Podcasts about cognitive dysfunction

How does dysfunction in cognition affect overall treatment outcomes for psychiatric disorders? What are the challenges in treating cognitive deficits in psychiatric conditions? What treatments are in development for cognitive dysfunction? Brought to you by the NEI Podcast, the PsychopharmaStahlogy Show tackles the most novel, exciting, and controversial topics in psychopharmacology in a series of themes. This theme is on the “untreatable” dimensions of psychopathology. Today, Dr. Andy Cutler interviews Dr. Richard Keefe and Dr. Stephen Stahl about the clinical difficulties of treating cognitive dysfunction.  Let's listen to Part 2 of our theme: Untreatable Dimensions of Psychopathology. Subscribe to the NEI Podcast, so that you don't miss another episode! ***Register today for the 7th annual NEI Synapse, being held April 19th through the 21st in-person in Las Vegas and online via simulcast. Use discount code PODCAST to save $100 on your registration at nei.global/Synapse.

In this episode of Paws and Listen, Johnny Manning (a.k.a Manno) chats with Veterinarian Dr Nicole Rous about cognitive decline in pets. They explore how cognitive decline can impact your relationship with your pet, how to identify it and some preventative measurements you can take. Tune in to learn how you can help your furry friends stay sharp and happy as they age.   Cognitive Dysfunction Syndrome Evaluation Tool: https://www.purinainstitute.com/sites/default/files/2021-04/DISHAA-Assessment-Tool.pdf More about Cognitive Dysfunction in cats and dogs: https://todaysveterinarypractice.com/neurology/management-of-dogs-and-cats-with-cognitive-dysfunction/   The link from gut: https://www.sciencealert.com/in-a-huge-first-scientists-transfer-alzheimers-to-healthy-young-animals?fbclid=IwAR2Vwn9J27YeJHiPbof2GaYPQ9VQGjVWhMZdHhmfb19GoibsdVJP0_c6lBs Produced and edited by Camilla Falkowski  

In this episode, Dr. Linda Bluestein interviews Dr. Ilene Ruhoy about causes of brain fog, as well as its relationship to various conditions such as mast cell activation syndrome, craniocervical instability, dysautonomia, and CSF leaks. She explains how these conditions contribute to cognitive dysfunction and the importance of identifying underlying causes. Dr. Ruhoy emphasizes the need for a comprehensive evaluation and individualized treatment approach for patients experiencing brain fog.  They delve into the role of nutrition in cognitive function, emphasizing the impact of food choices on inflammation. They highlight the importance of avoiding processed foods and sugar, increasing vegetable consumption, and improving lifestyle factors.  Dr. Ruhoy shares surprising findings on the MRI of mast cell activation syndrome (MCAS) patients. YOUR host, as always, is Dr. Linda Bluestein, the Hypermobility MD.TakeawaysBrain fog is characterized by cognitive difficulties such as slow thinking, difficulty learning and recalling information, and trouble focusing and paying attention.Conditions such as mast cell activation syndrome (MCAS), craniocervical instability (CCI), dysautonomia, Ehlers-Danlos Syndromes, and CSF leaks can contribute to cognitive dysfunction and brain fog.Intracranial hypertension (high pressure), hypotension (low pressure), and Tarlov cysts can also contribute to brain fog. Identifying the underlying causes of brain fog is crucial for developing an effective treatment plan.A comprehensive evaluation, including medical history, imaging studies, and laboratory tests, can help determine the contributing factors and guide treatment decisions. Applying knowledge gained from podcasts and research in clinical practice can help healthcare professionals provide better care to their patients.Making a meaningful difference in patients' lives is a rewarding aspect of being a healthcare professional.Nutrition plays a crucial role in cognitive function, and food choices can either be anti-inflammatory or pro-inflammatory.Avoiding processed foods and sugar, increasing vegetable consumption, and improving lifestyle factors can positively impact cognitive function.Chapters00:00 Introduction of Dr. Ilene Ruhoy01:57 Defining Brain Fog04:14 Risk Factors for Brain Fog09:42 Identifying Contributing Factors11:52 Cognitive Dysfunction and Mast Cell Activation Syndrome14:09 Cognitive Dysfunction and Craniocervical Instability18:18 Cognitive Dysfunction and CSF Leak22:59 Cognitive Dysfunction and Dysautonomia25:25 Cognitive Dysfunction and Upper Cervical Instability30:12 Cognitive Dysfunction and CSF Leak38:11 Applying Knowledge in Clinical Practice39:04 The Importance of Making a Meaningful Difference40:31 The Role of Nutrition in Cognitive Function42:38 The Impact of Food Choices on Inflammation43:44 Avoiding Processed Foods and Sugar44:38 The Role of Complex Carbohydrates and Dairy45:28 Increasing Vegetable Consumption46:44 Improving Lifestyle Factors47:09 Where to Find Dr. Ilene Ruhoy OnlineConnect with YOUR Bendy Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/.   Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them.Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/.      YOUR bendy body is our highest priority!

In this episode, Dr. Linda Bluestein interviews Dr. Ilene Ruhoy about causes of brain fog, as well as its relationship to various conditions such as mast cell activation syndrome, craniocervical instability, dysautonomia, and CSF leaks. She explains how these conditions contribute to cognitive dysfunction and the importance of identifying underlying causes. Dr. Ruhoy emphasizes the need for a comprehensive evaluation and individualized treatment approach for patients experiencing brain fog.  They delve into the role of nutrition in cognitive function, emphasizing the impact of food choices on inflammation. They highlight the importance of avoiding processed foods and sugar, increasing vegetable consumption, and improving lifestyle factors.  Dr. Ruhoy shares surprising findings on the MRI of mast cell activation syndrome (MCAS) patients. YOUR host, as always, is Dr. Linda Bluestein, the Hypermobility MD.TakeawaysBrain fog is characterized by cognitive difficulties such as slow thinking, difficulty learning and recalling information, and trouble focusing and paying attention.Conditions such as mast cell activation syndrome (MCAS), craniocervical instability (CCI), dysautonomia, Ehlers-Danlos Syndromes, and CSF leaks can contribute to cognitive dysfunction and brain fog.Intracranial hypertension (high pressure), hypotension (low pressure), and Tarlov cysts can also contribute to brain fog. Identifying the underlying causes of brain fog is crucial for developing an effective treatment plan.A comprehensive evaluation, including medical history, imaging studies, and laboratory tests, can help determine the contributing factors and guide treatment decisions. Applying knowledge gained from podcasts and research in clinical practice can help healthcare professionals provide better care to their patients.Making a meaningful difference in patients' lives is a rewarding aspect of being a healthcare professional.Nutrition plays a crucial role in cognitive function, and food choices can either be anti-inflammatory or pro-inflammatory.Avoiding processed foods and sugar, increasing vegetable consumption, and improving lifestyle factors can positively impact cognitive function.Chapters00:00 Introduction of Dr. Ilene Ruhoy01:57 Defining Brain Fog04:14 Risk Factors for Brain Fog09:42 Identifying Contributing Factors11:52 Cognitive Dysfunction and Mast Cell Activation Syndrome14:09 Cognitive Dysfunction and Craniocervical Instability18:18 Cognitive Dysfunction and CSF Leak22:59 Cognitive Dysfunction and Dysautonomia25:25 Cognitive Dysfunction and Upper Cervical Instability30:12 Cognitive Dysfunction and CSF Leak38:11 Applying Knowledge in Clinical Practice39:04 The Importance of Making a Meaningful Difference40:31 The Role of Nutrition in Cognitive Function42:38 The Impact of Food Choices on Inflammation43:44 Avoiding Processed Foods and Sugar44:38 The Role of Complex Carbohydrates and Dairy45:28 Increasing Vegetable Consumption46:44 Improving Lifestyle Factors47:09 Where to Find Dr. Ilene Ruhoy OnlineConnect with YOUR Bendy Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/.   Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them.Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/.      YOUR bendy body is our highest priority!

