POPULARITY
As colorectal cancer rates rise among younger adults, surgeons are increasingly caring for patients with rectal cancer who are pregnant or hoping to preserve future fertility. With more individuals delaying childbearing, balancing effective cancer treatment with fertility preservation and maternal–fetal safety has become an important clinical challenge. This timely topic was recently highlighted by Dr. Sharon Suwanabol during a presentation at the American Society of Colon and Rectal Surgeons annual meeting 2026. In this episode, we explore the intersection of rectal cancer, fertility, and pregnancy through a multidisciplinary, case-based discussion. We review how surgery, chemotherapy, and pelvic radiation can affect fertility and sexual function in both men and women, and why early counseling and referral to reproductive endocrinology specialists are essential. The discussion also emphasizes that evaluation and treatment during pregnancy can often be performed safely, with care individualized based on tumor stage, gestational age, and the patient's goals and values. Hosts and discussants · Dr. Betelhem Yohannes, General surgery resident at the University of Washington · Dr. Griffen Allen, General surgery resident at the University of Washington · Dr. Raga Siddharthan, Assistant Professor of Surgery in the Section of Colorectal Surgery at the University of Washington · Dr. Stacey Cohen, Professor in the Division of Hematology and Oncology at the University of Washington and a gastrointestinal medical oncologist at Fred Hutch Cancer Center, specializing in colorectal and other GI cancers. Learning objectives · Describe the impact of rectal cancer surgery on fertility, sexual function, and future childbearing potential. · Review the effects of chemotherapy and pelvic radiation on reproductive health and fertility preservation. · Discuss available fertility preservation strategies and the importance of early pre-treatment counseling and referral. · Recognize the diagnostic challenges of rectal cancer during pregnancy, including overlapping gastrointestinal symptoms. · Review appropriate staging and workup considerations for suspected rectal cancer in pregnant patients. · Discuss multidisciplinary management strategies for rectal cancer during pregnancy, including individualized treatment sequencing. · Examine ethical and patient-centered considerations when balancing maternal cancer treatment and fetal outcomes. References Siegel RL, Wagle NS, Star J, Kratzer TB, Smith RA, Jemal A. Colorectal cancer statistics, 2026. CA Cancer J Clin. 2026;76(2):e70067. doi:10.3322/caac.70067 [https://pubmed.ncbi.nlm.nih.gov/38240409/] Pregnancy at Age 35 Years or Older: ACOG Obstetric Care Consensus No. 11. Obstet Gynecol. 2022;140(2):348-366. doi:10.1097/AOG.0000000000004873 [https://pubmed.ncbi.nlm.nih.gov/35640237/] Stal J, YI SY, Cohen-Cutler S, et al. Fertility Preservation Discussions Between Young Adult Rectal Cancer Survivors and Their Providers: Sex-Specific Prevalence and Correlates. Oncologist. 2022;27(7):579-586. doi:10.1093/oncolo/oyac052 [https://pubmed.ncbi.nlm.nih.gov/35708892/] Druvefors E, Myrelid P, Andersson RE, Landerholm K. Female and Male Fertility after Colectomy and Reconstructive Surgery in Inflammatory Bowel Disease: A National Cohort Study from Sweden. J Crohns Colitis. 2023;17(10):1631-1638. doi:10.1093/ecco-jcc/jjad079 [https://pubmed.ncbi.nlm.nih.gov/37341355/] Ito M, Tsukada Y, Watanabe J, et al. Long-term survival and functional outcomes of laparoscopic surgery for clinical stage I ultra-low rectal cancers located within 5 cm of the anal verge: A prospective phase II trial (Ultimate trial). Ann Surg. Published online April 1, 2024. doi:10.1097/SLA.0000000000006290 [https://pubmed.ncbi.nlm.nih.gov/38629555/] Teh WT, Stern C, Chander S, Hickey M. The impact of uterine radiation on subsequent fertility and pregnancy outcomes. Biomed Res Int. 2014;2014:482968. Johnson GGRJ, Park J, Helewa RM, Goldenberg BA, Nashed M, Hyun E. Total neoadjuvant therapy for rectal cancer: a guide for surgeons. Can J Surg. 2023 Apr 21;66(2):E196-E201. doi: 10.1503/cjs.005822. PMID: 37085291; PMCID: PMC10125160. [https://pubmed.ncbi.nlm.nih.gov/37085291/] Naren G, Guo J, Bai Q, Fan N, Nashun B. Reproductive and developmental toxicities of 5-fluorouracil in model organisms and humans. Expert Rev Mol Med. 2022 Jan 31;24:e9. doi: 10.1017/erm.2022.3. PMID: 35098910; PMCID: PMC9884763. [https://pubmed.ncbi.nlm.nih.gov/35098910/] National Comprehensive Cancer Network. (2026). NCCN Clinical Practice Guidelines in Oncology: Rectal Cancer (Version 2.2026). Retrieved from NCCN Guidelines for Rectal Cancer [https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1449] Oktay, Kutluk M.D., Ph.D.. Expert Commentary on Fertility Preservation in Colorectal Cancers: Current State and Practical Tips for the Cancer Practitioner. Diseases of the Colon & Rectum 63(6):p 726-727, June 2020. | DOI: 10.1097/DCR.0000000000001688 [https://pubmed.ncbi.nlm.nih.gov/32479532/] Stal J, YI SY, Cohen-Cutler S, et al. Fertility Preservation Discussions Between Young Adult Rectal Cancer Survivors and Their Providers: Sex-Specific Prevalence and Correlates. Oncologist. 2022;27(7):579-586. doi:10.1093/oncolo/oyac052 [https://pubmed.ncbi.nlm.nih.gov/35708892/] Gentile G, Ciccarone M. Management of fertility preservation in young female patients with gastrointestinal cancer: A case series and systematic literature review. Curr Probl Cancer. 2025;57:101221. doi:10.1016/j.currproblcancer.2025.101221 [https://pubmed.ncbi.nlm.nih.gov/39598263/] Saif MW. Management of colorectal cancer in pregnancy: a multimodality approach. Clin Colorectal Cancer. 2005;5(4):247-256. doi:10.3816/ccc.2005.n.035 [https://pubmed.ncbi.nlm.nih.gov/16183863/] Rogers JE, Dasari A, Eng C. The Treatment of Colorectal Cancer During Pregnancy: Cytotoxic Chemotherapy and Targeted Therapy Challenges. Oncologist. 2016 May;21(5):563-70. doi: 10.1634/theoncologist.2015-0362. Epub 2016 Mar 21. PMID: 27000464; PMCID: PMC4861360. [https://pubmed.ncbi.nlm.nih.gov/27000464/] Jiang Q, Hua H. Fertility in young-onset colorectal patients with cancer: a review. Oncologist. 2024;29(10):e1237-e1245. doi:10.1093/oncolo/oyae141 [https://pubmed.ncbi.nlm.nih.gov/39292850/] Dolmans MM, Hollanders de Ouderaen S, Demylle D, Pirard C. Utilization rates and results of long-term embryo cryopreservation before gonadotoxic treatment. J Assist Reprod Genet. 2015;32(8):1233-1237. doi:10.1007/s10815-015-0533-z [https://pubmed.ncbi.nlm.nih.gov/26162569/ Moawad NS, Santamaria E, Rhoton-Vlasak A, Lightsey JL. Laparoscopic Ovarian Transposition Before Pelvic Cancer Treatment: Ovarian Function and Fertility Preservation. J Minim Invasive Gynecol. 2017;24(1):28-35. doi:10.1016/j.jmig.2016.08.831 [https://pubmed.ncbi.nlm.nih.gov/27599763/] Fish R. Ovarian transposition in rectal cancer: uncertain benefit at a high price. Colorectal Dis. 2022;24(6):706-707. doi:10.1111/codi.16086 [https://pubmed.ncbi.nlm.nih.gov/35191146/] Ribeiro R, Baiocchi G, Moretti-Marques R, Linhares JC, Costa CN, Pareja R. Uterine transposition for fertility and ovarian function preservation after radiotherapy. Int J Gynecol Cancer. 2023;33(12):1837-1842. Published 2023 Dec 4. doi:10.1136/ijgc-2023-004723 [https://pubmed.ncbi.nlm.nih.gov/38104863/] Haggar F, Pereira G, Preen D, et al. Maternal and neonatal outcomes in pregnancies following colorectal cancer. Surg Endosc. 2013;27(7):2327-2336. doi:10.1007/s00464-012-2774-6 [https://pubmed.ncbi.nlm.nih.gov/23645367/] Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
In questo episodio, vedremo come il gioco spontaneo e il malessere dei bambini e delle bambine sono correlati, evidenziando la crescente crisi della salute mentale infantile e il legame con la diminuzione del tempo dedicato al gioco libero.Analizzeremo ricerche e studi significativi, inclusi quelli di esperti come Peter Gray e Stuart Brown, per comprendere l'importanza del gioco nella crescita e nella salute mentale. Unisciti a noi per scoprire come il gioco libero possa fare la differenza nel benessere dei più piccoli.PER APPROFONDIRELa piramide dello sviluppo https://www.spreaker.com/episode/la-piramide-dell-apprendimento--60988043 Il gioco autodirettohttps://www.spreaker.com/episode/gioco-e-protagonismo-dei-bambini--63435948Webinar gratuito con Peter Grayhttps://percorsiformativi06.it/prodotto/il-gioco-spontaneo-e-leducazione-auto-diretta-una-conversazione-con-peter-gray/http://www.scholarpedia.org/article/Consequences_of_Play_Deprivationhttp://www.scholarpedia.org/article/Definitions_of_Play https://files.eric.ed.gov/fulltext/EJ985541.pdf https://www.jpeds.com/article/S0022-3476(23)00111-7/abstracthttps://www.researchgate.net/publication/265196016_The_Special_Value_of_Children's_Age-Mixed_Play https://cdn2.psychologytoday.com/assets/attachments/1195/play-h-g-social-existence-ajp.pdfhttps://cms.learningthroughplay.com/media/esriqz2x/role-of-play-in-childrens-development-review_web.pdf https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2824286https://news.feinberg.northwestern.edu/2025/06/06/youth-anxiety-and-depression-increasing-study-finds/https://www.researchgate.net/publication/318922871_Correlates_of_children's_independent_outdoor_play_Crosssectional_analyses_from_the_Millennium_Cohort_Study#:~:text=Independent%20outdoor%20play%20was%20associated,Younger%20children%2C%20those%20from%20ahttps://www.sciencedirect.com/science/article/pii/S0885200621001411https://mylittlescholars.com.au/the-benefits-of-mixing-ages-together-in-early-learning/https://play.wales/wp-content/uploads/2024/03/Play-deprivation-2024v2.pdf https://nifplay.org/ https://publications.aap.org/pediatrics/article/142/3/e20182058/38649/The-Power-of-Play-A-Pediatric-Role-in-Enhancing?autologincheck=redirected PER CONTINUARE A SEGUIRE PF06SITO www.percorsiformativi06.itINSTAGRAM https://www.instagram.com/percorsiformativi06/YOUTUBE https://www.youtube.com/c/SilviaIaccarinoPercorsiformativi06/videosFB https://www.facebook.com/percorsiformativi06GRUPPO FB https://www.facebook.com/groups/177748889440303/TELEGRAM https://t.me/percorsiformativi06NEWSLETTER https://percorsiformativi06.it/iscrizione-alla-newsletter/RIEPILOGO DEI NOSTRI CONTENUTI https://linktr.ee/pf06DISCLAIMER I contenuti dei podcast sono forniti a solo scopo educativo e informativo. Questi non intendono in alcun modo sostituire consulenze, diagnosi o trattamenti forniti da professionisti del settore medico, psicologico o di altre discipline specialistiche.I contenuti proposti non costituiscono consigli professionali personalizzati né possono essere considerati esaustivi o adattabili a specifiche esigenze individuali. Nulla di quanto offerto qui è inteso per essere utilizzato come strumento diagnostico o terapeutico.Percorsi Formativi 0-6 e i suoi formatori non si assumono alcuna responsabilità per l'uso improprio delle informazioni contenute in questo podcast. Ogni utente è invitato a rivolgersi a professionisti qualificati per consulenze mirate riguardanti la propria salute fisica o mentale. In caso di dubbi su eventuali diagnosi o trattamenti per problemi di salute, raccomandiamo di consultare sempre un medico, uno psicologo o altro operatore sanitario qualificato.
Europe's NATO members have pledged 3.5% of GDP to rearmament. The political argument is already about which social programmes will be sacrificed to pay for this, when the government chooses guns instead of butter. What does history tell us about what politicians will do?Christoph Trebesch and Johannes Marzian spent four years assembling the Global Budget Database: 150 years of primary government budget documents from 20 countries, with 116 identified military spending booms in peace and war. They find that governments almost never cut social spending when they rearm; they expand both military and welfare budgets simultaneously. The bill arrives later, as higher taxes. Top income rates typically rise by 10 to 15 percentage points in the decade following a military boom, funded mainly through broad-based income and value-added taxes. With rearmament underway, will history repeat itself?The research behind this episode:Marzian, Johannes, and Christoph Trebesch. 2026. "Guns and Butter: The Fiscal Consequences of Rearmament and War." CEPR Discussion Paper 21193. [Gated]To cite this episode:Phillips, Tim, and Christoph Trebesch. 2026. "Guns and Butter." VoxTalks Economics (podcast). Assign this as extra listening. The citation above is formatted and ready for a reading list or VLE.About the guestChristoph Trebesch is Director of the Research Center on International Finance at the Kiel Institute for the World Economy and Professor of Macroeconomics at Kiel University. His research spans sovereign debt, financial crises, China's role in global finance, the economics of populism, and the long-run fiscal history of military spending. He is a Research Fellow of the Centre for Economic Policy Research (CEPR). In 2024 he received the Hermann Heinrich Gossen Award, Germany's leading economics prize for economists under 45.Research cited in this episodeThe Global Budget Database is the primary dataset introduced in this paper. Marzian and Trebesch constructed it from primary archival sources, including national parliamentary budget documents, for 20 countries from 1870 to 2022. Unlike existing datasets that rely on planned rather than realised expenditures, it records what governments actually spent, broken down by ministry and purpose. The Switzerland case illustrates the stakes: standard sources record Swiss military spending at around 2% of GDP during the World Wars. The archival record shows actual spending reached 10% once off-budget items are included; five times the apparent figure.The Correlates of War (COW) Military Expenditures Dataset is one of the most widely used secondary-source datasets for historical military spending, maintained by the Correlates of War Project. Trebesch uses the Swiss case to illustrate the limitations of secondary-source data: the COW series misses off-budget military items that primary archival documents capture, producing a significantly distorted picture of wartime mobilisation in a number of countries.Credit booms methodology provided the template for identifying military spending booms. Trebesch and Marzian define a boom as an increase of at least 6.5 percentage points of military spending as a share of GDP over two consecutive years, ending when spending growth falls to zero. This approach, adapted from the literature on financial credit expansions and their economic consequences, allows systematic cross-country and cross-period identification without relying on retrospective classification alone. Each algorithmically flagged episode was then verified against historical sources.Local projections are the main statistical technique used to trace the long-run fiscal path following military booms. The method estimates how a variable (here, tax revenues and top income rates) evolves over time following an identified shock. It is well suited to the protracted dynamics Trebesch and Marzian observe: tax rates rising over a decade or more after a military buildup and, critically, not returning to pre-boom levels once the spending episode ends.Exogenous military shocks are the basis of the paper's causal identification strategy. To separate the fiscal effects of military spending from broader economic conditions, the authors distinguish episodes triggered by external geopolitical events from those driven by domestic factors. France's rearmament in the mid-1930s, forced by Nazi Germany's military expansion regardless of French domestic politics, is used as an example of an exogenous peacetime boom. Germany's own rearmament in the same period would not qualify as exogenous, since Germany initiated the shock. The same logic applies to wars: a country attacked faces an exogenous event; the attacker does not.More VoxTalks Economics episodesIn Can Europe Defend Itself?, featuring Moritz Schularick, Christoph's colleague from the Kiel Institute, we examine whether Europe has the industrial and strategic capacity to convert its rearmament commitment into credible deterrence, and what European rearmament could mean in practice. Related reading on VoxEUDefence spending: no free lunch, a VoxEU column arguing that increased military expenditure adds modestly to near-term economic activity while adding to fiscal pressure; lasting economic benefits from rearmament are far from guaranteed.Macroeconomic impacts of defence spending, a VoxEU column modelling the EU-wide effects of raising NATO members' defence spending to 5% of GDP by 2035; projected GDP gains are modest and come at the cost of higher debt-to-GDP ratios.Converging military spending and its fiscal consequences, a VoxEU column examining long-run trends in military expenditure across countries and the fiscal footprint they leave behind.The economic effects of military support for Ukraine: evidence from fiscal multipliers in donor countries, a VoxEU column finding that spending multipliers for military expenditure can exceed those for other categories of public spending.
