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The Game Changers podcast celebrates those true pioneers in education who are building schools for tomorrow. In episode 199 (Part 3) of Game Changers, Phil Cummins joins in conversation with Martin Westwell! Martin was appointed Chief Executive of the Department for Education in April 2022, following a successful 4 years as Chief Executive of the SACE Board. Martin has worked extensively with education systems and other organisations in using evidence to inform policy, practice, innovation and impact in education. He was a Chief Investigator in the national Australian Research Council (ARC) Science of Learning Research Centre, and has worked with UNESCO using evidence to inform strategic planning of education in the Asia-Pacific region. In 2018, Martin received the prestigious Australian Council for Educational Leaders' (ACEL) Gold Medal, awarded for the most outstanding contribution to the study and practice of educational administration and leadership. In 2007 Martin and his family moved to South Australia where he took the position of inaugural Director of the Flinders Centre for Science Education in the 21st Century and then Strategic Professor in the Science of Learning at Flinders University. Martin completed his degree and PhD at Cambridge University and was a Research Fellow at Lincoln College, Oxford University in biological chemistry. The Game Changers podcast is produced by Evan Phillips supported by a School for tomorrow (aschoolfortomorrow.com), and powered by CIRCLE. The podcast is hosted on SoundCloud and distributed through Spotify, Google Podcasts, and Apple Podcasts. Please subscribe and tell your friends you like what you are hearing. You can contact us at gamechangers@circle.education, on Twitter and Instagram via @GameChangersPC, and you can also connect with Phil and Adriano via LinkedIn and Twitter. Let's go!
The Game Changers podcast celebrates those true pioneers in education who are building schools for tomorrow. In episode 199 (Part 2) of Game Changers, Phil Cummins joins in conversation with Martin Westwell! Martin was appointed Chief Executive of the Department for Education in April 2022, following a successful 4 years as Chief Executive of the SACE Board. Martin has worked extensively with education systems and other organisations in using evidence to inform policy, practice, innovation and impact in education. He was a Chief Investigator in the national Australian Research Council (ARC) Science of Learning Research Centre, and has worked with UNESCO using evidence to inform strategic planning of education in the Asia-Pacific region. In 2018, Martin received the prestigious Australian Council for Educational Leaders' (ACEL) Gold Medal, awarded for the most outstanding contribution to the study and practice of educational administration and leadership. In 2007 Martin and his family moved to South Australia where he took the position of inaugural Director of the Flinders Centre for Science Education in the 21st Century and then Strategic Professor in the Science of Learning at Flinders University. Martin completed his degree and PhD at Cambridge University and was a Research Fellow at Lincoln College, Oxford University in biological chemistry. The Game Changers podcast is produced by Evan Phillips supported by a School for tomorrow (aschoolfortomorrow.com), and powered by CIRCLE. The podcast is hosted on SoundCloud and distributed through Spotify, Google Podcasts, and Apple Podcasts. Please subscribe and tell your friends you like what you are hearing. You can contact us at gamechangers@circle.education, on Twitter and Instagram via @GameChangersPC, and you can also connect with Phil and Adriano via LinkedIn and Twitter. Let's go!
The Game Changers podcast celebrates those true pioneers in education who are building schools for tomorrow. In episode 199 (Part 1) of Game Changers, Phil Cummins joins in conversation with Martin Westwell! Martin was appointed Chief Executive of the Department for Education in April 2022, following a successful 4 years as Chief Executive of the SACE Board. Martin has worked extensively with education systems and other organisations in using evidence to inform policy, practice, innovation and impact in education. He was a Chief Investigator in the national Australian Research Council (ARC) Science of Learning Research Centre, and has worked with UNESCO using evidence to inform strategic planning of education in the Asia-Pacific region. In 2018, Martin received the prestigious Australian Council for Educational Leaders' (ACEL) Gold Medal, awarded for the most outstanding contribution to the study and practice of educational administration and leadership. In 2007 Martin and his family moved to South Australia where he took the position of inaugural Director of the Flinders Centre for Science Education in the 21st Century and then Strategic Professor in the Science of Learning at Flinders University. Martin completed his degree and PhD at Cambridge University and was a Research Fellow at Lincoln College, Oxford University in biological chemistry. The Game Changers podcast is produced by Evan Phillips supported by a School for tomorrow (aschoolfortomorrow.com), and powered by CIRCLE. The podcast is hosted on SoundCloud and distributed through Spotify, Google Podcasts, and Apple Podcasts. Please subscribe and tell your friends you like what you are hearing. You can contact us at gamechangers@circle.education, on Twitter and Instagram via @GameChangersPC, and you can also connect with Phil and Adriano via LinkedIn and Twitter. Let's go!
Marc Kapetan sits down with Chief Investigator at the Tulare County District Attorney's Office Lindy Gligorijevic. Gligorijevic talks to us about her experiences as an author and various appearances on TV programs. The former LAPD Detective known as “The Killer Closer” shares some jaw-dropping stories and deep insights on some of the most intense and complex cases imaginable. Please Like, Comment and Follow 'The Marc Kapetan Podcast' on all platforms: --- The Marc Kapetan Podcast is available on the KMJNOW app, Apple Podcasts, Spotify or wherever else you listen to podcasts. --- Kapetan Brothers Law | Website | Facebook | YouTube | - Everything KMJ KMJNOW App | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.
The Transport Accident Investigation Commission has found fatigue caused a cruise vessel to run aground near Crooked Arm in Doubtful Sound in January last year. TAIC's Chief Investigator of Accidents Naveen Kozhuppakalam spoke to Paddy Gower.
Psychiatrist and author Dr. Judith Joseph joins Lesley to unpack "high-functioning depression," a hidden struggle affecting many high achievers who seem successful externally yet feel emotionally exhausted inside. Discover why driven individuals often overlook signs of burnout, the surprising prevalence of anhedonia (lack of joy), and Dr. Joseph's practical framework—the Five Vs—for understanding and enhancing your personal happiness. If you have any questions about this episode or want to get some of the resources we mentioned, head over to LesleyLogan.co/podcast. If you have any comments or questions about the Be It pod shoot us a message at beit@lesleylogan.co.And as always, if you're enjoying the show please share it with someone who you think would enjoy it as well. It is your continued support that will help us continue to help others. Thank you so much! Never miss another show by subscribing at LesleyLogan.co/subscribe.In this episode you will learn about:How to spot signs of high-functioning depression and overcome anhedonia.Why your emotions, including joy and anhedonia, directly influence those around you.The role of trauma, people-pleasing, and over-functioning in our mental health.Dr. Judith's biopsychosocial model for understanding your own unique path to happiness.Easy ways to reduce burnout by shifting from constant "doing" to mindful "being."Episode References/Links:Dr. Judith Joseph Website - https://drjudithjoseph.comDr. Judith Joseph Instagram - https://www.instagram.com/drjudithjosephHigh Functioning Book by Dr. Judith Joseph - https://a.co/d/9sFHkQWAnhedonia Assessment Quiz - https://drjudithjoseph.com/anhedoniaquizGuided Meditation by Deepak Chopra - https://beitpod.com/deepakchopraGuest Bio:Judith Joseph MD, MBA, is a board-certified psychiatrist, researcher, and award winning content creator who specializes in mental health and trauma. She is chair of the women in medicine initiative at Columbia University Vagelos College of Physicians and Surgeons, clinical assistant professor in child and adolescent psychiatry at NYU Grossman School of Medicine and Chief Investigator at Manhattan Behavioral Medicine, New York City's Premier Clinical Research Site. Dr. Judith was awarded by the US House of Representatives with a 2023 Congress Proclamation Award for her social media advocacy and mental health research. In 2024 she was named a top 6 NAACP Mental Health Champion and a VeryWell Mind top 25 Thought leader. In 2024 She taught a Workplace Mental Health Course to The Executive Office Of The President of The United States of America. In addition to being a notable public speaker at prestigious institutions, Dr. Judith is a sought after on-air expert who has been featured on Oprah Daily's The Life You Want Series, Good Morning America, The Wendy Williams Show, Tamron Hall, Today Show, CNN News With Anderson Cooper, The Mel Robbins Podcast, and more. She recently received a 2020 and 2023 Share Care Award for her MedCircle series on PTSD and a Good Morning America investigative special on ADHD. Social media's favorite psychiatrist, Dr. Judith boasts more than 880,000 followers across platforms, a 30% increase in less than a year. Her Instagram, TikTok, Facebook, and YouTube videos receive more than 15 million views per month. If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser or Castbox. https://lovethepodcast.com/BITYSIDEALS! DEALS! DEALS! DEALS! https://onlinepilatesclasses.com/memberships/perks/#equipmentCheck out all our Preferred Vendors & Special Deals from Clair Sparrow, Sensate, Lyfefuel BeeKeeper's Naturals, Sauna Space, HigherDose, AG1 and ToeSox https://onlinepilatesclasses.com/memberships/perks/#equipmentBe in the know with all the workshops at OPC https://workshops.onlinepilatesclasses.com/lp-workshop-waitlistBe It Till You See It Podcast Survey https://pod.lesleylogan.co/be-it-podcasts-surveyBe a part of Lesley's Pilates Mentorship https://lesleylogan.co/elevate/FREE Ditching Busy Webinar https://ditchingbusy.com/Resources:· Watch the Be It Till You See It podcast on YouTube! https://www.youtube.com/channel/UCq08HES7xLMvVa3Fy5DR8-g· Lesley Logan website https://lesleylogan.co/· Be It Till You See It Podcast https://lesleylogan.co/podcast/· Online Pilates Classes by Lesley Logan https://onlinepilatesclasses.com/· Online Pilates Classes by Lesley Logan on YouTube https://www.youtube.com/channel/UCjogqXLnfyhS5VlU4rdzlnQ· Profitable Pilates https://profitablepilates.com/about/ Follow Us on Social Media:· Instagram https://www.instagram.com/lesley.logan/· The Be It Till You See It Podcast YouTube channel https://www.youtube.com/channel/UCq08HES7xLMvVa3Fy5DR8-g· Facebook https://www.facebook.com/llogan.pilates· LinkedIn https://www.linkedin.com/in/lesley-logan/· The OPC YouTube Channel https://www.youtube.com/@OnlinePilatesClasses Episode Transcript:Dr. Judith Joseph 0:00 I think the more you practice this, the more exposure you get to this, not only do you change, but the people around you change. I always say Anhedonia is contagious, but joy is contagious too.Lesley Logan 0:13 Welcome to the Be It Till You See It podcast where we talk about taking messy action, knowing that perfect is boring. I'm Lesley Logan, Pilates instructor and fitness business coach. I've trained thousands of people around the world and the number one thing I see stopping people from achieving anything is self-doubt. My friends, action brings clarity and it's the antidote to fear. Each week, my guest will bring bold, executable, intrinsic and targeted steps that you can use to put yourself first and Be It Till You See It. It's a practice, not a perfect. Let's get started.Lesley Logan 0:55 Ladies, and the few good men who listen, hi. This is amazing. This is exactly an episode I wanted to have since last fall. We had a whole topic on Anhedonia, and I got so many of you reaching , going oh my God, tell me more. So, I found an expert. Get your notebooks out. If you're driving, you'll hit, you'll, just listen, because you want to listen again, you're going to take some notes, and also you're going to want to get this book. So Dr Joseph's book is going to be out April 8th, and so you, normally, I don't preview that. I let you fall in love with her and then tell you, but I'm already in love. I'm going to make sure I get my hands on a copy of this book. So definitely check it out, but here, for you to get the help that you deserve and some amazing validation of who you are and what you're going through, here is