Podcasts about Bordetella

Whooping cough, also known as pertussis, is a highly contagious respiratory infection caused by the bacteria Bordetella pertussis. It's characterized by severe, persistent coughing fits, often ending with a high-pitched "whoop" sound. The disease can be very serious, especially for infants, and is preventable through vaccination. ​​​Whooping cough is an illness that can spread easily. It's also called pertussis. An infection with bacteria causes it. Many people with the illness get a serious hacking cough. Breathing in after coughing often causes a high-pitched noise that sounds like a "whoop." ​Before the vaccine for pertussis came out, whooping cough was thought of as a childhood disease. Today, whooping cough mainly affects children too young to have gotten all their shots of the vaccine. The illness also tends to affect teenagers and adults whose protection from the vaccine has faded. ​Deaths linked with whooping cough are rare. Most often, they occur in infants. But pregnant people can help protect their babies by getting a booster shot of the vaccine during pregnancy. Vaccination also is recommended for other people who will have close contact with an infant. ​Once you become infected with whooping cough, it takes about 5 to 10 days for symptoms to start. Sometimes it takes up to three weeks. The symptoms often are mild at first. They may seem like those of a common cold. They can include: Runny or stuffy nose. Red, watery eyes. Fever. Cough. ​​After a week or two, the symptoms become worse. Thick mucus builds up inside the airways. This causes rapid coughing that can't be controlled. The cough can last for weeks or months, and it may be worse at night. Intense coughing attacks may cause: Vomiting. A red or blue face. Extreme tiredness. A high-pitched "whoop" sound during the next breath of air. ​People with mild illnesses often don't make the whooping sound. Sometimes, an ongoing hacking cough is the only symptom of whooping cough in teens and adults. ​Many babies with the illness don't cough at all. Some babies and young children might. Gag or struggle to breathe. Have skin, lips or nails that turn blue or purple. Have life-threatening pauses in breathing called apnea. (credits)

En entrevista con Juan Manuel Jiménez para MVS Noticias, en ausencia de Manuel López San Martín, el doctor Mauricio Rodríguez, profesor del Departamento de Microbiología y Parasitología de la Facultad de Medicina de la UNAM, lanzó una seria advertencia sobre la creciente presencia de la tosferina en México: “Lo que estamos viendo de tosferina es un fenómeno muy complejo que está pasando en varios estado del país”, sentenció. ¿Qué es la tos ferina y cómo distinguirla? La tosferina, enfermedad causada por la bacteria Bordetella pertussis, ha cobrado la vida de al menos 45 menores en el país, y aunque muchos piensan que solo afecta a niños, el doctor aclara que “es una enfermedad que se puede presentar en todas las edades”. “La tosferina es una enfermedad que su rasgo distintivo es producir una tos que tiene unas características peculiares, una tos que produce un ruido como de perro, y eventualmente, puede provocar problemas respiratorios, sobre todo en los más pequeñitos”; explicó.See omnystudio.com/listener for privacy information.

Send us an inquiry through a text message here!Welcome to another episode of The Veterinary Roundtable! In this episode, the ladies discuss the challenges of treating patients at a higher elevation, a handful of My Pets Wellness clinics closing overnight, keeping antimicrobial resistance in mind when treating patients, and more!Do you have a question, story, or inquiry for The Veterinary Roundtable? Send us a text from the link above, ask us on any social media platform, or email theveterinaryroundtable@gmail.com!Episodes of The Veterinary Roundtable are on all podcast services along with video form on YouTube!Instagram: https://tinyurl.com/2h27xnfuTikTok: https://tinyurl.com/m8f62ameYouTube: https://tinyurl.com/48njfywdTIMESTAMPSIntro 00:00Pits And Peaks 04:34Tails From The Trenches 11:32My Pets Wellness Closes All Vet Clinics Overnight 16:50New Immunotherapy Treatment May Delay Metastasis In Dogs With Osteosarcoma 21:18Case Collections 23:36Listener Loves Intranasal Bordetella 31:10Treating Patients At A Higher Elevation 34:00Keep Antimicrobial Resistance In Mind When Treating Patients 37:44Outro 44:28

En entrevista para MVS Noticias con Ana Francisca Vega, la Dra. Rosa María Wong, académica de la Facultad de Medicina de la UNAM, habló sobre que aumentan casos de tos ferina en México un mil 500 por ciento en 2025, síntomas y medidas de prevención. "La tosferina es una enfermedad bacteriana, casusa por la bacteria Bordetella pertussis, esta bacteria puede causar en niños muy pequeños, tos, una tos que se le llama paroxística, o en accesos, cuando empieza a toser, y a toser, y a toser, en accesos de tos tan importantes que los bebés se ponen morados, a veces dejan de respirar y puede causarles una neumonía que puede ser grave, sobretodo en los bebés muy pequeñitos", dijo. Comentó que en el caso de los adultos, puede tratarse de una tos crónica, así que las personas que tienen tos de más de dos semanas de evolución, puede ser esa la enfermedad.See omnystudio.com/listener for privacy information.

Whooping cough is spreading around the country. This is just the latest epidemic of this highly contagious bacterial illness that has seen a large resurgence over many years now. Here are the questions we address:What is whooping cough? What are the symptoms? How contagious is it? How is it treated? What can I do to prevent it?

Today we are going to give you the scoop on whooping cough, also known by the less friendly name, pertussis, the infection caused by the crafty and toxin-producing bacteria Bordetella pertussis. According to data from the CDC, rates of whooping cough are currently 3X higher than in 2023 and still climbing. Why? Listen and find out.Visit us at OnMedicalGrounds.com for more podcasts or download our app! You can subscribe through your podcast platform, our website, or follow us on social media for podcast updates and medical news. Some of our podcasts offer FREE CME/CE credits.LinkTreeLinkedInInstagram

In this episode, we dive into the world of whooping cough (pertussis). Whooping cough is a highly contagious bacterial respiratory infection caused by Bordetella pertussis. It is characterized by severe coughing fits that can make breathing difficult, often accompanied by a distinctive high-pitched “whoop” sound during inhalation. It often begins with mild cold-like symptoms, which […] The post Homeopathic Strategies for Support During Whooping Cough appeared first on Ultimate Homeschool Podcast Network.

Kolem očkování se objevují různé mýty a hoaxy a rodiče často pod vlivem dezinformací na sociálních sítích odkládají očkování svých dětí a hazardují tak se zdravím celé populace. S profesorem mikrobiologie a vedoucím laboratoře molekulární biologie bakteriálních patogenů Mikrobiologického ústavu AV ČR Petrem Šebem se dnes podíváme na časté mýty týkající se očkování a na to, co říkají vědecká fakta. Dnešní epizoda vznikla díky podpoře ‪ @WHORegionalOfficeforEurope Podívat se na ní můžeš také na Youtube. Co se v epizodě dozvíš?

You'll be whooping with knowledge after listening to this one. Come hear all about Bordetella species. From pertussis to kennel cough you'll hear it all.Show notes for this episode hereSend us a Text Message. Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Com alguns casos de Coqueluche sendo reportados nos boletins epidemiológicos , William e Mafê fazem uma revisão sobre os aspectos dessa doença também conhecida com tosse comprida. Nessa episódio conversamos sobre as vacinas, aspectos clínicos, tratamento e mais sobre a doença causada pel bactéria Bordetella pertussis.

Your Furry Friend this week is Bailey from Berrien County Animal Control. Bailey came to us as a skinny and pregnant young dog. She was a great mama and all of her puppies have been adopted, so now it's all about Bailey! Bailey has a gray coat and is sleek and well muscled, weighing in at around 60 pounds. We think she is house-trained! Bailey gets along with most other dogs, loves to run with friends in the play yard, and is very treat motivated. Through the end of March, all of our adult dogs-- including Bailey --are just $17.00 to adopt! Spayed/Neutered, micro-chipped heartworm tested (Bailey is negative!), and up-to-date on vaccines. You can meet Bailey and her 30 available furry friends at Berrien County Animal Control, 1400 South Euclid Avenue, Benton Harbor, MI 49022. No appointments necessary during the week. For weekends, please call 269-927-5648 in advance to schedule an appointment. Talking Points:   Sunday, April 21st, 10am to 2pm - Vaccine Clinic at Weesaw Township Fire and Rescue: $20 1-year Rabies, $25 3-year Rabies. $25 Distemper combo vaccine. $25 Bordetella. $25 Microchips.  1 year dog licenses $12 altered /$27 unaltered 3 year $27 altered /$72 unaltered,  Pre-register on the Berrien County website or call us at (269) 927-5648.  Cash only.  Dogs must be leashed and cats must be in carriers. See omnystudio.com/listener for privacy information.

¿Has escuchado sobre la tos de perrera? Es una enfermedad respiratoria altamente contagiosa que se puede propagar de un perro a otro a través del contacto directo o por el aire; la causa más común es la presencia de la bacteria Bordetella bronchiseptica.

