap Exceeds $450B (24:30) 2025 is zk Year (29:24) TEE Growth (39:04) Fee Switches, Rehypotheticating Assets (45:23) Celestia 20mbps Throughput (50:26) AI & Crypto Bubble (1:00:23) New Media Models - - Disclaimer Expansion was kickstarted by a grant from the Celestia Foundation. Nothing said on Expansion is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only, and any views expressed by anyone on the show are solely our opinions, not financial advice. Rex, Jon, and our guests may hold positions in the companies, funds, or projects discussed.
Epicenter - Learn about Blockchain, Ethereum, Bitcoin and Distributed Technologies
One of the most limited blockchain resources is blockspace. From Bitcoin's Blocksize Wars to Ethereum's scaling roadmap, a common denominator seems to have emerged in the form of rollups. Advancements in zero knowledge proofs have enabled trustless bridges, which are a cornerstone to onboarding liquidity to any blockchain. Furthermore, Celestia's modular approach to blockchain architecture and their recent commitment to gigabyte blocks of data availability marked the beginning of commoditization for rollups. Abundance is the first rollup-as-a-service platform that is able to scale to 1 gigagas/second throughput, finally bringing off-chain applications, on-chain.Topics covered in this episode:Gelato's pivot to rollup-as-a-service platformSovereign rollupsEnshrined bridges and settlement proofsAbundance and 1 Gigagas/second rollupsModularitySecurity assumptionsSequencer (de)centralisationSocial consensusCelestia's DA layer bandwidthEthereum native rollupsDecentralisation and censorship-resistanceEpisode links:Hilmar Orth on XGelato Network on XAbundance on XSponsors:Gnosis: Gnosis builds decentralized infrastructure for the Ethereum ecosystem, since 2015. This year marks the launch of Gnosis Pay— the world's first Decentralized Payment Network. Get started today at - gnosis.ioChorus1: Chorus1 is one of the largest node operators worldwide, supporting more than 100,000 delegators, across 45 networks. The recently launched OPUS allows staking up to 8,000 ETH in a single transaction. Enjoy the highest yields and institutional grade security at - chorus.oneThis episode is hosted by Friederike Ernst.
Send us a textThe intersection of artificial intelligence and biology presents immense opportunities for transforming bioprocess development. As the biotech industry continues to evolve, data-driven innovations are critical to optimizing biologics manufacturing. High-quality datasets stand at the forefront of this transformation, empowering researchers to make informed predictions and advance therapeutic discoveries. As AI tools become more commoditized, the focus shifts toward generating robust and extensive datasets to maximize the potential of machine learning in biological applications.Miniaturization has emerged as a vital enabler in this data-driven approach. Miniaturized systems allow researchers to conduct thousands of tests in an area no larger than the palm of your hand. This drastic reduction in material and resource requirements makes high-throughput screening feasible, economical, and scalable.Traditional liquid handling robots can manage thousands of tests per day, but each test requires considerable amounts of material, usually leading to high costs. Conventional systems can cost anywhere from $10 to $100 to get a single genotype sequence from discovery to sequencing. Miniaturization can bring these costs down to mere pennies per data point, making it possible to scale the dataset size exponentially.Key takeaways from our discussion:The future of AI in biology relies heavily on large, well-annotated datasets. Without them, the full potential of AI remains untapped. High-quality data enables more accurate predictions of protein structures and functions.Success in bioprocess development often involves collaboration with partners across the value chain. By working together, companies can leverage their unique strengths and expertise to overcome barriers and innovate more efficiently.Advancements in miniaturization technology allow for high throughput screening at reduced costs. This shift makes it viable to generate large datasets, speeding up the pace of discovery and making AI-driven predictions more accessible.This episode is essential for anyone eager to explore the transformative fusion of AI and biotechnology. Jeremy Agresti highlights the future of bioprocessing at the intersection of high-throughput screening, miniaturization, and AI, revealing how these innovations are solving complex challenges, driving breakthroughs, and shaping the future of science and medicine.Connect with Jeremy Agresti:LinkedIn: www.linkedin.com/in/jeremy-agresti-88546850/Triplebar: www.triplebar.comNext Steps:Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessmentDevelop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Learn more at https://bruehlmann-consulting.com
Send us a textBioprocess development is transforming the biotech industry, driving innovations in life-changing therapies. Success hinges on simplifying complex mechanisms and adopting advanced technologies. By integrating high-throughput screening and artificial intelligence, we can streamline workflows, reduce trial-and-error, and speed up biologics development. Embracing cutting-edge tools empowers scientists to maximize biology's potential, delivering efficient and impactful biotech solutions.In this episode of The Smart Biotech Scientist Podcast, host David Brühlmann explores these transformative methodologies with Jeremy Agresti, CTO and founder of Triplebar.Jeremy highlights the future of bioprocessing at the intersection of high-throughput screening, miniaturization, and AI. With tools that enhance predictability, scalability, and efficiency, Triplebar is set to transform biotechnology. By reimagining traditional methods, improving inputs, and leveraging modern technology, companies like Triplebar are driving a new era in bioprocessing, offering innovative solutions to complex biological challenges.Key Takeaways:Jeremy challenges the traditional view of scale-up issues, emphasizing that many problems can be solved at a smaller scale with better engineered strains and cell lines.By creating tiny bioreactors of droplets, Triplebar is able to perform high throughput screening, testing millions of mutations quickly and efficiently, and providing robust solutions for complex biological functions.The integration of massive data sets with AI allows for improved enzyme and protein design, unlocking the potential to innovate even when foundational understanding is limited.Ready to dive deeper? Join the journey of transforming bioprocess development with smart insights and pioneering spirit. Catch up with Jeremy's full story via the latest episode of the Smart Biotech Scientist podcast.Connect with Jeremy Agresti:LinkedIn: www.linkedin.com/in/jeremy-agresti-88546850/Triplebar: www.triplebar.comNext Steps:Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessmentDevelop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Learn more at https://bruehlmann-consulting.com
José M. García, CEO and Director of Silver X Mining (TSX.V:AGX – OTCQB:AGXPF), joins me to review the Q3 2024 financials and operations from the Tangana Mine at the Nueva Recuperada Project, located in central Peru. We also look ahead to Q4 operations thus far, and the plans to expand the mill capacity to grow production, in tandem with exploration success raising the grade profile and factoring into an updated Resource Estimate in Q1. We start off by having José outline some of the key takeaways from the Third Quarter 2024 financials and operations announced to the market on November 28th. He points out the mine performed well, despite having challenges and interrupting some production in September, and that the All-In Sustaining Costs were affected by capital invested into Tangana in Q3. Revenues of $5.0 million (3Q24) vs. $2.1 million (3Q23), an increase of $2.9 million. Significant EBITDA improvement: Adjusted EBITDA of negative $0.1M (3Q24) vs. Adjusted EBITDA of negative $1.0M (3Q23). Cash costs of $21.5 per AgEq ounce produced and AISC of $26.2 per AgEq ounce produced, reflective of the sustaining capital expenditure invested in the development of the Tangana mining unit ($1.0 million adding $3.9 per AgEq ounce produced to the AISC). Cash cost per tonne was $100 in 3Q24 compared to $148 per tonne in 3Q23, a reduction of 32.3%. Next we get into a discussion on the current plant capacity of 720 tpd, but that there is an initiative in place to get access to some healthy corporate debt to expand the plant and also build a second plant, which would allow for a large increase in throughput, which would bring costs down with better efficiencies. José also points to the upcoming update to the Resource Estimate due out in Q1, where it will show increasing the deposit size and grade. We also discuss all the exploration upside the Company has across its district scale land package, not just at the Tangana Mining Unit, but also at both the Plata Mining Unit and Red Silver Mining Unit. If you have any questions for José regarding Silver X Mining, then please email me at Shad@kereport.com, and we'll get those addressed by management or covered in future interviews. In full disclosure, Shad is a shareholder of Silver X Mining at the time of this recording. Click here to follow the latest news from Silver X Mining
My podcast guest this week is Andy Nightingale, Vice President Product Management & Marketing at Arteris. Andy and I chat about the key challenge faced by SoC designers when building NoC interconnects for AI based designs, the details of NoC interconnect IP soft tiling and some real world examples of AI based designs that benefit from NoC IP soft tiling. Also this week, I check out how odor detection by the silkworm moth could improve localization technologies in robotics.
