Podcasts about Atomic

On episode 96, Charles briefly praises a tiki bar in Grand Rapids, MI, and then talks to Shawnna Morris about her fascinating new book, The Cambridge Spy Ring: The Treachery of the Five Who Got Away. Among the topics they discussed were: Who were the Cambridge Spies? Why were they susceptible to recruitment? How did they get away with it? Why were none of them prosecuted or executed? Why does Shawnna find the Cold War so interesting?The dial-up tone in the introduction was recorded by lintphishx and is used under a CC 3.0 License. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

My guest this week is Rose Tipitino and Nick Leibee they are the owners of Atomic Drinkware- a stylish hand-painted retro glassware for modern life.I discussed with Rose and Nick about their journey of coming up with the idea to start Atomic Drinkware and how Nick had to learn how to print on glass and creating a press for it.  We discussed about their creative process and how they figure out releases.I also asked them about markets and advice for starting somethingLunch with Biggie is a podcast about small business and creatives sharing their stories and inspiring you to pursue your passion, with some sandwich talk on the side. Created, edited, and produced in Orlando, FL by Biggie- the owner of the sandwich-themed clothing brand- ⁠⁠Deli Fresh Threads⁠⁠. Atomic Drinkware Social:Atomic Drinkware Instagram: https://www.instagram.com/atomicdrinkware/Atomic Drinkware website- https://atomicdrinkware.com/Biggie's Social: ⁠⁠Deli Fresh Thread's Instagram⁠⁠- ⁠⁠https://www.instagram.com/delifreshthreads/⁠⁠ ⁠⁠Podcast's Instagram⁠⁠- ⁠⁠https://www.instagram.com/lunchwithbiggie/⁠⁠ ⁠⁠Podcast's Facebook Group⁠⁠- ⁠⁠https://www.facebook.com/groups/lunchwithbiggie⁠⁠ ⁠⁠Podcast's Twitter-⁠⁠ ⁠⁠https://twitter.com/LunchwithBiggie⁠⁠ ⁠⁠Deli Fresh Threads⁠⁠- ⁠⁠ ⁠https://DeliFreshThreads.com

Dopamine Method: 3 Steps to Find Your Passion (Science-Backed) October 27, 2025 | Episode 5211 Host: Scott Smith Episode Description Still collecting productivity frameworks that don't actually work? Smart goals. Atomic habits. All those little tactics sitting in your notebook while you're still off track. Here's the thing. They're too tactical. You need something that's wired into how your brain actually works. Three simple steps that change how you feel about your world starting today. Not next month. Today. Scott breaks down the science-backed approach that makes motivation stick. No frameworks to memorize. Just three strategic shifts that light you up from the inside. And what he discovered about your anticipation engine might surprise you. Featured Story Ever notice how excited you got about Christmas as a kid? Scott did too. Then he became an adult. Boring. Just work. One day he said screw that. Started putting concerts on the calendar. Ski trips. Anything that got him genuinely excited. And his whole life shifted. He realized something most people miss. When you schedule experiences that fire you up, your mood changes. Your motivation increases. You can handle anything at the office when you've got something coming up this weekend. Most people lacking motivation are just lacking hope. That puts them in doubt and fear. The trick? You need to know you're growing toward something. Important Points Why looking at the past to solve present problems keeps you stuck in the same patterns you're trying to escape. The anticipation engine discovery that makes kids excited about holidays works just as powerfully for adults who remember to use it. How connecting with 5-10 truly like-minded people creates more momentum than 5,000 Facebook friends ever will. Exploring future possibilities lights up your brain differently than trying to fix your current situation. Memorable Quotes "The present doesn't stick around. The only thing that guides you is the future." "If you're not exploring and looking forward, most people look at the past. That's not going to work for you." "We were not designed to do things alone, but make no mistake, we're also not designed to do things with 10,000 people." "Two or more people actively engaged in the pursuit of a definite purpose with a positive mental attitude constitute an unbeatable force." Scott's Three-Step Approach 1. Explore future possibilities instead of past solutions. Stop asking what worked 20 years ago and start asking where your interest guides you next. 2. Fire up your anticipation engine by scheduling one experience that genuinely excites you. Concert tickets. Weekend trip. New dress. Anything that makes you eager. 3. Connect with like-minded people in smaller groups of 5-10 who actually vibe with you naturally. No forcing it. No proving how smart you are. Chapters 00:00 Why Your Goal-Setting Frameworks Keep Failing 00:50 The Daily Boost Moves to YouTube (Big Announcement) 02:39 Stop Collecting Ideas That Don't Work 03:37 Step One: Explore Future Possibilities 05:27 The Anticipation Engine That Changes Everything 07:13 Step Three: Connect With Like-Minded People 09:24 What Messes People Up (It's Always One of These Three) 10:11 Tomorrow's Show: One Project at a Time Connect With Me Search for The Daily Boost on Apple Podcasts and Spotify. Email: support@motivationtomove.com Main Website: https://motivationtomove.com YouTube: https://youtube.com/dailyboostpodcast Facebook Page: https://facebook.com/motivationtomove Facebook Group: https://dailyboostpodcast.com/facebook Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Crazy Wisdom, host Stewart Alsop talks with Richard Easton, co-author of GPS Declassified: From Smart Bombs to Smartphones, about the remarkable history behind the Global Positioning System and its ripple effects on technology, secrecy, and innovation. They trace the story from Roger Easton's early work on time navigation and atomic clocks to the 1973 approval of the GPS program, the Cold War's influence on satellite development, and how civilian and military interests shaped its evolution. The conversation also explores selective availability, the Gulf War, and how GPS paved the way for modern mapping tools like Google Maps and Waze, as well as broader questions about information, transparency, and the future of scientific innovation. Learn more about Richard Easton's work and explore early GPS documents at gpsdeclassified.com, or pick up his book GPS Declassified: From Smart Bombs to Smartphones.Check out this GPT we trained on the conversationTimestamps00:00 – Stewart Alsop introduces Richard Easton, who explains the origins of GPS, its 12-hour satellite orbits, and his father Roger Easton's early time navigation work.05:00 – Discussion on atomic clocks, the hydrogen maser, and how technological skepticism drove innovation toward the modern GPS system.10:00 – Miniaturization of receivers, the rise of smartphones as GPS devices, and early mapping tools like Google Maps and Waze.15:00 – The Apollo missions' computer systems and precision landings lead back to GPS development and the 1973 approval of the joint program office.20:00 – The Gulf War's use of GPS, selective availability, and how civilian receivers became vital for soldiers and surveyors.25:00 – Secrecy in satellite programs, from GRAB and POPPY to Eisenhower's caution after the U-2 incident, and the link between intelligence and innovation.30:00 – The myth of the Korean airliner sparking civilian GPS, Reagan's policy, and the importance of declassified documents.35:00 – Cold War espionage stories like Gordievsky's defection, the rise of surveillance, and early countermeasures to GPS jamming.40:00 – Selective availability ends in 2000, sparking geocaching and civilian boom, with GPS enabling agriculture and transport.45:00 – Conversation shifts to AI, deepfakes, and the reliability of digital history.50:00 – Reflections on big science, decentralization, and innovation funding from John Foster to SpaceX and Starlink.55:00 – Universities' bureaucratic bloat, the future of research education, and Richard's praise for the University of Chicago's BASIC program.Key InsightsGPS was born from competing visions within the U.S. military. Richard Easton explains that the Navy and Air Force each had different ideas for navigation satellites in the 1960s. The Navy wanted mid-Earth orbits with autonomous atomic clocks, while the Air Force preferred ground-controlled repeaters in geostationary orbit. The eventual compromise in 1973 created the modern GPS structure—24 satellites in six constellations—which balanced accuracy, independence, and resilience.Atomic clocks made global navigation possible. Roger Easton's early insight was that improving atomic clock precision would one day enable real-time positioning. The hydrogen maser, developed in 1960, became the breakthrough technology that made GPS feasible. This innovation turned a theoretical idea into a working global system and also advanced timekeeping for scientific and financial applications.Civilian access to GPS was always intended. Contrary to popular belief, GPS wasn't a military secret turned public after the Korean airliner tragedy in 1983. Civilian receivers, such as TI's 4100 model, were already available in 1981. Reagan's 1983 announcement merely reaffirmed an existing policy that GPS would serve both military and civilian users.The Gulf War proved GPS's strategic value. During the 1991 conflict, U.S. and coalition forces used mostly civilian receivers after the Pentagon lifted “selective availability,” which intentionally degraded accuracy. GPS allowed troops to coordinate movement and strikes even during sandstorms, changing modern warfare.Secrecy and innovation were deeply intertwined. Easton recounts how classified projects like GRAB and POPPY—satellites disguised as scientific missions—laid technical groundwork for navigation systems. The crossover between secret defense projects and public science fueled breakthroughs but also obscured credit and understanding.Ending selective availability unleashed global applications. When the distortion feature was turned off in May 2000, GPS accuracy improved instantly, leading to new industries—geocaching, precision agriculture, logistics, and smartphone navigation. This marked GPS's shift from a defense tool to an everyday utility.Innovation's future may rely on decentralization. Reflecting on his father's era and today's landscape, Easton argues that bureaucratic “big science” has grown sluggish. He sees promise in smaller, independent innovators—helped by AI, cheaper satellites, and private space ventures like SpaceX—continuing the cycle of technological transformation that GPS began.

#FenceFam Let's start with I love what I do. Kevin Hohe with Complete Fence out of Chicago (a 43 million dollar a year company) asked to jump on his podcast, The Atomic Construction Podcast, and tell my story. I loved every second of this. Sometimes I like to tell my side and how it all started. Kevin is a brilliant businessman and it's an honor to be asked for an interview! Enjoy!   Sign up here: https://www.eventbrite.com/e/fence-games-2026-hosted-by-custom-machine-motioneering-inc-tickets-1790556575919?aff=ebdssbdestsearch   Sign Up for AFA University Here: https://www.americanfenceassociation.com/events/afa_university_fence_installation_school/275/   Everything FenceTech Here: https://www.americanfenceassociation.com/fencetech/2026/   Cheers! Remember to like, share, comment and REVIEW!   The Fence Industry Podcast Links: IG @TheFenceIndustryPodcast FB @TheFenceIndustryPodcastWithDanWheeler TikTok @TheFenceIndustryPodcast YouTube @TheFenceIndustryPodcastWithDanWheeler Visit TheFenceIndustryPodcast.com Email TheFenceIndustryPodcast@gmail.com Mr. Fence Companies:    IG @MrFenceAcademy FB @MrFenceAcademy TikTok @MrFenceAcademy YouTube @MrFenceAcademy Mr. Fence Tools https://mrfencetools.com Mr. Fence Academy https://mrfenceacademy.com   Gopherwood & Expert Stain and Seal IG @stainandsealexperts  FB @ExpertProfessionalWoodCare YouTube @Stain&SealExperts  FB Group Stain and Seal Expert's Staining University  Visit RealGoodStain.com Visit Gopherwood.us   Log Cabin Fence IG @Log_Cabin_Fence FB @LogCabinFence Visit LogCabinFence.com   Elite Technique Visit getelitetechnique.com   Greenwood Fence Visit greenwoodfence.com   FenceNews Visit fencenews.com   Ozark Fence & Supply promo code: TFIP15 for 15% off! Visit ozfence.com   Benji with CleverFox for all your FENCE website needs! Visit cleverfox.online   Stockade Staple Guns Visit stockade.com   Bullet Fence Systems Visit bulletfence.com   ZPost Metal Fence Posts Visit metalfencepost.com   The Fence Industry Podcast is Produced by "Rob The Producer" Connect with him at justrobnoble@gmail.com for availability and rates.  

Ein Flammkuchen-Ofenschieber als Musikinstrument? Willkommen in der Welt von Atomic Fruit! Die international besetzte Berliner Band verbindet Psychedelic Rock mit elektronischen Beats – und ungewöhnlichen Klangquellen. Mit ihrer neuen EP und dem Album "Serpentine" im Gepäck touren sie durch Europa. Wer sie live erleben will, hat am 30. Oktober im Badehaus Berlin die Chance – oder schon vorher bei einer exklusiven Live-Session im studioeins im Bikini Berlin.