A mystery dog illness that spread across the U.S. last year and can lead to serious or fatal respiratory problems is still under investigation, but cases are starting to slow, experts say. The illness, which started to spread more widely in the summer and fall of 2023, causes coughing, sneezing and fatigue, among other symptoms, and can progress quickly to pneumonia. The dogs suspected to have it test negative for all of the typical causes of respiratory symptoms and often don't respond to treatment. In a statement to TODAY.com, the American Veterinary Medical Association says that based on "conversations with various sources ... the number of cases are declining," adding that an "ebb and flow" of respiratory illness in dogs over the course of the year is common, similar to cold and flu season in humans. The statement also explains that the U.S. Department of Agriculture has so far not seen that the rise in respiratory illness in dogs is linked to a new virus or bacteria. A statement from the Animal and Plant Inspection Service, part of the USDA, confirms to TODAY.com that the state-led testing that the agency is helping coordinate "has not indicated the presence of a novel pathogen or single infectious cause among these cases." Numerous veterinary diagnostic labs across the country are investigating the outbreak, from Oregon to Kansas to New Hampshire. The APHIS spokesperson adds that the illness is not regulated by APHIS and therefore the branch doesn't have data on case numbers. The Oregon Veterinary Medical Association also shared in an Feb. 14, 2024, update that "cases seem to be waning, if not back to normal," citing veterinarian Dr. Scott Weese's Worms and Germs blog. At last count, at least 19 states had reported cases of the illness, according to various expert groups. The AVMA explained in an earlier statement that the mystery dog illness is difficult to track because there's no national surveillance system. In November 2023, veterinarians in critical care settings told TODAY.com that they'd seen dozens of cases since the fall. Late last year, multiple groups — including the Colorado and Oregon departments of agriculture, the AVMA, the Rhode Island Department of Environmental Management and the Los Angeles County Department of Public Health — issued warnings about the mystery illness in dogs. “We don't know what is causing this situation, where dogs are presenting at veterinarians with what private veterinarians would call kennel cough,” Rhode Island's state veterinarian Dr. Scott Marshall told NBC affiliate WJAR. “What's different about this situation is that dogs are presenting with little bit more severe signs, not responding to usual treatments, and unfortunately had a small number, still a number, of dogs that have succumbed to them.” “It seems to happen very, very quickly — to go from this cough that's just won't go away ... and then all of a sudden they develop this pneumonia,” Dr. Lindsey Ganzer, veterinarian and CEO at North Springs Veterinary Referral Center in Colorado Springs, Colorado, told TODAY.com. She said she treated over a dozen dogs with what she believes is the condition between October and November 2023. If your dog develops a cough, do not panic, the AVMA advises. But stay vigilant about its progression and your pet's overall health, and contact your vet right away if anything seems off. What is the mystery dog illness? Dogs with this mystery illness usually have coughing, sneezing, eye or nose discharge, are abnormally tired, and do not test positive for any common causes of canine respiratory illness, the Oregon Department of Agriculture noted in a Nov. 9 press release. Typically, dogs with respiratory illnesses have a cough for seven to 10 days, but some vets saw an uptick in dogs with coughs lasting weeks to months that don't respond to treatment, the Colorado Department of Agriculture said in a Nov. 22 statement. One of the distinguishing characteristics of this mystery illness outbreak was the high number of dogs who developed pneumonia. One Colorado vet, Dr. Michael Lappin, director of the Center for Companion Animal Studies at the Colorado State University School of Veterinary Medicine, told NBC News the number of canine pneumonia cases in the state rose by 50% between September and November 2023 compared to 2022. Marshall estimated that Rhode Island saw at least 35 cases of the mystery respiratory illness, but it's hard to know exactly how many because not all cases are reported. Dogs are most likely to contract it by being in close contact with numerous other dogs — so places like doggy day care, dog parks, groomers or boarding kennels, Ganzer said. The illness seems to affect dogs regardless of age, size or breed, though dogs with snort snouts, like bulldogs and pugs, may be at higher risk. Between mid-August and mid-November, the Oregon Department of Agriculture received reports of over 200 cases of the illness from veterinarians in the state but has had no additional cases to report since. A Dec. 1 statement from the Washington Department of Agriculture said the state has received 16 reports of unusual canine respiratory disease. Two cases were confirmed as such. The Colorado Department of Agriculture also shared in November that veterinarians in the state were seeing "double the number of cases than what is typically seen during a canine infectious respiratory disease outbreak."   The Wisconsin State Journal reported that between late October and December, clinics around the state saw six to 12 cases each, according to Dr. Keith Poulsen, director of the Wisconsin Veterinary Diagnostic Laboratory at University of Wisconin-Madison. Dr. Amanda Cavanagh, head of urgent care services at Colorado State University James L. Voss Veterinary Teaching Hospital, in Fort Collins, Colorado, told TODAY.com that this past summer she started seeing cases of dogs with coughs lasting several weeks or longer, and the trend continued into the fall. She estimated her caseload of coughing dogs doubled from October to November. While dogs with a contagious cough are common in veterinary settings, Cavanagh noted that she normally sees cases decrease in the fall as temperatures drop and fewer dogs are gathering at parks. "But this year, the spike has stayed high," she explains. In its original press release, the Oregon Department of Agriculture noted that the illness can progress in three ways: Mild to moderate cough for six to eight weeks or longer that either doesn't respond to antibiotics or only responds a little Chronic pneumonia that doesn't respond to antibiotics Severe pneumonia that "often leads to poor outcomes in as little as 24 to 36 hours" Cavanagh witnessed all three scenarios play out at her hospital. Last fall, she said she saw more dogs than usual with a long-lasting upper respiratory infection who then developed pneumonia from a secondary bacterial infection. Of the dogs she treated, she said most who developed pneumonia responded to antibiotics, and many with the long-lasting cough recovered with time and never got pneumonia. But of those who developed the severe pneumonia, some died or had to be euthanized. "That really bad pneumonia, historically, is very, very rare. Maybe I would see one case a year," but last fall alone, Cavanagh saw a "handful," she said. How many dogs have died from the mystery illness? Because most states are not tracking case numbers, it's not known exactly how many dogs have died from the illness. The Oregon Department of Agriculture tells TODAY.com that it does not know how many dogs have died from the illness in the state. However, it is confirmed that some dogs in the U.S. have died from the mystery illness. The Colorado Department of Agriculture said in a statement that "in rare cases, the canine patients progress quickly from pneumonia to death." Colorado State University College of Veterinary Medicine and Biological Sciences also said the illness has resulted in "some fatalities." Ganzer and Cavanagh both have had several canine patients die from what they believe to be the condition. Rhode Island Veterinary Medical Association President Shelly Pancoast told WJAR that she's seen five to 10 dogs die from the mystery illness. “We still don't have a great handle on how exactly we should be treating these dogs,” Pancoast said. “A vast majority of them are making full recovery, it's just unlike anything we've seen in previous years with kennel cough." What states have the mystery dog illness? According to various expert groups, cases that match the description of the mystery dog illness have been reported, officially or anecdotally, in: Colorado California Florida Georgia Idaho Illinois Indiana Maine Maryland Massachusetts New Hampshire Nevada Oregon Pennsylvania Rhode Island Tennessee Vermont Washington Wisconsin This above list of states comes from the AVMA, the Tennessee Veterinary Medical Association, the Louisiana State University School of Veterinary Medicine and the Wisconsin Veterinary Diagnostic Laboratory at University of Wisconsin-Madison. Mystery dog illness 2023 symptoms Symptoms of the mystery dog illness include: Coughing that doesn't get better on its own after a week or so Sneezing Nasal or eye discharge Red eyes Lethargy Trouble breathing, especially from the stomach Blue or purple gums (due to not getting enough oxygen) Related: What does coughing in a dog sound like? Vet explains in viral video Signs of coughing in dogs For many dog owners, the signs of coughing can be difficult to recognize, Dr. Michele Forbes, Dr. Michele Forbes, owner of Compassionate Care Hospital in Ann Arbor, Michigan, says. "Rarely do (dog owners) identify a cough until it becomes an overt problem and it's clearly coming from the chest,” Forbes explained in a now-viral TikTok. As a result of owners not noticing coughing or confusing it for something else, like throat-clearing or gagging, some dogs are arriving at vet facilities in more advanced stages of the condition, which can make it more difficult to treat, Forbes told TODAY.com. Some tips to help identify signs of coughing in dogs: The sound dogs make when they're choking can be confused for coughing. Some dogs sound like they're honking, kind of like a goose. Coughing can also sound like the dog is gagging or clearing its throat. The chest may heave or the abdomen may move while the dog is coughing. For some dogs, it looks like they're trying to cough up a hair ball and they may produce some liquid. A wet cough may produce a gargling sound. If a dog is coughing a lot, they may end up vomiting, which dog owners often confuse for a gastrointestinal issue. Reverse-sneezing can be confused for coughing but it's not usually a reason to call the vet unless it's paired with actual coughing, nasal discharge or any other concerning symptoms. When to see the vet for the mystery dog illness Other signs that your dog should see the vet, per the AVMA, include: Lingering cough Weakness Loss of appetite Difficulty breathing Worsening of illness Cough that is sufficiently severe that it causes the dog to vomit or makes it hard for the animal to breathe Tips to prevent mystery dog illness from vets Dogs are most likely to contract the illness when in close contact with other dogs, so previous guidance was to keep dogs away from other dogs. But case rates have essentially returned to normal, Weese noted in his blog. To keep your dog safe and healthy overall, the AVMA recommends keeping up to date with vaccinations. "While the existing vaccines may not specifically target this unknown infection, maintaining overall health through routine vaccinations can help support a dog's immune system in combating various infections," it said. The AVMA stressed the following vaccines: Bordetella, Adenovirus type 2, and parainfluenza combined with the injectable influenza H3N2 vaccine. Be sure to give your dog two weeks after vaccination before interacting with other dogs so they can build up immunity. If your dog is sick, consult a vet as soon as possible, as early testing can help with treatment, and keep the dog away from other dogs to avoid spreading the illness, experts advise. While it's unlikely a humans can get sick with the respiratory illness, because the cause is still unknown, the AVMA suggests thoroughly washing hands after handling any dogs. Caroline Kee contributed reporting.

Visit our website: lovedog.com for in-depth articles, adoptions, and great online shopping!Shop for the pup in our store: Woof & Wear: The ShopShow SponsorThis Episode is sponsored by Fig & Tyler, makers of one-ingredient, human grade dog treats . . . a favorite among professional dog trainers!DescriptionIn Episode 3, Hosts, Mark Drucker and Drew Webster, discuss dog vaccines with Dr. Ng. They break down the different types of vaccines, including modified live, killed, and recombinant. Emphasis is placed on which vaccines to think of as “core” such as rabies, parvo, and distemper, while categorizing others as optional, as they depend more on geographical and lifestyle factors. They also address the concerns of people who tend to be vaccine-hesitant and the importance of informed conversations with veterinarians.Dr. Ng discusses specific dog vaccines that may be considered optional, including Bordetella, Leptospirosis, Canine Influenza, and Lyme Disease, and he provides insights on public health concerns as well as the symptoms and dangers of each disease should a dog contract them.Disclaimer: Our podcasts are for your entertainment and general information purposes only. We often interview veterinarians, scientists, behavior consultants, dog trainers, etc. You must always consult with your own canine and pet practitioners before implementing any training program or course of medical diagnosis and/or treatment. Links From The EpisodeFig & TylerRabies awareDr. Zenithson Ng, University of TennesseeBuy us a cup up coffee! Support the podcast!Chapters00:00 Show opens02:30 Introducing the Hosts03:30 Interview with Dr. Ng11:03 Understanding Different Types of Vaccines24:03 Importance of Puppy Boosters30:31 Breaking Up Vaccines for Better Dog Experiences36:31 Core Vaccines vs. Optional Vaccines38:26 Description of Core Vaccines49:11 Description of Non-Core Vaccines51:32 Bordetella Vaccine and Lifestyle52:30 Lifestyle and Vaccination Choices55:13 Leptospirosis and Wildlife Exposure58:01 Leptospirosis and Risk Factors58:58 Letting Dogs Be Dogs and Vaccine Choices01:00:51 Canine Influenza and Vaccine Recommendations01:02:48 Lyme Disease and Vaccine Considerations01:04:43 Lyme Disease Misdiagnosis and Vaccine Efficacy01:06:04 Tick Prevention and Vaccination01:08:01 Vaccination for Senior Dogs01:14:13 COVID-19 and Dogs01:15:37 mRNA Vaccines for Dogs01:18:18 Mysterious Respiratory Virus01:22:26 Prevention for Boarding and TravelConnect with Love, DogFollow us on Instagram: @lovedognews Email us with questions, comments, and suggestions: podcast@lovedog.com

