Podcast appearances and mentions of Keith Rabois

Debate between Keith Rabois and Zach Weinberg on what tariffs are actually trying to accomplish. One core theme: Tariffs aren't fully about “bringing back factories,” but rather a negotiation tool to eliminate foreign trade barriers - ultimately aiming to increase free trade, not restrict it.We also got into:- What each of them would do if they were in charge- Whether the trade deficit is a meaningful metric or just a misunderstood talking point- If tariffs could be part of an initiative to replace income tax — shifting toward a more consumption-based tax system- If tariffs could successfully be used as a non-military tool to reduce drug supply to the US- If there's a major disconnect between the new administration's rhetoric and the actual economic goals behind the policyOne of the deepest economic conversations from the show's recent history — and a rare debate where both sides had real logic behind their views.(00:00) Introduction and Host's Biases(00:46) Keith's Perspective on Tariffs(03:05) Zach's Perspective and Clarifying Questions(05:14) Debating Tariff Strategies(07:45) Economic Implications and Free Trade(13:31) Trump's Tariff Policies and Goals(16:57) Global Trade and Protectionism(25:52) Final Thoughts on Tariffs and Trade(29:16) Discussion on Trade Tariffs and Partners(30:17) Impact of Tariffs on GDP and Debt(31:20) Political Coalitions and Trade Policies(32:00) Tariffs as Consumer Taxes(33:30) Debate on Trade Deficit and Tariff Rates(36:53) Regulatory Reforms and Economic Policies(47:25) Fentanyl Crisis and Trade Negotiations(51:06) Closing Remarks and Future TopicsExecutive Producer: Rashad AssirProducer: Leah ClapperMixing and editing: Justin HrabovskyCheck out Unsupervised Learning, Redpoint's AI Podcast: https://www.youtube.com/@UCUl-s_Vp-Kkk_XVyDylNwLA

Kyriakos is joined by Kian Sadeghi, the CEO of Nucleus Genomics, the leading company in the world, in genome testing.As of today, Nucleus has raised $32m, from some of the best investors in the world, such as Founders Fund, Seven Seven Six, and many more. 00:00 Introduction02:00 Jake Paul vs Mike Tyson: How the deal happened05:40 Make America Healthy Again in Fox News08:00 How to generate attention21:20 How Nucleus started28:00 Raising the first $33:00 How Kian raised from Keith Rabois from Founders Fund45:25 'The modern day emperor is founders'48:40 'The companies that win don't care about trends'49:30 'The two startup models'52:00 'AI is a negative signal'55:50 'Join the founder that is insane'56:50 Nucleus product evolution57:20 The 23andMe acquisition1:08:00 'DNA future and family planning'1:16:00 Raising the Series A1:21:00 Deadlifts

This week on Turpentine VC, we're re-releasing Erik Torenberg's interview with Logan Bartlett, partner at Redpoint and host of The Logan Bartlett Show. They discuss Redpoint's approach to venture, patterns in the VC ecosystem, and the strategies of venture's most consequential firms. — 

LaBossiere Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Keith Rabois is a Managing Partner at Khosla Ventures and the CEO of OpenStore, which acquires small direct-to-consumer businesses. Keith co-founded Opendoor and led the first institutional investments in DoorDash and Affirm. He has early stakes in YouTube, Palantir, Lyft, Airbnb, Eventbrite, and Wish, and also led investments in Faire, Ramp, Trade Republic, and Stripe. He's regarded as one of the greatest early stage investors.Keith began his career in the industry as a senior executive at PayPal and subsequently served in influential roles at LinkedIn and as chief operating officer of Square. As a board member, Keith guided Yelp and Xoom from inception to IPO, and served on the board of Reddit from 2012-2018.0:00 - Intro1:56 - Great Founders and the Bottleneck to Innovation4:35 - Vertical Integration6:24 - The Hollywood Model of Startups7:41 - The “Why Now?” in Company-Building9:50 - Multi-Product Companies10:58 - Iteration and Pivots12:52 - Picking Co-Founders14:51 - Identifying Mispriced Talent17:20 - Attracting Talent20:57 - Assessing Talent24:02 - Doing References25:56 - Closing Hires28:28 - Thinking 6 Months Ahead31:36 - How Long Should You Interview For?33:28 - Creating a Monopoly on Talent35:44 - Raising Capital37:40 - Screening Investors41:21 - Building a Board44:11 - Triaging and Identifying Problems47:59 - Writing vs Editing and Consistent Voice49:34 - Creating Transparency50:50 - Barrels and Ammunition54:55 - Task-Relevant Maturity56:40 - On Delegating59:21 - Measuring Inputs vs Outputs1:02:58 - Underrated Metrics1:05:22 - What Should More People Be Thinking About?

LaBossiere Podcast Key Takeaways  World-class founders are the scarce resource: Every investor is chasing after the 5-10-15 founders a year that have a non-zero probability of rearranging the planet to their willYou either have a superpower, or you don't; you need to be in the top 1% on some dimension or you have no chance of creating the next Nvidia Identify a crack in the world where things are volatile or in transition, and build solutions that address those opportunistic gaps  How to attract talent: Embrace and foster strong cultural principles that can differentiate your company from other companies – and be sure that those principles are authentic The framework for understanding when to promote comes down to whether an employee's growth rate is outpacing the growth of the company  Knowing how much capital to raise: Identify the two or three inflection points that will make the startup successful, then work backward from those and calculate the capital needed to reach each of them The biggest mistake that founders make is that they don't do reference checks on investors Most MBA-esque wisdom is bad: People default to hiring because they want to manage people; new teams get created but nothing new gets done – this creates complacency and makes it challenging to tell the good employees from the bad onesThe job of the CEO is to clarify and simplify the company's initiatives, then strategically allocate resources against those goals – all done in the interest of ensuring a consistent voice It is the CEO's responsibility to disseminate as much high-signal information as possible so that everybody has the same context; doing this increases the probability that more people will naturally arrive at the correct decision Making the decision and deciding that you are going to be successful is more important than the option value of waiting Focus on inputs not outputs: People within your organization won't take sufficient risks if the perception is that results are the only thing that matters Challenge yourself: “You either want to write something worth reading, or do something worth writing about.” – Ben Franklin Read the full notes @ podcastnotes.orgKeith Rabois is a Managing Partner at Khosla Ventures and the CEO of OpenStore, which acquires small direct-to-consumer businesses. Keith co-founded Opendoor and led the first institutional investments in DoorDash and Affirm. He has early stakes in YouTube, Palantir, Lyft, Airbnb, Eventbrite, and Wish, and also led investments in Faire, Ramp, Trade Republic, and Stripe. He's regarded as one of the greatest early stage investors.Keith began his career in the industry as a senior executive at PayPal and subsequently served in influential roles at LinkedIn and as chief operating officer of Square. As a board member, Keith guided Yelp and Xoom from inception to IPO, and served on the board of Reddit from 2012-2018.0:00 - Intro1:56 - Great Founders and the Bottleneck to Innovation4:35 - Vertical Integration6:24 - The Hollywood Model of Startups7:41 - The “Why Now?” in Company-Building9:50 - Multi-Product Companies10:58 - Iteration and Pivots12:52 - Picking Co-Founders14:51 - Identifying Mispriced Talent17:20 - Attracting Talent20:57 - Assessing Talent24:02 - Doing References25:56 - Closing Hires28:28 - Thinking 6 Months Ahead31:36 - How Long Should You Interview For?33:28 - Creating a Monopoly on Talent35:44 - Raising Capital37:40 - Screening Investors41:21 - Building a Board44:11 - Triaging and Identifying Problems47:59 - Writing vs Editing and Consistent Voice49:34 - Creating Transparency50:50 - Barrels and Ammunition54:55 - Task-Relevant Maturity56:40 - On Delegating59:21 - Measuring Inputs vs Outputs1:02:58 - Underrated Metrics1:05:22 - What Should More People Be Thinking About?

