Podcasts about residues

This interview was recorded for the GOTO Book Club.http://gotopia.tech/bookclubRead the full transcription of the interview hereBarry O'Reilly - Founder at Black Tulip Tech and Author of "Residues" & "The Architect's Paradox"Jacqui Read - Software Architect, Speaker & Author of "Communication Patterns"RESOURCESBarryhttps://bsky.app/profile/technologytulip.bsky.socialhttps://www.linkedin.com/in/barry-o-reilly-b924657https://www.blacktulip.seJacquihttps://bsky.app/profile/tekiegirl.bsky.socialhttps://jacquiread.comhttps://fosstodon.org/@tekiegirlhttps://www.linkedin.com/in/jacquelinereadhttps://github.com/tekiegirlDESCRIPTIONIn this GOTO Book Club interview, Jacqui Read discusses with Barry O'Reilly his books "Residues: Time, Uncertainty, and Change in Software Architecture" and "The Architect's Paradox". He explains how uncertainty defines the architect's role and introduces residuality—a method where architects deliberately stress their conceptual models until they collapse, then optimize the resulting "residues" or leftovers to create more resilient systems.Unlike traditional software engineering approaches, that try to eliminate uncertainty through rigid requirements, residuality embraces random stressors (even far-fetched scenarios like giant lizards) to uncover architectural fault lines.O'Reilly argues that this playful yet mathematically sound approach produces more robust architectures than conventional methods, and his second book explores how inherited philosophical thinking often undermines software architecture's effectiveness in complex business contexts.RECOMMENDED BOOKSBarry O'Reilly • ResiduesBarry O'Reilly • The Architect's ParadoxJacqui Read • Communication PatternsAnne Currie & Jamie Dobson • The Cloud Native AttitudeGregor Hohpe • The Software Architect ElevatorGregor Hohpe • Enterprise Integration Patterns, Vol 2BlueskyTwitterInstagramLinkedInFacebookCHANNEL MEMBERSHIP BONUSJoin this channel to get early access to videos & other perks:https://www.youtube.com/channel/UCs_tLP3AiwYKwdUHpltJPuA/joinLooking for a unique learning experience?Attend the next GOTO conference near you! Get your ticket: gotopia.techSUBSCRIBE TO OUR YOUTUBE CHANNEL - new videos posted daily!

What percentage of meat samples test positive for drug residue violations?

Technological University Dublin (TU Dublin) and BioAtlantis have announced the launch of an innovative new research initiative, VASEACAD (Valorising Seafood Side Streams, Residues, Unwanted Catches and Discards). The project is funded under the EU-SBEP-2 Call (Second Sustainable Blue Economy Partnership) and is supported by the Marine Institute. With a total funding award of €1.6 million, including €299,525 granted to TU Dublin, the VASEACAD project brings together a consortium of 10 partners from across the EU. The project aims to transform fish processing by-products (materials that are typically discarded), into bioactive protein hydrolysates and other high value biomolecules through state-of-the-art bioprocessing techniques. The goal is to create functional and sustainable ingredients for commercial use, supporting a circular and resource-efficient bioeconomy. Leading the research at TU Dublin is Dr Azza Silotry Naik, Principal Investigator, lecturer and expert in food biotechnology and marine byproduct valorisation who stated: 'This project represents an exciting opportunity to develop sustainable solutions for marine by-products by leveraging bioprocessing to create ingredients with functional and commercial potential. I'm proud to collaborate with BioAtlantis and grateful to the Marine Institute for recognising the importance of this work in supporting both sustainability and innovation' Dr Naik brings substantial expertise to the initiative, having previously worked on several EU and nationally funded marine research projects, and led the development of functional ingredients in both academic and commercial R&D environments. Headquartered in County Kerry, BioAtlantis is a pioneering biotech company specialising in bioactives derived from marine and terrestrial sources. It is home to the largest seaweed extraction facility in Ireland and Britian and has a long track record of collaborating with academic institutions. Discussing the partnership, John T. O'Sullivan, CEO of BioAtlantis said: 'BioAtlantis is delighted to partner with Technological University Dublin in the VASEACAD project, focusing on converting fish by-products into valuable ingredients utilising bioprocessing techniques for different market segments. This project not only supports the circular blue bioeconomy, but also aligns with our commitment to developing sustainable, science-based solutions'. The Marine Institute, Ireland's national agency for marine research and innovation, welcomed the project's alignment with national priorities for sustainability and resource efficiency. Veronica Cunningham, Research Funding Office Manager; Marine Institute commented: 'We are pleased to support the VASEACAD project under the EU Sustainable Blue Economy Partnership. Valorisation of marine side streams is critical to reducing waste, supporting innovation, and strengthening Ireland's marine bioeconomy. Projects like this demonstrate the strength of collaborative research in delivering solutions that benefit the environment and provide opportunities for industry too.' The project is also receiving strategic support from Professor Christine O'Connor, Head of Research and Innovation, Faculty of Sciences and Health at TU Dublin. Prof O'Connor, with her expertise in waste valorisation and chemical analysis, will act as a senior advisor on the project, helping guide its scientific direction and impact. VASEACAD reflects TU Dublin's commitment to research with real-world impact, combining academic expertise, industry collaboration, and sustainability driven innovation to contribute to a more resilient and circular blue economy. The VASEACAD project is carried out with the support of the Marine Institute funded by the Government of Ireland under the Sustainable Blue Economy Partnership co-funded by the European Union, and co-branded by the UN Decade of Ocean Science 2021-2030. More about Irish Tech News Irish Tech News are Ireland's No. 1 Online Tech Publication and ofte...

Fredrik talks to Barry O’Reilly about software architecture. Barry has spent a lot of time and energy connecting software architecture to actual code and development work, and finding good ways of actually training new generations of software architects. Architecture is a level above programming, it is a different skill, and it needs to be properly taught so that more people can think and make active decisions about it. Oh, and architecture happens at a group level. You can’t really do it alone. Barry’s quest led him to complexity science, a PhD to actually prove his ideas hold up, and two books. The idea that you have to understand what goes on in the code in order to do good architecture is more controversial than one might think. Thank you Cloudnet for sponsoring our VPS! Comments, questions or tips? We a re @kodsnack, @tobiashieta, @oferlund and @bjoreman on Twitter, have a page on Facebook and can be emailed at info@kodsnack.se if you want to write longer. We read everything we receive. If you enjoy Kodsnack we would love a review in iTunes! You can also support the podcast by buying us a coffee (or two!) through Ko-fi. Links Barry Black tulip Complexity science IDE Antifragile Nassim Taleb Nassim guesting Econtalk talking about antifragility while the book was in progress Barry’s papers: No More Snake Oil: Architecting Agility through Antifragility (2019) An introduction to residuality theory: Software design heuristics for complex systems (2020) The Machine in the Ghost: Autonomy, Hyperconnectivity, and Residual Causality (2021) The Philosophy of Residuality Theory (2021) Residuality Theory, random simulation, and attractor networks (2022) Residuality and Representation: Toward a Coherent Philosophy of Software Architecture (2023) Domain driven design Europe Leanpub Residues - Barry’s first book Barry’s NDC talks - on process and on philosophy Support us on Ko-fi Our agile release train engineer stickers The architect’s paradox - Barry’s second book Accelerate Øredev Kodsnack 346 - Tomer Gabel about the golden age of tomfoolery Dataföreningen Dataföreningen kompetens Titles How we design and think about structure Climbed the greasy pole Keep close to the code Remove themselves from the code as a status symbol I would see a lot of grey There’s a generation missing A level of thinking above programming When you look up from your IDE We had to rescue architecture When they say “architect” Headed for that ivory tower A self-titling profession Comfortable in uncertainty Multiple books, and a PhD How does this thing break Everything will always break Patching those cracks Do you have any proof of this? The key to good software architecture is pessimism The mincing of academic criticism Typing furiously Hope for the future He’s from the real world!

