Podcasts about cialis

C'est un sujet qui fait trembler plus d'un chef d'entreprise : le recrutement.Selon l'enquête BMO 2026 de France Travail, 43,8 % des projets de recrutement sont jugés difficiles par les entreprises.Ils atteignent mêmes des niveaux supérieur dans certains secteurs comme Le commerce et la réparation automobile (66,5 %), la métallurgie (65,9 %) et le BTP (65 %) ou bien encore La santé (54 %), le numérique (49,5 %) et l'industrie (48 %) sont également très concernés.Inadéquation des profils, manque de candidature, manque de moyens financiers ou bien encore déficit d'image les problèmes sont multiples.Le défi n'est pas seulement quantitatif (à savoir trouver des candidats) mais surtout qualitatif : attirer les bons profils dans un marché où les candidats sont plus exigeants sur le sens du travail, les conditions et la réputation de l'employeur.Aymeric Tournay est dirigeant fondateur du cabinet de recrutement Atout Search créé en 2017, spécialisé dans l'accompagnement des entreprises industrielles et des services pour le recrutement de cadres et d'experts.Diplômé de l'INSEEC Paris, il commence sa carrière dans des cabinets de recrutement (ex: Attitudes, Menway) avant de rejoindre le Groupe Adecco, où il participe au lancement de la marque Spring (aujourd'hui LHH) et développe la division Industrie à Paris.Depuis 2026, il est également certifié pour accompagner des personnes lors de bilans de compétences, finançables via le CPF.Retrouvez l'interview passionnante d'Aymeric au micro de Geoffroy Regouby dans ce nouvel épisode de Quartier d'affaires, le podcast du monde de l'entreprise.Vous appréciez ce podcast ? Soutenez-nous en vous abonnant et en mettant 5 étoiles ⭐Un podcast produit par Suniwan et enregistré « localement :-)» à Montrouge au studio Time-Line FactoryEnregistrement et Montage : BaptisteHébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

Aujourd'hui, nous avons échangé avec Emma, psychologue clinicienne, consultante RPS, créatrice de la méthode BO‑7 et autrice.Emma se définit par trois valeurs : Pragmatisme, Exploration, Ambition.Dans cet épisode, nous avons notamment parlé d'enquête harcèlement, de burn-out, de son dépistage et du programme de formation BO-7.C'était enrichissant ! Je vous laisse découvrir tout ça.Enjoy ! Où retrouver Emma : Linkedin : https://www.linkedin.com/in/emmapitzalis/Questionnaire clinique de dépistage du burnout (gratuit) : https://formations.emmapitzalis.com/diagnosticBlog prevention RPS / burnout : https://emmapitzalis.com/blog/

He was 22, drunk, and couldn't get an erection. That night followed him for the next decade.In this episode of Sex Advice for Seniors, Tom Jenkins, author of The Drunk Gambler with Erectile Dysfunction, joins me for one of the most honest conversations I've had about ED. We get into addiction, performance anxiety, why Cialis wasn't the answer, and the lifestyle overhaul that actually worked. Tom's story is younger than my usual guests, but the patterns he describes- shame, silence, treating the symptom instead of the cause show up at every age.If you've been too embarrassed to have this conversation, this is a good place to start. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sexadviceforseniors.com/subscribe

Entre ce que l'on veut montrer et ce que les autres perçoivent, il existe parfois un écart.Dans cet épisode, je reçois Myrtille Ronteix, céramiste et fondatrice de l'Atelier Monochrome, et Amandine Labrune, directrice de création et fondatrice du Studio 421.Ensemble, elles racontent un travail qui consiste à clarifier son univers, faire des choix, sélectionner ce que l'on montre et construire une identité visuelle cohérente avec ce que l'on est.À travers leur collaboration, elles partagent leurs réflexions sur les images, les mots, la cohérence graphique et la manière dont une identité visuelle peut devenir un véritable outil de développement pour un artisan d'art.Si vous avez aimé l'épisode, n'oubliez pas les 5 étoiles sur Apple podcast ou Spotify ;)Enfin, si vous voulez décrypter l'artisanat d'art avec nous, inscrivez-vous à notre⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ et rejoignez-nous sur les réseaux sociaux @⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠artisansdavenir⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠,⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠,⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Linkedin⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠).Si vous voulez acheter le livre "Profession artisan d'art" que nous avons écrit, il est disponible dans toutes les librairies et peut se commander ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠depuis notre site internet⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Pour nous rejoindre, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ c'est par ici⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠!⁠⁠⁠

We turn back the clock to review WWE No Way Out 2007. The biggest main event in WWE history sees John Cena and Shawn Michaels team up to face The Undertaker and Batista, JBL was wilding on commentary, Booker T needs an arena named after him, Bobby Lashley hasn't aged, Mr. Cialis + more.

Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- I spent a really long time putting this together, I really hope you enjoy it! In this inaugural episode of Mostly Wise, we explore: The non-sexual benefits of tadalafil (Cialis). Why Retardmaxxing might be the most underrated life hack. The strange reasons why people are making AI clones of their exes. Why America is addicted to lawsuits. If Love Island is harder than Navy SEAL selection training. and much more Guests Matt McCusker is a comedian, writer, author, and podcaster Dr Andrew Huberman is a neuroscientist, Associate Professor at the Stanford University School of Medicine and a podcaster. Tom Segura is a comedian, podcaster, and actor. Sponsors: See discounts for all the products I use and recommend: ⁠⁠https://chriswillx.com/deals⁠⁠ Get up to $350 off the Eight Sleep Pod 5 at https://eightsleep.com/modernwisdom Get 35% off your first subscription on the best supplements from Momentous at https://livemomentous.com/modernwisdom Get 160+ lab tests for just $365 and save an extra $25 at https://functionhealth.com/modernwisdom Get 15% off your first order of my favourite Non-Alcoholic Brew at https://athleticbrewing.com/modernwisdom Get ChatGPT to explore ideas, solve problems, and learn faster at ⁠https://chatgpt.com Timestamps: (0:00) Should All Men Be Taking Erectile Dysfunction Medication? (5:24) The GLP-1-Free Way to Get Lean (8:28) Why Comedians Make Great Actors (14:02) What Science Reveals About Comedians (25:33) How Love Island Manipulates Sleep (30:39) Is Retardmaxxing the New Way of Living? (46:28) The Risk of Recreating Your Ex With AI (49:32) Has Surveillance Killed Serial Killers? (52:53) Falling is a Billion-Dollar Industry (57:57) Are NASA Conspiracies Going Too Far? (01:01:05) Are These the Craziest Conspiracy Theories? (01:12:00) The Origins of the Secret Service (01:17:08) Can Cannabis Trigger Psychosis? (01:24:01) Is Nostalgia Ruining the Present? (01:31:10) The Unexpected Benefits of Fap Naps (01:38:38) The Best Method to Optimise Your Sleep (01:45:32) Are Kids Becoming Smarter? (01:57:12) Is Hollywood Exploiting OnlyFans Creators? (01:59:58) Has Chris' Voice Been Stolen? (02:06:18) Are Clang Associations a Sign of Psychosis? (02:09:57) The Crazy Spending Habits of Johnny Depp (02:15:56) What Happens When You Don't Sleep? (02:19:19) Are Backyard Ultra Runners the Toughest Athletes? (02:23:04) Can You Get Shredded Sugarmaxxing? (02:25:47) Does the Marshmallow Test Hold Up? (02:31:38) Is Sunscreen Actually Bad For You? (02:40:20) Where to Find the Guys Extra Stuff: Get my free reading list of 100 books to read before you die: ⁠⁠https://chriswillx.com/books⁠⁠ Try my productivity energy drink Neutonic: ⁠⁠https://neutonic.com/modernwisdom⁠⁠ Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: ⁠⁠lnkfi.re/SN-Goggins⁠⁠ #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: ⁠⁠lnkfi.re/SN-Peterson⁠⁠ #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: ⁠⁠lnkfi.re/SN-Huberman⁠⁠ - Get In Touch: Instagram: ⁠⁠https://www.instagram.com/chriswillx⁠⁠ Twitter: ⁠⁠https://www.twitter.com/chriswillx⁠⁠ YouTube: ⁠⁠https://www.youtube.com/modernwisdompodcast⁠⁠ Email: ⁠⁠https://chriswillx.com/contact⁠⁠ - Learn more about your ad choices. Visit megaphone.fm/adchoices