In this episode, we review the high-yield topic of⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠Bordetella pertussis⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Microbiology section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbull --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message

Do you ever wonder how vaccines protect your beloved pooch from preventable diseases? Dr. Natalie Craven from Pinellas Animal Hospital has returned to our show to decode the science behind vaccines and their significance in ensuring your pet's health. This episode is packed with crucial information about core vaccines for puppies and how they safeguard our pets against diseases like rabies, distemper, and parvovirus.We bring to light common misconceptions about diseases like kennel cough, and how vaccination, along with safe socializing practices, can help keep these at bay. Our discussion extends to the alarming realities of Lyme disease in Florida and its impact on our dogs. Dr. Craven stresses the importance of the Lyme vaccine, and others such as leptospirosis, canine influenza, and bordetella. We also tackle the rising anti-vaccination sentiment and the importance of re-evaluating vaccines in the veterinary field.Towards the end of our conversation, we delve into the situations when a dog may not be suitable for vaccination, taking into account factors such as age, illnesses, and the effects of chemotherapy. Dr. Craven shares valuable insights on the risks and side effects of vaccinations in pets, emphasizing the importance of consulting with a veterinarian before proceeding. We conclude the episode with a compelling discussion about titer testing and why investing in vaccines is paramount for your pet's well-being. Don't miss out on this enlightening episode that promises to deepen your understanding of the vital role vaccines play in your pet's health and longevity.Dr. Craven's practice;https://pinellasvet.com/For more information on vaccines;https://www.avma.org/resources-tools/pet-owners/petcare/vaccinationshttps://www.lifelearn-cliented.com/iframe.php?action=view&clinic=350&rid=841&c=63716-20230830184420-259b8ad96970fe1632090e702dee3515&print=1https://www.aaha.org/globalassets/05-pet-health-resources/vaccination_poster2.pdfHave you ever thought about capturing professional portraits of your furry family member? If so, we're here for you? Urban Dog Studio, Tampa Bay's premiere pet photography studio, specializes in stunning portrait sessions in the studio, on location, and even in the water! Whether you're in St. Petersburg, Tampa, Clearwater, Bradenton, Sarasota, or any of the beach communities, Urban Dog Studio is here for you. Contact Urban Dog Studio today, and let them work their magic to bring out the best in you and your pets.

Pertussis (also known as “whooping cough”) is a respiratory tract infection caused by the bacteria Bordetella pertussis. It is a highly contagious disease that predominantly impacts children. In this episode you'll learn the key things you know about pertussis: * Pertussis pathophysiology and stages of disease * The pertussis vaccine * Complications of pertussis * Signs and symptoms of pertussis * Key nursing assessments for a patient with pertussis * Tests that will be ordered * Treatments for pertussis * Important patient education information To learn more about respiratory distress in children, listen to Episode 140. And, to dive into ECMO, you can read more about it here. Read the article Pertussis Basics for Nursing Students and view references here. Review pediatric topics on the go with Study Sesh! Study for your nursing school exams and NCLEX on the go with over 90 PodQuiz episodes covering a wide range of topics. Sign up for Study Sesh here! If this episode helped you, please take a moment to rate and review the show! This helps others find the podcast, which helps me help even more people :-) _____________________________________ The information, including but not limited to, audio, video, text, and graphics contained on this podcast are for educational purposes only. No content on this podcast is intended to guide nursing practice and does not supersede any individual healthcare provider's scope of practice or any nursing school curriculum. Additionally, no content on this podcast is intended to be a substitute for professional medical advice, diagnosis or treatment. Straight a Nursing is a proud member of the Airwave Media Network. Learn more about your ad choices. Visit megaphone.fm/adchoices

CME link for Episode 26: Stress About Strep: What to Do When It Won't Go Away https://cmetracker.net/UTHSCSA/Publisher?page=pubOpen#/getCertificate/10092937Stress About Strep: What to Do When It Won't Go Away FACULTY: Theresa (Tess) Barton, MD is a pediatric infectious disease doctor with UT Health San Antonio and University Hospital.  She is passionate about working with adolescents with HIV, and that interest has evolved.    OVERVIEW: Pediatrics Now Host and Producer Holly Wayment interviews Tess Barton, MD about what to do when strep keeps coming back or won't go away. Wayment and Dr. Barton also discuss a new pertussis concern. Doctor/Provider/Clinic Staff to Infectious Disease Doctor Number: 210-890-2699 Referral Info: OCCAPI Clinic: Diagnostic testing and treatment of congenital infections including: CMV, syphilis, hepatitis B, hepatitis C and HIV Located at UH Rio Tower Dr. JB Cantey   FFACTS Clinic: Testing and prophylaxis for newborns exposed to HIV infection Treatment and primary care services for children and adolescents living with HIV infection Comprehensive care with case management and mental health services Dr. Tess Barton PEDIATRIC INFECTIOUS DISEASES CLINIC UH Rio Tower, Drs. Barton and Cantey   We see a variety of infections and communicable diseases, as well as follow-up care after hospitalization for severe infections. That includes follow-up after severe COVID infections, or long-term COVID illnesses.   DISCLOSURES: Theresa (Tess) Barton, MD has no financial relationships with ineligible companies to disclose.   The Pediatric Grand Rounds Planning Committee (Deepak Kamat, MD, PhD, Daniel Ranch, MD and Elizabeth Hanson, MD) has no financial relationships with ineligible companies to disclose.  Planning Committee member Steven Seidner, MD has disclosed he receives funding from Draeger Medical for the Clinical Study to Evaluate the Safety and Effectiveness of the Infinity Acute Care System Workstation Neonatal Care Babylog VN500 Device in High-Frequency Oscillatory Ventilation (HFOV) Mode in Extremely Low Birth Weight (ELBW) Neonates for which he is a co-principal investigator. The relevant financial relationships noted for Dr. Seidner have been mitigated.     The UT Health Science Center San Antonio and Deepak Kamat, MD course director and content reviewer for the activity, have reviewed all financial disclosure information for all speakers, facilitators, and planning committee members; and determined and resolved all conflicts of interests.   CONTINUING EDUCATION STATEMENTS: The UT Health Science Center San Antonio is accredited by the Accreditation Council for Continuing Medical Education to provide continuing education for physicians.   The UT Health Science Center San Antonio designates this live activity up to a maximum of 0.50 AMAPRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.   CREDITS: AMA PRA Category 1 Credits™ (0.50) Non-Physician Participation Credit (0.50)  

BSAVA president Alison Speakman and vice-president Carl Gorman join the Vet Times Podcast to look forward to BSAVA Congress 2023, being held from 23-25 March in Manchester. Dr Speakman provides an update on some of the association's recent activities, and looks forward to what will be the first BSAVA Congress since 2019 to be held as a fully face-to-face event. She also looks at key discussions taking place at congress – including the neurodiversity stream on Friday 24 March – and discusses the expansion of the Wellbeing Zone, which debuted last year. Mr Gorman will become BSAVA president in the summer, and in this podcast discusses some of his priorities and ambitions for the year ahead. He also explains how the BSAVA is aspiring for congress to be a carbon-neutral event, as part of the association's ongoing sustainability initiatives. _________________________________

3.15 Bordetella Pertussis Microbiology review for the USMLE Step 1 exam Bordetella pertussis is a gram-negative bacterium that causes whooping cough Spread through respiratory droplets, most people are vaccinated against it Adheres to ciliated respiratory epithelial cells and produces toxins that cause inflammation and systemic effects Pertussis toxin and tracheal cytotoxin are important toxins secreted by the bacteria Symptoms include four stages: incubation, catarrhal, paroxysmal, and convalescent Infants and unvaccinated people are most commonly affected Treatment is mostly supportive, including oxygen, suctioning, hydration, and avoidance of respiratory irritants.

3.04 Gram Negative Bacteria   Microbiology review for the USMLE Step 1 Exam.   Gram negative bacteria are characterized by a thin cell wall surrounded by a lipid outer membrane They do not retain the violet gram stain and appear pink after staining Gram negative bacteria can be classified by shape: cocci, coccobacilli, bacilli, and spirals Gram negative cocci include Neisseria species, which can be further categorized as maltose fermenters or non maltose fermenters Gram negative coccobacilli include: Bordetella pertussis, Haemophilus influenzae, Pasteurella, Francisella tularensis, Brucella, and Acinetobacter Gram negative bacilli can be divided into lactose fermenting and non lactose fermenting categories Lactose fermenting gram negative bacilli include: Escherichia coli, Klebsiella, Enterobacter, Citrobacter, and Serratia Non lactose fermenting gram negative bacilli can be further divided into oxidase positive and oxidase negative Oxidase positive non lactose fermenting gram negative bacilli include Pseudomonas Oxidase negative non lactose fermenting gram negative bacilli include Shigella, Yersinia, and Salmonella Gram negative spirals can be divided into oxidase positive and oxidase negative categories Oxidase positive gram negative spirals include Vibrio species, Helicobacter pylori, and Campylobacter jejuni Oxidase negative gram negative spirals include Borrelia burgdorferi (cause of lyme disease) and Treponema pallidum (cause of syphilis)

In today's VETgirl online veterinary continuing education podcast, we interview Dr. Morgan Kelley, DACVECC on her paper "Retrospective analysis of the use of tranexamic acid in critically ill dogs and cats (2018-;2019): 266 dogs and 28 cats." If you're not sure what tranexamic acid (TXA) is and how it works to stop bleeding, you want to tune in! Learn how TXA has been used in veterinary versus human medicine, what the indications or contraindications for it are in veterinary medicine, how you can administer it, and how you can use TXA in your day to day practice! Today's VETgirl podcast is sponsored by Merck Animal Health, makers of Nobivac® Intra-Trac® Oral BbPi, the first oral Bordetella bronchiseptica and canine parainfluenza virus vaccine with patented Immuno-Mist-R™ technology.