AABP Executive Director Dr. Fred Gingrich is joined by AABP Past President Dr. Pat Gorden, a professor of dairy production medicine and clinical pharmacology at Iowa State University College of Veterinary Medicine. We review the meaning of violative drug residues and the most common medications used in cattle that have historically been associated with violative drug residues. Gorden also reviews both how animals are selected for testing and how withdrawal intervals are determined by drug sponsors when going through the drug approval process. Of particular importance is the effect of disease on the clearance of drugs from the animal since the residue studies are performed on healthy animals for FDA submission. Gorden reviews basic pharmacologic mechanisms for drugs and how disease state may impact drug clearance. He also reviews a study he performed that looked at severe clinical mastitis cows and the impact on the pharmacokinetics of ceftiofur in these animals. Veterinarians should utilize FARAD for withdrawal determinations and consider disease state on drug clearance.  Finally, Gorden offers suggestions for practicing veterinarians to review with farm managers and employees, including observations in the hospital pen or when treatments are administered. Ensuring correct protocol compliance, applying correct therapy, estimating the correct weight, extending the withdrawal interval on sick animals, ensuring the correct dose, route and volume of injection, and fully mixing suspensions prior to filling the syringe are all important items to check. Veterinarians are tasked with ensuring appropriate oversight on drug use on farms and regularly reviewing these steps is an important aspect of this stewardship principle as well as creating billable hours that are valued by the client. P.J. Gorden, M.D. Kleinhenz, L.W. Wulf, B. KuKanich, C.J. Lee, C. Wang, J.F. Coetzee, Altered plasma pharmacokinetics of ceftiofur hydrochloride in cows affected with severe clinical mastitis, J Dairy Sci. Volume 99, Issue 1, 2016, Pages 505-514, https://doi.org/10.3168/jds.2015-10239. Gorden PJ, Ydstie JA, Kleinhenz MD, et al. Comparative plasma and interstitial fluid pharmacokinetics and tissue residues of ceftiofur crystalline-free acid in cattle with induced coliform mastitis. J Vet Pharmacol Therap. 2018; 41: 848–860. https://doi.org/10.1111/jvp.12688.  

The topic of this podcast episode is the liver and its importance for bodily function. Nurse Doza emphasizes how common it is for people to have a fatty liver due to their diet, specifically fast food consumption. He explains how the sugar and fructose in these foods directly affect the liver and contribute to non-alcoholic fatty liver disease. He also encourages listeners to take control of their diet and make choices that support a healthy liver. This episode provides practical tips for improving liver health and acknowledges the positive impact the podcast is having on listeners' lives.   TIMESTAMPS: 00:00 START 06:20 The liver and its importance. 09:07 Non-alcoholic fatty liver disease. 12:09 Importance of food and nutrients. 15:44 Alcohol's contribution to diabetes. 21:46 Liver-supporting supplements. 23:05 Resveratrol in the Mediterranean diet. 29:38 Liver health and supplements. 32:45 Gut and liver relationship. 34:07 Fasting for a healthier liver. 37:22 Liver health practices. Introducing Liver Love: Every vibrant life begins with a healthy core. Cleanse, rejuvenate, and love your liver with our premium supplement, "Liver Love". Designed meticulously for Phase 1 and 2 of liver detoxing. Begin your journey to a healthier you. Click here to get Liver Love now! Show Notes:   The Importance of Supporting Antioxidant Production.[^1^] - The crux of health issues: Inflammation. - The origin of inflammation: Stress. - Consequences of chronic stress: Bodily dysfunction. - The liver: A powerhouse of antioxidant production[^2^]. - Glutathione: Liver's potent gift and its profound benefits[^3^]. - Introducing NAC: Glutathione's precursor and its significance[^4^]. - The need for NAC and glutathione supplementation. - The liver-enhancing power of B vitamins[^5^].   Hormone Regulation & The Liver[^6^] - The liver's pivotal role in hormone regulation. - The communicative power of hormones. - Liver: The body's natural storage facility. - Better hormones equate to a healthier liver[^7^]. - Early menopause's potential link to liver health[^8^]. - The underappreciated link: Liver and insulin. - The domino effect: Insulin issues leading to hormonal imbalances[^9^].   The Perils of Fast Food on Liver Health[^10^] - The challenges in processing fast food. - Residues of past unhealthy diets lingering in the liver. - Beyond fast food: The toll of an unhealthy diet on the liver[^11^]. - The equation of good fats and a healthier liver. - Avocado: The liver's best friend. - Monounsaturated fat: A top-tier dietary inclusion[^12^]. - The liver's role in cholesterol production[^13^]. - The promise of fish oil for liver wellness[^14^]. - The connection: Fatty liver, omega 3, and choline deficiencies[^15^].   Decoding the Relationship: Liver & Estrogen[^16^] - Fatty liver's association with compromised estrogen. - Estrogen production's direct tie to the liver[^17^]. - The toll of birth control on liver health and estrogen quality[^18^]. - The malleability of epigenetics[^19^]. - Stress, liver health, and its implications on estrogen[^20^]. - The genetic connection to liver health and detoxification needs[^21^]. - Delving into the COMT gene's role in hormone regulation[^22^]. - The intersection of cholesterol, liver, and menopause-associated estrogen[^23^].   Methylation & Its Influence on Liver Function[^24^] - The expression of the MTHFR gene in the liver. - Prevalence and implications of MTHFR gene mutation[^25^]. - The methylation cycle's role in vitamin metabolism[^26^]. - Significance of B9 in methylation and liver functions[^27^]. - The interconnected web: MTHFR gene's impact on various bodily processes[^28^]. - Glutathione production's link to correct methylation[^29^]. - Methylation's role in disease risk[^30^]. - The importance of methylated vitamins for MTHFR gene support[^31^]. - The intertwined roles of MTHFR and COMT genes in methylation[^32^]. Discover Liver Love: Let's face it, our livers undergo a lot, daily. Toxins, processed foods, medications, and more. It's time to give back. Show your liver some love with our specially formulated detox supplement, "Liver Love". The first step towards a healthier tomorrow starts with a cleanse today. Tap here to give your liver the love it deserves!   ---   **REFERENCES**:   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320789/figure/molecules-23-03305-f001/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/#B4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125908/ https://pubmed.ncbi.nlm.nih.gov/14973104/ https://pubmed.ncbi.nlm.nih.gov/19095062/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726297/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/ https://pubmed.ncbi.nlm.nih.gov/334126/ https://www.ahajournals.org/doi/10.1161/JAHA.120.020560 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228367/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123374/#MOESM3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674329/#R28 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531579/#B30

Plus Manufacturing, Inc.'s Procyon Soap Free Multi-Purpose Cleaner & Degreaser offers superior cleaning results with no sticky soapy residues. Check it out at https://soapfreeprocyon.com/shop Plus Manufacturing, Inc. City: Spokane Address: 2704 N Madelia St Website: https://soapfreeprocyon.com/ Phone: +18007762966 Email: press@soapfree.net