Dans cet épisode de "Comment j'ai réussi ?", Stéphane Pedrazzi reçoit Charles Egly, président et cofondateur de la fintech Younited. Ensemble, ils reviennent sur le parcours de son entreprise qui propose des solutions de paiement et de crédit instantanées grâce à l'utilisation des données bancaires de ses clients.Tout au long de l'entretien, Charles Egly lève le voile sur les défis et les innovations qui ont permis à Younited de devenir rentable en seulement quelques années. Il explique notamment comment l'accès aux données bancaires de ses clients via l'open banking permet à Younited de proposer des réponses de crédit quasi-immédiates, sans justificatifs, tout en limitant les risques. Un point particulièrement intéressant concerne l'évolution de la réglementation sur le paiement fractionné en France. L'invité apporte un éclairage nuancé sur les enjeux de cette réforme, soulignant à la fois les bénéfices pour le consommateur et les risques de surendettement. Ils abordent également l'impact potentiel de la hausse des taux d'intérêt sur le marché du crédit. Charles Egly partage son point de vue selon lequel une telle augmentation, si elle n'est pas forcément souhaitable, ne devrait pas avoir de conséquences dramatiques dans le contexte économique actuel.Enfin, le cofondateur revient sur la stratégie de diversification de United, qui s'est récemment renforcée avec l'acquisition d'Elios. Cette opération permet à la fintech de s'ouvrir à de nouveaux produits bancaires, au-delà de son cœur de métier initial.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

I spent a really long time putting this together, I really hope you enjoy it! In this inaugural episode of Mostly Wise, we explore: The non-sexual benefits of tadalafil (Cialis). Why Retardmaxxing might be the most underrated life hack. The strange reasons why people are making AI clones of their exes. Why America is addicted to lawsuits. If Love Island is harder than Navy SEAL selection training. and much more Guests Matt McCusker is a comedian, writer, author, and podcaster Dr Andrew Huberman is a neuroscientist, Associate Professor at the Stanford University School of Medicine and a podcaster. Tom Segura is a comedian, podcaster, and actor. Sponsors: See discounts for all the products I use and recommend: ⁠⁠https://chriswillx.com/deals⁠⁠ Get up to $350 off the Eight Sleep Pod 5 at https://eightsleep.com/modernwisdom Get 35% off your first subscription on the best supplements from Momentous at https://livemomentous.com/modernwisdom Get 160+ lab tests for just $365 and save an extra $25 at https://functionhealth.com/modernwisdom Get 15% off your first order of my favourite Non-Alcoholic Brew at https://athleticbrewing.com/modernwisdom Get ChatGPT to explore ideas, solve problems, and learn faster at ⁠https://chatgpt.com Timestamps: (0:00) Should All Men Be Taking Erectile Dysfunction Medication? (5:24) The GLP-1-Free Way to Get Lean (8:28) Why Comedians Make Great Actors (14:02) What Science Reveals About Comedians (25:33) How Love Island Manipulates Sleep (30:39) Is Retardmaxxing the New Way of Living? (46:28) The Risk of Recreating Your Ex With AI (49:32) Has Surveillance Killed Serial Killers? (52:53) Falling is a Billion-Dollar Industry (57:57) Are NASA Conspiracies Going Too Far? (01:01:05) Are These the Craziest Conspiracy Theories? (01:12:00) The Origins of the Secret Service (01:17:08) Can Cannabis Trigger Psychosis? (01:24:01) Is Nostalgia Ruining the Present? (01:31:10) The Unexpected Benefits of Fap Naps (01:38:38) The Best Method to Optimise Your Sleep (01:45:32) Are Kids Becoming Smarter? (01:57:12) Is Hollywood Exploiting OnlyFans Creators? (01:59:58) Has Chris' Voice Been Stolen? (02:06:18) Are Clang Associations a Sign of Psychosis? (02:09:57) The Crazy Spending Habits of Johnny Depp (02:15:56) What Happens When You Don't Sleep? (02:19:19) Are Backyard Ultra Runners the Toughest Athletes? (02:23:04) Can You Get Shredded Sugarmaxxing? (02:25:47) Does the Marshmallow Test Hold Up? (02:31:38) Is Sunscreen Actually Bad For You? (02:40:20) Where to Find the Guys Extra Stuff: Get my free reading list of 100 books to read before you die: ⁠⁠https://chriswillx.com/books⁠⁠ Try my productivity energy drink Neutonic: ⁠⁠https://neutonic.com/modernwisdom⁠⁠ Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: ⁠⁠lnkfi.re/SN-Goggins⁠⁠ #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: ⁠⁠lnkfi.re/SN-Peterson⁠⁠ #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: ⁠⁠lnkfi.re/SN-Huberman⁠⁠ - Get In Touch: Instagram: ⁠⁠https://www.instagram.com/chriswillx⁠⁠ Twitter: ⁠⁠https://www.twitter.com/chriswillx⁠⁠ YouTube: ⁠⁠https://www.youtube.com/modernwisdompodcast⁠⁠ Email: ⁠⁠https://chriswillx.com/contact⁠⁠ - Learn more about your ad choices. Visit megaphone.fm/adchoices

Entre droits de douane américains, attaques en mer Rouge et explosion du coût du fret, la filiale kényane d'Olvea doit composer avec une succession de chocs géopolitiques. Mais ces turbulences créent aussi de nouvelles opportunités pour la transformation locale. À quelques kilomètres de Nairobi, des montagnes d'avocats patientent dans un vaste entrepôt avant d'être transformées en huile. Ici, dans l'usine kenyane du groupe français Olvea, la cadence dépend autant des récoltes que des secousses géopolitiques mondiales. Guerre au Moyen-Orient, attaques des Houthis en mer Rouge, tensions commerciales avec les États-Unis : chaque crise redessine les équilibres économiques de cette filière en pleine expansion. « Ces fruits sont en maturation et seront mis en production dans les jours qui viennent », explique Jean Arnaud Janvier, directeur d'Olvea Kenya. Ces avocats seront transformés en huile, un produit particulièrement recherché sur le marché américain où les prix restent très élevés. Olvea, déjà implanté dans plusieurs pays africains pour la production d'huiles végétales, a choisi de miser sur cette filière en forte croissance. « C'est une huile qui est consommée quotidiennement par les Américains, une huile de table incluse dans la mayonnaise et qui sert à fabriquer les snacks aux États-Unis, détaille Emmanuel Petiot, directeur des huiles végétales chez Olvea. Donc, en tant que société PME-ETI normande déjà impliquée dans la fabrication d'huile en Afrique, puisque notre modèle, c'est de fabriquer en Afrique, de construire des usines, on s'est dit qu'on devait participer à la fête de l'huile d'avocat. » Les droits de douane de Trump rebattent les cartes Mais la guerre commerciale engagée par Washington complique les perspectives du groupe français. L'augmentation des droits de douane américains pénalise directement les exportateurs européens, face à la concurrence mexicaine. « On est désavantagés par rapport à un pays qui est le Mexique. Le Mexique est le plus gros producteur d'huile d'avocat. Eux n'ont pas de droits de douane pour aller aux États-Unis, alors que nous, on subit 10%. Donc on a de facto un désavantage de 10%, étant Européens par rapport aux Mexicains. Donc c'est clairement un problème, mais on ne peut pas y faire grand chose. Donc l'idée, c'est qu'il faut qu'on soit meilleurs ici en Afrique. Il faut qu'on arrive à tirer ce qu'on appelle "les rendements" de notre production, les meilleurs possibles et si possible meilleurs qu'au Mexique », développe Emmanuel Petiot. Autre conséquence des tensions géopolitiques : les perturbations du commerce maritime mondial. Avec la guerre au Moyen-Orient et les difficultés de circulation dans le détroit d'Ormuz, les coûts du transport maritime se sont envolés. Résultat : les avocats frais kenyans s'exportent moins facilement, ce qui augmente les volumes disponibles pour la transformation locale. « Le goulot d'étranglement à l'export pour les fruits frais a un peu augmenté la disponibilité des fruits pour l'huile, explique Jean Arnaud Janvier, et ensuite pour l'aspect négatif comme pour tous ceux qui sont dans la logistique internationale, le coût et les temps de transport entre l'Afrique et l'Europe qui ont été augmentés, le coût du fret, lui, a doublé et parfois triplé. » À lire aussiGuerre commerciale: en Afrique, les effets collatéraux du bras de fer Pékin-Washington Une huile au rendement limité Avant même les tensions autour du détroit d'Ormuz, les attaques houthis en mer Rouge avaient déjà obligé le groupe à modifier ses routes maritimes, en passant par le cap de Bonne-Espérance. Cela ne décourage pas Emmanuel Petiot : « C'est du gâchis, c'est tout. Ça met quelques obstacles sur notre chemin. Il est bien évident qu'investir est plus compliqué, donc on réfléchit plutôt deux fois qu'une avant d'investir dans un projet X ou Y. Mais ça nous aide aussi à prendre des décisions qui sont encore meilleures. Il faut absolument qu'on arrive à passer ces obstacles et à se dire que c'est une situation temporaire et qu'il faut aller de l'avant. » D'autant que la rentabilité de cette activité reste fragile : l'huile d'avocat offre un rendement relativement faible. L'installation kényane peut traiter jusqu'à 160 tonnes de fruits par jour, pour une production de seulement 16 000 litres d'huile. À lire aussiL'avocat kényan en mauvaise posture face à la vague péruvienne

On this episode of The Armor Men's Health Show, Dr. Mistry and Donna Lee kick things off with a couple of delightfully cringe-worthy urology jokes before diving into listener questions that are packed with useful information and real-life concerns.