Ein Flammkuchen-Ofenschieber als Musikinstrument? Willkommen in der Welt von Atomic Fruit! Die international besetzte Berliner Band verbindet Psychedelic Rock mit elektronischen Beats – und ungewöhnlichen Klangquellen. Mit ihrer neuen EP und dem Album "Serpentine" im Gepäck touren sie durch Europa. Wer sie live erleben will, hat am 30. Oktober im Badehaus Berlin die Chance – oder schon vorher bei einer exklusiven Live-Session im studioeins im Bikini Berlin.

Ein Flammkuchen-Ofenschieber als Musikinstrument? Willkommen in der Welt von Atomic Fruit! Die international besetzte Berliner Band verbindet Psychedelic Rock mit elektronischen Beats – und ungewöhnlichen Klangquellen. Mit ihrer neuen EP und dem Album "Serpentine" im Gepäck touren sie durch Europa. Wer sie live erleben will, hat am 30. Oktober im Badehaus Berlin die Chance – oder schon vorher bei einer exklusiven Live-Session im studioeins im Bikini Berlin.

Ein Flammkuchen-Ofenschieber als Musikinstrument? Willkommen in der Welt von Atomic Fruit! Die international besetzte Berliner Band verbindet Psychedelic Rock mit elektronischen Beats – und ungewöhnlichen Klangquellen. Mit ihrer neuen EP und dem Album "Serpentine" im Gepäck touren sie durch Europa. Wer sie live erleben will, hat am 30. Oktober im Badehaus Berlin die Chance – oder schon vorher bei einer exklusiven Live-Session im studioeins im Bikini Berlin.

Nearly a year and a half after our conversation first aired, Aaron Slodov and Atomic Industries have reached an important milestone worth celebrating. Atomic recently announced the close of its $25 million Series A, led by MaC Venture Capital and DTX Ventures, with participation from Narya and others, to accelerate the rollout of its AI-driven manufacturing platform.With this funding, Atomic is expanding its software-defined factory footprint and advancing the AI systems at the heart of its vision—one that has already moved from pilot to production, shipping parts to some of the world's most demanding OEMs. At its core, Atomic is working to strengthen America's industrial base by making the manufacturing of physical goods more localized, resilient, and technology-enabled.This felt like the perfect moment to revisit my conversation with Aaron, where we unpack his techno-industrialist philosophy, the deep history of Ohio manufacturing, and why the future of physical production matters so much for our country.So, with that timely update, please enjoy this timeless conversation from the Lay of The Land archives with Aaron Slodov, CEO of Atomic Industries.00:00:00 – The Rise of Techno-Industrialism00:05:56 – The Journey from Bits to Atoms00:10:41 – The Challenges of Manufacturing00:15:47 – Reindustrialization and the Post-Industrial Myth00:20:48 – Atomic Industries: Innovating Manufacturing00:25:42 – Exascaling the Industrial Base00:30:49 – The Future of Manufacturing Talent00:40:46 – The Shift in Manufacturing Careers00:42:50 – Incentivizing the Return to Manufacturing00:44:58 – Cultural Integration of Tech and Manufacturing00:50:38 – Defining Success in Modern Manufacturing00:52:03 – The Importance of a Techno-Industrial Framework00:56:12 – Policy and the Future of Manufacturing01:02:33 – The Potential of Reindustrialization01:05:57 – Storytelling as a Tool for Founders-----LINKS:https://www.linkedin.com/in/abslodov/https://twitter.com/aphysicisthttps://www.atomic.industries/https://www.piratewires.com/p/techno-industrialist-manifestohttps://twitter.com/newindustrials-----SPONSOR:Roundstone InsuranceRoundstone Insurance is proud to sponsor Lay of The Land. Founder and CEO, Michael Schroeder, has committed full-year support for the podcast, recognizing its alignment with the company's passion for entrepreneurship, innovation, and community leadership.Headquartered in Rocky River, Ohio, Roundstone was founded in 2005 with a vision to deliver better healthcare outcomes at a more affordable cost. To bring that vision to life, the company pioneered the group medical captive model — a self-funded health insurance solution that provides small and mid-sized businesses with greater control and significant savings.Over the past two decades, Roundstone has grown rapidly, creating nearly 200 jobs in Northeast Ohio. The company works closely with employers and benefits advisors to navigate the complexities of commercial health insurance and build custom plans that prioritize employee well-being over shareholder returns. By focusing on aligned incentives and better health outcomes, Roundstone is helping businesses save thousands in Per Employee Per Year healthcare costs.Roundstone Insurance — Built for entrepreneurs. Backed by innovation. Committed to Cleveland.-----Stay up to date by signing up for Lay of The Land's weekly newsletter — sign up here.Past guests include Justin Bibb (Mayor of Cleveland), Pat Conway (Great Lakes Brewing), Steve Potash (OverDrive), Umberto P. Fedeli (The Fedeli Group), Lila Mills (Signal Cleveland), Stewart Kohl (The Riverside Company), Mitch Kroll (Findaway — Acquired by Spotify), and over 200 other Cleveland Entrepreneurs.Connect with Jeffrey Stern on LinkedIn — https://www.linkedin.com/in/jeffreypstern/Follow Lay of The Land on X @podlayofthelandhttps://www.jeffreys.page/

Atomic 212°’s Chief Strategy Officer, Asier Carazo and Bupa's GM of Marketing, Naomi Driver once shared a common fear that permeates much of the industry: How does a brand advance the cause for the 20 per cent of Australians with a disability – without being unintentionally tokenistic or offensive? Driver says those concerns often stop her marketing peers from doing anything – she would know given it was also once her experience. Driver shares some personal anecdotes that are funny now but mortifying at the time: She once told Mike Rolls, who lives with a double amputation, she liked “keeping people on their toes … then realised I’d put my foot in my mouth”. Rolls “is a mate” and enjoyed making her feel uncomfortable for a few seconds. But Driver said it made her think even harder about the language used across Bupa’s creative and digital assets – and Bupa's Paralympics program around last year's event (with ads featuring Rolls, who’s humour helped shape the script) is a benchmark for what brands can and should do, according to Inclusively Made’s CEO, Paul Nunnari. Like Driver, Asier Carazo’s fears have also flipped. He cites Atomic 212° colleague, Senior Account Exec Angus McLeod as an advocate for the missing piece in media industry planning. McLeod lost his hearing after an accident and often experiences media that hasn’t taken into account people who are deaf or hard of hearing. “Working side by side with Angus is just understanding the reality of millions of Australians,” says Carazo. “Twenty per cent of Australians live with some form of disability. Are we even thinking about them when we put forward the media plan? Are we challenging publishers to include accessibility features on the ads? Are we challenging creative agencies to think about accessibility as a forethought, not as an afterthought?” Roy Morgan, the go-to source for media pros, started reporting on Australians living with disability within its database in the last quarter. That’s a win, adds Carazo, “but what I would love to see is greater genuine curiosity around understanding the reality of this country … As marketers, we spend hundreds of thousands of dollars on research and testing, but then you're not allocating any money to understanding how your audiences are able to consume media.” Inclusively Made has a framework for brands that do want to make inclusivity BAU. The key: “Don't let perfection get in the way of progress … just get the ball rolling,” says CEO Paul Nunnari. “It's not always going to be perfect, but at least having the conversation, seeing what are those low hanging fruits that can be achieved with minimal risk outputs is a really good place to start.” While Bupa’s Paralympics approach is the benchmark, per Nunnari, it can be as simple as having a wheelchair user in the background of an ad, having a coffee with a mate. “It doesn’t need to be highlighted, it doesn’t need to be inspirational. It’s just two blokes getting together having a coffee, right? It's the norm.”See omnystudio.com/listener for privacy information.

Donate (no account necessary) | Subscribe (account required) Join Bryan Dean Wright, former CIA Operations Officer, as he dives into today's top stories shaping America and the world. In this episode of The Wright Report, Bryan covers the nearing end of the government shutdown, Trump's legal win allowing National Guard deployments to Portland, a Supreme Court case testing whether drug users can own guns, and international developments involving Chinese espionage, satellite security, auto industry sabotage, and Bolivia's rejection of socialism.   Shutdown Nears Its End: White House advisor Kevin Hassett says the government shutdown will likely end this week as Democrats feel pressure from bad polling and looming state budget crises. Trump's Triple B funding bill cut Medicaid loopholes that helped finance health care for illegal immigrants, forcing blue states to raise taxes unless a deal is reached.   Court Clears Trump to Deploy the Guard: The Ninth Circuit ruled that Trump can federalize Oregon's National Guard to protect Portland's federal buildings from Antifa violence. Democrats argued the protests were “mostly peaceful,” with one judge claiming the frog-costumed rioters were “having fun.” Bryan calls the decision a reality check against political theater.   Immigration and America's Workforce: NPR reports activists in Chicago are blocking ICE operations while a new study projects Trump's deportation policies could reduce the U.S. population by 15 million over the next decade. Bryan argues higher wages and affordable housing will follow, saying, “We don't need to import our workforce — we can build our own.”   Supreme Court Weighs Gun Rights for Drug Users: The Court will decide whether people who use marijuana or other drugs can legally own firearms. The case follows a lower court ruling that found “no historical justification” for disarming sober citizens. Bryan invites listeners to weigh in on whether gun ownership and substance use should mix.   China's Atomic Clock Breach: Beijing accused the NSA of hacking its national atomic clock, which could disrupt GPS, banking, and military systems. The alleged cyber breach used the cell phones of Chinese scientists to access secure servers. Bryan calls it “proof that nothing online is truly offline.”   Satellites Leaking Secrets: U.S. researchers found that half of global satellite transmissions can be intercepted with basic equipment, exposing phone calls, texts, and even military data. Bryan warns listeners to “keep sensitive conversations offline.”   Dutch Seize Chinese-Owned Chipmaker: The Netherlands took control of Nexperia, a critical auto-chip supplier, after U.S. intelligence warned China planned to move production back home. The move could disrupt global car manufacturing and tighten supply chains further.   Bolivia Rejects Socialism: Voters ousted socialist leaders and elected conservative Rodrigo Paz, who vowed to restore ties with the U.S. and rebuild Bolivia's lithium-rich economy. Bryan says, “Bolivia's victory over socialism should be a warning to voters in New York City.”   "And you shall know the truth, and the truth shall make you free." - John 8:32     Keywords: government shutdown Kevin Hassett, Trump Triple B Medicaid reform, Ninth Circuit National Guard Portland, Antifa Oregon violence, NPR ICE protests Chicago, deportation workforce study, Supreme Court drug users gun rights, NSA China atomic clock hack, satellites data leak UC San Diego, Netherlands Nexperia chip takeover, Bolivia Rodrigo Paz conservative election

Dirk Arnold und Harald Müller-Huesmann ordnen neue Daten ein: ctDNA-gesteuerte Therapiestrategien, adjuvante und perioperative Immunkonzepte (u. a. ATOMIC, MATTERHORN) sowie Fortschritte bei RAS-gerichteten Therapien im Pankreaskarzinom.

Atomic-6 is an advanced composites solutions manufacturer providing products such as satellite solar arrays and Space Armor(TM), based in Atlanta. Founder & CEO Trevor Smith is our guest this week.

Basti und Christian schauen endlich den Kultfilm aus dem Hause Troma!