Following a dog flu outbreak in Nashville, TN, Dr. Natalie Marks says it can happen anywhere unless enough dogs are vaccinated. She explains signs of dog flu and why dog parents should pair up for protection with both the vaccine for dog flu and for Bordetella. Dogs as pirates seems too obvious, as Captain Gabe Argumedo of the Mercury […]

Alison Speakman will take over the BSAVA presidential chain of office when the association holds its annual meeting in May. She joined Congress Times editor Tom Jackson to discuss her aims and ambitions for the role, as well as her journey with the BSAVA. Dr Speakman has also spearheaded the creation of the Wellbeing Zone, which debuts at this year's congress being in Manchester from 24 to 26 March. In this podcast, she explains her reasons for leading the initiative and what she hopes delegates will take away from the zone. ___________________ Alison Speakman BVMS(Hons), PhD, CertAVP, MRCVS Dr Speakman qualified from the University of Glasgow in 1991 and, after a year in mixed practice in Lancashire, completed a residency in feline medicine followed by a PhD on Bordetella bronchiseptica infection. Following a short period of post-doctoral research, she returned to small animal practice in Lancashire. Apart from a two-year spell as a veterinary technical director in industry and a year in Australia, Dr Speakman has remained with her roots in the north-west for most of her working life. She currently works in a small animal practice in Lancashire and has recently completed her CertAVP. Dr Speakman first joined the BSAVA as a new graduate and has been a member ever since, joining her local regional committee in 1995 followed by spells on the education committee, congress committee and PetSavers committee, and as honorary secretary. She currently sits on the BSAVA's north west regional committee.

Algunos síntomas del resfriado pueden llegar a confundirse con el moquillo, enfermedad muy contagiosa causada por un Morbillivirus de la familia Paramyxoviridae que afecta principalmente al sistema respiratorio y que ataca a perros de todas las edades. La traqueobronquitis infecciosa canina (más información aquí), o también conocida como tos de las perreras es una enfermedad a menudo causada por la bacteria Bordetella bronchiseptica, es otra patología que presenta síntomas similares al resfriado en los perros. Para saber mas sobre las enfermedades del tracto urinario descárgate nuestra guía completa aquí: https://vetsandclinics.affinity-petcare.com/es/research-report-enfermedades-tracto-urinario-felino-parte-1-2 👉🏽 Descubre más relacionado con la dermatología - oncología Puedes apuntarte a Visita nuestro blog: https://www.affinity-petcare.com/vets... Síguenos en nuestros canales oficiales: 👉🏽 LinkedIn: https://www.linkedin.com/showcase/vet... 👉🏽 Twitter: https://twitter.com/VetsAndClinics

Algunos síntomas del resfriado pueden llegar a confundirse con el moquillo, enfermedad muy contagiosa causada por un Morbillivirus de la familia Paramyxoviridae que afecta principalmente al sistema respiratorio y que ataca a perros de todas las edades. La traqueobronquitis infecciosa canina (más información aquí), o también conocida como tos de las perreras es una enfermedad a menudo causada por la bacteria Bordetella bronchiseptica, es otra patología que presenta síntomas similares al resfriado en los perros. Para saber mas sobre las enfermedades del tracto urinario descárgate nuestra guía completa aquí: https://vetsandclinics.affinity-petcare.com/es/research-report-enfermedades-tracto-urinario-felino-parte-1-2 👉🏽 Descubre más relacionado con la dermatología - oncología Puedes apuntarte a Visita nuestro blog: https://www.affinity-petcare.com/vets... Síguenos en nuestros canales oficiales: 👉🏽 LinkedIn: https://www.linkedin.com/showcase/vet... 👉🏽 Twitter: https://twitter.com/VetsAndClinics

Welcome to another episode of the Pet Purpose Podcast, the show where my guests and I talk all things pet related… topics that help passionate pet parents take pet parenting to the next level, or topics that are simply of interest for pet parents. Our pets can at times get infections of the respiratory tract. In this episode I talk all about Kennel Cough disease in dogs:·      what is coughing·      what are the signs of Kennel Cough·      where can dogs pick up a Kennel Cough infection·      how to prevent it·      how to treat it·      and more!Enjoy the episode.This episode is brought to you by Tail Ovation, the online pet store for passionate pet parentsFor show notes and previous episodes, please visit tailovation/podcastLife is better with pets!Disclaimer: The Pet Purpose Podcast contains general information about animal health care conditions and treatments. The information is not advice, and should not be treated as such. You must not rely on the information on the Pet Purpose Podcast as an alternative to animal health care advice from your veterinarian or other professional animal care providers. If you have any specific questions about any animal health care matter you should consult your veterinarian or other professional animal care provider. If you think your pet may be suffering from any animal health condition you should seek immediate veterinary attention specific for your pet. You should never delay seeking veterinary advice specific to your pet, disregard veterinary advice, or discontinue animal health care treatment because of information on the Pet Purpose Podcast. You agree not to hold the representatives, employees, guests or affiliates of the Pet Purpose Podcast, liable for any damages arising from or relating to your reliance on any of the animal health care information provided on the Pet Purpose Podcast. Additionally, you agree not to repeat the animal health care information that you consume on the Pet Purpose Podcast to a third party, as that third party may not have read this disclaimer and understood the caveats involved in receiving the information.

The COVID-19 pandemic has affected us all in many ways, and one of the effects we have seen is the impact on the human-animal bond. In this Vet Times Extra podcast, Jon Bowen, behaviour consultant at the RVC, discusses the behavioural problems seen during the pandemic and the impact these have had on owners, as well as vets and vet nurses. Dr Bowen also talks about the importance of canine infectious respiratory disease complex (CIRDC) vaccination when our canine patients are returning to socialising again, and how we can make these veterinary visits less stressful for the dogs, their owners and the veterinary team. ______________________ Jon Bowen graduated from the RVC in 1992 and spent several years in general practice. He is behaviour consultant at the RVC's Queen Mother Hospital for Animals, and sees referral cases from all over south-east England. He is currently newsletter editor for the Companion Animal Behaviour Therapy Study Group, and has coauthored a text book of behavioural medicine. ______________________ SPONSORED This podcast is sponsored by Zoetis, makers of Versican Plus BB Oral, the UK's first oral companion animal vaccine. Versican Plus BB Oral provides robust Bordetella protection with easy oral delivery. Speak to your Zoetis Account manager to learn more about Versican Plus BB Oral.

Whooping cough (or pertussis; in Finnish “hinkuyskä”) is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis and is responsible for an estimated 160 700 deaths each year worldwide. Despite extensive immunizations, pertussis is still one of the world's worst controlled vaccine preventable disease. Epidemics occurred in many industrial countries. Professor Qiushui He will explain in his lecture the reasons why pertussis is re-emerging and what actions we have taken in Europe in diagnosis, surveillance and prevention of this disease. Luennon tekstivastine: https://www.utu.fi/fi/yliopisto/akateemiset-juhlat/professoriluennot/joulukuu-2021/Qiushui-He

Múltiples agentes causales La tranqueobronquitis infecciosa canina, complejo respiratorio infeccioso canino o tos de las perreras, es un síndrome muy frecuente y contagioso en el que están involucrados un amplio número de patógenos bacterianos y víricos: Bacterias: Destaca B. bronchiseptica, es considerado uno de los principales agentes etiológicos de la enfermedad, que puede jugar un papel como patógeno primario o invasor secundario. Su adherencia a los cilios respiratorios y la posterior síntesis de exotoxinas inhibe la acción de los cilios y bloquea la fagocitosis celular. Esto favorece el efecto patógeno de otros agentes causales. Virus: El virus del parainfluenza canino y el adenovirus canino tipo 2, entre otros virus, se asocian frecuentemente a la enfermedad. ¿QUÉ SÍNTOMAS PUEDE PRODUCIR LA TOS DE LAS PERRERAS? Debido a los efectos de estos microorganismos en los tejidos del aparato respiratorio superior, su principal síntoma es una tos seca e intensa, que puede ser continua, y suele acompañarse de abundante mucosidad nasal, estornudos, dificultad respiratoria, fiebre, decaimiento y pérdida de apetito; además, en casos graves, los perros pueden desarrollar importantes neumonías. Aunque el riesgo de fallecer es bajo, si la enfermedad no se trata de forma correcta a tiempo, probablemente tu perro enfermo necesitará largos tratamientos con antibióticos, y fármacos para combatir la mucosidad y dificultad respiratoria. Por ello, dada la sintomatología y su alta contagiosidad, la mejor forma de controlar la enfermedad es mediante la prevención. ¿QUÉ SE PUEDE HACER PARA EVITAR LA ENFERMEDAD? Tu veterinario te ayudará a proteger a tu perro frente a Bordetella bronchiseptica y el virus del parainfluenza canino mediante la vacunación, que son dos de los principales agentes infecciosos involucrados en la tos de las perreras. Y recuerda, es importante proteger a los perros desde cachorros, que es cuando son más vulnerables a las enfermedades. Esperemos que os haya sido útil este podcast junto a este blog y cuidemos entre todo mejor de nuestras mascotas y nuestras familias.

Dr. James Fleckenstein, a professor of medicine and molecular microbiology at Washington University School of Medicine in St. Louis, and Sarah Gregory discuss three case reports of Bordetella hinzii infection in this podcast. Read the associated articles in Emerging Infectious Diseases.

Dr. James Fleckenstein, a professor of medicine and molecular microbiology at Washington University School of Medicine in St. Louis, and Sarah Gregory discuss three cases of Bordetella hinzii syndromes.

Rowan Sanderson sits down with Dr. Brendan Clarke to discuss the difference between kennel cough and whooping cough, or Bordetella and how to treat a dog who is experiencing mild coughing fits. Listen in as Brendan explains how to tell whether you need to take your dog to the vet or to let the cough pass after a few days with the help of natural remedies. In particular, he discusses how to offer your dog honey to soothe a sore throat and echinacea to support their immune system.

Tis the season to talk about Dr. Natalie Marks favorite topic, leptospirosis. She explains the bad news: This may be fatal to your dog and also is zoonotic, or at least potentially, which mean this bacterial infection can make people sick. The good news is that we can vaccinate our dogs against it. We also discuss pairing […]

Microbiologia médica de Murray. Lauria AM, Zabbo CP. Tos ferina [Actualizado el 7 de enero de 2021]. En: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 enero-. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK519008/ --- Send in a voice message: https://anchor.fm/las-poderosas-celulas-nk/message

Dr. Adriana Cabal Rosel, a public health microbiologist at the Austrian Agency for Health and Food Safety, and Sarah Gregory discuss the use of a new surveillance system to track increased cases of Bordetella pertussis in Austria.

In this VETgirl online veterinary continuing education podcast, we discuss different treatment protocols for canine Bordetella bronchiseptica (Bb), including the use of aerosolized antimicrobial therapy, specifically the aminoglycoside, gentamicin. In a study by Canonne et al, the authors wanted to evaluate the clinical response in dogs affected by Bb when administered 2 distinct protocols of aerosolized gentamicin.