An angry & fired up Tim Schneider shares his take of the day!

Full Show Broadcast. Buffalo Bills Greg Rousseau & Matthew Fairburn on the show. Gene reacts to the Sabres game 5 loss & the Bills 2026-27 schedule. Timmy has his take. Gene shares shots & last call.

Gene has schedule leaks: The Buffalo Bill play week 1 in Houston. Plus other not officially announced games.

Steve et Rose Haldeman s'expriment aussi sur quatre sujets, en rapport avec leurs écrits :- les sexualités- la protection de l'enfance- le monde de l'entreprise- la science-fictionPour en savoir plus, vous pouvez les retrouver :- sur leur site internet : stevehaldeman.com- sur leur chaîne Youtube principale : https://www.youtube.com/@steveetrosehaldeman- et sur leurs autres réseaux sociaux, dont les liens sont disponibles sur la page d'accueil de leur site.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Steve et Rose Haldeman s'expriment sur quatre sujets, en rapport avec leurs écrits :- les sexualités- la protection de l'enfance- le monde de l'entreprise- la science-fictionPour en savoir plus, vous pouvez les retrouver :- sur leur site internet : stevehaldeman.com- sur leur chaîne Youtube principale : https://www.youtube.com/@steveetrosehaldeman- sur leur chaîne secondaire : https://www.youtube.com/@protectiondelenfance- et sur leurs autres réseaux sociaux, dont les liens sont disponibles sur la page d'accueil de leur site.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Bienvenue sur Avant j'étais prof, le podcast des enseignants en reconversion.Aujourd'hui, j'ai le plaisir d'échanger avec Nolwenn, une enseignante qui s'intéresse à l'enfant à l'intérieur de l'élève.Nolwenn a de nombreuses casquettes, qui vont toutes plutôt bien les unes avec les autres. La moitié de la semaine, elle est enseignante spécialisée au CAMPS (Centre d'Actions Médico-Sociales Précoces) via un détachement de l'Éducation nationale. Le reste du temps, elle est accompagnante parentale à son compte et forme les personnes qui souhaitent le devenir à leur tour.Il faut dire qu'avec 25 ans de carrière dans l'enseignement, un doctorat en psychologie du développement de l'enfant et une formation en techniques de parentalité relationnelle & positive, Nolwenn a plus que le nécessaire pour évoluer dans cette voie.Ce parcours, c'est la preuve qu'une reconversion n'est pas toujours une rupture. Ça peut aussi être une continuité.

Christophe Giltay revient sur tout ce qui fait l'actu. Le plus célèbre chroniqueur de bel RTL partage son avis et son humeur à l'heure du petit déjeuner ! Un édito sans concession avec la plume et le ton unique de Christophe Giltay.

Cette semaine, replay du printemps avec Veesion et son CEO Thibault, invité en septembre dernier.

durée : 00:04:04 - Le Grand reportage de France Inter - C'est une réalité qui touche de nombreux travailleurs, et dont l'étendue ne cesse de croitre depuis le Covid au sein de la société selon les soignants : le burn-out. Depuis trois ans, un centre spécialisé dans sa prévention et son traitement a ouvert ses portes au CHU de Toulouse. Reportage - réalisation : Victor Dhollande Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France

Send us a text & leave your email address if you want a reply!Is there an actual cure for erectile dysfunction? In this episode, Dr. Jeff Nuziard of Regen Max says yes, and he has a 97% success rate and a patent to back it up. Jeff breaks down why pills like Viagra and Cialis eventually stop working (hint: it is a tissue problem, not a blood flow problem), and walks us through the four-step regenerative protocol that rebuilds erectile tissue from the inside out using shockwave therapy, laser collagen remodeling, testosterone optimization, and a patented stem cell biologic injected directly into the spongiosum. We also get into why this same science applies to women dealing with clitoral atrophy, lost orgasmic sensitivity, and vaginal dryness, plus an honest take on what peptides like PT-141 and GHK-Cu can and cannot do. If you or someone you love has been told to just manage ED rather than fix it, this episode is going to change the conversation entirely.KEY TAKEAWAYS:The real cause of ED is spongiosum tissue degeneration, not poor blood flowTestosterone decline triggers collagen loss, which dries out erectile tissue over timePDE-5 inhibitors (Viagra, Cialis) stop working when there is no tissue left to absorb bloodA four-step regenerative protocol can restore full erectile function, including for post-prostatectomy patientsWomen experience the same tissue breakdown as clitoral atrophy and vaginal relaxation syndrome, and respond even faster to treatmentOral collagen supplements do not reach erectile tissue; direct injection is the only delivery that worksThe full Regen Max program is $10,000 for one year, all-inclusive, with financing availableLINKS, RESOURCES, BLOGS, & VIDEO VERSIONS OF THE EPISODE CAN BE FOUND HERE ROOTED IN DESIRE. A Journey Back to Your Feminine Essence If you're a heart-centered woman ready to embody your femininity, awaken your sacred sexuality, and fall deeply in love with yourself, this immersion is for you. Register: https://www.sexreimagined.com/rooted-in-desire THE MALE GSPOT & PROSTATE MASTERCLASS. This is for you if… You've heard of epic anal orgasms, & you wonder if it's possible for you too. Save 20% Coupon PODCAST20.  AWAKEN AROUSAL OIL LUBRICANT | Reach new levels of intimacy with our arousal oil, formulated for the female body. Once applied, this topical oil works with your body to enhance sensation and "o's," helping you reach states of euphoric pleasure.Support the showFREEBIE- Introduction to Tantric Kissing Video and WorkbookSxR WebsiteDr. Willow's WebsiteLeah's Website 

In this AMA episode, Dr. Rena Malik explains how to properly use Cialis (tadalafil) and Viagra, including timing, food, and why results improve with repeated use. She also covers edging—when it's safe and when it can cause pelvic tension—and why many women don't orgasm during sex, highlighting clitoral stimulation, positioning, and communication. Become a Member to Receive Exclusive Content: renamalik.supercast.com Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: Let's Connect!: WEBSITE: http://www.renamalikmd.com YOUTUBE: https://www.youtube.com/@RenaMalikMD INSTAGRAM: http://www.instagram.com/RenaMalikMD TWITTER: http://twitter.com/RenaMalikMD FACEBOOK: https://www.facebook.com/RenaMalikMD/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ TIKTOK: https://www.tiktok.com/RenaMalikMD ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices

The announcement the internet has been waiting on — Usher and Chris Brown just confirmed their joint stadium tour, dubbed the Raymond & Brown Tour — R&B. No dates yet. Iran War update — a ceasefire is technically in place. But Israel launched its biggest attack on Lebanon on day one of the deal. The Strait of Hormuz is still barely open. Iran is charging ships $2 million to pass through. JD Vance is heading to Pakistan for peace talks this weekend. We give you the full breakdown on where this is actually headed. A California company just recalled two chocolate products — after the FDA found they were secretly spiked with the active ingredients in Viagra and Cialis. They marketed it as 'aphrodisiac chocolate.' Turns out it was more pharmaceutical than anyone bargained for — and potentially life threatening for anyone on heart medication. Yes, this actually happened. The Ketamine Queen was sentenced to 15 years in the death of Matthew Perry — and we ask the real question — should drug dealers be held criminally responsible when users overdose? Matthew Perry was an adult who sought out these drugs. Where does personal accountability end and criminal liability begin? This is a real debate and we are having it. Diddy could be getting out sooner than you think — his lawyers were in federal appeals court TODAY arguing his 50-month sentence should be dramatically reduced. He was convicted on prostitution charges but the judge sentenced him based on conduct the jury said he was not guilty of. The appeals judges were skeptical — but the math on his release date is already moving. We break it all down. Judge Mathis is back with his wife — after what most people thought was a permanent split, Linda dismissed the divorce case and they are officially back together. We ask the question — would you go back after 20 years? What does that reconciliation actually look like? We get into it. All of that — plus more