Dr. Judith Joseph. Lesley Logan 1:40 All right, Be It babe. I am honored, truly. I heard about our guest today through one of my favorite people in this world, Amy Lavell, and so Dr. Judith Joseph is our guest today. She has a story to tell us, and also has done so much research, and I wanted her on the show because my high-functioning peeps, I see you, we keep talking about not being a perfectionist, not over committing, not do all this stuff, but I thought we'd have an expert come in and talk about the journey of what that does to us and how we can get out of it. So Dr. Judith Joseph, thanks for being here. Can you tell everyone who you are and what you rock at? Dr. Judith Joseph 2:12 Thank you so much, Lesley. I'm a board certified psychiatrist. I am based in New York City, and I am high-functioning. AF. All of my followers know it. I do a gazillion things on top of being a single mom. I run a lab, content creation, podcaster, author of my book High-Functioning, conducting the first ever study in the world on high-functioning depression, which is something that you know is not really recognized at all in medical literature. But I don't think the depression of our days is our grandma's depression. I think there's a whole new beast out there, and many of us don't even know that we're walking around with it. So I'm trying to demystify that and to bring useful tools to heal.Lesley Logan 2:56 Yeah, that's why I was so intrigued by you. Because what I hear all the time is like, well, I'm not depressed because I get up every day. I do 17 other things, but there's no joy in it. And so can we maybe, maybe take a step back and figure out, like, what is high-functioning depression, and what are the maybe some of the signs that we might be having it?Dr. Judith Joseph 3:15 Well, you said two really great things. You said, listen, we're still getting up. We're doing our stuff. It doesn't look like anything's wrong. And you also said something that's really key, that there's just no joy in it. And actually, the two are connected. So when you go to a doctor or therapist, they're going to pull out this bible of psychiatry called the DSM, and they're going to go through checklists. And according to the DSM, the bible of psychiatry, Diagnostic Statistical Manual, if you don't meet criteria for a lack of functioning or significant distress, but you have all these symptoms of depression, like sometimes you have poor concentration, poor sleep, feeling on edge. That's what we call psychomotor agitation or restlessness, low mood, anhedonia, which is a lack of joy and interest and pleasure in things that once used to light us up, but you don't meet that box of lack of functioning or significant distress. They're going to be like, well, you know, come back and see me when things are really falling apart. The problem with that is that there are tons of people out there who have these symptoms of depression but are still functioning and over functioning because they're the rock, right? They're the mom, they're the boss, they're the teacher, you know, they're the doctor, the nurse, that people depend on, so you can't fall apart. So how do they cope? They busy themselves. They people-please and, eventually, something's going to give either they physically burn out, they mentally burn out, they have a major depressive disorder where they actually do stop functioning. They medicate with substances or with alcohol or self-soothe by shopping too much and going broke, right? Something's gonna give. So why are we waiting for people to lose functioning to do something about this? Why aren't we preventing it? And that's where the research comes in.Lesley Logan 4:56 Oh my gosh. I think first of all, a bunch of people just were like, uh, I have all these things. That's me. I meet a lot of women who are doing all these things, and yet they don't have that joy, that anhedonia that you mentioned, and they try to get help, and the help is either medications that they don't need right now because they're not fully depressed, or they're being told to come back later, and that's so frustrating to not feel heard, and then you just keep doing because you're like, okay, well, maybe I need to do this other seven things. Maybe these things will be the thing that makes me feel better. So I know that people feel so seen, and also I really hope that this becomes the thing people can get diagnosed with, because in that bible, because it does feel like, as you said, this the depression we're having now is not from grandma, because it's true, I don't have children, but if I just were to take off for a week, my team could do a lot, but at some point I need to, like, show up, like the wheels don't spin without, you know, so , it does, it can feel like there's extra pressure on the women who are going through this. How did you get involved in this topic? Were you just seeing it as a bunch of people coming through, or is it something that you went through? Like, can you tell us a little about how you got intrigued by this? Dr. Judith Joseph 6:06 Yeah, actually, it was during 2020, I was given this talk from the same desk that I'm talking from right now, and it was a large hospital system, and it was April, and people didn't know what the pandemic was going to do. They, I mean, we didn't know anything then, and I was called in to really give people the tools to get through a tough time. And halfway through the talk, I realized, I think I'm depressed, but here I am at my desk with my gazillion degrees behind me, instructing doctors and nurses and healthcare professionals on how to heal. And I didn't even realize that I was depressed because I was a doer, you know, and I had this saying, are you a human doing, or are you a human being, right? And I think a lot of us, that's our coping mechanism, at least for me. I'm an immigrant. I come from scarcity. It was never an option of giving up. You had to, you know, if times are tough, you work harder. If you go through something like a breakup, then you just got to take on more tasks at work, you know. And a lot of us cope with our pain by busying ourselves by doing versus just being and feeling and over time that wears on you. And I found myself at that moment in time during this Zoom talk, having that epiphany, and then led me to wonder, how many people on the other side of the Zoom feel like me, because there are a lot of nurses, a lot of doctors in healthcare. Then I started looking into, you know, some I'm in Manhattan, so a lot of my clients are performers, and they went through a really hard time during the pandemic, being out of work, and then the strikes and all that. And many of them, even though they were feeling depressed, they couldn't show it. They had to mask it, because they have to perform. They have to light up a room. So I just started looking at all these different industries, moms, you know, who have to do so many things. They have to go to work, they have to take care of their jobs. They have to take care of their kids. All these people masking these symptoms and just not slowing down and doing instead of feeling and healing. And I just thought, I'm onto something. So I created a reel on socials in 2022 and it went viral. It's been seen over 10 million times around the world. And I had people reaching out to me from different countries saying, I have that. I have anhedonia. This is me. How did you know? Like people were joking, do you have a camera in my home? That's me. Lesley Logan 8:23 Yeah, yeah. Well, I mean, I like, as we're sitting here talking, we're two weeks into the new year, so the before, you're, you know, we're taking a few months before everyone's hearing this. And I have friends who are in LA. I lived in LA for 14 years, and, you know, I checked on my friends where I live, where I lived, is still there, because it's kind of in the total middle. And so they're still going to work. Their jobs still expect them to do the thing that they're supposed to do. So they're showing up and doing all the things, and I'm showing up doing all the things, and I'm kind of like, so do we, this is how we just, like handle everything now. We just like keep doing and I think part of it is like it feels normal. And a lot of times we, when there's tough times, we want to do the thing that feels normal, because we we don't want to experience the other thing. But I also think not a lot of us have the privilege in life to not keep doing when stuff is going on, so then you're kind of stuck. You have to keep going, because the world like you are, that's how you get paid, that's how you make a living, that's how all these, that's what people expect of you. And also, you know, there's this underlying currently you can't really deal with so it feels like what you're onto is something that will continue to be happening, but we need to be able to recognize it, so we can label it, so that we can actually go and address it, right? Because we can't just keep living like high functioning, you know, we can't just keep doing that depression. Dr. Judith Joseph 9:42 Yeah, you're absolutely right. I saw this meme, hilarious meme, where it was like, I told my mom I was depressed, and she said, boy, we broke. We don't got time for that, you know. And I thought it was so funny, because you're right when you go through hard times and you don't have the privilege to slow down or others depend on you even if you are economically sound, but others depend on you. You just don't feel like you have that privilege to slow down. You feel like, well, let me just do because that's what I've always done, but you're absolutely spot on, something's gonna give either your body breaks down. And I think that's why a lot of women have these autoimmune conditions, because women, particularly are like they just have so much on their plate. There's so much expected of them. They're not allowed to seem deflated because someone else is going to take your position. Someone's going to say you're on your period, or you're going through menopause. You know, there's just so much on our plates that we don't feel like we can slow down and certain under represented groups, same way, they're just happy to be in the room. Certain industries, doctors, like, if a doctor says that they are experiencing depression in certain hospital systems, they have to report it to the state. I mean, like, there are certain industries that you just can't even say that you're struggling. So I think that if we allow ourselves to process pain, it's not saying that we have to stop everything, because that's like the worst nightmare for someone who's had function AF. It's about teaching them how to get back into their body, how to process their trauma, so that once you start to feel the pain, then you can also feel the joy. But if you continue to numb and you keep on doing you're not going to be able to feel the pain, but you're also not gonna be able to feel the joys in life that we are all, you know, built to enjoy.Lesley Logan 11:28 That's so, thank you for sharing that. I think , like it's, to feel, I have a yoga teacher who is like, you cannot have one thing without the other. Like in the world, we want balance, you cannot have love in this world and not have hate. If you get rid of the hate, you get rid of the love. If you want to only have peace, there is war. Otherwise, you wouldn't know what you're in. And so if you want to have joy in your life, you do have to also feel your pain. And I think also not many of us were really raised on how to feel our pain. If I cried in public, it's like, hey, don't do that like you learn to mask it or bury it. And you brought up women with autoimmune issues. It is insane. How many women I know with multiple autoimmune issues, and you start to go, okay, what is going on here is either that we actually are testing for it, or the life that we're living now is causing us to harm our bodies in ways that are not visible, and not even things we would choose to do, but because we just keep shoving and not getting the help we need, or even if you're trying to get help, not being heard to get help. It's causing a lot of issues I feel like cannot be reversed, and we're missing out on a lot of life, you know. And you mentioned something about getting into your body that I love, because I'm a Pilates instructor, and I believe if you get into your body, you know so much about yourself. For the people listening, what are ways that you help people get in their body? What are the ways, the tools that you've used? Dr. Judith Joseph 12:49 Well, I love this Venn diagram called the biopsychosocial model, and I teach my patients. I teach my clients. It's three bubbles, if you can imagine them overlapping, but those three bubbles are a nice representation of each of us, and I always say your happiness is not the same as my happiness. Know the science of your happiness because a lot of people out there, they're trying all these different things, and it doesn't work for them, but that's because they're basing it off of the science of someone else's happiness. But