Dr. Nate Ritter interviews Dr. Lauren Stump, a veterinarian with Nestle Purina PetCare, about epilepsy. Epilepsy is a common, chronic neurological disease and a risk to health and welfare in dogs. Canine Cognitive Dysfunction Syndrome is a common, age-related disease caused by gradual and degenerative changes in the brain. Dr. Stump discusses these conditions and possibilities for nutritional management.Education is at the core of our mission here at Good Dog, and we're always finding new ways to provide the latest and greatest in canine health and research to our community of Good Breeders. We're excited to offer members of our community free and exclusive access to Good Dog Courses, a series of online educational courses that include in-depth videos, checklists, breeding tools, and more.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.28.550986v1?rss=1 Authors: Henry, R. J., Barrett, J. P., Vaida, M., Khan, N. Z., Makarevich, O., Ritzel, R. M., Faden, A. I., Stoica, B. A. Abstract: Obesity increases the morbidity and mortality of traumatic brain injury (TBI). We performed a detailed analysis of transcriptomic changes in the brain and adipose tissue to examine the interactive effects between high-fat diet-induced obesity (DIO) and TBI in relation to central and peripheral inflammatory pathways, as well as neurological function. Adult male mice were fed a high-fat diet (HFD) for 12 weeks prior to experimental TBI and continuing after injury. Combined TBI and HFD resulted in additive dysfunction in the Y-Maze, novel object recognition (NOR), and Morris water maze (MWM) cognitive function tests. We also performed high-throughput transcriptomic analysis using Nanostring panels of cellular compartments in the brain and total visceral adipose tissue (VAT), followed by unsupervised clustering, principal component analysis, and IPA pathway analysis to determine shifts in gene expression programs and molecular pathway activity. Analysis of cellular populations in the cortex and hippocampus as well as in visceral adipose tissue during the chronic phase after combined TBI-HFD showed amplification of central and peripheral microglia/macrophage responses, including superadditive changes in select gene expression signatures and pathways. These data suggest that HFD-induced obesity and TBI can independently prime and support the development of altered states in brain microglia and visceral adipose tissue macrophages, including the disease-associated microglia/macrophage (DAM) phenotype observed in neurodegenerative disorders. The interaction between HFD and TBI promotes a shift toward chronic reactive microglia/macrophage transcriptomic signatures and associated pro-inflammatory disease-altered states that may, in part, underlie the exacerbation of cognitive deficits. Targeting of HFD-induced reactive cellular phenotypes, including in peripheral adipose tissue macrophages, may serve to reduce microglial maladaptive states after TBI, attenuating post-traumatic neurodegeneration and neurological dysfunction. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.03.547282v1?rss=1 Authors: Bjornson, K. J., Vanderplow, A. M., Yang, Y., Kermath, B. A., Cahill, M. E. E. Abstract: The effects of repeated stress on cognitive impairment are thought to be mediated, at least in part, by reductions in the stability of dendritic spines in brain regions critical for proper learning and memory, including the hippocampus. Small GTPases are particularly potent regulators of dendritic spine formation, stability, and morphology in hippocampal neurons. Through the use of small GTPase protein profiling in mice, we identify increased levels of synaptic Rap1 in the hippocampal CA3 region in response to escalating, intermittent stress. We then demonstrate that increased Rap1 in the CA3 is sufficient in and of itself to produce stress-relevant dendritic spine and cognitive phenotypes. Further, using super-resolution imaging, we investigate how the pattern of Rap1 trafficking to synapses likely underlies its effects on the stability of select dendritic spine subtypes. These findings illuminate the involvement of aberrant Rap1 regulation in the hippocampus in contributing to the psychobiological effects of stress. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

On this episode of the podcast I discuss the term "brain fog" and if this is appropriate when talking about neurological impairment in Long Covid. I discuss research and two papers which explain neurological complications with Long Covid and other post viral conditions. Cognitive dysfunction is scary, experiencing the loss of words, forgetting full conversations, moments in your life. Cognitive dysfunction effects many of our systems and evokes a multitude of associated symptoms. I also discuss how cognitive impairment is often suggested by medical professionals, as being a mental health condition, anxiety/depression rather than being acknowledged as cognitive dysfunction. This is detrimental to any treatment or therapies required for either/or cognitive dysfunction or mental health. It is imperative that further research is undertaken, and medical professionals have extended training, on the multi complex condition Long Covid is and how to appropriately address and treat the associated symptoms that effect the person, physically, cognitively, emotionally and mentally. I hope you enjoy this podcast and always please take care. Nature reviews microbiology - Hannah. E. Davies et elhttps://www.nature.com/articles/s41579-022-00846-2National Library of medicine - Brain fog as a long-term sequela of covid 19https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685075/My Links:https://linktr.ee/joulesthttps://twitter.com/julieTa58407536https://www.facebook.com/livingwithlongcovid/https://www.instasgram.com/julietaylor9545https://amzn.eu/d/9v9MP4v

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.12.536572v1?rss=1 Authors: Dues, D. J., Nguyen, A. P. T., Becker, K., Ma, J., Moore, D. J. Abstract: Cognitive dysfunction is a salient feature of Parkinson's disease (PD) and Dementia with Lewy bodies (DLB). The onset of dementia reflects the spread of Lewy pathology throughout forebrain structures. The mere presence of Lewy pathology, however, provides limited indication of cognitive status. Thus, it remains unclear whether Lewy pathology is the de facto substrate driving cognitive dysfunction in PD and DLB. Through application of -synuclein fibrils in vivo, we sought to examine the influence of pathologic inclusions on cognition. Following stereotactic injection of -synuclein fibrils within the mouse forebrain, we measured the burden of -synuclein pathology at 1-, 3-, and 6-months post-injection within subregions of the hippocampus and cortex. Under this paradigm, the hippocampal CA2/3 subfield was especially susceptible to -synuclein pathology. Strikingly, we observed a drastic reduction of pathology in the CA2/3 subfield across time-points, consistent with the consolidation of -synuclein pathology into dense somatic inclusions followed by neurodegeneration. Silver-positive degenerating neurites were observed prior to neuronal loss, suggesting that this might be an early feature of fibril-induced neurotoxicity and a precursor to neurodegeneration. Critically, mice injected with -synuclein fibrils developed progressive deficits in spatial learning and memory. These findings support that the formation of -synuclein inclusions in the mouse forebrain precipitate neurodegenerative changes that recapitulate features of Lewy-related cognitive dysfunction. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

People with kidney disease often present with cognitive dysfunction ranging from mild impairment to dementia often effecting memory, language skills, attention span, and other functions including depression.  Nephrologist Mark Unruh, MD, Professor and Chair of the Department of Internal Medicine at the University of New Mexico, discusses cognitive impairment in patients with Chronic kidney disease and his research to find targeted interventions to address these challenges.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.11.516192v1?rss=1 Authors: Orsini, F., Argyrousi, E. K., Restelli, E., Ford, L. K., Takamura, H., Matsuzaki, S., Zentilin, L., Pascente, R., Kanaan, N. M., Soni, R., Katayama, T., Chiesa, R., Forloni, G., Kosik, K. S., Kandel, E. R., Fraser, P. E., Arancio, O., Fioriti, L. Abstract: Abnormal intracellular accumulation of Tau aggregates is a hallmark of Alzheimer's disease (AD) and other Tauopathies, such as Frontotemporal dementia (FTD), which can be caused by mutations of Tau. Mutated and pathological Tau can undergo a range of post-translational modifications (PTMs) that might trigger or modulate disease pathology. Recent studies indicate that modification of wild type Tau by Small ubiquitin-like modifier SUMO isoform 1 (SUMO1) controls Tau hyperphosphorylation and aggregation, suggesting that SUMOylation acts as a central regulator of Tau's biochemical properties. Besides SUMO1, Tau is modified by SUMO2/3, however the consequences of this modification have not been investigated. Here, using viral approaches on primary hippocampal neurons, transgenic mice expressing mutant Tau and SUMO2, and iPSC-derived neurons from FTD patients, we evaluated whether SUMO2/3 conjugation modifies the neurodegenerative disease pathology associated with the aggregation-prone mutant Tau P301L, P301S, and R406W variants. We found that mutant forms of Tau are targets of SUMO2/3, and SUMO2/3 conjugation is neuroprotective. Importantly, expression of mutant Tau is accompanied by a significant reduction of SUMO2/3 conjugation levels, and restoring levels of SUMO2 reduces mutant Tau aggregation and phosphorylation in all model systems Furthermore, overexpression of SUMO2 restores levels of pre- and post-synaptic markers, associated with a complete rescue of the LTP and memory deficits in transgenic mice expressing mutant Tau. These findings bring to light the potential therapeutic implication of manipulating SUMO conjugation to detoxify Tau through PTM-based approaches. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.05.511002v1?rss=1 Authors: Lyu, J., Nagarajan, R., Kambali, M., Wang, M., Rudolph, U. Abstract: The cellular basis of age-related impairments of hippocampal function is not fully understood. In order to evaluate the role of somatostatin-positive (Sst+) interneurons in the dentate gyrus hilus in this process, we chemogenetically inhibited Sst+ interneurons in the dentate gyrus (DG) hilus. Chronic chemogenetic inhibition (CCI) of these neurons resulted in increased c-Fos staining in the DG hilus, a decrease in the percentage of Gad67- and of Sst-expressing neurons in the DG, and increased microglial activation in DG, CA3, and CA1. Total dendritic length and spine density were reduced in DG and CA1, suggesting reduced dendritic complexity. Behaviorally, the recognition index in an object recognition task and the percentage of spontaneous alternations in the Y maze were decreased, while in both initial and reversal learning in the Morris water maze the latencies to find the hidden platform were increased, suggesting cognitive dysfunction. Our findings establish a causal role for a reduced function of Sst+ interneurons in the DG hilus for cognitive decline and suggest that this reduced function may contribute to age-related impairments of learning and memory. Our CCI mice may represent a cellularly defined model of hippocampal aging. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

Drs Anne Cross and Lauren Krupp talk about the latest research and their real-life experience identifying and treating cognitive dysfunction in patients with MS in the busy clinic setting. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/977030). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals. Resources Multiple Sclerosis https://emedicine.medscape.com/article/1146199-overview A Preliminary Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) Tool in an Irish Population With Multiple Sclerosis (MS) https://www.msard-journal.com/article/S2211-0348(15)00111-X/fulltext Digital Cognitive Testing Uncovers Hidden Impairment in MS https://www.medscape.com/viewarticle/892482 MIND Diet Adherence Might Be Associated With a Reduced Odds of Multiple Sclerosis: Results From a Case-Control Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857348/ Pediatric Multiple Sclerosis: Cognition and Mood https://n.neurology.org/content/87/9_Supplement_2/S82.long Experimental Autoimmune Encephalomyelitis (EAE) as a Model for Multiple Sclerosis (MS) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229753/ Cognitive Dysfunction in Early-Onset Multiple Sclerosis https://jamanetwork.com/journals/jamaneurology/fullarticle/780539