Pertussis, also known as whooping cough and the 100 day cough, is caused by a bacterial infection. The usual pathogen is Bordetella pertussis, but can also be Bordetella parapertussis. Vaccinations worldwide have overall decreased mortality – prior to vaccination, pertussis was the leading cause of death from communicable disease among US children

Whooping cough, also called ‘the cough of 100 days’, is an acute and highly contagious disease of the upper respiratory tract caused by the bacterium Bordetella pertussis. It is transmitted via droplets in the air from coughing and sneezing. The main symptoms are severe bouts of coughing, often followed by vomiting. Before the introduction of a whooping cough vaccine in the 1950s, whooping cough was a major cause of infant death, with more than 120,000 infections annually in the UK. Vaccination was incredibly successful and resulted in a 99% fall in incidence. However, worldwide (mostly in developing countries), it still kills nearly 200,000 infants and adolescents annually. In this podcast, I explore why we're now seeing a re-emergence of whooping cough in the UK, particularly in older children and adults. (With thanks to our sponsor 'Curriculum Press' for providing content for this podcast)

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.14.296129v1?rss=1 Authors: Voegele, A., Sadi, M., O'Brien, D. P., Gehan, P., Raoux-Barbot, D., Davi, M., Hoss, S., Brule, S., Raynal, B., Weber, P., Mechaly, A., Haouz, A., Rodriguez, N., Vachette, P., Durand, D., Brier, S., Ladant, D., Chenal, A. Abstract: The molecular mechanisms and forces involved in the translocation of bacterial toxins into host cells have thus far remained elusive. The adenylate cyclase (CyaA) toxin from Bordetella pertussis displays a unique intoxication pathway in which its catalytic domain is directly translocated across target cell membranes. We have previously identified a translocation region in CyaA that contains a segment, P454 (residues 454-484), exhibiting membrane-active properties related to antimicrobial peptides. Herein, we show that this peptide is able to translocate across membranes and interact with calmodulin. Structural and biophysical analyses have revealed the key residues of P454 involved in membrane destabilization and calmodulin binding. Mutational analysis demonstrated that these residues play a crucial role in CyaA translocation into target cells. We have also shown that calmidazolium, a calmodulin inhibitor, efficiently blocks CyaA internalization. We propose that after CyaA binding to target cells, the P454 segment destabilizes the plasma membrane, translocates across the lipid bilayer and binds calmodulin. Trapping of the CyaA polypeptide chain by the CaM:P454 interaction in the cytosol may assist the entry of the N-terminal catalytic domain by converting the stochastic process of protein translocation into an efficient vectorial chain transfer into host cells. Copy rights belong to original authors. Visit the link for more info

Here in the 21st century, we have all grown accustomed to seeing that most common of all creatures. The most common of all dog breeds. The most popular of all companion animals – you guessed it - The social butterfly dog! Our clients dogs have very active social lives. In fact, US pet owners spent more than $6 billion on boarding and grooming services alone in 2017. On today’s show, Dr. Jen and Dr. Jason talk all about dogs and their very socially active lives and what veterinarians need to do to make sure that they stay safe and healthy. This show is brought to you by Nobivac® vaccines who want to encourage dog owners to pair up Bordetella and dog flu for the best protection for their pets. Learn more at dogflu.com EPISODE NOTES: In Other News… Dogs Need To Social Distance?

When you bring that soft, sweet-smelling little ball of a puppy into your home, you know right away that she depends on you for, well, everything. It’s up to you to give her all the care she needs every day. It can be a little intimidating — she needs the best puppy food, plenty of attention, gentle training, safe toys, puppy socialization, a comfortable home, and proper veterinary care. And that includes puppy shots throughout her first year. Which Vaccinations Do Puppies Need? Going to the vet repeatedly over several months for vaccinations, and then for boosters or titers throughout your dog’s life, may seem like an inconvenience, but the diseases that vaccinations will shield our pets from are dangerous, potentially deadly, and, thankfully, mostly preventable. We read about so many different vaccinations, for so many different illnesses, that it can sometimes be confusing to know which vaccinations puppies need and which ones are important but optional. Here is an overview of the diseases that vaccinations will help your pet to avoid. Bordetella Bronchiseptica This highly infectious bacterium causes severe fits of coughing, whooping, vomiting, and, in rare cases, seizures and death. It is the primary cause of kennel cough. There are injectable and nasal spray vaccines available. Canine Distemper A severe and contagious disease caused by a virus that attacks the respiratory, gastrointestinal (GI), and nervous systems of dogs, raccoons, skunks, and other animals, distemper spreads through airborne exposure (through sneezing or coughing) from an infected animal. The virus can also be transmitted by shared food and water bowls and equipment. It causes discharges from the eyes and nose, fever, coughing, vomiting, diarrhea, seizures, twitching, paralysis, and, often, death. This disease used to be known as “hard pad” because it causes the footpad to thicken and harden. There is no cure for distemper. Treatment consists of supportive care and efforts to prevent secondary infections, control symptoms of vomiting, seizures and more. If the animal survives the symptoms, it is hoped that the dog’s immune system will have a chance to fight it off. Infected dogs can shed the virus for months. Canine Hepatitis Infectious canine hepatitis is a highly contagious viral infection that affects the liver, kidneys, spleen, lungs, and the eyes of the affected dog. This disease of the liver is caused by a virus that is unrelated to the human form of hepatitis. Symptoms range from a slight fever and congestion of the mucous membranes to vomiting, jaundice, stomach enlargement, and pain around the liver. Many dogs can overcome the mild form of the disease, but the severe form can kill. There is no cure, but doctors can treat the symptoms. Canine Parainfluenza One of several viruses that can contribute to kennel cough. Corona Virus It is a virus that usually affects dogs’ gastrointestinal systems, though it can also cause respiratory infections. Signs include most GI symptoms, including loss of appetite, vomiting, and diarrhea. Doctors can keep a dog hydrated, warm, and comfortable, and help alleviate nausea, but no drug kills coronaviruses. Heartworm When your puppy is around 12-to-16 weeks, talk to your vet about starting her on a heartworm preventive. Though there is no vaccine for this condition, it is preventable with regular medication. The name is descriptive — these worms lodge in the right side of the heart and the pulmonary arteries (that send blood to the lungs), though they can travel through the rest of the body and sometimes invade the liver and kidneys. The worms can grow to 14 inches long and, if clumped together, block and injure organs. A new infection often causes no symptoms, though dogs in later stages of the disease may cough, become lethargic, lose their appetite or have difficulty breathing. Infected dogs may tire after mild exercise. Unlike most of the conditions listed here, which are passed by urine, feces, and other body fluids, heartworms are transmitted by mosquitoes. Therefore, diagnosis is made via a blood test and not a fecal exam. The FDA has more information about heartworm. Kennel Cough Also known as infectious tracheobronchitis, kennel cough results from inflammation of the upper airways. It can be caused by bacterial, viral, or other infections, such as Bordetella and canine parainfluenza, and often involves multiple infections simultaneously. Usually, the disease is mild, causing bouts of harsh, dry coughing; sometimes it’s severe enough to spur retching and gagging, along with a loss of appetite. In rare cases, it can be deadly. It is easily spread between dogs kept close together, which is why it passes quickly through kennels. Antibiotics are usually not necessary, except in severe, chronic cases. Cough suppressants can make a dog more comfortable. Leptospirosis Unlike most diseases on this list, Leptospirosis is caused by bacteria, and some dogs may show no symptoms at all. Leptospirosis can be found worldwide in soil and water. It is a zoonotic disease, meaning that it can be spread from animals to people. When symptoms do appear, they can include fever, vomiting, abdominal pain, diarrhea, loss of appetite, severe weakness and lethargy, stiffness, jaundice, muscle pain, infertility, kidney failure (with or without liver failure). Antibiotics are effective, and the sooner they are given, the better. Lyme Disease Unlike the famous “bull’s-eye” rash that people exposed to Lyme disease often spot, no such telltale symptom occurs in dogs. Lyme disease (or borreliosis) is an infectious, tick-borne disease caused by a type of bacteria called a spirochete. Transmitted via ticks, an infected dog often starts limping, his lymph nodes swell, his temperature rises, and he stops eating. The disease can affect his heart, kidney, and joints, among other things, or lead to neurological disorders if left untreated. If diagnosed quickly, a course of antibiotics is extremely helpful, though relapses can occur months or even years later. Parvovirus Parvo is a highly contagious virus that affects all dogs, but unvaccinated dogs and puppies less than four months of age are at the most risk to contract it. The virus attacks the gastrointestinal system and creates a loss of appetite, vomiting, fever, and often severe, bloody diarrhea. Extreme dehydration can come on rapidly and kill a dog within 48-to-72 hours, so prompt veterinary attention is crucial. There is no cure, so keeping the dog hydrated and controlling the secondary symptoms can keep him going until his immune system beats the illness. Rabies Rabies is a viral disease of mammals that invades the central nervous system, causing headache, anxiety, hallucinations, excessive drooling, fear of water, paralysis, and death. It is most often transmitted through the bite of a rabid animal. Treatment within hours of infection is essential, otherwise, death is highly likely. Most states require a rabies vaccination. Check with your vet about rabies vaccination laws in your area. Of course, your veterinarian should weigh in and can always provide more information and guidance if needed on necessary and optional vaccinations. Puppy Vaccination Schedule The first thing to know is that there is not just one puppy vaccination schedule for all dogs. Factors such as which part of the country you live in, and your dog’s individual risk factors will come into play. Some dogs do not need every vaccine. This decision is between you and your veterinarian. Always discuss puppy vaccinations at your regularly scheduled appointments. That said, here is a generally accepted guideline of the puppy vaccination schedule for the first year. Puppy’s Age Recommended Vaccinations Optional Vaccinations 6 — 8 weeks Distemper, parainfluenza Bordetella 10 — 12 weeks DHPP (vaccines for distemper, adenovirus [hepatitis], parainfluenza, and parvovirus) Coronavirus, Leptospirosis, Bordetella, Lyme disease 12 — 24 weeks Rabies none 14 — 16 weeks DHPP Coronavirus, Lyme disease, Leptospirosis 12 — 16 months Rabies, DHPP Coronavirus, Leptospirosis, Bordetella, Lyme disease Every 1 — 2 years DHPP Coronavirus, Leptospirosis, Bordetella, Lyme disease Every 1 — 3 years Rabies (as required by law) none Puppy Vaccinations Cost How much vaccinations for your puppy will cost depends on several factors. Where you live is one: Veterinarians in crowded and expensive urban areas will charge more than a rural vet in a small town. In other words, there are significant differences in price. But no matter what the range in costs, some vaccines, such as the “core vaccines,” and for rabies, are necessary. Vet Info has a helpful guide for the approximate cost of puppy vaccinations for her first year. The average cost will be around $75—100. These will include the core vaccines, which are administered in a series of three: at 6-, 12-, and 16 weeks old. The core vaccines include the DHLPP (distemper, hepatitis, leptospirosis, parvo, and parainfluenza). Your pup will also need a rabies vaccination, which is usually around $15—20. (Some clinics include the cost of the rabies vaccination.) Often animal shelters charge less for vaccines — approximately $20 — or are even free. If you acquired your dog from a shelter, he would most likely have been vaccinated, up until the age when you got him. The initial puppy vaccination costs during the first year are higher than during adulthood. Vaccinations After Puppyhood: Boosters and Titers There is a difference of opinion about having your adult dog vaccinated every year. Some vets believe too many vaccinations in adult dogs pose health risks. But others disagree, saying that yearly vaccinations will prevent dangerous diseases such as distemper. Many dog owners opt for titer tests before they administer annual vaccinations. Titer tests measure a dog’s immunity levels, and this can determine which, if any, vaccinations are necessary. Please note that a titer test is not an option when it comes to the rabies vaccine. These are required by law (see above). Your vet can tell you the schedule for your particular state. And it’s all worth it. For your effort and care your puppy will lavish you with lifelong love in return. This critical first year of her life is a fun and exciting time for both of you. As she grows physically, the wonderful bond between you will grow, too.      