Terry McElvaney, Veterinary Inspector at the Veterinary Medicines, Antimicrobial Resistance, Byproducts and TSE Division, joins Stuart Childs on this week's Dairy Edge podcast to discuss residues in milk. Terry first explains the role of the division in which he works and how it is important in facilitating trade. Terry says that the division tests 15,000 samples annually and carries out 70,000 tests on these samples for many different types of residues in order to report to the EU on our compliance with the regulations around the use of veterinary products in animals that go into the food chain. He says that while a miniscule percentage of samples test positive each year, this year there has been an increase in the positives associated with Ivermectin and Levamisole, active ingredients in wormers and flukicides. Terry advises farmers to test before treating and to ensure the right product is used at the right rate at the right time.  Observing withdrawals is important and people need to carefully record dates of administration to ensure those withdrawals are observed. Terry also warns people that stock will often calve ahead of time and when that does happen, the withdrawal period still needs to be observed. He finishes by recommending people avoid unnecessary use of any veterinary medicinal products when possible and where they have to be used, to get good advice on the product to use.    For more episodes from the Dairy Edge podcast go to the show page at: https://www.teagasc.ie/animals/dairy/the-dairy-edge-podcast/ The Dairy Edge is a co-production with LastCastMedia.com

For this week's OviCast, we're joined by Terry McElvaney, Veterinary Inspector with Department of Agriculture, Food and the Marine, to discuss some issues that have occurred with flukicide residues in lamb carcasses.  We discuss the problems encountered and the follow up investigations with Terry explaining some of the issues caused and issues they have encountered.  We also discuss the key areas to focus on when using anthelminthic and antibiotics to avoid these type of issues occurring.   Details of licensed veterinary products can be found on the HPRA veterinary medicines webpage: https://www.hpra.ie/homepage/veterinary/veterinary-medicines-information For more episodes from the OviCast podcast, visit the show page at:https://www.teagasc.ie/animals/sheep/ovicast-sheep-podcast

Today we look at some of the colonial legacies in discourses around girls' education. With me are Chris Kirchgasler and Karishma Desai. They've recently published an article entitled, “'Girl' in Crisis: Colonial Residues of Domesticity in Transnational School Reforms,” which was published in the Comparative Education Review. Chris Kirchgasler is an Assistant Professor at the University of Wisconsin-Madison and Karishma Desai is an assistant Professor at Rutgers Graduate School of Education. freshedpodcast.com/kirchgasler-desai/ -- Get in touch! Twitter: @FreshEdpodcast Facebook: FreshEd Email: info@freshedpodcast.com

(Dhamma Stream Online Sessions)

(Dhamma Stream Online Sessions)

The USDA published the 2022 Pesticide Data Program Annual Summary that shows over 99% of tested samples had pesticide residues BELOW EPA benchmark levels, and House lawmakers launched a new Agricultural Trade Caucus, seeking to advance and promote policies vital to U.S. agriculture.

The USDA published the 2022 Pesticide Data Program Annual Summary that shows over 99% of tested samples had pesticide residues BELOW EPA benchmark levels, and House lawmakers launched a new Agricultural Trade Caucus, seeking to advance and promote policies vital to U.S. agriculture.

Join us as we unravel a critical consumer concern—the presence of antibiotic residues in our food. Delve into the potential health risks and the serious illnesses they might lead to. By the end of this podcast, you'll acquire a thorough understanding of the dangers posed by antibiotic residues and discover effective ways to minimize their adverse effects.Please visit https://healthfactsdiva.com for resources.Support the showPlease be advised that the following program is for entertainment purposes only. Consult your doctor for medical advice.

Join us as we unravel a critical consumer concern—the presence of antibiotic residues in our food. Delve into the potential health risks and the serious illnesses they might lead to. By the end of this podcast, you'll acquire a thorough understanding of the dangers posed by antibiotic residues and discover effective ways to minimize their adverse effects.Please visit https://healthfactsdiva.com for resources.Support the showPlease be advised that the following program is for entertainment purposes only. Consult your doctor for medical advice.

Impressions stay in your memory. For example, if I have watched a film in the evening, individual sequences or images from the film keep coming back to me the next day, even though I may have only watched it to switch off and not really consciously or with much intention. I sometimes notice the same thing with things I've heard or when I cycle past an advert. Much of what our senses perceive is left behind. Or as the Latin proverb aptly puts it: semper aliquid haeret - something always sticks. This makes it all the more important to consciously pay attention to what we impose and inflict on our senses. We do this more or less carefully and consciously when it comes to food. How is it with you? Do you have a healthy approach to consuming information or would it perhaps be time for a diet for your eyes or ears? I wish you an extraordinary day!

Welcome back to another Q and A episode of the Nutrition Science Podcast. We have some exciting topics today, we will be discussing:  Whether air fryers are safe or not How to remove pesticide residues from food If colostrum has any benefits  Whether I think misinformation should be illegal  And the health effects of deli meats  Tune in to the show to hear more. Links  Take Advantage of Limited Time Discounted Course Offer Legion Supplements BOGO Sale (Use code Chavez at checkout)  Paper on removing pesticide residues in food ----> https://pubmed.ncbi.nlm.nih.gov/29222908/ Research on colostrum ---> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255475/  

We will address a crucial issue that impacts us as consumers. We will delve into the subject of antibiotic residues in the food we eat, which can be harmful to our health and potentially lead to serious illnesses, such as cancer. By the end of this podcast, you will gain a comprehensive understanding of the risks associated with antibiotic residues and learn ways to minimize their adverse effects.Support the showPlease be advised that the following program is for entertainment purposes only. Consult your doctor for medical advice.