Video: https://www.youtube.com/watch?v=hTW8CSPVEGcIn this whiteboard episode, we revisit the basal ganglia's intricate circuitry, detailing its five subcortical nuclei—dorsal striatum (caudate/putamen inputs), globus pallidus externa/subthalamic relays, and globus pallidus interna/substantia nigra reticulata outputs—driving the classic direct (facilitatory "go") and indirect (suppressive "no-go") pathways for action selection and inhibition. Excitatory cortical inputs converge on medium spiny neurons, finely tuned by dopamine (D1 excitatory/D2 inhibitory via substantia nigra pars compacta), serotonin, and acetylcholine, to orchestrate habits, motivation, and movement suppression through thalamic modulation. In autism, morphological alterations in medium spiny neurons—enlarged dendritic spines and reduced synaptic flexibility—bias toward repetitive behaviors, ritualized patterns, and intensely fixated interests (DSM-5 B2/B3 criteria), underscoring the circuit's preference for sameness via strengthened plasticity and limited prefrontal override.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Basal Ganglia Intro Review prior episodes on basal ganglia (48-50 + 47); key for movements, habits, motivation, repetition in autism00:55 Five Subcortical Areas Dorsal striatum (caudate/putamen = inputs); relays (globus pallidus external, subthalamic nucleus); outputs (globus pallidus internal, substantia nigra reticulata)02:54 Direct Pathway (Go) Excitatory cortex → dorsal striatum → inhibits internal pallidus/reticulata → frees thalamus → activates movement06:34 Indirect Pathway (No-Go) Cortex → dorsal striatum → external pallidus → subthalamic → excites outputs → inhibits thalamus → suppresses movement11:25 Major Inputs Cortex (esp. sensory-motor/prefrontal); thalamus (alerts); substantia nigra compacta (dopamine D1/D2 modulation)13:32 Modulators & Cortex Regions Serotonin (patience); acetylcholine (focus shift); inputs from sensory-motor (habits), prefrontal (planning), parietal (context)18:42 Medium Spiny Neurons Dorsal striatum cells with larger spines; repetitive firing strengthens synapses (morphology/plasticity)23:20 Autistic Differences Larger dendrites/spines → limited flexibility; favors sameness/habits; reduced prefrontal influence28:42 DSM Criteria B2/B3 Link B2: repetitive behaviors/rituals; B3: restricted/fixated interests—core autistic traits tied to basal ganglia habits/intensity32:24 Motivation & Change Basal ganglia (not individual) defines motivation via strengthened connections; explains difficulty with change, splinter skillsX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com
A pedofilia tem sido considerada, pelos discursos sociais, como a ‘mais abjeta' entre as perversões. No discurso médico, é uma patologia e refere-se ao fato de um adulto tomar crianças como objeto sexual. Será a pedofilia um pecado, um crime, uma doença? E como lidar com ela? Esta é a segunda de duas partes.Confira o papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.>> OUÇA (44min 42s)*PARTICIPAÇÕES ESPECIAISSvetlanna, ou Lanna, é trabalhadora sexual há 8 anos, voluntária no NEP (Núcleo de Estudos da Рrostituição em Porto Alegre), "putativista". No Twitter: @sv3tlannaJuliana Molina Constantino, psicóloga clínica, forense, escritora e educadora. Na clínica trabalha com adultos vítimas de abuso sexual infantil; na justiça atua conduzindo Depoimentos Especiais e realizando Perícias Psicológicas de crianças e adolescentes em processos de apuração de violência de todos os tipos, mas, principalmente a sexual. No Instagram: @psijuconstantino* Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br*REFERÊNCIASPedofilia: revisão médica e repercussões penais https://www.teses.usp.br/teses/disponiveis/2/2136/tde-10042024-121635/en.phpOs árbitros do desejo e os enteados da natureza: controvérsias e ontologias sobre a categoria pedofilia em torno do DSM - 5 https://www.bdtd.uerj.br:8443/handle/1/19240Aspectos Psicológicos dos Protagonistas de Incestohttps://bdtd.ucb.br:8443/jspui/bitstream/123456789/1884/1/Texto%20Completo.pdfParafilias: uma classificação fenomenológicahttps://actaspsiquiatria.es/index.php/actas/article/download/564/821A Review of Academic Use of the Term “Minor Attracted Persons”https://journals.sagepub.com/doi/10.1177/15248380241270028Sexual interest in children among an online sample of men and women: prevalence and correlateshttps://pubmed.ncbi.nlm.nih.gov/24215791/Correlates and moderators of child pornography consumption in a community samplehttps://pubmed.ncbi.nlm.nih.gov/24088812/PSIQUIATRIA E PEDOFILIA: A ORGANIZAÇÃO B4U-ACT E O DIREITO À SAÚDE MENTAL DAS PESSOAS ATRAÍDAS POR MENORES (MAPS)https://proceedings.science/abrascao-2022/trabalhos/psiquiatria-e-pedofilia-a-organizacao-b4u-act-e-o-direito-a-saude-mental-das-pesThe DSM and the Stigmatization of People who Are Attracted to Minorshttps://www.researchgate.net/profile/Richard-Kramer-10/publication/365993590_The_DSM_and_the_Stigmatization_of_People_who_Are_Attracted_to_Minors/links/638bd5d7ca2e4b239c8896e1/The-DSM-and-the-Stigmatization-of-People-who-Are-Attracted-to-Minors.pdfChanging public attitudes toward minor attracted persons: an evaluation of an anti-stigma intervention https://www.tandfonline.com/doi/abs/10.1080/13552600.2020.1863486?casa_token=iK-wFTzYUbYAAAAA:UmI5w_4dc4d4C9FU9Z1OCpTp5oVb1CkeC1ygV8rg94GSUCUVG886jSpFi6sD_c8uDJQm4gQudZBIQualitative Analysis of Minor Attracted Persons' Subjective Experience: Implications for Treatment https://www.tandfonline.com/doi/abs/10.1080/0092623X.2022.2126808?casa_token=uNwM4nBfx9UAAAAA:Jo75nZFTKEtnYsLlbO2k0hBMaSc5iUC2a2hrGyWF_C5kRNI-ghibqhF01eZPhAv8ygWg-OHWAPyfBeing Sexually Attracted to Minors: Sexual Development, Coping With Forbidden Feelings, and Relieving Sexual Arousal in Self-Identified Pedophiles https://www.tandfonline.com/doi/full/10.1080/0092623X.2015.1061077?src=recsysA Long, Dark Shadow: Minor-Attracted People and Their Pursuit of Dignityhttps://books.google.com.br/books?hl=en&lr=&id=SksqEAAAQBAJ&oi=fnd&pg=PP9&dq=(MAPS)+attracted+by+minors&ots=h0RKV2g6vr&sig=39-uleVMpIgO4bkjPKShVScmfh0&redir_esc=y#v=onepage&q=(MAPS)%20attracted%20by%20minors&f=falseMisrepresenting the “MAP” Literature Does Little to Advance Child Abuse Prevention: A Critical Commentary and Response to Farmer, Salter, and Woodlockhttps://journals.sagepub.com/doi/full/10.1177/15248380251332197Outpatient Therapists' Perspectives on Working With Persons Who Are Sexually Interested in Minorshttps://link.springer.com/article/10.1007/s10508-022-02377-6The Terminology of “Minor Attracted People” and the Campaign to De-stigmatize Paedophilia Originated in Pro-pedophile Advocacyhttps://journals.sagepub.com/doi/full/10.1177/15248380251332198A Profile of Pedophilia: Definition, Characteristics of Offenders, Recidivism, Treatment Outcomes, and Forensic Issueshttps://www.mayoclinicproceedings.org/article/S0025-6196(11)61074-4/abstracthttps://linkinghub.elsevier.com/retrieve/pii/S0025619611610744Pedophilia and Sexual Offending Against Childrenhttps://www.apa.org/pubs/books/4317491Intervention Needs in Prison With Pedophile Inmateshttps://www.papelesdelpsicologo.es/pii?pii=3027Child molester or paedophile? Sociolegal versus psychopathological classification of sexual offenders against children https://www.tandfonline.com/doi/full/10.1080/13552600802133860School sex education, a process for evaluation: methodology and results https://academic.oup.com/her/article-abstract/11/2/205/628476Teachers' Attitudes and Opinions Toward Sexuality Education in School: A Systematic Review of Secondary and High School Teachers https://www.tandfonline.com/doi/abs/10.1080/15546128.2024.2353708‘Chronophilia': Entries of Erotic Age Preference into Descriptive Psychopathologyhttps://www.cambridge.org/core/journals/medical-history/article/chronophilia-entries-of-erotic-age-preference-into-descriptive-psychopathology/1896C08F07CB5F1A428CEEF3E1104586Biological Factors in the Development of Sexual Deviance and Aggression in Males.https://psycnet.apa.org/record/2006-12464-004Mamilos 123 - Pedofilia (2017)https://open.spotify.com/episode/3RxgeS0ZovQue7lK61TLkiNaruhodo #403 - Por que temos fetiches sexuais?https://www.youtube.com/watch?v=C-ET1nIP6WMNaruhodo #433 - Existe amizade entre homens e mulheres? - Parte 1 de 2https://www.youtube.com/watch?v=EFVaBfGaowgNaruhodo #434 - Existe amizade entre homens e mulheres? - Parte 2 de 2https://www.youtube.com/watch?v=H6D1yCni0rcNaruhodo #437 - O termo "macho alfa" faz sentido? - Parte 1 de 2https://www.youtube.com/watch?v=Qx1z1R_He_cNaruhodo #438 - O termo "macho alfa" faz sentido? - Parte 2 de 2https://www.youtube.com/watch?v=UNKh0Zd3h_kNaruhodo #399 - Assistir à pornografia vicia?https://www.youtube.com/watch?v=vByA0QVSOb8Naruhodo #150 - O que é o "No Fap September"?https://www.youtube.com/watch?v=8yWTngyTq1gNaruhodo #325 - Por que nos apaixonamos por vilões? - Parte 1 de 2https://www.youtube.com/watch?v=o9F4Q_jjF88Naruhodo #326 - Por que nos apaixonamos por vilões? - Parte 2 de 2https://www.youtube.com/watch?v=4gtkstkqpUwNaruhodo #320 - Por que nos identificamos com vilões?https://www.youtube.com/watch?v=ZH5aTG0xeLwNaruhodo #419 - Maconha faz mal? - Parte 1 de 2https://www.youtube.com/watch?v=cvLTh2bKPiQNaruhodo #420 - Maconha faz mal? - Parte 2 de 2https://www.youtube.com/watch?v=F7wVcGvpoGA*APOIE O NARUHODO!O Altay e eu temos duas mensagens pra você.A primeira é: muito, muito obrigado pela sua audiência. Sem ela, o Naruhodo sequer teria sentido de existir. Você nos ajuda demais não só quando ouve, mas também quando espalha episódios para familiares, amigos - e, por que não?, inimigos.A segunda mensagem é: existe uma outra forma de apoiar o Naruhodo, a ciência e o pensamento científico - apoiando financeiramente o nosso projeto de podcast semanal independente, que só descansa no recesso do fim de ano.Manter o Naruhodo tem custos e despesas: servidores, domínio, pesquisa, produção, edição, atendimento, tempo... Enfim, muitas coisas para cobrir - e, algumas delas, em dólar.A gente sabe que nem todo mundo pode apoiar financeiramente. E tá tudo bem. Tente mandar um episódio para alguém que você conhece e acha que vai gostar.A gente sabe que alguns podem, mas não mensalmente. E tá tudo bem também. Você pode apoiar quando puder e cancelar quando quiser. O apoio mínimo é de 15 reais e pode ser feito pela plataforma ORELO ou pela plataforma APOIA-SE. Para quem está fora do Brasil, temos até a plataforma PATREON.É isso, gente. Estamos enfrentando um momento importante e você pode ajudar a combater o negacionismo e manter a chama da ciência acesa. Então, fica aqui o nosso convite: apóie o Naruhodo como puder.bit.ly/naruhodo-no-orelo
A pedofilia tem sido considerada, pelos discursos sociais, como a ‘mais abjeta' entre as perversões. No discurso médico, é uma patologia e refere-se ao fato de um adulto tomar crianças como objeto sexual. Será a pedofilia um pecado, um crime, uma doença? E como lidar com ela? Esta é a primeira de duas partes.Confira o papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.>> OUÇA (52min 52s)* PARTICIPAÇÕES ESPECIAISSvetlanna, ou Lanna, é trabalhadora sexual há 8 anos, voluntária no NEP (Núcleo de Estudos da Рrostituição em Porto Alegre), "putativista". No Twitter: @sv3tlannaJuliana Molina Constantino, psicóloga clínica, forense, escritora e educadora. Na clínica trabalha com adultos vítimas de abuso sexual infantil; na justiça atua conduzindo Depoimentos Especiais e realizando Perícias Psicológicas de crianças e adolescentes em processos de apuração de violência de todos os tipos, mas, principalmente a sexual. No Instagram: @psijuconstantino*Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br*APOIO: INSIDERIlustríssima ouvinte, ilustríssimo ouvinte do Naruhodo, Seguimos firmes e fortes na Black November INSIDER, a maior promoção da história da marca e o mês mais feliz para quem gosta de se vestir de maneira inteligente! Você já deve ter percebido como as condições do tempo andam malucas: amanhece frio, depois esquenta, depois esfria de novo, quando não chove entre uma coisa e outra...Sabe qual a solução ideal para dias assim? A Tech Long Sleeve Masculina, a camiseta tecnológica INSIDER com mangas longas.Você tem regulação térmica e toque leve, sem passar calor nem passar frio: é garantia de performance em qualquer estação.Na Black November INSIDER, elas podem sair com até 50% de desconto, combinando o cupom NARUHODO com os descontos do site.E você pode aproveitar ainda mais a promoção: entrando no canal de WhatsApp da INSIDER, onde acontecem as FLASH PROMOS, com descontos ainda maiores, por tempo super limitado.Então não deixe pra depois e entre agora mesmo no grupo de Zap no link:https://creators.insiderstore.com.br/NARUHODOWPPBFOu clique no link que está na descrição deste episódio.INSIDER: inteligência em cada escolha.