European Rocket Revolution: HyImpulse, a German rocket manufacturer, has secured €45 million in funding to accelerate the development of their SL1 rocket. This three-stage rocket, standing 33 meters tall, aims for its inaugural flight in 2027 and promises to enhance Europe's competitiveness in space access, especially for smaller payloads.Innovative Space Armor: Atomic 6 has introduced Space Armor, a new composite material designed to protect satellites and astronauts from space debris. This lightweight, customizable shield absorbs impacts without generating secondary fragments, potentially revolutionizing safety in low Earth orbit.Black Hole Jet Dynamics: Researchers at Goda University have shed light on how supermassive black holes produce powerful jets of plasma. Utilizing advanced simulations, they reveal the role of magnetic reconnection in enhancing energy extraction, contributing to our understanding of galaxy evolution.Inflated White Dwarfs Explained: New findings on white dwarfs in short-period binary systems indicate that tidal heating causes these stellar remnants to expand and heat up significantly. This discovery could reshape our understanding of type Ia supernova progenitors and the dynamics of binary star systems.Meteorite Misidentified as Gold: A surprising tale of an Australian prospector who mistook a 17-kilogram meteorite for a gold nugget. This H5 ordinary chondrite, dating back to the solar system's birth, highlights the serendipitous treasures that can fall from the sky.For more cosmic updates, visit our website at astronomydaily.io. Join our community on social media by searching for #AstroDailyPod on Facebook, X, YouTubeMusic, TikTok, and our new Instagram account! Don't forget to subscribe to the podcast on Apple Podcasts, Spotify, iHeartRadio, or wherever you get your podcasts.Thank you for tuning in. This is Anna and Avery signing off. Until next time, keep looking up and exploring the wonders of our universe.✍️ Episode ReferencesHigh Impulse SL1 Rocket Development[High Impulse](https://www.highimpulse.com/)Atomic 6 Space Armor Technology[Atomic 6](https://www.atomic6.com/)Black Hole Research Insights[Goda University](https://www.godauniversity.edu/)White Dwarf Studies[Astrophysics Journal](https://www.astrophysicsjournal.com/)Meteorite Discovery Story[Geological Society](https://www.geologicalsociety.com/)Astronomy Daily[Astronomy Daily](http://www.astronomydaily.io/)Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click away... Click HereSponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click Here

Singer, songwriter and member of the Mighty Pines, Neil Salsich joins Chris and Amy in-studio to promote Pines Fest' at Atomic by Jamo this Saturday.

In this powerful episode of The Mike Litton Experience, we sit down with George Zavershinsky, a former Soviet nuclear physicist turned Orthodox priest, bestselling author, and PhD in theology, to explore his dramatic life transformation and the story behind his new novel, Atomic Shepherd. ➡️ What happens when a man working at the height of […]

IMPORTANTE: SI NOS ESCUCHAS EN SPOTIFY, LOS PROGRAMAS BORRADOS ESTÁN DISPONIBLES EN EL RESTO DE PLATAFORMAS Bueno otro programa que cae y ya son 4 en un mes....a partir de ahora volveremos al ritmo quincenal y esperamos recuperar al traid....perdón al argentino. 00:00 Intro del programa. Resumen Comic Con de Malaga. Premios Ivoox. 20:00 Sección de Cine y Series. Hablamos de un montón de cosas (sin spoilers) aquí las tenéis: 1. Hombre Lobo (Skyshowtime) 2. Atomic (Skyshowtime) 3. Poker Face T2 (Skyshowtime) 4. Dexter Resurrección (Skyshowtime) 5. Hotel Costieri (Prime Video) 6. Tierra De Nadie (Prime Video) 7. El Último Encargo (Prime Video) 8. Ice Road: Venganza (Prime Video) 9. La Lista Final: Lobo Negro (Prime Video) 10. Pubertad (HBO Max) 11. Rey Y Conquistador (HBO Max) 12. Marvel Zombies (Disney+) 13. Solo Asesinatos En El Edificio T5 (Disney+) 14. El Centro (Movistar+) 15. Incontrolables (Netflix) 16. Jóvenes y Millonarios (Netflix) 17. Sin Medida (Netflix) 18. French Lover (Netflix) 19. Animal (Netflix) 20. Black Rabbit (Netflix) 21. Revival (SYFY) 1:40:39 Despedida, Recomendaciones y Concurso. ANIMAOS A ENTRAR AL GRUPO DE TELEGRAM!! Gracias por estar ahí un programa más!!! Y recordad: TENEMOS LISTA DE SPOTIFY CON TODA LA MÚSICA QUE HA SONADO EN EL PODCAST A LO LARGO DE ESTAS TEMPORADAS (Menos la canciones hechas con IA porque no se pueden subir allí). Esperamos que lo disfrutéis. ♥️ GRACIAS POR VUESTRO APOYO Y POR ESTAR SIEMPRE AHÍ!!! Únete a nuestro grupo de Telegram (ES GRATIS!!!!): https://t.me/seriesreality Déjanos tus comentarios y likes en IVOOX, Apple Podcast, Spreaker, Podimo, Castbox, TuneIn, PocketCast, Spotify, Amazon Music y en nuestra web: www.seriesrealitypodcast.com. Aceptamos café virtual en https://ko-fi.com/seriesreality1 Twitter: @seriesreality1 Instagram: Seriesreality1 YouTube: Series Reality Podcast email: seriesreality1@gmail.com