Avec Charles Dard

Send us a text & leave your email address if you want a reply!We had an incredible chat with Dr. Elliot Justin that might literally save lives while spicing up bedrooms everywhere. Did you know? A significant drop in nighttime erections means a man has a 50% chance of having a heart attack within two years. Yep, your penis is trying to tell you something important! Dr. Justin, emergency physician turned sex tech innovator, has created the world's first comfortable, clip-on cock ring that not only monitors these crucial health signs but can dramatically improve your sex life. Whether you're concerned about heart health, dealing with "fading erections," recovering from prostate surgery, or simply want better sex, this episode delivers practical solutions based on groundbreaking research. Hit play to discover why monitoring your nighttime erections could be as important as checking your blood pressure (and way more fun to improve!).THE JUICY DETAILS:The Bedroom-Heart Connection: Healthy men typically have 3+ nocturnal erections nightly – fewer could signal cardiovascular issuesVenous Leak Explained: As we age, blood escapes the penis too quickly (yes, that's why your erection fades!)Beyond "Dysfunction": Why Dr. Justin prefers "erectile disappointment" and how this perspective changes everythingGame-Changing Design: A bra-inspired cock ring that clips on easily (no more awkward struggles!)Hard Science: The monitoring ring has collected data from 56,000+ erections – the largest such database everPerformance Boost: Clinical tests show the ring is equivalent to 10mg of Cialis and extends pleasure by up to 50%Relationship Saver: Men stay hard longer (up to 4 minutes after climax), creating more intimate momentsGet all of the Resources, Links, Show Notes, and the Full Video and Audio versions of this episode > HERE POWER OF PLEASURE | Join our FREE Live Online Summit - April 28-29, 2026 featuring 12 leading intimacy experts in conscious sexuality, desire and erotic healing. Register: https://www.sexreimagined.com/power-of-pleasure  ROOTED IN DESIRE. A Journey Back to Your Feminine Essence If you're a heart-centered woman ready to embody your femininity, awaken your sacred sexuality, and fall deeply in love with yourself, this immersion is for you. Register: https://www.sexreimagined.com/rooted-in-desire LAST 10x LONGER. If you suffer from premature ejaculation, you are not alone, master 5 techniques to cure this stressful & embarrassing issue once and for all. Save 20% Coupon: PODCAST20. Support the showFREEBIE- Introduction to Tantric Kissing Video and WorkbookSxR WebsiteDr. Willow's WebsiteLeah's Website 

Dr. Arthur Burnett called in to discuss erectile dysfunction causes, treatments and more. Tune in to hear all the details including how Dr. Arthur Burnett helped bring Viagra to market, what can causes erectile dysfunction and how it can be physical and/or psychological, how and why ED can be an early warning sign of cardiovascular disease and diabetes, why men shouldn't be embarrassed to talk about it, how testosterone affects libido vs. erections, what Trimix is and when it's used, how lifestyle changes like diet, sleep and weight loss can improve erections, how GLP-1 receptor agonists may impact sexual function, whether you can become dependent on Viagra or Cialis, the side effects of ED meds, all the treatment options from pills to pumps to penile implants and how they work, what a venous leak is and why it's hard to fix, how to know if your ED is normal aging or something more serious plus a whole lot more. Check out his book Manhood Rx GET A COPY OF THE STRICTLY ANONYMOUS BOOK! Strictly Anonymous Confessions: Secret Sex Lives of Total Strangers. A bunch of short, super sexy, TRUE stories. GET YOUR COPY HERE: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.to/4i7hBCd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ To see HOT pics of my female guests + hear anonymous confessions + get all the episodes early and AD FREE, join my Patreon! It's only $7 a month and you can cancel at any time. You can sign up here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.patreon.com/StrictlyAnonymousPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and when you join, I'll throw in a complimentary link to my private Discord! To join SDC and get a FREE Trial! click here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.sdc.com/?ref=37712⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or go to SDC.com and use my code 37712   Want to be on the show? Email me at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠strictlyanonymouspodcast@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.strictlyanonymouspodcast.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and click on "Be on the Show." Want to confess while remaining anonymous? Call the CONFESSIONS hotline at 347-420-3579. All voices are changed.   Sponsors: ⁠https://inda.shop/STRICTLY!⁠⁠ If you're 21 or older, get 40% OFF your first order @IndaCloud with code STRICTLY ⁠⁠⁠⁠https://beducate.me/pd2610-anonymous⁠⁠⁠⁠⁠⁠ — Click here to take the quiz and  get your personalized roadmap to sexual happiness ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.quince.com/strictlyanon⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ — For premium quality Quince clothing plus FREE shipping and 365 day returns! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bluechew.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ — Get 10% OFF your first month of Bluechew GOLD! Use code: STRICTLYANON⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://LoadBoost.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ — To get 10% off LOAD BOOST by VB Health use code: STRICTLY Follow me! Instagram  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/strictanonymous/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ X  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/strictanonymous?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Website  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.strictlyanonymouspodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Everything else: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/Strictlyanonymouspodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Justin Houman, a nationally recognized urologist and Assistant Professor of Urology at Cedars-Sinai Medical Center. Fellowship-trained and specializing in men's health, male fertility, and sexual medicine, Dr. Houman combines cutting-edge medical advancements with holistic lifestyle strategies to help men optimize testosterone, sexual health, and reproductive performance at every age. Together, Dave and Dr. Houman tear through the myths, the bad science, and the outdated medical dogma around testosterone, erectile function, fertility, and male sexual health. They cover everything from why testosterone levels have collapsed in a single generation, to the real story behind the FDA black box warning, to practical protocols for men who want to optimize without sacrificing fertility. This is the masterclass on men's health that no one else is having on record. This is essential listening for anyone serious about biohacking, longevity, human performance, hormone optimization, brain optimization, anti-aging, functional medicine, mitochondria, and Smarter Not Harder approaches to male health. You'll Learn: Why testosterone levels in 40-year-old men are 30 percent lower than their fathers and what is driving the collapse How low testosterone connects to anxiety, depression, high cholesterol, blood sugar dysregulation, and all-cause mortality risk The truth about the original testosterone and heart attack study and why it still has not been retracted How to preserve fertility while on TRT using Clomid, enclomiphene, and HCG Why daily low-dose Cialis is one of the cheapest and most effective longevity drugs available What shockwave therapy, PRP, exosomes, and Botox injections actually do for erectile function How red light therapy at 660 and 850 nanometers supports testosterone production and nocturnal erections The supplement stack including ashwagandha, tongkat ali, fadogia agrestis, and creatine that supports healthy hormone levels Why porn-induced ED is epidemic in young men and how to reverse it How PT-141 and peptides fit into a complete male optimization protocol Thank you to our sponsors! Pre-order Arthur Brook's new book today at themeaningofyourlife.com. You can also see Arthur speak live at the 2026 Beyond Biohacking Conference fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.Establish a powerful foundation for sustained wellness with Pique. Unlock 20% off: piquelife.com/DAVE BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: testosterone, low testosterone, TRT, testosterone replacement therapy, male fertility, erectile dysfunction, ED, men's health, sexual health, hormone optimization, Dave Asprey, biohacking, longevity, anti-aging, human performance, Dr. Justin Houman, Cedars-Sinai, urologist, shockwave therapy, PRP, exosomes, Botox penis, red light therapy, nitric oxide, Cialis, tadalafil, Viagra, sildenafil, PT-141, Melanotan, peptides, ashwagandha, tongkat ali, fadogia agrestis, creatine, Danger Coffee, Smarter Not Harder, Kyzatrex, clomid, enclomiphene, HCG, prolactin, cabergoline, porn-induced ED, refractory period, fertility, sperm health, spermatogenesis, FSH, LH, estrogen, aromatization, functional medicine, supplements, mitochondria, circadian rhythm, sleep optimization, cortisol, microplastics, inflammation, cardiovascular health, dementia, all-cause mortality, nocturnal erections, penile health, male optimization Resources: • Learn More About Dr. Houman's Work At: https://houmanmd.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Introduction 01:15 – Low Testosterone Epidemic 04:23 – Ejaculation & Testosterone 07:30 – Refractory Period & Aging 09:58 – Porn-Induced ED 11:09 – Cabergoline & Prolactin Management 12:42 – Oral Testosterone 13:24 – Testosterone Target Levels 16:46 – Supplements for Testosterone 18:46 – Anxiety-Based ED 26:23 – Penis Enhancement Options 27:37 – Shockwave Therapy 28:57 – Cialis for Longevity 29:56 – Fat & Filler Injections 34:50 – Pre-Sex Optimization 40:13 – Red Light Therapy 42:18 – Heat & Cold for Testosterone 43:35 – Underwear & Microplastics 44:58 – Testosterone & Fertility 49:15 – HCG & Preserving Fertility 52:00 – Testosterone Dosing Timing 53:22 – Creatine & Mitochondrial Health 55:20 – Overtraining Effects 56:24 – Peptides (PT-141) 59:08 – Optimal Diet for Fertility See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Docteur en intelligence artificielle, Julien Launay a démarré sa carrière au sein de la startup française LightOn, pionnière du calcul photonique. À la fin des années 2010, alors que les premiers modèles Transformer émergent, il travaille sur l'entraînement de modèles de langage à l'aide de coprocesseurs optiques. Il contribue alors à des projets open source comme Bloom. En 2023, il cofonde Adaptive ML avec l'objectif de résoudre l'un des nouveaux défis de l'IA générative : l'adaptation des modèles aux besoins des entreprises. La jeune pousse développe une plateforme exploitant l'apprentissage par renforcement (« reinforcement learning ») pour spécialiser les modèles de langage. L'idée est simple : après une phase de pré-entraînement où le modèle apprend le langage à partir d'immenses corpus de textes, une phase dite de « post-training » permet de l'optimiser pour des tâches précises — par exemple le support client, la détection de fraude ou l'interaction avec des outils internes. Cette spécialisation présente un double avantage : améliorer la pertinence des réponses et surtout réduire drastiquement les coûts de calcul. Selon Julien Launay, les entreprises peuvent ainsi diminuer de 50 % à 90 % leurs dépenses liées à l'IA en remplaçant des modèles généralistes par des modèles plus petits et spécialisés. Basée entre Paris, New York et Toronto, Adaptive ML cible principalement de grandes entreprises nord-américaines — notamment dans les télécoms, l'assurance ou le transport aérien — où l'utilisation massive d'agents d'IA génère des volumes colossaux de données et donc des coûts élevés. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Pascal Praud revient pendant deux heures, sans concession, sur tous les sujets qui font l'actualité. Vous voulez réagir ? Appelez le 01.80.20.39.21 (numéro non surtaxé) ou rendez-vous sur les réseaux sociaux d'Europe 1 pour livrer votre opinion et débattre sur les grandes thématiques développées dans l'émission du jour.Vous voulez réagir ? Appelez-le 01.80.20.39.21 (numéro non surtaxé) ou rendez-vous sur les réseaux sociaux d'Europe 1 pour livrer votre opinion et débattre sur grandes thématiques développées dans l'émission du jour.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