August 2017 Functional Neuroimaging Correlates of Postoperative Cognitive Dysfunction by SNACC

Duane Peters from the Lupus Foundation of America interviews Dr Erik Anderson and Dr Meggan Mackay from the Feinstein Institutes for Medical Research in New York in the USA. They discuss their study into imbalances in quinolinic acid and kynurenic acid levels in the brain in SLE patients, and propose that the ratio between these two metabolites could be used as a new biomarker or therapeutic target for cognitive dysfunction. Access the paper here: https://lupus.bmj.com/content/8/1/e000559

There is much discussion these days around the diagnosis of dementia in humans. But what about our canine companions? Like people, dogs can suffer from Canine Cognitive Disorder, otherwise known as dog dementia. This degenerative brain condition results in impaired memory, strange or unexplained behavior, weakened thinking skills. It is estimated that 14 to 30 percent of older dogs will develop dog dementia. And while the cause of dementia in dogs is not always clear, there are some things you can do to help your furry friend if you think he may be experiencing dog dementia. In this #Lifewitholddogs blog post and podcast, we'll discuss what dog dementia is, how to recognize the symptoms, and ways to help your senior German Shepherd live his best life despite the condition.Here is the link for our correlating blog post on Dog Dementiahttps://www.wpsgss.org/post/canine-cognitive-dysfunction-otherwise-known-as-dog-dementia-is-a-real-issue In season three of our #LifeWithOldDogs podcast and blog we are covering the top 20 health issues of senior German Shepherds, so be sure to subscribe to our newsletter to get all this free and valuable information delivered right to your inbox.To subscribe, go to: www.wpsgss.org  Scroll halfway down and look for the "Join our mailing list" postcard.Our fur friends don't live forever.....none of us do.... but as your German Shepherd ages, it's important to know the typical aliments your fur friend can suffer from and how to navigate the waters if something does come up, instead of being blindsided and feeling helpless. We want to help you with that. At the end of season three of #LifeWithOldDogs podcast and blog posts, we will send you the entire season's worth of all the information we cover in a FREE ebook, so be sure to subscribe to be "in the Know."You can find Woody's Place Senior German Shepherd Sanctuary online at:www.wpsgss.orghttps://www.facebook.com/woodysplacesgsshttps://www.instagram.com/wpsgss/https://www.youtube.com/channel/UC7Tb1hKnOWEamQstkqAxEygWe would LOVE it if you could leave a thumbs up or comment! Please and Thank you!Support the show (http://www.patreon.com/#LifeWithOldDogs)

Duane Peters from the Lupus Foundation of America interviews Jennifer He from the University of Western Ontario in Canada about her research into using neuropsychological battery tests to determine the degree of cognitive dysfunction in lupus patients. A high degree of variability in performance across multiple tests (a high dispersion score) is associated with a higher risk of cognitive dysfunction, so this can be a useful screening/diagnostic tool. Access the paper here: https://lupus.bmj.com/content/8/1/e000511

In this episode you will find what research states about elderly-onset of sle. Also you will hear about the Wide Differences in Thinking Skills and Abilities Linked to Cognitive Dysfunction in Lupus Patients. Did you know that individuals with sle are at a higher risk of cancer. You will also hear my health update and a tribute to my mother. Resources Lupus Foundation Of America (14, October 2021) Wide Differences in Thinking Skills and Abilities Linked To Cognitive Dysfunction in Lupus National Library Of Medicine (31, October 2021) Elderly-onset systemic lupus erythematosus: prevalence, clinical course and treatment John Hopkins Lupus Center (31, October 2021) Lupus and Cancer Susan Hendrix (01, November 2021 Health Update #lupus #elderlyonset #cognitivedysfunctioninlupus #lupusandcancer #mystorylivingwithlupuspodcast --- Send in a voice message: https://anchor.fm/susan-hendrix/message

Season #2 Episode 23. CBD For Your Pet. Scam or Miracle Cure? Interview with Dr. Terry Fossum DVM  from Dr. Fossum's Pet Products, CBD, and Cogni Caps for Senior Dogs with Canine Cognitive Dysfunction.   Dog Training, Dog Trainer, Cat Training, Cat Trainer, Pet Training, Pet Trainer, Dog Behaviorist, Phoenix Dog Training Will Bangura is a Professional Dog Behaviorist who specializes in dog aggression training in Phoenix ArizonaSupport the show (https://PetTalkToday.com)

Join Drs. Kelly Diehl and Margaret Gruen as they discuss cognitive dysfunction in dogs (and cats), including signs of decline, monitoring tools and quality of life for both pets and owners.

Day 135 – It always seems to be raining, almost like April Showers in May, suspect the Greenhouse effect is playing its part with this changing weather we've seen over the last couple of years. Willow's behaviour, it's getting worse, she's so fearful of everybody and everything. She completely breaks down if I'm not around, even if Dave is. I am most certainly her security blanket. She has started barking at people for no reason other than they are behind her. Generally, the rule of thumb used to be not keen on men, but now she's just really anxious and anything can set her off. A bike whizzing past, that never used to bother her, now she tries to see them off. Someone calling her name, she physically cowers behind me. Dave coming into the boat, well everyone on the Marina knows when Dave's home. The vets have always scared her, but the fears are growing with the advancing years, and I find myself in new dog territory. I do believe there is nothing physically wrong with her, but mentally it all seems to be disintegrating in her head. If she had a boo-boo, I could see it, deal with it - clean it and dress it, but with something going on in her head – what do I do? Dave thinks I'm overreacting, but I can see the change in her mentally, my heart just nearly chipped to see her standing in the middle of the room violently shaking because the rain was bouncing on our roof. I didn't want to coo coo comfort her too much and thereby reinforcing the behaviour she still stood there shaking looking all forlorn and sad. My heart went out to her really it did. Maybe she needs anti-anxiety tablets, a thunder vest, herbal sprays I just don't know. I find myself at a loss. If you've enjoyed this episode, please leave us a five-star rating or review and share it with those you feel would also enjoy them. Don't forget to follow us, here for future episodes – once again thank you for listening. Same walk different viewpoints - Come say Hi at; Our website - https://changingpace.co.uk Louise's (Couch Potato) account of the walks can also be found here; 1. https://twitter.com/NbChangingPac 2. https://www.facebook.com/NBChangingPace 3. https://www.instagram.com/nbchangingpace 4. https://www.tiktok.com/@narrowboatchangingpace 5. https://www.youtube.com/c/NarrowboatChangingPace Willow's (Great Dane) account of the walks can also be found here; 1. https://www.facebook.com/WillowTheGreatDane 2. https://www.instagram.com/willowwalks1000miles 3. https://www.tiktok.com/@willowwalks1000miles 4. https://www.youtube.com/channel/UCBdl0W-Q_vJQmQQ3Ae1Bogw PLEASE NOTE - We are not contracted or affiliated with the official #walk1000miles challenge, we are just participants - https://www.walk1000miles.co.uk Some of our posts contain affiliate links, We earn a small commission if you choose to make a purchase using these links, they cost you nothing extra. Every little click helps, thank you for supporting us. --- Send in a voice message: https://anchor.fm/narrowboat-changing-pace/message

In this podcast, Dr Sarah Caney talks about cognitive dysfunction syndrome (CDS) which is similar to Alzheimer's disease in people. Sarah explains what the common behaviour changes are with this condition, how it can be investigated by vets and how carers can support their affected cat. 

We are back! After a bit of a break we are releasing the first of two episodes on Cognitive Dysfunction in our senior pets. This is a VERY common disease and it is very helpful to know the signs and symptoms. 

In today's VETgirl podcast, we interview Dr. Amy Pike, DACVB on separation anxiety, COVID, cognitive dysfunction syndrome (CDS) and all things behavior! With COVID, what should we veterinary professionals do with the spike in separation anxiety once pet owners return to work? Tune in to learn all about all things behavioral, including natural and prescription behavioral medications to reach for, and how to identify, recognize and treat behavioral problems in veterinary medicine. Finally, are you recognizing cognitive dysfunction syndrome (CDS) in dogs and cats? An often under-diagnosed medical condition, find out what we can do to help recognize CDS more readily and monitor its progression in dogs. As CDS affects an estimated 14% of dogs over 8 years of age, tune in to learn what you can do to combat age-related neurodegeneration.

This piece gets deep into a much needed discussion regarding frailty, delirium, post-operative cognitive dysfunction and brain health. Noted as one of the highlights of the year in our recent holiday specials and previously only available to attendees to the incredibly successful EBPOM Chicago 2020; go to www.ebpom.org now for more details on forthcoming events and special offers now. This piece is part two of two. This piece gets a mention "End of life decision planning in the perioperative setting: the elephant in the room?" https://academic.oup.com/bja/article/115/5/648/230412?login=true The Global Council on Brain Health is here on the American Association of Retired People's website: https://www.aarp.org/health/brain-health/global-council-on-brain-health/ This is part one of a two part piece, part two features questions from the online conference audience. Presented by Monty Mythen with Angela Bader, Professor of Anesthesia at Harvard Medical School and Vice Chair for Perioperative Medicine in the Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital, founding Director of the Weiner Center for Preoperative Evaluation, Sarah Lenz Lock, Senior Vice President for Policy and Brain Health in the American Association of Retired People's (AARP) Policy, Research and International Affairs (PRI), Executive Director of the Global Council on Brain Health, Jeanna Blitz associate professor of Anesthesiology at Duke University School of Medicine, Director of the Preoperative Anesthesia Surgical Screening (PASS) Clinic. There's also a surprise appearance from the EBPOM Chicago 2020 host, Sol Aronson, tenured Professor at Duke University.

