Podcasts about synthesize

In this episode of Speakernomics, host Kenneth "Shark" Kinney brings together insights from 16 diverse voices within the speaking industry to explore the essential marketing materials needed for speakers to elevate their business. In this session, you will: Analyze the various perspectives on the most critical marketing tool, including the significance of a compelling demo reel and a comprehensive website. Explore the role of relationships and reputation in driving successful speaking engagements and building a thriving speaking career. Synthesize the collective wisdom from speakers, agents, and meeting planners on creating a holistic marketing strategy that emphasizes transformation over self-promotion. Speakers: Mark Sharenbroich, CSP, CPAE Karen McCullough, CSP Denise Hamilton David Stollman Lois Creamer Frank Kitchen, CSP Deia Starr Rank Mike Ganino Michelle Joyce Dennis Yu Dejah Urbanovitch Thom Singer, CSP Christa Haberstock Chris West Shannon Jones Learn more about your ad choices. Visit megaphone.fm/adchoices

Have you lost your enthusiasm for our valuation industry? Do you feel disconnected and uninspired?  Welcome to another insightful episode of Indispensable Appraisers!  In this Podcast Jeff Hicks, MAI - Founder, Realwired speaks with Brendan Wewer, MAI, - Director of Valuation & Advisory at Commonwealth Commercial Appraisal Group. Key take-a-ways from their meeting: • Absence of new creation of small and mid-sized appraisal firms. • Human connection is key – young appraisers need it. • Synthesize big data will keep appraisers relevant. • Meet the client where they're at. • Appraisers are story tellers, AI technology can become a partner. Let's start this conversation. Just call my cell 813-230-3798 or e-mail me Jeff@realwired.com.   Subscribe to our weekly blog: https://realwired.com/blog/  www.realwired.com 

There may come a time when you're unable to use your voice to communicate with those around you. Your iPhone, iPad, and Mac have an accessibility feature called Personal Voice that lets you synthesize a voice that sounds similar to you, giving you the ability to communicate with others. Mikah Sargent walks you through the process of setting up a Personal Voice and using Live Speech to access it. You can use your Personal Voice for FaceTime calls, phone calls, in specific apps, and more! Create a Personal Voice on your iPhone, iPad, or Mac - Apple Support - https://support.apple.com/en-us/104993 Use Live Speech on your iPhone, iPad, Mac, or Apple Watch - Apple Support - https://support.apple.com/en-us/105018 Host: Mikah Sargent Want access to the video version and exclusive features? Become a member of Club TWiT today! https://twit.tv/clubtwit Club TWiT members can discuss this episode and leave feedback in the Club TWiT Discord.

There may come a time when you're unable to use your voice to communicate with those around you. Your iPhone, iPad, and Mac have an accessibility feature called Personal Voice that lets you synthesize a voice that sounds similar to you, giving you the ability to communicate with others. Mikah Sargent walks you through the process of setting up a Personal Voice and using Live Speech to access it. You can use your Personal Voice for FaceTime calls, phone calls, in specific apps, and more! Create a Personal Voice on your iPhone, iPad, or Mac - Apple Support - https://support.apple.com/en-us/104993 Use Live Speech on your iPhone, iPad, Mac, or Apple Watch - Apple Support - https://support.apple.com/en-us/105018 Host: Mikah Sargent Want access to the video version and exclusive features? Become a member of Club TWiT today! https://twit.tv/clubtwit Club TWiT members can discuss this episode and leave feedback in the Club TWiT Discord.

There may come a time when you're unable to use your voice to communicate with those around you. Your iPhone, iPad, and Mac have an accessibility feature called Personal Voice that lets you synthesize a voice that sounds similar to you, giving you the ability to communicate with others. Mikah Sargent walks you through the process of setting up a Personal Voice and using Live Speech to access it. You can use your Personal Voice for FaceTime calls, phone calls, in specific apps, and more! Create a Personal Voice on your iPhone, iPad, or Mac - Apple Support - https://support.apple.com/en-us/104993 Use Live Speech on your iPhone, iPad, Mac, or Apple Watch - Apple Support - https://support.apple.com/en-us/105018 Host: Mikah Sargent Want access to the video version and exclusive features? Become a member of Club TWiT today! https://twit.tv/clubtwit Club TWiT members can discuss this episode and leave feedback in the Club TWiT Discord.

Welcome to the deep dive discussion of the West Coast Sports podcast featuring the remarkable Dodgers, Lakers, and Raiders games of recent. Assess their game performance, dissect in-depth strategies, and uncover potential moves. Join the intriguing analysis on the Lakers' performance against Denver Nuggets. Explore their strategic approach, strengths, weaknesses, and the dynamics that led to an unexpected outcome in the fourth quarter. Insights into the upcoming opportunities for the Lakers are also discussed, with the potential of recovering players returning to the court in view. Synthesize the performance of Dodgers against the Nationals. Understand how they have been revamping their offense, making monster home runs, and extending their success streak. Review their determined strategy to win against formidable opponents and how they're strategizing for victory. Dive into the conversation on the Raiders and their potential moves in the draft, including the possible securing of a rookie quarterback. The analysis presents a range of options they face and the potential benefits and drawbacks of each decision. The podcast brings the thrill of the game to you, offering insights into potential tactical shifts, key players, and uncertain times due to existing injuries. As you feel the heat of competition and the grit of determination, anticipate some new and strong faces on the field. Don't miss out on the excitement of these sports narratives.