JCO PO author Dr. Asaf Maoz at Dana-Farber Cancer Institute shares insights into article, “Causes of Death Among Individuals with Lynch Syndrome in the Immunotherapy Era.” Host Dr. Rafeh Naqash and Dr. Maoz discuss the causes of death in individuals with LS and the evolving role of immunotherapy. TRANSCRIPT Dr. Rafeh Naqash: Hello, and welcome to JCO Precision Oncology Conversations, where we bring you engaging conversations with authors of clinically relevant and highly significant JCOPO articles. I'm your host, Dr. Rafeh Naqash, podcast editor for JCO Precision Oncology and Associate Professor Medicine, at the OU Health Stephenson Cancer Center. Today, I'm super thrilled to be joined by Dr. Asaf Maoz, Medical Oncologist at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and faculty at the Harvard Medical School, and also lead author on the JCO Precision Oncology article entitled "Causes of Death Among Individuals with Lynch Syndrome in the Immunotherapy Era." This publication will be a concurrent publication with an oral presentation at the annual CGA meeting. At the time of this recording, our guest's disclosures will be linked in the transcript. Asaf, I'm excited to welcome you on this podcast. Thank you for joining us today. Dr. Asaf Maoz: Thank you so much for highlighting our paper. Dr. Rafeh Naqash: Absolutely. And I was just talking to you that we met several years back when you were a trainee, and it looks like you've worked a lot in this field now, and it's very exciting to see that you consider JCOPO as a relevant home for some of your work. And the topic that you have published on is of significant interest to trainees from a precision medicine standpoint, to oncologists in general, covers a lot of aspects of immunotherapy. So, I'm really excited to talk to you about all of this. Dr. Asaf Maoz: Me too, me too. And yeah, I think JCOPO has great content in the area of cancer genetics and has done a lot to disseminate the knowledge in that area. Dr. Rafeh Naqash: Wonderful. So, let's get started and start off, given that we have hosts of different kinds of individuals who listen to this podcast, especially when driving from home to work or back, for the sake of making everything simple, can we start by asking you what is Lynch syndrome? How is it diagnosed? What are some of the main things to consider when you're trying to talk an individual where you suspect Lynch syndrome? Dr. Asaf Maoz: Lynch syndrome is an inherited predisposition to cancer, and it is common. So, we used to think that, or there's a general notion in the medical community that it is a rare condition, but we actually know now from multiple studies, including studies that look at the general population and do genetic testing regardless of any clinical phenotype, that Lynch syndrome is found in about 1 in 300 people in the general population. If you think about it in the United States, that means that there are over a million people living with Lynch syndrome in the United States. Unfortunately, most individuals with Lynch syndrome don't know they have Lynch syndrome at the current time, and that's where a lot of the efforts in the community are being made to help detect more individuals who have Lynch syndrome. Lynch syndrome is caused by pathogenic germline variants in mismatch repair genes, MLH1, MSH2, MSH6, or PMS2, or as a result of pathogenic variants in EPCAM that cause silencing of the MSH2 gene. Dr. Rafeh Naqash: Excellent. Thank you for that explanation. Now, one of the other things I also realized, similar to BRCA germline mutations, where you require a second hit for individuals with Lynch syndrome to have mismatch repair deficient cancers, you also require a second hit to have that second hit result in an MSI-high cancer. Could you help us understand the difference of these two concepts where generally Lynch syndrome is thought of to be cancers that are mismatch repair deficient, but that's not necessarily true for all cases as we see in your paper. Can you tease this out for us a little bit more? Dr. Asaf Maoz: Of course, of course. So, the germline defect is in one of the mismatch repair genes, and these genes are responsible for DNA mismatch repair, as their name implies. Now, in a normal cell, we think that one working copy is generally enough to maintain the mismatch repair machinery intact. What happens in tumors, as you alluded to, is that there is a second hit in the same mismatch repair gene that has the pathogenic germline variant, and that causes the mismatch repair machinery not to work anymore. And so what happens is that there is formation of mutations in the cancer cell that are not present in other cells in the body. And we know that there are specific types of mutations that are associated with defects in mismatch repair mechanisms, and those are associated a lot of times with frameshift mutations. And we have termed them ‘microsatellites'. So there are areas in the genome that have repeats, for example, you know, if you have AAAA or GAGA, and those areas are particularly susceptible to mutations when the mismatch repair machinery is not working. And so we can measure that with DNA microsatellite instability testing. But we can also get a sense of whether the mismatch repair machinery is functioning by looking at protein expression on the surface of cancer cells and by doing immunohistochemistry. More recently, we're also able to infer whether the mismatch repair machinery is working by doing next-generation sequencing and looking at many, many microsatellites and whether they have this DNA instability in the microsatellites. Dr. Rafeh Naqash: Excellent explanation. As a segue to what you just mentioned, and this reminds me of some work that one of my good friends, collaborators, Amin Nassar, whom you also know, I believe, had done a year and a half back, was published in Cancer Cell as a brief report, I believe, where the concept was that when you look at these mismatch repair deficient cancers, there is a difference between NGS testing, IHC testing, and maybe to some extent, PCR testing, where you can have discordances. Have you seen that in your clinical experience? What are some of your thoughts there? And if a trainee were to ask, what would be the gold standard to test individuals where you suspect mismatch repair deficient-related Lynch syndrome cancers? How would you test those individuals? Dr. Asaf Maoz: We do sometimes see discordance, you know, from large series, the concordance rate is very high, and in most series it's over 95%. And so from a practical perspective, if we're thinking about the recommendation to screen all colorectal cancer and all endometrial cancer for mismatch repair deficiency, I think either PCR-based testing or immunohistochemistry is acceptable because the concordance rate is very high. There are rare cases where it is not concordant, doing multiple of the tests makes sense at that time. If you think about the difference between the tests, the immunohistochemistry looks at protein expression, which is a surrogate for whether there is mismatch repair deficiency or not, right? Because ultimately, the mismatch repair deficiency is manifested in the mutations. So if the PCR does not show microsatellite instability and now NGS does not show microsatellite instability, the IHC may be a false positive. At the end of the day, the functional analysis of whether there are actually unstable microsatellites either by PCR or by NGS is what I would consider more informative. But IHC again is an excellent test and concordant with those results in over 95% of cases. Now there is also an issue of sampling. It's possible that there's heterogeneity within the tumor. We published a case in JCOPO about heterogeneity of the mismatch repair status, and that was both by immunohistochemistry, but also by PCR. So there are some caveats and interpreting these tests does require some expertise, and I'm always happy to chat with trainees or whoever has an interesting or challenging case. Dr. Rafeh Naqash: Thanks again for that very easy to understand explanation. Now going to management strategies, could you elaborate a little bit upon the neo-adjuvant data currently, or the metastatic data which I think more people are familiar with for immunotherapy in individuals with MSI-high cancers? Dr. Asaf Maoz: Yeah, that's an excellent question and obviously a very broad topic. Individuals with Lynch syndrome typically develop tumors that are mismatch repair deficient or microsatellite unstable. And we have seen over the last 15 years or so that these tumors, because they have a lot of mutations and because these mutations are very immunogenic, we have seen that they respond very well to immunotherapy. And this has been shown across disease sites and has been shown across disease settings. And for that reason, immunotherapy was approved for MSI-high or mismatch repair deficient cancer regardless of the anatomic site. It was the first tissue-agnostic approval by the FDA in 2017. And so there are exciting studies both in the metastatic setting where we see individuals who respond to immunotherapy for many years, and one could wonder whether their cancer is going to come back or not. And also in the earlier setting, for example, the Cercek et al. study in the New England Journal from Sloan Kettering, where they showed that neoadjuvant immunotherapy can cause durable responses for rectal cancer that is mismatch repair deficient. And in that series, the patients did not require surgery or radiation, which is standard of care for rectal cancer otherwise. And there's also exciting data in the adjuvant space, as was presented in ASCO by Dr. Sinicrope, the ATOMIC study, and many more efforts to bring immunotherapy into the treatment landscape for individuals with MSI-high cancer, including individuals with Lynch syndrome. Dr. Rafeh Naqash: A lot of activity, especially in the neo-adjuvant and adjuvant space over the last two years or so. Now going to the actual reason why we are here is your study. Could you tell us why you looked at this idea of patients who had Lynch syndrome and died, and the reasons for their death? What was the thought that triggered this project? Dr. Asaf Maoz: As we were talking about, we now know that immunotherapy really has changed the treatment landscape for individuals with Lynch syndrome, and that most cancers that individuals with Lynch syndrome do have this mismatch repair deficiency. But we also know that individuals with Lynch syndrome can develop tumors that do not have mismatch repair deficiency, and we call them mismatch repair proficient or microsatellite stable. And there was a series from Memorial Sloan Kettering showing that in colorectal cancer, about 10% of the tumors that individuals with Lynch syndrome developed did not have mismatch repair deficiency. In addition to that, we anecdotally saw that some of our patients with Lynch syndrome died of causes that were not mismatch repair deficient tumors. We wanted to see how that has changed since immunotherapy was approved in a tissue-agnostic manner, meaning that we could look at this regardless of where the cancer started, because we would anticipate that if the tumor was mismatch repair deficient, the patient would be able to access immunotherapy as standard of care. Dr. Rafeh Naqash: Thank you. And then you looked at different aspects of correlations with regards to individuals that had an MSI-high cancer with Lynch syndrome or an MSS cancer with Lynch syndrome. Could you elaborate on some of the important findings that you identified as well as some of the unusual findings that perhaps we did not know about, even though the sample size is limited, but what were some of the unique things that you did identify through this project? Dr. Asaf Maoz: The first question was what cause is leading to death in individuals with Lynch syndrome? And we had 54 patients that we identified that had died since the approval of immunotherapy in 2017, 44 of which died of cancer-related causes. And when we looked at cancer-related causes of death, we wanted to know how many of those were due to mismatch repair deficient tumors versus mismatch repair proficient tumors or MS-stable tumors. And we found, somewhat surprisingly, that 43% of patients in our cohort actually died of tumors that were microsatellite stable or mismatch repair proficient, meaning of tumors that are not typically associated with Lynch syndrome. This is not entirely surprising as a cause of death because we know that immunotherapy does not typically work for tumors that are microsatellite stable. And so in the metastatic setting, there are much less cases of durable remissions with treatment. But it was helpful to have that figure as an important benchmark. There are previous studies about causes of death in Lynch syndrome, and particularly from the Prospective Lynch Syndrome Database in Europe. Those have provided really important information about cause of death by cancer site, but they typically don't have mismatch repair status and are more difficult to interpret in that regard. They also don't include a large number of individuals who have PMS2 Lynch syndrome, which is the most common, but least penetrant form of Lynch syndrome. Dr. Rafeh Naqash: As far as the subtype of pathogenic germline variants is concerned, did you notice anything unusual? And I've always had this question, and you may know more about this data, is: In the bigger context of immunotherapy, does the type of the pathogenic germline variant for Lynch syndrome associated MSI-high cancers, does that impact or have an association with the kind of outcomes, how soon a cancer progresses or how many exceptional responders perhaps with MSI-high cancers actually have a certain specific pathogenic germline variant? Dr. Asaf Maoz: That's an excellent question, and certainly we need more data in that space. We know that the type of germline mutation, or the gene in which there is a germline pathogenic variant, determines to a large degree the cancer risk, right? So we know that individuals who have germline pathogenic variants in MLH1 or MSH2 have a much higher colorectal cancer risk than, for example, PMS2. We know that for PMS2, the risks are more limited to colorectal and endometrial, and may be lower risk of other cancers. We also know that, you know, the spectrum of disease may change based on the pathogenic germline variants. For example, individuals who have MSH2 associated Lynch syndrome have more risk of additional cancers in other organs like the urinary tract and other less common Lynch-associated tumors. The question about response to therapy is one where we have much less information. There are studies that are trying to assess this, but I don't think the answer is there yet. Some of the non-clinical data looks at how many mutations there are based on the pathogenic variant and what the nature of those mutations are, whether they're more frameshift or others. But I think we still need more clinical data to understand whether the response to immunotherapy differs. It's also complicated by the fact that the immunotherapy landscape is changing, especially in the metastatic setting, now with the approval of combination ipilimumab and nivolumab for first-line treatment of colorectal cancer that is microsatellite unstable. But in our study, we did find that, as you would expect, there is an enrichment in MS-stable cancers among those with PMS2 Lynch syndrome. Again, our denominator is those who died, right? So this is not the best way to look at the question whether this is overall true, that is more addressed by the study that Sloan Kettering published. But we do see, as we would anticipate, that there are more microsatellite stable cancers among those with PMS2 Lynch syndrome that died. Dr. Rafeh Naqash: A lot to uncover there for sure. This study and perhaps some of the other work that you're doing is slowly advancing our understanding of some of these concepts. So I'd like to shift gears to a couple of provocative questions that I generally like to ask. The first is, in your opinion, and you may or may not have data to back this up, which is okay, and that's why we're having a conversation about it. In your opinion, do you think the type or the quality of the neoantigen is different based on the pathogenic germline variant and a Lynch syndrome associated MSI-high cancer? Dr. Asaf Maoz: I think there are some data out there that, you know, I can't cite off the top of my mind, but there are some data out there that suggest that that may be the case. I think the key question is the quality, right? I think that whether these differences that are found on a molecular level also translate to a clinical difference in response is something that is unknown at this moment. Some people hypothesize that if the tumor has less neoantigens, there's less of a response to immunotherapy. But I think we really need to be careful before making those assertions on a clinical level. I do think it's a really important question that needs to be answered, among others because, you know, in the colorectal space, for example, where we have both the option of doing ipilimumab with nivolumab and the option of doing pembrolizumab, we don't really know which patients need the CTLA-4 blockade versus which patients can receive PD-1 blockade alone and avoid the potential excess toxicity of the CTLA-4 blockade. There are a lot of interesting questions there that still need to be answered. And of course, individuals with Lynch syndrome are just a fraction of those individuals who have MSI-high cancer. So there's also the question about whether non-Lynch syndrome associated MSI-high cancer responds differently to immunotherapy than Lynch syndrome associated MSI-high cancer. A lot of very interesting questions in the field for sure. Dr. Rafeh Naqash: Absolutely. My second question is more about trying to understand the role of ctDNA, MRD monitoring in individuals with Lynch syndrome. If somebody has a germline, you know, Lynch syndrome MSI-high cancer, when you do a tumor-informed ctDNA assessment, what do you capture generally there? Because, and this question stems from a discussion I've had with somebody regarding EGFR lung cancer, since I treat individuals with lung cancer, and the concept generally is that even if the tissue showed EGFR, but for MRD monitoring, when you do a barcoded sequence of different tumor specific mutations, it's not actually the EGFR that they track in the blood when they do ctDNA assessment. But from a Lynch syndrome standpoint, if you have a germline, right, which is the first hit, and then you have the somatic in the tumor, which is the second hit, are you aware or have you tried to look into this where what is exactly being followed if one had to follow MRD in a Lynch syndrome MSI-high colorectal cancer? Dr. Asaf Maoz: I think a lot of the MRD assays are proprietary, and so we don't receive information about what the mutations that are being tracked are. In general, the idea is to track mutations that we would not expect to disappear as part of resistant mechanisms. We want these to be truncal mutations. We want these to be mutations in which resistance is not expected to result in reversion mutations. But what specifically is being tracked is something that I don't know because these assays, the tumor-informed ones, are proprietary, and we don't get the results regarding specific mutations. When it's circulating tumor DNA that is not necessarily tumor-informed, we do get those results, but that is less so about the specific selection of mutations. Dr. Rafeh Naqash: Thank you for clarifying that question to some extent, of course, as you said, we don't know a lot, and we don't know what we don't know. That's the most important thing that I've learned in the process of understanding precision medicine and genomics, and it's a very fast-paced evolving field. Last question related to your project, what is the next step? Are you planning any next steps as a bigger multicenter study or validation of some sort? Dr. Asaf Maoz: There are two big questions that this study raises. One, is this true across multiple other sites, right? Because this is a single center study, and we really need additional centers to look at their data and validate whether they are also seeing that a substantial portion of deaths in individuals with Lynch syndrome are attributable to mismatch repair proficient cancer. The other question is whether we can look at specifically MSI-high cancer versus MS-stable cancer and understand what the mortality rate for each of those are. From a clinical perspective, it's important to counsel individuals with Lynch syndrome about general cancer screening outside of mismatch repair deficient tumors and to understand that there is also a risk of mismatch repair proficient tumors and that treatment for those tumors would be different. There's a lot of work to be done in the future. Another major area of need is to see whether tumors that are microsatellite stable can be sensitized to immunotherapy, and that is beyond the Lynch syndrome field, but that is something that certainly would benefit these individuals with Lynch syndrome who develop mismatch repair proficient cancer. Dr. Rafeh Naqash: That's very interesting to hear, and we'll look forward to seeing some of those developments shape in the next few years. Now, I'd like to spend a minute, minute and a half on you specifically as a researcher, clinician, scientist. Could you briefly highlight - because I remember meeting you several years back as a trainee, with your interest in genomics, computational research - could you briefly tell us what led you to hereditary cancer syndromes based on your research and work? What are some of the things that you learned along the way that other early career investigators can perhaps take lessons from? Dr. Asaf Maoz: Big questions there, thanks for asking. I got interested in the field of hereditary cancer syndromes when I came to the United States and started doing lab research in Stephen Gruber's lab at the time at USC. He's now at City of Hope. And my interest was originally looking at immunotherapy and immunology, but I went to the case conferences where we were learning about individuals with hereditary cancer, and those were kind of earlier days where we were still trying to figure out how to test and what the implications for these individuals would be. And through fellowship, I was also very interested in that, and I did my senior fellowship years with Dr. Yurgelun here at Dana-Farber, who is the director of the Lynch Syndrome Center. And I I think it's the combination between being able to treat individuals based on precision medicine and what the germline mutation is, but also the ability to prevent cancer and to develop strategies to intercept cancer early that is really appealing to me in this field. It's also a great field to be in because it's a small field. If you come to the CGA-IGC meeting, you'll be able to interact with everyone. Everyone is super collaborative, super nice, and I really recommend it to trainees. The CGA-IGC annual meeting is really a great opportunity to learn more and experience some of the advancement specifically in the GI hereditary space. Lessons for trainees. I think there are a lot of lessons that I could think about, but I think finding strong and supportive mentors is one of the things that has helped me most. I think that just having close relationship with your mentor, having frequent discussions and honest discussions about what is feasible, what is going to make a difference for your patients and your research and what you want to focus on is really important. And so I think if I had to choose one thing, I would say choose a mentor that you trust, that you feel you have a good relationship with, and that has the availability to support you. Dr. Rafeh Naqash: Thank you so much for those insightful comments, and thank you for sharing with us your journey, your project, and some of your interesting thoughts on this concept of hereditary cancers. Hopefully, we'll see more of this work being published in JCOPO through your lab or work from others. Dr. Asaf Maoz: Thank you so much. I appreciate the opportunity to be here. Dr. Rafeh Naqash: Thank you for listening to JCO Precision Oncology Conversations. Don't forget to give us a rating or review and be sure to subscribe so you never miss an episode. You can find all ASCO shows at ASCO.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.

Today, we are kicking off a new series, where we will debate and try to identify the best skis of the 21st Century from over 30 ski brands. So over the next couple of weeks, you're going to be hearing our choices, but we are also going to be sending out a survey to our BLISTER+ members, Digital Access Pass members, and a number of pro athletes and product designers around the ski industry. Then, in a few weeks, we'll discuss how our selections match up with all of your answers. And finally, for the grand finale of this series, we're going to offer our choices for the Very Best Skis of the Century — can we whittle things down to a top 10? A top 3? To a single ski? We're going to find out, and it's certainly going to be fun trying.Today, Jonathan Ellsworth, Luke Koppa, Paul Forward, and our great friend, Rob Dickinson, get the conversation going.Note: We Want to Hear From You!Please let us know if there's a topic you'd like us to cover or a guest you'd like us to have on GEAR:30. Or if you'd like to nominate yourself for a ‘Gear Therapy' episode, let us know that, too! You can email us at info@blisterreview.comRELATED LINKS:Our Digital Buyer's Guide: Read NowBLISTER+ Get Yourself CoveredDiscounted Summit Registration for BLISTER+ MembersNon-Member Registration: Blister Summit 2026Order Our 25/26 Winter Buyer's GuideGet Our Newsletter & Weekly Gear GiveawaysTOPICS & TIMES:New BLISTER+ Members (2:44)Rossignol (7:58)Aznes (17:33)Volkl (20:47)Kastle (30:22)Fischer (33:30)Stochli (39:53)Elan (43:02)Head (46:51)Blizzard (53:46)Atomic (59:59)Nordica (1:05:38)K2 (1:10:45)Dynastar (1:17:01)Salomon (1:20:16)Line (1:23:55)CHECK OUT OUR OTHER PODCASTS:Blister CinematicCRAFTEDBikes & Big IdeasBlister Podcast Hosted on Acast. See acast.com/privacy for more information.