In Part 2 of this series, Miyanovich weaves the concept of The Anthropologic Requirement into his previous discussion and covers: the colorless, genderless, universal reality that lies beneath the resource reality, the toxicity of left-wing irrationality, and the coming backlash from The Waking Giant of The Center.
Velocity & Throughput Are Full of Crap - I Think NOT... Join V. Lee Henson as we review an article that was written to rebuff the way that I treat story points and velocity without them making an effort to understand why I have success with this approach. How to connect with AgileDad: - [website] https://www.agiledad.com/ - [instagram] https://www.instagram.com/agile_coach/ - [facebook] https://www.facebook.com/RealAgileDad/ - [Linkedin] https://www.linkedin.com/in/leehenson/
Liam Eagen (Alpen Labs), Robin Linus (Zero Sync, BitVM) & Jonas Nick (Blockstream, Taproot) talk about their groundbreaking research paper about Shielded Client-Side Validation – a new way to bring privacy & scalability to Bitcoin. –––––––––––––––––––––––––– Time stamps: Introduction (00:00:51) What is Client-Side Validation? (00:02:09) Trade-offs in Client-Side Validation (00:04:20) Comparison with Existing Protocols (00:05:18) On-chain Throughput and Privacy (00:09:21) Connecting Bitcoin and Shielded CSV (00:09:55) User Interaction with the Protocol (00:11:07) Challenges with the Lightning Network (00:12:22) Atomic Swaps and Compatibility (00:14:56) Shielded CSV vs Monero & Zcash (00:16:12) Discussion on STARKs (00:19:28) OP_CAT and Covenants (00:21:46) OP_CAT and Functional Encryption (00:24:03) Exploration of BitcoinOS (00:25:21) Potential of BitVM (00:26:11) Bitcoin as a Currency (00:28:21) Funding for CSV Projects (00:30:40) Taint Concept in Shielded Transactions (00:31:14) Adoption and Privacy Protocols (00:34:08) Transaction Fees in Shielded Transactions (00:35:08) Throughput and Base Layer Efficiency (00:36:04) Node Behavior During Transactions (00:38:12) Comparison with MimbleWimble (00:39:41) CryptoSteel's New Device (00:40:29) Drivechains (00:41:04) Discussion about crypto steel backups and a sponsor, Layer Two Labs, promoting drive chains. Concerns Over Soft Forks (00:43:51) Rough Consensus Definition (00:45:04) Challenges of Soft Fork Implementation (00:46:15) Balancing Stability and Innovation (00:47:29) Miner Incentives and Fee Structures (00:48:38) Future of Post-Quantum Proposals (00:49:44) Increasing Block Size for CSV (00:50:00) Ideal Block Size Debate (00:53:08) Quantum Computing Threat (00:59:02) Potential Consequences of Quantum Attacks (01:00:24) Post-Quantum Solutions (01:02:23) Quantum Computing Timeline (01:02:50) Complexity of Quantum Computers (01:03:31) Quantum Records and Limitations (01:05:44) Chat Question on Shielding Protocol (01:06:12) Hodling.ch (01:06:45) Self-Custody Security (01:09:15) Threat Models in Security (01:09:58) Hardware Wallet Cautionary Tale (01:10:33) Conference Discussions (01:12:05) Shielded CSV Funding and Development Timeline (01:13:58) Prototype Development Outlook (01:15:29) Concerns Over Adoption (01:17:31) Scalability vs. Privacy Debate (01:19:34) Tether on Shielded CSV? (01:22:04) Revenue Models Discussion (01:22:22) Transaction Fees and Profitability (01:23:25) Publisher Fees in CSV Protocol (01:24:16) Competition and Business Models (01:25:40) Soft Fork Proposals for Improvement (01:26:07) Script Restoration and Arithmetic Improvements (01:27:30) Future of Shielded Client-Side Validation (01:37:23) Keeping Up with Developments (01:38:44) Self-Promotion and Team Dynamics (01:41:05) Proof of Stake? (01:42:51) Rare Pepes in Shielded CSV (01:43:56) Acknowledgment of Guests (01:46:18) Call to Action: Shield Emoji (01:47:57) Importance of Learning Bitcoin (01:48:07) Resources for Learning Bitcoin (01:48:31) Commentary on Peter Wuille (01:49:26) Block Size Debate (01:50:02) Optimizing Bitcoin for Global Use (01:51:05)
Avery Ching is the CTO of Aptos Labs and the one of the Co-Founders of Aptos. Avery's Twitter: https://x.com/AveryChing Aptos's Twitter: https://x.com/Aptos Aptos's Website: https://aptosfoundation.org/ Logan Jastremski's Twitter: @LoganJastremski Frictionless's Twitter: @_Frictionless_ Frictionless's Website: https://frictionless.fund/
Ever wondered when it's okay to break the rules and step outside your established processes? In this episode, Marc sits down with Jordan Muela of LeadSimple to explore the delicate balance between processes and judgment in property management. Discover Jordan's entrepreneurial journey, the importance of cycles and fascination in business, and his expert advice on starting and scaling a property management company. Learn how to identify the right location, establish key principles for success, and align incentives to create a motivated and engaged team. Gain valuable insights from a seasoned entrepreneur on navigating the complexities of property management, building a successful company, and fostering a thriving team. Get your free LeadSimple demo here. Click here to reserve your spot at the LeadSimple University December event. Click this link to learn more about Rentvine. To find out more about Marc's coaching services click here. Follow this link to spend 2 days with Marc and learn how to run a property management business Join Marc's new property management Facebook group This podcast is produced by Two Brothers Creative 2024.