What do you want your audience to understand about your brand? Ask this question with every piece of content you create. Because you want to drive home a specific message. If it's not doing the job, you need to synthesize the information for your audience. Distill your message to show the value and benefits of your product. It's how you cut through the noise and capture the attention of your audience. That's what we're talking about today with the help of Sproutloud's Director of Demand Generation, Aaron Morrissey. Together, we watch Parts Unknown and chat about lessons we can take from Anthony Bourdain, including being yourself in your content and synthesizing your message. About our guest, Aaron MorrisseyAaron Morrissey is the Director of Demand Generation at Sproutloud Media Networks, where he works with enterprise clients to help them launch, manage, and optimize digital campaigns across their distributed network. He joined the company in November of 2022. Prior to his current role, he served as Director of Demand Gen at Topia. He is also a content creator for HockeyStack and other B2B SaaS brands.What B2B Companies Can Learn From Parts Unknown:Be the same person in your content as you are in real life. Show that there's a real person behind the content you're creating, not some corporate bot. So breathe personality and soul into your content. Aaron says, “When the cameras turned on from when the cameras turned off, [Anthony Bourdain] was the same person. If I'm the same person all around, people will start to either  gravitate toward that or realize that I'm not their cup of tea. People talk so much about authenticity. The real authenticity is truly not being afraid of the consequences of being yourself.” Synthesize your message to drive home the point you're making. Supplement the visuals with a carefully crafted narrative in your voice that explains what you want your audience to understand. Ian says, “[Anthony Bourdain] brings you into a world that you don't know anything about. And he's giving you these visuals and these conversations. But then he's also synthesizing the information for you in an extremely tight narrative so that he's hammering home the point of what you're seeing with a very clear lesson in every episode. It's what makes it so brilliant.”Time Stamps[0:55] Meet Aaron Morrissey, Director of Demand Generation at Sproutloud[1:47] Exploring the Uncompromising Creativity of Parts Unknown[5:36] Aaron Morrissey's Journey: From Content Creation to Demand Generation[7:47] The Essence and Impact of Anthony Bourdain's Parts Unknown[15:22] Crafting a Personal Brand: Insights from Anthony Bourdain's Legacy[19:24] The Art of Content Creation: Learning from Bourdain's Approach[21:09] Synthesizing Information: The Key to Engaging Content[24:45] Exploring Culinary Delights and Conversational Skills[25:35] The Art of Storytelling in Parts Unknown[27:12] Anthony Bourdain's Legacy and the Power of Serialized Content[28:18] The Impact of Following Bourdain's Footsteps[30:35] Creative Evolution and the Importance of Authenticity[36:49] Marketing Strategies and the Future of Content Creation[47:06] Predictions on the Future of the Creator World and B2B ContentLinksWatch Parts UnknownConnect with Aaron on LinkedInLearn more about SproutloudAbout Remarkable!Remarkable! is created by the team at Caspian Studios, the premier B2B Podcast-as-a-Service company. Caspian creates both non-fiction and fiction series for B2B companies. If you want a fiction series check out our new offering - The Business Thriller - Hollywood style storytelling for B2B. Learn more at CaspianStudios.com. In today's episode, you heard from Ian Faison (CEO of Caspian Studios) and Meredith Gooderham (Senior Producer). Remarkable was produced this week by Jess Avellino, mixed by Scott Goodrich, and our theme song is “Solomon” by FALAK. Create something remarkable. Rise above the noise.

In this episode, Sope Agbelusi explores the power of silence and the importance of pausing in personal growth and leadership. Silence is described as the canvas of thought, providing a space for reflection, insights, and innovative thinking. The episode emphasizes the discomfort of silence in a world that never stops talking and encourages listeners to embrace the pause as a tool for clarity, creativity, and connection. The transformative potential of the pause is illustrated through personal stories and examples from organizations like Microsoft. The episode concludes with a reminder that our growth and freedom lie in the space between stimulus and response.TakeawaysSilence as the Canvas of ThoughtThe Power of the PauseClarity, Creativity, and ConnectionConfronting Challenges in the PausePersonal Transformation in the PauseThe Power of the Pause in LeadershipMaking the Power of the Pause PracticalThe Process of Pausing: Perceive, Acknowledge, Understand, Synthesize, EvaluateChoosing Our ResponseConnect with MeWebsite |Youtube |Instagram |LinkedInEmail: hello@mindsetshift.co.uk

• The Nitecaps • The Rookies • El Último Vecino • Los Iniciados • Essential Tremors • Cherrelle • Vhyce • DMX Krew • The Veldt • Lion • The Space Lady

Support the show to get full episodes and join the Discord community. Peter Stratton is a research scientist at Queensland University of Technology. I was pointed toward Pete by a patreon supporter, who sent me a sort of perspective piece Pete wrote that is the main focus of our conversation, although we also talk about some of his work in particular - for example, he works with spiking neural networks, like my last guest, Dan Goodman. What Pete argues for is what he calls a sideways-in approach. So a bottom-up approach is to build things like we find them in the brain, put them together, and voila, we'll get cognition. A top-down approach, the current approach in AI, is to train a system to perform a task, give it some algorithms to run, and fiddle with the architecture and lower level details until you pass your favorite benchmark test. Pete is focused more on the principles of computation brains employ that current AI doesn't. If you're familiar with David Marr, this is akin to his so-called "algorithmic level", but it's between that and the "implementation level", I'd say. Because Pete is focused on the synthesis of different kinds of brain operations - how they intermingle to perform computations and produce emergent properties. So he thinks more like a systems neuroscientist in that respect. Figuring that out is figuring out how to make better AI, Pete says. So we discuss a handful of those principles, all through the lens of how challenging a task it is to synthesize multiple principles into a coherent functioning whole (as opposed to a collection of parts). Buy, hey, evolution did it, so I'm sure we can, too, right? Peter's website. Related papers Convolutionary, Evolutionary, and Revolutionary: What's Next for Brains, Bodies, and AI? Making a Spiking Net Work: Robust brain-like unsupervised machine learning. Global segregation of cortical activity and metastable dynamics. Unlocking neural complexity with a robotic key 0:00 - Intro 3:50 - AI background, neuroscience principles 8:00 - Overall view of modern AI 14:14 - Moravec's paradox and robotics 20:50 -Understanding movement to understand cognition 30:01 - How close are we to understanding brains/minds? 32:17 - Pete's goal 34:43 - Principles from neuroscience to build AI 42:39 - Levels of abstraction and implementation 49:57 - Mental disorders and robustness 55:58 - Function vs. implementation 1:04:04 - Spiking networks 1:07:57 - The roadmap 1:19:10 - AGI 1:23:48 - The terms AGI and AI 1:26:12 - Consciousness

Synthesize these factors into your spiritual, scriptural service with amazing results.