#InsiderStore*REFERÊNCIASPedofilia: revisão médica e repercussões penais https://www.teses.usp.br/teses/disponiveis/2/2136/tde-10042024-121635/en.phpOs árbitros do desejo e os enteados da natureza: controvérsias e ontologias sobre a categoria pedofilia em torno do DSM - 5 https://www.bdtd.uerj.br:8443/handle/1/19240Aspectos Psicológicos dos Protagonistas de Incestohttps://bdtd.ucb.br:8443/jspui/bitstream/123456789/1884/1/Texto%20Completo.pdfParafilias: uma classificação fenomenológicahttps://actaspsiquiatria.es/index.php/actas/article/download/564/821A Review of Academic Use of the Term “Minor Attracted Persons”https://journals.sagepub.com/doi/10.1177/15248380241270028Sexual interest in children among an online sample of men and women: prevalence and correlateshttps://pubmed.ncbi.nlm.nih.gov/24215791/Correlates and moderators of child pornography consumption in a community samplehttps://pubmed.ncbi.nlm.nih.gov/24088812/PSIQUIATRIA E PEDOFILIA: A ORGANIZAÇÃO B4U-ACT E O DIREITO À SAÚDE MENTAL DAS PESSOAS ATRAÍDAS POR MENORES (MAPS)https://proceedings.science/abrascao-2022/trabalhos/psiquiatria-e-pedofilia-a-organizacao-b4u-act-e-o-direito-a-saude-mental-das-pesThe DSM and the Stigmatization of People who Are Attracted to Minorshttps://www.researchgate.net/profile/Richard-Kramer-10/publication/365993590_The_DSM_and_the_Stigmatization_of_People_who_Are_Attracted_to_Minors/links/638bd5d7ca2e4b239c8896e1/The-DSM-and-the-Stigmatization-of-People-who-Are-Attracted-to-Minors.pdfChanging public attitudes toward minor attracted persons: an evaluation of an anti-stigma intervention https://www.tandfonline.com/doi/abs/10.1080/13552600.2020.1863486?casa_token=iK-wFTzYUbYAAAAA:UmI5w_4dc4d4C9FU9Z1OCpTp5oVb1CkeC1ygV8rg94GSUCUVG886jSpFi6sD_c8uDJQm4gQudZBIQualitative Analysis of Minor Attracted Persons' Subjective Experience: Implications for Treatment https://www.tandfonline.com/doi/abs/10.1080/0092623X.2022.2126808?casa_token=uNwM4nBfx9UAAAAA:Jo75nZFTKEtnYsLlbO2k0hBMaSc5iUC2a2hrGyWF_C5kRNI-ghibqhF01eZPhAv8ygWg-OHWAPyfBeing Sexually Attracted to Minors: Sexual Development, Coping With Forbidden Feelings, and Relieving Sexual Arousal in Self-Identified Pedophiles https://www.tandfonline.com/doi/full/10.1080/0092623X.2015.1061077?src=recsysA Long, Dark Shadow: Minor-Attracted People and Their Pursuit of Dignityhttps://books.google.com.br/books?hl=en&lr=&id=SksqEAAAQBAJ&oi=fnd&pg=PP9&dq=(MAPS)+attracted+by+minors&ots=h0RKV2g6vr&sig=39-uleVMpIgO4bkjPKShVScmfh0&redir_esc=y#v=onepage&q=(MAPS)%20attracted%20by%20minors&f=falseMisrepresenting the “MAP” Literature Does Little to Advance Child Abuse Prevention: A Critical Commentary and Response to Farmer, Salter, and Woodlockhttps://journals.sagepub.com/doi/full/10.1177/15248380251332197Outpatient Therapists' Perspectives on Working With Persons Who Are Sexually Interested in Minorshttps://link.springer.com/article/10.1007/s10508-022-02377-6The Terminology of “Minor Attracted People” and the Campaign to De-stigmatize Paedophilia Originated in Pro-pedophile Advocacyhttps://journals.sagepub.com/doi/full/10.1177/15248380251332198A Profile of Pedophilia: Definition, Characteristics of Offenders, Recidivism, Treatment Outcomes, and Forensic Issueshttps://www.mayoclinicproceedings.org/article/S0025-6196(11)61074-4/abstracthttps://linkinghub.elsevier.com/retrieve/pii/S0025619611610744Pedophilia and Sexual Offending Against Childrenhttps://www.apa.org/pubs/books/4317491Intervention Needs in Prison With Pedophile Inmateshttps://www.papelesdelpsicologo.es/pii?pii=3027Child molester or paedophile? Sociolegal versus psychopathological classification of sexual offenders against children https://www.tandfonline.com/doi/full/10.1080/13552600802133860School sex education, a process for evaluation: methodology and results https://academic.oup.com/her/article-abstract/11/2/205/628476Teachers' Attitudes and Opinions Toward Sexuality Education in School: A Systematic Review of Secondary and High School Teachers https://www.tandfonline.com/doi/abs/10.1080/15546128.2024.2353708‘Chronophilia': Entries of Erotic Age Preference into Descriptive Psychopathologyhttps://www.cambridge.org/core/journals/medical-history/article/chronophilia-entries-of-erotic-age-preference-into-descriptive-psychopathology/1896C08F07CB5F1A428CEEF3E1104586Biological Factors in the Development of Sexual Deviance and Aggression in Males.https://psycnet.apa.org/record/2006-12464-004Mamilos 123 - Pedofilia (2017)https://open.spotify.com/episode/3RxgeS0ZovQue7lK61TLkiNaruhodo #403 - Por que temos fetiches sexuais?https://www.youtube.com/watch?v=C-ET1nIP6WMNaruhodo #433 - Existe amizade entre homens e mulheres? - Parte 1 de 2https://www.youtube.com/watch?v=EFVaBfGaowgNaruhodo #434 - Existe amizade entre homens e mulheres? - Parte 2 de 2https://www.youtube.com/watch?v=H6D1yCni0rcNaruhodo #437 - O termo "macho alfa" faz sentido? - Parte 1 de 2https://www.youtube.com/watch?v=Qx1z1R_He_cNaruhodo #438 - O termo "macho alfa" faz sentido? - Parte 2 de 2https://www.youtube.com/watch?v=UNKh0Zd3h_kNaruhodo #399 - Assistir à pornografia vicia?https://www.youtube.com/watch?v=vByA0QVSOb8Naruhodo #150 - O que é o "No Fap September"?https://www.youtube.com/watch?v=8yWTngyTq1gNaruhodo #325 - Por que nos apaixonamos por vilões? - Parte 1 de 2https://www.youtube.com/watch?v=o9F4Q_jjF88Naruhodo #326 - Por que nos apaixonamos por vilões? - Parte 2 de 2https://www.youtube.com/watch?v=4gtkstkqpUwNaruhodo #320 - Por que nos identificamos com vilões?https://www.youtube.com/watch?v=ZH5aTG0xeLwNaruhodo #419 - Maconha faz mal? - Parte 1 de 2https://www.youtube.com/watch?v=cvLTh2bKPiQNaruhodo #420 - Maconha faz mal? - Parte 2 de 2https://www.youtube.com/watch?v=F7wVcGvpoGA*APOIE O NARUHODO!O Altay e eu temos duas mensagens pra você.A primeira é: muito, muito obrigado pela sua audiência. Sem ela, o Naruhodo sequer teria sentido de existir. Você nos ajuda demais não só quando ouve, mas também quando espalha episódios para familiares, amigos - e, por que não?, inimigos.A segunda mensagem é: existe uma outra forma de apoiar o Naruhodo, a ciência e o pensamento científico - apoiando financeiramente o nosso projeto de podcast semanal independente, que só descansa no recesso do fim de ano.Manter o Naruhodo tem custos e despesas: servidores, domínio, pesquisa, produção, edição, atendimento, tempo... Enfim, muitas coisas para cobrir - e, algumas delas, em dólar.A gente sabe que nem todo mundo pode apoiar financeiramente. E tá tudo bem. Tente mandar um episódio para alguém que você conhece e acha que vai gostar.A gente sabe que alguns podem, mas não mensalmente. E tá tudo bem também. Você pode apoiar quando puder e cancelar quando quiser. O apoio mínimo é de 15 reais e pode ser feito pela plataforma ORELO ou pela plataforma APOIA-SE. Para quem está fora do Brasil, temos até a plataforma PATREON.É isso, gente. Estamos enfrentando um momento importante e você pode ajudar a combater o negacionismo e manter a chama da ciência acesa. Então, fica aqui o nosso convite: apóie o Naruhodo como puder.bit.ly/naruhodo-no-orelo
Worry seems like something most people do from time to time, but for some people, severe worry can become an overwhelming sensation, and for older adults later in life, severe worry has been associated with an increased risk of stroke and coronary heart disease. Carmen Andreescu is a professor of psychiatry and bioengineering at the University of Pittsburgh School of Medicine. She says mild worry is useful evolutionarily, to help us make plans or adapt behavior.Read the full study here: https://www.nature.com/articles/s41386-025-02193-1 Hosted on Acast. See acast.com/privacy for more information.
Stanislas DehaeneChaire Psychologie cognitive expérimentaleAnnée 2025-2026Collège de FranceColloque : Seeing the Mind, Educating the BrainTheme: Neural Codes in Monkeys and HumansSingle-Neuron Correlates of Perception and Memory in the Human Medial Temporal LobeColloque - Florian Mormann : Single-Neuron Correlates of Perception and Memory in the Human Medial Temporal LobeFlorian Mormann
Host: Jennifer Caudle, DO Guest: Katie Beadon, MD, MASc, FRCPC Multifocal motor neuropathy (MMN) is a chronic, immune-mediated motor neuropathy that can mimic other neuromuscular disorders1-3 and is one of the few motor neuron disorders that is treatable.4 However, disease severity correlates with the length of time a patient remains untreated, which is why early recognition and treatment initiation is essential for preserving long-term motor function.5-6 Joining Dr. Jennifer Caudle to discuss the diagnosis and management of MMN is Dr. Katie Beadon, Co-Director of St. Paul's Hospital Immunotherapy in Neurology Clinic and an Assistant Clinical Professor at the University of British Columbia in Vancouver. References: Guimarães-Costa R, Bombelli F, Léger JM. Multifocal motor neuropathy. Presse Med. 2013;42(6 Pt 2):e217-24. doi:10.1016/j.lpm.2013.01.057 Beadon K, Guimarães-Costa R, Léger JM. Multifocal motor neuropathy. Curr Opin Neurol. 2018;31(5):559-564. doi:10.1097/WCO.0000000000000605 Vlam L, van der Pol WL, Cats EA, et al. Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies. Nat Rev Neurol. 2011;8(1):48-58. doi:10.1038/nrneurol.2011.175 Yeh WZ, Dyck PJ, van den Berg LH, Kiernan MC, Taylor BV. Multifocal motor neuropathy: controversies and priorities. J Neurol Neurosurg Psychiatry. 2020;91(2):140-148. doi:10.1136/jnnp-2019-321532 Cats EA, van der Pol WL, Piepers S, et al. Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy. Neurology. 2010;75(9):818-25. doi:10.1212/WNL.0b013e3181f0738e Van …
Host: Jennifer Caudle, DO Guest: Katie Beadon, MD, MASc, FRCPC Multifocal motor neuropathy (MMN) is a chronic, immune-mediated motor neuropathy that can mimic other neuromuscular disorders1-3 and is one of the few motor neuron disorders that is treatable.4 However, disease severity correlates with the length of time a patient remains untreated, which is why early recognition and treatment initiation is essential for preserving long-term motor function.5-6 Joining Dr. Jennifer Caudle to discuss the diagnosis and management of MMN is Dr. Katie Beadon, Co-Director of St. Paul's Hospital Immunotherapy in Neurology Clinic and an Assistant Clinical Professor at the University of British Columbia in Vancouver. References: Guimarães-Costa R, Bombelli F, Léger JM. Multifocal motor neuropathy. Presse Med. 2013;42(6 Pt 2):e217-24. doi:10.1016/j.lpm.2013.01.057 Beadon K, Guimarães-Costa R, Léger JM. Multifocal motor neuropathy. Curr Opin Neurol. 2018;31(5):559-564. doi:10.1097/WCO.0000000000000605 Vlam L, van der Pol WL, Cats EA, et al. Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies. Nat Rev Neurol. 2011;8(1):48-58. doi:10.1038/nrneurol.2011.175 Yeh WZ, Dyck PJ, van den Berg LH, Kiernan MC, Taylor BV. Multifocal motor neuropathy: controversies and priorities. J Neurol Neurosurg Psychiatry. 2020;91(2):140-148. doi:10.1136/jnnp-2019-321532 Cats EA, van der Pol WL, Piepers S, et al. Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy. Neurology. 2010;75(9):818-25. doi:10.1212/WNL.0b013e3181f0738e Van …
Host: Jennifer Caudle, DO Guest: Katie Beadon, MD, MASc, FRCPC Multifocal motor neuropathy (MMN) is a chronic, immune-mediated motor neuropathy that can mimic other neuromuscular disorders1-3 and is one of the few motor neuron disorders that is treatable.4 However, disease severity correlates with the length of time a patient remains untreated, which is why early recognition and treatment initiation is essential for preserving long-term motor function.5-6 Joining Dr. Jennifer Caudle to discuss the diagnosis and management of MMN is Dr. Katie Beadon, Co-Director of St. Paul's Hospital Immunotherapy in Neurology Clinic and an Assistant Clinical Professor at the University of British Columbia in Vancouver. References: Guimarães-Costa R, Bombelli F, Léger JM. Multifocal motor neuropathy. Presse Med. 2013;42(6 Pt 2):e217-24. doi:10.1016/j.lpm.2013.01.057 Beadon K, Guimarães-Costa R, Léger JM. Multifocal motor neuropathy. Curr Opin Neurol. 2018;31(5):559-564. doi:10.1097/WCO.0000000000000605 Vlam L, van der Pol WL, Cats EA, et al. Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies. Nat Rev Neurol. 2011;8(1):48-58. doi:10.1038/nrneurol.2011.175 Yeh WZ, Dyck PJ, van den Berg LH, Kiernan MC, Taylor BV. Multifocal motor neuropathy: controversies and priorities. J Neurol Neurosurg Psychiatry. 2020;91(2):140-148. doi:10.1136/jnnp-2019-321532 Cats EA, van der Pol WL, Piepers S, et al. Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy. Neurology. 2010;75(9):818-25. doi:10.1212/WNL.0b013e3181f0738e Van …
Host: Jennifer Caudle, DO Guest: Katie Beadon, MD, MASc, FRCPC Multifocal motor neuropathy (MMN) is a chronic, immune-mediated motor neuropathy that can mimic other neuromuscular disorders1-3 and is one of the few motor neuron disorders that is treatable.4 However, disease severity correlates with the length of time a patient remains untreated, which is why early recognition and treatment initiation is essential for preserving long-term motor function.5-6 Joining Dr. Jennifer Caudle to discuss the diagnosis and management of MMN is Dr. Katie Beadon, Co-Director of St. Paul's Hospital Immunotherapy in Neurology Clinic and an Assistant Clinical Professor at the University of British Columbia in Vancouver. References: Guimarães-Costa R, Bombelli F, Léger JM. Multifocal motor neuropathy. Presse Med. 2013;42(6 Pt 2):e217-24. doi:10.1016/j.lpm.2013.01.057 Beadon K, Guimarães-Costa R, Léger JM. Multifocal motor neuropathy. Curr Opin Neurol. 2018;31(5):559-564. doi:10.1097/WCO.0000000000000605 Vlam L, van der Pol WL, Cats EA, et al. Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies. Nat Rev Neurol. 2011;8(1):48-58. doi:10.1038/nrneurol.2011.175 Yeh WZ, Dyck PJ, van den Berg LH, Kiernan MC, Taylor BV. Multifocal motor neuropathy: controversies and priorities. J Neurol Neurosurg Psychiatry. 2020;91(2):140-148. doi:10.1136/jnnp-2019-321532 Cats EA, van der Pol WL, Piepers S, et al. Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy. Neurology. 2010;75(9):818-25. doi:10.1212/WNL.0b013e3181f0738e Van …
Fire Chief Jeremy Bass of Abbeville County Fire Rescue (SC) brings over 30 years of fire service experience—spanning Charleston, Louisville, and rural South Carolina—into a conversation packed with lessons on leadership, resilience, and relationships. In this episode, Chief Bass shares why recruiting and retaining volunteers is less about numbers and more about building meaningful relationships, why fear is a liar and belief always comes before ability, and how losing six friends in the tragic Charleston Sofa Super Store fire forever changed his approach to training and mentorship. From coaching football to founding the Kentucky Brotherhood Ride, Chief Bass proves that leadership is about investing in people, honoring the past, and inspiring the future.
Send us a textDownload Upside and use my code MELINDA35278 to get 15¢ per gallon extra cash back on your first gas fill-up and 10% extra cash on your first food purchase! Download Fetch app using this link, submit a receipt and we'll both score bonus points. Calling All Educators! I started a community with resources, courses, articles, networking, and more. I am looking for members to help me build it with the most valuable resources. I would really appreciate your input as a teacher, leader, administrator, or consultant. Join here: Empowered Educator Community Book: Educator to Entrepreneur: IGNITE Your Path to Freelance SuccessGrab a complimentary POWER SessionWith Rubi.ai, you'll experience cutting-edge technology, research-driven insights, and efficient content delivery.email: melinda@empowere...