Keith Rabois is a Managing Partner at Khosla Ventures and the CEO of OpenStore, which acquires small direct-to-consumer businesses. Keith co-founded Opendoor and led the first institutional investments in DoorDash and Affirm. He has early stakes in YouTube, Palantir, Lyft, Airbnb, Eventbrite, and Wish, and also led investments in Faire, Ramp, Trade Republic, and Stripe. He's regarded as one of the greatest early stage investors.Keith began his career in the industry as a senior executive at PayPal and subsequently served in influential roles at LinkedIn and as chief operating officer of Square. As a board member, Keith guided Yelp and Xoom from inception to IPO, and served on the board of Reddit from 2012-2018.0:00 - Intro1:56 - Great Founders and the Bottleneck to Innovation4:35 - Vertical Integration6:24 - The Hollywood Model of Startups7:41 - The “Why Now?” in Company-Building9:50 - Multi-Product Companies10:58 - Iteration and Pivots12:52 - Picking Co-Founders14:51 - Identifying Mispriced Talent17:20 - Attracting Talent20:57 - Assessing Talent24:02 - Doing References25:56 - Closing Hires28:28 - Thinking 6 Months Ahead31:36 - How Long Should You Interview For?33:28 - Creating a Monopoly on Talent35:44 - Raising Capital37:40 - Screening Investors41:21 - Building a Board44:11 - Triaging and Identifying Problems47:59 - Writing vs Editing and Consistent Voice49:34 - Creating Transparency50:50 - Barrels and Ammunition54:55 - Task-Relevant Maturity56:40 - On Delegating59:21 - Measuring Inputs vs Outputs1:02:58 - Underrated Metrics1:05:22 - What Should More People Be Thinking About?

Cette semaine, je reçois Anis Bennaceur, le cofondateur et CEO de Attention, une startup qui utilise l'IA pour transformer la manière dont les commerciaux travaillent et interagissent avec leur CRM.Au cours de cet épisode, nous sommes revenus sur le parcours fascinant d'Anis : de ses débuts dans la finance à son expérience chez Tinder, en passant par le lancement de ses premières startups avant Attention. Il partage avec nous les pivots stratégiques et technologiques qui ont permis à Attention de passer de 0 à 1 million d'ARR en 10 mois, ainsi que son approche du growth hacking et du développement produit.Nous avons parlé de l'évolution du métier de commercial avec l'IA :Remplissage automatique du CRM et gain de productivitéAutomatisation des tâches sales avec des agents IAPerspectives sur l'avenir des équipes commerciales et l'impact des voice agentsStratégies de croissance et différenciation face aux copycatsEnfin, Anis nous partage ses recommandations de lecture et ressources pour mieux comprendre la vente, l'opérationnel et l'impact de l'IA.Vous pouvez suivre Anis sur LinkedIn.Bonne écoute !Mentionnés pendant l'épisode :

Kareem Zaki shares the founding and development of Thrive Capital, emphasizing their strategy of opportunism combined with a focus on category-defining companies, their unique approach to talent cultivation and company-building in various sectors, especially healthcare, and their intentional media minimalism. — 

Today on Moment of Zen, we're bringing you the third episode of "This Won't Last", the newest show from Turpentine. Keith Rabois, Logan Bartlett, Kevin Ryan, and Zach Weinberg dissect the 2025 political landscape in a spirited discussion of Trump's evolved messaging and surprising tech industry backing. The conversation weaves through immigration policy, corporate political neutrality, and market dynamics - from Silicon Valley's rightward shift to urban crime challenges and insurance markets and explores how America's tech-policy nexus is reshaping in real-time. —

This week on Upstream, we're sharing Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's discussion of the 2025 post-election landscape centered on Trump's victory, examining his evolved approach and tech industry support, while exploring interconnected policy challenges around immigration, corporate politics, urban crime, and market regulation in areas like wildfire insurance and healthcare. —

Barbara Doran of BD8 Capital Partners and Crossmark Global Investments' Bob Doll give their playbook for the market as earnings ramp up. Earnings from CSX and Texas Instruments. Susquehanna's Christopher Rolland joins to dissect TXN earnings and the chip sector, while Sheila Kahyaoglu from Jefferies on Boeing Q4 preannouncement.Jon Fortt sits down exclusively with Twilio CEO Khozema Shipchandler on the company's new growth targets. Keith Rabois of Khosla Ventures on the Trump economy, Musk vs. Altman, and the future of Stargate. 

Today on Turpentine VC, we're releasing one of our most popular episodes: Erik's interview with Aydin Senkut, founder and managing partner of Felicis Ventures. Aydin discusses the evolution and distinct strategies of Felicis Ventures, their focus on mental health, and insights on successful generalist investing in venture capital. — 

This episode of Turpentine VC was recorded in front of a live audience in San Francisco in October 2018.Keith Rabois discusses his frameworks for identifying talent, sharing anecdotes about notable operators and companies like PayPal, LinkedIn, and Square. He emphasizes the importance of talent assessment, strategic thinking, and offers career advice while reflecting on his own experiences and observations. — 

In this episode of The Eric Ries Show, I'm joined by Siqi Chen, a four-time founder and the CEO and CFO of his latest venture, Runway. Runway offers a modern, user-friendly platform for financial modeling, headcount planning, and departmental budgeting—proudly branding itself as “the finance platform your team doesn't hate.” With its distinctive marketing and brand-building approach, Runway has garnered significant attention. (Full disclosure: I'm an investor in the company.) Siqi and I discuss his journey from building some of the most viral social games in Silicon Valley to founding Runway. We also delve into the challenges faced by technical founders, the art of viewing a business as a product, and how Siqi has sharpened his strategic thinking. Other key topics include: • Lessons from founding Serious Business • Critiques of Zynga's strategy and the story of selling to them • Practical advice for building trust • Insights into Leaders in Tech and Stanford's GSB program • The importance of crafting clear, universally understood company values • An overview of Runway's platform, mission, and values • A fresh take on the fallacy of work-life balance • And so much more! — Brought to you by: Vanta – Automate compliance, manage risk, and prove trust—continuously. ⁠⁠Get $1,000 off⁠⁠. — Where to find Siqi Chen: • LinkedIn: https://www.linkedin.com/in/siqic/ • X: https://x.com/blader/ • Instagram: https://www.instagram.com/blader/ • Facebook:  https://www.facebook.com/founder/ Where to find Eric: • Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ericries.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  • Podcast: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ericriesshow.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  • YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@theericriesshow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  — In This Episode We Cover: (00:00) Meet Siqi Chen (02:30) How Siqi came up with the idea for Mafia and the early years of gaming on Facebook (05:10) The early investors in Mafia (05:36) Siqi's meeting with Keith Rabois and Max Levchin (08:15) How Siqi was influenced by the Lean Startup approach (11:04) How quickly Siqi's career took off after moving to San Francisco  (11:48) Founding Serious Business and creating Friends for Sale (14:20) How Serious Business raised $5 million (16:20) Why Serious Business sold to Zynga  (17:20) The importance of prioritizing the business as much as the product (19:11) Siqi's learnings and advice for new founders  (23:25) What Siqi learned working at Zynga (27:18) Siqi's time running product  (29:20) Criticisms of Zynga and how they lost Eric's trust (33:42) The importance of trust and maintaining vision and mission (39:15) An overview of Runway  (44:38) What inspired Siqi to create Runway (50:43) What Siqi learned from user interviews (52:07) An example of time wasting inside a company (53:24) The values at Runway and why they changed  (58:35) Why you should write reflective values after having a high-performance team (1:00:40) How Leaders in Tech shaped Siqi's thoughts on values and building trust (1:03:13) How open feedback builds trust (1:08:20) The purpose of Runway (1:11:34) Siqi's struggles with strategy planning  (1:13:31) A top down approach to entrepreneurship and why it's not common (1:16:38) The importance of employees understanding their contributions and impact  (1:18:55) How Runway leverages AI  (1:22:12) Runway's dramatic launch with a timed lock (1:23:04) How Runway communicates value to customers  (1:24:54) Runway's process for brand building and high-quality design  (1:28:40) Lightning round You can find the transcript and references at ⁠⁠⁠⁠⁠https://www.ericriesshow.com/⁠⁠⁠⁠ — Production and marketing by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://penname.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Eric may be an investor in the companies discussed.