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Welcome to the CRO Spotlight Podcast! In today's episode we delve into a thought-provoking conversation between Warren Zena, CEO of the CRO Collective, and Julia Nimchinski, founder of Hype Cycle and the Hard skill Exchange. The discussion centers around the vital role of chief revenue officers (CROs) in integrating sales, marketing, and customer success functions within businesses. Together, they explore the challenges of hyperbolic growth, the impact on customer neglect, and the necessity for collaboration across various departments to foster innovation and customer-driven organizations. Get ready to explore the evolving landscape of business ecosystems, the importance of knowledge-sharing platforms, and the value of practical learning in today's competitive market. This episode promises to inspire and equip you with valuable insights for scaling your business in a rapidly changing world.00:00 Balance sales, marketing, customer success for success.06:29 TV show "Super Pumped" exposes economic manipulation.08:54 Focus on real need, niche markets grow.12:58 Inspiring Airbnb story emphasizes effective marketing communication.15:18 Emphasize customer relationship over purely product-focused approach.20:18 Understanding others' expertise for improved productivity.21:59 Community progress, innovation, monetizing expertise, industry challenges.24:45 Summary: GTM MAG simplifies go-to-market skill building.29:32 Called professor to arbitrate dinner vs supper.32:50 Fascination with the human mind and selling.34:28 Synthesize ideas, talk, adapt, embrace AI for success.37:42 Roger respected and empowered through positive leadership.40:33 Every project involves going to market.

Every brand gets its power from connecting with people and delivering on its promises. And that starts with internal branding. I'm taking inspiration from a conversation I had with David and Sam, where we emphasize internal branding: taking an internal focus before taking your brand identity to the world. We'll explore why internal branding should be your first focus, the pitfalls of neglecting it, and how to implement it successfully within your team. By aligning your internal stakeholders first, you set the stage for a more cohesive and powerful brand presence in the market. https://youtu.be/hlG0ojbxGo0 Focus on Your Team First Nobody advocates for your brand like employees. Their words and actions tell everyone what your brand stands for. If they know your brand—and you hire well, based on your brand—your employees will see the connection. And that consistent brand experience—through the words and actions of your employees—connects with customers more than your claims ever will. Create clear guidance and your employees will give you a cohesive internal brand that enhances customer service, employee satisfaction, and overall business performance. Not Convinced Internal Branding Matters? Here's what happens when external branding fails to connect with your employees. Lack of Cohesion. Without internal branding, your team acts and speaks inconsistently, confusing clients. Employee Disengagement. When employees don't feel connected to the brand, their engagement and productivity suffer. Reputation Risks. Inconsistent branding can damage your reputation, making it harder to attract both clients and talent. Missed Opportunities. A team that's not aligned with the brand won't know how to represent the firm in social settings or online platforms. Neglecting internal branding can have real financial consequences, from lost sales to increased employee turnover. The Overview: Implement Internal Branding Branding starts at the top but doesn't stay there. We've all seen companies that embrace amazing-sounding values but don't live up to them. You might be at the counter at the car rental desk, and you can't get the agent to live up to their own values. The values are literally on the wall behind the person helping you. They're just not lived out. So how do you build out those brand values properly and honestly? Start with Leadership. The first step in internal branding is getting buy-in from the top. Leadership needs to exemplify the brand values. Synthesize. People grow in understanding when they're asked to think through the brand regularly. Ask everyone to apply them to a situation that happened recently. Did they live up to them? Is there room for improvement? Make sure everyone understands the brand's values, mission, and vision. Give them Guides. Don't give them long paragraphs to read. Give them workshops, handbooks, or even regular internal communications. Know the Tools for Internal Branding Internal branding uses different tools than external. But they all do the same thing in the end: instill an understanding of the brand to humans who can either be encouraged and excited about values or eventually forget. Here are some ways you can keep everyone engaged internally. Brand Handbook & Workshops: Combine a comprehensive guide with internal training sessions to educate team members on brand elements, values, and practical applications. Digital Communication: Use platforms like Slack or Microsoft Teams for consistent, brand-aligned messaging and updates. Employee Engagement: Implement regular surveys and distribute high-quality branded merchandise to assess and reinforce brand understanding within the team. Prioritize the Launch Employees get engaged when they see the commitment from the firm's leadership. The most obvious way to do this is through a brand launch event. However you do it, make sure you launch in a very visible way that involve...

In this episode, we will explore the concept of happiness, why people often chase it, and the phenomenon known as the hedonic treadmill. We will discuss the potential pitfalls of constantly seeking happiness and offer strategies for finding contentment in life. Don't forget to sign up for our newsletter to stay updated on future content that will empower you to create a happier and more fulfilling lifestyle. Subscribe at www.beyourownkind.com. Subscribe to our Media Partner's Youtube: https://www.thebpmediaco.com/ Support Mommy's Business: CBS3 Designs: https://www.etsy.com/shop/CBS3Designs?ref=shop_sugg_market Seeking Therapy? Get 10% off your first month at https://betterhelp.com/byok 00:00:00 Introduction 00:02:13 Sunshine: Swanky's Affirmation 00:05:17 Sunshine: Diddy has a Change of Heart 00:07:54 Sunshine: Queen Bey in her Zone 00:09:00 AD: #THEBLUEPRINTMEDIALIVE 00:10:17 Kee w/ Ree: What Random Thing Gives You Anxiety? 00:12:39 Kee w/ Ree: Neiman Marcus Broke? 00:14:10 Kee w/ Ree: Bodily Fluids Re-routing Flight 00:17:51 AD: #BYOKPLATFORM 00:19:31 BYOK FIRST EVENT!!! 00:22:00 What's the 411?: Woman Attacked by Not Giving Her Number 00:25:02 What's the 411?: Justice for Ta'Kiya Young 00:29:48 What's the 411? The Mayor of Chicago First 100 days 00:36:10 What's the 411?: VP Kamala Ready to Step in If Need Be 00:40:15 AD: #BETTERHELP 00:42:41 Feature Topic: Are We Chasing Happiness? 00:44:50 Feature Topic: Hedonic Treadmill 00:47:49 Feature Topic: Mommy is having a problem with the word Chase 00:52:33 Feature Topic: Hedonic Treadmill Pt. 2 00:54:10 Feature Topic: Synthesizing Happiness 00:57:38 Feature Topic: Defining the Word "Chase" 00:59:01 Feature Topic: Defining the Work "Synthesize" 01:05:18 Outro --- Send in a voice message: https://podcasters.spotify.com/pod/show/beyourownkind/message Support this podcast: https://podcasters.spotify.com/pod/show/beyourownkind/support

__ [Mol Neurobiol] 2020 Jun; Vol. 57 (6), pp. 2654-2670 Oncol Rep. 2023 May;49(5):93 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Christian ministries often spend significant amounts of money on conferences, marketing, and other things that can seem excessive. Do such expenses align with a wartime lifestyle?This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/3279340/advertisement

Christian ministries often spend significant amounts of money on conferences, marketing, and other things that can seem excessive. Do such expenses align with a wartime lifestyle?