This is a podcast for diligent, dedicated dog and cat parents on topics that have been in the news lately.Recently, the FDA issued a report citing 16 dog food brands linked to cases of dilated cardiomyopathy ( DCM), essentially a form of heart failure. Specifically, the FDA linked grain-free products and "exotic" foods to DCM. The proposed mechanism of action is that grain-free diets lead to a depletion of taurine, a non-essential amino acid made from cysteine and methionine in the liver, which then leads to cardiomyopathy. As one can imagine, the FDA's report caused massive panic amongst dog parents who worried that their dogs, if on a grain-free or exotic diet, may be at risk for DCM. In the second half of this podcast, Dr. Dodds discusses the FDA report, the data for and against the notion that grain-free diets cause DCM, benefits vs risks of a grain-free diet for dogs, and what dog parents can do if they are worried about their dog having DCM. Vaccines are always in the news. In the first half of this podcast, Dr. Dodds discusses her recommended vaccination protocol for dogs and cats, the concept of vaccinosis, dogs at the highest risk for vaccinosis, lifestyle vaccines ( Leptospirosis, Lyme Disease, Bordetella and Canine Flu) vs core vaccines, and why she recommends getting titer tests vs getting boosters. Dr. Jean Dodds received her doctorate of veterinary medicine in 1964 and has been a clinical research veterinarian and hematologist for over 5 decades. She was a grantee of the National Heart, Lung and Blood Institute and has authored over 150 peer-reviewed publications in top journals. She started HemoPet, the first national nonprofit blood bank for animals, in 1986. Some of the services HemoPet provides include: Providing canine blood components, adopting retired Greyhound blood donors as companions and the Hemolife diagnostic division which focuses on hematology ( the study of blood cells), blood banking, immunology, endocrinology, nutrition and holistic medicine. She invented NutriScan, a food sensitivity and intolerance diagnostic test for dogs, cats and horses and is also a Co-Trustee of the Rabies Challenge Fund, a nonprofit project for assessing the duration of immunity and safety of current rabies vaccines in animals. She's an active member of the American Holistic Veterinary Medical Association and the American Holistic Veterinary Medical Foundation. For information about this podcast, please contact Dr. Erin Stair through her website, Blooming Wellness. To read Erin's new comedic book on the wellness industry, click here: Yours in Wellness, Krystal Heeling.Follow Erin on Instagram here.

Impfen ist derzeit keine Pflicht - jeder darf selbst entscheiden! Link zum Blog-Beitrag: https://www.tierarzt-talk-time.com/impfungen-beim-hund Auf meiner Praxis Seite findest du auch noch weiter Infos: https://www.tier-homoeopathie.at/leistungen/impfungen Core-Impfungen: Staupe Parvovirose (Katzenseuche) Infektiöse Hepatitis (H.c.c.), Zoonosen: Leptospirose, Tollwut  Non core-Impfungen: Zwingerhusten (Virale Erreger, Bordetella bronchiseptica) Borreliose Babesiose Leishmaniose Was ist zu bedenken: Gesundheitsstatus Akut krank Chronisch krank Frühere Impfreaktionen Lebensumstände: Zwerghunde in der Stadt Ausstellungshunde Auslandsreisen  Unzuverlässige Hunde Einstellung des Besitzers/ Tierhalters Nichts ist ohne Risiko Frühere Erfahrungen mit anderen Tieren  Häufigkeit der Impfungen: Über 16 Wochen genügt eine Impfung 3 Jahre ist minimale Schutzzeit (außer bei Leptospirose) Zu frühe Impfung (Titer noch ausreichend) kann dazu führen, dass der Impftiter sogar sinkt. Auffrischungsimpfungen: Nur Leptospirose jährlich Jährliche Kontrolle beim Tierarzt trotzdem wichtig!  Nebenwirkungen: Statistisch wenige – aber werden alle erfasst? Beispiel Fibrosarkom Katze: Nach Monaten bis Jahren – andere chronische Beschwerden? Meldepflicht für Nebenwirkungen  Beispiel Leptospirose in Kuba – Homöopathie hat massive positive Auswirkungen auf Neuerkrankungen und Sterbefälle: https://www.ncbi.nlm.nih.gov/pubmed/20674839   Die Gesundheit von Hund und Katze kannst du selbst beeinflussen. Du selbst! Im Tierarzt-Podcast von Ines Kitzweger lernst du, was du tun kannst, um dein Tier lange fit und aktiv zu halten. Thematisch geht es in jeder Folge um ein anderes Thema mit Hintergrundwissen sowie Tipps und Tricks, die du selbst anwenden kannst. Egal ob es um Allergien, chronische Darm-Erkrankungen (IBD), Schilddrüsen-Erkrankungen, Impfungen, Verhaltensauffälligkeiten oder andere Themen geht: Alternativmedizin kann viel mehr, als du vielleicht bisher weißt! Mach dein Tier gesund und begleite es durch ein langes glückliches Leben!

In this episode we discuss questions every dog owner should ask their veterinarian. To get the full article visit: https://www.bostonterriersociety.com/questions-to-ask-veterinarian/ Having a dog is a lot of responsibility. It is not enough just to love them unconditionally, it is absolutely necessary to know a thing or two about how to keep them healthy. I'm not expecting every pet owner to take medical classes. I am saying, find a veterinarian that you and your dog trust, then dive into their vast knowledge pool.  If you don't know where to start, here are some of the top questions that every dog owner needs to ask their veterinarian. 1.  What Vaccinations Does My Dog Need and When? Vaccinations are one of the best ways to keep your pup healthy. They help prevent your dog from contracting illnesses or at least decrease the severity of these illnesses if they do get them. The vaccinations your dog needs varies depending on their lifestyle and the area in which you live.   Every dog, regardless of lifestyle, age, or location, should receive the core vaccines for rabies, parvovirus, distemper, and canine hepatitis. Additional vaccines for leptospirosis, influenza, Bordetella, Lyme disease and others should be given if your veterinarian deems necessary. How Old Should Your Dog Be? Pups should be vaccinated, starting at six to eight weeks of age. Depending on the specific vaccine, boosters should be given every three to four weeks for a total of at least three.   Rabies vaccine can be given starting at 12 weeks of age. After that, some vaccinations may be given yearly or every three years or longer. This is why it is vital to discuss vaccinations with your vet to determine your dog's best schedule. 2.  How Often Should I Bring My Dog to the Vet? Again, this is going to depend on your veterinarian. Most vets like to see you at least once a year, even if no vaccinations are required at that time. This is just to perform a general wellness exam checking for internal and external issues.  Vets also like to monitor oral health and may recommend blood work to check for hidden health issues. Don't be surprised if your vet asks that you come in every six months, especially as your dog ages. This just helps them to keep better track of your pup's health and to catch any problems before they become big. Of course, you're welcome to visit as often as you see fit! 3. What Should I Feed My Dog? All dog foods are not created equal. In fact, there are vast differences out there between dog foods, and it may seem like an impossible task to pick which one is right for your dog. Obviously, if your pup has a condition in which diet is a factor, such as allergies or irritable bowel syndrome. Your vet is your number one source for dietary recommendations. However, you should also utilize your veterinarian's knowledge to help you choose a dog food for a pup without special nutritional needs. Your veterinarian will help you choose a product that provides proper nutrition for your best friend. As well as find a dog food one that tastes good and is priced within your range. Don't be afraid to do a little research on your own and then ask your vet's opinion about certain dog food brands to help narrow down your search. To get the full article visit: https://www.bostonterriersociety.com/questions-to-ask-veterinarian/ --- Send in a voice message: https://anchor.fm/bostonterriersociety/message Support this podcast: https://anchor.fm/bostonterriersociety/support

Kennel cough, or Bordetella, is a common highly contagious upper respiratory condition in dogs. Dr. Becker discusses how dogs get it, symptoms and how to treat it.