When people reject the concept of degrowth are they suggesting society continue to allow capital to ravage the earth? Are they saying the countries of the global North should continue exploiting and extracting from the global South? Are they pushing for more growth? Steve's guest, Erin Remblance is an Australian researcher and activist who was spurred into action six years ago when the IPCC released their special report on global warming of 1.5°C. Since then, Erin has been creating courses, events, and materials that address the crises and work toward solutions. Erin and Steve discuss degrowth, a planned reduction in energy and material throughput to maintain ecological balance. (Throughput, for those unfamiliar with the term, is defined as “the amount of material or items passing through a system or process.”) The episode goes into the systemic issues of capitalism, which increasingly commodifies all areas of our lives in its relentless pursuit of growth. “The gross national product does not allow for the health of our children, the quality of their education or the joy of their play. It does not include the beauty of our poetry or the strength of our marriages, the intelligence of our public debate or the integrity of our public officials. It measures neither our wit nor our courage, neither our wisdom nor our learning, neither our compassion nor our devotion to our country. It measures everything in short, except that which makes life worthwhile.” Robert F. Kennedy, 1968, included in Erin's slide presentation, An Introduction to Degrowth Follow Erin Remblance and find her work on LinkedIn, Substack, and Twitter: https://www.linkedin.com/in/erin-remblance/ https://erinremblance.substack.com/ https://twitter.com/remblance_erin https://the-healthy-habits-accelerator.circle.so/c/start-here/the-rules
Increasing Electronic Design Automation (EDA) performance and throughput is critical to Intel's silicon Design engineers. Silicon chip Design engineers at...[…]
Dive into the transformative world of bead-based assays with Sebastian Giehring, CEO and founder of PAIA Biotech, where high-throughput screening meets cutting-edge biotechnological advancements.Join us as we chat with Sebastian, a seasoned scientist and entrepreneur who has revolutionized the workflow of high-throughput screening of titer, glycosylation, and aggregation with innovative bead-based assays.Key Takeaways:Streamlined Workflow: Learn how a simplified sample prep can enhance efficiency and accuracy in glycosylation and aggregation screenings.Optimized Experiment Design: Discover the critical do's and don'ts in designing robust experiments that yield meaningful results.Future of Screening: Explore how AI and machine learning are set to revolutionize the biotechnological landscape, driving better drug development and process optimization.Tune in to uncover how these insights can transform your lab's capabilities and drive groundbreaking discoveries!Connect with Sebastian Giehring:LinkedIn: https://www.linkedin.com/in/sebastian-giehring-6ba1992PAIA Biotech: https://www.paiabio.comNext Steps:Book a free assessment to help you get started with the design of your next experiment at https://bruehlmann-consulting.comDevelop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at hello@bruehlmann-consulting.com
Ready to revolutionize your lab work? Join us as we dive deep into bead-based assays with Sebastian Giehring, CEO and founder of PAIA Biotech.Discover how these tiny beads are making a massive impact on biotech research and development — for titer, glycan, and aggreation screening — and how this developability screening platform can enhance your antibody discovery, antibody engineering and lead optimization.In this episode, you'll learn:Speed and Simplicity: How bead-based assays offer unmatched throughput and ease of use, allowing you to analyze hundreds of samples in just a few steps.Versatile Applications: The diverse applications of bead-based assays in cell development, bioprocessing, and antibody discovery, helping streamline workflows and enhance innovation.Early Screening Advantages: The benefits of bead-based assays in early-stage process development, enabling quick decision-making with less detailed but rapid results.Tune in to uncover how these assays can transform your biotech research and push the boundaries of what's possible!Connect with Sebastian Giehring:LinkedIn: https://www.linkedin.com/in/sebastian-giehring-6ba1992PAIA Biotech: https://www.paiabio.comNext Steps:Book a free assessment to help you get started with the design of your next experiment at https://bruehlmann-consulting.comDevelop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at hello@bruehlmann-consulting.com
Avipaul Bhandari: Measuring Scrum Master Impact Beyond the Lean and Agile Metrics Read the full Show Notes and search through the world's largest audio library on Scrum directly on the Scrum Master Toolbox Podcast website: http://bit.ly/SMTP_ShowNotes. In this episode, Avipaul explores the the many sides of success for Scrum Masters. Beyond metrics like cycle time and throughput, he emphasizes the importance of team smiles and voluntary contributions. Featured Retrospective Format for the Week: The Timeline Retrospective In this segment, Avipaul introduces the Timeline Retrospective, ideal for reflecting on the end of a phase. This format connects team members' emotions to their journey, fostering a deeper understanding and appreciation of their shared experiences. The timeline retrospective can highlight the human sides projects, and enhance the team's ability to reflect and learn. [IMAGE HERE] Retrospectives, planning sessions, vision workshops, we are continuously helping teams learn about how to collaborate in practice! In this Actionable Agile Tools book, Jeff Campbell shares some of the tools he's learned over a decade of coaching Agile Teams. The pragmatic coaching book you need, right now! Buy Actionable Agile Tools on Amazon, or directly from the author, and supercharge your facilitation toolbox! About Avipaul Bhandari Avipaul is a seasoned Agile Coach with extensive experience helping teams and organizations implement Agile practices effectively. His expertise spans various domains, and he is passionate about fostering collaboration and continuous improvement. You can link with Avipaul Bhandari on LinkedIn and connect with Avipaul Bhandari on Twitter.
There have been data revolutions in most areas of human activity, and biological research is no exception. The rapidly shrinking cost of collecting data like DNA sequences means that there has been an exponential growth in the amount of data that bio researchers have at their disposal. Yet, most biologists still operate on top of general purpose cloud compute platforms, which don't offer a native environment for them to engage in research at the cutting edge of the field. On the Riskgaming podcast today, Lux's Tess van Stekelenburg interviews Alfredo Andere and Kenny Workman, the co-founders of LatchBio who are on a quest to rapidly accelerate the progress of biology's tooling. The big challenge — even for big pharma — is a lack of access to top-flight AI/ML developers in the ferocious talent wars they face against even bigger Big Tech companies. As Workman says, “They just don't have world's best machine learning talent … And then they're working with usually 5- to 10-year-old machine learning technology, except for a small handful of outliers.” LatchBio and other startups are pioneering new ways of delivering those tools to biologists, today. In this episode, the trio discuss the changing data economy of biological research, the lack of infrastructure for conducting laboratory and clinical work, why AstraZeneca has improved its pharma output over the past decade, what the ground truth is around AI and bio, the flaws of open-source software, and finally, how academia and commercial research will fit together in the future.