Question: What cofactors are needed to synthesize and recycle BH4? Short Answer: Zinc, magnesium, potassium, and niacin are the cofactors needed for the synthesis and recycling of BH4. Folate and methylation are not involved, though high-dose folate or folic acid could hypothetically hurt BH4 recycling since both are recycled by dihydrofolate reductase (DHFR). This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link: https://chrismasterjohnphd.substack.com/p/questions-on-vitamin-d-sulfate-synthesis In that batch of free episodes you will also find the answers to these questions: Is It Important to Get Vitamin D Sulfate Specifically From the Sun? How Much Iron Can We Absorb At Once? If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up: https://chrismasterjohnphd.substack.com/qanda Learn more about the Masterpass here: https://chrismasterjohnphd.substack.com/about This snippet is from the February 15, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what's included: Is It Important to Get Vitamin D Sulfate Specifically From the Sun? How Much Iron Can We Absorb At Once? What nutrients are important for long-term PPI use? For how long does transferrin saturation respond to recent iron-rich food? Muscle spasms: creatine, creatinine, sodium, and potassium. Hematologists ignore iron saturation. How to detox arsenic? Could folic acid supplements impair BH4 recycling? How to increase butyrate? More on hematologists and transferrin saturation. Here's a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-february  Access the show notes, transcript, and comments here.

Three university faculty began a quest to reform teaching and learning at their institution. The result was a three-legged stool which has proven to be a powerful tool in faculty and curriculum development at all educational levels.

Three university faculty began a quest to reform teaching and learning at their institution. The result was a three-legged stool which has proven to be a powerful tool in faculty and curriculum development at all educational levels.

The weather is heating up, and so are the tunes, with new music on Hospital Records, Liquicity, Fokuz, onesevenfour, Goldfat, and more!Tracklist:Gemma Rose, Sorn, & Inigma – Yours [DNBB]T & Sugah – Let Me Out ft. Karina Ramage (BCee Remix) [Liquicity]Pyxis – Truly Madly Deeply [Goldfat]Artsea- Gel Balls [onesevenfour]Cnof – City Rhythm [Forthcoming Fokuz]SundayGrooves – Knowing [Influenza]Operator Unknown & Leo Wood – Feel It [Galacy]Wez Walker – Through The Glass [Mathematica]Alkali – Out Of Love [Forthcoming Fokuz]Dan Guidance – First Love [Flight Pattern]London Elektricity – Fast Soul Music ft. Liane Carrol (Dogger & Mindstate Remix) [Hospital]London Elektricity – Born to Synthesize ft. Liane Carrol (Bop & Subwave Remix) [Hospital]Digital Native – Been Ages Since [Goldfat]Drum Origins – Brave [Influenza]DPR – Night & Day [Forthcoming Fokuz]

00:00 Champions of the Continent 01:37 Chairs, Yes, Chairs 03:52 Zelda: Tears of the Kingdom & Jedi: Survivor 14:54 Lemon "Juice" 25:45 Marvel Snap 45:35 Disney+ & Willow

What Got You There with Sean DeLaney Podcast Notes Key Takeaways Understand the difference between work and play: work is anything that is energy-depleting, while play is energy-regeneratingIn life, there is a big difference between what you are good at and how you are wiredIf you do not love what you do, you will probably not stick with it even if you excel at itNo amount of pleasure from lifestyle inflation can offset a lack of purposeWhat minimalism is to your things, slow living is to your timeConcepts of intentional living include voluntary simplicity, downshifting, minimalism, digital minimalism, decluttering, financial independence, and lifestyle design   Epiphanies happen when you read something that you intuitively knew, but aren't unable to put into words until then Always consider the second and third-order effects of an action, and try to make that action positively reinforce other goals that you haveAs you psychologically develop, how you relate to what you know changesQuality is a byproduct of quantity; you will get better at something the more that you do it A synthesizing mind is a mind with the capacity to take in a lot of information, reflect on it, and then organize it in a way that is useful to you that also proves useful to othersWhen you reflect on a situation or period of time, oftentimes you realize things that you did not realize when you were in the midst of itHaving awareness of your thoughts and understanding that you are not your thoughts changes your relationship with themRead the full notes @ podcastnotes.orgKyle Kowalski is the Funder of Sloww.co (one of my favorite websites for synthesized knowledge + wisdom!)  Kyle is an ex-marketing executive turned corporate dropout and solopreneur who found and created his life purpose after an existential crisis. In one sentence, his purpose is synthesizing lifelong learning that catalyzes human development (LFG!!!).   In a nutshell, Kyle is learning why and how to live and publicly sharing what he learns along the way at Sloww.co. Thinking is his passion—but he's not a professor, philosopher, psychologist, sociologist, anthropologist, scientist, or guru. He's an interdisciplinary dot connector across all those humans and many more. Kyle does all the homework—researching, curating, reading, note-taking, summarizing, synthesizing, writing, creating, and sharing. You get all the highlights—so you spend less time on all those things and more time learning, practicing, and mastering.   About Sloww: Sloww shares the art of living with students of life. Sloww currently has a Premium membership with 1,000+ global members, a weekly email newsletter with 10,000+ subscribers, a social media following of 30,000+, and a website with 60,000+ monthly visitors (5,000,000+ lifetime pageviews).   Kyle's 10 Most Life Changing Ideas  Ikigai 2.0 Guidebook   Watch on YouTube About Host Sean DeLaney: For the last 15 years Sean DeLaney has been working at the intersection of elite performance, entrepreneurship and personal development. As an executive life coach, former professional athlete, entrepreneur, investor and podcast host Sean has been helping people discover their untapped potential and live their best life. He has been an advisor to INC. fastest growing companies, has interviewed billionaire business titans and personally coached CEO's and executives. Interested in having Sean coach you? CLICK HERE I've studied hundreds of the world's must successful people and compiled:13 Insights from the World's Most Successful People – Click Here to get access  https://youunleashedcourse.com/ You Unleashed is an online personal development course created by Sean DeLaney after spending years working with and interviewing high achievers.The online course that helps you ‘Unleash your potential'! You Unleashed teaches you the MINDSETS, ROUTINES and BEHAVIORS you need to unleash your potential and discover what you're capable of. You know you're capable of more and want to bring out that untapped potential inside of you. We teach you how. Enroll Today!- Click Here Subscribe to my Momentum Monday Newsletter Connect with us! Whatgotyouthere TikTok YouTube Twitter Instagram 