(0:00) The Besties welcome Keith Rabois! (4:01) Keith explains why he returned to Khosla Ventures, the differences between Founders Fund and Khosla, and his husband Jacob Helberg's role in Trump Admin (13:09) Business acumen of Trump's cabinet and appointees, diversity of opinion (25:59) Google's new quantum chip: potential impact on encryption, cryptography, and more (43:50) Apple developing new server chip for AI inference, iOS flop, why its product culture is failing (54:30) TikTok panics after appeals court upholds the "divest-or-ban" law, with a January 19th deadline (1:03:55) State of Venture Capital, why Stripe is still private, thoughts on crypto Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow Keith: https://x.com/rabois Follow on X: https://x.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@theallinpod Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://x.com/yung_spielburg Intro Video Credit: https://x.com/TheZachEffect Referenced in the show: https://www.tiktok.com/@frankielapenna/video/7010077215576575238 https://www.axios.com/2024/12/06/trump-billionaires-cabinet-elon-musk https://blog.google/technology/research/google-willow-quantum-chip https://www.nature.com/articles/s41586-024-08449-y https://research.google/blog/suppressing-quantum-errors-by-scaling-a-surface-code-logical-qubit https://quantumai.google/roadmap https://en.wikipedia.org/wiki/Hartmut_Neven https://en.wikipedia.org/wiki/Double-slit_experiment https://www.discovery.com/science/Double-Slit-Experiment https://en.wikipedia.org/wiki/Schr%C3%B6dinger%27s_cat https://www.theinformation.com/articles/apple-is-working-on-ai-chip-with-broadcom?rc=pxkrxo https://x.com/rabois/status/870673635375104000 https://www.amazon.com/Company-Giants-Conversations-Visionaries-Digital/dp/0070329656 https://www.cnn.com/2024/12/09/tech/bytedance-tiktok-halt-us-ban-intl/index.html https://apnews.com/article/tiktok-us-ban-sale-china-congress-de12b4d22aa8095e62cb0982a6e62235 https://apnews.com/article/tiktok-ban-congress-bill-1c48466df82f3684bd6eb21e61ebcb8d https://pitchbook.com/news/reports/q3-2024-pitchbook-nvca-venture-monitor https://www.cnbc.com/2024/12/12/servicetitan-starts-trading-on-nasdaq-after-ipo.html https://www.nytimes.com/2024/12/11/business/dealbook/ftc-trump-ferguson-khan.html https://www.ben-evans.com/benedictevans/2021/6/15/antitrust https://www.bloomberg.com/news/articles/2024-12-05/convertible-bond-arbs-are-making-microstrategy-wall-street-s-hottest-trade

0xDesigner is an designer, imagineer and self-described provocateur. He is currently working on Design Everydays where he shares design concepts that explore ways web3 can be more useful, exciting or easier to use. Follow him on Warpcast @0xdesigner and on X @0xDesigner. Mint this episode for free onchain on Base at ⁠⁠pods.media/pod-of-jake/187-0xdesigner For more episodes, go to ⁠⁠podofjake.com⁠⁠. Previous guests include ⁠⁠Mark Cuban⁠⁠, ⁠⁠Vitalik Buterin⁠⁠, ⁠⁠Brian Armstrong⁠⁠, ⁠⁠Balaji Srinivasan⁠⁠, ⁠⁠Keith⁠⁠ ⁠⁠Rabois⁠⁠, ⁠⁠Ali Spagnola⁠⁠, ⁠⁠Anthony Pompliano⁠⁠, ⁠⁠Raoul Pal⁠⁠, ⁠⁠Julia Galef⁠⁠, ⁠⁠Jack Butcher⁠⁠, ⁠⁠Tim Draper⁠⁠, and over 100 others alike. Learn from founders and CEOs of companies like ⁠⁠OpenAI⁠⁠, ⁠⁠Coinbase⁠⁠, ⁠⁠Solana⁠⁠, ⁠⁠Polygon⁠⁠, ⁠⁠AngelList⁠⁠⁠, ⁠⁠Oura⁠⁠⁠, and ⁠⁠Replit⁠⁠, and investors from ⁠⁠Founders⁠⁠ ⁠⁠Fund⁠⁠, ⁠⁠a16z⁠⁠, ⁠⁠Union Square Ventures⁠⁠, and many more. I appreciate your support and hope you enjoy. Thanks to ⁠⁠⁠Chase Devens⁠⁠⁠ for the show notes and ⁠⁠⁠Yiction⁠⁠⁠ for the music. Lastly, I love hearing from fans of the pod. Feel free to email me any time at ⁠⁠jake@blogofjake.com⁠⁠. Thank you!

Camila Russo is the Founder of The Defiant, a media company focusing on decentralized finance, and the author of The Infinite Machine, the most read book on the history of Ethereum. Previously, she was a markets and crypto reporter at Bloomberg News. Follow her on X ⁠@CamiRusso. Mint this episode for free onchain on Base at ⁠⁠pods.media/pod-of-jake/186-camila-russo For more episodes, go to ⁠⁠podofjake.com⁠⁠. Previous guests include ⁠⁠Mark Cuban⁠⁠, ⁠⁠Vitalik Buterin⁠⁠, ⁠⁠Brian Armstrong⁠⁠, ⁠⁠Balaji Srinivasan⁠⁠, ⁠⁠Keith⁠⁠ ⁠⁠Rabois⁠⁠, ⁠⁠Ali Spagnola⁠⁠, ⁠⁠Anthony Pompliano⁠⁠, ⁠⁠Raoul Pal⁠⁠, ⁠⁠Julia Galef⁠⁠, ⁠⁠Jack Butcher⁠⁠, ⁠⁠Tim Draper⁠⁠, and over 100 others alike. Learn from founders and CEOs of companies like ⁠⁠OpenAI⁠⁠, ⁠⁠Coinbase⁠⁠, ⁠⁠Solana⁠⁠, ⁠⁠Polygon⁠⁠, ⁠⁠AngelList⁠⁠⁠, ⁠⁠Oura⁠⁠⁠, and ⁠⁠Replit⁠⁠, and investors from ⁠⁠Founders⁠⁠ ⁠⁠Fund⁠⁠, ⁠⁠a16z⁠⁠, ⁠⁠Union Square Ventures⁠⁠, and many more. I appreciate your support and hope you enjoy. Thanks to ⁠⁠⁠Chase Devens⁠⁠⁠ for the show notes and ⁠⁠⁠Yiction⁠⁠⁠ for the music. Lastly, I love hearing from fans of the pod. Feel free to email me any time at ⁠⁠jake@blogofjake.com⁠⁠. Thank you!