Send us a textThis episode is the first in a two-part series, a workshop-style discussion on organizing schools for success. My guests, Erica Glenn and Kim Bradley draw from the research of Larry Lezotte, focusing on his work on the seven correlates of effective schools. Seven Correlates of Effective Schools Strong Instructional Leadership: Emphasize the importance of effective leadership styles that empower and support staff. Clear & Focused Mission: Ensure the school's vision and values are well-defined, understood, and aligned with community expectations. Safe & Orderly Environment: Create a positive, welcoming, and secure school climate. Climate of High Expectations: Encourage a culture that fosters ambition, inclusivity, and achievable goals for all students. Frequent Monitoring of Student Progress: Highlight the significance of regular assessments and feedback to support student growth. Opportunity to Learn & Time on Task: Maximize learning time, minimize disruptions, and provide varied learning experiences. Home-School Relations: Stress the vital role of family and community engagement in school success. Youtube VideoWorkbookSummer ChecklistWebsitewww.linkedin.com/in/erica-glenn-76116b126 Download Upside and use my code MELINDA35278 to get 15¢ per gallon extra cash back on your first gas fill-up and 10% extra cash on your first food purchase! Download Fetch app using this link, submit a receipt and we'll both score bonus points. Calling All Educators! I started a community with resources, courses, articles, networking, and more. I am looking for members to help me build it with the most valuable resources. I would really appreciate your input as a teacher, leader, administrator, or consultant. Join here: Empowered Educator Community Book: Educator to Entrepreneur: IGNITE Your Path to Freelance SuccessGrab a complimentary POWER SessionWith Rubi.ai, you'll experience cutting-edge technology, research-driven insights, and efficient content delivery.email: melinda@empowere...
What is death anxiety? We spend the first 15 minutes of the podcast addressing this question. And maybe this was unfair to our guests, the fabulous dynamic duo of palliative psychiatrists Dani Chammas and Keri Brenner (listen to their prior podcasts on therapeutic presence and the angry patient). After all, we invited them on to our podcast to discuss death anxiety, then Eric and I immediately questioned if death anxiety was the best term for what we want to discuss! Several key points stood out to me from this podcast, your key points may differ: The “anxiety” in “death anxiety” is not a pathological phenomenon or a DSM diagnosis; it references an existential concern that is fundamental to the human experience . To me,” awareness of mortality” might be a better term, but in fairness, the idea of “death anxiety” was coined well before the formal establishment of “anxiety disorders.” The ways in which death anxiety manifests in our patient's choices and behaviors varies tremendously, and our responses as clinicians must be individualized. There is no “one size fits all” approach. In one example Dani discusses, a pain level of 1.5/10 might be overwhelming, because for a patient in remission from cancer any pain might signal return of cancer. Some manifestations of death anxiety can be debilitating, others lead to tremendous personal growth, connection to others, and a drive toward finding meaning in their illness experience. Death anxiety impacts us as clinicians, not only through countertransference, that word that I still can't define (sorry Dani and Keri!), but also through our own unexamined fears about death. As clinicians who regularly care for people who are dying, we might find ourselves becoming “used to” death. Is this a sign that we are inured to the banality of death, and less able to empathize with the death anxiety experienced by our patients or their families? Or could it reflect our acceptance of the finitude of life, prompting us to live in the present moment? Perhaps it is something else entirely. The key is that looking inwards to understanding our own unique relationship with mortality can deepen our ability to authentically accompany the experiences of our patients. I mean, don't fear the reaper, right? Sorry, no cowbell in my version, but you do get my son Kai, home from college, on guitar for the audio only podcast version. Here are some resources for listeners wanting to learn more about this topic: Books: Yalom ID. Existential Psychotherapy. New York, NY: Basic Books; 1980. Yalom ID. Staring at the Sun: Overcoming the Terror of Death. San Francisco, CA: Jossey-Bass; 2008. Solomon S, Greenberg J, Pyszczynski T. The Worm at the Core: On the Role of Death in Life. New York, NY: Random House; 2015. Becker E. The Denial of Death. Free Press; 1973. Articles: Emanuel LL, Solomon S, Chochinov HM, et al. Death Anxiety and Correlates in Cancer Patients Receiving Palliative Care. J Palliat Med. 2023;26(2):235-243. Chochinov HM, McClement SE, Hack TF, et al. Death anxiety and correlates in cancer patients receiving outpatient palliative care. J Palliat Med. 2023;26(12):1404–1410. doi:10.1089/jpm.2022.0052. Clark D. Between hope and acceptance: the medicalisation of dying. BMJ. 2002;324(7342):905–907. doi:10.1136/bmj.324.7342.905. Vess M, Arndt J, Cox CR, Routledge C, Goldenberg JL. The terror management of medical decisions: The effect of mortality salience and religious fundamentalism on support for faith-based medical intervention. J Pers Soc Psychol. 2009;97(2):334–350. Menzies RE, Zuccala M, Sharpe L, Dar-Nimrod I. The effects of psychosocial interventions on death anxiety: A meta-analysis and systematic review of randomized controlled trials. J Anxiety Disord. 2018;59:64–73. doi:10.1016/j.janxdis.2018.09.00 Brown TL, Chown P, Solomon S, Gore G, De Groot JM. Psychosocial correlates of death anxiety in advanced cancer: A scoping review. Psychooncology. 2025;34(1):45–56. doi:10.1002/pon.70068. Tarbi EC, Moore CM, Wallace CL, Beaussant Y, Broden EG, Chammas D, Galchutt P, Gilchrist D, Hayden A, Morgan B, Rosenberg LB, Sager Z, Solomon S, Rosa WE, Chochinov HM. Top Ten Tips Palliative Care Clinicians Should Know About Attending to the Existential Experience. J Palliat Med. 2024 Oct;27(10):1379-1389. doi: 10.1089/jpm.2024.0070. Epub 2024 Mar 28. PMID: 38546453.
Do academics matter in college football? The Dave Hooker Show. Represented by Banks and Jones. Tennessee's Trial Attorneys. Play to win. Why settle? Banks and Jones, led by T. Scott Jones. https://www.banksandjones.com/ Live from the Ted Russell Ford/Lincoln Studio. Ted Russell/Ford Lincoln is your home for the finest vehicles in Knoxville. New and used. East Tennessee's largest Ford and Lincoln Volume dealer Brainerd Golf Course and Brown Acres Golf Course Golf Chattanooga's best public courses. Tee times available! Just click below. https://secure.east.prophetservices.c... Chattanooga Mortgage Congratulations! Your home search just got easier. Buying a home in Chattanooga has never been easier. https://chattmortgage.com/ City Heating and Air 50 years in East Tennessee. Integrity Matters! http://www.cityheatandair.com Commercial Bank Commercial Bank. Member FDIC. Life. Made Better. https://www.cbtn.com/ Hemp House The premier hemp dispensary online with a wide variety, great selection and strict standards. https://hemphousechatt.com/ Use promo code "HOOKED" for 10-percent off. HoundDogs of Knoxville Champions look good in Orange! https://hdknoxville.com/ Joe Neubert Collision Center For nearly 50 years, Neubert Collision Center has been East Tennessee's best choice for quality repair work and fantastic customer service. https://www.joeneubertcollision.com/ National Fitness Center Unmatched value. Limitless options. Begin your fitness journey today! https://nfc1.com/ Peak IV Hydration In South Knoxville and Sevierville. Live your life to the fullest. Hydrate, rejuvenate, and elevate your health with Peak IV Hydration. https://www.peakivhydration.com/ Quality Tire Pros Serving Chattanooga community since 1957. All major brands of tires. Full Service Automotive. Brake, Alignments, Oil Changes and more. https://www.qualitytirepros.com/ Say OTH said “Hey Bo!” Rick Terry Jewelry Designs We want to be your Jeweler! Looking for affordable game-day jewelry. A Tennessee tradition. https://rickterryjewelry.com/ Sports Treasures Carrying Over 5-million Sports Treasures….and so much more! Follow on Facebook for the best sports memorabilia. Daily updates! https://www.facebook.com/SportsTreasuresTn The UPS Store Hardin Valley Helping individuals and small businesses. Wide range of products and services. Locally owned and operated. https://locations.theupsstore.com/tn/knoxville/10629-hardin-valley-rd WorkTrux They are all about trucks. Right truck. Right place. Right time. https://worktruxllc.com/ Workout Anytime Offers affordable fitness with high-quality equipment whenever you want it. Fitness that fits your life means there's no excuse, just results. https://workoutanytime.com/ooltewah/
Do academics matter in college football? The Dave Hooker Show. Represented by Banks and Jones. Tennessee's Trial Attorneys. Play to win. Why settle? Banks and Jones, led by T. Scott Jones. https://www.banksandjones.com/ Live from the Ted Russell Ford/Lincoln Studio. Ted Russell/Ford Lincoln is your home for the finest vehicles in Knoxville. New and used. East Tennessee's largest Ford and Lincoln Volume dealer Brainerd Golf Course and Brown Acres Golf Course Golf Chattanooga's best public courses. Tee times available! Just click below. https://secure.east.prophetservices.c... Chattanooga Mortgage Congratulations! Your home search just got easier. Buying a home in Chattanooga has never been easier. https://chattmortgage.com/ City Heating and Air 50 years in East Tennessee. Integrity Matters! http://www.cityheatandair.com Commercial Bank Commercial Bank. Member FDIC. Life. Made Better. https://www.cbtn.com/ Hemp House The premier hemp dispensary online with a wide variety, great selection and strict standards. https://hemphousechatt.com/ Use promo code "HOOKED" for 10-percent off. HoundDogs of Knoxville Champions look good in Orange! https://hdknoxville.com/ Joe Neubert Collision Center For nearly 50 years, Neubert Collision Center has been East Tennessee's best choice for quality repair work and fantastic customer service. https://www.joeneubertcollision.com/ National Fitness Center Unmatched value. Limitless options. Begin your fitness journey today! https://nfc1.com/ Peak IV Hydration In South Knoxville and Sevierville. Live your life to the fullest. Hydrate, rejuvenate, and elevate your health with Peak IV Hydration. https://www.peakivhydration.com/ Quality Tire Pros Serving Chattanooga community since 1957. All major brands of tires. Full Service Automotive. Brake, Alignments, Oil Changes and more. https://www.qualitytirepros.com/ Say OTH said “Hey Bo!” Rick Terry Jewelry Designs We want to be your Jeweler! Looking for affordable game-day jewelry. A Tennessee tradition. https://rickterryjewelry.com/ Sports Treasures Carrying Over 5-million Sports Treasures….and so much more! Follow on Facebook for the best sports memorabilia. Daily updates! https://www.facebook.com/SportsTreasuresTn The UPS Store Hardin Valley Helping individuals and small businesses. Wide range of products and services. Locally owned and operated. https://locations.theupsstore.com/tn/knoxville/10629-hardin-valley-rd WorkTrux They are all about trucks. Right truck. Right place. Right time. https://worktruxllc.com/ Workout Anytime Offers affordable fitness with high-quality equipment whenever you want it. Fitness that fits your life means there's no excuse, just results. https://workoutanytime.com/ooltewah/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prevalence and Correlates of Lipoprotein(a) Testing in a Diverse Cohort of U.S. Adults.
In this episode, Journal of Prosthetics and Orthotics editor-in-chief Dr. Steve Gard speaks with Megan Grunst, MPO, a prosthetic resident at the Minneapolis VA and incoming orthotic resident at Orthotic Care Services. They discuss her recent research on the psychosocial and behavioral outcomes associated with carbon fiber custom dynamic orthoses and an intensive rehabilitation program. The conversation explores how psychological resilience influences long-term device use and patient improvement. The study underscores the critical role of integrating psychological skills reinforcement into rehabilitation to enhance outcomes and patient adherence. Show notes JPO article: Psychosocial Correlates and Behavioral Response to a Carbon Fiber Orthosis and Intensive Rehabilitation Program O&P Research Insights is produced by Association Briefings.