This piece gets deep into a much needed discussion regarding frailty, delirium, post-operative cognitive dysfunction and brain health. Noted as one of the highlights of the year in our recent holiday specials and previously only available to attendees to the incredibly successful EBPOM Chicago 2020; go to www.ebpom.org now for more details on forthcoming events and special offers. This piece gets a mention "End of life decision planning in the perioperative setting: the elephant in the room?" https://academic.oup.com/bja/article/115/5/648/230412?login=true The Global Council on Brain Health is here on the American Association of Retired People's website: https://www.aarp.org/health/brain-health/global-council-on-brain-health/ This is part one of a two part piece, part two features questions from the online conference audience. Presented by Monty Mythen with Angela Bader, Professor of Anesthesia at Harvard Medical School and Vice Chair for Perioperative Medicine in the Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital, founding Director of the Weiner Center for Preoperative Evaluation, Sarah Lenz Lock, Senior Vice President for Policy and Brain Health in the American Association of Retired People's (AARP) Policy, Research and International Affairs (PRI), Executive Director of the Global Council on Brain Health, Jeanna Blitz associate professor of Anesthesiology at Duke University School of Medicine, Director of the Preoperative Anesthesia Surgical Screening (PASS) Clinic. There's also a surprise appearance from the EBPOM Chicago 2020 host, Sol Aronson, tenured Professor at Duke University.

"Cognitive testing has been in the news ... there are recommendations for keeping pets mentally sound by implementing nutritional modifications, regular exercise and mental stimulation, we should certainly think about providing the same support to our geriatric patients." What does the latest research say about this vital issue? How is frailty defined? What's the clinical impact of preoperative cognitive dysfunction? Presented by Angela Bader, MD, MPH Professor of Anesthesia at Harvard Medical School and Vice Chair for Perioperative Medicine in the Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital. She is also the founding director of the Weiner Center for Preoperative Evaluation. For more on this subject check out this piece here: https://www.topmedtalk.com/poet-3-04-is-paternalism-always-bad/

Description: Indiana University researchers are studying cognitive dysfunction after chemotherapy, and environmental health researcher Gabriel Fillippelli discusses President Joe Biden's infrastructure plan to target lead pipes that threaten public health

Hello and Welcome to Dr Jones’ Veterinary Secrets PODCAST – this is episode 114! In today’s episode.. What you need to look for in choosing the right Essential Fatty Acid for your Dog or Cat, Heart Disease and Dog Food Update, Heart Remedies, plus what’s new for Cognitive Dysfunction in Pets. Dr Jones’ Veterinary Secrets is on all your favorite podcast apps, including Spotify, iTunes and Stitcher-I would sure appreciate it if you would subscribe to my podcast, and leave a review. Questions or suggestions? Feel free to post a comment about this podcast episode on the blog at www.theinternetpetvet.com  I encourage you to SIGN UP for my New FREE Webinar… What You NEED to Know about Essential Fatty Acids for Dogs and Cats… The sign up is here: http://www.theomega3supplement.com/webinar

Brain fog is really common with chronic illness, but did you know there are a ton of causes to it? There are also some ways to deal with it so it has less of an impact on your life.In this episode we talk about:what brain fog isthe causes of brain fogresearch into brain fogways to combat brain fognotice the hand mindfulness exerciseLet me know what you thought of the episode by DM-ing me or tagging me in your story on Instagram: @janeversuspain

Mental fuzziness, or “brain fog,” is a frustrating phenomenon that often occurs with arthritis and related conditions, like fibromyalgia. Listen to experts discuss some suspected causes and ways to deal with it. Visit the Live Yes! With Arthritis Podcast site to read the blog and get show notes and a full transcript: https://arthritis.org/liveyes/podcast We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started here: https://arthritisfoundation.az1.qualtrics.com/jfe/form/SV_ebqublsylCl7BIh Special Guests: Andrew Schrepf, Ph.D and Susan M. Goodman, MD.

On today's episode, we discuss canine cognitive dysfunction or better known as doggy dementia. Hope you enjoy!

This piece gets deep into a much needed discussion regarding frailty, delirium, post-operative cognitive dysfunction and brain health. Noted as one of the highlights of the year in our recent holiday specials and previously only available to attendees to the incredibly successful EBPOM Chicago 2020; go to www.ebpom.org now for more details on forthcoming events and special offers now. This piece is part two of two. This piece gets a mention "End of life decision planning in the perioperative setting: the elephant in the room?" https://academic.oup.com/bja/article/115/5/648/230412?login=true The Global Council on Brain Health is here on the American Association of Retired People's website: https://www.aarp.org/health/brain-health/global-council-on-brain-health/ This is part one of a two part piece, part two features questions from the online conference audience. Presented by Monty Mythen with Angela Bader, Professor of Anesthesia at Harvard Medical School and Vice Chair for Perioperative Medicine in the Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital, founding Director of the Weiner Center for Preoperative Evaluation, Sarah Lenz Lock, Senior Vice President for Policy and Brain Health in the American Association of Retired People's (AARP) Policy, Research and International Affairs (PRI), Executive Director of the Global Council on Brain Health, Jeanna Blitz associate professor of Anesthesiology at Duke University School of Medicine, Director of the Preoperative Anesthesia Surgical Screening (PASS) Clinic. There's also a surprise appearance from the EBPOM Chicago 2020 host, Sol Aronson, tenured Professor at Duke University.

This piece gets deep into a much needed discussion regarding frailty, delirium, post-operative cognitive dysfunction and brain health. Noted as one of the highlights of the year in our recent holiday specials and previously only available to attendees to the incredibly successful EBPOM Chicago 2020; go to www.ebpom.org now for more details on forthcoming events and special offers. This piece gets a mention "End of life decision planning in the perioperative setting: the elephant in the room?" https://academic.oup.com/bja/article/115/5/648/230412?login=true The Global Council on Brain Health is here on the American Association of Retired People's website: https://www.aarp.org/health/brain-health/global-council-on-brain-health/ This is part one of a two part piece, part two features questions from the online conference audience. Presented by Monty Mythen with Angela Bader, Professor of Anesthesia at Harvard Medical School and Vice Chair for Perioperative Medicine in the Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital, founding Director of the Weiner Center for Preoperative Evaluation, Sarah Lenz Lock, Senior Vice President for Policy and Brain Health in the American Association of Retired People's (AARP) Policy, Research and International Affairs (PRI), Executive Director of the Global Council on Brain Health, Jeanna Blitz associate professor of Anesthesiology at Duke University School of Medicine, Director of the Preoperative Anesthesia Surgical Screening (PASS) Clinic. There's also a surprise appearance from the EBPOM Chicago 2020 host, Sol Aronson, tenured Professor at Duke University.

Why is my 13 y.o. dog seeming so confused by every day tasks? She doesn't seem to recognize me anymore and went to the window to be let outside. Then she seemed to get lost on our usual walk and became quite anxious. She is pacing all night long and then sleeps throughout the day. She's never had an accident, and now urinated on the dining room rug twice last week! Sound familiar? According to Bronwyn Riggs, VMD, DACVIM (Neurology), perhaps it's cognitive dysfunction that is responsible for changes in her behavior, disorientation, and confusion. The brain experiences age-related degenerative changes just like muscles. Impairment of memory and learning with age exists across all species. Factors such as genetics, diet, environment, lifestyle, and metabolic diseases contribute to susceptibility. Although there is no cure, cognitive decline can be managed with enrichment, behavior modification, targeted nutrition, medications, and certain supplements. To exercise their brain, you can teach your old dog new tricks!  Links:Found out more about Thundershirts to decrease your pet's anxiety.For some great puzzle toys and brain games, check this out!!To learn more about Dr. Riggs and her place of employment, click here.DisclaimerThe contents of the PetAbilityTM  podcast are for informational purposes only.   The host(s) and their guests make no claims, warranties or representations about the content of these podcasts, or the accuracy, completeness or timeliness of their content. The opinions expressed are those of the host(s) and their guests. Discussion about any third party products or services are not intended to be endorsements or suggest any relationship or association between PetAbility and any other person or entity.  The host(s) and guests are not responsible or liable for any damage, injury, mistake, misinterpretation, or misuse of the contents of the podcasts or any related materials. Furthermore, this podcast and any associated materials are not a substitute for professional veterinary care.Support the show (https://www.paypal.com/donate?hosted_button_id=Q3T26JAY5L3S8)

Hosts Bill McBain and Tiffany Rennick on talk about Presidential Pets and Cognitive Dysfunction Our Breed of the Week section:. Rabbits The Urban Zoo is brought to you by VCA Canada and is hosted by Dr. Tiffany Rennick and Bill McBain every Wednesday at 1 p.m. EST.