In this episode of History 102, 'WhatIfAltHist' creator Rudyard Lynch is joined by business development executive and agriculture technology industry entrepreneur Austin Padgett and explore 17th century Western Europe's pivotal transformation. They examine how the Protestant-Catholic divide, parallel to modern political polarization, shaped warfare, science, and economics. The conversation reveals how the Dutch and English success in breaking monopolies and embracing agricultural innovation set the stage for the Industrial Revolution and modern capitalism. --

Keith Rabois, early investor in Affirm, Stripe, DoorDash and others, on why he is supporting Trump in the election—and why he changed his stance as a former Never Trumper. Chamber of Commerce CEO Suzanne Clark talks the business issues on the ballot and what is most important to the CEOs she represents. Plus, Lumen CEO Kate Johnson on her company's new deal with Google Cloud and why Big Tech is partnering with Lumen for building AI networks. Plus, investors sour on Super Micro's latest earnings. 

W1NTΞR is the co-creator of BasePaint, a collaborative pixel art project built on Base. He specializes in unique smart contracts, user interfaces, and everything in between. W1NTΞR has built several crypto projects in the last few years and worked for FAANG companies and startups before that. Follow him on X @w1nt3r_eth and on Farcaster @w1nt3r. Mint this episode for free onchain on Base at ⁠pods.media/pod-of-jake/184-w1nt3r For more episodes, go to ⁠⁠podofjake.com⁠⁠. Previous guests include ⁠⁠Mark Cuban⁠⁠, ⁠⁠Vitalik Buterin⁠⁠, ⁠⁠Brian Armstrong⁠⁠, ⁠⁠Balaji Srinivasan⁠⁠, ⁠⁠Keith⁠⁠ ⁠⁠Rabois⁠⁠, ⁠⁠Ali Spagnola⁠⁠, ⁠⁠Anthony Pompliano⁠⁠, ⁠⁠Raoul Pal⁠⁠, ⁠⁠Julia Galef⁠⁠, ⁠⁠Jack Butcher⁠⁠, ⁠⁠Tim Draper⁠⁠, and over 100 others alike. Learn from founders and CEOs of companies like ⁠⁠OpenAI⁠⁠, ⁠⁠Coinbase⁠⁠, ⁠⁠Solana⁠⁠, ⁠⁠Polygon⁠⁠, ⁠⁠AngelList⁠⁠⁠, ⁠⁠Oura⁠⁠⁠, and ⁠⁠Replit⁠⁠, and investors from ⁠⁠Founders⁠⁠ ⁠⁠Fund⁠⁠, ⁠⁠a16z⁠⁠, ⁠⁠Union Square Ventures⁠⁠, and many more. I appreciate your support and hope you enjoy. Thanks to ⁠⁠⁠Chase Devens⁠⁠⁠ for the show notes and ⁠⁠⁠Yiction⁠⁠⁠ for the music. Lastly, I love hearing from fans of the pod. Feel free to email me any time at ⁠⁠jake@blogofjake.com⁠⁠. Thank you!

This week on Econ 102, Noah Smith and Erik Torenberg delivers a masterful analysis of American progressivism's rise, fall, and potential future resurrection as a class-focused movement in the 2030s. For full show notes, visit: https://highlightai.com/share/c29e2f67-3580-4753-913b-f87c744c6118 --

Keith Rabois, Logan Bartlett, Kevin Ryan, and Zach Weinberg share a rare anecdote about the first venture investment into OpenAI, lay out the bull and bear case for the leading AI companies and discuss regulatory chess games at play in American politics. For full show notes, visit: https://highlightai.com/share/8a2ea800-ab8a-4115-80c7-04c059d3fb10  —

In this episode of Moment of Zen, Erik Torenberg sits down with Tim Urban, writer of the popular blog Wait But Why, and author of the 2023 book What's Our Problem? where he offers a framework for thinking about our chaotic political landscape. Tim unpacks the clash between freedom and equality in modern society. He explores how social justice movements and political extremes threaten open dialogue. Urban argues for a return to classical liberal values, challenging listeners to consider: Are we fostering true diversity of thought, or silencing dissent in the name of progress?

Keith Rabois is the Managing Director at Khosla Ventures & CEO at OpenStore. Mike Shebat is the Co-Founder & CEO at Traba. This conversation was recorded at the BUILD Summit in New York. In this conversation, we discuss how elite entrepreneurs stand out, the importance of an ambitious culture, how to build a great team, utilizing AI, their current investing themes, and more.  ======================= Buy book: https://www.amazon.com/Live-Extraordinary-Life-Anthony-Pompliano/dp/0857199927/ ======================= Xapo Bank, the world's first fully licensed Bitcoin-enabled bank, offers military-grade security with an unmatched blend of physical and digital security, as well as pioneering regulatory oversight, so your funds are always protected. Beyond secure storage, they enable you to grow and use your Bitcoin. Earn daily interest in Bitcoin, spend with zero FX fees using a global card, and make instant payments via the Lightning Network for unrivalled access and convenience. Visit https://www.xapobank.com/pomp to join. ======================= Pomp writes a daily letter to over 265,000+ investors about business, technology, and finance. He breaks down complex topics into easy-to-understand language while sharing opinions on various aspects of each industry. You can subscribe at https://pomp.substack.com/ ======================= View 10k+ open startup jobs: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://dreamstartupjob.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Enroll in my Crypto Academy: https://www.thecryptoacademy.io/