Welcome to Boosting Your Financial IQ, I'm Steve Coughran, your host. Today, we're exploring one of the most crucial yet often overlooked metrics in business: throughput. Throughput measures the rate at which a system can produce results, whether it's revenue per hour, gross margin per hour, or any other financial metric as a function of time. Understanding and optimizing throughput is essential for maximizing efficiency and profitability in your business operations. By focusing on improving throughput, businesses can identify bottlenecks, streamline processes, and ultimately increase productivity. Join me as we dive into the intricacies of throughput and discover how harnessing this metric can drive significant improvements in your bottom line. Tune in and elevate your financial IQ to new heights.Access the free course "The Million Dollar Blueprint" here > Email Steve your thoughts at steve@byfiq.comHelpful links:Join the Strategic Financial Mastery programJoin Our Free CommunityTrain your team with an on-site workshopDisclaimer:BYFIQ, LLC is a wholly owned entity of Coltivar Group, LLC. The views expressed here are those of the individual Coltivar Group, LLC (“Coltivar”) personnel quoted and are not the views of Coltivar or its affiliates. Certain information contained in here has been obtained from third-party sources. While taken from sources believed to be reliable, Coltivar has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. The Company is not registered or licensed by any governing body in any jurisdiction to give investing advice or provide investment recommendations. The Company is not affiliated with, nor does it receive compensation from, any specific security. Please see https://www.byfiq.com/terms-and-privacy-policy for additional important information.Support the Show.
In this episode of the Launch Digital Dentistry Podcast, I chatted with Dr. Tarun Agarwal who reflects on the dramatic shift from traditional dental practices to the integration of cutting-edge technologies like AI-driven press technology. They discuss the critical role of technology in enhancing accessibility and efficiency in dental care, the importance of adapting to new tools and overcoming the challenges of information overload.Dr. Tarun Agarwal, also known as 'T-Bone', is a thought leader and innovator in dental education. As the founder and CEO of Raleigh Dental Arts and 3D Dentists, Dr. Agarwal has trained over 10,000 dentists on managing and thriving in a busy dental practice environment. His extensive experience and commitment to education have made him a pivotal figure in transforming dental practices through technology and continuous learning.What we talked about:[00:00] Intro[01:54] Insights and Inaction in Dentistry[04:18] Affordable Innovations Making Dentistry Accessible[06:39] From 2D Imaging to AI-Driven Tech[08:45] Input, Throughput, Output Explained[12:33] Tech Trivia and Trends[15:01] The Generational Tech DivideConnect with Dr. Tarun Agarwal here:https://www.3d-dentists.com/https://www.instagram.com/tbonespeaks/https://3d-dentists.com/podcast/Connect with Dr. Shea Tolbert here:https://www.fdhonline.com/https://www.linkedin.com/in/shea-tolbert-dmd-fagd-23584a28/https://www.instagram.com/launchdigitaldentistry/https://www.instagram.com/shea.tolbert/
Frankly Speaking | Real World Topics With Real World Experts
Join Technical Director, Jose Ramirez, as he discusses overcoming the challenge of balancing throughput goals with pellet quality.
Metaphors like funnels and flywheels fall short in capturing the true complexity of business systems. We should pay attention to and understand systems thinking, taking a holistic view to understand bottlenecks and optimize for throughput rather than efficiency.If you like the show, please subscribe and rate the show!For updates on new episodes follow us on:LinkedIn: Lift Enablement, Doug Davidoff, Jess CardenasYou can also watch the video version of the show on our page. Thanks for listening and remember to just say no to shitty RevOps!
Frankly Speaking | Real World Topics With Real World Experts
Balancing throughput with high-quality pellets is the ultimate feed milling goal. Listen in with Jose Ramirez to find out how to achieve it.
In this BONUS episode, we delve into the merging of Scrum and Kanban with Todd Little, Chairman at Kanban University, and Joey Spooner, Vice President of Product Management at Kanban University. Join us as we uncover the journey and strategies behind integrating Scrum and Kanban to replace project management and enhance team productivity. The Genesis of Agile and Kanban Integration "Finding the right balance between Scrum and Kanban came from a need to handle uncertainty in tech projects better," explains Todd. Both leaders discuss their initial encounters with agile methodologies and how challenges in their projects led them to innovate and blend Scrum with Kanban to improve flexibility and responsiveness. Understanding Scrum and Kanban "There's a historical divide between the Scrum and Kanban communities, but bridging them can significantly enhance how teams operate." Notes Joey. They break down the fundamental aspects of Scrum and Kanban, explaining how each contributes uniquely to managing projects and how combining them can mitigate the limitations of using one over the other. Real-World Benefits of a Hybrid Approach Todd shares a case study from Vanguard, highlighting their "Scrum stall" and how integrating Kanban principles like mapping work flows and setting WIP limits dramatically improved cycle times and overall efficiency. Joey adds, "Visualizing work and adjusting processes to reduce bottlenecks, especially in QA, transformed our team dynamics and output." Challenges and Insights in Combining Methodologies "Start where you are, and evolve incrementally," advises Todd Todd and Joey emphasize the importance of recognizing current practices and gradually introducing Kanban elements to enhance Scrum frameworks. Joey reflects on early challenges in adoption, suggesting a cautious approach to avoid overwhelming teams and to foster more sustainable improvements. Navigating Change and Resistance The discussion touches on managing resistance to change. Todd and Joey highlight strategies like using historical data for forecasting and focusing on evolutionary change to gain buy-in from stakeholders and team members, ensuring a smoother integration of practices. What Does Agile Look Like, When We Push it to 11? Looking ahead, Todd envisions a focus on refining product discovery processes to make workplaces more dynamic and fulfilling. Both speakers emphasize the importance of continuous improvement and pushing the boundaries of current agile practices to maximize their impact. Learn More and Connect To explore more about integrating Scrum with Kanban and to connect with Todd and Joey, visit the Kanban University website or find them on LinkedIn (see links below). Also, don't miss the upcoming Product Owner Summit for more insights from industry leaders. About Todd Little Todd Little is the Chairman of Kanban University, a seasoned executive, and a pioneer in lean and agile methodologies. His extensive experience in leading technology developments and his contributions as an author and speaker have positioned him as a key figure in global project management circles. You can link with Todd Little on LinkedIn and connect with Todd Little on Twitter. About Joey Spooner Joey Spooner is the Vice President of Product Management at Kanban University, with a rich background in managing complex projects across various industries. He holds a degree from the University of Florida and is known for his innovative approaches to community development and product management. You can link with Joey Spooner on LinkedIn.