durée : 00:05:29 - L'invité de 6h20 - par : Mathilde MUNOS - Un premier vol organisé pour rapatrier des Français bloqués au Moyen-Orient depuis le début de la guerre est arrivé tôt mercredi matin à l'aéroport Roissy-Charles de Gaulle en provenance d'Oman. Environ 400 000 Français sont actuellement dans la région, plus de la moitié en Israël. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.

Erectile dysfunction is showing up earlier in men's lives than ever before, and the reasons go far beyond what most people assume.In this episode, you'll learn how everyday habits (some that seem harmless) may be quietly affecting your performance, confidence, and long-term health. You'll also get insight into why ED looks different in your 20s compared to your 40s and 50s, and why simply relying on medication may not be enough.If you're ready to understand what might really be happening and what steps could start turning things around, tune in to the full episode and listen now.--------------Key TakeawaysErectile dysfunction is increasing in men under 35 due to lifestyle habits.Porn overconsumption can desensitize your brain and impact erections.Smoking, vaping, and marijuana can restrict blood flow and worsen ED.A sedentary lifestyle significantly contributes to erectile dysfunction.After age 35, ED is often linked to high blood pressure, cholesterol, or diabetes.Erectile dysfunction can be an early warning sign of heart disease.Cialis may become less effective if the root cause of ED isn't addressed.Diet and regular exercise are the true foundation for reversing ED.Quality sleep supports hormone balance and sexual performance.Addressing stress and performance anxiety can improve psychological ED.--------------Resources mentioned:Modern Man CribMediterranean DietGood Morning Wood SmoothieRenew with Dr. Anne--------------Curious about how you can boost your bedroom game and build lasting confidence? Check out the course at getwoodnow.com and start your journey to feeling like yourself again!--------------If you enjoyed this episode and want to learn more and get more tips, subscribe to The Modern Man newsletter for exclusive content delivered straight to your inbox! https://dranne.co/themodernman--------------Follow Me On:InstagramTwitterFacebookTikTokYouTube--------------For all links and resources mentioned on the show and where to subscribe to the podcast, please visit https://truongrehab.com/reverse-erectile-dysfunction-naturally-fast--------------Want to regain control of your sex life? It's time to reverse the effects of ED on your life. Join the Modern Man Club and embark on your journey to complete recovery and community.--------------Reveal the FREE treatment most men ignore that solves thousands of erectile dysfunction cases every year, plus the 5 biggest mistakes you must avoid if you want to say goodbye to your ED. Uncover it all in my free eBook, available to download now.https://dranne.co/ebook

This week on The Armor Men's Health Show podcast, Donna Lee sits down with a very special guest — board-certified urologist Dr. Lucas Jacomides — for an honest, informative, and incredibly helpful conversation.They dive into a listener question many men quietly struggle with: “I had a prostatectomy in 2016 and have developed ED since then. I've tried Viagra and Cialis with no success. Is there help?”Dr. Jacomides breaks down why medications don't usually work after a prostatectomy and, more importantly, shares the real options available that can restore confidence, intimacy and quality of life.Got a question of your own? Visit www.armormenshealth.com and submit it — your question will be answered anonymously by a board-certified urologist on a future episode.Thanks for listening, laughing, and learning with us. If this episode helps you (or someone you love), be sure to share the podcast — and we'll see you right back here next week!

This episode explores tadalafil (Cialis) as a potential longevity drug, though no randomized human trials prove it extends lifespan. Cialis works by blocking PDE5, enhancing nitric oxide signaling, and improving blood flow through vasodilation. Originally approved for pulmonary hypertension, it's also used for erectile dysfunction and BPH. Its 36-hour half-life makes it superior to Viagra for continuous longevity effects.   The host frames vascular aging and endothelial dysfunction as key drivers of age-related diseases (heart disease, stroke, dementia, kidney disease). Observational data shows Cialis users have 44% lower mortality, fewer cardiovascular events, reduced dementia risk, and lower mortality in diabetics. Additional benefits include improved cardiac function, reduced infarct size, arrhythmia suppression, and regression of left ventricular hypertrophy. A 2024 meta-analysis found it lowers hemoglobin A1C, possibly via improved microvascular perfusion, insulin sensitivity, and mitochondrial function.   Cialis crosses the blood-brain barrier and may improve neurovascular coupling and hippocampal plasticity, potentially benefiting those with or at risk of dementia. Safety is generally good with long-term daily use (2.5–5 mg), though cautions include avoiding use with nitrates, low blood pressure, or certain retinal disorders. Common side effects are headache, nasal congestion, and acid reflux. The host recommends consulting a doctor and references potential synergy with telmisartan.   Tadalafil (Cialis) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a604008.html](https://medlineplus.gov/druginfo/meds/a604008.html) Sildenafil (Viagra) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a699015.html](https://medlineplus.gov/druginfo/meds/a699015.html)   Key mechanisms mentioned Nitric Oxide (NO) — NCBI Bookshelf: [https://www.ncbi.nlm.nih.gov/books/NBK554485/](https://www.ncbi.nlm.nih.gov/books/NBK554485/) Cyclic GMP (cGMP) — NCBI Bookshelf: [https://www.ncbi.nlm.nih.gov/books/NBK542234/](https://www.ncbi.nlm.nih.gov/books/NBK542234/)   Conditions mentioned in the episode Benign Prostatic Hyperplasia (BPH) — MedlinePlus: [https://medlineplus.gov/benignprostatichyperplasia.html](https://medlineplus.gov/benignprostatichyperplasia.html) Pulmonary Arterial Hypertension (PAH) — MedlinePlus: [https://medlineplus.gov/pulmonaryhypertension.html](https://medlineplus.gov/pulmonaryhypertension.html)   Blood pressure drug mentioned Telmisartan — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a601249.html](https://medlineplus.gov/druginfo/meds/a601249.html)   Other longevity / comparison drugs mentioned Metformin — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a696005.html](https://medlineplus.gov/druginfo/meds/a696005.html) Sirolimus (Rapamycin) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a602026.html](https://medlineplus.gov/druginfo/meds/a602026.html)   Side-effect helper mentioned Ibuprofen (Advil) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a682159.html](https://medlineplus.gov/druginfo/meds/a682159.html)   Dementia meds mentioned Donepezil (Aricept) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a697032.html](https://medlineplus.gov/druginfo/meds/a697032.html) Amantadine — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a682064.html](https://medlineplus.gov/druginfo/meds/a682064.html)   Lab markers mentioned Hemoglobin A1C (HbA1c) test — MedlinePlus lab test: [https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/](https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/) Insulin in blood test — MedlinePlus lab test: [https://medlineplus.gov/lab-tests/insulin-in-blood/](https://medlineplus.gov/lab-tests/insulin-in-blood/)   People referenced (where the claims were mentioned) Huberman Lab (Dr. Andrew Huberman) — site: [https://www.hubermanlab.com/](https://www.hubermanlab.com/) Clip about low-dose tadalafil (2.5–5mg) — X post: [https://x.com/tbpn/status/2022350426394534334](https://x.com/tbpn/status/2022350426394534334) Bryan Johnson (Blueprint) — site: [https://blueprint.bryanjohnson.com/](https://blueprint.bryanjohnson.com/) Dr. David Sinclair (Harvard profile) — site: [https://sinclair.hms.harvard.edu/people/david-sinclair](https://sinclair.hms.harvard.edu/people/david-sinclair)   Show Notes   00:00 Welcome to the Hart2Heart Podcast. 01:56 What Cialis Is: PDE5 Inhibition, cGMP & Nitric Oxide Explained 03:43 Approved Uses & Origin Story: Pulmonary Hypertension, ED, and BPH 05:33 Why Cialis Over Viagra: 36-Hour Half-Life & 24/7 Vascular Benefits 06:52 Vascular Aging 101: Endothelium, Perfusion, and Why It Drives Disease 11:14 What the Human Data Shows: Observational Evidence for Mortality, CVD & Dementia 13:04 Mechanisms Deep Dive: Heart Protection, Heart Failure, and Anti-Atherosclerosis 15:02 Cialis for Diabetics: Lowering A1C and Improving Insulin Sensitivity 16:21 Brain Effects: Blood–Brain Barrier, Neurovascular Coupling & Dementia Potential 18:21 Safety, Who Should Avoid It, and Daily Longevity Dosing (2.5–5 mg) + Wrap-Up   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

