Podcasts about Vertex Pharmaceuticals

Learn why culture and constant innovation are essential to developing life-changing biopharma treatments. Vertex Pharmaceuticals focuses on “serial innovation” because this year's billion-dollar blockbuster drug could become next year's failure. How does this biopharmaceutical company recruit and onboard employees, and how does it create a culture where the best ideas thrive? Join David Young and guest Reshma Kewalramani, president and CEO at Vertex Pharmaceuticals and a recipient of the 2025 CED Distinguished Leadership Awards. You'll learn about Kewalramani's career path, what the company learned from developing a hepatitis C drug, and why the company welcomes in students to experiment alongside employees. The Leadership in Challenging Times discussions feature timely and insightful discussions with the outstanding CEOs who are recipients of CED's Distinguished Leadership Awards. Business leader honorees discuss the unprecedented challenges facing the nation and how they are helping chart a path forward for both their companies and communities in which they operate. For more from The Conference Board: ·         CED Announces Recipients of Its 2025 Distinguished Leadership Awards ·         CED Distinguished Leadership Awards Celebration ·         Women in STEM: Closing the Gender Gap

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: loads of news from American Diabetes Association Scientific Sessions, GLP1 for T1D, Tech updates, diabetes in space, and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Top story – looking back at The American Diabetes Association Scientific Sessions conference. I won't recap everything here – but I'll link up to a few more comprehensive article. Here's just a taste! XX A single infusion of a new stem cell-based treatment helped 10 out of 12 people with severe type 1 diabetes stop using insulin, researchers report. The treatment, called zimislecel, was made by Vertex Pharmaceuticals. It's an infusion of lab-grown islet cells. A year after getting the therapy, 10 patients no longer needed insulin shots. The other two were able to reduce how much insulin they needed.  The treatment requires patients to take immunosuppressive drugs, which may raise the risk of infections or cancer in the long run, experts said. https://www.usnews.com/news/health-news/articles/2025-06-24/stem-cell-treatment-may-free-some-with-type-1-diabetes-from-insulin XX New study shows inhaled insulin is safe and effective for children with type 1 diabetes. This is Mannkind's Afrezza, which takes the place of rapid-acting mealtime insulin. Findings indicate that inhaled insulin delivers glycemic control comparable to injected rapid-acting insulin. Inhaled insulin was also associated with less weight gain and slightly higher patient and parent preference scores. These findings add to outcomes shared from INHALE 1 late last year. Based on the findings of the inhaled insulin study, MannKind looks to seek FDA approval to expand Afrezza's indication to children. The company also aims to evaluate inhaled insulin at diagnosis and in automated insulin delivery systems in additional studies. https://www.drugdeliverybusiness.com/study-mannkind-inhaled-insulin-safe-effective-children/ XX Positive outcomes in two different studies looking at GLP 1 medications for type 1. Semaglutide – brand name Ozempic or Wegovy - reduced glucose levels and weight among patients with type 1 diabetes and obesity. 26-week, double-blind trial of 72 adults, those taking Ozempic spent More than 70% time spent in sensor glucose range (70-180 mg/dL) Less than 4% time spent in hypoglycemia (

Broadcast from KSQD, Santa Cruz on 6-26-2025: Dr. Dawn opens with groundbreaking results from Vertex Pharmaceuticals' stem cell treatment for severe type 1 diabetes. The experimental therapy, Zimislecel, converts stem cells into pancreatic islet cells and infuses them into patients. In a 12-person study, 10 patients no longer need insulin after one year. The cells migrated to the liver and began producing insulin in response to glucose levels. Patients with hypoglycemic unawareness saw complete elimination of dangerous episodes after three months. However, patients must take lifelong immunosuppressive drugs to prevent rejection. The research represents 25 years of work by Harvard's Doug Melton. A caller asks about Keytruda treatment for melanoma. Dr. Dawn explains it's an immunotherapy drug targeting programmed death receptors that cancer cells hijack to evade immune response. The drug can cause serious immune overreactions but is standard for metastatic melanoma. Treatment protocols depend on cancer staging. For young patients with decades to lose, aggressive treatment is often justified despite risks. An email about morning arthritis pain leads to chronotherapy research discussion. Macrophages have energy levels that peak in the morning when inflammasome activation is quicker and more robust, explaining why arthritis pain is worst after overnight rest. Treatment timing could optimize anti-inflammatory medications by taking them at bedtime. Another email about eye irritation prompts diagnostic discussion. Dr. Dawn recommends examining for bacterial blepharitis before assuming food allergies and testing antihistamine drops. For elimination diets, common allergens include wheat, dairy, corn, soy, and peanuts. However, without other symptoms, food allergies are unlikely causes of isolated eye problems. Dr. Dawn explores advancing CAR-T cell therapy using RNA technology. Traditional therapy costs up to $500,000 per patient requiring lab reprogramming. New RNA-containing nanoparticles temporarily create antigen receptors for about one week. Mouse studies eliminated detectable tumors at highest doses. While effects are temporary, this could dramatically reduce costs and complexity. She discusses DNA forensics evolution from O.J. trial era to current technologies. New paleogenomics technology can analyze fragmented DNA from hair, previously considered unusable. Mitochondrial DNA analysis can definitively exonerate suspects. This led to Charles Fane's release after 17 years on death row when hair evidence proved innocence and identified the actual perpetrator. Dr. Dawn introduces Barrett's esophagus screening replacing invasive endoscopy. Patients swallow a capsule containing a compressed sponge that expands in the stomach and is pulled out via string, collecting esophageal cells. The test identifies abnormalities with 100-fold increased cancer risk when positive and 98% accuracy when negative, allowing targeted endoscopy only for high-risk patients. She concludes discussing body composition analysis superiority over BMI. Studies found overweight BMI showed 3.6 times higher heart disease risk, while large waist circumference showed four times higher risk. However, BMI had no significant relationship with overall mortality. Dr. Dawn advocates for bioimpedance analysis devices to measure body fat percentage and track muscle loss.