there is only ever going to be one you. There's only ever going to be one Lesley, ever. I mean, when I think about that, I get chills, because it's like you're so unique. So understand what your makeup is. Understand your bio, which is basically your past history, in terms of your family history, your current medical conditions, what are the medicines you take? What are the supplements you take? You know? You have a very unique biology. Understand your psychology. That's the psycho part of the biopsychosocial you have traumas that are different than my traumas, right? You have resilience factors that are different than my resilience factors. You have a different attachment style, possibly to mine, right? Or different strengths or weaknesses psychologically. And then, the social aspect, we're just saying, I live in New York, you live in Vegas, there are different environmental factors there, right? You probably eat different foods than me, or we have different movement routines. You may have a different work environment than me, right? Understand your relationships. Those are all the social things. So we all have unique factors. And if we were taught to understand these overlapping diagrams, we would understand the science of our own happiness, and we wouldn't be chasing after someone else's happiness. That's number one. And knowing about the uniqueness of your happiness, if you're someone who tends to have a lot of pent up trauma in your body, then I could tell you to eat as much kale as possible, but that's not going to treat your trauma, right? So in that case, I'm going to focus on the psychology bubble of that Venn diagram, and I'm going to say, let's try and process that trauma. We may have to do some 5-4-3-2-1, exercises with you, or some more trauma-focused work, like EMDR work or trauma-focused therapy, making you feel safe again, because that's something that trauma survivors, you know, really grapple with that sense of safety and psychological safety, right? But if you're someone who, on the biological end of things, has an autoimmune condition, has headaches and really intolerable physiological symptoms, I'm not going to be like, well, let's put you in a trauma workshop, right? I'm going to say, let's work with your nutritionist, let's work with your movement specialist, let's work with your autoimmune doctor, and let's see if we can bring down the levels of inflammation, right? If the social issue is the problem, let's say you're in a toxic work environment, where every time you walk into work, you're triggered. Your heart is racing. You have broken self-esteem because people are like, not kind to you, and this is your job that you depend on for your livelihood. I'm not going to say, well, you know, let's have you go see your cardiologist. I'm going, to fix that fight or flight sensation in your chest, I'm going to say, it's your work environment. Let's see if we get you more support at work or get you out of that environment. So everyone has different factors going on, and I think that makes us really unique and special, but it also complicates things a bit further. So I wanted to democratize this tool that is taught in all of medicine and let everyone have access to it so they can understand their unique workup and areas that they should really focus on first and their step to understanding the science of their own happiness. Lesley Logan 16:24 I love that and I do see that there's a challenge there, because we are kind of trained that if you ask the question, you should get an answer, and that answer should help you. But it is true. You know, we all have different needs, especially, and at different times. And I love the idea of the three bubbles, because you can evaluate for yourself, oh, it is more of the psychos. That's where I need to go get help. It is more of this. But I do love like defining our own happiness, which is not easy if you never explored that, if that wasn't something that we were invited to do or even feel. And so I think that where I feel my listeners struggle, where I get a lot of questions, is almost like, how do they know if they're happy? How do they know? Because they're so busy doing and they might even feel like the pain of stuff that's going on, but they're having a really hard time feeling what's happy also, because I think as women, specifically, we sometimes feel bad if I'm happy and they're going through something, I should put things around so people can't see that I'm happy. I should bring my happiness. I should come down. So, I mean, is there tips on how to know what makes you happy? Dr. Judith Joseph 17:30 Yes, and that is why I have a happiness lab in New York City. And a lot of people don't know this, but happiness researchers, we very rarely use that word happy. People are like mind-boggled when they hear that, because a patientwho will come in to see me for private practice will say, all I want to do is be happy. And so I wear two hats. I wear the research hat and then the private practice hat, where I do traditional therapy and medication, but the research hat is really trying to understand whether or not this person's getting happy or worse, and we use points in research. And so I developed this scale, the Anhedonia Rating Scale. Anhedonia means a lack of joy and pleasure. So basically, you want to know how many points you're getting in these basic pleasures in life. If you have like, high anhedonia and you're not enjoying things, then that's a problem. I love to use these quantitative ways because unlike, you know, let's say diabetes, right? If you go on for diabetes tests, you know where your glucose is, you know where your hemoglobin A1C is. But with mental health, it's kind of harder, like you don't have a test where you can look at and say, oh, I'm getting happier, right? But these quantitative measures, these tests, are really helpful. So you can go on my website, take the Anhedonia Quiz and see if you're getting points of joy. Lesley Logan 18:44 You have a quiz? Dr. Judith Joseph 18:45 Yes, I have an Anhedonia Quiz on my website, and you can see whether or not you're getting points of joy in life. And then what I ask is that people practice the five V's, because that's based on the science of your happiness. So the five v's are, number one is validation. A lot of us with high functioning we're always pushing down our feelings if they're negative. We only talk about the good. We don't like to talk about the bad. Someone says, how you're doing, oh, I'm great, and your house could literally be burning down, and you're saying, great, you know? So I want people to start learning how to accept their emotions, whether they be negative or positive, and there are many tools that I give in my book on how to validate, because people have a hard time with validation. Number two is venting. How do you express your emotions? And there are ways to do healthy venting, but there are ways to engage in unhealthy venting. I do a lot of content on, you know, narcissistic parents, and a lot of us had parents who trauma dumped on us when it was not appropriate. So I talk about how to vent in an appropriate way and the different creative ways to vent. You mentioned crying. You know, crying is something that a lot of people don't engage in because they think from childhood they were told to stop crying, you know, like you're a cry baby. But crying is actually a very healthy way to express emotions. And when you cry and you let a good cry, your body calms down, you feel relaxed, you feel more connected to you. The third V is values. And I say that values are things that don't have price tags. They are things that are priceless. So tap into things that, you know what and when you think at the end of the day, your last minutes of life, you're not going to be like, I wish I had that Gucci bag. You're going to be like, I wish I had five minutes with my loved ones, or I wish I had 10 minutes to do something that I always wanted to do, you know? So tap into those values. Try to get part of those values once a day. For me, it's learning and sharing my knowledge with my daughter, so, like, I love to learn black history and science, and I teach her because she wants to be a scientist. That makes me feel great, or when I volunteer and I offer my expertise to underprivileged youth, because that was me at one point in life that makes me feel good, that, you know, that's a value that I'm going to be like, wow, I wish I could do. I wish I did more good in life, you know. And then the fourth is vital. So we only get one body and brain. We have to take care of it. And so, you know, that's probably a lot where you come in, in terms of understanding how to honor the mind-body connection, eating foods that decrease inflammation that are not processed, drinking enough water, getting sleep, you know, like putting that phone away and getting really rich sleep, getting movement that actually helps your longevity and makes you feel happier, and understanding how relationships can be very toxic. And I wish that this was taught in school when I was growing up, but a lot of people don't understand how negative relationships can really drain your life force, and then having that healthy work life balance that's all in the vitals. And then the fifth V is vision. How do you plan for joy in the future? And when I say a future, I don't mean like, 10 years from now. I mean like, as in an hour from now. So for example, after this podcast, I'm gonna have a nice dinner, probably curry or sushi, and I'm gonna eat it, not in front of a screen. I might watch a little bit of Emily in Paris, because that's my guilty pleasure. You know, like these are little points of joy that I'm gonna plan, to treat myself, because today I helped people. I talked with you, these are all things that I need to celebrate, but we don't celebrate but we don't celebrate that. We're like, well, we're supposed to be doing these things, you know, no, every time I get my daughter to school on time, I pat myself on the back, and I sit and I drink my coffee, my oat milk latte, and I take my time. I don't go straight to work. I go home. Take my time. It, 5, 10 minutes, and just say I did a good job. I got her to work. I got her to school on time today. These are all things that we can savor in life, but we rush, we're busy. We don't take the time. We don't treat ourselves like human beings. You know, how many times have you eaten in front of a screen and they're like, you can't even taste the food, you know, and you love the food, but you're like, did you enjoy that meal? Not really. I just needed to get rid of that hunger pain. So the five Vs can really help you to understand the science of your happiness. Once you do that Venn diagram, and then you apply the five Vs to your life, it can really make a difference and increase those little points of joy every day. Lesley Logan 23:11 I really love each one of those in a different way, also what I'm getting. I love that you introduced yourself as high functioning AF, because I do think that a lot of the people like myself and the people who listen to this podcast, we start to think like, maybe I should do less. If I just do less, then I'll be happier. But then we are not happier doing less, because we are people who want to do things, and we are high-functioning people we and so I loved that it's not necessarily about not doing stuff, it's about how you do stuff and how you acknowledge what you're doing. And I think that that's really special, because it's sort of going, going, going, it's like, yeah, pat, I got my kid, my daughter at school on time today. Way to go. Yes. We have an episode on Fridays here. It's called Fuck Yeah Friday. And just this year I changed it so, like, I share a story from Instagram or the internet that, like, inspired me, some woman who inspired me whatever she did. But then it's about sharing the wins from the listeners. So they send in a win, and sometimes they send in these wins, like I finally did, blah, blah, blah. And my favorite wins are, like, I actually made dinner for myself and I went to bed on time, and I'm like, yes, that's a win. That's a huge win. You know, we have to give ourselves credit for that, because, just because it's what you think you're supposed to be doing you not celebrating it is not going to help you enjoy doing it in the future, and it's not going to help you do it in the future. So I, those are my favorites, and so that's what the episode is about. It's about celebrating the things we did do, as opposed to like these achievements that we're waiting to celebrate until a certain time comes. I think that that is, it's hard to do. Most people can't see a win in something or a celebration in something that they're supposed to do. So thank you for highlighting that. Your book. You wrote a book. I think anyone who writes a book to get their word out into the world is amazing, because it's not the easiest thing to write a book. Who is the book for and what are you hoping they get from it?Dr. Judith Joseph 24:55 I'm glad you