In this episode of The Health Made SImple Show, Dr. Bart is joined by Dr. Ryan Wohlfert to discuss the present and future of brain health. Dr. Ryan Wohlfert has reached hundreds of thousands of people worldwide helping them improve their brain function, energy levels, and overall performance!  Today these two discuss how big of a problem neurological disease can be, why conventional medical treatment has failed our brains, the first step to determine your Cognitive Baseline, and many other essential brain health concepts!   - Dr. Ryan's Story   This episode begins with Dr. Ryan expressing his personal experience with a neurological disorder that developed in middle school.  This experience completely changed the trajectory of Dr. Ryan's life, as it sent him down a path to uncover the importance of taking care of the brain and the importance of developing a superhuman lifestyle.   - What is the Impact of Neurological Disorders?   Neurological disorders are more common than many may think. For example, migraines are a neurological disorder that one out of every six people in the world experience. Neurological diseases are the number one cause of health deterioration, as our age progresses. This can range from migraines to even strokes, MS, and Alzheimer's.   - What should we consider about Alzheimer's?   Alzheimer's is not just an old person's disease. People are showing signs in their 30's, 40's, and 50's.  Just in America, 72 million people are experiencing Alzheimer's to some degree.    Pre-Alzheimer's can be seen 20-30 years before a diagnosis is ever given.   Alzheimer's is not a one-factor issue. Multiple considerations lead to its development.  It is not caused by plaque development in our brain, however, that is a sign that it is developing.   - What is Pre-Alzheimer's?   What are the steps leading to Alzheimer's? Pre-Alzheimer's can be seen when you begin to forget your keys or you walk into a room and forget why you are there. It is mild symptoms of mental fog and forgetfulness The next step for this is that you begin to have subjective cognitive decline. You notice that your mind is not firing as quickly as it had in the past and you're just focussed on getting by. Following this is cognitive impairment. At this point, your family and friends begin to notice your cognitive decline and it is apparent your mind is deteriorating Lastly, is a diagnosis of Alzheimer's. At this point, the rapid decline begins.   - How Can We Work to Prevent Neurological Disorders?   Sleep is one of the most effective ways to overcome the development of Alzheimer's.  We must be aware of our sugar intake, aiming to keep it very low and consistently practice clean eating. What we consume ends up making its way to our brain.  Heavy metals are one of the leading causes of neurological disorders, as they prevent the brain cells from absorbing nutrients. We must take steps to eliminate them from our diet.   - How Can We Work to Prevent Neurological Disorders?   Sleep is one of the most effective ways to overcome the development of Alzheimer's. We must be aware of our sugar intake, aiming to keep it very low and consistently practice clean eating. What we consume ends up making its way to our brain. Heavy metals are one of the leading causes of neurological disorders, as they prevent the brain cells from absorbing nutrients. We must take steps to eliminate them from our diet.   - What Are EMFs and How Do They Impact us?   EMF's are electromagnetic forces that are emitted from anything that contains electricity. Computers, phones, and televisions all emit these signals that are impacting our brains constantly. A good way to combat this is distance. Do not plug your phone in next to your bed. Make sure there is distance between you and electronics when you are somewhere for an extended time. Another solution is to purchase an EMF blocker for outlets near your bed to reduce their impact on you. The issue with EMF's is that they breach the blood-brain barrier and damage the cells within our brain, similar to heavy metals and biotoxins.   - What is the 6-Pack of Brain Health?   Focus What is your mindset on your health? Are you growth minded?   Food Anything you use to fuel your body from the food you eat to essential oils and lotion.   Fitness Movement and exercise are essential to get your nutrients up to the brain.   Function All function comes from the mind through the spinal cord. A strong posture is essential for brain health.   Refresh Sleep is essential! You can learn more about this on Dr. Bart's in-depth talk below    Faith A belief in the unseen and a purpose in your life is essential to developing a healthy mind.    And to Make it an 8-Pack Fun & Family These two are essential motivators that help keep us young and living lives of purpose, improving our mental health and cognitive function.   - How Do Head Traumas Impact our Brain Function?   The brain is the most sensitive, fragile, and important organ that you have in your body.  Trauma, especially consistent trauma such as a soccer player heading a ball or a football player, accelerates the damage. The brain is the only organ fully protected by a shell of bone. This is for a reason!    - How to Combat and Prepare for Cognitive Dysfunction   Dr. Ryan and his team have developed a cutting-edge technique to determine if you are or are expected to be at risk for cognitive deterioration.   This three-minute questionnaire will gauge if you qualify for a longer 30-minute consultation with members of their team, free of charge! The link to this remarkable opportunity is listed below Brain Health Quiz: https://www.mioshealth.com/start-today   - General Questions Concerning Brain Health   How are mental health and brain health-related? Mental health is a brain health issue.    Issues such as anxiety, depression, schizophrenia, and even PTSD are directly related to the health of our minds.   Can cannabis oil affect mental health disorders? Yes, but not all of the way. We must seek multifaceted treatments to ensure a full version of mental and physical health. The goal is not to be dependent on anything! We need to look at our fitness, diet, and general lifestyle that we are living.   Where should we start? It is essential to develop an all-encompassing approach to monitoring our health.  Consider your goals and develop a customized plan that includes all aspects of your health.   What are daily supplements that could impact brain health? Multiple supplements can help out overall health and our brain health! For an in-depth look at how to effectively use supplements look at Dr. Bart's previous talk on brain health at the link below!    - Making Health Simple   Final Tip to Becoming SuperHuman Make smoothies!!!!! On totalhealthspine.com you can find great recipes for smoothies that will improve your overall health. Get your superhuman smoothie recipe here: http://totalhealthspine.com/   - What's Next?   We have put together a dashboard of all of Dr. Bart's videos, based on health topics, in our Level-Up Health Membership. This library of health content is low cost, so we can help you on your journey to becoming superhuman!  Not only is it extensive, but it will continue to expand with new videos each month. Also, you will have the opportunity to share these videos with your friends and family!   -- Medically reviewed and written by: Dr. Bart Precourt Founder of  The Health Made Simple Show Doctor of Chiropractic Register for the Health Made Simple Show If you are interested in registering for the Health Made Simple Show please visit http://www.healthmadesimple.com

Lori begins the show with a discussion of the myriad problems with testing of consumer products like cosmetics on animals. Despite rapid advances in technology that is capable of replacing animal testing, antiquated and cruel methods still are often employed in the US and Canada. Notably, the FDA does not require animal testing and 40 […]

Dr. John DeLuca, Senior Vice President for Research and Training at Kessler Foundation talks about his latest peer reviewed article “Treatment and management of cognitive dysfunction in patients with multiple sclerosis” which was published on May 5, 2020 in the journal Nature Reviews Neurology. Funding source: Kessler Foundation and the University of Alabama at Birmingham Read more about Dr. DeLuca and his research at https://kesslerfoundation.org/aboutus/John%20DeLuca For more information about this study, check out the press release https://kesslerfoundation.org/press-release/experts-analyze-options-treating-multiple-sclerosis-related-cognitive-impairment or at https://www.nature.com/articles/s41582-020-0355-1 Co-authors: Nancy D. Chiaravalloti (https://kesslerfoundation.org/aboutus/Nancy%20Chiaravalloti) Brian M. Sandroff (https://kesslerfoundation.org/about-us/foundation-staff/brian-m-sandroff-phd) Follow us on Facebook, Twitter, and Instagram. Listen to us on Apple Podcasts, Spotify, SoundCloud, or wherever you get your podcasts. This podcast was recorded on Monday, October 5, 2020 remotely and was edited and produced by Joan Banks-Smith, Creative Producer for Kessler Foundation

"Cognitive testing has been in the news ... there are recommendations for keeping pets mentally sound by implementing nutritional modifications, regular exercise and mental stimulation, we should certainly think about providing the same support to our geriatric patients." What does the latest research say about this vital issue? How is frailty defined? What's the clinical impact of preoperative cognitive dysfunction? Presented by Angela Bader, MD, MPH Professor of Anesthesia at Harvard Medical School and Vice Chair for Perioperative Medicine in the Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital. She is also the founding director of the Weiner Center for Preoperative Evaluation. For more on this subject check out this piece here: https://www.topmedtalk.com/poet-3-04-is-paternalism-always-bad/

Welcome back to EndoPod! We are very glad to be starting back and hope you didn't miss us too much. In this episode, Hepsi (3rd year MBChB student) is covering the potential link between diabetes and decline in mental function leading to conditions such as dementia. Is there any scope for new treatments with this information? Listen in to find out! Aberdeen University Endocrinology Society are a student lead organisation. All information provided in this podcast are intended for educational purposes. This podcast is not intended to replace the advice of a qualified health professional. The students involved in the making of this episode are in the 3rd year of their medical education (Hepsi Xavier). References: https://care.diabetesjournals.org/content/40/4/461 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085321/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528145/ https://www.idf.org/aboutdiabetes/what-is-diabetes/facts-figures.html http://academics.wellesley.edu/Biology/Concepts/Html/neurogenesiswhat.html https://www.healthline.com/health/oxidative-stress https://www.diabetes.org/diabetes/medication-management/blood-glucose-testing-and-control/hypoglycemia https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/1696172 https://www.news-medical.net/health/Alzheimers-tangles-and-plaques-whats-the-difference.aspx