“Throughput is really exciting when you connect those three areas, so what does that ecosystem look like?We make sure we are branching out and seeking underrepresented talent and also talent who have amazing experience. We do that in our acquisition process”, says Christina Parr as she discusses her role of combining talent acquisition, learning & development and organizational development. “As folks flow into the organization, we're developing them to grow within the organization regardless of where they happen to come in at from a skill perspective.And then as we look at the organization and how it's developing, we have a lot of touch points, that we ask employees from a pulse perspective.”On the podcast this week, Argo Group's Head of Global Talent Acquisition, L&D and OD talks about her career journey from high-tech and oil & gas in to insurance. “With quite a bit of reluctance I came to insurance. And until I really understood what was happening in the future of insurance, Insurtech, fintech, wasn't all that excited. I love it, it's addictive.”Christina talks about the balance between attracting under-represented talent and through referrals. “I understand now why we tend to talk to a lot of folks who have vast experience in the market. But we also have to keep ourselves in check with that bias because if we get too heavy on referrals, we don't dig deep for underrepresented talent. It's easy to fall into just kind of staying with the folks that you've known for so long.”She shares how Argo Group are breaking down inter-departmental siloes, traditions and using data to transform employee engagement. “We want to try things in different ways. By doing that, I think it makes us far more effective. We partner with a third party who brings us about 10 million data points from around the globe. And we use those benchmarks to compare our employee engagement results.For the last five surveys, we've been going up and up and up, which is quite remarkable as we've been going through strategic alternatives.”Christina highlights the impact of the Brookfield Asset Management acquisition. “Most people in the organization were eagerly anticipating this transformation.Once the buy was completed, our executive team not only presented the direction, but more importantly, listened to people.‘What's going well, what's not going well, what do we need to change?'I very much appreciated that perspective. Values are being revisited to make sure everyone understands that integrity is first.We are transitioning the business to three towers. Casualty, Financial Lines and Surety, and Specialty Lines. They are in many different business areas and we get to be the arm of Specialty that they otherwise did not have.”In terms of the impact on the day-to-day, Christina says: “We have a focus on the right people in the right spots with the right skills. You've got to get the big people on the bus before you start going anywhere.We've had some shifts in how our is talent positioned. One out of 10 are getting a promotion in some way, shape or form.We've also been working with our socio-economic employee resource group to make sure that we give plenty of people, a chance to succeed who may not be traditional in their background. How we then train them, give them the right skills and then we promote them, thereby making the organizational more healthy and sustainable.” Christina emphasizes how the 8 employee resource groups are working to reduce barriers to entry and expand the prospective talent pool. “About a third of our roles do not require a degree now. That's a big change. In most companies, you've got the requirement for a degree, specialty certifications, Master's degrees. You can see why unfortunately, we're not getting underrepresented talent. We've worked very...
AABP Executive Director Dr. Fred Gingrich is joined by Dr. Juan Rodrigo Pedraza, AABP member and Zoetis Technical Services Veterinarian. This episode is brought to you by the AABP Milk Quality and Udder Health Committee. Pedraza starts by explaining what is parlor efficiency and throughput and why it is important for dairy farms. He cautions that recommendations to improve parlor efficiency should not sacrifice quality milk production and veterinarians can consult dairy clients on steps to improve both. There are many factors that we should consider when evaluating parlor efficiency. These include loading speed, pulsation rate and ratio, teat end vacuum, mouth piece vacuum and automatic take off settings. Pedraza explains that although specialized testing equipment is needed for some of these assessments, observing parlor procedures, timing and milk flow at the end of milking can be a first step in assisting producers with parlor efficiency. Pedraza also points out how veterinarians can work with employees in the milking parlor to improve procedures, emphasizing the importance of explaining why we are implementing procedures and delivering messaging appropriately. Veterinarians can play a valuable role in parlor procedures and fine-tuning milking equipment to improve parlor efficiency and milk quality. Find AABP resources from the Milk Quality and Udder Health committee resources page. A previous podcast on the importance of pre-milking stimulation that is reference in this podcast can be found here. Erskine RJ, Norby B, Neuder LM, Thomson RS. Decreased milk yield is associated with delayed milk ejection. J Dairy Sci. 2019 Jul;102(7):6477-6484. doi: 10.3168/jds.2018-16219. Epub 2019 Apr 25. PMID: 31030923.
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The Automotive Troublemaker w/ Paul J Daly and Kyle Mountsier
Welcome to Tuesday as we talk about franchise dealership count going down while throughput goes up on the other side of the seesaw. We also talk about Dealer complaints about the use of AI in credit leading to misquotes on payments, as well as a follow up on the dealer-purchased Cybertruck from last week.In 2023, the U.S. saw a slight decrease in new-car dealerships but a notable rise in sales per franchise underscoring the balance between efficiency and high demand. Note: The count excludes excludes BrightDrop, Fisker, Karma, Lucid, Rivian, Tesla and VinFast The U.S. new-car dealership count dropped to 18,133 in 2023, while average sales per franchise surged 14% to 483 vehicles, up from 425General Motors and Ford led the charge in reducing franchise counts, contributing to an overall 3.6% decrease in franchises.Notably, Buick dealerships nearly halved from 1958 to 1052, but doubled their throughput to 111 Lincoln cut 100 of its US franchises bringing the total count to 535 and has plans to cut 100 more this yearHyundai and Genesis are expanding their standalone presence, signaling a shift towards more brand-exclusive dealerships."We are well on our way to 75 percent-plus of our network upgrading their facilities by 2025," says Hyundai spokesperson, highlighting a focus on modernization and brand distinction.A staggering 90% of dealers and lenders report frustrations with AI in digital lending solutions, claiming it often results in inaccurate online payment quotes, a poll by eLEND Solutions reveals.The majority feel that AI's approach to evaluating consumer creditworthiness doesn't align with the reality of customer negotiations, leading to mismatched payment terms."Lenders aren't even pricing to those [rate sheet] tiers any longer," eLEND CEO Pete MacInnis told Automotive News. "Some are, but most of your major ones have this dynamic pricing model" tied to the unique customer and their vehicle choice.Despite AI's sophistication, 76% of initial digital retail quotes reportedly fail to match final lender decisions, highlighting a disconnect between technology and practical application.The Porsche dealer that turned heads last week by acquiring a Cybertruck for $244,000, at a Manheim auction now has it listed for $289,999Porsche South Orlando acquires a Cybertruck for $244,000 from seller “givemethevin” and, now has it listed for $289,999, defying Tesla's resale restrictions which threaten a $50,000 penalty for early resales, the truck has traveled through multiple owners, each turning a profit.The Cybertruck, with under 100 miles on the odometer"Tesla's threat...may have actually helped to inflate the price of the trucks," suggests John Clay Wolfe, CEO of givemethevin.com, pointing to a temporary market anomaly.Hosts: Paul J Daly and Kyle MountsierGet the Daily Push Back email at https://www.asotu.com/ JOIN the conversation on LinkedIn at: https://www.linkedin.com/company/asotu/ Read our most recent email at: https://www.asotu.com/media/push-back-email ASOTU Instagram: https://www.instagram.com/automotivestateoftheunion