Presented by StrangeBrew Coffeehouse, TraxPlus, Maroon & Co, and Pip Printing and Signs - Nothing is a guarantee from a wins perspective, but the investment into baseball is a definite in Starkville
In this episode of the FIT40 podcast, we dive deep into the most important numbers to focus on to get fit and stay fit for life when it comes to lifestyle management. We cover key health metrics like blood work, cardio, and strength standards that can have a profound impact on your overall wellbeing. Discover practical tips to optimize your cholesterol, blood pressure, A1C, and waist circumference - all essential markers for longevity. Plus, learn science-backed exercise guidelines to improve your cardiac health and build functional strength. This comprehensive guide provides the roadmap to take control of your fitness and wellness at 40 and beyond.FIT40 LINKS:Toned In 20 Workouts: https://fit40-online-coaching.kit.com/1f640492ffBook Your Free Nutrition Assessment: https://calendly.com/coachfitzz/assessmentFIT40 Coaching Info & Application: https://fit40coaching.my.canva.site/applicationFIT40 Family Facebook Group: https://www.facebook.com/groups/fit40familyAFFILIATE LINKS:Try Tonal for 30 Days Risk Free: https://tonal.sjv.io/FIT40Get 10% Off The Genius Protein Shot: https://www.geniusshot.com/?ref=BRYAN_FIT40&transaction_id=10214dd14c839e450a4423af7b1f8eCONNECT WITH ME ONLINEFacebook: https://www.facebook.com/bryan.fitzsimmonsInstagram: https://www.instagram.com/coach_fitzz/Tiktok: https://www.tiktok.com/@coach_fitzz?is_from_webapp=1&sender_device=pcYoutube: https://www.youtube.com/@bryan_fit40CITATIONSMile Run Standards – Citations & SourcesBlair SN, et al. (1996).Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women. JAMA.▸ Demonstrates strong correlation between cardiorespiratory fitness and mortality.American College of Sports Medicine (ACSM)Guidelines for Exercise Testing and Prescription, 10th ed.▸ Provides normative values for VO₂ max and field tests like the 1-mile run.Cooper KH (1968).A means of assessing maximal oxygen intake. Correlation between field and treadmill testing. JAMA.▸ Foundational study introducing the Cooper test and correlating running distance/time to aerobic capacity.10-Mile Bike Standards – Citations & SourcesCooper InstituteThe Cooper Test Manual (Bike variant).▸ Adaptation of the original Cooper test for stationary and road bikes.Kodama S, et al. (2009).Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events. JAMA.Ainsworth BE, et al. (2011).Compendium of Physical Activities: Classification of energy costs of human physical activities.▸ Supports METs estimation for cycling time trials.British Cycling Time Trial Norms▸ Competitive amateur cycling data used for benchmarking 10-mile efforts.Push-Up Standards – Citations & SourcesYang J, et al. (2019).Association Between Push-up Exercise Capacity and Future Cardiovascular Events Among Active Adult Men. JAMA Network Open.▸ Men completing ≥40 push-ups had dramatically lower cardiovascular event risk.ACSM & NSCA Normative DataACSM's Fitness Assessment ManualNSCA's Essentials of Strength Training and Conditioning▸ Provide age- and sex-specific push-up standards.Kraschnewski JL, et al. (2013).Is strength training associated with mortality benefits? Prev Med.Chin-Ups / Inverted Rows – Citations & SourcesRantanen T, et al. (1999).Midlife muscle strength and human longevity up to age 100 years. J Gerontol A Biol Sci Med Sci.▸ Strength and functional movement as predictors of longevity.ACSM Guidelines & NSCA Standards▸ Norms for bodyweight strength tasks including pull-ups and rows.Army Physical Fitness Test (APFT) & USMC Standards▸ Used to create practical strength thresholds for chin-ups by age/sex.Fagan JM, et al. (2020).Maximal upper-body strength and pull-up performance in physically active adults.▸ Correlates pull-up performance with upper body strength and endurance.Reverse Lunge Standards – Citations & SourcesSchoenfeld BJ, et al. (2016).Resistance training volume enhances muscle hypertrophy. J Strength Cond Res.Cook G. (2010).Movement: Functional Movement Systems.▸ Assesses quality and asymmetry in single-leg patterns like lunges.Kraemer WJ & Ratamess NA. (2004).Fundamentals of resistance training: progression and exercise prescription. Med Sci Sports Exerc.ACSM's Position Stand on Resistance Training for Healthy Adults▸ Confirms efficacy and safety of loaded single-leg exercises for aging resilience.Functionally-relevant studies on fall risk and lower-body strengthHughes VA, et al. (2001). Age-related changes in strength and performance. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit bryanfitzsimmon.substack.com
In this JCO Article Insights episode, host Michael Hughes summarizes "Co-Occurrence of Cytogenetic Abnormalities and High-Risk Disease in Newly Diagnosed and Relapsed/Refractory Multiple Myeloma" by Kaiser et al, published February 18, 2025, followed by an interview with JCO Associate Editor Suzanne Lentzsch. Transcript Michael Hughes: Welcome to this episode of JCO Article Insights. This is Michael Hughes, JCO's editorial fellow. Today I have the privilege and pleasure of interviewing Dr. Suzanne Lentzsch on the “Co-Occurrence of Cytogenetic Abnormalities and High-Risk Disease in Newly Diagnosed and Relapsed/Refractory Multiple Myeloma” by Dr. Kaiser and colleagues. At the time of this recording, our guest has disclosures that will be linked in the transcript. The urge to identify patients with aggressive disease, which is the first step in any effort to provide personalized medical care, is intuitive to physicians today. Multiple myeloma patients have experienced heterogeneous outcomes since we first started characterizing the disease. Some patients live for decades after treatment. Some, irrespective of treatment administered, exhibit rapidly relapsing disease. We term this ‘high-risk myeloma'. The Durie-Salmon Risk Stratification System, introduced in 1975, was the first formal effort to identify those patients with aggressive, high-risk myeloma. However, the introduction of novel approaches in therapeutic agents—autologous stem cell transplantation with melphalan conditioning, proteasome inhibitors like bortezomib, or immunomodulatory drugs like lenalidomide—rendered the Durie-Salmon system a less precise predictor of outcomes. The International Staging System in 2005, predicated upon the burden of disease as measured by beta-2 microglobulin and serum albumin, was the second attempt at identifying high-risk myeloma. It was eventually supplanted by the Revised International Staging System (RISS) in 2015, which incorporated novel clinical and cytogenetic markers and remains the primary way physicians think about the risk of progression or relapse in multiple myeloma. Much attention has been focused on the canonically high-risk cytogenetic abnormalities in myeloma, typically identified by fluorescence in situ hybridization: translocation t(4;14), translocation t(14;16), translocation t(14;20), and deletion of 17p. Much attention also has been focused on the fact that intermediate-risk disease, as defined by the RISS, has been shown to be a heterogeneous subgroup in terms of survival outcomes. The RISS underwent revision in 2022 to account for such heterogeneity and has become the R2-ISS, published here in the Journal of Clinical Oncology first in 2022. Translocations t(14;16) and t(14;20) were removed, and gain or amplification of 1q was added. Such revisions to core parts of a modern risk-stratification system reflect the fact that myeloma right now is in flux, both in treatment paradigms and risk-stratification systems. The field in recent years has undergone numerous remarkable changes, from the advent of anti-CD38 agents to the introduction of cellular and bispecific therapies, to the very technology we use to investigate genetic lesions. The major issue is that we're seeing numerous trials using different criteria for the definition of high-risk multiple myeloma. This is a burgeoning problem and speaks very much now to a critical need for an effort to consolidate all these criteria on at least cytogenetic lesions as we move into an era of response-adapted treatment strategies. The excellent article by Kaiser and colleagues, published in the February 2024 edition of the JCO, does just that in a far-ranging meta-analysis of data from 24 prospective therapeutic trials. All 24 trials were phase II or III randomized controlled trials for newly diagnosed and relapsed/refractory multiple myeloma. The paper takes a federated analysis approach: participants provided summaries and performed prespecified uniform analyses. The high-risk cytogenetic abnormalities examined were translocation t(4;14), gain or amplification of 1q, deletion of 17p, and translocation t(14;16), if included in the original trials. All of these were collected into zero, single, or double-hit categories, not unlike the system currently present in diffuse large B-cell lymphomas. The outcomes studied were progression-free survival and overall survival, with these analyses adhering to modified ITT principles. The authors also performed prespecified subgroup analyses in the following: transplant-eligible newly diagnosed myeloma, transplant non-ineligible newly diagnosed myeloma, and relapsed/refractory myeloma. They, in addition, described heterogeneity by the I2 statistic, which, if above 50%, denotes substantial heterogeneity by the Cochrane Review Handbook, and otherwise performed sensitivity analyses and assessed bias to confirm the robustness of their results. In terms of those results, looking at the data collected, there was an appropriate spread of anti-CD38-containing and non-containing trials. 7,724 patients were evaluable of a total 13,926 enrolled in those 24 trials: 4,106 from nine trials in transplant-eligible myeloma, 1,816 from seven trials in transplant non-ineligible myeloma, and 1,802 from eight trials in relapsed/refractory disease. ISS stage for all patients was relatively evenly spread: stage I, 34.5%; stage II, 37%; stage III, 24%. In terms of high-risk cytogenetic lesions, double-hit disease was present in 13.8% of patients, and single-hit disease was present in 37.4%. In terms of outcomes, Kaiser and colleagues found a consistent separation in survival outcomes when the cohort was stratified by the number of high-risk cytogenetic lesions present. For PFS, the hazard ratio was for double-hit 2.28, for single-hit 1.51, without significant heterogeneity. For overall survival, the hazard ratio was for double-hit disease 2.94, single-hit disease 1.69, without significant heterogeneity except in patients with double-hit disease at 56.5%. By clinical subgroups, hazard ratios remained pretty consistent with the overall cohort analysis. In transplant-eligible newly diagnosed myeloma, the hazard ratio for progression is 2.53, overall survival 4.17. For transplant non-ineligible, 1.97 progression, 2.31 mortality. Relapsed/refractory disease progression 2.05, overall mortality 2.21, without significant heterogeneity. Of trials which started recruitment since 2015, that is to say, since daratumumab was FDA approved and thus since an anti-CD38 agent was incorporated into these regimens, analysis revealed the same results, with double-hit myeloma still experiencing worse survival by far of the three categories analyzed. Risk of bias overall was low by advanced statistical analysis. In terms of subgroup analysis, double-hit results for transplant-eligible newly diagnosed myeloma may have been skewed by smaller study effects, where the upper bound of the estimated hazard ratio for mortality reached into the 15 to 20 range. In conclusion, from a massive amount of data comes a very elegant way to think about the role certain cytogenetic abnormalities play in multiple myeloma. A simple number of lesions - zero, one, or at least two - can risk-stratify. This is a powerful new prognostic biomarker candidate and, somewhat soberingly, also may confirm, or at least suggests, that anti-CD38 agents are unable to overcome the deleterious impact of certain biologic characteristics of myeloma. Where do we go from here? This certainly needs further a priori prospective validation. This did not include cellular therapies. The very scale at which this risk-stratification system operates, agnostic to specific genetic lesion, let alone point mutations, lends itself also to further exploration. And to discuss this piece further, we welcome the one and only Dr. Suzanne Lentzsch to the episode. Dr. Lentzsch serves as an associate editor for JCO and is a world-renowned leader at the bleeding edge of plasma cell dyscrasia research. Dr. Lentzsch, there are several new investigations which suggest that translocation t(4;14), for example, is itself a heterogeneous collection of patients. There are other studies which suggest that point mutations in oncogenes like TP53, which were not assessed in Kaiser et al., carry substantial detrimental impact. Is this classification system - no-hit, single-hit, double-hit - too broad a look at tumor genetics? And how do you think we will end up incorporating ever more detailed investigations into the genetics of multiple myeloma moving forward? Dr. Suzanne Lentzsch: Michael, first of all, excellent presentation of that very important trial. Great summary. And of course, it's a pleasure to be here with JCO and with you to discuss that manuscript. Let me go back a little bit to high-risk multiple myeloma. I think over the last years, we had a lot of information on what is high-risk multiple myeloma, and I just want to mention a couple of things, that we separate not only cytogenetically high-risk multiple myeloma, we also have functional high-risk multiple myeloma, with an early relapse after transplant, within 12 months, or two years after start of treatment for the non transplant patients, which is difficult to assess because you cannot decide whether this is a high-risk patient before you start treatment. You only know that in retrospective. Other forms of high-risk: extramedullary disease, circulating tumor cells/plasma cell dyscrasia, patients who never achieve MRD positivity, extramedullary multiple myeloma, or even age and frailty is a high risk for our patients. Then we have gene expression and gene sequencing. So there is so much information currently to really assess what is high-risk multiple myeloma, that is very difficult to find common ground and establish something for future clinical trials. So what Dr. Kaiser did was really to develop a very elegant system with information we should all have. He used four factors: translocation t(14;16), t(4;14), gain or amplification of 1q, and deletion of 17p. Of course, this is not the entire, I would say, information we have on high risk, but I think it's a good standard. It's a very elegant system to really classify a standard single-hit, double-hit, high-risk multiple myeloma, which can be used for all physicians who treat multiple myeloma, and especially, it might also work in resource-scarce settings. So, ultimately, I think that system is an easy-to-use baseline for our patients and provides the best information we can get, especially with a baseline, in order to compare clinical trials or to compare any data in the future. Michael Hughes: Thank you, Dr. Lentzsch. To the point that you made about this isn't the full story. There does, as you said, exist this persistent group of functional high-risk multiple myeloma where we see standard-risk cytogenetics, but these patients ultimately either exhibit primary refractory disease or very early relapse despite aggressive, standard aggressive treatment. How do you see risk-stratification systems incorporating other novel biomarkers for such patients? Is it truly all genetic? Or is next-generation sequencing, gene expression profiling, is that the answer? Or is there still a role for characterizing tumor burden? Dr. Suzanne Lentzsch: Excellent question, Michael, and I wish I would have the glass ball to answer that question. I see some problems with the current approach we have. First of all, to do the cytogenetics, you need good material. You only detect and identify what you have. If the bone marrow is of low quality, you have mainly peripheral blood in your bone marrow biopsy, you might not really fully have a representation of all cytogenetic changes in your bone marrow. So I think with a low-quality sample, that you might miss one or the other really cytogenetic high risk. So, having said this, I think circulating tumor cells, that might be something we will look into in the future, because circulating tumor cells are readily available, can be assessed without doing a bone marrow biopsy. And what is even more exciting, in addition to the circulating tumor cells or plasma cells, using them is next-generation sequencing. I think at the moment, we are more in a collection phase where we really try to correlate sequencing with our cytogenetics and especially to establish next-generation sequencing in all of our patients. But I think after that collection phase, maybe in the future, collecting peripheral blood and doing sequencing on peripheral blood samples might be the way to go. In addition, I don't want to forget the imaging. We started with a skeletal survey, and we know that you probably need to lose 30% of the bone before you see a lesion at all. So having imaging, such as diffusion-weighted imaging, whole-body MRI, is also, together with sequencing of the tumor cells, a step into the right direction. Michael Hughes: Thank you, Dr. Lentzsch. Bringing this back to the article at hand, how has Kaiser et al. changed the way we discuss myeloma with patients in the exam room? Dr. Suzanne Lentzsch: I think we have more data on hand. So far, we talked about standard risk and high risk, but I think right now, with a very simple system, we can go into the room and we can tell the patient, "Listen, you don't have any of those cytogenetic abnormalities. I think you have a standard risk. We might give you a simple maintenance treatment with Revlimid." But we might also go into the room and say, "I'm really concerned. You have so-called double-hit multiple myeloma. You have high-risk and at least two of those abnormal cytogenetics which we discussed, and I think you need a more intense maintenance treatment, for instance, double maintenance." I think we know that a high-risk multiple myeloma can be brought into a remission, but the problem that we have is to keep those patients into a remission. So, I think a more intense treatment, for instance, with a double maintenance, or with consolidation after transplant, and a longer and more intense treatment is justified in patients who have that truly high-risk multiple myeloma described here. Michael Hughes: Dr. Lentzsch, thank you so much for your time and your wisdom. Dr. Suzanne Lentzsch: My pleasure. Thank you for having me. Michael Hughes: Listeners, thank you for listening to JCO Article Insights. Please come back for more interviews and article summaries, and be sure to leave us a rating and review so others can find our show. For more podcasts and episodes from ASCO, please visit ASCO.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
Thorin and Peter Dun are joined by veteran coach Dan Dan to discuss G2 struggling in LEC and their potential to miss MSI, what it takes to build a winning team culture in League of Legends esports, the success of the Madrid homestand for MKOI, Nisqy's strange performance, and more!
Here are 3 big things you need to know— One — Polls will be open in Wisconsin and Florida today in what's being seen as a national political power struggle. In Wisconsin there's a state supreme court election, and Florida voters will decide two pivotal vacant House seats that could shift the balance of power nationally. Both sides see the races as a referendum on the direction of the country since Donald Trump's election victory. Two ---- The bodies of three of the four missing U.S. Army soldiers in Lithuania have been found. The soldiers went missing during a training mission last week. The M88 Hercules armored recovery vehicle they were in was lifted out of a swamp earlier today. The search continues for the fourth soldier. And number three — A recent study finds that a lack of sleep can lead to an increased risk of developing Alzheimer's disease. The lead author of the study from Yale School of Medicine says if the brain doesn't spend sufficient time in deep sleep it can lead to shrinkages in certain parts of the brain affecting specific functions over time. Adults typically need up to eight hours of sleep a night.