Kennel cough in dogs Kennel cough is a condition that affects the upper respiratory tract of dogs and is characterized by the inflammation of the trachea and bronchi. While kennel cough may sound like a horrific condition, it’s not actually as terrible as most dog owners assume. However, the effects of the condition can vary depending on each individual dog. For this reason, you may want to avoid your dog catching the illness if possible. To do this, you need to understand where the name comes from. Why is it called kennel cough? This condition is referred to as a kennel cough because, perhaps, unsurprisingly it is most commonly found and caught in kennels or anywhere that there are a lot of dogs in close proximity to one another. Kennels or shelters are the obvious risk zone, but training facilities and dog parks can be another place where dogs are likely to contract this illness. Ultimately kennel cough in dogs is very much like the typical human cold. It’s very common and will spread from dog to dog. Kennel cough causes Kennel cough does not have one individual cause. There are often multiple infectious agents that are working at the same time to infect your dog. Which is why it is also referred to as Canine Infectious Respiratory Disease (CIRD) or Infectious Tracheobronchitis. Viral pathogens include canine distemper (CDV), canine parainfluenza (CPIV), canine adenovirus type 2 (CAV-2), canine influenza (CIV), canine herpesvirus (CHV), canine respiratory coronavirus (CRCoV), pantropic canine coronavirus, canine reovirus, and canine pneumovirus (CnPnV). Bacterial pathogens include Bordetella bronchiseptica, Mycoplasma spp., and Streptococcus equi subsp. zooepidemicus. One of the most common causes is a bacteria known as Bordetella bronchiseptica. Due to this cause kennel cough may also be referred to as Bordetella. However, this bacteria may work with a virus such as canine distemper or canine parainfluenza. Both are problematic for your pet as they weaken the animal’s immune system and affect both the dog’s voice box and windpipe. Dogs can contract a kennel cough in a variety of different ways. The most common way is to catch it from the air as it is spread by another dog. A dog with this infection may sneeze, bark or cough. Any one of these things can flood the air with thousands of organisms.. A dog may also get infected by using an item such as a toy or food dish that another dog with the infection has used. You should also know that bacteria can remain alive on a food bowl for up to forty-eight hours. This is another reason why you should be wary of kennels, particularly if there are signs that dogs at that kennel are infected. The final way this disease can spread is through animal interactions. Whether your dog plays, sniffs or licks another dog, if it has the infection, it will almost certainly pass it on. So, while letting your dog play with another dog may seem fun you do have to be careful. Signs of kennel cough One of the challenges of keeping a dog with a kennel cough away from other dogs is that it’s not always possible to tell that they have it. A dog can carry kennel cough and show no symptoms at all yet still pass on the infectious organisms to other dogs. As such, a dog might seem safe for your pet to interact with and still be carrying kennel cough. Not much you can do in that case. Other dogs will present more symptoms. The most common symptom is a dry, hacking cough. This may be followed by gagging or retching.  It will be irritating for your dog and may even hurt her throat. It can sound far worse than it is so try not to panic if your dog does start to show this symptom. In most cases, this cough is completely harmless and will go away within a couple of weeks. Still you should have your dog checked out by your veterinarian as there are other causes of coughing that are more serious.  Make sure you call or otherwise notify them you are coming in so they can take precautions to prevent infection of other dogs in the hospital. On rare occasions, this condition can lead to further complications. Some dogs may develop a fever and seem lethargic. However, you still don’t have to worry too much about the impact of this condition. With treatment, a dog will still recover. In extremely rare cases, this condition can lead to something far more sinister which is pneumonia. Pneumonia may develop due to your dog’s weakened immune system. However, it is important to understand that this is incredibly rare. Even so, if you think your dog’s condition is getting worse, you should always get them checked out by the vet. Treatment for kennel cough Many cases of a kennel cough may not require any  treatment. Although rest and isolation from other dogs will likely be recommended.  In two weeks, a dog will usually fully recover and be back to its old self. If the condition is more severe, they may be provided antibiotics to help fight the infection and/or a cough suppressant by a vet. In some cases tests (such as chest x-rays) and more aggressive treatment may be necessary. Pet medical insurance typically applies to these tests. The condition is likely to be more severe and potentially dangerous in older dogs, young puppies and any dog with a severely weakened immune system. If your dog fits into any of these categories, you should go and see your vet as soon as possible. They will determine whether further treatment is necessary. With treatment, most dogs will recover fully in roughly two weeks. On occasion, however, some dogs may have a longer course of 2-6 weeks.. Preventing kennel cough As with other conditions, the best way to approach a kennel cough is to prevent it from developing. There are several ways to do this including checking out the dogs your pooch is playing with. Ask the owner whether they are up to date on their vaccinations. There is a vaccination for Bordetella, and if you visit your vet, they can provide you information on this. If you are using kennels or a doggy daycare check them out thoroughly, ensuring they are clean and sanitized. Kennel cough is just one of the nasty illnesses your dog can pick up at kennels which aren’t being properly cleaned and maintained.

Dr. Jeff Miller has been studying Bordetella pertussis, the bacterium that causes whooping cough in humans, for over three decades, and he keeps uncovering novel aspects of the pathogenesis of this organism. B. pertussis still causes outbreaks of human disease, and Dr. Miller has unraveled in amazing detail the signal transduction system that leads to whooping cough. Dr. Miller is a professor at the University of California Los Angeles, the director of the California NanoSystems Institute, past-president of the American Society for Microbiology, and a member of the National Academy of Sciences. Dr. Miller talks about diversity generating retroelements in Bordetella bacteriophages and how these allow tropism switching, why we still need to study Bordetella for vaccine research, how science communication is important to combat the anti-vaxx movement, how the NanoSystems Institute aims to push technologies toward translational applications, and how being ASM president (twice!) was a labor of love. microTalk recorded this discussion with Dr. Miller during a live podcast at the American Society for Microbiology Microbe 2018 meeting in Atlanta, Georgia, and it includes questions from the audience. The microCase for listeners to solve is about John Deer, who comes down with a life-threatening infection while waterskiing Participants: Karl Klose, Ph.D. (UTSA) Jeff Miller, Ph.D. (University of California Los Angeles) Janakiram Seshu, Ph.D. (UTSA) Jesus Romo, Ph.D. (UTSA)

Grandmother is portrayed as the big bad wolf in a whooping cough vaccine PSA. A killer infectious disease called Pertussis is a bacterial infection that causes whooping cough. Vaccines had brought the numbers of cases down dramatically, but now they’re on the rise again and Texas Biomed animals and scientists are involved in the search for something better to treat this health problem that kills more than a hundred thousand infants a year. Pertussis has seen an alarming resurgence in the last decade. That’s surprising, given that a vaccine for this infectious disease has existed since the 1930s. The original vaccine, made with whole-cell killed Bordetella pertussis bacteria, was very effective but associated with some adverse events. A newer acellular pertussis vaccine with fewer adverse events was approved by the FDA in 1997. Recent epidemiological studies have found, however, that the immunity conferred by the new vaccine wears out during adolescence. That’s a problem, because although whooping cough isn’t fatal to adults, adults whose immunity has waned can carry and transmit the disease to infants, for whom it is frequently fatal. Infants typically receive antibodies from their mothers, but if the mother is not immune to pertussis, she cannot pass on immunity to the infant — thus putting the infant at risk of infection. And although the pertussis bacteria can be killed with antibiotics, the toxins released by the bacteria have done irreparable damage to the lung by the time the infant develops whooping cough. A current but imperfect strategy to protect infants is “cocooning” — that is, vaccinating anyone who might come into contact with the infant, including parents, siblings, grandparents, babysitters, and the like. Nevertheless, the loss of pertussis immunity in the population as a whole, combined with the fact that many parents now choose not to vaccinate their children, has caused pertussis to become one of the largest preventable causes of death due to infectious disease worldwide in infants. To address this problem, researchers have been working to develop an improved pertussis vaccine. Some of these new strategies are now ready for pre-clinical testing, which is required by the FDA before moving forward with human clinical trials. Baboons at SNPRC are models for pertussis vaccine research. “It turns out the baboon is the perfect model for pre-clinical testing, because it is the only animal that mimics humans in that infant baboons develop a persistent cough when exposed to pertussis,” explained Robert Lanford, Ph.D., Director of the Southwest Primate Research Center (SNPRC). SNPRC is one of seven NIH-funded primate research centers across the country, and the only one that houses a colony of baboons. It is thus in a unique position to advance pertussis vaccine research at this critical stage. Working with the FDA and pharmaceutical companies, Lanford’s team is using the baboon model for testing new approaches to improving the acellular vaccine. Some of these new approaches use novel adjuvants (compounds designed to enhance immunity to vaccines) that can be used in combination with the existing acellular pertussis vaccine. Photo Courtesy healthcautions.com “The fastest way to get a better vaccine is not to make a new vaccine, because it takes decades to get a new vaccine approved; it is to enhance one that we already know is safe,” Dr. Lanford said. Of course, this isn’t guaranteed to work, so some research groups are taking different approaches and attempting to develop a new vaccine from scratch, he added. The goal is to produce data that will be used by the FDA to evaluate the potential effectiveness of the new vaccine and to decide if it can move forward to testing in human clinical trials, explained Dr. Lanford. It is usually a multi-year process. “Drugs that look most promising at first can run into safety problems,” Dr. Lanford explained. “It’s hard to predict which one will get through...

SoulPup Episode 1: Tips to Protect Your Dog’s Health When you bring home a dog, veterinary care is one of the most important components to raising a happy, healthy dog. Avoid sticker shock with veterinary visits with tips from Dr. Annie Price of Ormewood Animal Hospital in metro Atlanta. BEFORE you schedule a veterinary appointment.  Whether it’s a puppy or an older rescue dog, schedule that initial vet visit within the first week or two of bringing your dog home. Bring any vaccination records or other info regarding the dog’s history. Also, it pays to take note of any behavioral or health issues you may notice. Share any questions or concerns during your vet visit. New to the area or in need of a veterinarian? Ask friends for referrals. Dr. Price also suggests checking with a local referral service. For a list of accredited hospitals across the country, visit the American Animal Hospital Association. To find a board-certified veterinary expert in your are, visit Vetspecialists.com and enter your ZIP code. Prepare to vaccinate your dog. While the rabies vaccination is required for dogs, your dog’s lifestyle may mean that some other shots are not necessary. For example, a Yorkie that doesn’t socialize with any other dogs and only potties on a pee pad can probably skip the Bordetella vaccine, which is typically required for dogs that attend dog parks, boarding facilities or doggie daycare centers. Canine influenza is another vaccine to consider if your dog frequently socializes with four-legged friends. Talk to your vet about your dog’s risk factor. As for the rabies shot, it’s available in a three-year dosage. Puppy vaccinations are administered from six to about 17 weeks of age so discuss vaccinations that may already have been administered and prepare to protect your pup,  particularly if you purchased from a breeder. There are benefits to spaying/neutering a dog. If your dog has not been spayed or neutered, expect the vet to make this suggestion. (For those who are unaware, spaying means removing a female dog’s ovaries and uterus. Neutering removes a dog’s testicles and cuts off blood supply to the vas deferens. Both procedures prevent dogs from producing puppies.) Spaying a dog before she reaches her first heat also can reduce her chances of developing breast cancer.  Dr. Price notes that, with neutering, dogs are less likely to mark areas of the house, and 90 percent of dogs hit by cars are intact male dogs (probably in search of a girlfriend). Protect those pearly whites. Dental cleaning sessions at the vet’s office can lead to the biggest “sticker shock” among dog owners. Dr. Price points out some of what goes into an actual cleaning for dogs or cats: The vet is cleaning involves polishing each tooth and cleaning under the gum line. This thorough cleaning can generate a lot of saliva and bacteria. Needless to say, scaling a pet’s teeth is not a pleasant experience and requires the animal to be fully anesthetized. Dr. Price says anesthesia is typically the biggest chunk of your bill. Before anesthetizing, most vets also will run blood tests to assess whether your pet is healthy enough to handle this procedure. During dental cleanings, Dr. Price says vets also monitor things like cardiac functions and oxygen levels. Regular dental hygiene at home is one of the best ways to reduce extensive veterinary procedures. Dr. Price advocates regularly brushing your dog’s teeth. Start as early as possible to get them used to having their mouths handled. Also, do not use human toothpaste. It can be toxic to dogs. Instead, visit your local pet store for a dog version. She also recommends avoiding hard chew such as deer antlers. She has had to conduct root canals and repair several cracked teeth due to dogs chewing tough items. Instead, opt for rubbery style chews. Invest in health insurance. The best way to cut costs at the veterinary clinic — and avoid stress if there is an emergency — is ...