said that people who are high-functioning AF want to do everything, because five Vs is a lot. And I can personally say, and I say this in the book, pick one or two, because the rule of twos says you really shouldn't be working on more than one or two things at a time. But I like one and two. I like validation, because it's something we can all do. And I like venting a lot, like, sometimes I'll just be so exhausted, and I'm like, why am I so tired? I'm like, wait a second, I'm not practicing the five Vs. I validate, I acknowledge, actually, I am tired. I had a long day. And then I vent. Sometimes I say it out loud. Or I'll tell my partner, listen, I had a really busy day. Or I'll tell my daughter, I was like, oh, mommy, had a busy day, you know? Like, I then I really try. Or I'll, like, put something on Canva, on IG, and say I've had a rough day, or something like that, but I'm venting. I'm expressing. And the other things, you know, the values, I try to tap into at least something a little a day, you know, for my values, vitals, that's hard to get to. I don't work out every day. I try to, but it doesn't happen. But at least if I'm not going to work out, well, I'm going to eat well. And if I'm not going to eat well, I'm gonna sleep better or drink more water or limit my screen time. So, there's a temptation to want to do it all, but pick one or two and tap into it, and then score yourself and see if the anhedonia is getting better. And I really do believe that once you start to do these things that are not expensive, like these, are all things within your capacity, right, to democratize mental health, you can do these things, and your life will be happier. But this book is for that family member who never acknowledges how they're feeling when they struggle because they're the rock. The book is for that entrepreneur who really is afraid of bankruptcy, doesn't ever want to be in that position again, and overworks and overextends and doesn't enjoy their wins. It's for that mom out there who puts everyone before herself, who feels depleted but can't slow down because she feels empty and restless when she sits still she doesn't even know what makes her happy anymore. You know, it's for that immigrant student who feels as if everyone's dreams are on their back and they can't fail, they can't tell anyone that they're struggling, it really is for those people who wear a mask, like the educator, the teacher who spends all their money getting their students supplies, but doesn't even eat lunch, you know like you are seeing you matter, so take care of yourself, because there's no one else like you, and you're worthy of it.Lesley Logan 27:27 That is so beautiful, and I love that you can be in a different walk of life and this book is still for you, because there is, we all have these dreams and aspirations, and sometimes those are other people's dreams and aspirations on top of that, and it can just be a lot. I'm assuming the five Vs are in this book. If people want to, like, read and score and write notes, I do want to attach that I love, that you put values in there. It's something I really in this house, like, we like to all filter things through my, our values. And I'm like, that's a no, because it's not hitting one of these things, and I can't take on more than that. So I love that. And if it can fit one of these things, I could do it, but doesn't. But I never thought about, like, how to make sure I'm acting with that as a way of finding some joy. Because, yeah, that's really, really cool. And yes, I love that if you're not moving well, then eat well. And if you're not going to eat well, then you got to sleep well. You got to do something. You got to do something for your body. Yes. For you, you practice those five Vs because so in 2020 you felt like, okay, I must have this, like, high-functioning depression thing. Obviously, you worked your way through and this is where you're at, is this something that, as a high-functioning person, you might dip in and out of or you can start to recognize it. And the goal is, like you recognize it faster, so you don't go into the depression for too long before you get yourself out. Like, I guess what I'm asking is for my perfectionist is like, is this a light switch once we get over our shit, can we feel really awesome and we never have to go back? Or is this something that we gotta just monitor?Dr. Judith Joseph 28:55 I'm glad you said that, because one of the risk factors for this is something called people-pleasing. But people don't realize that people-pleasing is actually a watered down version of masochism. So before the term masochistic personality disorder was removed from the DSM, the bible of psychiatry, it was really a caricature of someone who sacrifices their own happiness for someone else's happiness, or who's constantly in a position of giving and not getting. And when people think of masochism, they think of sex. But it's not that type of masochism. It's the personality traits that makes people bend over backwards when they shouldn't be but they feel as if that's the only way right? These are doers. They do, do do but what ends up happening is that the takers, they don't, like, thank you. They're resentful of you. They're like, well, do everything because you wanted something, or did you think I wasn't capable? So it actually backfires. So falling into these traits of being a doer is a pattern. It's a way of life for so long but yeah, you're going to work on yourself, but there's going to be a time when you fall back, and I'm guilty of that too. I'm constantly oscillating. But when I start to practice the five Vs and I'm like, let me, like I just demonstrated, let me validate that I went through a hard day, let me acknowledge these feelings, it's easier for me to snap out of that downward spiral because I'm practicing these skills. And so I always explain happiness as when we think of happiness, we think of this picture in the future, like I finally got the job, or I finally got the clout, or I finally got the thing that I wanted, the person that I wanted, the home that I wanted. And then what research shows us is that when we get these things, we're still unhappy. We're on to the next right? So my philosophy has shifted to finding happiness in the now. So when I get into that slump where I'm like, looking around me and I'm like, oh, so and so is doing that, and I'm starting to feel low, and maybe I should be doing more, it's easier for me to snap back into my values, right? I acknowledge how I feel, I validate, I vent it, but then I also tap into my values. And I'm like, wait, but I don't value what they value. My values are different, and I'm pretty good right here, where I am, I'm pleased in what I value right now. So that allows me to slow down. And so I think the more you practice this, the more exposure you get to this. Not only do you change, but the people around you change. I always say anhedonia is contagious, but joy is contagious, too. If you've ever had a boss that was a micromanager who was doing everything and you all were like, oh my gosh, we're so busy, we're all burnt out. And if that something good happened to that boss, let's say they finally dated someone, or they finally got validation in life, or something happened and or maybe even they got ill and they realized this is not important. When that boss shifts, the organization shifts, right? An organization is only as good as its CEO. So I think that anhedonia is contagious, but so is joy. So when you start to shift inside, people are going to notice it. They're going to come towards you and be like something's different. I want what you have, and you may not be more successful, you may not have more money, you may not be more beautiful, but you have something that they want, and they're going to gravitate towards you, but you have to get it for yourself. They can't have what you have. And I really do think that people will start to cultivate joy within themselves by understanding the science of your happiness and applying your five Vs to your life. Lesley Logan 28:55 Oh my gosh. I feel like every woman has to get this book for their best friend, just even as preventative, even if your friend isn't going through this yet, it's true that anhedonia is contagious, and also so can that high function like the doing can be contagious too. So I really appreciate you. I feel like we could learn so much. Now I might have to just binge out on every video you make, but I can't wait to read the book when it comes out, and probably send it to 17 of my friends. So we're gonna take a brief break, though, and then find out where people can find you, follow you, work with you, get your book and then your Be It Action Items. Lesley Logan 32:58 All right, Dr. Judith, you truly have given us a wealth of knowledge. Where can people connect with you, get your book. Where do you like to hang out? Dr. Judith Joseph 33:06 So they can buy my book at drjudithjoseph.com or follow me on IG, Dr. Judith Joseph and all the socials they could find my book there. And if you order before the pub date, you get preorder bonuses, and I have courses on the science of your happiness and ways to take you through the five Vs. Lesley Logan 33:27 Oh my goodness. Thank you so much for bringing you. You really have given us a lot, the five Vs is amazing. So if that ends up being part of this Be It Action Items, that's totally fine with me, but something that caused this podcast to exist is I would be drawn to someone and love what they said, and then going, okay, like, what is my first next step, though, you know? And so the bold, executable, intrinsic or targeted steps people can take to be it till they see it. What do you have for us? Dr. Judith Joseph 33:51 I just recently did this guided meditation with Deepak Chopra, and he said something that I thought was profound. He just kept saying, lose your name and just say I am. And it's really like a part of the just be, you know, what is it to just be? And if you could just take five minutes a day just to feel your being, just to get to know yourself again, I think many of us have forgotten who we are. So if you could just be, you know, I say, be a human being, not a human doing, you could learn so much about yourself. That self-reflection time, you could practice the five V's during that time, you could just practice one, validation, right, and just be. It sounds simple, but I think it's very difficult for a lot of us to just be. Lesley Logan 34:40 To sit for five minutes is very difficult. And you guys, like, what I found is like, 30 minutes is only 2% of your day, so five minutes is, like, not even a half a percent. So I don't do math well, so don't correct me. But if we cannot take five minutes for our day, we really do have to re evaluate what we're doing and who we're doing it for, because that is not the easiest thing to just be for five minutes, but ooh, I sit in a cold plunge every morning for four minutes, four minutes. And here's why, my tub is not big enough for my whole body. So three minutes with like, shoulders, hips, stomach, ankles, and then a minute for the knees to go in. And what I can say is I don't want to do it before I get in. I step in and I'm like, why am I doing this? I get in, I'm like, the air is sucked out, and then within a few seconds, you kind of settle in, and you're like, I just have to be here for four minutes. This is all I have to do. And it really is something that I'm so grateful that I do every day, because it does let me, like, set to go okay, today is today. Here I am today. I'm not even thinking about the schedule. It's just kind of like this moment and just being in this moment, where am I feeling this and how am I doing? And I highly recommend it. You don't have to get a plunge, but it just sits still for five minutes and see how you're doing. I highly recommend. I love that Be It Action Item. I think it'll be a challenge for a lot of people, unfortunately, but also I hope it's one that they take on, because I do love that. Dr. Judith, you are fabulous. I hope to one day, run into you and see what you're doing changing this world, because I do think this, your book and what you're saying are really what people are needing to hear right now. And I also just want to highlight one more time, everything you said in those five Vs is not actually going to cost a lot of money. It's like things you can just do by evaluating and addressing. So I appreciate tips like that. So thank you being you. Lesley Logan 36:18 Y'all, how are you gonna use these tips in your life? Make sure you tag Dr. Judith, you tag the Be It Pod, share this with a friend, but this is a friend who needs to hear it, you know, sometimes we feel like we have to help everyone, and sometimes we can help them by sending Dr. Judith's words to them so that she can help them and you can go back to taking care of you. So thank you so much. And until next time, Be It Till You See It. Lesley Logan 36:39 That's all I got for this episode of the Be It Till You See It Podcast. One thing that would help both myself and future listeners is for you to rate the show and leave a review and follow or subscribe for free wherever you listen to your podcast. Also, make sure to introduce yourself over at the Be It Pod on Instagram. I would love to know more about you. Share this episode with whoever you think needs to hear it. Help us and others Be It Till You See It. Have an awesome day. Be It Till You See It is a production of The Bloom Podcast Network. If you want to leave us a message or a question that we might read on another episode, you can text us at +1-310-905-5534 or send a DM on Instagram @BeItPod.Brad Crowell 37:21 It's written, filmed, and recorded by your host, Lesley Logan, and me, Brad Crowell.Lesley Logan 37:27 It is transcribed, produced and edited by the epic team at Disenyo.co.Brad Crowell 37:31 Our theme music is by Ali at Apex Production Music and our branding by designer and artist, Gianfranco Cioffi.Lesley Logan 37:37 Special thanks to Melissa Solomon for creating our visuals.Brad Crowell 37:42 Also to Angelina Herico for adding all of our content to our website. And finally to Meridith Root for keeping us all on point and on time.Support this podcast at — https://redcircle.com/be-it-till-you-see-it/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