In This Episode: Dr. Jeremy Lucabaugh, Tom Bradshaw, Lee Crowson, Dr. Emi Barresi, Nic Krueger, LindaAnn Rogers, Dr. Pamela Maurer I/O Job Hunt Course: https://www.seboc.com/job Visit us https://www.seboc.com/ Follow us on LinkedIn: https://bit.ly/sebocLI Join an open-mic event: https://www.seboc.com/events References: Johnson, R. E., Silverman, S. B., Shyamsunder, A., Swee, H. Y., Rodopman, O. B., Cho, E., & Bauer, J. (2010). Acting superior but actually inferior?: Correlates and consequences of workplace arrogance. Human Performance, 23(5), 403-427. Silverman, S. B., Johnson, R. E., McConnell, N., & Carr, A. (2012). Arrogance: A formula for leadership failure. The Industrial-Organizational Psychologist, 50(1), 21-28. The 30 Most Influential Industrial and Organizational Psychologists Alive Today. Retrieved from https://www.humanresourcesmba.net/30-most-influential-industrial-and-organizational-psychologists-alive-today/
Rebroadcast: this episode was originally released in November 2022.Is war in long-term decline? Steven Pinker's The Better Angels of Our Nature brought this previously obscure academic question to the centre of public debate, and pointed to rates of death in war to argue energetically that war is on the way out.But that idea divides war scholars and statisticians, and so Better Angels has prompted a spirited debate, with datasets and statistical analyses exchanged back and forth year after year. The lack of consensus has left a somewhat bewildered public (including host Rob Wiblin) unsure quite what to believe.Today's guest, professor in political science Bear Braumoeller, is one of the scholars who believes we lack convincing evidence that warlikeness is in long-term decline. He collected the analysis that led him to that conclusion in his 2019 book, Only the Dead: The Persistence of War in the Modern Age.Links to learn more, highlights, and full transcript.The question is of great practical importance. The US and PRC are entering a period of renewed great power competition, with Taiwan as a potential trigger for war, and Russia is once more invading and attempting to annex the territory of its neighbours.If war has been going out of fashion since the start of the Enlightenment, we might console ourselves that however nerve-wracking these present circumstances may feel, modern culture will throw up powerful barriers to another world war. But if we're as war-prone as we ever have been, one need only inspect the record of the 20th century to recoil in horror at what might await us in the 21st.Bear argues that the second reaction is the appropriate one. The world has gone up in flames many times through history, with roughly 0.5% of the population dying in the Napoleonic Wars, 1% in World War I, 3% in World War II, and perhaps 10% during the Mongol conquests. And with no reason to think similar catastrophes are any less likely today, complacency could lead us to sleepwalk into disaster.He gets to this conclusion primarily by analysing the datasets of the decades-old Correlates of War project, which aspires to track all interstate conflicts and battlefield deaths since 1815. In Only the Dead, he chops up and inspects this data dozens of different ways, to test if there are any shifts over time which seem larger than what could be explained by chance variation alone.In a nutshell, Bear simply finds no general trend in either direction from 1815 through today. It seems like, as philosopher George Santayana lamented in 1922, "only the dead have seen the end of war."In today's conversation, Bear and Rob discuss all of the above in more detail than even a usual 80,000 Hours podcast episode, as well as:Why haven't modern ideas about the immorality of violence led to the decline of war, when it's such a natural thing to expect?What would Bear's critics say in response to all this?What do the optimists get right?How does one do proper statistical tests for events that are clumped together, like war deaths?Why are deaths in war so concentrated in a handful of the most extreme events?Did the ideas of the Enlightenment promote nonviolence, on balance?Were early states more or less violent than groups of hunter-gatherers?If Bear is right, what can be done?How did the 'Concert of Europe' or 'Bismarckian system' maintain peace in the 19th century?Which wars are remarkable but largely unknown?Chapters:Cold open (00:00:00)Rob's intro (00:01:01)The interview begins (00:05:37)Only the Dead (00:08:33)The Enlightenment (00:18:50)Democratic peace theory (00:28:26)Is religion a key driver of war? (00:31:32)International orders (00:35:14)The Concert of Europe (00:44:21)The Bismarckian system (00:55:49)The current international order (01:00:22)The Better Angels of Our Nature (01:19:36)War datasets (01:34:09)Seeing patterns in data where none exist (01:47:38)Change-point analysis (01:51:39)Rates of violent death throughout history (01:56:39)War initiation (02:05:02)Escalation (02:20:03)Getting massively different results from the same data (02:30:45)How worried we should be (02:36:13)Most likely ways Only the Dead is wrong (02:38:31)Astonishing smaller wars (02:42:45)Rob's outro (02:47:13)Producer: Keiran HarrisAudio mastering: Ryan KesslerTranscriptions: Katy Moore
Our conversation with Nadia Bevan continues our series profiling research about women's football. Angela Christian-Wilkes and Nadia delve into Nadia's ethnographic research on developing a women's football team at a club in Melbourne. We discuss the structures that include and exclude within community sport, building inclusive practices, and the messiness of insider research. Nadia is an early career researcher specialising in the barriers and enablers of access to sport for a range of groups, including women, girls, youth and the LGBTQIA+ community. She completed a PhD in Education at Monash University, looking at weight stigma as a barrier to physical activity. The Short Corner is a The Far Post's home for all things interesting, different and fun that don't fit under our usual programming of women's football analysis and news. Paper discussed: Bevan, N., Jeanes, R., & Truskewycz, H. (2023). Spatial justice in the development of a women's football team in Melbourne, Australia; an ethnographic study. Gender, Place & Culture, 1–23. https://doi.org/10.1080/0966369X.2023.2201401 Article about the project: https://lens.monash.edu/@nadia-bevan/2023/07/12/1385747/the-world-cup-legacy-how-can-we-create-sustainable-participation-for-girls-and-womens-football Ruth Jeanes' team's work on informal sport: https://www.monash.edu/education/research/projects/informal-sport-as-a-health-and-social-resource/team Papers published from Nadia's PhD: Bevan, N., O'Brien, C. K. S., Latner, J. D., Vandenberg, B., Jeanes, R., & Lin, C.-Y. (2023). The Relationship Between Weight Stigmatization, Avoidance, Enjoyment and Participation in Physical Activity and Sport, and Psychological Distress. American Journal of Health Behavior, 47(2), 360–368. https://doi.org/10.5993/AJHB.47.2.15 Bevan, N., O'Brien, K. S., Latner, J. D., Lin, C.-Y., Vandenberg, B., Jeanes, R., & Fung, X. C. C. (2022). Weight Stigma and Avoidance of Physical Activity and Sport: Development of a Scale and Establishment of Correlates. International Journal of Environmental Research and Public Health, 19(23), 16370. https://doi.org/10.3390/ijerph192316370 Bevan, N., O'Brien, K. S., Lin, C.-Y., Latner, J. D., Vandenberg, B., Jeanes, R., Puhl, R. M., Chen, I.-H., Moss, S., & Rush, G. (2021). The Relationship between Weight Stigma, Physical Appearance Concerns, and Enjoyment and Tendency to Avoid Physical Activity and Sport. International Journal of Environmental Research and Public Health, 18(19), 9957. https://doi.org/10.3390/ijerph18199957 Follow Nadia's Twitter [https://x.com/BevanNadia] and reach out at nadia.bevan@monash.edu Follow The Far Post on Twitter, Facebook, and Instagram. Check out espn.com.au or download the ESPN App. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on DPD quantification correlates with extracellular volume and disease severity in wild-type transthyretin cardiac amyloidosis.
Episode: August 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Dana Mukamel, PhD; Barbara Resnick, PhD, CRNP (co-editor-in-chief) In This Episode: In this episode, host Karl Steinberg, MD, CMD, and co-editor-in-chief Barbara Resnick, PhD, CRNP, will talk with Dana Mukamel, PhD, about her work entitled, The Relationship Between Nursing Home Staffing and Health Outcomes Revisited. In addition to Dr. Mukamel's paper, Drs. Steinberg and Resnick will review three additional articles. Articles Referenced: The Relationship between Nursing Home Staffing and Health Outcomes Revisited How Do We Achieve Person-Centered Care across Health Care Settings? Expanding Ideological Perspectives into Practice to Advance Person-Centered Care External Validation and Further Exploration of Fall Prediction Models Based on Questionnaires and Daily-Life Trunk Accelerometry Prevalence and Correlates of Antipsychotic Medication Use in Oregon Assisted Living Date Recorded: August 9, 2024 Available Credit: The American Board of Post-Acute and Long-Term Care Medicine (ABPLM) issues CMD credits for select PALTtalk podcast episodes as follows: Claim CMD Credit
Cassidy Doyle is a Doctoral Candidate in the Aging Studies at the University of South Florida. Her work focuses on cognitive aging, particularly the factors that can be modified to prevent Alzheimer's disease. We delve into her fascinating research on 'super-agers,' individuals aged 80 and above with memory capabilities comparable to much younger people. Cassidy also shares her personal journey, experiences as a teen caregiver, and the findings from her recent publication on the cognitive aging of Hispanic older adults. Tune in to learn more about what contributes to successful aging, the modifiable factors that may help preserve memory and cognitive function, and insightful takeaways to apply to your own brain health. 00:00 Welcome and Introduction to Cassidy Doyle 01:04 Cassidy's Background and Personal Journey 02:07 Discovering Cognitive Aging and Dementia 05:05 Understanding Super Agers 05:52 Identifying and Researching Super Agers 08:49 Cognitive Reserve and Brain Health 13:48 Lifestyle Factors of Super Agers 16:48 Emotional and Psychological Traits of Super Agers 18:50 Cassidy's Recent Research on Hispanic Super Agers 25:55 Implications for Cognitive Aging and Brain Health 27:35 Rapid Fire Questions and Key Takeaways Resources Join the SuperAging Research Program https://www.brain.northwestern.edu/join/SuperAging.html Explore Cassidy Doyle's research paper “Correlates of SuperAging in Two Population-Based Samples of Hispanic Older Adults” online https://academic.oup.com/psychsocgerontology/article/79/6/gbae058/7641658?login=false --- Support this podcast: https://podcasters.spotify.com/pod/show/virtualbrainhealthcenter/support
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An update of our 2020 series, in which we spoke with physicians, researchers, and addicts about the root causes of the crisis — and the tension between abstinence and harm reduction. SOURCES:Gail D'Onofrio, professor and chair of emergency medicine at the Yale School of Medicine and chief of emergency services at Yale-New Haven Health.Keith Humphreys, professor of psychiatry and behavioral sciences at Stanford University.Stephen Loyd, chief medical officer of Cedar Recovery and chair of the Tennessee Opioid Abatement Council.Nicole O'Donnell, certified recovery specialist at the University of Pennsylvania's Center for Addiction Medicine and Policy.Jeanmarie Perrone, professor of emergency medicine at the University of Pennsylvania.Eileen Richardson, restaurant manager. RESOURCES:“Toward Healthy Drug Policy in the United States — The Case of Safehouse,” by Evan D. Anderson, Leo Beletsky, Scott Burris, and Corey S. Davis (The New England Journal of Medicine, 2020).“Buprenorphine Deregulation and Mainstreaming Treatment for Opioid Use Disorder,” by Leo Beletsky, Kevin Fiscella, and Sarah E. Wakeman (JAMA Psychiatry, 2018).“Emergency Department–Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence,” by Gail D'Onofrio, Patrick G. O'Connor, Michael V. Pantalon, Marek C. Chawarski, Susan H. Busch, Patricia H. Owens, Steven L. Bernstein, and David A. Fiellin (JAMA, 2015).“Buprenorphine-Naloxone Therapy In Pain Management,” by Lucy Chen, Kelly Yan Chen, and Jianren Mao (National Institutes of Health, 2014).“Prevalence and Correlates of Street-Obtained Buprenorphine Use Among Current and Former Injectors In Baltimore, Maryland,” by Jacquie Astemborski, Becky L. Genberg, Mirinda Gillespie, Chris-Ellyn Johanson, Gregory D. Kirk, Shruti H. Mehta, Charles R. Schuster, and David Vlahov (U.S. National Library of Medicine National Institutes of Health, 2014).“The Promotion and Marketing of OxyContin: Commercial Triumph, Public Health Tragedy,” by Art Van Zee (U.S. National Library of Medicine National Institutes of Health, 2009). EXTRAS:"Why Is the Opioid Epidemic Still Raging?" series by Freakonomics Radio (2024)."The Opioid Tragedy, Part 1: 'We've Addicted an Entire Generation,'" by Freakonomics Radio (2020).“The Truth About the Vaping Crisis,” by Freakonomics Radio (2019).
The Evidence Based Chiropractor- Chiropractic Marketing and Research
In today's episode, we've got some compelling new research from the European Spine Journal focusing on thoracolumbar fascia, chronic low back pain, and idiopathic lumbar scoliosis. We'll dive into how ultrasound technology is used to uncover critical findings that could impact chiropractic practices worldwide.Episode Notes: Thoracolumbar fascia and chronic low back pain in idiopathic lumbar scoliosis: an ultrasonographic studyThe Best Objective Assessment of the Cervical Spine- Provide reliable assessments and exercises for Neuromuscular Control, Proprioception, Range of Motion, and Sensorimotor-Integration. Learn more at NeckCare.comInterested in ShockWave technology? I built a practice using StemWave and can't recommend it enough. Learn more at- https://gostemwave.com/theevidencebasedchiropractor Patient Pilot by The Smart Chiropractor is the fastest, easiest to generate weekly patient reactivations on autopilot…without spending any money on advertising. Click here to schedule a call with our team.Our members use research to GROW their practice. Are you interested in increasing your referrals? Discover the best chiropractic marketing you aren't currently using right here!
This day in history. Lizzo says she is stepping out of the limelight. Duji understands Lizzo's frustrations. Could you take on a house cat? Easter weekend shenanigans in Amish country. If JLR won the lottery he would buy a $200k house. A study was done analyzing intelligence in men and how it correlates to their penis size. Man admits to his husband that he killed a person years ago. Dieter wouldn't rat out his spouse. Date night and fun at the bar with the Laroque family. Fake eclipse glasses are flooding the market. The cat is prohibitng sleep in Miami.