(00:00:00) Opening (00:01:38) A PIece of My Mind (00:07:12) Pancho Guero, My Insane FL Nephew (00:26:36) Man Jailed for Murder Goes Viral After Worrying He'd Miss Video Game Release (00:32:33) Chatbots Were Sent to Therapy and THIS What Came Out (00:40:04) ⅓ of College Students Scroll Phones While 'Getting Busy' (00:47:02) FDA Recalls “Horny” Honey—Because It's Loaded with Cialis (00:52:17) Olympic Officials Investigate Penis Injection Doping Claims In Ski Jumping (00:59:31) Booty From A Dead Person? Women Chasing the Perfect Body Are Pumping ‘Ethically Sourced' Cadaver Fat Into Boobs and Butt (01:08:34) A Man Will Be Charged After Sticking a World War One Bomb Up His Butt (01:12:46) Ask Pancho (01:26:34) Insane Game Show (01:43:53) Coming Next Episode (01:52:42) Closing Have you wondered what it would be like if all the AI chatbots got together for a therapy session? Well, someone made it happen at the University of Luxembourg where researchers decided to put ChatGPT, Claude, Gemini, & Grok on the couch. My Insane FL Nephew, "Pancho Guero", has the details on just how intrusive screens are getting...in the bedroom. And there's now a "natural" replacement for Botox to use in boobs and butts...and it's fat from a dead stranger. Can things get more stupid. Yes. Yes, they can. And it ends up on this podcast.In this Weekend Episode...[A Piece of My Mind…] America Is In The Grips Of A Dystopian “Bill Maher Disorder”Man Jailed for Murder Goes Viral After Worrying He'd Miss Video GTA 6 ReleaseChatbots Were Sent to Therapy and THIS What Came Out⅓ of College Students Scroll Phones While 'Getting Busy'FDA Recalls “Horny” Honey—Because It's Loaded with CialisOlympic Officials Investigate Penis Injection Doping Claims In Ski JumpingBooty From A Dead Person? Women Chasing the Perfect Body Are Pumping ‘Ethically Sourced' Cadaver Fat Into Boobs and ButtsA Man Will Be Charged After Sticking a World War One Bomb Up His ButtWe have a couple of relationship questions that "Pancho" will answer that might settle the dispute over whether a husband should know his wife's dress size and is a mom over-reacting to her ex's influence over their 6-y/o son wanting to get an earring. There's 5 challening Mindbenders in this week's Insane Game Show that "Pancho" will have to solve--can you solve them, too? Put your sanity to the test with all the stupidity in this week's wild episode!Become a supporter of this podcast: https://www.spreaker.com/podcast/insane-erik-lane-s-stupid-world--6486112/support.Real-time updates and story links are found on the TELEGRAM Channel at: https://t.me/InsaneErikLane  (Theme song courtesy of Randy Stonehill, ”It's A Great Big Stupid World”. Copyright ©1992 Stonehillian Music/Word Music/Twitchin' Vibes Music/ASCAP) Order your copy on the Wonderama CD from Amazon!This episode includes AI-generated content.

On this episode of Bounced From The Roadhouse:Special Guests in 4B: Jesse AllenFlannel DayUmbrellasAmy's ShoeMalia's Swollen Lymph NodeBrandon's Life Cialis HoneyChicken BananaMardi Gras in Deadwood7 Ways to Save MoneyCheepest Grocery StoresThat's a Great QuestionBreezy Johnson - Lindsay VonnOlympics CurlingQuestions? Comments? Leave us a message! 605-343-6161Don't forget to subscribe, leave us a review and some stars Hosted on Acast. See acast.com/privacy for more information.

Something feels off when Cialis suddenly stops working, and that moment can shake your confidence fast.Many men assume the medication failed, but the real reason is often hidden beneath the surface and quietly getting worse. This episode pulls back the curtain on erectile dysfunction and why it shows up long before bigger health issues are diagnosed.Tune in to learn what your body may be trying to tell you and why acting sooner matters.--------------Resources mentioned:Modern Man CribMediterranean DietGood Morning Wood Smoothie--------------Curious about how you can boost your bedroom game and build lasting confidence? Check out the course at getwoodnow.com and start your journey to feeling like yourself again!--------------If you enjoyed this episode and want to learn more and get more tips, subscribe to The Modern Man newsletter for exclusive content delivered straight to your inbox! https://dranne.co/themodernman--------------Follow Me On:InstagramTwitterFacebookTikTokYouTube--------------For all links and resources mentioned on the show and where to subscribe to the podcast, please visit https://truongrehab.com/cialis-not-working-erectile-dysfunction-causes--------------Want to regain control of your sex life? It's time to reverse the effects of ED on your life. Join the Modern Man Club and embark on your journey to complete recovery and community.--------------Reveal the FREE treatment most men ignore that solves thousands of erectile dysfunction cases every year, plus the 5 biggest mistakes you must avoid if you want to say goodbye to your ED. Uncover it all in my free eBook, available to download now.https://dranne.co/ebook

Tony taps out to Craig Collins. Today’s Popcorn Moment: Dems believe Voter ID is Jim Crow 2.0. Cialis laced Honey. Today on the Marketplace: Nipple shields. Savannah Guthrie pleads for the release of her missing motherSee omnystudio.com/listener for privacy information.

Anti ICE leftists enforcing borders. Iran talks salvaged. Tony's voice is shot, he's going to tap out. Thursday Music Moment on early. James Brown - Good Foot. Plainfield schools block walkouts. Tony taps out to Craig Collins. Today’s Popcorn Moment: Dems believe Voter ID is Jim Crow 2.0. Cialis laced Honey. Today on the Marketplace: Nipple shields. Savannah Guthrie pleads for the release of her missing mother. Plainfield schools block the walkouts. The dark forces behind these nationwide walkouts. Woman trapped in a carwash. Fox 5 NY reporter cursing report accidentally gets to air. Homan announces drawdown of forces in Minneapolis. Leftist cat ladies may have toxic plasmolysis. Dave & Busters is hiding 3-carat diamond rings worth $15K in their ‘human crane’ machines See omnystudio.com/listener for privacy information.

What's Something Your Spouse Does That Annoys You? | Cialis Found In Honey | There's Quite The Scandal Already At The Olympics | Super Bowl Prop Bets | Wild Fantasy Football League | Who Buys Peppermint Patties?