Anatoly needs no introduction. He is responsible for the creation of Solana and the emergence of high-throughput, next-gen blockchains. We had the privilege of covering a very wide variety of topics with 'Toly thoughout this interview. We start with ‘Toly's childhood, background, and the origins of Solana. We then move into some of Solana's core principles and how they differ from Ethereum. This serves as a natural segue into Solana's upcoming technical upgrades, changes to its fee model, learnings from other ecosystems, and what happens after Firedancer. ‘Toly also address some of Solana's key criticisms and open questions head-on, such as decentralization initiatives and moneyness properties. This must-listen episode is the most comprehensive and up-to-date overview of the Solana blockchain from the man who built this ~$60B (and counting) from the ground-up. - - Time Stamps (0:00) - How Toly's childhood influenced him (3:24) - Toly's route into crypto (6:15) - The origins of Solana (11:17) - Why POH's core value prop is different than originally envisioned (14:15) - Has Solana created a level playing field for trading yet? (21:24) - Where will finance ultimately exist? (25:10) - Interplay between Sol and Eth ecosystems (27:29) - Solana's modularity (31:27) - Upgrading the fee markets (39:44) - How will Solana handle MEV over a bull market (43:46) - Is Solana ready for mass adoption? (46:27) - Next technical hurdle post Firedancer (48:52) - Integreting DePIN friendly features into the Saga 2 (51:30) - Is Crypto x AI overhyped? (58:16) - Teachings from other L1 ecosystems (1:00:42) - No 10x improvements possible over Solana's design? (1:02:02) - implications of a multi-validator client future (1:07:03) - Solana becoming an Eth L2 shared sequencer? (1:08:08) - Solana's moneyness properties (1:10:35) - When will Solana be decentralised enough? (1:15:21) - The end of the good old days? (1:16:25) - Which projects excite Toly (1:19:46) - How Toly touches grass (1:21:05) - Toly's advice for this cycle - - Podcast Resources Follow Sal: https://twitter.com/salxyz Follow Dave: https://twitter.com/SolBeachBum Follow Unlayered: https://twitter.com/UnlayeredPod Subscribe on Spotify, Apple, or Google: https://unlayered.io/ Subscribe on YouTube: https://www.youtube.com/@UnlayeredPod - - Episode Resources Follow Anatoly : https://Twitter.com/AEYakovenko
In this podcast, we dive deep into the world of Bitcoin scalability solutions with Orkun Kilic, the co-founder and CEO of Chainway Labs, the company behind Citrea - Bitcoin's first zero-knowledge (ZK) rollup. Orkun provides a detailed background on the journey that led to the creation of Citrea, explaining how recent upgrades to Bitcoin's protocol like SegWit, Taproot, and the Ordinals protocol paved the way for new possibilities by enabling arbitrary data storage on the blockchain. This opened up a design space for building scalable layer 2 solutions on top of Bitcoin. The core innovation behind Citrea is the use of ZK proofs and the groundbreaking BitVM (Bitcoin Virtual Machine) primitive to create a trust-minimized bridge between Bitcoin's base layer and the Citrea rollup. Orkun goes into the technical depths of how BitVM works, allowing off-chain virtual machine computations to be proven valid on Bitcoin's blockchain through an interactive fraud proof verification game. Citrea's EVM compatibility and the plan to attract developers by tapping into Bitcoin's trillion-dollar liquidity are covered in-depth. Orkun envisions Citrea becoming a "programmable liquidity layer" enabling DeFi protocols, stablecoins, and innovative decentralized applications while inheriting Bitcoin's security and decentralization. With its comprehensive technical insights and forward-looking perspectives, this episode is for anyone interested in the future of programmable money on Bitcoin. Key Links Citrea: https://citrea.xyz Socials Orkun's Twitter Can's Twitter Tommy's Twitter Follow Delphi Digital Website: https://members.delphidigital.io/home Twitter: https://twitter.com/Delphi_Digital Youtube: https://www.youtube.com/@Delphi_Digital Disclosures Disclosures: This podcast is strictly informational and educational and is not investment advice or a solicitation to buy or sell any tokens or securities or to make any financial decisions. Do not trade or invest in any project, tokens, or securities based upon this podcast episode. The host and members at Delphi Ventures may personally own tokens or art that are mentioned on the podcast. Our current show features paid sponsorships which may be featured at the start, middle, and/or the end of the episode. These sponsorships are for informational purposes only and are not a solicitation to use any product, service or token. Delphi's transparency page can be viewed here. Keywords Bitcoin, Citrea, ZK Rollup, Scalability, BitVM, Optimistic Bridge, BTC, Programmable Liquidity, Developer Ecosystem, DeFi, Stablecoins, Decentralized Applications, Turing-Complete, Trust-Minimized, Ordinals, Taproot, SegWit, Data Compression, State Diffs, Throughput, Adoption, Ethereum, Layer 2 (L2), Chainway, --- Send in a voice message: https://podcasters.spotify.com/pod/show/the-delphi-podcast/message
Dominic Williams is the Chief Scientist of the DFINITY project Step into the era of blockchain as a limitless smart contract cloud that hosts everything on-chain: data, content, computations, and user experiences. Forget legacy IT and build tamperproof and unstoppable Web3 social media, gaming, virtual reality, decentralized finance, and enterprise infrastructure. Join the movement and realize the game-changing Internet Computer paradigm of full stack decentralization and seamless multi-chain today. Dominic Williams - Chief Scientist - Dominic's Twitter: https://twitter.com/dominic_w - Internet Computer's Website: https://internetcomputer.org/ Logan Jastremski - Co-Founder at Frictionless Capital: - Logan's Twitter: @LoganJastremski - Frictionless Capital: https://www.frictionless.fund/
n this episode, Brett Elliott (CEO of Skillwork) and Tim Raglin (COO of Skillwork) discuss the critical metrics that manufacturing companies should measure to achieve success. They highlight three broad categories of measurement: People, Performance, and Profit. Brett and Tim emphasize the crucial role of people in a manufacturing company and why it's essential to prioritize their well-being and upskilling. They also discuss the importance of tracking performance metrics such as Overall Equipment Effectiveness (OEE), Production Downtime, and Throughput, and how they impact a company's bottom line. Lastly, they touch on the traditional financial metrics that companies should measure to gauge their profitability. If you're a manufacturing company looking to improve your business operations and achieve success, this episode is a must-watch. Watch the full episode on YouTube and learn how to measure the right metrics to achieve success in manufacturing. Don't forget to subscribe and leave a comment to let us know your thoughts!
In this conversation with @DrAlanBarnard, we explore how the principles of the Theory of Constraints (originally created by Dr. Eliyahu Goldratt) can be used to not only drive significant business results but also to help us make high stake decisions as leaders. In this freewheeling conversation, we explore Dr Barnard's story about how he met with Dr. Goldratt and his famous motto. We explore who is a true expert He shares how he got into an argument with Dr. Goldratt and how he then formed a life long connection with Dr. Goldratt. He shares his most important lessons from all his interaction with Dr. Goldratt What is a Life Goal? The definition of a Life goal is a "Dream taken seriously - Dr. Eliyahu Goldratt I will not sacrifice my goal for anyone and I will not sacrifice anyone for my goal Dr. Eliyahu Goldratt He also introduces the concept of Theory of Constraint then, shares what is a constraint and the different kinds of constraints that we might face in any given system (Market/demand (external), Capacity (internal), Supply (external), Cash (Internal), Management Attention (internal) and probably the most crucial in any business. He also shares two ways to improve a constraint and therefore significantly improve your impact. He shares the importance of "Flow" or "Throughput" in any given system and how "Flow" is two-dimensional. He also shared the importance of understanding and increasing flow (time and velocity). He also shares different Ways to improve any given system. He also shares the story of how Tata Steel UK went from 1 Million Pound loss per day to 1 Million pound profit per day using Theory of constraints We constantly see good people make bad decisions. He explains why this happens and how to avoid them. He talks about what he calls as the agency equation. We then move into the realm of individuals and he shares how to identify what constrains our belief systems? Really? The power of questions - Really or unless. He also shares insights about how our minds work? He talks about the importance of learning prompt engineering to engage not just chatGPT but ourselves as well. He also shares insight on how to ask good questions as a leader and the 2 steps to make a breakthrough in any field. He also shares insight on how to measure people's performance and its impact on the business. Dr. Goldratt had started a movement called "Viable Vision". He shares more information about this viable vision and how can one go about achieving the same in their business. We then understand his own learning process and the key people he learns from - Herbert Simon and Nassim Nicholas Taleb. What is so obvious to him that all of us miss? We don't usually learn from experience but from Experiments Dr. Alan Barnard In Summary: We need to remember the 4F's - Flow, Focus, Finish and Fast Feedback to become influential and impactful leaders. More information about the resources we mentioned in the conversation: 1. Goldratt Research Labs: https://goldrattresearchlabs.com 2. Dr. Efrat Goldratt-Ashlag: / dr-efrat-goldratt-ashlag-44046212a 3. My interview with Dr. Efrat: • Delivering Projects on time, on budge... Books discussed in the video: Goldratt's Rules of Flow by Dr. Efrat Goldratt-Ashlag: https://amzn.to/3FrAa25 The Goal by Dr. Eliyahu Goldratt: https://amzn.to/3Q0iXSe Antifragile by Nassim Nicholas Taleb: https://amzn.to/3s0ieIK Blackswan by Nassim Nicholas Taleb: https://amzn.to/40d9ewz Apps mentioned by Dr. Alan Barnard: https://harmonyapps.com/apps/harmony-... Dr. Alan Barnard's podcast - https://dralanbarnard.com/category/im...