Subscribe to Bad Faith on Patreon to instantly unlock our full premium episode library: http://patreon.com/badfaithpodcast Grayzone U.K. Chief Investigator and Co-Founder of Active Measures Kit Klarenberg joins Bad Faith to talk about the impact of the new administration on the Ukraine-Russia war, recent developments in the field, and what the ultimate endgame is likely to be. Also, Kit speaks to the authoritarian crackdown on pro-Palestine speech from his personal experience being detained in the U.K. for his reporting on Ukraine. Subscribe to Bad Faith on YouTube for video of this episode. Find Bad Faith on Twitter (@badfaithpod) and Instagram (@badfaithpod). Produced by Armand Aviram. Theme by Nick Thorburn (@nickfromislands).
This important webinar is designed to equip health professionals and leaders with the tools, insights, and strategies to foster mental wellbeing in their teams during crises and beyond. This session will:* Present key research findings on healthcare workers' mental health needs during crises like COVID-19.* Introduce an insightful report and checklist as actionable resources for enhancing mental health support in healthcare settings.* Demonstrate how addressing mental health can strengthen teams and improve organisational outcomes.* Use compelling data to outline what needs to change and the steps leaders can take to drive improvement.* Empower healthcare leaders with clear, implementable recommendations for creating mentally healthy workplaces. Facilitator: Dr Peter Baldwin – Senior Research Fellow and Clinical Psychologist, Black Dog Institute | Co- Investigator, Future-Proofing the Frontline guide Panellists: Prof Natasha Smallwood – Respiratory Physician, Department of Respiratory & Sleep Medicine at The Alfred Hospital; Head Chronic Respiratory Disease Group and Respiratory Research Training Lead Respiratory Research @ The Alfred School of Translational Medicine, Monash University; and Chief Investigator, Future-Proofing the Frontline report Dr Bethan Richards – Chief Medical Wellness Officer / Director SLHD MDOK Centre | Rheumatologist, Co- Director Institute for Musculoskeletal Health, PhD Health ProfessionalJess Maher- Lived Experience Representative, endorsed enrolled nurse Future-Proofing the Frontline: Organisational strategies to support frontline healthcare workers and leaders during times of crisis, is a guide that brings together insights from diverse perspectives and multiple sources of data to understand the best organisational strategies for supporting the mental health of healthcare workers. The guide and Organisational Checklist are available here: https://www.blackdoginstitute.org.au/news/future-proofing-the-frontline/
This important webinar is designed to equip health professionals and leaders with the tools, insights, and strategies to foster mental wellbeing in their teams during crises and beyond. This session will:* Present key research findings on healthcare workers' mental health needs during crises like COVID-19.* Introduce an insightful report and checklist as actionable resources for enhancing mental health support in healthcare settings.* Demonstrate how addressing mental health can strengthen teams and improve organisational outcomes.* Use compelling data to outline what needs to change and the steps leaders can take to drive improvement.* Empower healthcare leaders with clear, implementable recommendations for creating mentally healthy workplaces. Facilitator: Dr Peter Baldwin – Senior Research Fellow and Clinical Psychologist, Black Dog Institute | Co- Investigator, Future-Proofing the Frontline guide Panellists: Prof Natasha Smallwood – Respiratory Physician, Department of Respiratory & Sleep Medicine at The Alfred Hospital; Head Chronic Respiratory Disease Group and Respiratory Research Training Lead Respiratory Research @ The Alfred School of Translational Medicine, Monash University; and Chief Investigator, Future-Proofing the Frontline report Dr Bethan Richards – Chief Medical Wellness Officer / Director SLHD MDOK Centre | Rheumatologist, Co- Director Institute for Musculoskeletal Health, PhD Health ProfessionalJess Maher- Lived Experience Representative, endorsed enrolled nurse Future-Proofing the Frontline: Organisational strategies to support frontline healthcare workers and leaders during times of crisis, is a guide that brings together insights from diverse perspectives and multiple sources of data to understand the best organisational strategies for supporting the mental health of healthcare workers. The guide and Organisational Checklist are available here: https://www.blackdoginstitute.org.au/news/future-proofing-the-frontline/
Recorded at Evidence Based Perioperative Medicine (EBPOM) in London last year this presentation is part of a series of talks given under the session heading: “Implementation – what works and what doesn't?”. This piece is part one of four, with two more presentations to come and then a fascinating panel discussion to conclude. This first session focuses on the implementation of clinical trials, covering research methodologies, clinical implementations, and their challenges, and looking at the lengthy process of translating medical discoveries into clinical practice, emphasizing the ethical obligation to disseminate trial results effectively. The under-representation of certain demographics in trials, the gap between research findings and clinical practice, and the need for better communication strategies is stressed alongside solutions, including training for researchers, involving key stakeholders from the start, and the role of funders in supporting effective dissemination and implementation of research findings. Our presenter is, Joyce Yeung, Professor of Anaesthesia and Critical Care Medicine at the University of Warwick. She is Theme Lead of the Emergency, Prehospital, Perioperative and Critical Care Trials group within Warwick Clinical Trials Unit. Clinically she holds appointments as a Consultant in Critical Care Medicine at University Hospital Birmingham NHS Foundation Trust. Joyce is Director of UK Perioperative Medicine Clinical Trials Network. She is joint Clinical Speciality Lead for Anaesthesia, Perioperative Medicine and Pain for West Midlands Comprehensive Research Network. She is also the Chair of Resuscitation Council UK Immediate Life Support Subcommittee and is a member of Scientific and Education Committee at European Resuscitation Council. She serves as expert systematic reviewer and International Liaison Committee on Resuscitation taskforce member. Joyce is Chief Investigator for a major grant examining the impact of volatile versus intravenous anaesthesia in non-cardiac surgery (VITAL trial). Her research interests are applied health research and clinical trials including improving perioperative patient outcomes, chronic pain, post-operative cognitive dysfunction, and resuscitation. For more information about EBPOM and the conferences they are organising this year please go to www.ebpom.org
Chief investigator at the SPCA Serving Erie County, Lindsey Wood on the seizure of 32 dogs from a Hamburg residence on Wednesday full 319 Thu, 13 Feb 2025 17:45:47 +0000 8jcppuwt1wu9afoQ37h9yXeecDWPyNYQ news,wben,hamburg,spca serving erie county WBEN Extras news,wben,hamburg,spca serving erie county Chief investigator at the SPCA Serving Erie County, Lindsey Wood on the seizure of 32 dogs from a Hamburg residence on Wednesday Archive of various reports and news events 2024 © 2021 Audacy, Inc. News
Paranormal Saloon welcomes Kenny Biddle Kenny Biddle is the Chief Investigator for the Committee for Skeptical Inquiry (CSI), and CSI Fellow. He is a former ghost hunter turned science enthusiast and skeptical activist. He routinely investigates various claims of the paranormal
In this episode, our guests discuss the potential of large-scale health datasets to transform research and improve patient outcomes and healthcare systems. Our guests also delve into the ethical, logistical, and technical challenges that come with these programmes. We hear how organisations such as UK Biobank, Our Future Health, and All of Us are collecting rich, diverse datasets, collaborating and actively working to ensure that these resources are accessible to researchers worldwide. Hosting this episode is Dr Natalie Banner, Director of Ethics at Genomics England. She is joined by Dr Raghib Ali, Chief Medical Officer and Chief Investigator at Our Future Health, Professor Naomi Allen, Professor of Epidemiology at the Nuffield Department of Population Health, University of Oxford, and Chief Scientist for UK Biobank, and Dr Andrea Ramírez, Chief Data Officer at the All of Us Research Program in the United States. "There are areas where academia and the NHS are very strong, and areas where industry is very strong, and by working together as we saw very good examples during the pandemic with the vaccine and diagnostic tests etc, that collaboration between the NHS and academia industry leads to much more rapid and wider benefits for our patients and hopefully in the future for the population as a whole in terms of early detection and prevention of disease." You can download the transcript or read it below. Natalie: Welcome to Behind the Genes Naomi: So, we talked to each other quite regularly. We have tried to learn from each other about the efficiencies of what to do and what not to do in how to run these large-scale studies efficiently. When you are trying to recruit and engage hundreds of thousands of participants, you need to do things very cost effectively. How to send out web-based questionnaires to individuals, how to collect biological samples, how the make the data easily accessible to researchers so they know exactly what data they are using. All of that we are learning from each other. You know, it is a work in progress all the time. In particular you know, how can we standardise our data so that researchers who are using all of us can then try and replicate their findings in a different population in the UK by using UK Biobank or Our Future Health. Natalie: My name is Natalie Banner, and I am Director of Ethics at Genomics England. On today's episode we will be discussing how we can unlock the potential of large health datasets. By that I mean bringing together data on a massive scale, including for example genomic, clinical, biometric, imaging, and other health information from hundreds and thousands of participants, and making it available in a secure way for a wide range of research purposes over a long time period. Through collaboration and industry partnerships, these programmes have the potential to transform research and deliver real world benefits for patients and health systems. But they also come with challenges ranging from issues in equity and ethics through to logistics, funding, and considerable technical complexities. If you enjoy today's episode, we would love your support. Please like, share, and rate us on wherever you listen to your podcasts. I'm delighted to be joined today by 3 fantastic experts to explore this topic. Dr Raghib Ali, Chief Medical Officer and Chief Investigator at Our Future Health. Professor Naomi Allen, Professor of Epidemiology at the Nuffield Department of Population Health, University of Oxford, and Chief Scientist for UK Biobank, and Dr Andrea Ramírez, Chief Data Officer at the All of Us Research Program in the United States. Andrea, if I could start with you. It would be really great to hear about All of Us, an incredibly ambitious programme in the US, and maybe some of the successes it has achieved so far. Andrea: Absolutely. Wonderful to be here with you and thank for you for the invitation. The All of Us Research Program started in 2016 from the Precision Medicine Initiative and was funded