Broadcast from KSQD, Santa Cruz on 6-26-2025: Dr. Dawn opens with groundbreaking results from Vertex Pharmaceuticals' stem cell treatment for severe type 1 diabetes. The experimental therapy, Zimislecel, converts stem cells into pancreatic islet cells and infuses them into patients. In a 12-person study, 10 patients no longer need insulin after one year. The cells migrated to the liver and began producing insulin in response to glucose levels. Patients with hypoglycemic unawareness saw complete elimination of dangerous episodes after three months. However, patients must take lifelong immunosuppressive drugs to prevent rejection. The research represents 25 years of work by Harvard's Doug Melton. A caller asks about Keytruda treatment for melanoma. Dr. Dawn explains it's an immunotherapy drug targeting programmed death receptors that cancer cells hijack to evade immune response. The drug can cause serious immune overreactions but is standard for metastatic melanoma. Treatment protocols depend on cancer staging. For young patients with decades to lose, aggressive treatment is often justified despite risks. An email about morning arthritis pain leads to chronotherapy research discussion. Macrophages have energy levels that peak in the morning when inflammasome activation is quicker and more robust, explaining why arthritis pain is worst after overnight rest. Treatment timing could optimize anti-inflammatory medications by taking them at bedtime. Another email about eye irritation prompts diagnostic discussion. Dr. Dawn recommends examining for bacterial blepharitis before assuming food allergies and testing antihistamine drops. For elimination diets, common allergens include wheat, dairy, corn, soy, and peanuts. However, without other symptoms, food allergies are unlikely causes of isolated eye problems. Dr. Dawn explores advancing CAR-T cell therapy using RNA technology. Traditional therapy costs up to $500,000 per patient requiring lab reprogramming. New RNA-containing nanoparticles temporarily create antigen receptors for about one week. Mouse studies eliminated detectable tumors at highest doses. While effects are temporary, this could dramatically reduce costs and complexity. She discusses DNA forensics evolution from O.J. trial era to current technologies. New paleogenomics technology can analyze fragmented DNA from hair, previously considered unusable. Mitochondrial DNA analysis can definitively exonerate suspects. This led to Charles Fane's release after 17 years on death row when hair evidence proved innocence and identified the actual perpetrator. Dr. Dawn introduces Barrett's esophagus screening replacing invasive endoscopy. Patients swallow a capsule containing a compressed sponge that expands in the stomach and is pulled out via string, collecting esophageal cells. The test identifies abnormalities with 100-fold increased cancer risk when positive and 98% accuracy when negative, allowing targeted endoscopy only for high-risk patients. She concludes discussing body composition analysis superiority over BMI. Studies found overweight BMI showed 3.6 times higher heart disease risk, while large waist circumference showed four times higher risk. However, BMI had no significant relationship with overall mortality. Dr. Dawn advocates for bioimpedance analysis devices to measure body fat percentage and track muscle loss.

Neil Haley welcomes Hall of Fame basketball legend Alonzo Mourning and LaVarne Addison Burton, CEO of the American Kidney Fund (AKF), to discuss APOL1-mediated kidney disease (AMKD). Alonzo shares his personal experience with kidney disease, emphasizing the importance of early detection, proactive healthcare, genetic testing, and open communication with doctors—especially for people of color, who are at a higher risk for AMKD.1. Understanding AMKD:APOL1-mediated kidney disease is caused by specific genetic mutations in the APOL1 gene.Higher risk among individuals with African, Afro-Caribbean, Latino/Latina, and Black American heritage.2. Alonzo Mourning's Personal Story:Diagnosed following abnormal blood tests and fatigue during the 2000 Olympics.Initial symptoms included swelling in legs and fatigue.Eventually diagnosed with focal segmental glomerulosclerosis (FSGS), a form of AMKD.Received a kidney transplant in 2003, returned to professional basketball, and won an NBA championship in 2006.3. Importance of Early Detection:Recognizing and not ignoring symptoms can prevent or delay kidney failure.Encourages listeners to be proactive and visit doctors regularly.4. Genetic Testing and Medical Care:Genetic testing is crucial to identifying AMKD.Encourages seeking multiple medical opinions for accurate diagnosis and effective care.5. Addressing Medical Mistrust:Alonzo highlights the historical mistrust of healthcare in communities of color.Emphasizes importance of overcoming this mistrust to ensure proper care.6. Awareness Initiatives:Second annual AMKD Awareness Day observed on April 29th.AKF providing comprehensive resources and education via their website.“Health is wealth. If you don't have your health, you don't have anything.” – Alonzo Mourning“Early detection can significantly improve outcomes and slow disease progression.” – LaVarne Addison BurtonAmerican Kidney Fund Website: kidneyfund.org/amkdEmpower Forward Website: empowerforwardtogether.comAlonzo Mourning: Hall of Fame Basketball Player, Spokesperson for Vertex Pharmaceuticals.LaVarne Addison Burton: President and CEO, American Kidney Fund.Key Discussion Points:Memorable Quotes:Resources and Information:Connect with Alonzo Mourning and AKF:

Damian Sanchez, (Damian J to music fans) is a Miami-based jazz musician. A car accident landed him in the hospital with multiple fractures to his leg. Once there, he faced the difficult decision of whether or not to take the pain medication that was offered to him. With patients like Damian in mind, Dr. Paul Negulescu and the research team at Vertex are thinking differently about pain – they’re investigating potential non-opioid based treatment options that aim to target pain differently. This episode of Targeting the Toughest Diseases is sponsored by Vertex Pharmaceuticals.See omnystudio.com/listener for privacy information.

In der heutigen Folge von „Alles auf Aktien“ sprechen die Finanzjournalisten Anja Ettel und Daniel Eckert über die Magie der Mausaktie Disney, Insolvenz einer Diät-Ikone und den stoischen Kurs der Fed. Außerdem geht es um Alphabet, Nvidia, Uber, Charles River Laboratories, Hensoldt, Fresenius, Vonovia, Carl Zeiss Meditec, Eli Lilly, Novo Nordisk, WeightWatchers, Volkswagen, Mercedes, BMW, Ferrari, Nvidia, Meta Platforms, Microsoft, Altria, Saudi-Aramco, AppLovin, ConocoPhillips, CNOOC, Investor AB, Arista Networks, Visa, Blackstone, KKR, Pinduoduo, Investor AB, Hermès, Münchener Rück, Allianz, Deutsche Telekom, SAP, MicroStrategy und Vertex Pharmaceuticals. Wir freuen uns an Feedback über aaa@welt.de. Ab sofort gibt es noch mehr "Alles auf Aktien" bei WELTplus und Apple Podcasts – inklusive aller Artikel der Hosts und AAA-Newsletter.[ Hier bei WELT.](https://www.welt.de/podcasts/alles-auf-aktien/plus247399208/Boersen-Podcast-AAA-Bonus-Folgen-Jede-Woche-noch-mehr-Antworten-auf-Eure-Boersen-Fragen.html) [Hier] (https://open.spotify.com/playlist/6zxjyJpTMunyYCY6F7vHK1?si=8f6cTnkEQnmSrlMU8Vo6uQ) findest Du die Samstagsfolgen Klassiker-Playlist auf Spotify! Disclaimer: Die im Podcast besprochenen Aktien und Fonds stellen keine spezifischen Kauf- oder Anlage-Empfehlungen dar. Die Moderatoren und der Verlag haften nicht für etwaige Verluste, die aufgrund der Umsetzung der Gedanken oder Ideen entstehen. Hörtipps: Für alle, die noch mehr wissen wollen: Holger Zschäpitz können Sie jede Woche im Finanz- und Wirtschaftspodcast "Deffner&Zschäpitz" hören. Außerdem bei WELT: Im werktäglichen Podcast „Das bringt der Tag“ geben wir Ihnen im Gespräch mit WELT-Experten die wichtigsten Hintergrundinformationen zu einem politischen Top-Thema des Tages. +++ Werbung +++ Du möchtest mehr über unsere Werbepartner erfahren? [**Hier findest du alle Infos & Rabatte!**](https://linktr.ee/alles_auf_aktien) Impressum: https://www.welt.de/services/article7893735/Impressum.html Datenschutz: https://www.welt.de/services/article157550705/Datenschutzerklaerung-WELT-DIGITAL.html