In this episode of World Class with Chris Vasquez, we dive into the mind of one of Silicon Valley's most influential entrepreneurs and investors, Keith Rabois. Keith, a founding member of PayPal and an early investor in companies like LinkedIn, Square, and Yelp, shares his profound insights on scaling world-class companies, leadership, and what it takes to succeed in the fast-paced world of startups. Throughout this conversation, Keith opens up about his decision-making frameworks, operating fast-growing startups, and hiring the right executives. He discusses why talented salespeople sometimes flop as VPs, the importance of knowing when to delegate versus doing things yourself, and how to manage time effectively as a leader. Keith also reveals his personal motivation, including how proving people wrong has fueled his incredible drive. In a deep dive into current events, Keith shares his thoughts on the Kamala vs. Trump dilemma and explains why he believes the upcoming election could result in a massive win for Trump—providing a candid perspective on the political landscape and what's at stake for the country's future. Chapters: 1:25 Founder Mode Explained 4:06 Why Sometimes Talented Salespeople Flop as VPs 4:57 Delegate vs Doing Yourself 9:00 Scaling Fast-Growing Startups 14:42 Key Executive Hires 16:20 Hiring Mistakes 17:25 Time Management Hacks 31:03 The Kamala vs Trump Dilemma 47:54 World Class LifeKey topics in this episode include: • Founder Mode Explained: Keith's approach to leadership and thriving in a startup environment • Why Talented Salespeople Flop as VPs: The mismatch of skills at the executive level • Delegate vs Doing: When to delegate and when to take charge yourself • Scaling Fast-Growing Startups: Strategies for rapid growth in the tech industry • Decision Frameworks & SOPs: Keith's structured approach to running a business • Investment Decision-Making Model: Keith's method for evaluating high-potential investments • Key Executive Hires & Hiring Mistakes: How to build an effective executive team and common pitfalls to avoid • Motivation & Success: Keith's insights on what drives him, and using negativity as fuel for growth • Time Management Hacks: How to manage your time as a startup leader • The Kamala vs Trump Dilemma: Keith's perspective on the 2024 election and why he thinks Trump will come out on top • The World Class Life: Insights into what it takes to live at the highest level of success • Growth Philosophy: Keith's personal approach to growing businesses and people

This week on Econ 102, Noah Smith and Erik Torenberg tackle the shift in economic research from empirical studies to "big think" theories, critically examine Acemoglu's work on institutions and AI's impact on jobs, and debate the future of economics as a science. --

Today on Moment of Zen, we're bringing you the second episode of "This Won't Last", the newest show from Turpentine. Keith Rabois, Logan Bartlett, Kevin Ryan, and Zach Weinberg share a rare anecdote about the first venture investment into OpenAI, lay out the bull and bear case for the leading AI companies and discuss regulatory chess games at play in American politics.

In this episode of History 102, In this episode of History 102, 'WhatIfAltHist' creator Rudyard Lynch and Erik Torenberg dive deep into the fascinating yet often overlooked realm of 17th century Eastern Europe. Join Rudyard and Erik as they bring this pivotal era to life: unravel the rise and fall of Poland-Lithuania, Russia's emergence as a great power, and Sweden's surprising dominance, and discover how Cossacks, Ottoman Turks, and visionary leaders shaped the region's destiny. With a blend of scholarly insight and engaging storytelling, Rudyard uncovers the absurdities, triumphs, and tragedies that defined this transformative century

In this episode, Sasha Orloff sits down with Blake Hutchison, CEO of Flippa, the leading platform for buying and selling online businesses. Blake shares insights from his career (Xero, Lonely Planet, Good44), and explains how Flippa operates as the ‘investment bank for the 99%,' providing a marketplace for subscale business transactions. The episode dives into the opportunities presented by the marketplace, key deal characteristics, and the different buyer segments. They also discuss the importance of financial literacy for subscale businesses, provide tips for first-time buyers, and offer predictions for the future of flipping businesses.

This week, Noah Smith and Erik Torenberg discuss the political nuances that influence the Republican and Democratic parties in the U.S. They explore the historical shifts in party dynamics, immigration policies, and the evolving economic strategies under potential future administrations.  --

Nathan and co-host Stephen Parker delve into the world of AI video generation with Anastasis Germanidis, Co-Founder and CTO of Runway. This episode of The Cognitive Revolution explores the cutting-edge technology behind Runway's Gen 3 models and their impact on the creative industry. From emergent properties in scaled-up models to the democratization of video creation, join us for an illuminating discussion on the future of AI-generated content and its potential to reshape entertainment and culture. Check out Runway here: https://runwayml.com Apply to join over 400 Founders and Execs in the Turpentine Network: https://www.turpentinenetwork.co/ SPONSORS: Notion: Notion offers powerful workflow and automation templates, perfect for streamlining processes and laying the groundwork for AI-driven automation. With Notion AI, you can search across thousands of documents from various platforms, generating highly relevant analysis and content tailored just for you - try it for free at https://notion.com/cognitiverevolution Weights & Biases RAG++: Advanced training for building production-ready RAG applications. Learn from experts to overcome LLM challenges, evaluate systematically, and integrate advanced features. Includes free Cohere credits. Visit https://wandb.me/cr to start the RAG++ course today. Omneky: Omneky is an omnichannel creative generation platform that lets you launch hundreds of thousands of ad iterations that actually work customized across all platforms, with a click of a button. Omneky combines generative AI and real-time advertising data. Mention "Cog Rev" for 10% off https://www.omneky.com/ Oracle: Oracle Cloud Infrastructure (OCI) is a single platform for your infrastructure, database, application development, and AI needs. OCI has four to eight times the bandwidth of other clouds; offers one consistent price, and nobody does data better than Oracle. If you want to do more and spend less, take a free test drive of OCI at https://oracle.com/cognitive RECOMMENDED PODCAST: This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel ft their hottest takes on the future of tech, business, and venture capital. Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz CHAPTERS: (00:00:00) About the Show (00:00:22) About the Episode (00:03:05) Introduction and AI for Creative Work (00:03:39) Video Generation as World Modeling (00:05:52) Emergent Properties in Scaled Models (00:08:44) Importance of Architecture vs Data (00:10:57) Multimodal Models (00:15:52) Sponsors: Notion | Weights & Biases RAG++ (00:18:37) Video Understanding and AGI (00:25:03) AI Agents for Video Creation (00:27:30) Runway's culture of shipping (00:29:20) Balancing Research Publication and Strategy (00:33:19) Sponsors: Omneky | Oracle (00:34:40) Features Variety Release Cycle (00:36:54) Power Users (00:38:56) Interactive Video (00:40:40) Scaling Challenges (00:42:21) Future of Creativity (00:45:24) Competing with Giants (00:47:39) Model Divergence (00:49:28) Disclosure vs. Strategy (00:51:19) Runway ML's API (00:54:23) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://www.linkedin.com/in/nathanlabenz/