Marketing School - Digital Marketing and Online Marketing Tips
In episode #2698, we explore the concept of masterminds and their potential for success. We begin by examining insights into Sam Ovens, whose highly successful mastermind generated $35 million annually with just five employees. We delve into Ovens' unique approach to his mastermind, which included intimate in-person sessions and virtual events. The discussion then transitions to a tweet by Ross Hudgens, which examines the correlation between specific website features and their impact on search rankings, whether positive or negative. Don't forget to help us grow by subscribing and liking on YouTube! Check out more of Eric's content (Leveling UP YT) and Neil's videos (Neil Patel YT) TIME-STAMPED SHOW NOTES: (00:00) Today's topic: The mastermind that does $35M a year with 5 employees, What correlates with positive or negative search rankings?, Political agendas now affect a company's marketing plan, and more (00:39) Eric explains the unique format of Sam Ovens' mastermind, where participants discuss their problems and share expertise. (03:14) Eric mentions another mastermind that charges $85,000 for a year and a half, targeting a specific industry. (05:01) Neil Patel brings up a tweet by Ross Hudgens about website features that correlate with positive or negative search rankings. (05:40) Eric shares the positive website features that correlate with increased traffic, including first person pronouns and cookie consent. (06:14) Neil expresses skepticism about the impact of adding pronouns to articles on search rankings. (07:13) Eric reveals the four most negative website features that correlate with decreased traffic, including fixed ads and stock images. (08:26) Pronouns likely do not affect website rankings. (09:09) Political issues are impacting marketing decisions. (13:35) Organizations are making drastic changes based on personal beliefs. (15:10) Gemini's prompt for diverse images sparked controversy. (17:00) That's it for today! Don't forget to rate, review, and subscribe! Go to https://www.marketingschool.io to learn more! Leave Some Feedback: What should we talk about next? Please let us know in the comments below Did you enjoy this episode? If so, please leave a short review. Connect with Us: Single Grain
"Quem nunca foi traído é porque não sabe ou ainda será", diz o senso comum. Mas o que a ciência tem a dizer sobre a traição amorosa ou afetiva? Confira a segunda e última parte do papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.> OUÇA (54min 02s)*Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br*PARCERIA: ALURAAprofunde-se de vez: garantimos conhecimento com profundidade e diversidade, para se tornar um profissional em T - incluindo programação, front-end, data science, devops, ux & design, mobile, inovação & gestão.Navegue sua carreira: são mais de 1450 cursos e novos lançamentos toda semana, além de atualizações e melhorias constantes.Conteúdo imersivo: faça parte de uma comunidade de apaixonados por tudo que é digital. Mergulhe na comunidade Alura.Aproveite o desconto para ouvintes Naruhodo no link:alura.tv/naruhodo*REFERÊNCIASThe aftershocks of infidelity: a review of infidelitybased attachment traumahttps://sci-hub.se/https://www.tandfonline.com/doi/abs/10.1080/14681994.2019.1577961?casa_token=CjCskZlCNpwAAAAA:bFF9gyZJATcSAJuDxb8WBgxP51KpSotz_oDBXwcdmohYq5ra_mLj0Q4SkSFP0tiyEwgU3J48ZAzJ5gSelf-reported Big Five personality traits of individuals who have experienced partner infidelityhttps://onlinelibrary.wiley.com/doi/full/10.1111/pere.12315Premarital Precursors of Marital Infidelityhttps://onlinelibrary.wiley.com/doi/full/10.1111/j.1545-5300.2008.00251.xJustifying by degrees: A grounded theory of men's decision-making process in infidelityhttps://onlinelibrary.wiley.com/doi/abs/10.1111/jmft.12663?casa_token=fKPeY5Sy7TIAAAAA:-54x5VT_4OJHVJ4y7TU2FBYBEpKPbqu1DnkgwBss3C-q0d0kCqpvuRVrbBQ0aipB4GvmBlVP1o_VD0x6Couple healing from infidelity: a deductive qualitative analysis studyhttps://www.tandfonline.com/doi/abs/10.1080/14681994.2022.2086231?casa_token=3lQsqfTATNIAAAAA:0BntwAxXTj6rFEWl0V5o168Kc4-zB_rfwl0F9cul5rD13J14NUuiNWb7GG2tK_zW4MKH6f6Kt4v5tAWhy Did I Cheat on My Partner? Mapping the Motives of Infidelity in Dating Relationships Through the Perpetratorshttps://journals.sagepub.com/doi/full/10.1177/10664807231201629?casa_token=Gx824Y70haQAAAAA%3AKeff71HlAe0ltTXV2CrAOR6t74FDSCqcZSS_nt56EZJB-hoVvEjgaZxO2dg_FZE-kSG2NIl17tUIhACouple healing from infidelity: A grounded theory studyhttps://journals.sagepub.com/doi/full/10.1177/02654075231177874?casa_token=iqwvbGX3O28AAAAA%3AW8WuG_VLq45-Jn1GDGVdlTG2scsUXhSI0HCg4gQ4NqY9kgRi-DSo6j_R0e9yJLB-0yUE_m5WLEzf0AThe Science of Family Systems Theoryhttps://books.google.com.br/books?hl=en&lr=&id=k3QWEAAAQBAJ&oi=fnd&pg=PP1&ots=4IY3oZhr64&sig=f0msyPUWLabyMueBrIFmTkT0I5M&redir_esc=y#v=onepage&q&f=falseRomantic Attachment and Difficulties in Emotion Regulation on Dyadic Adjustment: A Comprehensive Literature Reviewhttps://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2021.723823/fullThe aftershocks of infidelity: a review of infidelity-based attachment traumahttps://www.tandfonline.com/doi/abs/10.1080/14681994.2019.1577961?casa_token=CjCskZlCNpwAAAAA:bFF9gyZJATcSAJuDxb8WBgxP51KpSotz_oDBXwcdmohYq5ra_mLj0Q4SkSFP0tiyEwgU3J48ZAzJ5gPredicting psychological helplessness based on initial maladaptive schemas and coping strategies in women affected by marital infidelityhttps://www.aftj.ir/article_145688.html?lang=enMarital infidelity and Betrayal Experiences: The Role of executive functions and Religious Coping Strategies in Predicting Divorce of Womenhttps://journalppw.com/index.php/jpsp/article/view/2728Erectile dysfunction, suspicious jealousy, and the desire for power in heterosexual romantic coupleshttps://www.sciencedirect.com/science/article/pii/S0191886924000072?casa_token=saOokTlfbgAAAAAA:BIRqVkExZW4uRtERVq1FknldQv2k3sdcZ23CKUbfVtjpRTPtjOnyYozrF0CzcpjOoK9efihDYDoAn investigation of technology's role in coping with infidelityhttps://www.tandfonline.com/doi/abs/10.1080/17459435.2024.2310516?casa_token=7lt3oTJKeQcAAAAA:ZoPwsAM_82bWGJFdCDmYeWzOlnxCi96GFpaTAYTYpDv5ghx_-RZ74TJ93E3BMoEP2IBrCGg9Ocsi4QCoping with Romantic Betrayal: Sex Differences in Responses to Partner Infidelityhttps://journals.sagepub.com/doi/full/10.1177/147470490800600305Infidelity and Its Associated Factors: A Systematic Reviewhttps://academic.oup.com/jsm/article-abstract/16/8/1155/6980608The Effect of Cognitive-Behavioral Group Therapy on Depression and Coping Styles of Women Exposed to Marital Infidelityhttps://womenshealthbulletin.sums.ac.ir/article_45985_8c5a44d177cb0e78d21f7ccb234ff9ef.pdfThe predictors of the traumatic effect of extramarital infidelity on married women: coping strategies, resources, and forgivenesshttps://open.metu.edu.tr/handle/11511/20011Understanding infidelity: Correlates in a national random sample.https://psycnet.apa.org/doiLanding?doi=10.1037%2F0893-3200.15.4.735Extramarital sex: Prevalence and correlates in a national surveyhttps://www.tandfonline.com/doi/abs/10.1080/00224499709551881Alfred Kinsey's 1948 and 1953 Studieshttps://web.archive.org/web/20100726194522/http://www.kinseyinstitute.org/research/ak-data.html2005 Global Sex Survey resultshttps://web.archive.org/web/20080216080708/http://www.durex.com/cm/gss2005result.pdfMen and women show distinct brain activations during imagery of sexual and emotional infidelityhttps://www.sciencedirect.com/science/article/pii/S1053811906006112?casa_token=T3xcBUy8XAoAAAAA:RgiyM7Q8evpb9kLzC2_Sb22k0qFPwbhRnEJiVqkBDo2aQ-gEx8Ti6_St27yfILC2u8wXPzKc9gYMeasuring paternal discrepancy and its public health consequenceshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1733152/pdf/v059p00749.pdfNaruhodo #216 - Por que sentimos ciúmes?https://www.youtube.com/watch?v=oCSVc17yJ-gNaruhodo #399 - Assistir à pornografia vicia?https://www.youtube.com/watch?v=vByA0QVSOb8Naruhodo #403 - Por que temos fetiches sexuais?https://www.youtube.com/watch?v=C-ET1nIP6WMNaruhodo #406 - As fases do luto têm validade científica?https://www.youtube.com/watch?v=VltGGsSfNsINaruhodo #338 - Por que fofocamos?https://www.youtube.com/watch?v=ij9ocesTc50Naruhodo #352 - Por que pedimos desculpas? - Parte 1 de 2https://www.youtube.com/watch?v=jVzZ9dTAgGYNaruhodo #353 - Por que pedimos desculpas? - Parte 2 de 2https://www.youtube.com/watch?v=vvOMB66B5u0Naruhodo #407 - Existe razão sem emoção?https://www.youtube.com/watch?v=qUxluRrHV3ENaruhodo #405 - O que é o infinito?https://www.youtube.com/watch?v=Vdu5LRFKa-MNaruhodo #404 - Por que algumas pessoas gostam de terminar as coisas e outras não?https://www.youtube.com/watch?v=pTSZ--4TKMkNaruhodo #286 - Por que sentimos vergonha? - Parte 1 de 2https://www.youtube.com/watch?v=eDneD9_4rrENaruhodo #287 - Por que sentimos vergonha? - Parte 2 de 2https://www.youtube.com/watch?v=L0K9LE8skyENaruhodo #189 - Por que reviramos os olhos?https://www.youtube.com/watch?v=iJXFS72FDZI*APOIE O NARUHODO PELA PLATAFORMA ORELO!Um aviso importantíssimo: o podcast Naruhodo agora está no Orelo: https://bit.ly/naruhodo-no-oreloE é por meio dessa plataforma de apoio aos criadores de conteúdo que você ajuda o Naruhodo a se manter no ar.Você escolhe um valor de contribuição mensal e tem acesso a conteúdos exclusivos, conteúdos antecipados e vantagens especiais.Além disso, você pode ter acesso ao nosso grupo fechado no Telegram, e conversar comigo, com o Altay e com outros apoiadores.E não é só isso: toda vez que você ouvir ou fizer download de um episódio pelo Orelo, vai também estar pingando uns trocadinhos para o nosso projeto.Então, baixe agora mesmo o app Orelo no endereço Orelo.CC ou na sua loja de aplicativos e ajude a fortalecer o conhecimento científico.https://bit.ly/naruhodo-no-orelo
In this episode, we are joined by Drs Marc Brackett and Niobe Way to discuss the importance of human connection for children, teenagers, and adults. We talk about the significance of supportive relationships for healthy social emotional development, and the potential negative effects of a lack of supportive relationships, including violence and self-harm. Further, Marc and Niobe dive into the topic of relational intelligence and ways in which this can be understood and learned. Finally, we discuss how parents can find ways to be the person their children can turn to and how they can go from passing judgment to being curious role models. To learn more about Dr. Marc Brackett please visit: https://www.marcbrackett.com and howwefeel.org To learn more about Dr. Niobe Way please visit: https://steinhardt.nyu.edu/people/niobe-way and listen to her Ted talk https://www.youtube.com/watch?v=vFsZsn7SRAc To learn more about Dr. Way's research and the movie Close please visit: https://www.latimes.com/entertainment-arts/movies/story/2023-01-27/lukas-dhont-close-oscar-nominee
"Quem nunca foi traído é porque não sabe ou ainda será", diz o senso comum. Mas o que a ciência tem a dizer sobre a traição amorosa ou afetiva? Confira a primeira parte de duas no papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.> OUÇA (49min 16s)*Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br*PARCERIA: ALURAAprofunde-se de vez: garantimos conhecimento com profundidade e diversidade, para se tornar um profissional em T - incluindo programação, front-end, data science, devops, ux & design, mobile, inovação & gestão.Navegue sua carreira: são mais de 1450 cursos e novos lançamentos toda semana, além de atualizações e melhorias constantes.Conteúdo imersivo: faça parte de uma comunidade de apaixonados por tudo que é digital. Mergulhe na comunidade Alura.Aproveite o desconto para ouvintes Naruhodo no link:alura.tv/naruhodo*REFERÊNCIASThe aftershocks of infidelity: a review of infidelitybased attachment traumahttps://sci-hub.se/https://www.tandfonline.com/doi/abs/10.1080/14681994.2019.1577961?casa_token=CjCskZlCNpwAAAAA:bFF9gyZJATcSAJuDxb8WBgxP51KpSotz_oDBXwcdmohYq5ra_mLj0Q4SkSFP0tiyEwgU3J48ZAzJ5gSelf-reported Big Five personality traits of individuals who have experienced partner infidelityhttps://onlinelibrary.wiley.com/doi/full/10.1111/pere.12315Premarital Precursors of Marital Infidelityhttps://onlinelibrary.wiley.com/doi/full/10.1111/j.1545-5300.2008.00251.xJustifying by degrees: A grounded theory of men's decision-making process in infidelityhttps://onlinelibrary.wiley.com/doi/abs/10.1111/jmft.12663?casa_token=fKPeY5Sy7TIAAAAA:-54x5VT_4OJHVJ4y7TU2FBYBEpKPbqu1DnkgwBss3C-q0d0kCqpvuRVrbBQ0aipB4GvmBlVP1o_VD0x6Couple healing from infidelity: a deductive qualitative analysis studyhttps://www.tandfonline.com/doi/abs/10.1080/14681994.2022.2086231?casa_token=3lQsqfTATNIAAAAA:0BntwAxXTj6rFEWl0V5o168Kc4-zB_rfwl0F9cul5rD13J14NUuiNWb7GG2tK_zW4MKH6f6Kt4v5tAWhy Did I Cheat on My Partner? Mapping the Motives of Infidelity in Dating Relationships Through the Perpetratorshttps://journals.sagepub.com/doi/full/10.1177/10664807231201629?casa_token=Gx824Y70haQAAAAA%3AKeff71HlAe0ltTXV2CrAOR6t74FDSCqcZSS_nt56EZJB-hoVvEjgaZxO2dg_FZE-kSG2NIl17tUIhACouple healing from infidelity: A grounded theory studyhttps://journals.sagepub.com/doi/full/10.1177/02654075231177874?casa_token=iqwvbGX3O28AAAAA%3AW8WuG_VLq45-Jn1GDGVdlTG2scsUXhSI0HCg4gQ4NqY9kgRi-DSo6j_R0e9yJLB-0yUE_m5WLEzf0AThe Science of Family Systems Theoryhttps://books.google.com.br/books?hl=en&lr=&id=k3QWEAAAQBAJ&oi=fnd&pg=PP1&ots=4IY3oZhr64&sig=f0msyPUWLabyMueBrIFmTkT0I5M&redir_esc=y#v=onepage&q&f=falseRomantic Attachment and Difficulties in Emotion Regulation on Dyadic Adjustment: A Comprehensive Literature Reviewhttps://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2021.723823/fullThe aftershocks of infidelity: a review of infidelity-based attachment traumahttps://www.tandfonline.com/doi/abs/10.1080/14681994.2019.1577961?casa_token=CjCskZlCNpwAAAAA:bFF9gyZJATcSAJuDxb8WBgxP51KpSotz_oDBXwcdmohYq5ra_mLj0Q4SkSFP0tiyEwgU3J48ZAzJ5gPredicting psychological helplessness based on initial maladaptive schemas and coping strategies in women affected by marital infidelityhttps://www.aftj.ir/article_145688.html?lang=enMarital infidelity and Betrayal Experiences: The Role of executive functions and Religious Coping Strategies in Predicting Divorce of Womenhttps://journalppw.com/index.php/jpsp/article/view/2728Erectile dysfunction, suspicious jealousy, and the desire for power in heterosexual romantic coupleshttps://www.sciencedirect.com/science/article/pii/S0191886924000072?casa_token=saOokTlfbgAAAAAA:BIRqVkExZW4uRtERVq1FknldQv2k3sdcZ23CKUbfVtjpRTPtjOnyYozrF0CzcpjOoK9efihDYDoAn investigation of technology's role in coping with infidelityhttps://www.tandfonline.com/doi/abs/10.1080/17459435.2024.2310516?casa_token=7lt3oTJKeQcAAAAA:ZoPwsAM_82bWGJFdCDmYeWzOlnxCi96GFpaTAYTYpDv5ghx_-RZ74TJ93E3BMoEP2IBrCGg9Ocsi4QCoping with Romantic Betrayal: Sex Differences in Responses to Partner Infidelityhttps://journals.sagepub.com/doi/full/10.1177/147470490800600305Infidelity and Its Associated Factors: A Systematic Reviewhttps://academic.oup.com/jsm/article-abstract/16/8/1155/6980608The Effect of Cognitive-Behavioral Group Therapy on Depression and Coping Styles of Women Exposed to Marital Infidelityhttps://womenshealthbulletin.sums.ac.ir/article_45985_8c5a44d177cb0e78d21f7ccb234ff9ef.pdfThe predictors of the traumatic effect of extramarital infidelity on married women: coping strategies, resources, and forgivenesshttps://open.metu.edu.tr/handle/11511/20011Understanding infidelity: Correlates in a national random sample.https://psycnet.apa.org/doiLanding?doi=10.1037%2F0893-3200.15.4.735Extramarital sex: Prevalence and correlates in a national surveyhttps://www.tandfonline.com/doi/abs/10.1080/00224499709551881Alfred Kinsey's 1948 and 1953 Studieshttps://web.archive.org/web/20100726194522/http://www.kinseyinstitute.org/research/ak-data.html2005 Global Sex Survey resultshttps://web.archive.org/web/20080216080708/http://www.durex.com/cm/gss2005result.pdfMen and women show distinct brain activations during imagery of sexual and emotional infidelityhttps://www.sciencedirect.com/science/article/pii/S1053811906006112?casa_token=T3xcBUy8XAoAAAAA:RgiyM7Q8evpb9kLzC2_Sb22k0qFPwbhRnEJiVqkBDo2aQ-gEx8Ti6_St27yfILC2u8wXPzKc9gYMeasuring paternal discrepancy and its public health consequenceshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1733152/pdf/v059p00749.pdfNaruhodo #216 - Por que sentimos ciúmes?https://www.youtube.com/watch?v=oCSVc17yJ-gNaruhodo #399 - Assistir à pornografia vicia?https://www.youtube.com/watch?v=vByA0QVSOb8Naruhodo #403 - Por que temos fetiches sexuais?https://www.youtube.com/watch?v=C-ET1nIP6WMNaruhodo #406 - As fases do luto têm validade científica?https://www.youtube.com/watch?v=VltGGsSfNsINaruhodo #338 - Por que fofocamos?https://www.youtube.com/watch?v=ij9ocesTc50Naruhodo #352 - Por que pedimos desculpas? - Parte 1 de 2https://www.youtube.com/watch?v=jVzZ9dTAgGYNaruhodo #353 - Por que pedimos desculpas? - Parte 2 de 2https://www.youtube.com/watch?v=vvOMB66B5u0Naruhodo #407 - Existe razão sem emoção?https://www.youtube.com/watch?v=qUxluRrHV3ENaruhodo #405 - O que é o infinito?https://www.youtube.com/watch?v=Vdu5LRFKa-MNaruhodo #404 - Por que algumas pessoas gostam de terminar as coisas e outras não?https://www.youtube.com/watch?v=pTSZ--4TKMkNaruhodo #286 - Por que sentimos vergonha? - Parte 1 de 2https://www.youtube.com/watch?v=eDneD9_4rrENaruhodo #287 - Por que sentimos vergonha? - Parte 2 de 2https://www.youtube.com/watch?v=L0K9LE8skyENaruhodo #189 - Por que reviramos os olhos?https://www.youtube.com/watch?v=iJXFS72FDZI*APOIE O NARUHODO PELA PLATAFORMA ORELO!Um aviso importantíssimo: o podcast Naruhodo agora está no Orelo: https://bit.ly/naruhodo-no-oreloE é por meio dessa plataforma de apoio aos criadores de conteúdo que você ajuda o Naruhodo a se manter no ar.Você escolhe um valor de contribuição mensal e tem acesso a conteúdos exclusivos, conteúdos antecipados e vantagens especiais.Além disso, você pode ter acesso ao nosso grupo fechado no Telegram, e conversar comigo, com o Altay e com outros apoiadores.E não é só isso: toda vez que você ouvir ou fizer download de um episódio pelo Orelo, vai também estar pingando uns trocadinhos para o nosso projeto.Então, baixe agora mesmo o app Orelo no endereço Orelo.CC ou na sua loja de aplicativos e ajude a fortalecer o conhecimento científico.https://bit.ly/naruhodo-no-orelo