Market volatility is starting to decrease, and markets are returning to a more normal state. The short-term picture is slowly moving into overbought territory, while both the medium- and long-term outlooks are still flashing strong buy signals.On Wednesday, the Fed and Chair Powell will announce the interest rate decision, with markets widely anticipating no change.Throughout the week, several high-profile companies will report their quarterly results, including Palantir, AMD, Vertex Pharmaceuticals, Disney, Uber, Shopify, and others.All this and more in this week's "Trading Tips With Jim."#StockMarket #MarketUpdate #TradingTips #Investing #StockAnalysis #Palantir #AMD #VertexPharmaceuticals #Disney #Uber #Shopify #EarningsSeason #FederalReserve #Powell #InterestRates #BuySignals #MarketOutlook

In this episode, Mark Longo, Henry Schwartz (Cboe) and Mike Tosaw (St. Charles Wealth Management) hosts delve into current market trends, unusual options activity, and listener questions. They discuss VIX movement, the resurgence of gold, and controversial trades ahead of the tariff announcement. New options products, such as the S&P Equal Weighted 500 Index options, are introduced, and there's an examination of activity in Vertex Pharmaceuticals, NeoGenomics, Eldorado Gold Corp, and Dynatrace. The hosts also review audience poll results on zero-day options trading and the viability of certain puts in Apple and Nvidia. 00:00 Introduction to Options Insider Radio Network 01:18 Meet the Hosts and Sponsors 03:16 Market Overview and Trading Block 05:41 Volatility and Market Trends 13:13 Gold and Precious Metals Discussion 15:43 Options Market Activity 30:55 Unusual Options Activity in Vertex Pharmaceuticals 33:48 Biotech and Option Flow Insights 34:51 NeoGenomics Inc: A Rough Year 37:21 Gold's Impressive Run 43:13 Dynatrace Inc: Tech Observability 47:01 Mail Block: Listener Questions 57:56 Around the Block: Market Watch  

In this episode, Mark Longo, Henry Schwartz (Cboe) and Mike Tosaw (St. Charles Wealth Management) hosts delve into current market trends, unusual options activity, and listener questions. They discuss VIX movement, the resurgence of gold, and controversial trades ahead of the tariff announcement. New options products, such as the S&P Equal Weighted 500 Index options, are introduced, and there's an examination of activity in Vertex Pharmaceuticals, NeoGenomics, Eldorado Gold Corp, and Dynatrace. The hosts also review audience poll results on zero-day options trading and the viability of certain puts in Apple and Nvidia. 00:00 Introduction to Options Insider Radio Network 01:18 Meet the Hosts and Sponsors 03:16 Market Overview and Trading Block 05:41 Volatility and Market Trends 13:13 Gold and Precious Metals Discussion 15:43 Options Market Activity 30:55 Unusual Options Activity in Vertex Pharmaceuticals 33:48 Biotech and Option Flow Insights 34:51 NeoGenomics Inc: A Rough Year 37:21 Gold's Impressive Run 43:13 Dynatrace Inc: Tech Observability 47:01 Mail Block: Listener Questions 57:56 Around the Block: Market Watch  

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD information, and to apply for credit, please visit us at PeerView.com/YKX865. CME/NCPD credit will be available until April 18, 2026.Innovation Takes Shape in SCD: Rewriting Management Principles With Gene Therapy and Revisiting the Role of HCT In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Vertex Pharmaceuticals.Disclosure information is available at the beginning of the video presentation.

Think you're just a boss? Nah, you could be a mentor—and it might just change your team, your career, and even your bottom line. Let's unpack why, with some important stats, real stories, and takeaways you can use tomorrow. Let's take a look. First off, mentoring isn't just warm fuzzies—it's can be a game-changer for all those involved. Research says mentees get promoted five times more often than those without mentors, and retention jumps by 22%. That's from McCarthy Mentoring's 2017 study, and it's not just relevant, but growing in importance in in 2025. Imagine keeping your best people longer and seeing them climb the ladder—all because you took time to guide them. That's power! Here in Australia, COX Architecture saw this firsthand. After growing fast, their Sydney team—500 strong—used mentoring to tighten bonds and set sharper goals. Staff started to redefine and focus on their career paths, and the resulting morale? Unbeatable. Check it out on Parlour's site if you're curious. I'll include the links on the blog I've connected to this podcast. Now, let's talk diversity. Mentoring lifts everyone. Cornell University found it boosts minority leadership roles by up to 24%. In Aussie terms, look at the Australian Business and Community Network—ABCN. They went digital with Accenture in 2020, mentoring disadvantaged kids, including Indigenous communities. Result? 42% felt more confident about their future. That's not just feel-good—it's building a pipeline of diverse talent. As a manager, you could do that too! Okay, here's a stat to chew on: 71% of Fortune 500 companies run mentoring programs. It's not a trend—it's a standard. Down under, AusIMM's 2024 program hooked up over 100 mining pros. Mentors reported a 20% jump in job satisfaction—proof you don't just help others, you grow too. And get this: Cox Automotive saved over $3 million in turnover costs since 2017 with mentoring. That's cash you could keep in your budget! So, real-world wins? Plenty. Avison Young pushed women into leadership with mentoring—diversity ticked up fast. Vertex Pharmaceuticals went global, mixing reverse mentoring with peer circles—genius for multigenerational teams. And Paychex? Their high-potential women hit 94% retention. These aren't flukes; they're proof mentoring works. Locally, ABCN's online shift delivered 179 sessions in a year—regional kids got a leg up. That's mentoring breaking barriers, right here in Oz. Takeaways time! One: mentoring keeps talent and cuts costs—think millions, not pennies. Two: it's your diversity secret weapon—lift up underrepresented voices. Three: you'll grow as a leader—satisfaction and skills, sorted. How do you start? Assess your team's needs, pair people smartly, and track the wins—engagement, retention, you name it.