The topic of this podcast episode is the liver and its importance for bodily function. Nurse Doza emphasizes how common it is for people to have a fatty liver due to their diet, specifically fast food consumption. He explains how the sugar and fructose in these foods directly affect the liver and contribute to non-alcoholic fatty liver disease. He also encourages listeners to take control of their diet and make choices that support a healthy liver. This episode provides practical tips for improving liver health and acknowledges the positive impact the podcast is having on listeners' lives.   TIMESTAMPS: 00:00 START 06:20 The liver and its importance. 09:07 Non-alcoholic fatty liver disease. 12:09 Importance of food and nutrients. 15:44 Alcohol's contribution to diabetes. 21:46 Liver-supporting supplements. 23:05 Resveratrol in the Mediterranean diet. 29:38 Liver health and supplements. 32:45 Gut and liver relationship. 34:07 Fasting for a healthier liver. 37:22 Liver health practices. Introducing Liver Love: Every vibrant life begins with a healthy core. Cleanse, rejuvenate, and love your liver with our premium supplement, "Liver Love". Designed meticulously for Phase 1 and 2 of liver detoxing. Begin your journey to a healthier you. Click here to get Liver Love now! Show Notes:   The Importance of Supporting Antioxidant Production.[^1^] - The crux of health issues: Inflammation. - The origin of inflammation: Stress. - Consequences of chronic stress: Bodily dysfunction. - The liver: A powerhouse of antioxidant production[^2^]. - Glutathione: Liver's potent gift and its profound benefits[^3^]. - Introducing NAC: Glutathione's precursor and its significance[^4^]. - The need for NAC and glutathione supplementation. - The liver-enhancing power of B vitamins[^5^].   Hormone Regulation & The Liver[^6^] - The liver's pivotal role in hormone regulation. - The communicative power of hormones. - Liver: The body's natural storage facility. - Better hormones equate to a healthier liver[^7^]. - Early menopause's potential link to liver health[^8^]. - The underappreciated link: Liver and insulin. - The domino effect: Insulin issues leading to hormonal imbalances[^9^].   The Perils of Fast Food on Liver Health[^10^] - The challenges in processing fast food. - Residues of past unhealthy diets lingering in the liver. - Beyond fast food: The toll of an unhealthy diet on the liver[^11^]. - The equation of good fats and a healthier liver. - Avocado: The liver's best friend. - Monounsaturated fat: A top-tier dietary inclusion[^12^]. - The liver's role in cholesterol production[^13^]. - The promise of fish oil for liver wellness[^14^]. - The connection: Fatty liver, omega 3, and choline deficiencies[^15^].   Decoding the Relationship: Liver & Estrogen[^16^] - Fatty liver's association with compromised estrogen. - Estrogen production's direct tie to the liver[^17^]. - The toll of birth control on liver health and estrogen quality[^18^]. - The malleability of epigenetics[^19^]. - Stress, liver health, and its implications on estrogen[^20^]. - The genetic connection to liver health and detoxification needs[^21^]. - Delving into the COMT gene's role in hormone regulation[^22^]. - The intersection of cholesterol, liver, and menopause-associated estrogen[^23^].   Methylation & Its Influence on Liver Function[^24^] - The expression of the MTHFR gene in the liver. - Prevalence and implications of MTHFR gene mutation[^25^]. - The methylation cycle's role in vitamin metabolism[^26^]. - Significance of B9 in methylation and liver functions[^27^]. - The interconnected web: MTHFR gene's impact on various bodily processes[^28^]. - Glutathione production's link to correct methylation[^29^]. - Methylation's role in disease risk[^30^]. - The importance of methylated vitamins for MTHFR gene support[^31^]. - The intertwined roles of MTHFR and COMT genes in methylation[^32^]. Discover Liver Love: Let's face it, our livers undergo a lot, daily. Toxins, processed foods, medications, and more. It's time to give back. Show your liver some love with our specially formulated detox supplement, "Liver Love". The first step towards a healthier tomorrow starts with a cleanse today. Tap here to give your liver the love it deserves!   ---   **REFERENCES**:   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320789/figure/molecules-23-03305-f001/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/#B4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125908/ https://pubmed.ncbi.nlm.nih.gov/14973104/ https://pubmed.ncbi.nlm.nih.gov/19095062/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726297/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/ https://pubmed.ncbi.nlm.nih.gov/334126/ https://www.ahajournals.org/doi/10.1161/JAHA.120.020560 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228367/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123374/#MOESM3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674329/#R28 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531579/#B30

Demos These are: Quadratic residues: https://asecuritysite.com/primes/q_res Jacobi symbol: https://asecuritysite.com/primes/jac Jacobi and Legendre symbol: https://asecuritysite.com/primes/jacobi Introduction Remember at school that class where the teacher taught you about how to square something? It was great, and where we loved to take the square of 3 and get 9, and the square of 5 gave us 25. But, in the next lesson, we came back to earth with a bump, as it was time for the nasty little square root. Now, we have to find two numbers which when multiplied together, gave us 121, or 196. Luckily, there was a convenient button on the calculator that give us our quick answer. In the time before calculators, though, working out more complex square roots involved tables of logarithms. And, so, in this podcast, I will outline a difficult problem … find a square root in a modulo n world … aka quadratic residues. A hard problem In cryptography, we look for hard problems to solve. For this, we can create a backdoor into the problem and solve the problem. With discrete logarithms, we have a hard problem of: Y=g^x (mod p) and where it is difficult to determine x, even though we know g, Y and p, but as long as the prime number if large enough. Another hard problem is used in the RSA public key method, and this involves the difficulty in factorization at modulus (N) which is made up of two prime numbers.  Another hard problem is quadratic residues modulus n, and uses the form of: x²=a (mod p) and where we must find a value of x which results in a value of a (mod p). If a solution exists, the value of a is a quadratic residue (mod n).  In modular arithmetic, this operation is equivalent to a square root of a number (and where x is the modular square root of a modulo p). In the following, we will try and solve for the value of x, and also generate the Legendre symbol value. For example, if we have a=969 and p=1223, we get: Solve x²=968 (mod 1223) [Ans: 453] Try! and: Solve x²=1203 (mod 1223) [Ans: 375] Try! Thus 968 and 1203 are quadratic residues modulo 1223. The form of x²=a (mod p) is not always solvable. For example, if we have a=209 and p=1223 , we get: x²=209 (mod 1223) Also, if a shares a factor with p it is also not solvable. For example: x²=39 (mod 13) will return a zero value for x. If we take a value of p=53, we get the following values [here]: 0, 1, 4, 6, 7, 9, 10, 11, 13, 15, 16, 17, 24, 25, 28, 29, 36, 37, 38, 40, 42, 43, 44, 46, 47, 49, 52 A sample run of the code gives: Quadradic residue (mod n) solver a: 47 p: 53We need to solve for: val^2 = 47 (mod 53 )-----------------------Result: 10( 10 )^2 = 47 (mod 53 )-----------------------For a prime number of 53 here are the residues up to p (or 100)1 4 6 7 9 10 11 13 15 16 17 24 25 28 29 36 37 38 40 42 43 44 46 47 49 52 In this case, we see that 10 is a possible quadratic residue for a p of 53. The solution is thus: 10²=47(mod 53) You can see a demonstration here and here are some examples: Solve x²=12 (mod 13) [Ans: 8] Try! Solve x²=968 (mod 1223) [Ans: 453] Try! Solve x²=1203 (mod 1223) [Ans: 375] Try! Solve x²=47 (mod 53) [Ans: 10] Try! Solve x²=209 (mod 1223) [No solution!] Try! Solve x²=888 (mod 1223) [No solution!] Try! Solve x²=39 (mod 13) [No solution!] Try! Legendre symbol In science, it is difficult to avoid Adrien-Marie Legendre, as there are so many things named after him: Fourier–Legendre series; Gauss–Legendre algorithm; Legendre chi function; Legendre duplication formula; Legendre–Papoulis filter; Legendre form; Legendre polynomials; Legendre sieve; Legendre symbol; Legendre transformation; Legendre wavelet; Legendre–Clebsch condition; Legendre–Fenchel transformation; Legendre's constant; Legendrian knot; and Gamma function–Legendre formula. And, so, where does Legedre help with your online security? Well, you will find his method used in elliptic curve methods, which are used to protect your online identity, and the security of the communications that you have with this Web page. So, let's look at the Legendre Symbol. For this, we turn to Legendre who, in 1798, defined the Legendre symbol. In the following, we will try and solve for the value of x, and also generate the Legendre symbol value [link]: Solve x²=12 (mod 13) With his method, we can determine that the answer is 8, as 64 (mod 13) is 12. Some sample code is [here]: import sysimport libnumdef legendre_symbol(a, p): ls = pow(a, (p - 1) // 2, p) return -1 if ls == p - 1 else lsn=11if (len(sys.argv)>1): n=int(sys.argv[1])print ("Here are the Z*p (quadratic residues modulo n and coprime to n):")print ("nJacobi symbol")for a in range(1, n): rtn= libnum.jacobi(a,n) if (rtn==1): print (a,end=', ')print ("nLegendre symbol")for a in range(1, n): rtn= legendre_symbol(a,n) if (rtn==1): print (a,end=', ') A quadratic residue relates to the solving of the form: y=x² (mod n), and where we need to find values of y for different values of x and for a given modulus (n). For n=11, we get Z∗p={1, 3, 4, 5, 9}. This is because, 1² (mod11)=1, 2² (mod11)=4, 3² (mod11)=9, 4² (mod11)=5, 5² (mod11)=3, 6² (mod11)=3, 7² (mod11)=5, 8² (mod11)=9, 9² (mod11)=4, and 10² (mod11)=1. To find the quadratic residues for a given modulus, we can use the Jacobi symbol is: and is defined as: The legendre_symbol returns: 1. When a is a quadratic residue of p. -1. When a is a quadratic nonresidue of p. 0. When a shares a factor of p. The Jacobi symbol was defined by Carl Gustav Jacob Jacobi as a generalized form of the Legendre symbol. Elliptic Curves While we have a trivial example here, we can use it for more complex ones, such as finding a point on the elliptic curve [here]. A sample run is: Elliptic curve is: P-192Finding elliptic point closest to: 1Prime number: 6277101735386680763835789423207666416083908700390324961279a,b -3 2455155546008943817740293915197451784769108058161191238065(2, 1126956676167578795924565825825899020268914906345645360775L)(3, 2476168101441297080746512578325117519920374855425678540834L)(5, 936760824408609109609580731987662341845728162027345586443L)(6, 61374494507529673497365598443020935064779457192199494327L)(8, 1539168359597512271047259505090133446672063593980132990812L)(12, 3464753203279792192409824182683870253677262339932562461307L)(13, 3288234558942609973454802567986887155175778959720199156770L)(15, 4548834217212027584647316131131523554591911664904227806291L)(17, 2148916484007672061843886225501299518817815267521173400039L)(18, 1600977792967480259538850281480651298625682822208237361467L)(22, 1682016893107185458056834822961338463540516386180178478778L) The code for this is [here]: import mathimport sysimport libnumdef legendre_symbol(a, p): ls = pow(a, (p - 1) // 2, p) return -1 if ls == p - 1 else lsdef findit(start,p,a,b): x=start count=0 while True: val=((x*x*x) + a*x+ b) % p rtn= legendre_symbol(val, p) if (rtn==1): if (libnum.has_sqrtmod(val,{p: 1})): res=next(libnum.sqrtmod(val,{p: 1})) print(x,int(res)) count=count+1 x=x+1 if (count>20): return if (x-start>200): returnp = 2**256 - 2**224 + 2**192 + 2**96 - 1 a=-3b=41058363725152142129326129780047268409114441015993725554835256314039467401291startval=1type="P-192"if (len(sys.argv)>1): startval=int(sys.argv[1])if (len(sys.argv)>2): type=str(sys.argv[2])if (type=="P-192"): p = 2**192-2**64-1 a=-3 b=2455155546008943817740293915197451784769108058161191238065if (type=="P-224"): b=18958286285566608000408668544493926415504680968679321075787234672564 p = 2**224 - 2**96 + 1 a=-3if (type=="P-256"): p = 2**256 - 2**224 + 2**192 + 2**96 - 1 a=-3 b=41058363725152142129326129780047268409114441015993725554835256314039467401291if (type=="P-384"): a=-3 b=27580193559959705877849011840389048093056905856361568521428707301988689241309860865136260764883745107765439761230575 p = 2**384 - 2**128 - 2**96 + 2**32 - 1 if (type=="Curve25519"): a=486662 b=1 p = 2**255 - 19 if (type=="secp256k1"): a=0 b=7 p = 2**256 - 2**32 - 977 if (type=="M-221"): a=117050 b=1 p = 2**221 - 3 if (type=="BN(2,254)"): a=0 b=2 p = 16798108731015832284940804142231733909889187121439069848933715426072753864723 if (type=="M-383"): a=2065150 b=1 p = 2**383 - 187 print("Elliptic curve is:tt",type)print("Finding elliptic point closest to:t",startval)print("Prime number:ttt",p)print("a,b",a,b)findit(startval,p,a,b)