In this episode of The Cognitive Revolution, Nathan explores unconventional approaches to AI safety with Judd Rosenblatt and Mike Vaiana from AE Studio. Discover how this innovative company pivoted from brain-computer interfaces to groundbreaking AI alignment research, producing two notable results in cooperative and less deceptive AI systems. Join us for a deep dive into biologically-inspired approaches that offer hope for solving critical AI safety challenges. Self-Modeling: https://arxiv.org/abs/2407.10188 Self-Other Distinction Minimization: https://www.alignmentforum.org/posts/hzt9gHpNwA2oHtwKX/self-other-overlap-a-neglected-approach-to-ai-alignment Neglected approaches blog post: https://www.lesswrong.com/posts/qAdDzcBuDBLexb4fC/the-neglected-approaches-approach-ae-studio-s-alignment Apply to join over 400 Founders and Execs in the Turpentine Network: https://www.turpentinenetwork.co/ SPONSORS: WorkOS: Building an enterprise-ready SaaS app? WorkOS has got you covered with easy-to-integrate APIs for SAML, SCIM, and more. Join top startups like Vercel, Perplexity, Jasper & Webflow in powering your app with WorkOS. Enjoy a free tier for up to 1M users! Start now at https://bit.ly/WorkOS-Turpentine-Network Weights & Biases Weave: Weights & Biases Weave is a lightweight AI developer toolkit designed to simplify your LLM app development. With Weave, you can trace and debug input, metadata and output with just 2 lines of code. Make real progress on your LLM development and visit the following link to get started with Weave today: https://wandb.me/cr 80,000 Hours: 80,000 Hours offers free one-on-one career advising for Cognitive Revolution listeners aiming to tackle global challenges, especially in AI. They connect high-potential individuals with experts, opportunities, and personalized career plans to maximize positive impact. Apply for a free call at https://80000hours.org/cognitiverevolution to accelerate your career and contribute to solving pressing AI-related issues. Omneky: Omneky is an omnichannel creative generation platform that lets you launch hundreds of thousands of ad iterations that actually work customized across all platforms, with a click of a button. Omneky combines generative AI and real-time advertising data. Mention "Cog Rev" for 10% off https://www.omneky.com/ RECOMMENDED PODCAST: This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel ft their hottest takes on the future of tech, business, and venture capital. Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz CHAPTERS: (00:00:00) About the Show (00:00:22) Sponsors: WorkOS (00:01:22) About the Episode (00:05:18) Introduction and AE Studio Background (00:11:37) Keys to Success in Building AE Studio (00:16:57) Sponsors: Weights & Biases Weave | 80,000 Hours (00:19:37) Universal Launcher and Productivity Gains (00:24:44) 100x Productivity Increase Explanation (00:31:46) Brain-Computer Interface and AI Alignment (00:38:05) Sponsors: Omneky (00:38:30) Current State of NeuroTech (00:44:00) Survey on Neglected Approaches in AI Alignment (00:50:41) Self-Modeling and Biological Inspiration (00:57:48) Technical Details of Self-Modeling (01:06:17) Self-Other Distinction Minimization (01:12:44) Implementation in Language Models (01:19:00) Compute Costs and Scaling Considerations (01:24:27) Consciousness Concerns and Future Work (01:40:24) Evaluating Neglected Approaches (01:55:56) Closing Thoughts and Policy Considerations (01:59:25) Outro

This episode centers on the alarming issue of declining fertility rates worldwide, examining specific country examples such as Japan, South Korea, and Turkey, and the societal and technological implications of these demographic changes.  Samo Burja and Erik Torenberg explore potential interventions, such as tax breaks for families, and the possibility of extreme measures like state-managed reproduction programs. They also tackle cultural and economic factors influencing fertility and the urgency of addressing this underpopulation crisis to prevent civilizational collapse.  --

This week, Noah Smith and Erik Torenberg unpack China's economic strategies under Xi Jinping, from the controversial tech crackdown to the ambitious Belt and Road Initiative. They explore the intricacies of international currency dynamics, dissect Ben Bernanke's pivotal role in the 2008 financial crisis, and examine the complex effects of brain drain on developing nations. --

Today on Moment of Zen, Samo Burja and Rudyard Lynch return for for a mind-bending discussion and deep dive into the concept of "long ripples" — how ideas and events from the distant past continue to shape our present and future in unexpected ways. From Plato's influence on modern political movements to the unforeseen consequences of the Industrial Revolution, this conversation challenges our understanding of historical cause and effect. Are we truly progressing, or are we caught in cycles we fail to recognize? Can we learn from the past, or are we doomed to repeat it in new, technologically-amplified ways? This episode is a rollercoaster ride through time, technology, and human nature, forcing us to reconsider our place in the grand sweep of history.  Both Samo and Rudyard are hosts of Turpentine shows, Live Players and History 102, respectively. CHECK OUT: Live Players: Spotify: https://open.spotify.com/show/5fbMTkHBnom1JIBWYNVBK1 Apple: https://podcasts.apple.com/us/podcast/live-players-with-samo-burja-and-erik-torenberg/id1718925188 History 102: Spotify: https://open.spotify.com/show/36Kqo3BMMUBGTDo1IEYihm Apple: https://podcasts.apple.com/us/podcast/history-102-with-whatifalthists-rudyard-lynch-and/id1730633913 —

In this episode, Sasha Orloff is joined by Eugene Spevakov, the Treasurer and Head of Corporate FP&A at 6sense, treasury expert, and veteran CFO. Sasha and Eugene dive deep into the Treasury function: how it differs across industries, how a scaling startup will know when it's time to hire for the role, how to structure the function, and what separates a great treasurer from merely good. Eugene offers a masterclass on leveraging treasury to drive growth, improve cash flow, and allocate risk strategically in an uncertain world.

In today's episode, Noah Smith and Erik Torenberg dive into the complexities of immigration, global economic development, and cultural stereotypes. Noah also shares insights from his upcoming book on reviving Japan's economy, examining strategies like innovation, reforming large corporations, and attracting foreign investments. --

Join Nathan for an insightful episode of The Cognitive Revolution with Wade Foster, co-founder and CEO of Zapier. Discover how this no-code pioneer is evolving into an AI-powered platform for the future of work. Learn about Zapier's ambitious vision, their integration of AI throughout their product, and how they're adapting as a company. From AI-driven lead qualification to innovative customer use cases, explore the cutting edge of automation at scale. Wade shares valuable insights on effective AI prompting, internal AI adoption strategies, and his perspective on recent AI advancements. Check out the ZapConnect 2024 event: https://zapier.com/zapconnect Apply to join over 400 Founders and Execs in the Turpentine Network: https://www.turpentinenetwork.co/ SPONSORS: WorkOS: Building an enterprise-ready SaaS app? WorkOS has got you covered with easy-to-integrate APIs for SAML, SCIM, and more. Join top startups like Vercel, Perplexity, Jasper & Webflow in powering your app with WorkOS. Enjoy a free tier for up to 1M users! Start now at https://bit.ly/WorkOS-Turpentine-Network Weights & Biases Weave: Weights & Biases Weave is a lightweight AI developer toolkit designed to simplify your LLM app development. With Weave, you can trace and debug input, metadata and output with just 2 lines of code. Make real progress on your LLM development and visit the following link to get started with Weave today: https://wandb.me/cr 80,000 Hours: 80,000 Hours offers free one-on-one career advising for Cognitive Revolution listeners aiming to tackle global challenges, especially in AI. They connect high-potential individuals with experts, opportunities, and personalized career plans to maximize positive impact. Apply for a free call at https://80000hours.org/cognitiverevolution to accelerate your career and contribute to solving pressing AI-related issues. Omneky: Omneky is an omnichannel creative generation platform that lets you launch hundreds of thousands of ad iterations that actually work customized across all platforms, with a click of a button. Omneky combines generative AI and real-time advertising data. Mention "Cog Rev" for 10% off https://www.omneky.com/ RECOMMENDED PODCAST: This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel ft their hottest takes on the future of tech, business, and venture capital. Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz CHAPTERS: (00:00:00) About the Show (00:00:22) Sponsors: WorkOS (00:01:22) About the Episode (00:03:41) Introduction and Zapier's Competitive Edge (00:07:20) AI as Knowledge Worker Companion (00:10:27) Impressive AI Use Cases (00:16:25) Sponsors: Weights & Biases Weave | 80,000 Hours (00:19:05) AI Implementation Challenges (00:19:13) LLM Performance and Prompting (00:22:42) AI Adoption within Zapier (00:31:00) Sponsors: Omneky (00:31:23) AI-Assisted Workflow Creation (00:36:07) AI Culture and Adoption at Zapier (00:43:03) AI Impact on Zapier's Productivity (00:48:06) Zapier's AI Integration Strategy (00:54:43) Outro