with the goal of recruiting 1 million or more participants into a health database. That includes information not only from things like biospecimens including their whole genome sequence, but also surveys that participants provide, and importantly linking electronic health record information and other public data that is available, to create a large database that researchers that access and use to study precision health. We have recruited over 830,000 participants to date and are currently sharing available data on over 600,000. So, we're excited to be with your audience, and I hope we can learn more and contribute to educating people listening about precision medicine. Natalie: Thank you, Andrea. And not that this is competitive at all, but Raghib, as we are recording this, I understand the Our Future Health programme is marking quite a phenomenal milestone of 1 million participants. Would you mind telling us a little bit about the programme and something that you see as the benefits of working at scale for health research. Raghib: Thank you very much. So, Our Future Health is a relatively new project. It was launched in 2020 with the aim of understanding better ways to detect disease as early as possible, predict disease, and intervene early to prevent common chronic diseases. Similar to All of Us, we are creating a very large database of participants who contribute their questionnaire data, physical data, genetic data, and linkage to healthcare records, with the aim as I said, to really improve our understanding of how best to prevent common chronic diseases. So, we launched recruitment in October 2022. Our aim is to recruit 5 million participants altogether, and in the last 2 years about 1.85 million people have now consented to join the project. But you are right, as of last week we have what we call 1 million full participants, so people that have donated a blood sample, completed the questionnaire, and consented to link to their healthcare records. In our trusted research environment, we now have data on over 1million people available for researchers to use. Of course, we have learnt a lot from the approach of UK Biobank, which we are going to hear about shortly, but the resource is open to researchers across the world, from academia, from the NHS, from industry, so that will hopefully maximise the benefits of that data to researchers, but as I say with a particular focus on early detection, early intervention, and prevention research. Natalie: Thank you Raghib. Great to have you with us. Naomi, Raghib mentioned that UK Biobank has been running for a long time, since 2006. It is a real success story in terms of driving a huge range of valuable research efforts. Could you talk to us a little bit about the study and its history and what you have learned so far about the sort of benefits and some of the challenges of being able to bring lots of different datatypes together for research purposes? Naomi: Yeah, sure. So, UK Biobank started recruiting 0.5 million participants in 2006 to 2010 from all across the UK with a view to generating a very deep dataset. So, we have collected information on their lifestyle, a whole range of physical measures. We collected biological samples, so we have data on their genomics and other biomarkers. Crucially because they recruited 15+ years ago, we have been able to follow up their health over time to find out what happens to their health by linkage to electronic healthcare records. So, we already have 8,000 women with breast cancer in the resource, cardiovascular disease, diabetes, and so on. But perhaps most importantly, not only does it have great data depth, and data breadth, and the longitudinal aspect, is the data is easily accessible to researchers both from academia and industry, and we already have 18,000 researchers actively using the data as we speak, and over 12,000 publications already generating scientific discoveries from the resource. Natalie: So, we have got 3 quite different approaches. Recruiting in different ways, different scale, different depth of data collection and analysis, but all very much around this ethos of bringing lots of different datatypes together for research purposes. I wonder if you could talk a little bit about how you might be sort of working together, even though you have got slightly different approaches. Are there things that you are learning from one another, from these different data infrastructures, or how might you be looking in the future to work together to address some of the challenges that might come up from working at scale? Naomi: So, we talk to each other quite regularly. We have tried to learn from each other about the efficiencies of what to do and what not to do in how to run these large-scale studies efficiently. When you are trying to recruit and engage hundreds of thousands of participants, you need to do things very cost effectively. How to send out web-based questionnaires to individuals, how to collect biological samples, how to make the data easily accessible to researchers so they know exactly what data they are using. All of that we are learning from each other, and you know it is a work in progress all the time. In particular, how can we standardise our data so that researchers who say are using All of Us can then try and replicate their findings in a different population in the UK by using UK Biobank or Our Future Health. So, can we come up with common standards so that researchers can better directly compare the data that they are using? So, we are in close contact with each other. Natalie: Fantastic, thank you. And Andrea, from your perspective obviously you are collecting data in the US. Are you finding ways of working internationally and with other infrastructures like Biobank and Our Future Health around things like data standards? It sounds like something simple, but I can imagine it is quite complex in practice. Andrea: Absolutely, and that dialogue and understanding and learning from each other both informally in meetings and talking as well through the published literature. So, all of these datasets are actively widely used, and seeing what is coming out in publications helps us know what researchers are doing with the data. And when you see different researchers either generating hypotheses from our datasets in a different way, or testing hypotheses differently, that helps us understand where some benefit might be added to our dataset or where we really may need to grow in a different direction to meet some other research needs. I think that every study design always struggles with that balance between knowing exactly what we want to study and therefore building very specific questions and very specific protocols, but also allowing for the knowledge that we don't really know all of the discovery we need to make and bringing in datapoints that will really generate those new hypotheses for the future. I think for our study in particular, UK Biobank has been so remarkable in this way, helping structure All of Us to be able to contact our participants like UK Biobank and say, “Hey, we didn't really know what we were going to get, but we have put all this wonderful data together and now we need to do a deeper dive.” So, the engagement and long-term return of those UK Biobank participants has really enriched our data, and we have learnt from UK Biobank a lot there, and hope through growing our partnerships programme that we can continue to create partnered research opportunities to strengthen that data as well. That is a new thing coming out of our group. You may have heard of it previously as ancillary studies, but we recognise the partnership that is important for those research opportunities. So, we are reporting here that we are hoping to rebrand it to reach a larger audience, and that is led by Dr. Shelley, as partnered research opportunities that will allow us to re-contact, bring our participants back, and really deepen that dataset. Natalie: Thank you. And Raghib, I know that it is a really important part of the Our Future Health model about going back to participants, but you are in quite early stages of working out what those opportunities might look like. Raghib: Yes, very much early stages. Just to reiterate the point for me personally, having started my research in the UK about 20 years ago, I have certainly learnt a lot personally, but we have all learnt a lot from the model that UK Biobank established in terms of collecting data and providing it to researchers, and I see these 3 studies as very much complimentary. All of Us again have done a lot more work in terms of providing feedback to participants about their risk of disease and genetic information, and as you say Our Future Health was set up deliberately to not just be a purely observational study, but to give participants feedback about their risk of different chronic diseases as well as the opportunity to take part in not just studies to collect data, but also interventional studies to see if we can change the natural history of disease and prevent diseases in our participants. So, that has never really been done at scale before, and that is certainly a big challenge for us to do, not just in the UK, but anywhere, including the US and working with health systems as to how best to do that. So, you know we have spent the last 2 years really trying to understand how best to recruit participants and to provide data to researchers for the next couple of years, and long beyond that we will be looking really as to how we can maximise the benefits of providing feedback to participants and taking part in interventional studies. Naomi: I think one way in which we can all learn from each other actually, is we know how to recruit hundreds of thousands of people, the general population, into research study, and the next challenge is how do you keep engaging them, telling them what you are doing. You can't collect everything when they first join the study, or they would be with you for days. So, what UK Biobank has been doing is sending out web-based questionnaires, a couple a year, to find out extra information about health outcomes, lifestyle factors. Inviting them back to specific assessment centres. So, we are inviting 100,000 participants back for imaging, and then again over the next few years for a second scan. So, I think the real challenge here is once you have recruited them, how to find that right cadence of engaging those participants to keep contributing their data and their biological samples to really maximise the value of the dataset for research. That is an ongoing challenge for all of us. But I have to say, the UK Biobank participants, they are an amazing group of individuals, very altruistic. Our Future Health and All of Us, we don't give feedback, so there is nothing in it for our participants other than knowing that their data may help the future health of their children, and their grandchildren, and the rest of the world. So, that is very humbling, to know that the data that they have generated, and we have collected on them, is being used in that way. Natalie: That's a really interesting point, Naomi, about the difference between a research study that is designed for answering a particular question. You gather specific data for a specific purpose, and when it comes to recruiting participants into that you can be very clear about what it is you are trying to do. But of course, for all of these programmes, the whole nature of them is that you are collecting a lot of data over a long period of time, and it could be used for all sorts of different purposes. You can't say at the outset exactly what those purposes might be and what those outcomes might be. So, there is a really interesting question, and of course I would say this with my ethics hat on, a really interesting question around sort of participant trust and confidence in those programmes. Naomi, you spoke just then about one way of retaining engagement and retaining people's interest, but I wonder Raghib and Andrea, if you have got thoughts on those sort of questions of how you can create that environment where participants can trust what you are doing with data over a long period of time, when you can't at the point at which they consent, say exactly how that data might be used? You have got a sense of the kinds of purposes, but you can't be too specific Andrea: Sure. We know, and I have learnt from my own peers in this role, that enrolment in the study isn't the end point of engagement. All of Us's approach on engagement has been communicating with the entire community and really being there in the community, and that has been very powerful. One effort over the last year we are proud of has been what we are dubbing participant driven enquiry, and that is where we say, “Thank you participants. We have gotten a ton of data out there for use, and funded researchers to use it all the time, but what do you, the participants, really want?” We were able to then take papers that researchers write and help tell participants and explain it in lay language, so