What Got You There with Sean DeLaney: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Kyle Kowalski is the Funder of Sloww.co (one of my favorite websites for synthesized knowledge + wisdom!)  Kyle is an ex-marketing executive turned corporate dropout and solopreneur who found and created his life purpose after an existential crisis. In one sentence, his purpose is synthesizing lifelong learning that catalyzes human development (LFG!!!).   In a nutshell, Kyle is learning why and how to live and publicly sharing what he learns along the way at Sloww.co. Thinking is his passion—but he's not a professor, philosopher, psychologist, sociologist, anthropologist, scientist, or guru. He's an interdisciplinary dot connector across all those humans and many more. Kyle does all the homework—researching, curating, reading, note-taking, summarizing, synthesizing, writing, creating, and sharing. You get all the highlights—so you spend less time on all those things and more time learning, practicing, and mastering.   About Sloww: Sloww shares the art of living with students of life. Sloww currently has a Premium membership with 1,000+ global members, a weekly email newsletter with 10,000+ subscribers, a social media following of 30,000+, and a website with 60,000+ monthly visitors (5,000,000+ lifetime pageviews).   Kyle's 10 Most Life Changing Ideas  Ikigai 2.0 Guidebook   Watch on YouTube About Host Sean DeLaney: For the last 15 years Sean DeLaney has been working at the intersection of elite performance, entrepreneurship and personal development. As an executive life coach, former professional athlete, entrepreneur, investor and podcast host Sean has been helping people discover their untapped potential and live their best life. He has been an advisor to INC. fastest growing companies, has interviewed billionaire business titans and personally coached CEO's and executives. Interested in having Sean coach you? CLICK HERE I've studied hundreds of the world's must successful people and compiled:13 Insights from the World's Most Successful People – Click Here to get access  https://youunleashedcourse.com/ You Unleashed is an online personal development course created by Sean DeLaney after spending years working with and interviewing high achievers.The online course that helps you ‘Unleash your potential'! You Unleashed teaches you the MINDSETS, ROUTINES and BEHAVIORS you need to unleash your potential and discover what you're capable of. You know you're capable of more and want to bring out that untapped potential inside of you. We teach you how. Enroll Today!- Click Here Subscribe to my Momentum Monday Newsletter Connect with us! Whatgotyouthere TikTok YouTube Twitter Instagram 

What Got You There with Sean DeLaney Podcast Notes Key Takeaways Understand the difference between work and play: work is anything that is energy-depleting, while play is energy-regeneratingIn life, there is a big difference between what you are good at and how you are wiredIf you do not love what you do, you will probably not stick with it even if you excel at itNo amount of pleasure from lifestyle inflation can offset a lack of purposeWhat minimalism is to your things, slow living is to your timeConcepts of intentional living include voluntary simplicity, downshifting, minimalism, digital minimalism, decluttering, financial independence, and lifestyle design   Epiphanies happen when you read something that you intuitively knew, but aren't unable to put into words until then Always consider the second and third-order effects of an action, and try to make that action positively reinforce other goals that you haveAs you psychologically develop, how you relate to what you know changesQuality is a byproduct of quantity; you will get better at something the more that you do it A synthesizing mind is a mind with the capacity to take in a lot of information, reflect on it, and then organize it in a way that is useful to you that also proves useful to othersWhen you reflect on a situation or period of time, oftentimes you realize things that you did not realize when you were in the midst of itHaving awareness of your thoughts and understanding that you are not your thoughts changes your relationship with themRead the full notes @ podcastnotes.orgKyle Kowalski is the Funder of Sloww.co (one of my favorite websites for synthesized knowledge + wisdom!)  Kyle is an ex-marketing executive turned corporate dropout and solopreneur who found and created his life purpose after an existential crisis. In one sentence, his purpose is synthesizing lifelong learning that catalyzes human development (LFG!!!).   In a nutshell, Kyle is learning why and how to live and publicly sharing what he learns along the way at Sloww.co. Thinking is his passion—but he's not a professor, philosopher, psychologist, sociologist, anthropologist, scientist, or guru. He's an interdisciplinary dot connector across all those humans and many more. Kyle does all the homework—researching, curating, reading, note-taking, summarizing, synthesizing, writing, creating, and sharing. You get all the highlights—so you spend less time on all those things and more time learning, practicing, and mastering.   About Sloww: Sloww shares the art of living with students of life. Sloww currently has a Premium membership with 1,000+ global members, a weekly email newsletter with 10,000+ subscribers, a social media following of 30,000+, and a website with 60,000+ monthly visitors (5,000,000+ lifetime pageviews).   Kyle's 10 Most Life Changing Ideas  Ikigai 2.0 Guidebook   Watch on YouTube About Host Sean DeLaney: For the last 15 years Sean DeLaney has been working at the intersection of elite performance, entrepreneurship and personal development. As an executive life coach, former professional athlete, entrepreneur, investor and podcast host Sean has been helping people discover their untapped potential and live their best life. He has been an advisor to INC. fastest growing companies, has interviewed billionaire business titans and personally coached CEO's and executives. Interested in having Sean coach you? CLICK HERE I've studied hundreds of the world's must successful people and compiled:13 Insights from the World's Most Successful People – Click Here to get access  https://youunleashedcourse.com/ You Unleashed is an online personal development course created by Sean DeLaney after spending years working with and interviewing high achievers.The online course that helps you ‘Unleash your potential'! You Unleashed teaches you the MINDSETS, ROUTINES and BEHAVIORS you need to unleash your potential and discover what you're capable of. You know you're capable of more and want to bring out that untapped potential inside of you. We teach you how. Enroll Today!- Click Here Subscribe to my Momentum Monday Newsletter Connect with us! Whatgotyouthere TikTok YouTube Twitter Instagram 