Welcome back to EndoPod! We are very glad to be starting back and hope you didn't miss us too much. In this episode, Hepsi (3rd year MBChB student) is covering the potential link between diabetes and decline in mental function leading to conditions such as dementia. Is there any scope for new treatments with this information? Listen in to find out! This is a simplified version for our listeners without a scientific/medical background. Aberdeen University Endocrinology Society are a student lead organisation. All information provided in this podcast are intended for educational purposes. This podcast is not intended to replace the advice of a qualified health professional. The students involved in the making of this episode are in the 3rd year of their medical education (Hepsi Xavier). References: https://care.diabetesjournals.org/content/40/4/461 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085321/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528145/ https://www.idf.org/aboutdiabetes/what-is-diabetes/facts-figures.html http://academics.wellesley.edu/Biology/Concepts/Html/neurogenesiswhat.html https://www.healthline.com/health/oxidative-stress https://www.diabetes.org/diabetes/medication-management/blood-glucose-testing-and-control/hypoglycemia https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/1696172 https://www.news-medical.net/health/Alzheimers-tangles-and-plaques-whats-the-difference.aspx

Whether you call it brain fog, cog-fog, or you don't happen to have a name for it, cognitive dysfunction affects more than half of all the people with MS.   Joining me once again is Dr. Meghan Beier, a Rehabilitation Neuropsychologist and Assistant Professor of Physical Medicine at the Johns Hopkins University School of Medicine. Dr. Beier specializes in cognitive rehabilitation and neuropsychological assessment and intervention and she's back to answer more of our questions about managing the cognitive issues typically associated with MS.     We're also talking about Kesimpta (ofatumumab), the high-efficacy b-cell disease-modifying therapy that just received FDA approval.   We'll tell you about the case study of a patient who lost their vaccination immunity to the Varicella-Zoster virus (causes chickenpox & shingles) after receiving their first Ocrevus infusion.   We'll give you the details about the generic for Tecfidera that's going to be available in just a few weeks. And we'll tell you why the U.S. Department of Justice is suing Teva, the manufacturer of Copaxone.   We'll share all the details and let you know where to register for the National MS Society's Black MS Experience Summit.   And we'll tell you how a research team from Facebook (yup -- you read that right!) and New York University is hoping to speed up MRI exams.   We have a lot to talk about! Are you ready for RealTalk MS??! We're trending!  :22 FDA approves ofatumumab (Kesimpta) for treating relapsing-remitting MS and active secondary-progressive MS  3:53 Patient loses vaccination immunity for Varicella-Zoster virus after Ocrevus infusion    5:44 Generic for Tecfidera will be available in September  8:25 U.S. Department of Justice sues Coaxone manufacturer, Teva  9:18 National MS Society to convene the Black MS Experience Summit  12:24 Facebook & New York University research team develop artificial intelligence technology that will speed up MRI exams  13:26 My Interview with Dr. Meghan Beier  15:48 Share this episode  29:38 Leave a rating & review  29:58 Please Support the National MS Society COVID-19 Response Fund  30:22 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email:  https://realtalkms.com/156 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.comPhone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Give RealTalk MS a Rating and Review National MS Society's Ask An MS Expert Video Replay What You Need to Know About Coronavirus (COVID-19) Varicella-Zoster Immunity Loss in Multiple Sclerosis Patient Treated with Ocrelizumab National MS Society Black MS Experience Summit National MS Society COVID-19 Response Fund Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Download the RealTalk MS App for Android Give RealTalk MS a Rating and Review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 156 Hosted By: Jon Strum Guests: Dr. Meghan Beier Tags: MS, MultipleSclerosis, MSResearch, MSSociety, Tecfidera, Ocrevus, Kesimpta, Ofatumumab, RealTalkMS Privacy Policy

In this episode, I attempt to re-enact Donald Trump's now infamous cognitive test, where he is challenged on: his ABCs, drawing shapes, counting, and naming animals most 2-year-olds know. If, after hearing this, you don't think he's a genius, then there's something seriously wrong with... Just kidding, you'd be right.Bookshttps://www.amazon.com/Craig-Rozniecki/e/B00JBQ95LO Bloghttps://thekind-heartedsmartaleck.blogspot.com/ Twitterhttps://twitter.com/CraigRozniecki

Commentary by Dr. Valentin Fuster

Dr. Emma Foster discusses her article, "Antiepileptic drugs are not independently associated with cognitive dysfunction".

Moderator: BobbieJean Sweitzer, M.D. Participants: Lori A. Daiello, Pharm.D., Sc.M., and Jeffrey N. Browndyke, Ph.D. Articles Discussed: Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence The Devil Is in the Details: Comparison of Postoperative Delirium and Neurocognitive Dysfunction Transcript  

In this episode, guest host Dr. David Poetker speaks with Dr. Zach Soler. They will discuss the article: Effects of endoscopic sinus surgery on objective and subjective measures of cognitive dysfunction in chronic rhinosinusitis. Read the article in International Forum of Allergy and Rhinology Listen and subscribe for free on Apple Podcasts , Google Play […]

Objective: Dementia is a common and feared aspect of Parkinson's disease but there are no robust predictors of cognitive outcome. Visuoperceptual deficits are linked to risk of dementia in Parkinson's disease but whether they predict cognitive change is not known, and the neural substrates of visuoperceptual dysfunction in Parkinson's have not yet been identified. Methods: We compared patients with Parkinson's disease and unaffected controls who underwent BOLD fMRI while performing our previously validated visuoperceptual task and tested how functional connectivity between task‐specific regions and the rest of the brain differed between patients who performed well and poorly in the task. Results: We show that task performance at baseline predicts change in cognition in Parkinson's disease after 1 year. Our task‐based fMRI study showed that the performance in this task is associated with activity in the posterior cingulate cortex/precuneus. We found that functional connectivity between this region and dorsomedial prefrontal cortex was reduced in poor performers compared with good performers of this task. Interpretation: Our findings suggest that functional connectivity is reduced between posterior and anterior hubs of the default mode network in Parkinson's patients who are likely to progress to worsening cognitive dysfunction. Our work implicates posterior default mode nodes and their connections as key brain regions in early stages of dementia in Parkinson's disease. Weil RS, Winston JS, Leyland LA, et al. Neural correlates of early cognitive dysfunction in Parkinson's disease. Ann Clin Transl Neurol. 2019;6(5):902–912. Published 2019 Mar 28. doi:10.1002/acn3.767. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Sections of the Abstract and Introduction are presented in the Podcast. Link to the full-text article:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529983/

Dr Trepheena Hunter is a behavioural veterinarian with a special interest in the mental health and well-being of shelter animals. She worked for several years as the principal behaviourist in the Lost Dogs Home in Melbourne, Victoria, before branching into private practice. Trepheena and I discuss her experiences working in this shelter, and the passion she developed for preparing dogs mentally for successful re-homing, before diving into the interesting topic of cognitive dysfunction in dogs and cats.  Topics discussed include: The high prevalence and extremely common under-diagnosis of cognitive dysfunction in dogs and cats  The importance of establishing routine screening questionnaires as part of history taking in consultations, looking particularly for ongoing progressive change  The useful acronym, "DISHAA" for identifying the classic symptoms of cognitive dysfunction  How cognitive dysfunction can be easily confused with other common conditions in older animals  The pathophysiology of the condition, and the similarities to human Alzheimer's Disease  The importance of early treatment interventions and prevention and what a treatment plan may look like, including nutritional, environmental and brain stimulating approaches  You can find Dr Hunter at Wild Things Veterinary Behaviour Services: reachable at wildthingsvbs.com.au, info@wildthingsvbs.com.au or 0414 588 586.