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.04.547731v1?rss=1 Authors: Tennakoon, M., Thotamune, W., Payton, J. L., Karunarathne, A. Abstract: Prenylation is a universal and irreversible post-translational modification that supports membrane interactions of proteins involved in various cellular processes, including migration, proliferation, and survival. Thus, dysregulation of prenylation contributes to multiple disorders, including cancers, vascular diseases, and neurodegenerative diseases. During prenylation, prenyltransferase enzymes tether metabolically produced isoprenoid lipids to proteins via a thioether linkage. Pharmacological inhibition of the lipid synthesis pathway by statins has long been a therapeutic approach to control hyperlipidemia. Building on our previous finding that statins inhibit membrane association of G protein {gamma} (G{gamma}) in a subtype-dependent manner, we investigated the molecular reasoning for this differential. We examined the prenylation efficacy of carboxy terminus (Ct) mutated G{gamma} in cells exposed to Fluvastatin and prenyl transferase inhibitors and monitored the subcellular localization of fluorescently tagged G{gamma} subunits and their mutants using live-cell confocal imaging. Reversible optogenetic unmasking-masking of Ct residues was used to probe their contribution to the prenylation process and membrane interactions of the prenylated proteins. Our findings suggest that specific Ct residues regulate membrane interactions of the G{gamma} polypeptide statin sensitivity and prenylation efficacy. Our results also show that a few hydrophobic and charged residues at the Ct are crucial determinants of a protein's prenylation ability, especially under suboptimal conditions. Given the cell and tissue-specific expression of different G{gamma} subtypes, our findings explain how and why statins differentially perturb heterotrimeric G protein signaling in specific cells and tissues. Our results may provide molecular reasoning for repurposing statins as Ras oncogene inhibitors and the failure of using prenyltransferase inhibitors in cancer treatment. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