In this crosspost from the 80,000 Hours podcast, host Rob Wiblin interviews Nick Joseph, Head of Training at Anthropic, about the company's responsible scaling policy for AI development. The episode delves into Anthropic's approach to AI safety, the growing trend of voluntary commitments from top AI labs, and the need for public scrutiny of frontier model development. The conversation also covers AI safety career advice, with a reminder that 80,000 Hours offers free career advising sessions for listeners. Join us for an insightful discussion on the future of AI and its societal implications. Apply to join over 400 Founders and Execs in the Turpentine Network: https://www.turpentinenetwork.co/ SPONSORS: WorkOS: Building an enterprise-ready SaaS app? WorkOS has got you covered with easy-to-integrate APIs for SAML, SCIM, and more. Join top startups like Vercel, Perplexity, Jasper & Webflow in powering your app with WorkOS. Enjoy a free tier for up to 1M users! Start now at https://bit.ly/WorkOS-Turpentine-Network Weights & Biases Weave: Weights & Biases Weave is a lightweight AI developer toolkit designed to simplify your LLM app development. With Weave, you can trace and debug input, metadata and output with just 2 lines of code. Make real progress on your LLM development and visit the following link to get started with Weave today: https://wandb.me/cr 80,000 Hours: 80,000 Hours offers free one-on-one career advising for Cognitive Revolution listeners aiming to tackle global challenges, especially in AI. They connect high-potential individuals with experts, opportunities, and personalized career plans to maximize positive impact. Apply for a free call at https://80000hours.org/cognitiverevolution to accelerate your career and contribute to solving pressing AI-related issues. Omneky: Omneky is an omnichannel creative generation platform that lets you launch hundreds of thousands of ad iterations that actually work customized across all platforms, with a click of a button. Omneky combines generative AI and real-time advertising data. Mention "Cog Rev" for 10% off https://www.omneky.com/ RECOMMENDED PODCAST: This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel ft their hottest takes on the future of tech, business, and venture capital. Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz CHAPTERS: (00:00:00) About the Show (00:00:22) Sponsors: WorkOS (00:01:22) About the Episode (00:04:31) Intro and Nick's background (00:08:37) Model training and scaling laws (00:13:10) Nick's role at Anthropic (00:16:49) Responsible Scaling Policies overview (Part 1) (00:18:00) Sponsors: Weights & Biases Weave | 80,000 Hours (00:20:39) Responsible Scaling Policies overview (Part 2) (00:25:24) AI Safety Levels framework (00:30:33) Benefits of RSPs (Part 1) (00:33:15) Sponsors: Omneky (00:33:38) Benefits of RSPs (Part 2) (00:36:32) Concerns about RSPs (00:47:33) Sandbagging and evaluation challenges (00:54:46) Critiques of RSPs (01:03:11) Trust and accountability (01:12:03) Conservative vs. aggressive approaches (01:17:43) Capabilities vs. safety research (01:23:47) Working at Anthropic (01:35:14) Nick's career journey (01:45:12) Hiring at Anthropic (01:52:06) Concerns about AI capabilities work (02:03:38) Anthropic office locations (02:08:46) Pressure and stakes at Anthropic (02:18:09) Overrated and underrated AI applications (02:35:57) Closing remarks (02:38:33) Sponsors: Outro

In this thought-provoking episode, repeat guests of MOZ Hannah and Steve (both anonymous) return to debate the controversy surrounding Tucker Carlson's Martyr Made interview with historian Daryl Cooper about World War II. They critically examine Cooper's contentious views on Churchill and Hitler, discussing the dangers of historical revisionism from both the left and the right and its impact on modern political discourse. The conversation explores the fine line between challenging historical narratives and engaging in counterproductive provocation, touching on issues of antisemitism, the political alignment of Jewish Americans, and the broader implications for right-wing politics. --

This week on Upstream, we're featuring a discussion between Samo Burja, Rudyard Lynch and Erik Torenberg about the inherent differences between civilizations and their impact on history and politics. They explore the parallels and distinctions between ancient civilizations like Babylon and modern entities like Silicon Valley, the influence of Abrahamic religions, and how societal patterns challenge our current understanding.  —

In this episode of The Cognitive Revolution, Nathan explores the cutting-edge intersection of AI and biology with Stanford assistant professor Brian Hie. Discover how AI is revolutionizing our understanding of biological systems and creating new possibilities for interventions. Brian discusses his groundbreaking papers on hybrid AI architectures, the surprising capabilities of language models trained on DNA sequences, and AI-guided evolution of antibodies. Join us for an insightful journey into the future of AI in biology, touching on biosecurity, drug discovery, and the challenges of interpreting AI models in biological contexts. Links : Brian Hie : https://x.com/BrianHie Scanorama paper Mechanistic Design and Scaling of Hybrid Architectures Sequence modeling and design from molecular to genome scale with Evo Unsupervised evolution of protein and antibody complexes with a structure-informed language model Apply to join over 400 Founders and Execs in the Turpentine Network: https://www.turpentinenetwork.co/ SPONSORS: 80,000 Hours: 80,000 Hours offers free one-on-one career advising for Cognitive Revolution listeners aiming to tackle global challenges, especially in AI. They connect high-potential individuals with experts, opportunities, and personalized career plans to maximize positive impact. Apply for a free call at https://80000hours.org/cognitiverevolution to accelerate your career and contribute to solving pressing AI-related issues. Brave: The Brave search API can be used to assemble a data set to train your AI models and help with retrieval augmentation at the time of inference. All while remaining affordable with developer first pricing, integrating the Brave search API into your workflow translates to more ethical data sourcing and more human representative data sets. Try the Brave search API for free for up to 2000 queries per month at https://bit.ly/BraveTCR Omneky: Omneky is an omnichannel creative generation platform that lets you launch hundreds of thousands of ad iterations that actually work customized across all platforms, with a click of a button. Omneky combines generative AI and real-time advertising data. Mention "Cog Rev" for 10% off https://www.omneky.com/ Oracle: Oracle Cloud Infrastructure (OCI) is a single platform for your infrastructure, database, application development, and AI needs. OCI has four to eight times the bandwidth of other clouds; offers one consistent price, and nobody does data better than Oracle. If you want to do more and spend less, take a free test drive of OCI at https://oracle.com/cognitive RECOMMENDED PODCAST: This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel ft their hottest takes on the future of tech, business, and venture capital. Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz CHAPTERS: (00:00:00) About the Show (00:00:22) About the Episode (00:03:22) Introduction and Overview (00:03:55) AI for Biology: Big Picture (00:05:49) Challenges in Biology and Drug Discovery (00:08:36) Scanorama and Single Cell Transcriptomics (00:10:27) Brian's Research Identity (00:13:00) Mechanistic Design of Hybrid Architectures (00:14:52) Evo: DNA Language Model (Part 1) (00:18:10) Sponsors: 80,000 Hours | Brave (00:20:44) Evo: DNA Language Model (Part 2) (00:28:58) Gene Essentiality and Evo's Capabilities (00:29:19) Unsupervised Evolution of Protein Complexes (Part 1) (00:31:02) Sponsors: Omneky | Oracle (00:32:24) Unsupervised Evolution of Protein Complexes (Part 2) (01:10:27) Improving Antibody Binding Affinity (01:14:24) Overfitting and ARC Institute (01:18:11) Sponsors: Outro

In this episode, Sasha Orloff sits down with Camille Ricketts, former Co-Head of Marketing at Notion, Editor of First Round Review and Elon's comms manager at Tesla, to talk about the ROI of content as a growth driver. Camille, currently a partner at XYZ Venture Capital, played a key role in persuading Sasha years ago to invest in content as a revenue channel. In this episode she shares her invaluable insights from her roles at Notion, Tesla, and First Round Review. Tune in to hear Camille's compelling arguments for CEOs and VPs about the strategic value of content marketing. This is a must-listen for founders, finance leaders, and anyone eager to leverage content for growth.