We review the Best Ski Boots for the new 2026 winter season, covering the best piste, all mountain and freeride ski boots.   Host Iain Martin was joined by The Ski Podcast's equipment expert Al Morgan and Frazer Shand, Operations Manager at Profeet. This special episode has been made possible by the Profeet Ski Boot Lab, based in south-west London. Profeet offer expert ski boot fitting, custom insoles and ski boot modifications. SHOW NOTES Watch our ‘Best Skis of 2026' video Ski Boot definitions and terms…  Shell (4:00)  Last (4:30)  Mondopoint (5:45)  Flex (7:15)  Liner (8:45)  BOA (10:15)  Powerstrap (12:30)  Walk mode and Grip Walk (13:30) Sustainability (16:30) Function, Fit and Footbeds (18:15) Find out about the fitting process at the Profeet Ski Boot Lab (18:45)  Profeet start with a biomechanical analysis and foot scan (19:45) Custom insoles (23:00) Customisation (24:00) Visiting the Dalbello factory (34:00) Get your free tickets to the London Snow Show (55:45) Profeet will be exhibiting at the London Snow Show (56:30) THE BEST SKI BOOTS OF 2026   Piste and All-Mountain Ski Boots K2 Cortex Zonal 120 BOA(26:30) £625 SIZES (MP): 24.5 - 28.5 VOLUME: Low LAST (mm): 96 – 98              WEIGHT (per boot): 2,179g (26.5MP) These are incredible boots, delivering a ton of support and superb hold, in a flex that will work far better for most skiers. K2 has offered single BOA on higher-volume boots previously, but the Cortex is the slimmest profile they've integrated this into, and this time you get the benefit of the dial and cable system on the shell and cuff, on the Zonal models.   Non-Zonal Cortex models have BOA only over the foot. The softer material over the instep makes it a tad easier to get into the boot, and aids shell wrapping, when you dial in the snugness. The heel has a slimmer internal profile than their other boots, and the lace-up liner adds to the excellent hold you get.    You also get a cam power strap, which is not that common on 120 flex boots, and I much prefer this strap to a Velcro option. There are two bolts on the spine, and you can remove the top one if you want a more forgiving flex profile. They offer the Cortex range right up to the £725, all-singing, all-dancing 140 flex model, which is the only one with pin inserts in the toe. Dalbello Veloce Space 120 Dual(32:00) £580 SIZES (MP): 24.5 - 30.5  VOLUME: Medium  LAST (mm): 101  FLEX: 120 WEIGHT (per boot): 2,050g (27.5MP) This is the first season Dalbello has offered BOA on their boots, and they've added Dual and Single BOA models to their range, in this new Veloce Space line. Dual BOA is available on the 105, 120 and 130 flex models.    The shell and cuff on the 120 are made of PU. They inject differing hardnesses of plastic, to take advantage of the phenomenal wrap you get with the BOA system. It also makes the boots easier to get on. The mouldable liner is beautifully comfortable, and the Adaptive Tongue construction, integrating memory foam, is so nice for the shins, also helping with instep comfort. The pre-shaped Ankle Sense zones enhance the heel hold.  The 120 is also available in a single BOA (£540), with regular cuff buckle closure, like the 110, 100, 95 and 85. These single BOA versions get a lever you can release on the spine, allowing an easier walking motion. Head Kalibre 110 MV BOA 2(36:00) £510 SIZES (MP): 25.0 - 30.5  VOLUME: Medium LAST (mm): 100 WEIGHT (per boot): No stated weights    This is Head's Dual BOA offering and is totally new. The Kalibre boots have a clean aesthetic. They inject different hardnesses or plastic into the shell, to take advantage of the superb wrap of the BOA H+i1 system.  Kaliber, like many BOA offerings, is a medium volume fit, with 100mm last. They have a new liner for this range too, called Synapse. They weave in Graphene for tech-level temperature regulation.  The 110 has a Velcro power strap, although £600 130 flex has a claw strap. The Kaliber line features a greater range of flexes in single BOA and four clip versions, but the BOA2 models are pretty awesome. This is the only 110 flex dual BOA model we know of for this season. Freeride Ski Boots   Rossignol Alltrack 130 Elite LV LT GW (40:30) £625  SIZES (MP): 24.0 – 29.5  WALK MODE: Y, no stated ROM VOLUME: Low LAST (mm): 98  FLEX: 130  WEIGHT (per boot): 1,825g (no stated size)  The Alltrack line has been redesigned for this season. They've added BOA to shell of the 102mm HV models, but we tested the narrow-last Elite LT model, which has tech inserts in the toe and heel.  Even though these are 98mm last, low-volume boots, they have more room inside than some other LV boots in this category. They look sensational, have heat-mouldable liners and an innovative ski-walk mode, inspired by the work done developing the Vizion easy (rear) entry boots.  Flip the ski-walk mode lever up, and the rear of the boot can tilt back, with the liner attached to the rear of the cuff with a loop to hold it in place, in order that you can easily slide in. Fasten the buckles, flex forward and the walk mode locks into the ski position, ready for the descent. To tour, flip the rear lever up, loosen the cuff buckles and power strap, and off you go.  This boot skied beautifully, and I just love the way the Dual Core shells flex.   Armada AR One 130 (43:00) £580 SIZES (MP): 24.5 - 29.5 WALK MODE: N  VOLUME: Medium LAST (mm): 100 FLEX: 130  WEIGHT (per boot):100g (26.5MP) The AR One is Armada's first ever ski boot and it's a very impressive hybrid cabrio design blending Alpine and freeski design. Designed by Armada, it's built in partnership with their sister company, Atomic.  It's a medium volume unisex boot, with a 100mm last in a size 26.5MP, in 5 flexes. The 120 and 130 are only available from 24.5MP and up, whilst the 90, 100 and 110 go down to 23.5MP.  The heat mouldable shell and liner, along with excellent out-of-the-box shaping, ensures a very comfy, and customisable, fit. A tool free volume adjuster lets you create space for pressured calves, and most parts are user replaceable, improving sustainability. The top three flexes are pure PU shell, cuff and tongue, for a smooth ride. The rubber boot board does a fab job of smoothing landings and judders. The buckle setup is very different, especially the instep buckle and cable Y-configuration, securely holding you in the heel pocket.  The 130 and 110 share the Team liner, whilst the others have the Pro Liner, which lacks the repositionable tongue, which allows you to adjust volume and fit over the foot. The elasticate claw power-strap on these two flexes is a superb, but the others only get a Velcro strap. Toe pin inserts on the 130 allows use with hybrid bindings like the Shift, Duke PT and the new ATK Hy.  This is a fabulous downhill ski boot, with excellent lateral response, impressive power, it's smooth with great damping and superb heel hold.  Scarpa 4 Quattro GT Woman (45:45) £580                                  SIZES (MP):  22.5 – 27.0 WALK MODE: Y, 61° ROM  VOLUME: Medium LAST (mm): 101 FLEX: 90 / 110  WEIGHT (per boot): 1,510g (25.0MP)   The 4-Quattro range has been an incredible success, especially the XT model which has been a benchmark freeride touring boot in recent seasons. Scarpa's dropped the XT for this winter, but they've updated the SL, they still have the 4-Quattro Pro, which Nikolai Schirmer uses and helped develop, and they've added in a new GT model in a woman's and man's version.  The GT has a roomier fit, has a new 4Pro Flex GT Intuition liner, and is the warmest 4-Quattro model. You get a Velcro power strap, rather than a claw version seen on the others, and it's made using Desmopan plastic for the shell and cuff, rather than Pebax Renew, although all Quattro models have a Pebax tongue. The Desmopan CQ MBC uses bio-circular TPU, enhancing the sustainability, and reducing the CO2 footprint. You don't get the Carbon Core construction of the SL or Pro, but the GT skis better.    They're an easier flex for lighter or less aggressive riders, and the fact these are such great value is a bonus. PROFEET'S CHOICE Technica Mach1 LV 130, £550 (48:30) Updated for this season with a fully redesigned shell and liner, offering a touch more instep depth but still an excellent low volume fit. From a boot fitter point of view, they are also a pleasure to work on with design features allowing for easier customisation of the shell. Feedback (51:00) I enjoy all feedback about the show, so if you enjoyed this episode, or if you have any questions about skis we didn't cover, then please let us know by leaving a comment at Instagram or Facebook – we are @theskipodcast – or by dropping me an email theskipodcast@gmail.com. You can also follow us on WhatsApp for exclusive material released ahead of the podcast. Adam Matthews on Instagram enjoyed our ‘Best Skis' episode: “Great podcast. Been looking forward to this since last year's episode” Rick on YouTube loved Al's choice of the Volkl V.Werks 100: “I rode this a lot last winter, so much that I crashed and busted my knee. But seriously, it´s an absolutely amazing ski.” There are now 276 episodes of The Ski Podcast to catch up with. You can do that too, there is so much to listen to in our back catalog, just go to theskipodcast.com and search around the tags and categories: you're bound to find something of interest.   If you enjoyed this episode and would like to help the podcast, there are three things you can do:   -          you can follow us, or subscribe, so you never miss an episode -          you can give us a review on Apple Podcasts or leave a comment on Spotify -          And, if you're booking ski hire this winter, don't forget that you can help The Ski Podcast and save yourself some money on your ski hire by using the code ‘SKIPODCAST' when you book at intersportrent.com. You'll get a guaranteed additional discount, or simply take this link for your discount to be automatically applied. 

A screencast from Chapter 3 in CH 221 entitled “Atomic Electron Configurations”

Hey everyone an amalgamation of 2 episodes we did recently we talked about "How I Fell In Love With The Void" - the latest offering from the wonder Connecticut Noise Rock band Intercourse and we also chatted about the new EP "With Skull Crushing Force" from Atomic Rule, the new project from former Every Time I Die riff-lord Andy Williams and we compared it to the latest releases from the other post-ETID breakup bands Many Eyes and Better Lovers to enjoy these things to their fullest we recommend heading to our Youtube channel where we upload these in video format thanks a lot love you all Join the Discord! It's full of people sharing sick heavy music all the time.

Send us a textThis week on Late to Grid, Bill sits down with Nisa Borghi to talk about her path into motorsports—from giving her VW GTI a personality on Instagram, to celebrating 100K miles at her first autocross, to taking on the challenge of a rear-wheel-drive Miata.Nisa shares what it was like stepping into the SCCA community, co-driving with her husband, flagging at Nelson Ledges, and learning the ropes as a woman in motorsports. From trackside lessons to social media connections, her story shows how passion, persistence, and community fuel the journey.Whether you're curious about autocross, looking for your motorsports tribe, or just love a good “late to grid” story—you'll find plenty of inspiration in this episode.Race season is here. If you need to catch up on setup, or have something that needs repaired, you need to be Atomic prepped. Get to https://atomicautosports.com/ to get your car ready to get out there next weekend. If you're chasing lap times, you need a track ready setup for your car. Get to AtomicAutosports.com to get your car scheduled to get you on the podium. Track ready setups for time trial drivers and others Thanks for listening and taking an interest in growing grassroots racing. The Late To Grid podcast shares the stories and inspiration that help listeners along their motorsports journey. Find all episodes on the Atomic Autosports website.