Fund your account in five minutes or less at https://www.public.com/CSI and get up to $10,000 when you transfer your old portfolio. Join us on Discord with Semiconductor Insider: https://ko-fi.com/chipstockinvestor/tiersIn this episode of Chip Stock Investor, Kasey discusses Vertex Pharmaceuticals which was a recent addition to the Chip Stock Investor portfolio. Vertex had two new approvals before the most recent earnings report with more to come in the coming years. Will 2025 be a breakout year for Vertex?Supercharge your analysis with AI! Get 15% of your membership with our special link here: https://finchat.io/csi/Affiliate links that are sprinkled in throughout this video. If something catches your eye and you decide to buy it, we might earn a little coffee money. Thanks for helping us (Kasey) fuel our caffeine addiction!Content in this video is for general information or entertainment only and is not specific or individual investment advice. Forecasts and information presented may not develop as predicted and there is no guarantee any strategies presented will be successful. All investing involves risk, and you could lose some or all of your principal. #vertexstock #vrtx #newpainmedication #pharmastocks #healthcarestocks #semiconductors #chips #investing #stocks #finance #financeeducation #financeeducation #finance #stocks #investing #investor #financeeducation #stockmarket #chipstockinvestor #semiconductorstocks Nick and Kasey own shares of Vertex PharmaceuticalsPublic Disclosure:All investing involves the risk of loss, including loss of principal. Brokerage services for US-listed, registered securities, options and bonds in a self-directed account are offered by Public Investing, Inc., member FINRA & SIPC. Public Investing offers a High-Yield Cash Account where funds from this account are automatically deposited into partner banks where they earn interest and are eligible for FDIC insurance; Public Investing is not a bank. Cryptocurrency trading services are offered by Bakkt Crypto Solutions, LLC (NMLS ID 1890144), which is licensed to engage in virtual currency business activity by the NYSDFS. Cryptocurrency is highly speculative, involves a high degree of risk, and has the potential for loss of the entire amount of an investment. Cryptocurrency holdings are not protected by the FDIC or SIPC. A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. The 6%+ yield is the average, annualized yield to worst (YTW) across all ten bonds in the Bond Account, before fees, as of 12/13/2024. A bond's yield is a function of its market price, which can fluctuate; therefore, a bond's YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See Bond Account Disclosures to learn more.Alpha is an AI research tool powered by GPT-4. Alpha is experimental and may generate inaccurate responses. Output from Alpha should not be construed as investment research or recommendations, and should not serve as the basis for any investment decision. Public makes no warranties about its accuracy, completeness, quality, or timeliness of any Alpha out. Please independently evaluate and verify any such output for your own use case.*Terms and Conditions apply.

It's the first FDA approval for a pain medication in 25 years. How does the drug work, and who is it for? Also, non-mixing layers of water and hydrocarbons thousands of miles deep could explain the icy planets' strange magnetic fields.The FDA Approves A New, Non-Opioid PainkillerIn January, the Food and Drug Administration approved a new pain medicine called Journavx (suzetrigine), made by Vertex Pharmaceuticals. It's the first time in 25 years the agency has given the green light to a new painkiller. Notably, it's not an opioid and, according to the company, it's not addictive. Unlike opioids, which act directly on the brain, Journavx instead blocks nerve endings across the body that transmit pain.Host Ira Flatow is joined by Dr. Sean Mackey, a professor of anaesthesiology and pain medicine at Stanford University and chief of the Division of Stanford Pain Medicine, to discuss how the new drug works, who should take it, and what its limitations are.Might Uranus And Neptune Have Deep, Multi-Layer Oceans?We've got a pretty good idea about what's beneath the surface of our nearest planetary neighbors, like Mars. But as you get farther out into the solar system, our knowledge becomes scarce. For instance, what's inside the so-called ice giants, Neptune and Uranus?Recent research based on computer simulations of fluids hints that the planets could contain vast multi-layered oceans, as much as thousands of miles deep. A layer of water that is on top of—but doesn't mix with—a deeper layer of hydrocarbons could help explain strange magnetic fields observed during the Voyager mission.Dr. Burkhardt Militzer, a professor of earth and planetary sciences at UC Berkeley, wrote about this idea in the Proceedings of the National Academy of Sciences. He joins Host Ira Flatow to explain his theories.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Moderate—but not excessive—exercise can curb appetite; When you're older does your ability to absorb supplements decline? FDA warns against eye drop to change eye color; Are soy supplements safe for breast cancer patients? Most ditch GLP-1 drugs after one year; Some B-complex supplements don't deliver full suite of B vitamins; Novel non-addictive pain drug approved; Why mosquitoes can bite in mid-winter; Oops—surgeon removes patient's liver, mistaking it for spleen. 

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.## Pfizer announces positive results for COVID-19 vaccinePfizer has recently announced positive results from their phase 3 clinical trial for their COVID-19 vaccine. The vaccine showed over 90% effectiveness in preventing COVID-19 in participants. This is a promising development in the fight against the pandemic.## Moderna seeking emergency use authorization for COVID-19 vaccineModerna is seeking emergency use authorization from the FDA for their COVID-19 vaccine. The vaccine has shown promising results in clinical trials and could be available to the public soon. This is another step forward in the race to develop a safe and effective vaccine against COVID-19. ## AstraZeneca facing challenges with COVID-19 vaccine trialAstraZeneca has faced challenges with their COVID-19 vaccine trial, as some participants experienced adverse reactions. The company has paused the trial to investigate these reactions and ensure the safety of the vaccine. This highlights the importance of rigorous testing and monitoring in vaccine development.## Johnson & Johnson pauses COVID-19 vaccine trialJohnson & Johnson has also paused their COVID-19 vaccine trial due to an unexplained illness in a participant. The company is investigating the illness to determine if it is related to the vaccine. This pause emphasizes the need for thorough safety monitoring in clinical trials.## Roche launches rapid antigen test for COVID-19Roche has launched a rapid antigen test for COVID-19 that provides results in just 15 minutes. The test is designed for use in point-of-care settings and can help quickly identify individuals infected with the virus. This could be a valuable tool in controlling the spread of COVID-19.## Novartis acquires Vedere BioNovartis has acquired Vedere Bio, a company focused on developing gene therapies for vision loss. This acquisition expands Novartis' capabilities in gene therapy and strengthens their position in the ophthalmology market. It also demonstrates Novartis' commitment to advancing innovative treatments for patients with vision disorders.## Gilead Sciences receives FDA approval for TrodelvyGilead Sciences has received FDA approval for Trodelvy, a treatment for metastatic triple-negative breast cancer. Trodelvy has shown promising results in clinical trials and provides a new treatment option for patients with this aggressive form of breast cancer. This approval represents an important milestone in the fight against breast cancer.## Vertex Pharmaceuticals acquires Semma TherapeuticsVertex Pharmaceuticals has acquired Semma Therapeutics, a company focused on developing cell-based therapies for diabetes. This acquisition enhances Vertex's pipeline in regenerative medicine and strengthens their commitment to finding a cure for diabetes. It also highlights the growing interest in cell therapy as a treatment approach for chronic diseases.## Eli Lilly announces positive results for Alzheimer's drugEli Lilly has announced positive results from their phase 2 clinical trial for an Alzheimer's drug targeting amyloid plaques in the brain. The drug showed a significant reduction in amyloid levels compared to placebo, indicating potential disease-modifying effects. This is a hopeful development in the search for effective treatments for Alzheimer's disease.## Amgen launches biosimilar of AvastinAmgen has launched a biosimilar of Avastin, a widely used cancer drug that targets blood vessel growth in tumors. The biosimilar, known as Mvasi, offers a more affordable alternative to Avastin while maintaining similar efficacy and safety profiles. This provides patients with greater access to critical cancer treatments at lower costs.## ConclusionIn conclusion, there have been several significant developments in the Pharma and Biotech industry recently. From promising results for COVID-19 vacci