This week, we welcome Lipika Ramaswamy, Senior Applied Scientist at Gretel AI, a privacy tech company that makes it simple to generate anonymized and safe synthetic data via APIs. Previously, Lipika worked as a Data Scientist at LeapYear Technologies, and was the Machine Learning Researcher at Harvard University's Privacy Tools Project.Lipika's interest in both machine learning and privacy comes from her love of math and things that can be defined with equations. Her interest was piqued in grad school and accidentally walked into a classroom holding a lecture on Applying Differential Privacy for Data Science. The intersection of data combined with the privacy guarantees that we have available today has kept her hooked ever since.---------Thank you to our sponsor, Privado, the developer-friendly privacy platform---------There's a lot to unpack when it comes to synthetic data & privacy guarantees, as she takes listeners on a deep dive of these compelling topics. Lipika finds elegant how privacy assurances like differential privacy revolve around math and statistics at their core. Essentially, she loves building things with 'usable privacy' & security that people can easily use. We also delve into the metrics tracked in the Gretel Synthetic Data Report, which assesses both 'statistical integrity' & 'privacy levels' of a customer's training data.Topics Covered:The definition of 'synthetic data,' & good use casesThe process of creating synthetic dataHow to ensure that synthetic data is 'privacy-preserving'Privacy problems that may arise from overtraining ML modelsWhen to use synthetic data rather than other techniques like tokenization, anonymization, aggregation & othersExamples of good use cases vs poor use cases for using synthetic dataCommon misperceptions around synthetic dataGretel.ai's approach to 'privacy assurance,' including a focus on 'privacy filters,' which prevent some privacy harms outputted by LLMsHow to plug into the 'synthetic data' communityWho bears the responsibility for educating the public about new technology like LLMs and potential harmsHighlights from Gretel.ai's Synthesize 2023 conferenceResources Mentioned:Join Gretel's Synthetic Data Community on DiscordWatch Talks on Synthetic Data on YouTubeGuest Info:Connect with Lipika on LinkedIn Privado.ai Privacy assurance at the speed of product development. Get instant visibility w/ privacy code scans.Shifting Privacy Left Media Where privacy engineers gather, share, & learnBuzzsprout - Launch your podcast Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Copyright © 2022 - 2024 Principled LLC. All rights reserved.

Kyle Kowalski is the Funder of Sloww.co (one of my favorite websites for synthesized knowledge + wisdom!)  Kyle is an ex-marketing executive turned corporate dropout and solopreneur who found and created his life purpose after an existential crisis. In one sentence, his purpose is synthesizing lifelong learning that catalyzes human development (LFG!!!).   In a nutshell, Kyle is learning why and how to live and publicly sharing what he learns along the way at Sloww.co. Thinking is his passion—but he's not a professor, philosopher, psychologist, sociologist, anthropologist, scientist, or guru. He's an interdisciplinary dot connector across all those humans and many more. Kyle does all the homework—researching, curating, reading, note-taking, summarizing, synthesizing, writing, creating, and sharing. You get all the highlights—so you spend less time on all those things and more time learning, practicing, and mastering.   About Sloww: Sloww shares the art of living with students of life. Sloww currently has a Premium membership with 1,000+ global members, a weekly email newsletter with 10,000+ subscribers, a social media following of 30,000+, and a website with 60,000+ monthly visitors (5,000,000+ lifetime pageviews).   Kyle's 10 Most Life Changing Ideas  Ikigai 2.0 Guidebook   Watch on YouTube JOIN ME for 2 LIVE VIRTUAL EVENTS!  Live Podcast with David Senra, Host of Founders Podcast on March 15th at 2pm ET! Register HERE, spots are limited and even if you can't attend live if you register you'll receive a video of the interview & Q&A! “10 Mindsets to Radically Transform Your Life” Webinar on March 23rd at 1pm ET! Register HERE to learn the 10 most impactful mindsets I've uncovered working with and learning from the world's most successful people! I've studied hundreds of the world's must successful people and compiled:13 Insights from the World's Most Successful People – Click Here to get access  https://youunleashedcourse.com/ You Unleashed is an online personal development course created by Sean DeLaney after spending years working with and interviewing high achievers.The online course that helps you ‘Unleash your potential'! You Unleashed teaches you the MINDSETS, ROUTINES and BEHAVIORS you need to unleash your potential and discover what you're capable of. You know you're capable of more and want to bring out that untapped potential inside of you. We teach you how. Enroll Today!- Click Here Subscribe to my Momentum Monday Newsletter Connect with us! Whatgotyouthere TikTok YouTube Twitter Instagram 

Andrew Kirby is a YouTuber who founded Synthesizer School, a free community for educational content creators and consultants to reach financial freedom through synthesizing.In this episode of Creators On Air, Andrew shares the mindset shift from consumer to creator, a framework to build a business, and how to bring value to your audience.Follow Andrew:

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

Go online to PeerView.com/YEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of bladder cancer has undergone a significant transformation with the addition of immune checkpoint inhibitors to the treatment armamentarium. In addition, the research on actionable targets has led to regulatory approval of the FGFR-targeted therapy, erdafitinib, for FGFR mutation–positive bladder tumors, as well as the antibody–drug conjugates enfortumab vedotin and sacituzumab govitecan. Further, novel bladder preservation opportunities and important combination approaches expand the therapeutic capacity across the disease spectrum available to patients with bladder cancer. In this PeerView activity, a panel of leading bladder cancer experts pairs important analyses of the latest evidence on a new generation of therapeutics with practical insights that can be used to guide therapeutic decision-making in the clinic. This CME/MOC-certified activity will highlight strategies for optimal care of patients with bladder cancer in light of current evidence on and indications for the use of immune, targeted, and antibody-based therapies and guidance on safely integrating these agents into treatment plans. Using patient cases drawn from clinical practice and interactivity that allows participants to see how their treatment choices compare with their colleagues, the faculty will address the mechanistic rationale for these new therapies, therapeutic decision-making, and AE mitigation strategies. Upon completion of this activity, participants should be better able to: Synthesize new evidence on multi-faceted strategies for bladder cancer management based on modern immunotherapeutic agents, small molecule targeted therapies, and antibody–drug conjugates, among others; Integrate novel and emerging therapeutic approaches into personalized treatment plans for patients with bladder cancer, considering the available evidence, current guidelines, and principles of multidisciplinary and patient-centered care; and Implement evidence- and team-based management protocols to address the unique suite of adverse events associated with novel therapeutics for bladder cancer