In the wake of the nuclear attacks on Japan, the official Allied line was that radiation sickness was not a danger. Yet, as this Long Read written by Steve O'Hagan reveals, the first Western journalist to witness the effects on the people of Hiroshima told a very different story. HistoryExtra Long Reads brings you the best articles from BBC History Magazine, direct to your ears. Today's feature originally appeared in the September 2025 issue, and has been voiced in partnership with the RNIB. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Trevor Smith, Founder and CEO of Atomic-6, shares his origin story and journey from a commercial real estate broker to leading a company specializing in near-theoretical high-performance composites. Some of Atomic-6's innovations include:  - A composite debris shield for the International Space Station, which outperformed traditional aluminum shields in tests. - Development on a redeployable solar array system, Light Wing, which offers significantly improved space power efficiency. - Composite Radomes that provide a great balance of functionality and light-weighting - And so much more - with video examples!! Trevor also shares on the importance of incentive alignment and 'delusional optimism' in order to succeed and lead in entrepreneurship. Learn more about Atomic-6 in this episode and make sure to check out their website for more: https://www.atomic-6.com/ Timestamps: 00:00 Trevor Smith's Role as CEO and The Power of Incentive Alignment 02:22 Trevor's Origin Story and Early Career 06:32 Atomic-6's Early Days and Initial Challenges 17:57 Developing High-Performance Composites 21:16 Atomic Six's Defense and Space Applications 25:10 Space Armor and Its Applications 36:23 Light Wing: Redeployable Solar Arrays 44:20 Light Wing's Deployment and Benefits 44:20 Future of Space and Defense 56:61 Trevor's Advice for Entrepreneurs & "Delusional" Optimism We'd like to thank our sponsors: AG3D Printing (go to ag3d-printing.com to learn more & start 3D printing today!) Today In Space Merch: James Webb Space Telescope Model (3DPrinted) https://ag3dprinting.etsy.com/listing/1839142903 SpaceX Starship-Inspired Rocket Pen (3DPrinted) https://ag3dprinting.etsy.com/listing/1602850640 Blue Origin New Glenn-inspired Rocket Pen (3DPrinted) https://ag3dprinting.etsy.com/listing/1859644348 Support the podcast: • Buy a 3D printed gift from our shop - ag3dprinting.etsy.com • Get a free quote on your next 3D printing project at ag3d-printing.com • Donate at todayinspace.net

This week we don broad hats and cravats to pass as riverboat gamblers en route to america's most culturally productive delta, hoping the lawless highwayman strategy of putting an entire paycheck on red yields a good result. If not, at least we have the paint-peeling shriek of Mississippi's own ATOMIC JEFFERSON to keep us occupied in our cells.

In this episode of Cherokee Business Radio, Joshua Kornitsky talks with Trevor Smith, founder and CEO of Atomic-6. Trevor shares his journey from real estate to pioneering advanced composite materials for defense and aerospace. The discussion covers Atomic-6's innovative deployable solar arrays and space armor, designed to improve satellite efficiency and protection. Trevor highlights the […]

In this episode of Cherokee Business Radio, Joshua Kornitsky talks with Trevor Smith, founder and CEO of Atomic-6. Trevor shares his journey from real estate to pioneering advanced composite materials for defense and aerospace. The discussion covers Atomic-6's innovative deployable solar arrays and space armor, designed to improve satellite efficiency and protection. Trevor highlights the […] The post The Power of Composites: Transforming Defense and Space with Atomic-6 appeared first on Business RadioX ®.

Sabaidee, Konichiwa, and Hello! Welcome to another episode of Thip Khao Talk Podcast. I'm Arianna Sinlapasai-Okamura, an advocacy ambassador for Legacies of War and I have the honor today of welcoming to the podcast our friends, Karin Tanabe and Victoria Kelly, producers and story tellers of their documentary, Atomic Echoes. Today's episode will be in recognition of the International Day for the total elimination of Nuclear Weapons. To introduce our distinguished guests:Karin Tanabe is the author of seven novels. She is a former Politico reporter and a frequent contributor to The Washington Post Book World. Her writing has also appeared in the Miami Herald, Chicago Tribune, and Newsday. She has been featured as an entertainment, style, and politics expert on Entertainment Tonight, CNN, and the CBS Early Show. Karin is a graduate of Vassar College and lives in Washington, D.C.Victoria Kelly is also an accomplished author of four books of fiction and poetry. Her works have been selected for Best American Poetry series and her writing has appeared in The Chicago Tribune, The San Francisco Chronicle, The Baltimore Sun amongst others.  She is a graduate of Harvard University and lives in Maryland.Thank you for tuning into Thip Khao Talk brought to you by our Innovators Sponsors Akin Gump and Article 22. Please continue to listen and follow us on Spotify and Apple Podcasts. The theme music used in this podcast are by the Lao Jazzanova Band from Vientiane, Laoshttps://atomicechoesfilm.com/https://www.legaciesofwar.org/

We review the Best Skis for the new 2026 winter season, covering the best piste skis, best all mountain skis and freeride skis. Host Iain Martin was joined by The Ski Podcast's equipment expert Al Morgan.  Tirol in Austria sponsors The Ski Podcast, which means that this winter we'll be able to find out more about some of the great destinations in Tirol, and how you can connect with the wonderful ‘feeling of life' there.  SHOW NOTES Iain and Al will be at the London Snow Show in October (3:00) Best Skis of 2026 means the best skis of winter 2025/26 (4:00) What are the different types of skis (4:15) How important is that figure for width under your foot? (7:45) What is meant by ‘side cut'? (10:00) What is a ‘rocker? (12:00) How long should your skis be? (15:15) Is sustainability still important in ski production? (18:45) The Ski Sustainability Forum is organised by POW, Atomic and FESI (21:00) When and where did testing take place? (22:15) SIGB is the Snowsport Industries of Great Britain (22:45) Most testing takes place at SIGB's annual ski test in La Clusaz (23:15) How much do bindings cost? (25:00) THE BEST PISTE SKIS OF WINTER 2026  K2 Blur 74 W (women) (26:30) £600 / 148cm-169cm Blur is K2's new piste ski range for winter 25/26. The 74W has a little lift through the front and back, is built around their aspen wood core and uses Flax with channels milled into it.  They only do this in this ski and the Blur 79W to enhance agility. It should also save a little weight, although the 74 is about performance and a perfect partner for advanced and expert female skiers shredding the groomers.   It has a 13.9m radius in the longest length and testers reported it as silky smooth, easy to ski yet snappy, with great boost turn-to-turn. It's super reactive underfoot, quick to pivot and rotate for short turns.  Nordica Dobermann Multipista DC FDT (29:00) £930 including binding, 160cm-185cm The Multipista is new for this season, focussed equally on fun and performance. It may look similar to the Steadfast skis in its outline, but there's a lot more going on than simply a curvy figure.  It has Dobermann in the name, which hints at this ski's powerful drive, and when you open the throttle you're rewarded by the bucketload!  The rise though the front and back, paired with the taper at each end, means you never feel like your locked into a turn. It can lay trenches on the groomers, but if you want to nip off the side, take on some slush or get a little airtime, it's as composed as you could ask for.   It's built around their Energy 2 Ti Double Core (DC) construction. An elastomer layer is sandwiched between two beech and poplar wood cores, beefed up by two layers of Titanal metal, one above the wood-elastomer sandwich and one below.  Even though Nordica states the ski as having a Full Camber Profile, it has a longer rise through the shovel and tail than a regular full camber ski. This rocker profile is part of the Multipista's magic, bringing a delightfully versatile nature. The tapered profile through the shovel and tail further adds to its performance across a range of conditions. The 74mm waist width, in all lengths, partners with their race on-piste shape underfoot for confidence-rocketing grip. This width is bang-on the money, with plenty of punch through the edge and enough float and stability to tackle a broad array of terrain and snow conditions. THE BEST ALL MOUNTAIN SKIS OF WINTER 2026 Völkl V.Werks 100(32:00) £1,750 flat, 170cm-186cm Völkl has taken all they've learnt from ski manufacturing and turned the dial up to eleven with this ski! The company was founded in 1923, and in honour of this they have made exactly 1923 of these skis, with a retail price of €1923.   This ski is see-through. If you place your hand behind the ski, when holding it up to the light, you can see where your hand is. It's quite spectacular. It also highlights the complex structure they've perfected for the fibre placement.  They combine carbon and natural flax fibres, which work in harmony with the superb 3D H-Woodcore. This is made of two enviro friendly FSC-certified poplar and beech cores, with a central reinforcement, and this all has a very noticeable and technical 3D shape.  The fibres, translucent layer and wood core allows the designers to transfer the movements and forces from the skier through the ski and to the edges, for a ridiculously intuitive control. You get a regular camber underfoot but enough rocker in the shovel and tail for a mega-versatile shape. Atomic Maven 88 CTI (Women) (35:00) £570 without bindings, 147cm-172cm   This ski is based around an ash and poplar wood core, boosted by the addition of carbon and Titanal. These laminates add greater damping and energy to the ski, whilst helping to keep the ski light.  The change of shape through the shovel, as we saw in the wider Maverick and Maven models last season, keeps this ski incredibly playful. This HRZN 3D Maverick/Maven tech sees the wood core extend right up to the very front of the ski, designed to improve stability and smoothness when charging hard.  These skis can certainly be skied fast, but the thing you notice most with all skis with HRZN tech is just how much it enhances the fun nature of the skis. They are not twin-tips, and have a directional shape, although the rise in the back means you can ski switch if you really want to. Atomic builds in a 15% rocker through the shovel and a 10% rocker at the back, with standard camber in the middle of the ski. Salomon Stance Pro 86(Unisex) (38:00) £640 flat, 151cm-185cm   Salomon's Stance range sees significant change, taking what were already great skis and making them industry leading.  It has a full poplar wood core, with the Powerflex Ti metal layer sitting full width underfoot and tapering out in front of and behind the binding. The metal edge is made thicker to aid grip and power, and will endure more services, therefore lasting longer. The base has a 50% recycled content. The profile delivers regular camber underfoot with a 15% rocker through the front and a milder 12% rocker at the rear. THE BEST FREERIDE SKIS OF WINTER 2026 (40:00) Head Kore 99 Ti W(Women) (40:30) £650 without bindings, 156cm-177cm   The Kore skis are redesigned for this season. This 99mm underfoot model has the same length options as the women's Kore 97 of last season, but otherwise it's a very different ski.  Where the men's new Kore skis use beech and karuba, the women's Kore models combine poplar with PET (polyethylene terephthalate), which is a thermoplastic polyester polymer. Think of your favourite fleece, and the chances are it's made of the same material.  This is complimented by a layer of Titanal, using at least 40% recycled material, above and below the core, along with a Graphene layer between the metal and top of the core. They add a damping layer between the bottom metal layer and the edges of the ski, to further smoothen the ride.  Again, as in the men's, they add flax to the boundary of the topsheet to improve durability. Rocker front and back, with standard camber underfoot, gives the ski it's undeniable freeride profile.   Salomon QST 100(Unisex) (43:30) £570 without bindings, 148cm-188cm   New for this season in widths ranging from 92 through to 106, the 100 is an incredible freeride ski and was a hit with everyone at testing. It's a unisex model, offered in a choice of two colours.  The new QST's have full poplar wood cores with basalt and glass fibres, as well as Salomon's proven Cork Damplifier, where they inlay a cork and TPU border at the tip and tail to dampen vibrations. The 106 has a 22% rocker up front and 18% rocker in the tail. As you step down in width to 100 then 94, they reduce the rocker proportion by 1% at each end, for each drop in width.   FEEDBACK I enjoy all feedback about the show, so if you enjoyed this episode, or if you have any questions about skis we didn't cover, then please let us know by leaving a comment at Instagram or Facebook – we are @theskipodcast – or by dropping me an email theskipodcast@gmail.com There are now 273 episodes of The Ski Podcast to catch up with. There is so much to listen to in our back catalog, just go to theskipodcast.com and search around the tags and categories: you're bound to find something of interest.   If you enjoyed this episode and would like to help the podcast, there are three things you can do:   -          Follow us, or subscribe, so you never miss an episode -          Give us a review on Apple Podcasts or leave a comment on Spotify -          Help The Ski Podcast and save yourself some money on your ski hire by using the code ‘SKIPODCAST' when you book at intersportrent.com. You'll get a guaranteed additional discount, or simply take this link for your discount to be automatically applied.  You can also follow us on WhatsApp for exclusive material released ahead of the podcast.