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Vertex Pharmaceuticals experienced a 13% decrease in its share price following the disappointing results of its non-opioid pain therapy, suzetrigine, in a Phase II trial. Meanwhile, major players like Bayer, Bristol Myers Squibb, and Johnson & Johnson announced significant layoffs, impacting hundreds or even thousands of employees. Roche also faced setbacks as their Parkinson's drug failed to meet expectations in a mid-stage trial. Novartis made the decision to cut jobs in both Boston and Munich, while Mesoblast celebrated FDA approval for a mesenchymal stromal cell therapy for GVHD.On a more positive note, the FDA confirmed that there is no shortage of Lilly's GLP-1s and provided compounding pharmacies with a grace period before implementing new regulations to halt their production. Intelligencia AI's accurate pre-ASH predictions for high-potential biotechs demonstrated the efficacy of its predictive AI methodology. Amidst these challenges and changes, the biopharma industry is navigating evolving market dynamics and making strategic decisions to adapt to the shifting landscape.

Today's coverage kicks off with a market panel featuring Barbara Doran of BD8 Capital Partners and Phil Camporeale of J.P. Morgan Asset Management. Earnings highlights include RH, Broadcom, and Costco, with expert analysis from Bernstein's Stacy Rasgon on Broadcom and DA Davidson's Michael Baker on Costco. Globalstar CEO Paul Jacobs discusses investor day developments and reports of Apple Watch integration. Our Angelica Peebles reports on Vertex Pharmaceuticals' non-opioid pain medication and its potential market impact.

Las bolsas esperan el mensaje de Lagarde y la bajada de tipos del BCE. Pocos movimientos. Alemania con una ligera subida, Francia más pendiente de la política y España con el foco puesto en Grifols e Inditex. Aprovecharía el recorte de estos dos últimos días en Inditex para tomar posiciones: la zona de los 48/50 euros es un buen nivel de compra. Planteamos dentro de la bolsa española tb Repsol y BBVA, muy cerca de romper los 9.64 euros, resistencia importante. En nuestro Consultorio de Bolsa de hoy contamos con Samuel Plaza, Director de JFD BROKERS España. Con el analista vemos los siguientes valores: Colonial, Bayer, Inmobiliaria Colonial, Merlin Properties, Fresenius, TITAN Cement, Adidas, Marel, InPost, Farming Group, AENA, Vertex Pharmaceuticals, Palo Alto y IONQ.

In the fifth Season of the National Institute of Neurological Disorders and Stroke's Building Up the Nerve podcast, we help you strengthen your science communication skills with tools and advice to use throughout your career. We know that navigating your career can be daunting, but we're here to help—it's our job!In the sixth episode of the season, we talk about Writing Impactful Publications, focusing on how to structure and write a paper, choose a journal, and craft engaging and accessible figures.Featuring Bang Wong, MA, MS, Senior Director at Vertex Pharmaceuticals; Marina Picciotto, PhD, Professor at Yale University; and Tanya Garcia, PhD, Associate Professor at University of North Carolina, Chapel Hill.ResourcesReferenced paper by Dr. Amy Arnsten: Wang, Min, et al. "α2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex." Cell 129.2 (2007): 397-410. https://www.cell.com/fulltext/S0092-8674(07)00344-3?large_figure=true Referenced Papers by Bang Wong:Wong, B. Design of data figures. Nat Methods 7, 665 (2010). https://doi.org/10.1038/nmeth0910-665 Wong, B. Color coding. Nat Methods 7, 573 (2010). https://doi.org/10.1038/nmeth0810-573Wong, B. Points of view: Color blindness. Nat Methods 8, 441 (2011). https://doi.org/10.1038/nmeth.1618Check out more of Bang's papers: https://www.nature.com/search?author=Bang%20WongColor Contract website:Example: https://webaim.org/resources/contrastchecker/Writing Science: How to Write Papers That Get Cited and Proposals That Get Funded. By Joshua Schimel: https://global.oup.com/academic/product/writing-science-9780199760244 Experimental Design Editorials in the Journal of Neuroscience https://www.jneurosci.org/collection/experimental-design-editorialsTranscript available at http://ninds.buzzsprout.com/.