Increasing Electronic Design Automation (EDA) performance and throughput is critical to Intel's silicon Design engineers. Silicon chip Design engineers at...[…]
In today's episode Jason and Santi are joined by Logan Jastremski, Co-founder and Managing Partner of Frictionless Capital. He shares his thesis on why high-throughput blockchains are essential for crypto to reach mainstream adoption. We dive deep into the technical limitations of existing chains, and how innovations like parallelization and higher bandwidth unlock entirely new applications and business models not possible before. Stay tuned for a deep dive into deterministic and optimistic parallelization, performant validator nodes, and much more! - - Wormhole is a decentralized interoperability platform powering multi-chain applications and bridges. It provides developers with access to liquidity and users on over 30 leading blockchain networks, enabling use cases in DeFi, data queries, and governance. The platform is trusted by teams like Uniswap and Circle and, to date, the platform has facilitated the transfer of over 35 billion dollars through over 850 million cross-chain messages. Claim your unique Wormhole NFT at https://wormhole.com/empire2-9988 - - Send your crypto to your PayPal account, swap it for PYUSD, and use it to checkout at millions of stores. Pay how you want by getting started at: https://blckwrks.co/PYUSD - - Join us at DAS (Digital Asset Summit) in London this March! DAS is the #1 institutional conference in crypto, hosted by Blockworks. Use the link below to learn more, and use EMPIRE10 to get 10% off your ticket! Sign up now because the price goes up every month. See you there! Learn more + get your ticket here: https://blockworks.co/event/digital-asset-summit-2024-london/home - - Follow Logan: https://twitter.com/loganjastremski Follow Jason: https://twitter.com/JasonYanowitz Follow Santiago: https://twitter.com/santiagoroel Follow Empire: https://twitter.com/theempirepod Subscribe on YouTube: https://tinyurl.com/4fdhhb2j Subscribe on Apple: https://tinyurl.com/mv4frfv7 Subscribe on Spotify: https://tinyurl.com/wbaypprw Get top market insights and the latest in crypto news. Subscribe to Blockworks Daily Newsletter: https://blockworks.co/newsletter/ - - Timestamps: (01:35) The Logan Jastremski Thesis (08:47) Parallelization Adoption & Usecases (15:53) Blockchains at Scale (30:24) Limitations of Data Propagation (37:38) Edge Cases of Performant Blockchain Thesis (42:26) Wormole Ad (43:52) Paypal Ad (44:51) Frictionless Portfolio Decisions (48:36) Solana Criticisms (59:07) Biggest Problem Solana Faces Today (01:04:10) Applications Unlocked by High Performance (01:13:36) Investing in Private Teams vs L1 Tokens (01:16:55) Thesis Invalidation - - Disclaimer: Nothing said on Empire is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only, and any views expressed by anyone on the show are solely our opinions, not financial advice. Santiago, Jason, and our guests may hold positions in the companies, funds, or projects discussed.
Logan Jastremski, Co-founder of Frictionless Capital, sits down for an in-person podcast with Tommy to discuss scaling solutions for high throughput blockchains. They dive into integrated chains like Solana versus modular approaches like Celestia, balancing decentralization and performance, Layer 2 rollups, the differences between downtime and reorgs, and more. Logan breaks down his views from a first principles perspective and where he thinks the infrastructure is heading long-term. Join them as they unravel the future of high throughput blockchains through an enlightening exchange of ideas and expert analysis. Key Links Frictionless Capital: https://www.frictionless.fund Socials Logan's Twitter Frictionless Capital's Twitter Tommy's Twitter Follow Delphi Digital Website: https://members.delphidigital.io/home Twitter: https://twitter.com/Delphi_Digital Youtube: https://www.youtube.com/@Delphi_Digital Disclosures Disclosures: This podcast is strictly informational and educational and is not investment advice or a solicitation to buy or sell any tokens or securities or to make any financial decisions. Do not trade or invest in any project, tokens, or securities based upon this podcast episode. The host and members at Delphi Ventures may personally own tokens or art that are mentioned on the podcast. Our current show features paid sponsorships which may be featured at the start, middle, and/or the end of the episode. These sponsorships are for informational purposes only and are not a solicitation to use any product, service or token. Delphi's transparency page can be viewed here. Keywords crypto, blockchain, decentralisation, censorship resistance, transaction speeds, scalability limitations, data availability sampling, throughput bottlenecks, layer 2 rollups, sharding, virtual machines, consensus mechanisms, nakamoto coefficients, nodes, amortisation, sustainability, solana, celestia, high throughput, logan jastremski, frictionless, frictionless capital, high throughput blockchain scaling, intergrated chains,
Epicenter - Learn about Blockchain, Ethereum, Bitcoin and Distributed Technologies
What began as an AI company trying to seek solutions in order to pay remote (unbanked) workers, Near AI became, in 2018, Near Protocol. Its sharded design was inspired by modern database architecture and large language model (LLM) training. Near Protocol aimed to solve the scalability trilemma, through a modular approach, combining data availability sharding with stateless validation. By abstracting away archaic blockchain standards, Near basically enabled decentralised full stack development and, in terms of UX, a distributed custodial solution via chain abstraction and account aggregation.We were joined by Illia Poloshukhin, co-founder of Near Protocol, to discuss Near's journey, from AI company to high-throughput L1 blockchain, and how LLM training influenced the modular design choice.Topics covered in this episode:Illia's background in AI & MLScaling large language models (LLMs) and the role of attentionStochastic Parrot vs. Understanding spectrumFrom Near AI to Near Protocol and the role of LLMsHow Near abstracted the blockchain away and enabled decentralised full stack developmentDefining ecosystem standards to improve UXChain abstraction, account aggregation and interoperabilityChain threshold signatureNear's intent layerNear's modularity, Nightshade sharding & stateless validationEigenLayer integrationEpisode links:Illia Polosukhin on TwitterNear Protocol on TwitterSponsors:Gnosis: Gnosis builds decentralized infrastructure for the Ethereum ecosystem, since 2015. This year marks the launch of Gnosis Pay— the world's first Decentralized Payment Network. Get started today at - gnosis.ioChorus1: Chorus1 is one of the largest node operators worldwide, supporting more than 100,000 delegators, across 45 networks. The recently launched OPUS allows staking up to 8,000 ETH in a single transaction. Enjoy the highest yields and institutional grade security at - chorus.oneThis episode is hosted by Meher Roy. Show notes and listening options: epicenter.tv/529
12-17-2023 Rev. Keith Maxwell