https://paranormalhub.com/grizzly-hunt This Wednesday at 4:00 PM EST Time! Grizzly On The Hunt and FDL Paranormal discusses haunted items including dolls. Grizzly has so much activity in his studio around his dolls it's incredible. Activity being caught on live shows in progress. Grizzly also has poltergeist activity during a show us as well. Grizzly uses lighted up cat balls, Rim Pod and other ghost investigator equipment to document his activity that has continuously to ramp up activity that is present and documenting these occurrences. Due to the poltergeist activity in his studio Grizzly has to secure items down with type so devices will not be toss or thrown during live shows. Grizzly has reached out to several psychics mediums that are well known and confirmed that many of Grizzly's dolls have attachments! Haunted objects are inanimate items that are believed to possess supernatural or paranormal properties. These objects are said to be imbued with the presence of spirits or energies that can influence their surroundings or interact with people. Haunted objects can come in various forms, including jewelry, furniture, dolls, paintings, and even everyday items. These objects are often associated with stories of strange occurrences, unexplained phenomena, and negative or unsettling experiences reported by those who have come inte contact with them. One famous example of a haunted object is the Annabelle doll, which gained notoriety through the "Conjuring" film franchise. The real Annabelle doll, a Raggedy Ann doll, is kept in a glass case at the Warrens' Occult Museum in Connecticut. It is said to be possessed by a malevolent spirit and has been associated with a range of paranormal incidents. Another well-known haunted object is the Hope Diamond, a large blue diamond that is rumored to bring misfortune and tragedy to its owners. Legend has it that anyone who possesses the diamond will suffer from bad luck and experience various hardships. While the existence and nature of haunted objects are subjects of debate and skepticism, stories and accounts of their paranormal attributes continue to captivate the imagination of many people. The term "haunted attachments" can refer to various things depending on the context. In the paranormal sense, it often refers to objects that are believed to be connected to spirits or entities and can bring about paranormal activity or supernatural experiences It's important to note that beliefs in haunted attachments and their effects vary greatly among individuals, and skepticism is common. Some people find the idea intriguing and believe in the existence of such phenomena, while others view it as purely superstition or imagination. The concept of items being possessed or believed to have supernatural influence can be attributed to various cultural, religious, and paranormal beliefs. Different explanations and beliefs exist across different cultures and belief systems. Here are a few perspectives on why items may be perceived as possessed: #HauntedVessels #ParanormalObjects #GhostlyArtifacts #grizzlychris #EeriePossessions #SupernaturalArt #Curseditems #SpectralAntiques #SpiritInfusedObjects #Spooky Collectibles #EnchantedRelics #PhantomMemorabilia #OtherworldlyArt #SpiritedArtifacts #SupernaturalCollectibles #EtherealPossessions #GhostlyTreasures #HauntedArt #CursedCuriosities #SpectralKeepsakes #ParanormalArtifacts #EerieArtworks #PhantomArt #SupernaturalRelics #GhostlyOddities #EnchantedArt #HauntedMemorabilia @ParanormalObjects @GhostlyArtifacts @EeriePossessions @SupernaturalArt @Curseditems @SpectralAntiques @SpiritinfusedObjects @SpookyCollectibles @EnchantedRelics @PhantomMemorabilia @OtherworldlyArt @SpiritedArtifacts @SupernaturalCollectibles @EtherealPossessions @GhostlyTreasures @HauntedArt @CursedCuriosities @SpectralKeepsakes @ParanormalArtifacts @EerieArtworks @PhantomArt @SupernaturalRelics @GhostlyOddities @EnchantedArt @HauntedMemorabilia --- Send in a voice message: https://podcasters.spotify.com/pod/show/grizzly-onthehunt/message Support this podcast: https://podcasters.spotify.com/pod/show/grizzly-onthehunt/support

Spilled wine? No problem! Plus Manufacturing, Inc.'s soap-free Procyon Spot & Stain Remover will have your carpet looking like new in no time. Shop now at https://soapfreeprocyon.com/shop Plus Manufacturing, Inc. 2704 N Madelia St, Spokane, WA 99207, United States Website https://soapfreeprocyon.com/ Phone +1-800-776-2966 Email press@soapfree.net

Eric Camden (lead investigator with Foresite) and Mike Konrad discuss electrochemical migration (ECM) and other failure modes caused by residues on circuit assemblies.

My guest, Eric Camden (Lead Investigator with Foresite) and I discuss electrochemical migration (ECM) and other failure modes caused by residues on circuit assemblies.Eric Camden's Contact Information:ericc@foresiteinc.comhttps://www.foresiteinc.com

On this edition of Free City Radio we highlight a multimedia project called "Do Right by the Right Whale," which highlights the voice of Mi'kmaq ecological justice activist Brian Issac. Throughout the last summer Brian worked with the Office of Sustainability at Concordia University in Montreal to create this project, of which you can hear the audio narration on this program. Importantly this project speaks to the ways that Mi'kmaq have long held traditional practices through which practices of ecological and environmental sustainability have traveled across generations, a reality that is now important to draw on for building practices today to support and protect the Right Whale. In this episode we hear from Brian Issac who worked with the Office of Sustainability at Concordia. Also we hear from Christian Favreau who shares thoughts about supporting such work through the sustainability office at the university. Music on this edition is "Torn" from the album "Residues" by Jordan Christoff, my brother, out via @amekcollective Free City Radio is hosted and produced by Stefan @spirodon Christoff and airs on @radiockut 90.3FM at 11am on Wednesdays and @cjlo1690 AM in Tiohti:áke/Montréal on Tuesdays at 1pm on @ckuwradio 95.9FM in Winnipeg at 8am on Tuesdays, on @cfrc 101.9FM in Kingston, Ontario at 11:30am on Wednesdays and broadcasting on @cfuv 101.9 FM in Victoria, BC on Wednesdays at 9am. Also Free City Radio is a podcast through both Spotify and Apple Podcasts, please encourage a friend to tune-in !

Agricultural residue or agricultural waste is not waste, it's an asset. Because of biochar it's now valuable! Biochar is a substance that resembles charcoal that is produced from biomass and is sustainably sourced from agricultural and forestry waste. These can be from corn stalks, hulls, wood chips and much more. Check out our blog on “What Materials Has ARTi Successfully Pyrolysed (Turned into biochar)” at the following (Link). But is it really “waste”? Are they only agricultural residues? Firstly, due to the scale of our civilization and the growing human demands, there is more production of everything. This would for sure certainly include agriculturally grown food. More production means more waste, or unneeded materials from the process. That's the nature of production. Did you remember that potato plants have stalks and green leaves? The potato part we eat is just part of the root system in the soil. The stalks and leaves of potato plants for example have little use. Potato plants even generate flowers. Potato flowers, anyone? The global potato industry is enormous, producing 376 million metric tons in 2021. (Potato News Today, Jan. 21st, 2023). This is humongous. So, there's going to be a lot of unwanted biomasses generated.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.04.519021v1?rss=1 Authors: Gil, B., Rose, J., Demurtas, D., Mancini, G.-F., Sordet-Dessimoz, J., Sorrentino, V., Rudinskiy, N., Frosh, M. P., Hyman, B. T., Moniatte, M., Spires-Jones, T. L., Herron, C. E., Schmid, A. W. Abstract: In Alzheimer's disease (AD), Amyloid-beta (A{beta}) oligomers are considered an appealing therapeutic- and diagnostic target. However, to date, the molecular mechanisms associated with the pathological accumulation or structure of A{beta} oligomers remains an enigma to the scientific community. Here we demonstrate the strong seeding properties of unique A{beta} fragment signatures and show that the truncated A{beta}peptides of residues A{beta}1-23, A{beta}1-24 and A{beta}1-25, rapidly seed to form small, SDS-PAGE stable assemblies of ~5kDa to ~14kDa molecular mass range. Mass spectrometry analysis of SDS-PAGE fractionated and gel extracted oligomers revealed that the truncated A{beta} isoforms of residues 1-23 to 1-25 form stable entities with low molecular weight (LMW) oligomers, which strongly resemble the regularly reported A{beta} entities of putative dimeric or trimeric assemblies found in human post-mortem AD and Tg mouse brain extracts. Furthermore, electrophysiological recordings in the mouse hippocampus indicate that LMW A{beta} assemblies formed by fragments A{beta}1-23 to A{beta}1-25 significantly impair long-term-potentiation (LTP) in the absence of full-length A{beta}1-42. Extensive antibody screening highlights the important observation, that the LMW A{beta} assemblies formed by these truncated A{beta} peptides escape immuno-detection using conventional, conformation specific antibodies but, more importantly, the clinical antibody aducanumab. Our novel findings suggest that there are new A{beta} target loopholes which can be exploited for the development of therapeutic antibodies with binding properties against stable target hotspots present in A{beta} oligomers. We provide here a first example of a new class of monoclonal antibody with unique binding properties against LMW A{beta} oligomers, in the absence of binding to large fibrillar A{beta} assemblies, or dense amyloid plaques. Our research supports a novel, unparalleled approach for targeting early, pathological A{beta} species during the insidious phase of AD and prior to the appearance of large oligomeric or protofibrilar assemblies. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.04.515179v1?rss=1 Authors: D'Augustin, O., Gaudon, V., Siberchicot, C., Smith, R., Chapuis, C., DEPAGNE, J., Veaute, X., BUSSO, D., Di-Guilmi, A.-M., Castaing, B., Radicella, J. P., Campalans, A., Huet, S. Abstract: The DNA-glycosylase OGG1 oversees the detection and clearance of the 7,8-dihydro-8-oxoguanine (8-oxoG), which is the most frequent form of oxidized base in the genome. This lesion is deeply buried within the double-helix and its detection requires careful inspection of the bases by OGG1 via a mechanism that remains only partially understood. By analyzing OGG1 dynamics in the nucleus of living human cells, we demonstrate that the glycosylase constantly scans the DNA by rapidly alternating between diffusion within the nucleoplasm and short transits on the DNA. This scanning process, that we find to be tightly regulated by the conserved residue G245, is crucial for the rapid recruitment of OGG1 at oxidative lesions induced by laser micro-irradiation. Furthermore, we show that residues Y203, N149 and N150, while being all involved in early stages of 8-oxoG probing by OGG1 based on previous structural data, differentially regulate the scanning of the DNA and recruitment to oxidative lesions. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Heart-wrenching interview with chemist and 9/11 researcher Kevin Ryan who says additional research needed to pinpoint what's killing tens of thousands of 9/11 emergency responders isn't being funded because no one wants to "go there" and look further at evidence indicating that high-energy thermitic explosions are most likely causing the high death toll among first responders. 