On today's episode of The Big Podcast, NBA legends reunite as we welcome basketball legend and kidney health advocate, Alonzo Mourning, to the show. Between Shaq and ‘Zo's battles on the court, their contrasting lifestyles (wait until you hear about ‘Zo's diet vs. Shaq's!), and other stories from back in the day, these two legends have plenty to laugh about. But it's not all jokes—Alonzo shares his powerful journey with APOL1-mediated kidney disease (AMKD) and his mission with Power Forward (www.PowerForwardTogether.com) to educate others about this rapidly progressive kidney disease. Tune in for an inspiring conversation and some classic Shaq-and-'Zo banter you don't want to miss!This episode is sponsored by Vertex Pharmaceuticals Incorporated. Alonzo Mourning is a paid spokesperson for Vertex Pharmaceuticals.Don't miss out on all the action this week at DraftKings! Download the DraftKings app today! Sign-up using https://dkng.co/ogs or through my promo code BIGPODZipRecruiter. The smartest way to hire. Go to this exclusive web address to try ZipRecruiter for FREE: http://ZipRecruiter.com/BIGDownload the Gametime app today or http://Gametime.co for $20 off your first order with code BIGPODBuy Liquid Death With Free Shipping on Amazon or http://liquiddeath.com/BIGPODWant to bite Shaq's head off? Get some Shaq-A-Licious at your local Walmart!Subscribe to The Big Podcast YouTube Channel to watch more episodes!Follow us on all platforms: https://linktr.ee/bigpodcast00:00 Intro02:18 Zo saved Shaq in the Finals?06:18 In memory of Dikembe Mutombo12:15 DK segment14:00 DK ad15:10 VRTX ad16:20 Lack of rivalries in current NBA19:05 Today's Big Men23:12 Gametime ad24:25 Liquid Death ad25:40 Alonzo opens up on forced retirement37:00 How Zo takes care of his health53:00 Shaq vs Heat Culture56:44 Being teammates with Shaq59:12 What current players could've handled their era?01:01:10 Zo reviews Shaq's diet and lifestyle01:05:35 Shaqalicious segment01:10:17 Vince Carter dunk01:13:09 Bench meme01:16:07 EndingGAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY).Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD).21+ and present in most states. (18+ DC/KY/NH/WY). Void in ONT/OR/NH. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS).1 per new customer. Min. $5 deposit. Min. $5 bet. Max. $150 issued as non-withdrawable Bonus Bets if your bet wins. Bonus Bets expire in 7 days (168 hours). Stake removed from payout. Terms: dkng.co/dk-offer-terms. Ends 1/5/25 at 11:59 PM ET. Sponsored by DK.MB01RGAXHH8FSSS#nba #lakers #shaq #bigpod #basketball #bigshaq #bigpodcast #alonzomorning Hosted on Acast. See acast.com/privacy for more information.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world.Beam Therapeutics reported a patient death in a gene editing trial for sickle cell disease, overshadowing otherwise positive data. Beam-101 was found to be competitive with approved treatments, highlighting the need for less-toxic preconditioning treatments. Sana Biotechnology is planning workforce cuts to reprioritize focus on its type 1 diabetes program and extend its cash runway. Astrazeneca has received promising early data for candidates in its obesity pipeline. Vertex Pharmaceuticals exceeded its Q3 forecast and raised full-year revenue guidance. Sana Biotechnology is gearing up for potential approvals for cystic fibrosis and non-opioid therapy. The FDA delayed a decision on Merus' bispecific antibody and lawsuits were filed by the family of Henrietta Lacks seeking a share of profits from HeLa cells.The impact of the presidential election on biopharma is being closely monitored.

APAC stocks began the week mostly positive but with the gains capped ahead of this week's major risk events including the US Presidential Election.PredictIt odds shifted over the weekend in favour of a Harris election victory; NYT/Siena final polls showed the race was deadlocked in 6/7 battleground states.European equity futures are indicative of a steady cash open with the Euro Stoxx 50 future +0.1% after the cash market closed higher by 1.0% on Friday.DXY is softer vs. peers in a scaling back of the USD supportive "Trump trade"; JPY and antipodeans have been the main beneficiaries.OPEC+ agreed to delay the December oil output increase by one month, according to a Reuters source.Looking ahead, highlights include EZ Sentix Index, Manufacturing PMIs, US Employment Trends, US Durable Goods, Australian PMIs (Final), Comments from ECB's Elderson, Supply from EU & US.Earnings from Volvo Car AB, Ryanair, Kingspan, Fidelity National Information Services, NXP Semiconductors, Vertex Pharmaceuticals, Diamondback Energy, Palantir Technologies, Marriott International & Fox.Read the full report covering Equities, Forex, Fixed Income, Commodites and more on Newsquawk

European bourses generally trade very modestly in positive territory, alongside slight gains in US futures.PredictIt odds shifted over the weekend in favour of a Harris election victory; NYT/Siena final polls showed the race was deadlocked in 6/7 battleground states.USD is on the backfoot as a shift in polling in the US election towards Harris has seen a scaling back of "Trump trades" across the board.USTs benefit from a scaling back of the Trump trade, whilst Bunds lag; reports suggesting that China's NPC is reviewing local government debt swaps weighed on the complex.Crude benefits amid reports that OPEC+ agreed to delay the December oil output increase by one month; base metals move higher in anticipation of the ongoing China NPC meeting.Looking ahead, US Employment Trends, Durable Goods, Australian PMIs (Final), Comments from ECB's Elderson, Holzmann, Supply from the US. Earnings from Fidelity National Information Services, NXP Semiconductors, Vertex Pharmaceuticals, Diamondback Energy, Palantir Technologies, Marriott International & Fox.Read the full report covering Equities, Forex, Fixed Income, Commodites and more on Newsquawk

WBZ NewsRadio's Chaiel Schaffel reports. 

In this episode, we hear the story of Vertex Pharmaceuticals, and it's a great one. Because their story is a people story. They've undergone tremendous transformation you might call Digital Transformation, but "digital" is a means to an end. At Vertex, transformation serves to amplify their tremendous culture and create talent velocity throughout the organization. Tune in to hear Kimberly Rose, Executive Director of People Experience, Analytics, and Digital Innovation in Human Resources ---- if a title doesn't illustrate the literal evolution of HR, we don't know what does. Kim shares how onboarding, career navigation, and managing people are all grounded in LISTENING TO PEOPLE at Vertex, and she reminds us one size does not fit all when it comes to employee experience.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world. This week's commercialization news includes Dupixent's success in a chronic hives study, Lilly's development of a weekly insulin shot, and BioMarin's plans for growth. The House backs a bill restricting China's role in US biotech, while Lykos CEO is set to depart after FDA rejection and layoffs. The newsletter also discusses key developments in cell therapy and offers insights on utilizing a direct-to-patient model in the healthcare industry. Various resources and upcoming events in the biopharma industry are also highlighted. Biopharma Dive provides in-depth journalism and insights into the latest news and trends shaping the biotech and pharma industries.BridgeBio has reduced its gene therapy budget after data from a trial on an adrenal gland medicine did not meet the company's investment threshold. GlaxoSmithKline has discontinued a herpes vaccine after it did not meet efficacy goals in a phase 2 study. Roivant has launched a new 'vant' focused on a hypertension drug. Centessa's sleepiness drug has shown promising results in early studies, leading to a rise in the company's shares. Additionally, Dupixent has succeeded in a chronic hives study, giving Sanofi and Regeneron a chance to resubmit their application for approval. Investors are also paying attention to Centessa's sleepiness drug. This news comes alongside updates on other pharmaceutical developments, such as Saxenda's effectiveness for children as young as 6 and Roche's expansion of R&D labs. Additionally, the newsletter covers upcoming events and resources for biopharma professionals. Biopharma Dive provides in-depth coverage of news and trends in the biotech and pharma industries, including clinical trials, FDA approvals, gene therapy, drug pricing, and research partnerships.Iowa has awarded Centene's subsidiary, Iowa Total Care, a Medicaid managed care contract worth $2.8 billion. Telehealth groups are urging Congress and the White House to extend controlled substance virtual prescribing before pandemic-era flexibilities expire. The Biden administration has finalized a rule raising mental health coverage standards for private plans. Steward Health Care received court approval to sell its three most valuable hospitals to Orlando Health for $439 million. The importance of data quality in realizing value from medical imaging data is emphasized by Enlitic. Payers are encouraged to optimize quality and grow revenue through key strategies in an upcoming webinar. Healthcare Dive provides in-depth journalism and insight into the most impactful news and trends shaping healthcare across various sectors like health IT, policy & regulation, insurance, digital health, payer-provider partnerships, and value-based care.Novo Nordisk showcased its investigational GLP-1 pill that resulted in a remarkable 13% weight loss. This comes after positive Phase I results for the pill, which analysts compared to weight loss pills being developed by Lilly and Pfizer. Expanded coverage for cardiovascular disease under Medicare could have significant implications for Novo's obesity drug, Wegovy. Analysts estimate that the expansion of Wegovy's label beyond obesity could lead to an annual Medicare spending of $145 billion. Meanwhile, GSK has abandoned the development of its herpes vaccine after disappointing Phase I/II results, and Crispr Therapeutics and Vertex Pharmaceuticals are facing challenges in making their sickle cell gene therapy profitable. Novo's other drug, Saxenda, was found to effectively and safely lower BMI in children, according to a study published in NEJM. Additionally, Lilly continues to make progress with its once-weekly insulin, while Bain has raised $3 billion for a fund supporting life sciences companies. The biopharmaceutical industry continues to see changes, with Biomarin facing challenges and Terns moving forward in the obesity spac