Author: Julian Orenstein, M.D. Educational Pearls Colorado has a high population of unvaccinated children, and is at increased risk for pertussis outbreaks. The causative organism is Bordetella pertussis. It causes  causes respiratory epithelial necrosis leading to congestion of the bronchioles, leading to cough. The cough is unique - it is usually a series of expiratory coughs followed by one deep inspiration The clinical presentation is divided into 3 phases: Catarrhal: cough and congestion with low-grade fever and coryza. Whooping: characteristic cough. Resolution: recovery with persistent cough. Infants may not get this presentation, but may get apnea and nonspecific cough.   Tongue depressor can be used to elicit cough for diagnosis. References: Tozzi AE, Pastore Celentano L, Ciofi degli Atti ML, Salmaso S. Diagnosis and management of pertussis. CMAJ : Canadian Medical Association Journal. 2005;172(4):509-515. doi:10.1503/cmaj.1040766.

Whooping cough, caused by the bacterium Bordetella pertussis, is an extremely dangerous and potentially fatal disease for infants. We rarely see this disease anymore because everyone is routinely vaccinated against it with the DPT childhood vaccine. But there has lately been a resurgence in whooping cough cases, caused primarily by a reformulation of the vaccine to make it safer, which unfortunately also made it less protective against this disease. Dr. Rajendar Deora is an Associate Professor of Microbiology and Immunology at Wake Forest University. Dr. Deora’s research involves improving the whooping cough vaccine. Dr. Deora is studying how to improve this vaccine back to pre-reformulation levels of protection, without reducing its safety. Dr. Deora discusses vaccines, whooping cough, and his scientific career choice. Dr. Deora reminds everyone that “Vaccines Work!” Discussants (in alphabetical order): Dr. Neal Guentzel (Professor and Parliamentarian of STCEID, UTSA) Dr. Karl Klose (Professor and Director of STCEID, UTSA) Dr. Janakiram Seshu (Associate professor, STCEID, UTSA) microTalk is supported, in part, by the American Society for Microbiology. Visit asm.org to discover more microbiology resources and content.  

Im Rahmen der vorliegenden Arbeit wurde das Vorkommen von Bakterien im unteren Respirationstrakt von Hunden mit Atemwegserkrankungen und deren Resistenzverhalten gegenüber klinisch relevanten Antibiotika untersucht. Hierfür wurden die Ergebnisse der bakteriologischen Untersuchungen und Resistenztests von 502 Proben von 493 Hunden retrospektiv ausgewertet, die im Zeitraum von 1989 bis 2011 an der Medizinischen Kleintierklinik der Ludwig-Maximilians-Universität München mit respiratorischen Symptomen vorgestellt wurden. Aerobe Bakterien wurden aus 65 % der Proben isoliert, wobei in 47 % der positiven Kulturen mehrere Isolate nachgewiesen wurden. Grampositive Bakterien wurden aus 52 % und gramnegative Bakterien aus 77 % der Proben mit bakteriellem Wachstum kultiviert. Die häufigsten Isolate umfassten Spezies der Gattungen Streptococcus (31 %), Staphylococcus (19 %), Pasteurella (16 %) und Pseudomonas (14 %). Weiterhin konnten Enterobakterien in 30 % der positiven Proben nachgewiesen werden, bei denen es sich in der Hälfte der Fälle um Escherichia coli (15 %) handelte. Bordetella bronchiseptica als primär pathogenes Bakterium wurde in 8 % der positiven Fälle vergleichsweise selten isoliert. Im zweiten Teil der Arbeit wurde anhand der Ergebnisse des Agardiffusionstests die in-vitro-Sensibilität der häufigsten bakteriellen Isolate gegenüber den antibiotischen Wirkstoffen Enrofloxacin, Gentamicin, Cefalexin/Cefalotin, Amoxicillin-Clavulansäure, Sulfonamid/Trimethoprim, Cefotaxim, Doxycyclin und Ampicillin ausgewertet. Enrofloxacin zeigte die höchste Gesamtwirksamkeit aller getesteten antibiotischen Wirkstoffe gegenüber 86 % aller Keime, darunter 87 % der gramnegativen Isolate. Hochwirksam gegenüber grampositiven Bakterien erwiesen sich Amoxicillin-Clavulansäure (92 %) und Cephalosporine der ersten Generation (86 %), wobei 40 % der gramnegativen Isolate resistent gegenüber diesen Wirkstoffen waren. Ausgedehnte Resistenzen zeigten sich vor allem unter gramnegativen Spezies gegenüber Beta-Laktam-Antibiotika, potenzierten Sulfonamiden und Doxycyclin. Sehr hohe Resistenzraten wurden für Escherichia coli und Pseudomonas spp. nachgewiesen. Lediglich Enrofloxacin und Gentamicin wiesen eine Wirksamkeit gegenüber 70 bis 73 % dieser Isolate auf. Am empfänglichsten zeigten sich Pasteurella spp. mit weniger als 15 % Resistenzen gegenüber den meisten Antibiotika. Eine günstige Resistenzlage konnte auch für Bordetella bronchiseptica nachgewiesen werden. Hier lagen über 90 % sensible Isolate gegenüber Enrofloxacin, Gentamicin, Amoxicillin-Clavulansäure und Doxycyclin vor. Im Verlauf des Studienzeitraums konnte eine signifikante Abnahme der in-vitro-Wirksamkeit von Enrofloxacin gezeigt werden. Insbesondere für Escherichia coli konnte in der zweiten Hälfte des Untersuchungszeitraums ein signifikanter Anstieg des Anteils Enrofloxacin-resistenter Isolate nachgewiesen werden. Die Ergebnisse der vorliegenden Untersuchung unterstreichen aufgrund des nicht exakt vorhersehbaren Resistenzverhaltens der isolierten Bakterien die Notwendigkeit zur routinemäßigen Durchführung von bakteriologischen Untersuchungen und antibiotischen Resistenztests bei Hunden mit bakteriellen Atemwegsinfektionen. Anhand der erhobenen Daten kann Enrofloxacin zur empirischen antibiotischen Behandlung oder zur Initialen Therapie bis zum Vorliegen der Ergebnisse aus Erregerkultivierung und Resistenztests bei Infektionen mit gramnegativen oder unbekannten Erregern eingesetzt werden, während Amoxicillin-Clavulansäure zur Behandlung von Infektionen mit grampositiven Bakterien geeignet erscheint.

In this episode, we discuss Bordetella pertussis (whooping cough) with Dr. Michael Fennewald.

Vincent, Elio, Michael, and Michele discuss evidence that the acellular pertussis vaccine fails to prevent infection and transmission in nonhuman primates, and the use of bacterial cytological profiling to identify pathways targeted by antibiotics.

Sat, 20 Jul 2013 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/16089/ https://edoc.ub.uni-muenchen.de/16089/1/Kurz_Susanne.pdf Kurz, Susanne ddc:590, d

In a number of countries, whole cell pertussis vaccines (wcP) were replaced by acellular vaccines (aP) due to an improved reactogenicity profile. Pertussis immunization leads to specific antibody production with the help of CD4(+) T cells. In earlier studies in infants and young children, wcP vaccines selectively induced a Th1 dominated immune response, whereas aP vaccines led to a Th2 biased response. To obtain data on Th1 or Th2 dominance of the immune response in adolescents receiving an aP booster immunization after a wcP or aP primary immunization, we analyzed the concentration of Th1 (IL-2, TNF-α, INF-γ) and Th2 (IL-4, IL-5, IL-10) cytokines in supernatants of lymphocyte cultures specifically stimulated with pertussis antigens. We also investigated the presence of cytotoxic T cell responses against the facultative intracellular bacterium Bordetella pertussis by quantifying pertussis-specific CD8(+) T cell activation following the aP booster immunization. Here we show that the adolescent aP booster vaccination predominantly leads to a Th1 immune response based on IFNgamma secretion upon stimulation with pertussis antigen, irrespective of a prior whole cell or acellular primary vaccination. The vaccination also induces an increase in peripheral CD8(+)CD69(+) activated pertussis-specific memory T cells four weeks after vaccination. The Th1 bias of this immune response could play a role for the decreased local reactogenicity of this adolescent aP booster immunization when compared to the preceding childhood acellular pertussis booster. Pertussis-specific CD8(+) memory T cells may contribute to protection against clinical pertussis.

Ziel dieser Arbeit war es, die Prävalenz des felinen Herpesvirus-1 (FHV-1), des felinen Calicivirus (FCV), von Chlamydophila felis (C. felis) und von Bordetella bronchiseptica (B. bronchiseptica) in Mehrkatzenhaushalten (>= 5 Katzen) zu bestimmen. Es sollten Faktoren untersucht werden, die Einfluss auf die Prävalenz der Erreger haben. Zudem wurden Mehrkatzenhaushalte in denen Katzenschnupfen auftrat mit „gesunden“ Beständen verglichen und die Faktoren ermittelt, in denen sich die Bestände unterschieden. Der Nachweis von FHV-1, FCV und C. felis erfolgte mittels multiplex real-time Polymerase-Kettenreaktion (PCR). Zur Ermittlung der B.-bronchispetica-Prävalenz wurde ein Antikörpernachweis mittels enzyme-linked immunosorbent assay (ELISA) durchgeführt. Die Prävalenz in Beständen mit respiratorischen Problemen lag für FHV-1 bei 18,3 %, für FCV bei 57,6 % und für C. felis bei 8,2 %. In Beständen ohne respiratorische Probleme lag die Prävalenz für FHV-1 bei 11,6 %, für FCV bei 49,3 % und für C. felis bei 2,9 %. Keiner der drei Erreger trat signifikant häufiger in Beständen auf, in denen Katzenschnupfen vorkam. Die Antikörperprävalenz von B. bronchiseptica war in Beständen mit und ohne respiratorische Probleme ähnlich hoch (39,0 % bzw. 44,4 %). Die Einflussfaktoren wurden mittels multivariabler logistischer Regression untersucht. Faktoren, die einen signifikanten Einfluss auf den Nachweis des FHV-1 hatten, waren die Hygiene im Bestand sowie der Kontakt mit Hunden. Einen statistisch signifikanten Einfluss auf die FCV-Prävalenz hatten der Hygienestatus und die Anzahl der Katzen im Bestand. Auf die C.-felis-Prävalenz hatten die Hygiene und die Rasse der Katzen einen signifikanten Einfluss. Die B.-bronchiseptica-Antikörperprävalenz wurde vom Alter der Katzen und dem Bestandstyp signifikant beeinflusst. Beim Vergleich der Kontroll- und der Fallgruppe unterschieden sich nur der Anteil an männlichen Katzen und die Prävalenz von C. felis im Bestand signifikant. Zusammenfassend ist zu sagen, dass die Erreger des Katzenschnupfens, einschließlich B. bronchiseptica, trotz Impfprophylaxe weit verbreitetet sind. Von allen untersuchten Einflussfaktoren hat der Hygienestatus den größten Einfluss auf die Erregerprävalenz.