There are not many fintechs that can say they work with nine of the top ten banks in the United States. Or that they are working directly on deep integrations with the likes of Apple and Amazon. Meet Jordan Wright, CEO and Co-Founder of Atomic, who can say all those things.While Atomic started in direct deposit switching, a now relatively mature fintech product, what they have been working on recently is truly groundbreaking technology. They have built what they call a “Payments Hub” and have implementations happening at large banks now. This will make it much easier for consumers not just to manage their recurring payments but to take action, which has been a crucial missing piece.In this podcast you will learn:The founding story of Atomic.What they mean by building a “framework for connected banking.”What Jordan is most proud of that they have built at Atomic.What their offering looks like inside a banking app.Why they are reaching out to merchants and connect them one by one.What happens behind the scenes for their TrueAuth product.Why they have focused their technology on the mobile-centric experience.How they were able to work directly with the likes of Apple and Amazon.How they are engaging differently with the large banks than the fintechs.What the flow is like when you are opening a bank account powered by Atomic.How they are working with the large credit card companies.Why they are focused on taking action rather than just information.How they are using Generative AI in their products and within the company.How Jordan thinks this new technology will impact financial health.When we will start seeing payments hubs at large banks.What Atomic is working on in the near term future.Connect with Fintech One-on-One: Tweet me @PeterRenton Connect with me on LinkedIn Find previous Fintech One-on-One episodes

The Smart 7 is an award winning daily podcast, in association with METRO, that gives you everything you need to know in 7 minutes, at 7am, 7 days a week…With over 19 million downloads and consistently charting, including as No. 1 News Podcast on Spotify, we're a trusted source for people every day and we've won Gold at the Signal International Podcast awardsIf you're enjoying it, please follow, share, or even post a review, it all helps... Today's episode includes the following:https://x.com/i/status/1970804804432621803 https://x.com/i/status/1970744291120345173https://x.com/i/status/1970865822227661204 https://x.com/i/status/1970767633827192945 https://x.com/i/status/1970722225562230823 https://x.com/i/status/1970716608646480313 https://x.com/i/status/1970984087558017494 https://x.com/i/status/1970730009430991049 https://youtu.be/uUmdaUaGTPM?list=RDuUmdaUaGTPM Contact us over @TheSmart7pod or visit www.thesmart7.com or find out more at www.metro.co.uk Voiced by Jamie East, using AI, written by Liam Thompson, researched by Lucie Lewis and produced by Daft Doris. Hosted on Acast. See acast.com/privacy for more information.

Game 1:Series of 50s to start the gameFirst killer has 70% goal participation in the tournamentDaniel hit a post that really could have gone inNRG scores after keeping Ultimates to low boost and using demosNRG consistently keeps it in the Ultimates side and score againSide note, catching ball into airdribbleNRG keeps them to low boost and sees out the first gameGame 2:First Killer scores first for Ultimates with a 101 kph shot off the crossbar, catches NRG not paying attentionSide Note, practicing bar down shots, is that a thing?NRG has a lot more East-West carries or crosses than UltimatesAtomic almost scores on a double tap, but Daniel manages to come in a clean up 1-1Beast most almost scores, NRG has two more chances but don't manage to scoreDefensive mixups and low boost for the Ultimates but they don't manage to get punished before overtimeFirst killer with a solo plays wins it for the UltimatesGame 3:Atomic fakes to get NRG the lead the third timePassing play into Atomic double tap 2-0 lead, Atomic feeling goodLj fakes out play and First Killer gets the Ultimates first goal of game 3Ultimates have switched out their timing and patternNRG seems to be more consistently in the opposition end, Atomic demos and redirects to get his thirdNRG wins the game 4-2Game 4:After a time out the ultimate start off game 4 aggressivelyChronic finds an opening and bangs it in 1-0 UltimatesPressure from NRG East-West Coast and constant demosNRG Blocks on clears get a 50 that sets up AtomicGame goes to overtime, seems like NRG are keeping their strategyRelentless pressureBeast Mode passes to Atomic to scoreGame 5:Daniel pinches and keeps with the ball to tap it in (been quiet the whole series from a goal perspective)Chronic messes with NRG and lets Firstkiller get a double tapChronic makes a crazy save off the lineBeastmode capitalizes on Ultimates mistakes (some bumps included)NRG should really win from hereFirstkiller beats two and passes it to LJ to tie it upPassivity?Great Passiving from Ultimates for the next goalNRG misses and Ultimates survive for game 6Game 6:Chronic gets a dunk early and momentum is in the Ultimates favourMore side to side passes form the UltimatesAtomic scores after Chronic dodges a bumpGreat pass and Chronic scores, RULE 1 BROKENNRG had the CLOSEST POSTDaniel sneaks a goal in by faking a pass and seeing the opportunityPassing play into the First Killer Double tapAtomic scores in the funniest bump almost won save off the post but went in 3-3Chronic gets a goal, the games getting messy, beast mode passes to opponentsGame 7:Tactical Timeout Used by NRGChronic get ANOTHER DUNK in the beginning, Ultimates take the leadNRG get a goal off kick off, right back to 1-1Crazy Beast Mode play, to beat 2 players and pass to Atomic for the GoalBoth teams Making more mistakes and going for it moreBeast mode hits a goal after messy defence from UltimatesChronic gets back to clear the line Ultimate get disorganized and don't manage to get any control back and lossWorld's Results Recap: https://liquipedia.net/rocketleague/Rocket_League_Championship_Series/2025Zodiak22 Too Much Space Chaos Maker Space BearFranc Awsomniss Digital Toast Yung slugSupport this podcast at — https://redcircle.com/asapweekly-rocket-league-podcast/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Ollie Basta, playing the lead role of podcaster/activist Jessie Keever, addresses a rally at the United Nations at the climax of ATOMIC BILL AND THE PAYMENT DUE This Week’s Two-Part Very Special Feature – The Peace Resource Center at Wilmington College and the Play, ATOMIC BILL AND THE PAYMENT DUE: Ollie Basta as podcaster/activist Jessie...

In this candid episode, Tom and Adam unpack the emotional rollercoaster of entrepreneurship and why so many business owners feel like they're always starting over. From podcast inspiration to coaching revelations, they discuss the importance of patience, trusting your intuition, and resisting the temptation to constantly compare your journey to others'. They also dive deep into the harsh truth: the grass often looks greener because it's been heavily fertilized — sometimes with a whole lot of crap.If you've ever struggled with staying the course, felt the pressure to pivot, or believed you should be further along, this episode will remind you why the long game matters, how to identify the right kind of fertilizer for your growth, and why building a successful business really does take a decade.

Send us a textThis week on Late to Grid, we sit down with Jon Krolewicz to dive into his incredible motorsports journey. He shares how a third-grade book report on the Indy 500 sparked a lifelong passion , and how a chance meeting with a pro driver his own size transformed his dream into a plan.Jon offers practical wisdom for anyone looking to get started or level up their game. He reveals the two biggest lessons he learned from karting: the importance of budgeting and how to harness your fear. Jon also talks about his "toy job" working at Firestone to fund his racing and a pivotal sponsorship story that taught him to think bigger.Beyond the track, Jon explains how his current role with the SCCA is focused on making racing more accessible, emphasizing that anyone can find their joy in the sport, whether it's behind the wheel or in the paddock.This episode is packed with stories and inspiration that prove it's never too late to chase your racing dream.Race season is here. If you need to catch up on setup, or have something that needs repaired, you need to be Atomic prepped. Get to https://atomicautosports.com/ to get your car ready to get out there next weekend. If you're chasing lap times, you need a track ready setup for your car. Get to AtomicAutosports.com to get your car scheduled to get you on the podium. Track ready setups for time trial drivers and others Thanks for listening and taking an interest in growing grassroots racing. The Late To Grid podcast shares the stories and inspiration that help listeners along their motorsports journey. Find all episodes on the Atomic Autosports website.

Send us a textWelcome to The Oncology Journal Club Podcast Series 3Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology NetworkWelcome to Episode 7 of The Oncology Journal Club podcast. This is where we take a famously different approach to oncology research.Join our expert hosts as they navigate the latest developments with their trademark blend of critical analysis, clinical wisdom and humour. With this in mind please note: Warning: This episode does contain some strong language.This week, Kate kicks us off with her report from the ESMO GI meeting with her key highlights.Craig sparks a fascinating discussion about robotic surgery.And CJ takes up a listener's suggestion and talks us through the ATOMIC study. And of course, we've also got our regular PBS Updates and Blow Your Own Trumpet papers.To learn more about The Oncology Network, subscribe to our free weekly Newsletter and listen to other fantastic podcasts, visit our website: www.oncologynetwork.com.au. You'll also find the Show Notes on the website with links to papers, a transcript and bios of our hosts.The Oncology Podcast - An Australian Oncology Perspective

Host Joe DeMare talks about a mushroom hunt in the Oak Openings Metropark where he found 17 different types of fungus, including an invasive Asian fungus. Next he interviews Libbe HaLevy, playwright and anti-nuclear activist about her new play "Atomic Bill and the Payment is Due," as well as her long running radio program, "Nuclear Hotseat." Rebecca Wood talks about AI, cryptocurrency, and Toledo Museum of Art Selling out real artists for computer generated ones. Ecological News includes more jellyfish attacks on nuke plants, states suing over Trump's closure of windfarms, and Energy Secretary Chris Wright's ridiculous tweets about wind and solar power.

In this conversation, Jungly discusses his work on P2Pool V2, a decentralized mining pool aimed at improving upon the limitations of the original P2Pool. He emphasizes the importance of decentralization in Bitcoin mining and explains the technical innovations that P2Pool V2 introduces, such as sharechains and atomic swaps for non-custodial payouts. Jungly also highlights the need for community involvement and developer engagement to ensure the project's success, and he shares his vision for a more accessible and efficient mining ecosystem.Takeaways:

Interview with Stephen G. Roman, President & CEO of Global Atomic Corp.Our previous interview: https://www.cruxinvestor.com/posts/global-atomic-tsxglo-advancing-uranium-production-in-niger-6089Recording date: 4th September 2025Global Atomic Corporation presents a compelling uranium investment opportunity at the intersection of critical supply shortages and surging demand from both traditional nuclear power and emerging artificial intelligence infrastructure. The company's flagship Dasa project in Niger represents Africa's highest-grade uranium deposit, positioned to address America's severe uranium supply deficit of 45-46 million pounds annually.The Dasa project's scale cannot be overstated. CEO Stephen Roman emphasizes that the deposit will produce as much as every uranium mine combined in the US, highlighting its strategic importance to American energy security. With US utilities currently burning 50 million pounds a year while domestic production reaches only four or five million pounds a year when fully ramped, Dasa directly addresses this critical supply gap.The project benefits from exceptional market timing. Microsoft's recent joining of the World Nuclear Association exemplifies the sector's transformation, as Roman notes: "Tech now is getting involved with nuclear because they know that's the only way to power data centers and their development." This new demand from AI and data center infrastructure compounds existing supply constraints in an already undersupplied uranium market.Global Atomic has achieved significant progress on long-awaited financing, securing term sheets from both the US Development Finance Corporation (DFC) and an Eastern joint venture partner. The company's preference for the DFC arrangement has received substantial political backing under the Trump administration, with Secretary of State Marco Rubio now chairing the DFC and businessman Benjamin Black as CEO.Roman confirms the project has been basically blessed by the White House, the State Department and various others in the administration, representing a dramatic shift in US government support. This backing extends beyond rhetoric, with America recently sending delegations to the Sahel region to build relationships and address security concerns, directly benefiting projects like Dasa.Despite financing delays, construction continues with 700 workers on-site and earthworks nearing completion by November 2025. The project has advanced to the third of five mining levels, with civil construction now underway. Production is scheduled for Q1 2027, placing Global Atomic among the rare near-term uranium producers in an undersupplied market.The company has already invested approximately $250 million, satisfying the DFC's 40% capital contribution requirement for their 60% loan facility. Current financing needs of $250-270 million have been reduced due to this prior investment, making the project more manageable for potential partners.Global Atomic has secured substantial revenue certainty through US utility offtake contracts representing 90% of production. This customer concentration supports both cash flow predictability and US strategic interests in uranium supply security.The investment opportunity is amplified by Niger's improved regulatory environment, with the new mineral code reducing royalties from 12% to 7% while maintaining favorable overall terms. The company's 97-98% local workforce employment strengthens government relations during regional political transitions.With share prices declining from $5 to $0.50 during geopolitical instability, patient investors may find significant value in a strategic asset approaching production in an fundamentally undersupplied uranium market driven by both traditional nuclear demand and emerging AI infrastructure requirements.View Global Atomic's company profile: https://www.cruxinvestor.com/companies/global-atomic-corpSign up for Crux Investor: https://cruxinvestor.com