Get ready for an insightful conversation as host Rahul Chaturvedi connects with John Alam, CEO of CervoMed, to uncover the revolutionary advancements transforming dementia treatment, with a spotlight on Dementia with Lewy Bodies (DLB). John shares his remarkable journey from practicing medicine to leading cutting-edge biotech innovations, shedding light on the bold breakthroughs in neurodegenerative research and the intense, high-stakes world of clinical trials. This episode reveals how CervoMed is not just advancing dementia care but redefining it, proving that resilience and bold thinking are the keys to success in biotech. Biography: John Alam serves as the Chief Executive Officer at CervoMed, co-founding the company (formerly known as EIP Pharma) in 2014. John is an industry leader in translational medicine with over 30 years of experience creating value to help build companies through clinical development success. Until May 2014, he was therapeutic area head for diseases of aging at Sanofi, where he led all discovery and development activities directed at Alzheimer's disease, as well as a number of other age-related diseases including sarcopenia/frailty, osteoarthritis, chronic pain and many others. From 1997 to 2008, he held positions of increasing responsibility at Vertex Pharmaceuticals, including Chief Medical Officer and Executive Vice President, Medicines Development. At Vertex, he played major roles in the development of novel innovative medicines for HIV, Hepatitis C and Cystic Fibrosis. Prior to Vertex, Alam led clinical development of Avonex (interferon beta-1a) for multiple sclerosis at Biogen from 1991 to 1997. John is a member of the board of directors of the Alliance for Aging Research (AAR), a Washington, D.C. based non-profit organization dedicated to promoting innovation to address the healthcare needs of older Americans. He received a MD from Northwestern University School of Medicine and a BS in Chemical Engineering from the Massachusetts Institute of Technology. In addition, he completed an internal medicine residency at Brigham and Women's Hospital and a post-doctoral fellowship at Dana-Farber Cancer Institute.

2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. 

Join host Emily Walsh Martin, PhD, and David Altshuler, MD, PhD, Chief Scientific Officer of Vertex Pharmaceuticals. David came to Vertex after a lengthy career in medicine and academic research. David and Emily discuss how David and the team at Vertex think about innovation in drug development and how that impacts how they select programs and approaches for the diseases they focus on. They also cover what he'd love to see happen with new cell and gene platform technologies being brought forward. Now is the time to register for the ASGCT Policy Summit, held in Washington DC on September 23-24. Whether you attend in person or virtually, you will not want to miss this year's program. Great sessions are planned on reimbursement, Medicaid, venture capital, strategic investment outlooks, and the evolution of the regulatory landscape. Advanced registration ends August 23, so register today! ASGCT.org/PolicySummit Music by: https://www.steven-obrien.net/--------------------------Bright New Morning - Steven O'Brien (Used for free under a Creative Commons Attribution 4.0 License: https://creativecommons.org/licenses/by/4.0/)Show your support for ASGCT!: https://asgct.org/membership/donateSee omnystudio.com/listener for privacy information.

In this week's episode, Mary Winkels, Global Director, Medical Affairs Training and Capability at Vertex Pharmaceuticals discusses the MSL secret weapon for insightful engagement. Learn more about…

The 10-year Treasury yield rallied a bit after the minutes from the May 1 Fed meeting were released. Just after the close, the yield was trading around 4.43%, up 2 basis points. Oil and gas stocks lagged badly, along with metals and mining stocks. Loar Holdings followed through after clearing an IPO base Tuesday; Monday.com is holding gains well after gapping up on earnings; Vertex Pharmaceuticals is near the top of a shallow cup base.

Grace E. Niwa is a former piano prodigy who received a Master's Degree in Piano Performance from Juilliard, made her Carnegie Hall debut - and then decided to not pursue a professional career in music. Grace's subsequent professional life of multiple pivots includes being the Principal of her own PR firm and serving as Principal in a Global Executive Search firm. These days, Grace is the VP of Global Talent Acquisition, Talent Management and Early Career at the red-hot Vertex Pharmaceuticals, a global pharma powerhouse. Grace arrived at Vertex after serving as VP of Talent Acquisition and Executive at the equally celebrated Flagship Pioneering. Grace is a disruptor and visionary in the highly competitive world of Global Talent Acquisition, with a drive and discipline that are animated by her early training as a concert pianist.

Vertex Pharmaceuticals' acquisition of Alpine Immune Sciences will bolster a growing kidney disease franchise that could help diversify Vertex's business beyond its blockbuster cystic fibrosis franchise. On the latest BioCentury This Week podcast, BioCentury's editors discuss what attracted Vertex to Alpine and why it believes its newly acquired therapy can outshine others for IgA nephropathy. The editors discuss how Goldman Sachs aims to scale private biotechs via its venture strategy and the likely key factors for CMS as it determines prices for the first cohort of drugs in Medicare drug price negotiations under the Inflation Reduction Act. They also preview BioCentury's first R&D conference — Grand Rounds — which will focus on the biotech industry's interface with academia, bringing together decision-makers and the next innovators in Nashville, Sept. 9-11. This week's podcast is sponsored by Jeito Capital. 