the participants can say, “Hey, I have a question. Could you answer that for me?” Maybe we can, maybe we can't, but it has been very interesting to hear what participants want to know, and that participant driven enquiry project has turned out to be a big opportunity there. The question they came to was not easy. Certainly, we didn't expect an easy question, but they came to us asking, “Why is my diabetes worse than someone else's? Is it the environment? Is it my genome? Is it my access to care? Why can't my diabetes be as well controlled as someone else's?” So, that has been huge, to interact directly with our participants and help really close the loop by answering questions in the language of research and show them how their data is contributing back. Natalie: Thank you. And Raghib, how are you sort of grappling with these questions, particularly because you are recruiting so very heavily at the moment? Raghib: So, as you say it is a challenge, and people do join the programme primarily based on trust that we will use their data for public health benefit and for the benefit of the whole population, but they also join on the basis that they will get back information about their own health and their risk of disease. To do both of those is not straightforward. I mean, the first of those, it has been well established by UK Biobank, and about 80% of our participants also say they are doing it primarily for to altruistic reasons, which is great. But 80% also said they would like to receive feedback about their own health, which is also understandable, and so we need to find ways to provide that in a timely way, but also in a way that the health service can manage. That is going to be one of our key challenges going forward. But to echo what Naomi and Andrea have said, I mean to maintain participant's engagement with the programme is not easy. We need to make sure that they are receiving information regularly, are kept up to date with what we are doing with their data, with the work that we are doing with academia, with the NHS, with industry etc. It is easier now than it was before because Our Future Health has been set up as a digital cohort, so we have means of communicating much more easily with our participants. But yeah, as you say we are at early stages. Over time that does get harder, to maintain that engagement. So, we know in the next one to 2 years we need to step up our work on feedback and recontact. Natalie: Fantastic. I really love the idea of like the participant-led enquiry. That is something that I think our participant panel at Genomics England would really like to hear more about. So, speaking about sort of ongoing engagement with participants, one of the challenges we know around recruiting into large-scale studies like this is that many research datasets don't have equal representation from all communities. That might have an impact on the quality, the representativeness of the scientific outputs that you can generate, and potentially the benefits back to patients and participants. How are you addressing this challenge in recruitment where you may have some communities that are not as engaged with scientific research. You may have elements of distrust or people being marginalised, having difficulty accessing research and these sorts of opportunities. Do you have any examples of what has worked really well? Raghib, if I could come to you first. Raghib: Sure. So, I mentioned I worked on UK Biobank about 20 years ago. One of the things I was looking at then was how we could maximise participation, particularly of people from ethnic minorities into the project. Because of the age group that was chosen by UK Biobank for very good reasons, age 40 to 69, the proportion of people from ethnic minorities was relatively small. So, although it was representative for that age group, I think it was about 6%, or 34,000 out of the 500,000, that were from non-white ethnic minorities. So, when Our Future Health was set up, we knew that the population has changed anyway. You know, the UK has become a much more ethnically diverse society. But also, because it is a cohort from 18+ and I think minorities tend to be younger on average than the white population, we knew we had an opportunity to really have a big step change in the number of people that could take part in a study like this. So, our aim is actually to get 10% of the whole cohort from ethnic minorities, so 500,000 out of the 5 million from ethnic minorities. Actually, so far we are pretty much on track. So, of the 1.8 million that have consented, about 180,000 are from non-white ethnic minorities. That is extremely important, particularly for genetic research where non-European populations are very much underrepresented in nearly all genetic databases. Secondly, from a UK context, although it applies of course in all countries, is that people from more deprived backgrounds are also less likely to take part in this type of research. So again, we have made a very deliberate attempt to try and ensure we have adequate numbers from the most deprived quintile. Again, about 10% of the cohort so far, nearly 200,000 are from that most deprived quintile who both are underrepresented in research, but also have the worst outcomes. So, this is really our first study that has been big enough in the UK to look at that group properly and understand some of the factors at an individual level that we haven't been able to in the past. Finally, geographically, so the first time again because it is a digital cohort, we were able to recruit people from all over the UK. So, every single part of the UK is now represented in Our Future Health, particularly coastal communities and rural areas that haven't been able to take part in this type of study before, as well as Northern Ireland. You know, for the first time we have got that full geographical coverage. Natalie: Fantastic. I suppose a lot of that recruitment approach has very much been about going to where people are, rather than expecting them to come to you. Is that right? Raghib: That is right and thank you for reminding me. So yeah, we have had a different approach. So, we have opened up many, many more clinics than previous studies through a combination of mobile units, shopping centres, community pharmacy. Community pharmacy in particular has been very important. So, to date we have had about 400 different venues that we have been able to recruit. That is over 1 million people that have given blood samples, and that has really enabled people from every part of the country to take part. Secondly, we have kept clinics open in areas of greater deprivation and ethnic diversity much longer than in other areas, to maximise the opportunity for them to join. Thirdly, we do provide reimbursement for people with expenses to ensure they aren't excluded because of financial reasons, and again that has helped. Natalie: So, really making those efforts is evidently paying off. Andrea, have you had similar experiences as All of Us? What has your approach been to try and ensure that you are getting a wider representation from different communities? Andrea: It has really been a focus on the programme from the start to engage those who have not been included in research in the past and make sure the opportunity is there to participate. Our Engagement Division, led by Dr. Corrine Watson has really pioneered reaching those communities here in the US. I think one other thing I will mention that we think about when we think about how to engage participants and reach people to return value back to those communities, is to make sure the people who are accessing the data also represent them, and we can build diversity within that researcher workforce. So, since our data was first released in 2020, we have recognised that the biomedical workforce also has a huge group of underrepresented individuals, and a lot of our researcher engagement and researcher outreach has focused on reaching those of diverse backgrounds and career paths. To that end we have reached out and engaged historically black colleges as well as other minority serving institutions, really looking to make sure that their students and researchers can have the same access as more traditional research-based institutions in the US system. That has been important because our system is built on cloud-based architecture and shared data that doesn't require a huge cluster on campus, and that helps remove a barrier that some of those institutions and researchers may have had. We also know they haven't been able to participate in the past, and we think that cloud architecture again can make the data much more feasible and be a huge support to diversifying the researcher workforce as we go forward. That circling back, helping them be the voices speaking to their community, helps build out that diverse participant community base as well. Natalie: That's such an important point, because it is not just about the participants and the data you can collect, but also who is able to look at it? Who is actually able to undertake the research? Naomi, can I bring you in here? I know that UK Biobank has been thinking a lot about researcher access to data and trying to ensure that the data that you hold, the really rich datasets you hold in UK Biobank, are more accessible to researchers from different backgrounds who may not have the same level of resources. Can you tell us a little bit about the work you have been doing on that? Naomi: Yeah. So, just following on from what Andrea said, it is really important to get as diverse ideas as possible from across the global research community to really move public health forward. So, what UK Biobank has done is we are putting mechanisms in place so that early career students, and career researchers, and researchers at all levels of their career from lower income countries, can access the data at a much lower fee. So, currently for most researchers it costs about £9,000 to access all of the data. So, that is 40 petabytes of genomic data, biomarkers, clinical outcomes, lifestyle factors and so on. So, early career researchers and those in lower income countries, it is about £500. On top of that a group of big pharmaceutical companies have got together to create a global researcher access fund, which essentially covers this reduced fee so that all researchers no matter where they are from have exactly the same opportunity to access the data to advanced scientific discoveries. So, on top of that all our researchers now use our online secure research analysis platform. While there is no charge to access the platform, there are costs associated with compute needed to analyse and store the results. So, AWS have donated research credits for early career researchers and those from lower income countries up to a total of about $500,000 per year, to use the research platform. So, researchers can apply to use these research credits to offset the costs of compute and storage. So, that means that we are trying to democratise access to researchers from all around the world. I think actually our biggest challenge is not so much … we have largely dealt with you know subsidising the cost. It is actually making researchers from lower income countries aware that these resources exist, and that are applicable to them. So, sometimes we hear from say researchers in Africa or South America, “Well, there is no point accessing UK Biobank because it is not relevant to our population.” You know, a third of our researchers are from China. So, even if UK Biobank hasn't got coverage of those racial ethnic populations, that doesn't mean that the associations that you find between risk factors and disease risk are not applicable to other different populations. And that is also why having different resources like UK Biobank, like Our Future Health, like All of Us, in different populations around the world, is so important in order to replicate those findings. Natalie: Absolutely, and fantastic just to hear the attention that is being paid to trying to ensure that diversity of different types of researchers who will just bring different questions to the table, different perspectives on the data, different priorities, different types of questions. So, speaking about that diversity of researchers, one really important part of his ecosystem that we haven't really touched on so far is around the role of industry. There are a lot of really important research questions being addressed by industry. Some that can only really come from, maybe it is pharmaceuticals, maybe it is tech. From your perspectives, what kind of role can and should industry and commercial partners play in supporting the kinds of long-term research studies that you have set up, and ultimately trying to get to that point of sort of generating benefits back to patients and health systems. Naomi, can I start with you, for that sort of longer-term perspective for Biobank? Naomi: So, industry are great partners for long-term studies like ours because they can bring additional funding, expertise, and technology. So, for