Do you know much about the cognitive effects of benzodiazepines and Z-drugs? Perhaps you should. Memory loss, cognitive dysfunction, and intrusive memories are all possible symptoms of benzo use and withdrawal. In today's episode, we talk about the damage benzodiazepines and Z-drugs can inflict on our mental capacity. We also hear a benzo story from England, answer a question about GABA receptors, and learn what it really feels like to heal. BTW, it feels good. https://www.easinganxiety.com/post/benzo-brain-cognitive-dysfunction-and-memory-loss-in-withdrawal-bfp017Video ID: BFP017 Chapters 00:00 Introduction11:42 Mailbag13:39 Benzo News15:50 Benzo Story20:33 FEATURE: Benzo Brain40:54 Moment of Peace  Resources The following resource links are provided as a courtesy to our listeners. They do not constitute an endorsement by Easing Anxiety of the resource or any recommendations or advice provided therein. BENZO NEWS TECH INSIDER: “What Happens When You Take Xanax?” (VIDEO)BIC: “Why Prescribed Benzo Patients Shouldn't Go to Detox or Rehab,” by Nicole LambersonBENZO FREE PODCAST – Episode #16: “The Assault on Our Senses: Benzo Withdrawal Symptoms of the Eyes, Ears, Nose, and Mouth”MPR: “FDA: Boxed Warning, Contraindication Added to Several Insomnia Medications,” by Diana ErnstHEALTH EUROPA: “Newly uncovered gene mutation has the ability to reduce fear and anxiety”BENZO FREE: “The Missing Message: New FDA Boxed Warning for Z-drugs,” by D E Foster FEATURE: Benzo Brain Ashton, C. Heather. Benzodiazepines: How They Work and How to Withdraw (aka The Ashton Manual). 2002. Accessed April 13, 2016. http://www.benzo.org.uk/manual.Barker, M.J., K.M. Greenwood, M. Jackson, S.F. Crowe. “Cognitive Effects of Long-Term Benzodiazepine Use: A Meta-Analysis.” CNS Drugs 18(1)(2004):37-48. Accessed March 6, 2017. https://www.ncbi.nlm.nih.gov/pubmed/14731058.Doyle, Chase, “Benzodiazepine Exposure Can Predict Delirium in Critically Ill Children,” Anesthesiology News, October 13, 2016, accessed October 13, 2016, http://www.anesthesiologynews.com/Clinical-Anesthesiology/Article/10-16/Benzodiazepine-Exposure-Can-Predict-Delirium-in-Critically-Ill-Children/38055.Foster, D E. Benzo Free: The World of Anti-Anxiety Drugs and the Reality of Withdrawal. Erie, Colorado: Denim Mountain Press, 2018. https://easinganxiety.com/book. Guina, Jeffrey, and Brian Merrill. “Benzodiazepines I: Upping the Care on Downers: The Evidence of Risks, Benefits and Alternatives.” Journal of Clinical Medicine 7(2)(February 2018):17. Accessed July 12, 2018. doi: 10.3390/jcm7020017.Gorenstein, C., M. A. Bernik and S. Pompéia. “Differential Acute Psychomotor and Cognitive Effects of Diazepam on Long-Term Benzodiazepine Users.” International Clinical Psychopharmacology 9(3)(1994):145-53. Accessed March 6, 2017. doi:10.1097/00004850-199409000-00002.Hunt, Liz and Glenn Frankel, “Britain Takes Halcion Sleeping Pills off the Market,” Washington Post, October 3, 1991, accessed April 8, 2018, https://www.washingtonpost.com/archive/politics/1991/10/03/britain-takes-halcion-sleeping-pills-off-the-market/21d83dc2-2260-440d-96d1-7da13ceb0198/?utm_term=.e008daa4566c.Tata, P.R., J. Rollings, M. Collins, A. Pickering and R. R. Jacobson. “Lack of Cognitive Recovery Following Withdrawal from Long-Term Benzodiazepine Use.” Psychological Medicine 24(1)(February 1994):203-13. Accessed April 15, 2018. doi:10.1017/S0033291700026969.U.S. Department of Veteran's Affairs (VA/DoD). PTSD: National Center for PTSD: Use of Benzodiazepines for PTSD in Veterans Affairs. Accessed June 21, 2017. https://www.ptsd.va.gov/professional/treat/txessentials/benzos_va.asp.  Introduction In today's intro, I was feeling good — and I shared that with the listeners. My healing has been progressing and I'm now, ever so slowly, getting my life back. Actually, I'm getting a better life than I had. And I wanted to share that with the listeners as a reminder that healing does take place and there are good things on the other side. I also talked about limited the length of the podcast episodes down to 45 minutes or so. I felt that they were getting too long and I explained that this might include making some sections periodic.  Mailbag This is where we share questions and comments which were discussed: QUESTION: Do Your GABA Receptors Heal During Titration?This comment was from Kathy in Colorado, USA. She wanted to know if her GABA receptors were healing during titration (or taper). I told her they probably were and that when you start reducing the amount of drug in your body, homeostasis kicks in again and starts the rebalancing effect— but this process can take a very long time.  Benzo Story Today's story was from a Nancy in England.  Feature Today's featured topic: Benzo Brain: Cognitive Dysfunction and Memory Loss in Withdrawal. This was the fifth installment in our 14-part series on benzo withdrawal symptoms. It focused on cognitive effects of benzo withdrawal which included cognitive dysfunction, memory loss, and intrusive memories. I discussed each symptom at length and included several references which can be seen in our links above  The PodcastThe Benzo Free Podcast provides information, support, and community to those who struggle with the long-term effects of anxiety medications such as benzodiazepines (Xanax, Ativan, Klonopin, Valium) and Z-drugs (Ambien, Lunesta, Sonata). WEBSITE: https://www.easinganxiety.comMAILING LIST: https://www.easinganxiety.com/subscribe YOUTUBE: https://www.youtube.com/@easinganx DISCLAIMERAll content provided by Easing Anxiety is for general informational purposes only and should never be considered medical advice. Any health-related information provided is not a substitute for medical advice and should not be used to diagnose or treat health problems, or to prescribe any medical devices or other remedies. Never disregard medical advice or delay in seeking it. Please visit our website for our complete disclaimer at https://www.easinganxiety.com/disclaimer. CREDITSMusic provided / licensed by Storyblocks Audio — https://www.storyblocks.com Benzo Free Theme — Title: “Walk in the Park” — Artist: Neil Cross PRODUCTIONEasing Anxiety is produced by…Denim Mountain Presshttps://www.denimmountainpress.com ©2022 Denim Mountain Press – All Rights Reserved

Do you know much about the cognitive effects of benzodiazepines and Z-drugs? Perhaps you should. Memory loss, cognitive dysfunction, and intrusive memories are all possible symptoms of benzo use and withdrawal.In today's episode, we talk about the damage benzodiazepines and Z-drugs can inflict on our mental capacity. We also hear a benzo story from England, answer a question about GABA receptors, and learn what it really feels like to heal. BTW, it feels good. Welcome to Episode #17 Today we focus on the withdrawal symptoms associated with cognition. These include cognitive dysfunction, memory loss, and intrusive memories. We talk about the causes and provide a few tips on dealing with these drawn-out group of symptoms. We also hear a benzo story from England learn about when GABA receptors start to heal. But first, let's list the resources used in this episode, and then we'll dive deeper into the content of episode 17. Episode Resources The following resource links are provided as a courtesy to our listeners. They do not constitute an endorsement by Benzo Free of the resource or any recommendations or advice provided therein. BENZO NEWSTECH INSIDER: "What Happens When You Take Xanax?" (VIDEO)BIC: "Why Prescribed Benzo Patients Shouldn't Go to Detox or Rehab," by Nicole LambersonBENZO FREE PODCAST - Episode #16: "The Assault on Our Senses: Benzo Withdrawal Symptoms of the Eyes, Ears, Nose, and Mouth"MPR: "FDA: Boxed Warning, Contraindication Added to Several Insomnia Medications," by Diana ErnstHEALTH EUROPA: "Newly uncovered gene mutation has the ability to reduce fear and anxiety"BENZO FREE: "The Missing Message: New FDA Boxed Warning for Z-drugs," by D E Foster FEATURE: Benzo BrainAshton, C. Heather. Benzodiazepines: How They Work and How to Withdraw (aka The Ashton Manual). 2002. Accessed April 13, 2016. http://www.benzo.org.uk/manual.Barker, M.J., K.M. Greenwood, M. Jackson, S.F. Crowe. "Cognitive Effects of Long-Term Benzodiazepine Use: A Meta-Analysis." CNS Drugs 18(1)(2004):37-48. Accessed March 6, 2017. https://www.ncbi.nlm.nih.gov/pubmed/14731058.Doyle, Chase, "Benzodiazepine Exposure Can Predict Delirium in Critically Ill Children," Anesthesiology News, October 13, 2016, accessed October 13, 2016, http://www.anesthesiologynews.com/Clinical-Anesthesiology/Article/10-16/Benzodiazepine-Exposure-Can-Predict-Delirium-in-Critically-Ill-Children/38055.Foster, D E. Benzo Free: The World of Anti-Anxiety Drugs and the Reality of Withdrawal. Erie, Colorado: Denim Mountain Press, 2018. http://www.benzofree.org/book.Guina, Jeffrey, and Brian Merrill. “Benzodiazepines I: Upping the Care on Downers: The Evidence of Risks, Benefits and Alternatives.” Journal of Clinical Medicine 7(2)(February 2018):17. Accessed July 12, 2018. doi: 10.3390/jcm7020017.Gorenstein, C., M. A. Bernik and S. Pompéia. "Differential Acute Psychomotor and Cognitive Effects of Diazepam on Long-Term Benzodiazepine Users." International Clinical Psychopharmacology 9(3)(1994):145-53. Accessed March 6, 2017. doi:10.1097/00004850-199409000-00002.Hunt, Liz and Glenn Frankel, "Britain Takes Halcion Sleeping Pills off the Market," Washington Post, October 3, 1991, accessed April 8, 2018, https://www.washingtonpost.com/archive/politics/1991/10/03/britain-takes-halcion-sleeping-pills-off-the-market/21d83dc2-2260-440d-96d1-7da13ceb0198/?utm_term=.e008daa4566c.Tata, P.R., J. Rollings, M. Collins, A. Pickering and R. R. Jacobson. "Lack of Cognitive Recovery Following Withdrawal from Long-Term Benzodiazepine Use." Psychological Medicine 24(1)(February 1994):203-13. Accessed April 15, 2018. doi:10.1017/S0033291700026969.U.S. Department of Veteran's Affairs (VA/DoD). PTSD: National Center for PTSD: Use of Benzodiazepines for PTSD in Veterans Affairs. Accessed June 21, 2017. https://www.ptsd.va.gov/professional/treat/txessentials/benzos_va.asp. BENZO FREE LINKSWebsitePodcast Home PageFeedback FormDisclaimer Podcast Summary

Eileen Anderson (of the award winning blog, eileenanddogs) joins Julie Fudge Smith and Colleen Pelar to discuss her book, Remember Me? Loving and Caring for a Dog with Canine Cognitive Dysfunction. Learn about the symptoms and signs of canine dementia and how you can make your dog's life safe and comfortable.   For more information and show notes, please see: Your Family Dog