References Nutrients. 2021 Feb; 13(2): 413. Advances in Clinical ChemistryVolume 64, 2014, Pages 117-177. Front Physiol. 2020; 11: 796. Int J Mol Sci. 2023 Sep; 24(18): 13942. J Diabetes Investig. 2023. Oct;14(10):1148-1156. Nutrients. 2022 Jun 12;14(12):2438 RNA Biol. 2023; 20(1): 737–749. Clinica Chimica ActaVolume 508, Pages 61-68 Kirwan, Danny. 1971. "Sands of Time" Fleetwood Mac Lp Future Games https://youtu.be/1Jkp34jMeEw?si=fRzdAiA525bHRX5k --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
In this 8th episode of the #MarketingMatters podcast, Ashley Brock meets with Emily Judice (@emilyeatsandchats). They discuss how your health directly ties to your wealth. They talk about the mindset, thoughts, and habits that lead to taking your health and wealth to the next level. Connect with Emily Instagram: @emilyeatsandchats Website: Emily Judice YouTube: Emily's YouTube Connect with Ashley Instagram: @the.ashley.brock Website: ashleybrock.com YouTube: @digitalmarketingmatters Resources: Get Emily's Guide: 3 Shifts to Break Through Your Fat Loss Plateau Grab your tickets for the Marketing Matters Summit on Tuesday, January 9th! Books Emily mentioned: Power of Positive Leadership Slight Edge Business Secrets of the Bible
Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Ability to solve long-horizon tasks correlates with wanting things in the behaviorist sense, published by Nate Soares on November 24, 2023 on The AI Alignment Forum. Status: Vague, sorry. The point seems almost tautological to me, and yet also seems like the correct answer to the people going around saying "LLMs turned out to be not very want-y, when are the people who expected 'agents' going to update?", so, here we are. Okay, so you know how AI today isn't great at certain... let's say "long-horizon" tasks? Like novel large-scale engineering projects, or writing a long book series with lots of foreshadowing? (Modulo the fact that it can play chess pretty well, which is longer-horizon than some things; this distinction is quantitative rather than qualitative and it's being eroded, etc.) And you know how the AI doesn't seem to have all that much "want"- or "desire"-like behavior? (Modulo, e.g., the fact that it can play chess pretty well, which indicates a certain type of want-like behavior in the behaviorist sense. An AI's ability to win no matter how you move is the same as its ability to reliably steer the game-board into states where you're check-mated, as though it had an internal check-mating "goal" it were trying to achieve. This is again a quantitative gap that's being eroded.) Well, I claim that these are more-or-less the same fact. It's no surprise that the AI falls down on various long-horizon tasks and that it doesn't seem all that well-modeled as having "wants/desires"; these are two sides of the same coin. Relatedly: to imagine the AI starting to succeed at those long-horizon tasks without imagining it starting to have more wants/desires (in the "behaviorist sense" expanded upon below) is, I claim, to imagine a contradiction - or at least an extreme surprise. Because the way to achieve long-horizon targets in a large, unobserved, surprising world that keeps throwing wrenches into one's plans, is probably to become a robust generalist wrench-remover that keeps stubbornly reorienting towards some particular target no matter what wrench reality throws into its plans. This observable "it keeps reorienting towards some target no matter what obstacle reality throws in its way" behavior is what I mean when I describe an AI as having wants/desires "in the behaviorist sense". I make no claim about the AI's internal states and whether those bear any resemblance to the internal state of a human consumed by the feeling of desire. To paraphrase something Eliezer Yudkowsky said somewhere: we wouldn't say that a blender "wants" to blend apples. But if the blender somehow managed to spit out oranges, crawl to the pantry, load itself full of apples, and plug itself into an outlet, then we might indeed want to start talking about it as though it has goals, even if we aren't trying to make a strong claim about the internal mechanisms causing this behavior. If an AI causes some particular outcome across a wide array of starting setups and despite a wide variety of obstacles, then I'll say it "wants" that outcome "in the behaviorist sense". Why might we see this sort of "wanting" arise in tandem with the ability to solve long-horizon problems and perform long-horizon tasks? Because these "long-horizon" tasks involve maneuvering the complicated real world into particular tricky outcome-states, despite whatever surprises and unknown-unknowns and obstacles it encounters along the way. Succeeding at such problems just seems pretty likely to involve skill at figuring out what the world is, figuring out how to navigate it, and figuring out how to surmount obstacles and then reorient in some stable direction. (If each new obstacle causes you to wander off towards some different target, then you won't reliably be able to hit targets that you start out aimed towards.) If you're the ...
Have you ever talked to a sociopath? According to the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (or DSM-5), sociopathy is a category of antisocial personality disorder. A sociopath is someone with interior, social, and pathological impairments to their personality. Sociopaths will say anything to get their way, even if that means bending the truth and manipulation. Do you suspect you may be dealing with a sociopath right now? In this video, we present to you some of the things a sociopath would say to help you understand what really goes through their minds. As a disclaimer, we want to note that these phrases alone don't define a sociopath. Language is just a small piece of a larger puzzle. In other words, you may hear a friend or partner use phrases from this list, but that doesn't necessarily make him or her a sociopath. Writer: Tristan Reed Script Manager: Kelly Soong VO: Lily Hu Animator: Zuzia YouTube Manager: Cindy Cheong Join Our Psych2Go Premium Podcast Now! https://psych2go.supercast.com American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders: Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Arlington, VA: American Psychiatric Association, 2013. Eddy, B. (2018). How to Spot a Sociopath in 3 Steps. Psychology Today. Hare R. D. (1993). Without Conscience: The Disturbing World of the Psychopaths Among Us. New York, NY: Guilford Press Johnson, S. A. (2019). Understanding the violent personality: antisocial personality disorder, psychopathy & sociopathy. Forensic Research & Criminology International Journal, 7(2), 76-88. Lilienfeld S. et al. (2014). Correlates of psychopathic personality traits in everyday life: results from a large community survey. Frontiers in Psychology, 5, 740. Perry, C. (2015). The ‘dark traits' of sociopathic leaders. Australian Universities' Review, 51(1), 17-25.
Feeeeeeelings! We've talked about them quite a bit on Baggage Check. But what we haven't talked about yet is something crucial but often overlooked: the way that we feel our emotions, physically. It's virtually impossible to improve how you deal with negative emotions if you don't have a good foundation of understanding how they manifest in your body. And though it's specific to every person, we start with some nearly-universal trends in how people tend to feel certain classic negative emotions. Do you recognize yourself in these?If you want a crash course in how to think about the mind-body connection, or even if you are a practiced mindfulness guru who wants to spend a little time thinking about the different ways that feelings show up in your own personal body, you'll want to listen to today's Baggage Check. Follow Baggage Check on Instagram @baggagecheckpodcast and get sneak peeks of upcoming episodes, give your take on guests and show topics, gawk at the very good boy Buster the Dog, and send us your questions!Here's more on Dr. Andrea Bonior and her book Detox Your Thoughts.Here's more on this podcast, which somehow you already found (thank you!)Credits: Beautiful cover art by Danielle Merity, exquisitely lounge-y original music by Jordan Cooper
Today we welcome to the podcast Veronica Villanueva who has embraced the Finnish concept of "Sisu" and made it her own while overcoming personal difficulties and coming out of it with a deeper level of joy, contentment and inner peace she thought was possible!In this interview with Veronica, you'll discover:-What does the word "Sisu" mean to Veronica?...03:00-Reframe your reality to improve your health and quality of life...04:30-Write a letter to yourself to dispose of negative emotions and bitterness...08:00-Even the most blatant falsehood is true if you believe it to be....13:00-How to connect with Joy on the deepest level possible...17:04-How Veronica reclaimed her personal agency through a recent divorce...22:20-Veronica's advice for those who seek a deeper level of joy in their lives...28:11-And much more...Resources mentioned:Veronica's websiteVeronica's InstagramAbout the guest:Meet Veronica, the founder of Sisu and Yourbadassbelief coach. Despite being given a dire prognosis of less than six months to live with tumors in her brain, liver, and chest, Veronica is a two-time cancer warrior who has not only beaten the odds but is also thriving today.Veronica's mission is to inspire others to live a healthy life, using a #healthylifestyleasmedicine, and to give hope to those who have been affected by cancer. Through her Amazon best-selling book, "The Grace of Cancer," Veronica shares her story of how she discovered her sisu, or stoic determination, tenacity of purpose, grit, bravery, resilience, and hardiness, during her battle with cancer.Through her company, Sisu, Veronica invests in people, helping them discover their own sisu and live a limitless life. She is a beacon of hope and inspiration, showing that despite all the pain and suffering, it is possible to choose happiness and fulfill one's mission. With her unshakable determination and positive attitude, Veronica is living proof that with Sisu, anything is possible.OM HealsQuantum physics reveals that we are 99.9999% energy and only .00001% physical matter. When we flow, move, and balance blocked energies we hold, then our mind, body and soul return to its natural state of well being.We are committed to matching you with the best possible energy meta-cine practitioners to support your wellness with our customized algorithm. After each energy session, we will ask for your feedback on how well we are matchmaking you with energy practitioners so we may serve you as best as we can.Visit om-heals.com to learn more and to get started today!
YouTube Link: https://www.youtube.com/watch?v=t_YMcEPfqCM Sponsors: - Manscaped: Get 20% Off and Free Shipping with the code [TOE] at Manscaped.com. - Brilliant: https://brilliant.org/TOE for 20% off Claudia Passos is an Assistant Professor of Bioethics at NYU studying infant consciousness, Garrett Mindt is a professor of philosophy at Florida Atlantic University focused on novel information-theoretic metaphysics, and Carlos Montemayor is a professor of philosophy whose research focuses on the intersection between philosophy of mind, epistemology and cognitive science. This episode has been released early in an ad-free audio version for TOE members at http://theoriesofeverything.org. - *New* TOE Website (early access to episodes): https://theoriesofeverything.org/ - Patreon: https://patreon.com/curtjaimungal - Crypto: https://tinyurl.com/cryptoTOE - PayPal: https://tinyurl.com/paypalTOE - Twitter: https://twitter.com/TOEwithCurt - Discord Invite: https://discord.com/invite/kBcnfNVwqs - iTunes: https://podcasts.apple.com/ca/podcast... - Pandora: https://pdora.co/33b9lfP - Spotify: https://open.spotify.com/show/4gL14b9... - Subreddit r/TheoriesOfEverything: https://reddit.com/r/theoriesofeveryt... TIMESTAMPS: 00:00:00 Introduction 00:03:56 How aware are infants? 00:08:36 Correlates of consciousness 00:11:16 Trauma in infants 00:17:00 Traditional definitions of consciousness 00:22:05 Animal consciousness 00:26:05 Phenomenal consciousness 00:35:37 “You can't be intelligent if you are not autonomous” 00:37:00 Asymmetric moral considerations 00:41:00 Agency needs vulnerability to work 00:43:20 The borders between biology and machine 00:46:00 Building "mini brains"! 00:58:40 Behavioral markers of consciousness 01:00:10 Should AI be given the same ethical consideration as our human children? 01:05:16 Do infants lack moral standing? 01:08:14 Is analogue consciousness relevant? 01:14:06 What do we mean by “autonomy”? 01:19:00 Outro Learn more about your ad choices. Visit megaphone.fm/adchoices
Article in question: https://bit.ly/3ZhN0b6 _______________________________________ If you appreciate my work and would like to support it: https://subscribestar.com/the-saad-truth https://patreon.com/GadSaad https://paypal.me/GadSaad _______________________________________ This clip was posted earlier today (February 25, 2023) on my YouTube channel as THE SAAD TRUTH_1518: https://youtu.be/XgXqBwH2NJw _______________________________________ My forthcoming book The Saad Truth about Happiness: 8 Secrets for Leading the Good Life is now available for pre-order: https://www.amazon.com/Saad-Truth-about-Happiness-Secrets/dp/1684512603 _______________________________________ Please visit my website gadsaad.com, and sign up for alerts. If you appreciate my content, click on the "Support My Work" button. I count on my fans to support my efforts. You can donate via Patreon, PayPal, and/or SubscribeStar. _______________________________________ Dr. Gad Saad is a professor, evolutionary behavioral scientist, and author who pioneered the use of evolutionary psychology in marketing and consumer behavior. In addition to his scientific work, Dr. Saad is a leading public intellectual who often writes and speaks about idea pathogens that are destroying logic, science, reason, and common sense. _______________________________________
Holmberg's Morning Sickness - Brady Report - Wednesday February 1, 2023
Is war in long-term decline? Steven Pinker's The Better Angels of Our Nature brought this previously obscure academic question to the centre of public debate, and pointed to rates of death in war to argue energetically that war is on the way out. But that idea divides war scholars and statisticians, and so Better Angels has prompted a spirited debate, with datasets and statistical analyses exchanged back and forth year after year. The lack of consensus has left a somewhat bewildered public (including host Rob Wiblin) unsure quite what to believe. Today's guest, professor in political science Bear Braumoeller, is one of the scholars who believes we lack convincing evidence that warlikeness is in long-term decline. He collected the analysis that led him to that conclusion in his 2019 book, Only the Dead: The Persistence of War in the Modern Age. Links to learn more, summary and full transcript. The question is of great practical importance. The US and PRC are entering a period of renewed great power competition, with Taiwan as a potential trigger for war, and Russia is once more invading and attempting to annex the territory of its neighbours. If war has been going out of fashion since the start of the Enlightenment, we might console ourselves that however nerve-wracking these present circumstances may feel, modern culture will throw up powerful barriers to another world war. But if we're as war-prone as we ever have been, one need only inspect the record of the 20th century to recoil in horror at what might await us in the 21st. Bear argues that the second reaction is the appropriate one. The world has gone up in flames many times through history, with roughly 0.5% of the population dying in the Napoleonic Wars, 1% in World War I, 3% in World War II, and perhaps 10% during the Mongol conquests. And with no reason to think similar catastrophes are any less likely today, complacency could lead us to sleepwalk into disaster. He gets to this conclusion primarily by analysing the datasets of the decades-old Correlates of War project, which aspires to track all interstate conflicts and battlefield deaths since 1815. In Only the Dead, he chops up and inspects this data dozens of different ways, to test if there are any shifts over time which seem larger than what could be explained by chance variation alone. In a nutshell, Bear simply finds no general trend in either direction from 1815 through today. It seems like, as philosopher George Santayana lamented in 1922, "only the dead have seen the end of war". In today's conversation, Bear and Rob discuss all of the above in more detail than even a usual 80,000 Hours podcast episode, as well as: • Why haven't modern ideas about the immorality of violence led to the decline of war, when it's such a natural thing to expect? • What would Bear's critics say in response to all this? • What do the optimists get right? • How does one do proper statistical tests for events that are clumped together, like war deaths? • Why are deaths in war so concentrated in a handful of the most extreme events? • Did the ideas of the Enlightenment promote nonviolence, on balance? • Were early states more or less violent than groups of hunter-gatherers? • If Bear is right, what can be done? • How did the 'Concert of Europe' or 'Bismarckian system' maintain peace in the 19th century? • Which wars are remarkable but largely unknown? Get this episode by subscribing to our podcast on the world's most pressing problems and how to solve them: type 80,000 Hours into your podcasting app. Producer: Keiran Harris Audio mastering: Ryan Kessler Transcriptions: Katy Moore