In today's episode of Live Players, we're featuring a discussion between Samo Burja, Rudyard Lynch and Erik Torenberg about the inherent differences between civilizations and their impact on history and politics. They explore the parallels and distinctions between ancient civilizations like Babylon and modern entities like Silicon Valley, the influence of Abrahamic religions, and how societal patterns challenge our current understanding.  —

Erik Torenberg is joined by Noor Siddiqui, founder and CEO of Orchid, to explore groundbreaking advancements in reproductive technology, especially the world's first whole genome embryo screening. They dive into genome sequencing, IVF, and the ethical implications of these technologies, highlighting their potential to significantly reduce the incidence of major diseases. Noor shares her journey of bringing Orchid's innovative solutions from research to market, along with the importance of polygenic scores and the evolving societal views on reproductive tech.  —

In today's episode, Noah Smith and Erik Torenberg explore the complexities surrounding fracking, China's economic growth and challenges, and tackle a controversy in Springfield involving false claims about Haitian immigrants and the larger implications for U.S. immigration policy. --

In this sponsored episode of The Cognitive Revolution, Nathan interviews Andrei Oprisan, Engineering Lead at Agent.ai. They explore the cutting-edge world of AI agents and their impact on the future of work. Andrei shares insights on language model limitations, best practices for building AI agents, and Agent AI's vision as a professional network for AI agents. The conversation covers technical details like fine-tuning models, vector database choices, and privacy-preserving techniques. Don't miss this deep dive into AI's role in transforming industries and the skills needed in an AI-augmented workplace. Check out Agent.ai website here: https://agent.ai Apply to join over 400 Founders and Execs in the Turpentine Network: https://www.turpentinenetwork.co/ SPONSORS: Weights & Biases Weave: Weights & Biases Weave is a lightweight AI developer toolkit designed to simplify your LLM app development. With Weave, you can trace and debug input, metadata and output with just 2 lines of code. Make real progress on your LLM development and visit the following link to get started with Weave today: https://wandb.me/cr Oracle: Oracle Cloud Infrastructure (OCI) is a single platform for your infrastructure, database, application development, and AI needs. OCI has four to eight times the bandwidth of other clouds; offers one consistent price, and nobody does data better than Oracle. If you want to do more and spend less, take a free test drive of OCI at https://oracle.com/cognitive Brave: The Brave search API can be used to assemble a data set to train your AI models and help with retrieval augmentation at the time of inference. All while remaining affordable with developer first pricing, integrating the Brave search API into your workflow translates to more ethical data sourcing and more human representative data sets. Try the Brave search API for free for up to 2000 queries per month at https://bit.ly/BraveTCR Omneky: Omneky is an omnichannel creative generation platform that lets you launch hundreds of thousands of ad iterations that actually work customized across all platforms, with a click of a button. Omneky combines generative AI and real-time advertising data. Mention "Cog Rev" for 10% off https://www.omneky.com/ Squad: Head to Squad to access global engineering without the headache and at a fraction of the cost: head to https://choosesquad.com/ and mention “Turpentine” to skip the waitlist. RECOMMENDED PODCAST: This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel ft their hottest takes on the future of tech, business, and venture capital. Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz CHAPTERS: (00:00:00) About the Show (00:00:22) Sponsors: Weights & Biases Weave (00:01:28) About the Episode (00:05:36) Introduction and AI Agents Overview (00:07:02) Current State of AI Agents (00:11:30) Building and Optimizing AI Agents (00:19:01) Sponsors: Oracle | Brave (00:21:05) Agent.ai Platform and Marketplace (00:31:12) Sponsors: Omneky | Squad (00:32:38) Customization and Context for Agents (00:33:34) Business Model and Monetization (00:36:53) Tech Stack and Development Process (00:43:55) Future of Work and AI Impact (01:03:46) Fine-tuning and Chain of Thought (01:14:30) Capturing Human Reasoning Process (01:21:00) Preparing for Rapid AI Advancement (01:40:58) AI's Impact on Jobs and Society (02:00:16) Closing Thoughts and Future Outlook (02:03:33) Sponsors: Outro

In today's episode, Noah Smith and Brad DeLong tackle pressing topics such as the potential for a 'China Shock 2', the effectiveness of missile defense systems, and the shifting role of economists since the Great Recession. They also explore the nuances of economic theory, policy implementation, and real-world outcomes, particularly in a fast-paced information age.  --

When Y Combinator's Paul Graham released his viral essay "Founder Mode," it sparked a firestorm in the tech world. Based on a private talk by Airbnb's Brian Chesky and endorsed by the likes of Elon Musk and Patrick Collison, the piece garnered over 20 million views. Enter Jim Cook, legendary Silicon Valley CFO (Netflix, Intuit, Mozilla) who just wrote a counterargument to set the record straight. Cook challenges the simplistic notion of founder supremacy — where only 10% succeed — and offers a different Leadership Mode framework for building high-performance, generational companies.

Kaz Nejatian is Shopify's VP of Product & Chief Operating Officer. Before Shopify, Kaz founded Kash, a payment technology company which was acquired in 2017 by one of the largest fintech companies in the U.S. Kaz then served as Product Lead for Payments and Billing at Facebook, reducing the barriers for businesses in cash-dependent markets to purchase digital ads without a credit card. In Today's Episode with Kaz Nejatian We Discuss: 1. Learnings From the Greats: Mark Zuckerberg: What are Kaz's biggest lessons from working with Zuck? Why does Kaz believe Zuck is massively under-appreciated? Keith Rabois: What are Kaz's biggest lessons from working with Keith? How did it change how he operates on a day to day basis? Tobi Lütke: What have been Kaz's biggest lessons from working with Tobi? What has he changed most significantly since working with Tobi? 2. Shopify: Why We Build Our Own Tools: Why does Kaz believe it is crucial for Shopify to build their own tools? When did he doubt this strategy most? What caused him to question it? Why does Kaz believe the Stripe Shopify partnership is the most important in business? What is the role of a PM at Shopify? Why do Shopify focus on how not what product is built? 3. Eight Truths The Startup World Gets Wrong: Why does Kaz believe "The Lean Startup" has done more damage than any other startup book? Why does Kaz believe that 90% of companies do not know what they want when they hire? Why does Kaz believe the way that companies pay their staff is totally wrong? Why does Kaz believe that most companies pick fights they do not need to pick? Why does Kaz believe that for 90% of companies remote work is a terrible idea? Why does Kaz believe that everyone in sales and marketing should be able to code? Why does Kaz believe that married people with kids are more, not less productive? Why does Kaz believe that we totally misunderstand divorce rates?