Join host Jon Strum as he breaks down the latest multiple sclerosis news. Talking about the amazing MS research that’s currently being done in laboratories around the world — and talking to some of the brilliant neuroscientists who are conducting that research! Listen to host Jon Strum as he interviews Dr. John DeLuca, the Senior Vice-President of Research & Training at the Kessler Foundation, and the co-author of the just-published report that details this important set of new guidelines. Thanks to Jon Strum and RealTalk MS for allowing us to post this podcast. For more information about Jon Strum and RealTalk MS, go to http://realtalkms.com

Cognitive dysfunction can profoundly affect people living with MS, yet it's frequently overlooked and left untreated. That's why the National MS Society convened a working group of world-class experts to explore how cognitive dysfunction was being assessed and to develop a set of guidelines designed to improve the process of cognitive screening and management in MS care.      My guest is Dr. John DeLuca, the Senior Vice-President of Research & Training at the Kessler Foundation, and the co-author of the just-published report that details this important set of new guidelines.   We're also making an exciting announcement with the Accelerated Cure Project for MS about the RealTalk MS podcast. We're talking about how you can prepare for next week's midterm election in the U.S., we'll tell you how the Federal Trade Commission went after 2 crooked stem cell clinics that claimed they were curing MS, we'll give you a heads-up about MS stem cells that really are heading for outer space, and you'll hear about an investment that the National MS Society made in some exciting cutting-edge commercial biotech research.   We have a lot to talk about! Are you ready for RealTalk MS?! ___________ Some Exciting News About RealTalk MS  2:16 How You Can Prepare to Vote in the U.S. Next Week  4:10 2 Phony Stem Cell Clinics Caught Defrauding Patients  10:09 MS Stem Cells Are Headed for Outer Space  14:22 National MS Society Invests in Cutting-Edge Commercial BioTech Research  16:20  Interview with Dr. John DeLuca  17:58 ___________ LINKSIf your podcast app doesn’t allow you to click on these links, you’ll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Download the RealTalk MS App for iOS Download the RealTalk MS App for Android iConquerMS RealTalk MS Congressional Report Card FTC Complaint Against Dr. Bryn Jarald Henderson's Stem Cell Clinics Recommendations for Cognitive Screening and Management in Multiple Sclerosis Care Give RealTalk MS a Rating & Review ___________ Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 62 Hosted By: Jon Strum Guest: Dr. John DeLuca Tags: MS, MultipleSclerosis, MSActivist, Election2018, iConquerMS, KesslerFdn, RealTalkMS

Do you have sleep apnea? Do you snore? Do you wake up in the middle of the night and can't get your brain to "stop working"? Learn all the tips on how to prevent and avoid all these issues in this episode. Share with those you love. Also join us on our master class, September 7th by clicking HERE ... It's FREE, and all attendees get a complimetary cognitive assessment from Cambridge Brain Sciences!

Peter is back from Las Vegas, where he covered this year’s SuperZoo, the huge pet products trade show. He shares his impressions with Lori, admitting it’s just too much to do in one day. In upcoming shows, we will be reviewing our favorite products, many of which are being tested by our own dogs and […]

Eileen Anderson is author of 'Remember Me? Loving and Caring for a Dog with Canine Cognitive Dysfunction'. She also frequently blogs and makes videos on the topics of dog training and learning theory.

Co-hosts Dr. Roger Welton and Dr. Karen Louis indepthly discuss the all too often unrecognized disease canine cognitive dysfunction, otherewise known as dog dementia.  Canine cognitive dysfunction commonly affects senior age dogs and because of poor awareness of the disease, it all too often goes unrecognized by dog owners and even veterinarians.  Dr. Roger and Dr. Karen discuss the signs of dementia in dogs, why it is important to recognize the disease as early as possible, and what treatment options are available to manage the disease.  E-mail comments to be shared on the air to: comments@web-dvm.net.  For more content from Dr. Roger and Dr. Karen, visit their respective blogs at Web-DVM.net and VetChick.com.

Understanding Depression and Cognitive Dysfunction After A Diagnosis of TM, NMO, and ADEM

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service on Canine Cognitive Dysfunction Syndrome (CDS) or Canine Cognitive Dysfunction (CCD); these terms are often used interchangeably. In Part 3 of 3, we discuss medications and their role in the treatment of CCD.

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service on Canine Cognitive Dysfunction Syndrome (CDS) or Canine Cognitive Dysfunction (CCD); these terms are often used interchangeably. In Part 3 of 3, we discuss medications and their role in the treatment of CCD.

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service on Canine Cognitive Dysfunction Syndrome (CDS) or Canine Cognitive Dysfunction (CCD); these terms are often used interchangeably. In Part 2 of 3, we discuss diet and supplements and their role in the treatment of CCD.

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service on Canine Cognitive Dysfunction Syndrome (CDS) or Canine Cognitive Dysfunction (CCD); these terms are often used interchangeably. In Part 2 of 3, we discuss diet and supplements and their role in the treatment of CCD.

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service on Canine Cognitive Dysfunction Syndrome (CDS) or Canine Cognitive Dysfunction (CCD); these terms are often used interchangeably. With our aging pet population, we veterinarians are seeing more behavioral problems in dogs (typically over 9 years). In current studies, 22-28% of elderly dogs showed at least one sign of CDS. So, what should we do? We want to make sure to monitor our patients for DISHA, which stands for:

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service on Canine Cognitive Dysfunction Syndrome (CDS) or Canine Cognitive Dysfunction (CCD); these terms are often used interchangeably. With our aging pet population, we veterinarians are seeing more behavioral problems in dogs (typically over 9 years). In current studies, 22-28% of elderly dogs showed at least one sign of CDS. So, what should we do? We want to make sure to monitor our patients for DISHA, which stands for:

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service discusses cognitive dysfunction in dogs and cats. Dr. Radosta discusses how to implement a simple, one-page cognitive dysfunction quiz that can be used by veterinary clinics for pet owners to test for it. This VetGirl podcast specifically discusses DISHA, which is short for Disorientation, Interaction, Sleep Wake-Cycle, House-training, and Activity/Anxiety/Aggression level changes.

Today's VETgirl online veterinary continuing education podcast is by veterinary behaviorist, Dr. Lisa Radosta from Florida Veterinary Behavior Service discusses cognitive dysfunction in dogs and cats. Dr. Radosta discusses how to implement a simple, one-page cognitive dysfunction quiz that can be used by veterinary clinics for pet owners to test for it. This VetGirl podcast specifically discusses DISHA, which is short for Disorientation, Interaction, Sleep Wake-Cycle, House-training, and Activity/Anxiety/Aggression level changes.

Cognitive Dysfunction in Depressed Patients Andrew Nierenberg, MD

Dr. Roger reports on a common and eventually debilitating brain condition of dogs called canine cognitive dysfunction.  Dr. Roger explains the importance of early recognition and comprehensive nutritional, supplemental management of the disease, as well as medical management of advanced cases.  E-mail questions/comments to be addressed live on the air to comments@web-dvm.net.  

MDS presents the latest research and findings from the field of Movement Disorders. Abstracts of articles from the Society Journal, Movement Disorders, are taken from the September 2013 (Vol. 28, Issue 10) issue.

Anthony Zietman talks with author Nadia Laack about this game-changing research

"Pharmacological Approaches to Fatigue and Cognitive Dysfunction in Depression" was given by Maurizio Fava at The 4th Annual Massachusetts General Hospital Colloquium on Depression in Boston, Massachusetts on June 2nd, 2012.

Background: Endocannabinoids (ECs) are rapidly acting immune-modulatory lipid-signaling molecules that are important for adaptation to stressful and aversive situations. They are known to interact with glucocorticoids and other stress-responsive systems. Maladaptation to acute or chronic stress represents a major risk factor for the development of psychiatric disorders. In the present study, we administered stress doses of hydrocortisone in a prospective, randomized, placebo-controlled double-blind study in patients undergoing cardiac surgery (CS) to examine the relationship between the use of glucocorticoids, plasma EC levels, and the occurrence of early postoperative cognitive dysfunction (delirium) and of later development of depression. Methods: We determined plasma levels of the ECs anandamide and 2-arachidonoylglycerol (2-AG) in CS patients of the hydrocortisone (n=56) and the placebo group (n=55) preoperatively, at postoperative day (POD) 1, at intensive care unit discharge, and at 6 months after CS (n=68). Postoperative delirium was diagnosed according to Diagnostic and Statistical Manual of the American Psychiatric Association IVth Edition (DSM-IV) criteria, and depression was determined by validated questionnaires and a standardized psychological interview (Structured Clinical Interview for DSM-IV). Results: Stress doses of hydrocortisone did not affect plasma EC levels and the occurrence of delirium or depression. However, patients who developed delirium on POD 1 had significantly lower preoperative 2-AG levels of the neuroprotective EC 2-AG (median values, 3.8 vs. 11.3 ng/ml; p=0.03). Preoperative 2-AG concentrations were predictive of postoperative delirium (sensitivity=0.70; specificity=0.69; cutoff value=4.9 ng/ml; receiver operating characteristic curve area=0.70; 95% confidence interval=0.54-0.85). Patients with depression at 6 months after CS (n=16) had significantly lower anandamide and 2-AG levels during the perioperative period. Conclusions: A low perioperative EC response may indicate an increased risk for early cognitive dysfunction and long-term depression in patients after CS. Glucocorticoids do not seem to influence this relationship.

New research on MS-related cognitive dysfunction from AAN 2011.