Want an effective rug and upholstery cleaner that has no dangerous chemicals? Plus Manufacturing Inc. (+1-800-776-2966) has you covered! Learn more by visiting https://soapfreeprocyon.com/shop (https://soapfreeprocyon.com/shop)

Join Tim and Kim as they talk about all  your favorite potential residues in beef, from hormones and antibiotics to genetically-modified crops, with Dr. Joe Schwarcz, Director of the Office for Science and Society at McGill University.CitationDoyle, E. (2000). Human Safety of Hormone Implants Used to Promote Growth in Cattle. 24.Hirpessa, B., Ulusoy, B., Hecer, C. (2020). Hormones and Hormonal Anabolics: Residues in Animal Source Food, Potential Public Health Impacts, and Methods of Analysis.  Retrieved August 9, 2022, from https://www.hindawi.com/journals/jfq/2020/5065386/Jeong, S.-H., Kang, D.-J., Lim, M.-W., Kang, C.-S., & Sung, H.-J. (2010). Risk Assessment of Growth Hormones and Antimicrobial Residues in Meat. Toxicological Research, 26(4), 301–313. https://doi.org/10.5487/TR.2010.26.4.301Kumar, S. (2018). Adverse effects on consumer's health caused by hormones administered in cattle. 10.Ramatla, T., Ngoma, L., Adetunji, M., & Mwanza, M. (2017). Evaluation of Antibiotic Residues in Raw Meat Using Different Analytical Methods. Antibiotics, 6(4), 34. https://doi.org/10.3390/antibiotics6040034Smith, Z. K., & Johnson, B. J. (2020). Mechanisms of steroidal implants to improve beef cattle growth: A review. Journal of Applied Animal Research, 48(1), 133–141. https://doi.org/10.1080/09712119.2020.1751642Thieme, D., & Hemmersbach, P. (Eds.). (2010). Doping in Sports (Vol. 195). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-79088-4

Max Tegmark is a cosmologist and renowned physicist. In this interview, we discuss his work on the history ofName-dropping residue purity Cygnus

The harrowing story of the GOOD MADAM, begins with the death of her grandmother, the woman who raised her, Tsidi (Chumisa Cosa) and her daughter are forced to move in with Tsidi's estranged mother, Mavis (Nosipho Mtebe), who has lived and worked in the wealthy suburbs of Cape Town for most of Tsidi's life. Residues of apartheid-era domestic servitude confront legacies of colonial land theft in South African auteur Jenna Cato Bass's daring horror-satire. Jenna Cato Bass (High Fantasy, Flatland) transforms the legacies of South Africa's colonial land theft and Black domestic service to white bosses into a gutsy psychological thriller. Co-written with Babalwa Baartman, Mlungu Wam (Good Madam) grapples with the daily violence that haunts the nation's most pressing political issues, long after the end of apartheid. Summoning horror-satire references from Ousmane Sembène's Black Girl to Jordan Peele's Get Out, Bass and Baartman's suspenseful descent into complex, searing allegory insists on reckoning with the enduring presence of traumas deceptively labelled “history.” Director Jenny Cato Bass and co-screenwriter Babalwa Baartman join us for a conversation on the inspiration for GOOD MADAM, impact and legacy on today's South Africa, their on-going collaboration, and the superb cast of actors who helped them realize their vision. For more on Good Madam go to: shudder.com

This week, I sat down with Sheryl Lindros Dolan, Senior Regulatory Consultant with B&C and Senior Regulatory Specialist with our consulting affiliate, The Acta Group, and Meibao Zhuang, Ph.D., Senior Scientist/Regulatory Consultant with B&C and Acta, to discuss pesticide tolerances, what are they, how does the U.S. Environmental Protection Agency (EPA) develop them, and how well government and industry stakeholders communicate their utility in ensuring a safe and reliable food supply. We also wander into the complex world of soil amendments and adjuvants, so if you do not know what these are, listen up. ALL MATERIALS IN THIS PODCAST ARE PROVIDED SOLELY FOR INFORMATIONAL  AND ENTERTAINMENT PURPOSES. THE MATERIALS ARE NOT INTENDED TO CONSTITUTE LEGAL ADVICE OR THE PROVISION OF LEGAL SERVICES. ALL LEGAL QUESTIONS SHOULD BE ANSWERED DIRECTLY BY A LICENSED ATTORNEY PRACTICING IN THE APPLICABLE AREA OF LAW. ©2022 Bergeson & Campbell, P.C.  All Rights Reserved

The use of pesticides in global agriculture brings with it many problems including the killing of non-target, beneficial species as well as reversing pest-management gains from the use of conservation agriculture methods. In a newly published study by researchers at Penn State University, the use of plant cover, such as cover crops, was shown to […]

On this episode of The Best of Bias Podcast Lydell Dinero joined by AKA, Sean_ E, and LBZ discuss various sports and pop culture topics from the last couple weeks. Tune in as they discuss NFL Free agency, The struggle in the Ukraine, update on Tory lanez and Meg the stallion's case, and much more. Don't miss an all new episode of the Best of Bias Podcast.

The herbicide glyphosate has been used for decades, with increased use paralleling the adoption of genetically engineered crops. The compound has a strong safety record and international regulatory consensus stating no unique health risks when [...] The post 307 – Glyphosate Residues and Dietary Exposure first appeared on Talking Biotech Podcast.