An ex-employee broke into a Little Caesars and started making and selling pizzas, High school basketball referee in Oklahoma ejected and entire section of fans, A bunch of honey is being recalled because in contains the ED drug Cialis

If you want a clear breakdown of your choices, download the ED Options Cheat Sheet with links and exclusive discounts here: https://www.taboototruth.com/ed-options-cheat-sheetIn this episode of Taboo To Truth, I talk honestly about erectile changes in midlife and beyond. I explain why ED happens, why it often starts with blood flow and heart health, and why silence and shame delay real solutions.I cover what most men are never told.Why Viagra and Cialis stop working for some menWhy guessing and self adjusting doses backfiresHow lifestyle shifts protect erections instead of punishing youWhat actually works when pills failThe truth about pumps, rings, shockwave therapy, hormones, injections, Botox, fillers, and implantsErectile dysfunction is not a moral failing. It's a health signal. And there is no stage where options disappear.In This Episode:0:00 Erectile changes are normal and treatable0:58 Why erections change with age2:05 Blood flow, heart health, and ED3:10 Why pills stop working4:05 Pumps and rings explained5:00 Shockwave therapy and hormones6:05 Injections, Botox, fillers, implants7:30 The real takeaway and next stepsWant a deeper look? Watch the full episode on YouTube for a more visual experience of today's discussion. This episode is best enjoyed on video—don't miss out!Karen Bigman, a Sexual Health Alliance Certified Sex Educator, Life, and Menopause Coach, tackles the often-taboo subject of sexuality with a straightforward and candid approach. We explore the intricacies of sex during perimenopause, post-menopause, and andropause, offering insights and support for all those experiencing these transformative phases.This podcast is not intended to give medical advice. Karen Bigman is not a medical professional. For any medical questions or issues, please visit your licensed medical provider.Looking for some fresh perspective on sex in midlife? You can find me here:Email: karen@taboototruth.comWebsite: https://www.taboototruth.com/Instagram: https://www.instagram.com/taboototruthYouTube: https://www.youtube.com/@taboototruthpodcastKaren Bigman, a Sexual Health Alliance Certified Sex Educator, Life, and Menopause Coach, tackles the often-taboo subject of sexuality with a straightforward and candid approach. We explore the intricacies of sex during perimenopause, post-menopause, and andropause, offering insights and support for all those experiencing these transformative phases.This podcast is not intended to give medical advice. Karen Bigman is not a medical professional. For any medical questions or issues, please visit your licensed medical provider.Looking for some fresh perspective on sex in midlife? You can find me here:Email: karen@taboototruth.comWebsite: https://www.taboototruth.com/Instagram:

The best-seller herbal supplements we're covering today are yohimbe & horny goat weed. They placed #30 and 31 on the list we're using for this sequence of episodes. These two are marketed & sought-after as “male aphrodisiacs”, “testosterone boosters”, and even “herbal Viagra”. While it's true that each can “help” with some forms and manifestations of erectile dysfunction, in the short term or “in the moment”, they cannot correct the underlying issues… and might even make them worse.They're also quite potent, energetically speaking: heating, drying, and tonifying to a high degree. These qualities are primarily derived from potent constituents such as yohimbine and icariin. Each herb also possesses a multitude of other constituents apart from those more famous ones, which means its actions are diverse and in some cases self-contradictory.There's also a very serious problem in the supplement market for these herbs, which is that these products are frequently contaminated or adulterated. Many cases of ‘herbal' supplements for ED have been found to contain pharmaceutical drugs. In other words, that “herbal Viagra” was actually just… Viagra. Of the two of these herbs, Epimedium is significantly safer – but to be honest, we don't advise people to work with either of these plants. Other methods of addressing the issue at hand are more successful and more permanent, starting with herbal work to improve circulation and emotional steadiness. That's perhaps not as exciting as “herbal Cialis”, but it's safer and more realistic!CLICK HERE FOR FULL SHOW NOTES & REFERENCESIt's worth emphasizing that the majority of cases of erectile dysfunction, and several other types of sexual dysfunction or performance issues, are attributable to circulatory issues rather than hormonal imbalances. If you're looking for herbs to help with this trouble, and to address circulatory, blood, and heart health more broadly, then our course Cardiovascular Health is for you!Like all our offerings, this online video course comes with free access to twice-weekly live Q&A sessions with us, lifetime access to current & future course material, open discussion threads integrated in each lesson, an active student community, study guides, quizzes & capstone assignments, and more.If you have a moment, it would help us a lot if you could subscribe, rate, & review our podcast wherever you listen. This helps others find us more easily. Thank you!!Our theme music is “Wings” by Nicolai Heidlas.Support the showYou can find all of our online herbalism courses at online.commonwealthherbs.com!

The holiday season is here and in today's episode we are talking about giving and receiving gifts in your relationship. What does this ritual mean to you and which are you more comfortable with? George and Laurie share their thoughts and some of their favorite gifts and memories over the years. Laurie suggests that partners keep a running list of their loved ones' likes so when it comes time to get a gift you already have ideas handy. It's best if gifts are thoughtful and have your partner feel seen rather than buying something just because. Intentional gift-giving can spark connection and provide lasting memories. On the other hand, gifts that don't consider your partner or create pressure can lead to a negative cycle. What is one holiday gift or ritual that makes you feel good and inspires connection? Share with us on our instagram page! We wish all our listeners a happy holiday season and thank you for your continued  support! We hope you continue to listen in the new year and celebrate as we transition to our new brand Brave Love, Great Sex! Keep it hot and ho, ho, ho, y'all! Check out this episode's sponsors (and help the pod!): RexMD.com -- Reliable, discrete ED support! RexMD offers a simple, private path to get ED meds like Viagra, Cialis, or generics. RexMD is giving up to 95% off during the holidays! Call them today. Uberlube.com -- Laurie's long-time favorite personal lubricant! Simply the best! Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, Dr. Kahn breaks down new research on erectile dysfunction (ED) as an early warning sign—a "canary in the coal mine"—for heart disease and cardiovascular events, including mortality. He also discusses the emerging role of endocrine-disrupting chemicals and highlights new findings suggesting that ED medications like Viagra and Cialis may reduce all-cause mortality and potentially lower the risk of dementia. Additional topics include the connection between sleep apnea and Parkinson's disease, how skipping breakfast may raise cholesterol levels, the impact of high-polyphenol diets on resting heart rate, tai chi for improving sleep, alternate-day fasting, updates on the Watchman device, and new approaches to treating carotid artery disease. This week, Dr. Kahn also highlights the Echo Flask—an elegant way to make hydrogen-rich water. You can order one at echowater.com for a discount.