Ethereum validators are earning yield for nearly a million wallets but what happens if you can restake that ETH for even more yields? Eigen Layer is one of the most ambitious projects in crypto and crossed a billion dollars in deposits while recording this episode. Joining us today is special technical co-host Mike Neuder to discuss all things Eigen Layer with Sreeram and Teddy from the team. -----
Epicenter - Learn about Blockchain, Ethereum, Bitcoin and Distributed Technologies
With an average block time of 5 seconds and sub-cent transaction gas fees, Celo focuses on scalability and ease of access in order to bring DeFi to those that need it the most. Celo's vision of ensuring equal access is reflected through their mobile-first design, aiming to disrupt legacy TradFi. The upcoming transition to an optimistic L2 rollup aims to tap into Ethereum's security, while maintaining minimal costs through Celo's scalability and EigenLayer's data availability solutions.We were joined by Marek Olszewski & Rene Reinsberg to discuss Celo's mobile-first approach to building a low-fee, high-throughput blockchain with real-world applications, and their transition to OP L2.Topics covered in this episode:Rene's and Marek's backgroundsCelo's design principlesCelo's scalabilityMobile compatibility for blockchains and dAppsWallet UXStablecoins as gas token & transaction confirmation timesOptimising mobile accessibilitySocialConnect & off-chain social identifiersCelo's transition to an Ethereum OP L2Single block finality in an optimistic rollupSequencer decentralisationLowering costs of settling on Ethereum via EigenDACredit Collective & Impact MarketMento DAOThe future of CeloEpisode links:Marek Olszewski on TwitterRene Reinsberg on TwitterCelo on TwitterMiniPay on TwittercLabs on TwitterCredit Collective on TwitterImpact Market on TwitterMento Labs on TwitterSponsors:dYdX Foundation: The recently launched dYdX chain features new governance and token economics, that empower stakers and promote validator decentralisation. Bridge your DYDX tokens and contribute to the evolution of dYdX chain, fully permissionless and community driven. - https://bit.ly/47kqG59This episode is hosted by Friederike Ernst. Show notes and listening options: epicenter.tv/524
In the ever-evolving field of marketing, the challenge has always been optimizing the marketing mix. We were fortunate to discuss this complex topic with Prof. Koen Pauwels, a renowned marketing expert at Northeastern University and co-founder of the Data Initiative. His insight provided us with valuable guidance on how to approach and refine our marketing strategies. Topics discussed: The Power of a Framework: Input, Throughput, and Output Use a basic framework for marketing mix optimization: input, throughput, and output. Align marketing goals with business objectives to chart a path to success. Understand business goals like growth or resource constraints and adjust your marketing efforts accordingly. Track hard metrics like sales to ensure alignment with these objectives. The Myth of ROI as a Silver Bullet Metric Avoid solely relying on ROI; it's an efficiency metric that can mislead you into reducing marketing investments and harming growth. Look instead at effectiveness metrics like profits and sales, which offer a better benchmark. The Role of Content and Creativity Creative content is more important than the channel used for its delivery. A well-crafted message is a primary driver of advertising effectiveness. Content Marketing Alignment of your content with the consumer's purpose for the website visit is key. In-depth integration can effectively boost your campaign. Frequency and Timing: A Delicate Balancing Act No universal rule for frequency and timing in campaigns is available. The traditional wisdom of minimum exposures has evolved with today's digital consumer behaviors. Testing and data collection can help identify the optimal frequency and reach.
Rural communities have long been touted for their remarkable resilience, and the same spirit is echoed in the hospitals in these communities. Many rural health leaders have a passion for serving the community they live in, and the resilience to keep healthcare accessible. Join us on this Episode of Rural Health Leadership Radio, where we hear from a resilient leader herself, Lili Petricevic MBA, BSN, and CEO of Sheridan Community Hospital in Sheridan, Michigan. Lili shares some of her leadership traits that made the success of Sheridan Community Hospital possible. We also discuss how she builds connections and relationships with the frontline caregivers at her hospital. “Things can change, if you do a good assessment and have good determination of where you want to be you can do it. “ -Lili Petricevic Lili Petricevic, MBA, BSN is the CEO of Sheridan Community Hospital since 2020. She was born in former Yugoslavia, Slovenia where she completed her education in Nursing and attended the University of Edvard Kardelj in Ljubljana. After immigrating to the United States and marrying a US military veteran, she received her BSN from the University of Detroit-Mercy and later her MBA with a concentration in healthcare from Davenport University. Since Lili settled in Michigan in 1992, she held various bedside RN positions ranging from rehabilitation, and med surg to Trauma Neuro intensive care. Her leadership positions as Manager and Director span from Nursing Departments, Care Management, Utilization Management, Home Care, Patient Care Logistics, and Throughput to third-party payer Medical Operations and Prior authorization divisions. In addition to these leadership roles, she has worked on the Tur-State IHI projects related to decreasing acute-level readmissions. Overall, Lili is extremely passionate about patient-focused healthcare services and finding opportunities to improve our healthcare system today. In her personal time, she enjoys spending time traveling with her husband Mark, and two daughters Jelena and Tiana.
Hudson Valley Horror Month continues when we pay a visit to Smalley's Inn in Carmel, NY. Throughput the years, there have been a number of paranormal encounters reported to have taken place within the walls of this small Putnam County tavern. It seems to have all started when the owner found the grave of a young girl buried under a set of steps in the tavern. From there, things only intensified. Join us next week, as we examine these claims! Become a Patron: https://patron.podbean.com/betweenthecrackspodcast Follow the link for our special offer of 20% off of Magic Mind: https://www.magicmind.com/btc
While many global genomics analyzes gene variants or RNA expression products, the levels of proteins are usually the most informative. At the same time, quantifying proteins is relatively difficult, especially when trying to obtain a snapshot of the proteome from a single cell or tissue. Dr. Parag Mallick of Stanford University and Nautilus Biotechnology describes the utility of high-throughput proteomics, and how the technology incorporates a novel detection method and machine learning to quantify large suites of proteins. The applications are almost endless and present great opportunities to understand how accumulation of specific proteins relates to biological function or disease states.