Today on Life well lived,Omobola host Rev.(Dr.) Marisha Stewart,a divorce Coach,licensed Minister,and a podcast host. Dr. Marisha will be sharing her real-life experience as a divorcee,a co-parent,and also fulfilling her life purpose after her divorce.She has received healing from the residue and emotional trauma of divorce and she's on a mission to help women alike work through the challenges of divorce,single mum,co-parenting, to living a purposeful life. These and more she's set to contribute on the show.Be ready for an amazing time.Welcome to Life well lived by Omobola Stephen.Rev.(Dr.) Marisha Stewart website: www.iamthelionessqueen.comFacebook: Lioness QueenInstagram: revdrlionessqueen Twitter: lionessqueen727 

Sean and Dave talk through the art of cleaning LV flooring, which is the main maintenance required.  This daily process replaces all of the polishing and refinishing of VCT flooring.   Oh, and Sean says the LV flooring is now 60 % of the flooring market!  Better get on track with your education on this!   Sean DeVore  District Manager c: 352-630-9884 e: sean.devore@mannington.com

Sean and Dave talk through the art of cleaning LV flooring, which is the main maintenance required.  This daily process replaces all of the polishing and refinishing of VCT flooring.   Oh, and Sean says the LV flooring is now 60 % of the flooring market!  Better get on track with your education on this!   Sean DeVore  District Manager c: 352-630-9884 e: sean.devore@mannington.com

In this episode of Environmentality. I sit down with Dr. Lynne Carpenter-Boggs, Full Professor in the Crops and Soil Science Department at Washington State University to discuss nutrient cycling on many scales. We discuss the importance of returning nutrients back into agriculture systems in order to achieve more sustainable production systems, along with the potential to use composted bio-solids (human feces) and human bodies in this process.Dr. Carpenter-Boggs talks about the novelty of human composting, the regulations involved in pioneering the research and the status of this alternative funeral process today. We also chat about the importance of microorganisms in soils, along with many food production systems such as conservation, no-till and rotational agriculture systems. The focus of these agriculture systems being the preservation of soil health and stability.To learn more about her research, click here.To connect with Dr. Carpenter-Boggs, click here.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.11.377994v1?rss=1 Authors: Makarov, M., Meng, J., Tretyachenko, V., Srb, P., Brezinova, A., Giacobelli, V. G., Bednarova, L., Vondrasek, J., Dunker, A. K., Hlouchova, K. Abstract: It is well-known that the large diversity of protein functions and structures is derived from the broad spectrum of physicochemical properties of the 20 canonical amino acids. According to the generally accepted hypothesis, protein evolution was continuously associated with enrichment of this alphabet, increasing stability, specificity and spectrum of catalytic functions. Aromatic amino acids are considered the latest addition to genetic code. The main objective of this study was to test whether enzymatic catalysis can spare the aromatic amino acids (aromatics) by determining the effect of amino acid alphabet reduction on structure and function of dephospho-CoA kinase (DPCK). We designed two mutant variants of a putative DPCK from Aquifex aeolicus by substituting (i) Tyr, Phe and Trp or (ii) all aromatics (including His), i.e. ~10% of the total sequence. Their structural characterization indicates that removal of aromatic amino acids may support rich secondary structure content although inevitably impairs a firm globular arrangement. Both variants still possess ATPase activity, although with 150-300 times lower efficiency in comparison with the wild-type phosphotransferase activity. The transfer of the phosphate group to the dephospho-CoA substrate is however heavily uncoupled and only one of the variants is still able to perform the reaction. Here we provide support to the hypothesis that proteins in the early stages of life could support at least some enzymatic activities, despite lower efficiencies resulting from the lack of a firm hydrophobic core. Based on the presented data we hypothesize that further protein scaffolding role may be provided by ligands upon binding. Copy rights belong to original authors. Visit the link for more info

This week we talk about the nutritional value of crop residues for cattle. These acres are valuable but have a limited “shelf-life”. Tune in to find out the basic on this alternative grazing option. The Potential of Grazing Grain Sorghum Residue Following Harvest PSS-2607 Nitrate Toxicity in Livestock PSS-2903 Prussic Acid Poisoning PSS-2904

Today we look at some of the colonial legacies in discourses around girls’ education. With me are Chris Kirchgasler and Karishma Desai. They’ve recently published an article entitled, “’Girl’ in Crisis: Colonial Residues of Domesticity in Transnational School Reforms,” which was published in the Comparative Education Review. Chris Kirchgasler is an Assistant Professor at the University of Wisconsin-Madison and Karishma Desai is an assistant Professor at Rutgers Graduate School of Education. https://freshedpodcast.com/kirchgasler-desai/ -- Get in touch! Twitter: @FreshEdpodcast Facebook: FreshEd Email: info@freshedpodcast.com

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.29.360867v1?rss=1 Authors: Chen, Y.-R., Hsiao, N.-W., Huang, S.-S., Chang, C.-C., Lee, Y.-Z., Tsai, J.-R., Lin, H.-C., Toullec, J.-Y., Lee, C.-Y., Lyu, P.-C. Abstract: A neuropeptide (Sco-CHH-L), belonging to the crustacean hyperglycemic hormone (CHH) superfamily and preferentially expressed in the pericardial organs (POs) of the mud crab Scylla olivacea, was functionally and structurally studied. Its expression levels were significantly higher than the alternative splice form (Sco-CHH) in the POs and increased significantly after animals were subjected to a hypo-osmotic stress. Sco-CHH-L, but not Sco-CHH, significantly stimulated in vitro the Na+, K+-ATPase activity in the posterior (6th) gills. Furthermore, solution structure of Sco-CHH-L was resolved using nuclear magnetic resonance spectroscopy revealing that it has an N-terminal tail, three -helices (2, Gly9-Asn28; 3, His34-Gly38; 5, Glu62-Arg72), and a {pi}-helix ({pi}4, Cys43-Tyr53) and is structurally constrained by a pattern of disulfide bonds (Cys7-Cys43, Cys23-Cys39, Cys26-Cys52), which is characteristic of the CHH superfamily-peptides. Sco-CHH-L is topologically most similar to the molt-inhibiting hormone from the Kuruma prawn Marsupenaeus japonicus with a backbone root-mean-square-deviation of 3.12 [A]. Ten residues of Sco-CHH-L were chosen for alanine-substituted and the resulting mutants were functionally tested using the gill Na+, K+-ATPase activity assay, showing that the functionally important residues (I2, F3, E45, D69, I71, G73) are located at either end of the sequence, which are sterically close to each other and presumably constitutes the receptor binding sites. Sco-CHH-L was compared with other members of the superfamily revealing a molecular architecture, which is suggested to be common for the crustacean members of the superfamily, with the properties of the residues constituting the presumed receptor binding sites being the major factors dictating the ligand-receptor binding specificity. Copy rights belong to original authors. Visit the link for more info

The norm in conventional agricultural practice is to make the residue from old crops disappear, a practice that hasn't changed in over 70 years. Explore how California farmers and UC scientists are working together to perfect techniques to maximize the benefits of these crop residues to develop healthier more productive soils, reduce water consumption, and ensure sustainable agricultural production. Series: "Sustainable California" [Science] [Show ID: 32361]