This has been an amazing year for the show, and I'm so grateful for everybody who has listened. I'm off the last two weeks of the year but I wanted to keep something in your feed over the holidays, so this week I'm reboosting one of our most popular episodes of the year. Maybe you listened and want to listen again. Maybe you missed this one, and want to check it out. Or you're looking at this feed for the first time and trying to figure out whether this is your kind of show. I think these episodes offer a great snapshot of what we try to do here on 'Plain English.' Range widely across topics. Synthesize complicated ideas. Frame breaking news and big ideas in ways that you'll remember when the show is over. And do it all relatively quickly. No BS. No filler. An espresso shot of news analysis. In today's episode, I talk with the author Chuck Klosterman about why society has gotten so negative, ranging from TV and film to politics and social media. Maybe the most wide-ranging conversation of the year and, in terms of online reception, probably the single episode that I got the most positive feedback from … Ironically. I hope you enjoy! Happy holidays, and if you feel like giving this show a small gift, head to Spotify or Apple Podcasts and leave a five-star rating and review. It goes a long way. See you in the new year! Host: Derek Thompson Guest: Chuck Klosterman Producer: Devon Manze Learn more about your ad choices. Visit podcastchoices.com/adchoices

This has been an amazing year for the show, and I'm so grateful for everybody who has listened. I'm off the last two weeks, but I wanted to keep something in your feed over the holidays, so this week I'm re-boosting one of our most popular episodes of the year. Maybe you listened and want to listen again. Maybe you missed this one and want to check it out. Or you're looking at this feed for the first time and trying to figure out if this is your kind of show. I think these episodes offer a great snapshot of what we try to do here on 'Plain English.' Range widely across topics. Synthesize complicated ideas. Frame breaking news and big ideas in ways that you'll remember when the show is over. And do it all relatively quickly. No BS. No filler. An espresso shot of news analysis. In today's episode, I talk with The Ringer's Ryen Russillo about the most impressive sports statistic of all time. This is of course wildly subjective. And that's the fun of it. Happy holidays, and if you feel like giving this show a small gift, head to Spotify or Apple Podcasts and leave a five-star rating and review. It goes a long way. See you in the new year! Host: Derek Thompson Guest: Ryen Russillo Producer: Devon Manze Learn more about your ad choices. Visit podcastchoices.com/adchoices

What practical steps can you take to discover and uncover the man you are capable of being, and actually start living at your very best? As the year comes to a close it is time to take action, and if you are already doing that, time to step it up a gear. Let's take a deeper look at the impact that organising your environment, minimising your consumption, optimising your action, analysing your ethos or code of honor regularly and synthesising all these aspects can have on our lives if we commit to the process and remain consistent. My bet is that the impact will be so significant you won't recognise the man in the mirror before long.

Vic Clesceri is a uniquely well-rounded business leader, and we talk about helping people and companies to grow, by aligning corporate strategy and workforce strategy, by synthesizing both while translating confusing terminology into simple concepts people can rally around. 3:15 - “Strategy is a set of choices about winning.” - quoting A.G. Laffley, former CEO of Procter & Gamble 5:03 - “Do we need to upskill…reskill… or hire for skill?” 5:15 - quoting a 2020 McKinsey study “87% of (executives) state they're going to have skill gap deficiencies…about a third of them have identified this talent risk… as a top three priority…but less than half of them actually have a clear sense of vision how they're going to close that gap.” 10:18 - “Know who your audience is, and what type of language is going to resonate with those stakeholders.” 12:31 - “Those are the five steps, and when you simplify it in that type of language, everybody gets it.” - 13:30 - “Boiling it down to the essential: Who are we? Where do we want to win? How do we want to win? Current state? Future state?” 20:13 - “Leadership is all about turning a vision into reality and producing results. But it is only through people.” 22:00 - “It's this accomplice saboteur that works with the judge to create paralysis in us… the saboteurs are playing on all of our fears…and then on the sage side, there's really five superpowers of the sage.” - 24:23 - “It's a mental fitness model.” 24:25 - “You use the word superpowers… it has come up in several podcast episodes… I really love the idea of each of us becoming very intentional about what are my superpowers?” - 26:10 - “I found by asking, what is my superpower? For me, it's the combination of being prepared and staying curious. For you, it's something else.” 28:15 - “I know people that have superpowers… I can bring those Sherpas in with me. And then we can represent a team that's going to use superpowers like The Avengers… the goal is to find the right Avengers and accomplices to join you.” 29:05 - “You nailed it man, we are The Avengers… of corporate growth.”

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Alignment via prosocial brain algorithms, published by Cameron Berg on September 12, 2022 on LessWrong. In this post, I want to briefly propose a semi-novel direction for alignment research that I'm excited about. Though some of these ideas are not brand new—they purposefully bear resemblance to recent (highly promising) work in SHARD theory and Steve Byrnes's approach to brain-based AGI safety—I think my emphases are sufficiently different so as to justify a more thorough explanation. Why are humans 'worthy' of being in the loop? I think the following three claims help motivate the general research direction I have in mind. 1) Many of the most coherent AI safety strategies proposed to date (e.g., HCH, imitative and approval-based amplification, recursive reward modeling, and more) involve human decision-makers in some meaningful capacity. I claim, therefore, that these proposals implicitly presuppose that there are specific algorithmic properties of the human mind/brain that make us comfortable entrusting these ‘humans in the loop' with the task of minimizing the likelihood of AI-induced bad outcomes. This idea is demonstrated especially clearly by ‘safety via debate,' for instance: 2) I think the special brain algorithms in question—e.g., the ones that make us comfortable entrusting a neurotypical human to decide who won in the set-up above—are more familiarly thought of as prosocial or moral cognition. A claim like this would predict that we would be uncomfortable entrusting humans who lacked the relevant prosocial instincts (e.g., psychopaths) to oversee a safety-via-debate-type set-up, which seems correct. I think the reason that it is a very natural thought to want to incorporate neurotypical human decision-makers into alignment proposals is that we are confident (enough) that such decisions will be made carefully—or at least more carefully than if there were no humans involved. In other words, individual humans in the loop are entrusted-by-default to serve as competent advocates for the interests of society at large (and who are more than likely aware of the fact that they are serving this role), able to infer suspicious behavior, evaluate subtle short- and long-term predicted consequences, be humble about said evaluations, probably solicit second opinions, etc.—somehow! 3) Our understanding of human prosocial cognition is growing increasingly precise and predictive. In cognitive neuroscience writ large, computational modeling has become a dominant approach to understanding the algorithms that the human brain instantiates, with talented researchers like Joshua Tenenbaum, Robb Rutledge, and Anne Collins leading the charge. This work has taken off in recent years and has enabled cognitive scientists to define and test hypotheses that are unprecedented in their mathematical precision and predictive power. Here are two good introductory (1, 2) examples of this sort of work that pertain explicitly to human prosocial cognition. I expect my future writing—and that of others interested in this sort of approach—to feature far more examples of good alignment-relevant computational social neuroscience research. With these ideas in mind, my proposal is to conduct technical research to better understand these prosocial brain algorithms with the ultimate goal of instantiating some refined version of them directly into a future AGI (which is likely doing something approximating model-based RL). Here is a pretty straightforward two-step plan for doing so: Synthesize high-quality social neuroscience literature—with a particular focus on good computational modeling work—in order to more fully develop a rigorous account of the most important algorithms underlying human prosocial behavior. Develop specific corrigibility proposals for instantiating these algorithms in AI systems i...