In der heutigen Folge von „Alles auf Aktien“ sprechen die Finanzjournalisten Nando Sommerfeldt und Philipp Vetter über Inflations-Frust, ein episches Nvidia-Kursziel und ein Lob für Alibaba. Außerdem geht es um TSMC, Infineon, Nike, Lululemon, Under Armour, Adidas, Vertex Pharmaceuticals, Alpine Immune Sciences, Volkswagen, BMW, Mercedes-Benz, Stellantis, Mingyang, Goldwind, Siemens Energy, Oersted, Vestas, Rio Tinto, Glencore, Anglo American, Teck Resources, Newmont, Barrick Gold Agnico Gold Eagles, Hudbay Minerals, Pan American Silver, Albemarle, MP Materials, South32, Earth Gold Fund UI (A0Q2SD), Earth Exploration Fund UI (A0J3UF), VanEck Global Mining ETF (A2JDEJ). Wir freuen uns an Feedback über aaa@welt.de. Ab sofort gibt es noch mehr "Alles auf Aktien" bei WELTplus und Apple Podcasts – inklusive aller Artikel der Hosts und AAA-Newsletter.[ Hier bei WELT.](https://www.welt.de/podcasts/alles-auf-aktien/plus247399208/Boersen-Podcast-AAA-Bonus-Folgen-Jede-Woche-noch-mehr-Antworten-auf-Eure-Boersen-Fragen.html.) Disclaimer: Die im Podcast besprochenen Aktien und Fonds stellen keine spezifischen Kauf- oder Anlage-Empfehlungen dar. Die Moderatoren und der Verlag haften nicht für etwaige Verluste, die aufgrund der Umsetzung der Gedanken oder Ideen entstehen. Hörtipps: Für alle, die noch mehr wissen wollen: Holger Zschäpitz können Sie jede Woche im Finanz- und Wirtschaftspodcast "Deffner&Zschäpitz" hören. Außerdem bei WELT: Im werktäglichen Podcast „Das bringt der Tag“ geben wir Ihnen im Gespräch mit WELT-Experten die wichtigsten Hintergrundinformationen zu einem politischen Top-Thema des Tages. +++ Werbung +++ Du möchtest mehr über unsere Werbepartner erfahren? [**Hier findest du alle Infos & Rabatte!**](https://linktr.ee/alles_auf_aktien) Impressum: https://www.welt.de/services/article7893735/Impressum.html Datenschutz: https://www.welt.de/services/article157550705/Datenschutzerklaerung-WELT-DIGITAL.html

On this episode, we speak with Katie Weissman from Vertex Pharmaceuticals to learn about their company culture, investment in early-career talent and much more.

2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/

Last month the FDA approved a new treatment for sickle cell disease, the first medical therapy to use CRISPR gene editing technology. It works by identifying the gene or genes causing the disorder, modifying those genes and then returning them to the patient's body.There are now two gene therapies offered by pharmaceutical companies for sickle cell disease: Casgevy from Vertex Pharmaceuticals and CRISPR Therapeutics, and Lyfgenia from BlueBird Bio. But prices for these one-time treatments are steep: Casgevy costs $2.2 million per patient and Lyfgenia $3.1 million.Both promise a full cure, which would be life-changing for patients with this debilitating condition. Over 100,000 Americans, mostly of African descent, have sickle cell disease.This milestone raises more questions: What will be the next disease that CRISPR can help cure? And is it possible to reduce the costs of gene therapy treatments?Ira talks with Dr. Fyodor Urnov, professor of molecular and cell biology and scientific director of technology and translation at the Innovative Genomics Institute, based at the University of California, Berkeley, about the future of CRISPR-based cures.Transcripts for this segment will be available the week after the show airs on sciencefriday.com. To stay updated on all things science, sign up for Science Friday's newsletters.

Listen to Len Bacharier, MD and Sharon Dell, MD, FRCPC, as they highlight the natural course of pediatric asthma progression over time, discuss differences between spontaneous remission and on-treatment clinical remission, and provide a commentary on what we have learned from the recent developments around remission in adults and how it could relate more specifically to pediatric populations.   ADVENT is a medical education non-promotional resource for healthcare professionals organized by Sanofi and Regeneron. Learn more at ADVENTprogram.com. This podcast is intended for healthcare professionals only. Disclaimer:  This program is non-promotional and is sponsored by Sanofi and Regeneron Pharmaceuticals, Inc. The speakers are being compensated and/or receiving an honorarium from Sanofi and Regeneron in connection with this program The content contained in this program was jointly developed by the speakers and Sanofi and Regeneron and is not eligible for continuing medical education (CME) credits Speaker disclosures: Len Bacharier, MD has served as an advisor, consultant, speaker, and/or investigator for AstraZeneca, Avillion, DBV Technologies, Genentech/Novartis, GlaxoSmithKline, Kinaset, OM Pharma, Recludix, Regeneron Pharmaceuticals, Inc., Sanofi, Vertex; has provided grant and/or research support for NIH (NHLBI, NIAID), Regeneron Pharmaceuticals, Inc., Sanofi; and has provided other support for DBV Technologies Sharon Dell, MD has served as an advisor, consultant, and/or speaker for  AstraZeneca, Novartis, Regeneron Pharmaceuticals, Sanofi; and has provided grant and/or research support for Boehringer Ingelheim, Merck, Parion Sciences, Sanofi, Vertex Pharmaceuticals © 2023 Sanofi and Regeneron Pharmaceuticals, Inc. All Rights Reserved. MAT-GLB-2305935 v1.0 12/2023 MAT-US-2305475 v1.0 - P Expiration Date: 12/22/2025

Frank Holland and the investment committee debate the road ahead for your money. The panel reacts to the recent tear in transportation stocks. The call of the day is on Vertex Pharmaceuticals. The chart of the day is on lithium. Investment Committee Disclosures

Dow rises more than 500 points to a new record high. Plus: Apple shares climb 1.7% to their highest level ever. Vertex Pharmaceuticals shares finish 13.2% higher after it reported promising study results for one of its experimental pain medicines. J.R. Whalen reports. Learn more about your ad choices. Visit megaphone.fm/adchoices

Scott Wapner and the investment committee discuss the tech run as the Nasdaq goes for its longest winning streak in two years. The experts detail their latest portfolio moves. The calls of the day are on Nike, Home Depot and Lowe's. Earnings movers include Uber, Vertex Pharmaceuticals and NXP Semi. The desk debates the energy trade with oil prices at two-month lows.Investment Committee Disclosures

  A former Samsung executive allegedly stole plans in order to build a chip plant down the road from the existing factory. What could possibly go wrong? (00:15) Bill Mann and Deidre Woollard discuss: - The high value of getting a leg up on the competition in the semiconductor industry. - If companies can do anything to keep secrets from leaking out. - Why Alphabet's adtech is attracting regulators' attention. (13:53) Ricky Mulvey and Kirsten Guerra take a look at Vertex Pharmaceuticals and its role at the center of cystic fibrosis treatment. Companies discussed: GOOG, GOOGL,KO, VRTX, SSNLFHost: Deidre Woollard Guests: Bill Mann, Ricky Mulvey, Kirsten Guerra Producer: Ricky Mulvey Engineer: Tim Sparks