Dr. Elliot called in to talk all about penis pumps, tech cock rings, nocturnal erections and a whole lot more. Tune in to hear all the details including how and why a man's nocturnal erections are a leading indicator of cardiovascular disease, why blood-flow data is key to men's sexual health, why just taking a “pill” isn't enough,  how and why he's now selling a penis pump along with his tech cock ring, the study that showed what a penis pump can actually do for erections, the study comparing his cock ring to Cialis and Viagra and what the results showed, the hundreds of thousands of erections he's tracked with his cock ring and how it's helped men who use it, what the pump he's selling can and will do, the supplement he recommends that helps with blood flow, the different types of cock rings he sells and what they all do, the Ring Mate add-on that can pleasure your wife while you're wearing it, the reviews he gets from not just patients but docs as well, how nocturnal erections tie into testosterone levels, plus a whole lot more. To see HOT pics of my female guests + hear anonymous confessions + get all the episodes early and AD FREE, join my Patreon! It's only $7 a month and you can cancel at any time. You can sign up here: ⁠⁠⁠https://www.patreon.com/StrictlyAnonymousPodcast⁠⁠⁠ and when you join, I'll throw in a complimentary link to my private Discord!  MY BOOK IS NOW OUT FOR PRE-ORDER!!!! Strictly Anonymous Confessions: Secret Sex Lives of Total Strangers. A bunch of short, super sexy, TRUE stories. GET YOUR COPY NOW: ⁠⁠⁠https://amzn.to/4i7hBCd⁠⁠⁠  To join SDC and get a FREE Trial! click here: ⁠⁠⁠https://www.sdc.com/?ref=37712⁠⁠⁠ or go to SDC.com and use my code 37712  Want to be on the show? Email me at ⁠⁠⁠strictlyanonymouspodcast@gmail.com⁠⁠⁠ or go to ⁠⁠⁠http://www.strictlyanonymouspodcast.com⁠⁠⁠ and click on "Be on the Show." Want to confess while remaining anonymous? Call the CONFESSIONS hotline at 347-420-3579. All voices are changed.  Sponsors:⁠⁠⁠⁠ ⁠⁠https://butterwellness.com/⁠⁠⁠⁠ — Use the code STRICTLY at checkout for 30% OFF your entire order⁠⁠⁠⁠⁠⁠ ⁠⁠https://bluechew.com⁠⁠⁠⁠ — Get your first month of the new Bluechew Max FREE! Use code: STRICTLYANON⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠https://brooklynbedding.com⁠⁠⁠⁠ — Use my promo code STRICTLY at checkout to get 30% off sitewide⁠⁠⁠⁠⁠⁠ ⁠https://www.quince.com/strictlyanon⁠⁠⁠ — For premium quality Quince clothing plus FREE shipping and 365 day returns! ⁠⁠⁠https://beducate.me/pd2536-anonymous⁠⁠⁠ — Use code ANONYMOUS69 to get 50% off your yearly pass plus a 14-day money-back guarantee⁠⁠⁠⁠ ⁠http://loadboost.com⁠⁠⁠ — To get 10% off LOAD Boost by VB Health use code: STRICTLY ⁠https://uberlube.com/discount/Strictly⁠⁠⁠ — Use code STRICTLY for 10% off Uberlube aka the BEST Lube EVER⁠⁠⁠⁠ ⁠https://shamelesscare.sjv.io/xLQ3Jv⁠⁠⁠ — To get $15 OFF your oxytocin products, STI panels and more, use code STRICTLY  Follow me! Instagram  ⁠⁠⁠https://www.instagram.com/strictanonymous/⁠⁠⁠ X ⁠⁠https://twitter.com/strictanonymous?lang=en⁠⁠⁠ Website  ⁠⁠⁠http://www.strictlyanonymouspodcast.com/⁠⁠ Everything else: ⁠https://linktr.ee/Strictlyanonymouspodcast⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Dave Rubin of "The Rubin Report" talks about Joe Rogan being shocked as Elon Musk explains how Gavin Newsom and the Democratic Party will use Prop 50, gerrymandering and the next census to rig how many seats they will get in Congress; Arnold Schwarzenegger using his appearance on "Real Time with Bill Maher" to point out how Gavin Newsom is lying to voters to trick them into supporting Prop 50; Elon Musk explaining to Joe Rogan why illegal immigrants are the real reason that Democrats have been dragging out the government shutdown; Donald Trump telling "60 Minutes" Norah O'Donnell why Democrats government shutdown gamble is about to blow up in their faces; the "All In Podcast's" Chamath Palihapitiya having a tense exchange with Pete Buttigieg over immigration policies under Donald Trump; George Clooney surprising the host of CBS Sunday Mornings by throwing Kamala Harris under the bus; "The Weekly Show's" Jon Stewart expressing his disbelief when Kamala Harris lied to his face about Joe Biden's health and ability to serve another term as president; "Diary of a CEO's" Steven Bartlett tricking Kamala Harris to make some brutally honest comments about how she felt betrayed by Joe Biden; and much more. Today's Sponsors: BlueChew - BlueChew is the original brand offering chewable tablets for better sex combining the active ingredients of Viagra and Cialis into ONE chewable. Try your first month of Blue Chew tablets FREE when you use promo code RUBIN. Go to: http://bluechew.com/ and use promo code RUBIN Harvest Right - Use a Harvest Right freeze dryer. It handles all the freezing, vacuum sealing, and drying automatically. You can build food security that is reliable, cost-effective, and actually delicious. Go to: http://harvestright.com/rubin for a Harvest Right Home Freeze Dryer. Wild Alaskan - Wild Alaskan Company is the best way to get wild-caught, perfectly portioned nutrient-dense seafood delivered directly to your door. 100% wild-caught: This means there are no antibiotics, GMOs, or additives. Get $35 off your first box of wild-caught, sustainable seafood—delivered right to your door. Go to: https://www.wildalaskan.com/RUBIN.  

Dave Rubin of “The Rubin Report” talks to former Australian Prime Minister Tony Abbott about his warning for Western nations that can't move past the dark parts of their past; Australia's political and cultural identity; the strength and resilience of Sydney as a global city; Australia's close alliance with the United States and recent agreements on nuclear submarines and critical minerals; the importance of preserving unity among English-speaking nations; the impact of cultural Marxism and the erosion of national pride; the need for effective immigration integration and “work for the dole” programs; Australia's historical relationship with Aboriginal communities; and much more. Today's Sponsors: BlueChew - BlueChew is the original brand offering chewable tablets for better sex combining the active ingredients of Viagra and Cialis into ONE chewable. Try your first month of Blue Chew tablets FREE when you use promo code RUBIN. Go to: http://bluechew.com/ and use promo code RUBIN Tax Network USA - If you owe back taxes or have unfiled returns, don't let the government take advantage of you. Whether you owe a few thousand or a few million, they can help you. Call 1(800)-958-1000 for a private, free consultation or Go to: https://tnusa.com/dave Noble Gold Investments - Whether you're looking to roll over an old 401(k) into a Gold IRA… or you want physical coins and bars delivered right to your home Noble Gold makes the process simple, safe, and stress-free. Download the free wealth protection kit and open a new qualified account and get a FREE 10-ounce Silver Flag Bar plus a Silver American Eagle Proof Coin. Go to http://DaveRubinGold.com  

Dave Rubin of “The Rubin Report” talks to Spencer Klavan and Shermichael Singleton about Dan Goldman being put on the spot by CNN's Abby Phillip and being forced to grudgingly admit that Donald Trump was able to achieve a peace deal between Israel and Hamas that Joe Biden couldn't come close to pulling off; John Fetterman angering his fellow Democrats with his praise of Donald Trump for negotiating a ceasefire between Israel and Hamas and supporting him for getting the Nobel Peace Prize; CNN's Dana Bash correcting Nancy Pelosi's lie live on-air about the Democratic Party not being responsible for the government shutdown; Bernie Sanders shocking CNN's Kaitlan Collins for doubling down his support of a government shutdown until Republicans cave in to giving healthcare to undocumented immigrants; Donald Trump publicly taunting Chuck Schumer for how multiple factions of the Democratic Party now blame him for creating a government shutdown that appears to be backfiring for Democrats; CNN's Erin Burnett attacking Kristi Noem for comparing Antifa to other well known terrorist groups; and much more. Today's Sponsors: Crypto.com - Trump Media just signed a massive $6.4 billion deal with Yorkville Acquisition Corp. and Crypto.com. This new company will be the largest publicly traded CRO holder out there. For more information, visit Yorkville Corporation's Public filings: https://www.sec.gov/Archives/edgar/data/1849635/000114036125032615/ef20054552_ex99-2.htm Go to https://crypto.com BlueChew - BlueChew is the original brand offering chewable tablets for better sex combining the active ingredients of Viagra and Cialis into ONE chewable. Try your first month of Blue Chew tablets FREE - just pay $5 shipping when you use promo code RUBIN. Go to: http://bluechew.com/ and use promo code RUBIN Perplexity AI - Use the Comet web browser, the new AI-web browser from Perplexity, that will completely change the way you are able to interact with your browser. Download Perplexity's new AI-web browser, Comet, by heading to: https://pplx.ai/RUBIN Plus, right now when you download Comet - you get a month of Rumble Premium for free!  

Dave Rubin of “The Rubin Report” talks about White House Press Secretary Karoline Leavitt telling Fox News' Kayleigh McEnany how Barack Obama distorted the facts behind the ABC's suspension of Jimmy Kimmel; and the “Real Time with Bill Maher” crowd giving a loud approval for Bill Maher's condemning of MSNBC's Matthew Dowd for his implying that Charlie Kirk was somehow partially responsible for his death. Dave also talks to Rumble CEO and founder Chris Pavlovski about Charlie Kirk's vital role as an early investor in Rumble, how Charlie helped pick their new headquarters, and Chris's take on what the media gets wrong about the suspension of Jimmy Kimmel, among other topics. Dave also does a special “ask me anything” question-and-answer session on a wide-ranging host of topics, answering questions from the Rubin Report Locals community. WATCH the MEMBER-EXCLUSIVE segment of the show here: https://rubinreport.locals.com/ Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ Today's Sponsors: BeBetterNow- If you or your partner is over 55 and dealing with bladder urgency, you know—it's more than just a minor inconvenience. Go to http://BeBetterNow.com and get 10% off your first order with code Rubin10. BlueChew - BlueChew is the original brand offering chewable tablets for better sex combining the active ingredients of Viagra and Cialis into ONE chewable. Try your first month of Blue Chew tablets FREE when you use promo code RUBIN. Go to: http://bluechew.com/ and use promo code RUBIN Balance of Nature - Make sure you are getting all the positive effects from a wide variety of fruits and vegetables. Rubin Report viewers get 35% off their first order plus a FREE Fiber & Spice supplement when you use Code RUBIN. Go to: http://balanceofnature.com/