In the decades since two modified B-29s dropped atomic bombs over Hiroshima and Nagasaki, Japan, bringing World War II to a close, there have been many ideas about how the power of the atom might be harnessed for other uses, including space exploration and aircraft propulsion.  On this episode, Aviation Week editors comb through our archives to discuss the legacy of the atomic bomb missions and the evolution of nuclear power in aerospace through to the present day—and beyond. “We hold in trust a power that is capable of unraveling the very fabric of our civilian…We have proved the destructive use, while the constructive applications are still in the realm of speculation.”-AW&ST, Sept. 1945 Check 6 Revisits delves into Aviation Week's more than 100-year archive. Subscribers can explore our archive here and read key Aviation Week articles related to this episode here: ‘Atomic' Aircraft Development Seen Far Off By Industry Heads (Aug. 13, 1945) Army-Navy Post-War Plane Needs Seen Large Despite Atomic Bomb (Aug. 20, 1945) The Atom | New Source of Energy; A Tide In The Affairs Of Men (September 1945) Atomic Transports 15-20 Years Away (Feb. 6, 1956) Nuclear Reactor Tests Include B-36 Flights (Jan. 16, 1956) The Soviet Nuclear-Powered Bomber (Dec. 1, 1958) Skunk Works Reveals Compact Fusion Reactor Details (Oct. 15, 2014) Debrief: Signs Of Life For Russia's Nuclear-Powered Cruise Missile (Aug. 18, 2025)

Send us a textIn this episode of the Life Science Success Podcast my guest is Mark Stead, Head of Business Development at Atomic AI, a pioneering biotech company using artificial intelligence and structural biology to develop innovative RNA-targeted therapeutics. Mark brings over 12 years of experience in biotechnology, with a proven track record of negotiating high-value partnerships and driving strategic collaborations in drug discovery.00:00 Introduction to the Life Science Success Podcast00:30 Meet Mark Stead: Journey into Life Sciences03:26 Career Insights: From Amgen to Atomic AI11:20 Innovations at Atomic AI: Leveraging AI and Structural Biology19:37 The Future of AI in Drug Discovery31:03 Leadership and Personal Insights39:38 Conclusion and Farewell

Yonatan Sompolinsky is an academic in the field of computer science, best known for his work on the GHOST protocol (Greedy Heaviest Observed Subtree, which was cited in the Ethereum whitepaper) and the way he applied his research to create Kaspa. In this episode, we talk about scaling Proof of Work and why Kaspa might be a worthy contender to process global payments. –––––––––––––––––––––––––––––––––––– Time stamps: 00:01:22 - Debunking rumors: Why some think Yonatan is Satoshi Nakamoto 00:02:52 - Candidates for Satoshi: Charles Hoskinson, Charlie Lee, Zooko, and Alex Chepurnoy 00:03:41 - Alex Chepurnoy as a Satoshi-like figure 00:04:07 - Kaspa overview: DAG structure, no orphaned blocks, generalization of Bitcoin 00:04:55 - Similarities between Kaspa and Bitcoin fundamentals 00:06:12 - Why Kaspa couldn't be built directly on Bitcoin 00:08:05 - Kaspa as generalization of Nakamoto consensus 00:11:55 - Origins of GHOST protocol and early DAG concepts for Bitcoin scaling 00:13:16 - Academic motivation for GHOST and transitioning to computer science 00:13:50 - Turtle pet named Bitcoin 00:15:22 - Increasing block rate in Bitcoin and GHOST protocol 00:16:57 - Meeting Gregory Maxwell and discovering GHOST flaws 00:20:00 - Yonatan's views on drivechains and Bitcoin maximalism 00:20:36 - Defining Bitcoin maximalism: Capital B vs lowercase b 00:23:18 - Satoshi's support for Namecoin and merged mining 00:24:12 - Bitcoin culture in 2013-2018: Opposing other functionalities 00:26:01 - Vitalik's 2014 article on Bitcoin maximalism 00:26:13 - Andrew Poelstra's opposition to other assets on Bitcoin 00:26:38 - Bitcoin culture: Distaste for DeFi, criticism of Ethereum as a scam 00:28:03 - Bitcoin Cash developments: Cash tokens, cash fusion, contracts 00:28:39 - Rejection of Ethereum in Bitcoin circles 00:30:18 - Ethereum's successful PoS transition despite critics 00:35:04 - Ethereum's innovation: From Plasma to ZK rollups, nurturing development 00:37:04 - Stacks protocol and criticism from Luke Dashjr 00:39:02 - Bitcoin culture justifying technical limitations 00:41:01 - Declining Bitcoin adoption as money, rise of altcoins for payments 00:43:02 - Kaspa's aspirations: Merging sound money with DeFi, beyond just payments 00:43:56 - Possibility of tokenized Bitcoin on Kaspa 00:46:30 - Native currency advantage and friction in bridges 00:48:49 - WBTC on Ethereum scale vs Bitcoin L2s 00:53:33 - Quotes: Richard Dawkins on atheism, Milton Friedman on Yap Island money 00:55:44 - Story of Kaspa's messy fair launch in 2021 01:14:08 - Tech demo of Kaspa wallet experience 01:28:45 - Kaspa confirmation times & transaction fees 01:43:26 - GHOST DAG visualizer 01:44:10 - Mining Kaspa 01:55:48 - Data pruning in Kaspa, DAG vs MimbleWimble 02:01:40 - Grin & the fairest launch 02:12:21 - Zcash scaling & ZKP OP code in Kaspa 02:19:50 - Jameson Lopp, cold storage & self custody elitism 02:35:08 - Social recovery 02:41:00 - Amir Taaki, DarkFi & DAO 02:53:10 - Nick Szabo's God Protocols 03:00:00 - Layer twos on Kaspa for DeFi 03:13:09 - How Kaspa's DeFi will resemble Solana 03:24:03 - Centralized exchanges vs DeFi 03:32:05 - The importance of community projects 03:37:00 - DAG KNIGHT and its resilience 03:51:00 - DAG KNIGHT tradeoffs 03:58:18 - Blockchain vs DAG, the bottleneck for Kaspa 04:03:00 - 100 blocks per second? 04:11:43 - Question from Quai's Dr. K 04:17:03 - Doesn't Kaspa require super fast internet? 04:23:10 - Are ASIC miners desirable? 04:33:53 - Why Proof of Work matters 04:35:55 - A short history of Bitcoin mining 04:44:00 - DAG's sequencing 04:49:09 - Phantom GHOST DAG 04:52:47 - Why Kaspa had high inflation initially 04:55:10 - Selfish mining 05:03:00 - K Heavy Hash & other community questions 06:33:20 - Latency settings in DAG KNIGHT for security 06:36:52 - Aviv Zohar's involvement in Kaspa research 06:38:07 - World priced in Kaspa after hyperinflation 06:39:51 - Kaspa's fate intertwined with crypto 06:40:29 - Kaspa contracts vs Solana, why better for banks 06:42:53 - Cohesive developer experience in Kaspa like Solana 06:45:22 - Incorporating ZK design in Kaspa smart contracts 06:47:22 - Heroes: Garry Kasparov 06:48:12 - Shift in attitude from academics like Hoskinson, Buterin, Back 06:53:07 - Adam Back's criticism of Kaspa 06:55:57 - Michael Jordan and LeBron analogy for Bitcoiners' mindset 06:58:02 - Can Kaspa flip Bitcoin in market cap 07:00:34 - Gold and USD market cap comparison 07:06:06 - Collaboration with Kai team 07:10:37 - Community improvement: More context on crypto 07:13:43 - Theoretical maximum TPS for Kaspa 07:16:05 - Full ZK on L1 improvements 07:17:45 - Atomic composability and logic zones in Kaspa 07:23:12 - Sparkle and monolithic UX feel 07:26:00 - Wrapping up: Beating podcast length record, final thoughts on Bitcoin and Kaspa 07:27:31 - Why Yonatan called a scammer despite explanations 07:32:29 - Luke Dashjr's views and disconnect 07:33:01 - Hope for Bitcoin scaling and revolution

3pm: I Was Thinking: Atomic Wedgies and Communism // This Day in History: 1776 - British forces defeat Patriots in the Battle of Brooklyn // Father abandons child on Pierce County freeway for being ‘loud and disruptive’

It's a bumper, star-studded week for guests with two glorious duos discussing their shows - Hostage and Atomic, while we're still missing our leader James so it's another “Dot and Ethel” two hander with Boyd, live from the Edinburgh TV festival, and Kay, live from her living room. They review the aforementioned Atomic on Sky, plus King & Conqueror and season 3 of invasion. Yes, season 3. But all the other brand new shows are embargoed.

It's the 80th anniversary of the dropping of the atomic bombs on Hiroshima and Nagasaki. The Bulletin of Atomic Scientists has the Doomsday Clock at 89 seconds to midnight, while Trump moves nuclear submarines closer to Russia in response to social media posts by Russian officials. Aerial photographs of the Gaza Strip look eerily similar to Hiroshima and Nagasaki 80 years ago. It's a good a time as ever to consider and re-consider the lessons of Truman's "Atomic Diplomacy" in 1945. So we're reposting our episode on the atomic bombing of Japan at the end of World War Two. -----------------------------------------From the 2020 episode: “For years, large majorities of Americans have believed that the U.S. had to use the A-Bomb against Japan on August 6th, 1945 to end the war quickly and avoid a land war and thus save one-million American lives. Scott and Bob discuss the use of the bomb, why it was used as a message to the Soviet Union and not a military necessity, the chronology behind the development and deployment of atomic weapons, the U.S. public response to it, and the creation of a new history, a propaganda piece, regarding the use of the bomb. The dropping of the bomb on Hiroshima was vital in the development of the Cold War, the arms race, the military-industrial complex, and the National Security State. Seventy-five years after the first atomic weapon was used by the U.S., it's still a highly-debated and important topic.”------------------------------------Outro- Green and Red Blues by Moody

Peter Van Doren and David Kemp bring libertarian skepticism to the bipartisan political support for nuclear power. They analyze why regulatory reform alone may not solve nuclear's economic problems and discuss how recent U.S. projects have failed to deliver on promises of cost-effectiveness even after a supposed "renaissance" in the late 2000s. They finish up with a discussion on whether small modular reactors (SMRs) are the nuclear silver bullet.Show Notes:Peter Van Doren and David Kemp, Nuclear Power in the Context of Climate Change, Cato Institute Working Paper, April 27, 2023. https://www.cato.org/working-paper/nuclear-power-context-climate-change.David Kemp and Peter Van Doren, "Would a Carbon Tax Rejuvenate Nuclear Energy?" Regulation 45, no. 3 (Fall 2022). https://www.cato.org/regulation/fall-2022/would-carbon-tax-rejuvenate-nuclear-energy.David Kemp, "Nuclear Power's Newest Cautionary Tale," Cato at Liberty (blog), January 23, 2024. https://www.cato.org/blog/nuclear-powers-newest-cautionary-tale. Hosted on Acast. See acast.com/privacy for more information.

Protect Your Retirement W/ a PHYSICAL Gold IRA https://www.sgtreportgold.com/ CALL( 877) 646-5347 - Noble Gold is Who I Trust   In the United States we are ALL being bombarded by dangerous EMF radiation on a daily basis. The negative biological effects CAN include: Fatigue, sleep disturbances, concentration difficulties, headaches, immune system imbalances, cancer, evidence for Alzheimer's disease, lower sperm count, other reproductive issues & much more. Find out HOW to prevent radiation poisoning and abate these serious health risks and in this discussion with Cory Hillis, President of EMF Solutions. Thanks for tuning in!   EMF SOLUTIONS: https://www.emfsol.com/?aff=SGTreport The ONLY products proven to normalize the effect of EMF radiation on human cells!   RELATED: Bioinitiative2012 https://bioinitiative.org/conclusions/ https://rumble.com/embed/v6utmc2/?pub=2peuz