Welcome back BSrs, to another ingredient song edition of Belonging Songs!  For those not familiar with our ingredient song episodes, it's where we pull different song elements  at random, then are required to use those elements to create the song. The categories we pull from are: tempo, theme, tone, special criteria, and special item.Other Ingredient Song Episodes:S1E29 - Trail Blazin'S1E39 - I've Got Great Love For YouS2E23 - Modern TechnologyS2E25 - Through, But NothingS3E09 - Artificial TearsRECIPEFill a bowl full of ice, then dump half out. Repeat indefinitely.Swirl at a moderately high tempo; water will pool, this is desirable. Synthesize happy-ish speech and infuse for flavor (a little goes a long way).Ponder your life and existence until flummoxed.Strain and serve in your finest crystal. Remember to forget this ever happened. Start at the beginning. Visit our website! www.belongingsongs.comCheck out our Instagram! https://www.instagram.com/belongingsongs/Follow us throughout the week for your latest BS news. This is where we do most of our social media-ing. Our stand-alone songs are available online! (Spotify, iTunes, Pandora. etc.)Search: Harnol Slin (Wade), Uzi Royal (Brad), Vonlio (Patrick), and/or The Whyte Spydrz.Give this free playlist a listen (updated weekly), it's got all the songs!Spotify: https://open.spotify.com/playlist/5CjxRurmyafbXVJwGkRReY

Jahan Marcu, PhD and Nigam B. Arora, PhD are joined by Sara Jane Ward, PhD and Jim Mitchell, PhD the Vice President, API Research and Development at Benuvia Manufacturing. The discussions begin with a deep dive into cannabis and psychedelics policy and research developments, highlighting that it feels as though psychedelics are skipping the line, passing cannabinoids, into the regulatory party. For rapid fire science we discuss cutting technology around synthesizing psychedelic compounds and cannabinoids. Learn why you should care about modern chemistry and its approaches to psychedelics and cannabinoid drug manufacturing needs for clinical research.Episode's Group:Jahan Marcu, PhD (moderator) Nigam B. Arora, PhDSara Jane Ward, PhDJim Mitchell, PhDNews and Popular Literature Links: Cannabis Legalization Gets Cold Shoulder (3:00)The Psychedelic Landscape: Pharma, tech, decrim, other (17:40)Additional Resource: https://psilocybinalpha.comTherapy for the UK - “It's coming sometime and maybe” (32:35)Rapid Fire Science Study Links:Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, baeocystin, norpsilocin, and aeruginascin (45:50)A Novel and Practical Continuous Flow Chemical Synthesis of Cannabidiol (CBD) and its CBDV and CBDB Analogues (1:06:55)Today's Game (1:26:00) : Welcome to today's GAME, today our group will be playing for the grand prize of helping to expand scientific thought. Today's game is Name That Drug! - The moderator summarizes a case report about psychedelics, cannabis, or another commonly used drug; the participants must guess which drug, either de novo or from four choices. It's not whether you guess the correct drug but how you ‘think' through this game.Credits:Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Ivan Artucovich, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode. More at: howtolaunchanindustry.com marcu-arora.com

Hi, docs! You need today's episode. It's all about the literature review. I'm sharing five (5) ways to nail it! Synthesize the literature like a pro and write with confidence. This can be done if you:Compare commonalities and contrast/ show differences.Identify relationships among the different studies. Comment on major themes and patterns you discovered on the topic and how it ties in with your study.Discuss the pros and cons and how they connect with your study.Point out gaps in the literature.https://www.dissertationdr.usGet Rich Teachers Sleep Well Now

Consciousness downloads, Vocal synthesizers, chatbots.... are we nearing the end of the need for humanity?

Synthesize Your Unique Journey into a Business with Spring Groove Episode #30 Spring Groove is a former Broadway Performer, an International Touring Artist w/ 12 original CDs, the creator of the Sing Yourself Alive MasterClass - & the proud founder of Y.U.M.M.Y. Time TM- (Your Ultimate Music Meditation Yoga Time). Spring delivers Musical Medicine & Peace of Mind fusing her training from The Boston Conservatory (BFA) and The Sivananda Vedanta Center (TTC), along with her Broadway, Busking & Bhakti EXPERIENCE. In this episode you'll learn:  To Give Yourself Permission To Slow Down What is Your Ultimate Meditation Music Time How to Take Parts of the Self and Synergize Your Business  

Discovering your own competitive advantage is at the heart of this week's conversation with author and podcaster Cody Royle. His book, Where Others Won't: Taking People Innovation from the Locker Room into the Boardroom, delves deep into lessons from teams around the world on leadership theory, group dynamics, and talent optimization. This week, he shares what he's learned about what both individuals and teams can do to find their niche. Royle says the big takeaway former athletes have going forward to a new career is their sense of self-awareness. Athletes spend much of their time getting feedback from others, be they coaches or fellow players. That helps them understand their strengths and weaknesses and explore what they enjoy doing and what they don't. That understanding is a critical asset outside the world of sports, as well, and can help a person find their best fit in business or whatever they ultimately pursue. What You'll Learn: Ask questions to build self-awareness Develop a leadership mentality Synthesize different parts of your personality Identify what you enjoy and what you don't and push for the right position Think outside the box to create a competitive advantage Learn more about Cody's work here.