UK Biobank, because it is so easily accessible to industry and academics alike on exactly the same terms, what it has meant is that industry, particularly big pharma and also now big tech, they can access the data, they see the value of the data for their own research purposes, and then they have invested into UK Biobank to do whole-exome sequencing, whole genome sequencing, proteomics at scale to increase the value of the dataset for their own drug discovery pipelines. But of course, it means that the data that they have generated, which cost millions of dollars to generate, when you need deep pockets to do these kinds of study enhancements, then become available to all researchers. So, having access to these large-scale resources that have deep data on genomics, physical measures, other biomarkers, and clinical outcomes enables pharma to rapidly increase their drug discovery pipelines in generating new drugs and treatments for patients, and also those data are then shared with the rest of the global research community. So, we found it to be a really exciting win/win in which industry get what they need to help move forward new drug targets and discovery, but also other researchers get what they need in order to make other scientific discoveries in different fields of research. Natalie: Thank you. And Raghib, I know that for Our Future Health, that industry relationship is a really important part of the founding model. Will you tell us a little bit about how you are engaging and working with industry partners? Raghib: Sure. So, as you said Our Future Health was set up in a different way, as a very public private partnership. Although the largest funder is the UK Government, more than half of our funding has come from a combination of life science companies, so pharmaceutical, diagnostic companies, as well as the medical charities, so the larger medical charities in the UK. That partnership is deliberate for all the reasons that Naomi has outlined. There are areas where academia and the NHS are very strong, and areas where industry is very strong, and by working together as we saw very good examples during the pandemic with the vaccine and diagnostic tests etc, that collaboration between the NHS and academia industry leads to much more rapid and wider benefits for our patients and hopefully in the future for the population as a whole in terms of early detection and prevention of disease. So, we have 16 life sciences companies that have joined as founding partners with Our Future Health who have contributed financially to the programme. Equally importantly they have also contributed scientifically, so there is a huge amount of scientific expertise in industry, and they work with us with our Scientific Advisory Board with our scientists internally to think about the best use of the resource for drug discovery, diagnostics, new medical technologies, and new targets etc. So, that is the vision, and so far, it is working well. It is a relatively new model to have set up a project like this in this way, but it has been a very collaborative approach, and we all recognise, all have similar aims, so recognise what we are working towards. You know, we meet regularly. We have a Joint Founders Board where as I say academia, NHS, industry, and the charities come together to decide on the priorities for the coming years. Natalie: Fantastic. And Andrea, I suppose in the US it might be slightly different culturally from the UK, but the role of industry with All of Us, how are you engaging with those pharmaceutical, technology bodies, and partners as well? Andrea: Absolutely, and maybe this goes back a bit to your first question. We at All of Us love learning from UK Biobank and have really seen them forge a lot of wonderful partnerships that have enriched and developed their dataset. We at All of Us have started with academia and working through partnership opportunities really intramurally at intramural centres that make up parts of the National Institute of Health. We believe that building on those close friends and family relationships we have both in the government and academia get us through our first step to be able to interface with commercial organisations. That really started with taking the first step this year to ensure broad availability of data that can maximise both use of the data available, as well as look forward to our partnership opportunities in the future. So, commercial organisations as of 2024 have also been able to access the All of Us dataset that is that first step in thinking about what a partnership would be, and we are glad to build on the access that international organisations and academic organisations already have. Natalie: A lot to look forward to here. We are going to have to wrap up in a moment, so I'd just like to leave you all with a final question before we have to end the podcast. There is huge ambition in all of the research programmes that you are leading and involved in, but what are you most excited about coming down the line in the next few years? What do you think is going to be feasible? What really gets you excited about the work that you are doing and where you see the potential benefits really landing in the next few years? Andrea, would you like to start? Andrea: Thanks. There is a lot we are really excited about. I haven't had a chance yet to mention our paediatric cohort, and that in addition to expanding access for international research, in 2024 we were able to enrol our first paediatric participants. That really sets up the potential to observe participants across the lifespan. That is a huge advance for All of Us and we are excited about the paediatric work going forward. Natalie: I love that, how do you come into the future with us? That is fantastic. Naomi. Naomi: Yeah, if I had to choose one would be the possibility of being able to measure circulating proteins on all half a million participants. We have done this on about 55,000 participants, and just that subset alone is already generating fascinating insights for early biomarkers for disease through protein profiles and risk prediction of disease. I think having that on all half a million coupled with their genomics data and health outcomes, will bring a sea change in how we diagnose disease earlier. So, I think that is a really exciting avenue for us to go into over the next couple of years. Natalie: Really enriching. That data sounds like a very exciting set of possibilities. Raghib. Raghib: Thank you. There are so many opportunities here, but I will just maybe mention 3. So, the first, in terms of being able to combine the genetic data that we are collecting and all the other information about risk factors, and particularly the fact that we have this on a lot of young people, will enable us to identify people at high risk of diseases in the presymptomatic phase and then to be able to offer them both feedback about their risk of disease but also interventions that can change their natural incidences. That has never really been possible before. That is extremely important for all diseases for people, but also it is very important for our healthcare system. So, those of you listening in the UK, I know the NHS is under a huge amount of pressure, and the current model of healthcare which has been in place really since the inception of the NHS, is to treat late-stage disease when people have already developed symptoms and signs. You know, it wasn't really possible to identify people earlier, but it is now, and Our Future Health will provide the evidence base to show that prevention really is better than cure, and to show that these approaches both lead to better clinical outcomes, but also are cost effective and a good use of resources. Of course, the new government is very much committed to this as well, you know moving from acute care to prevention, from hospitals to community, and from analogue to digital. Finally, because our cohort has now become so large and does cover every part of the UK, and this wasn't something I necessarily thought about when we started Our Future Health, we are able to have unique insights into the health of the population across every age group, across every ethnic group, across every geographical area, and by deprivation, and to understand not just observationally in terms of risk factors, but also the impact of interventions on those different populations. We can look at that, as I said at an individual level on millions of people to gain intelligence about what is going on in terms of public health, but also to see what will hopefully improve their health in the future. So, there are really, you know I have described transformational opportunities to improve health through both biomedical research and populational health insights now through the resource, and I look forward to working with colleagues across the UK and globally to deliver them. Natalie: We will wrap up there. Thank you so much to our guests, Dr Raghib Ali, Professor Naomi Allen, and Dr Andrea Ramírez for joining me today as we discussed how collaboration, scale, ongoing engagement, can really unlock the potential of large-scale health datasets to drive brilliant new research and ultimately improve the lives of patients and the population. If you would like to hear more like this, please subscribe to Behind the Genes on your favourite podcast app. Thank you for listening. I have been your host, Natalie Banner. This podcast was edited by Bill Griffin at Ventoux Digital and produced by Naimah Callachand.
The Genetic Rare Syndromes Observational Cohort (GenROC) study aims to improve our understanding of how rare genetic conditions affect the way children grow, their physical health and their development. Through actively involving parents as experts in their child's condition, the study seeks to gather valuable insights and ensure that family experiences shape future research and care strategies. You can find out more about the study and eligibility criteria via the Bristol University website. In this episode, Jillian Hastings Ward, patient advocate and former Chair of the Participant Panel at Genomics England, is joined by Dr Karen Low, a clinical geneticist leading the study at the University of Bristol, who shares insights into its objectives, the importance of a co-production approach with families, and the vital data being collected in the study to improve support for these children and their families. We'll also hear from Lindsay Randall, a parent who discusses the journey of receiving a rare diagnosis for her child, highlighting the critical need for more comprehensive information and community support. "If you join GenROC, that data will be used to develop a growth chart for your child essentially and their genetic condition, so I'm really excited about it because I feel like that's a very concrete definite given now for all the families in GenROC, which is just brilliant." You can download the transcript or read it below. Jillian: Welcome to Behind the Genes Lindsay: Historically, there's been a significant absence of patient voice in rare disease research and development, and knowing that's changing, I think that's really empowering for families and to know that professionals and industry are actually listening to our stories and unmet needs and really trying to understand, and that offers much greater impact on the care and treatments of patients in the future. Jillian: My name is Jillian Hastings-Ward. On today's episode I'm joined by Dr Karen Low, Consultant Clinical Geneticist and Chief Investigator for the General Cohort Study, and Lindsay Randall, Paediatric Practice Development Nurse and founder of Arthur's Quest, which is a UK registered, non-profit, raising awareness for the ultra-rare condition: SLC6A1, developmental and epileptic encephalopathy. Welcome to you both. Today we'll be discussing the GenROC study, which is aiming to understand more about the health, development and valuing the experiences of children with neurodevelopmental conditions. If you enjoy today's episode we'd love your support. Please like, share, and rate us on wherever you listen to your podcasts. Thank you both very much for joining us today, Karen and Lindsay. There's a lot we want to cover, but first of all it would be great just to put a little bit of context around the Gen-Roc study. Karen, can you tell us a bit about what the study is aiming to do, who is eligible and why do you want them? Karen: Thank you. And thank you so much for having me today, Jillian. So, the GenROC study, first to just explain to people what ‘GenROC' stands for. GenROC stands for the Genetic Rare Syndromes Observational Cohort Study. Just to give you some context about the study, I'm a clinical geneticist and most of my clinical work focuses on paediatrics, so I see children in my clinics and the sort of children I see generally are children with rare genetic syndromes. The last five to ten years we've got much better at diagnosing children with these rare conditions and that's because testing has got so much better. We can now do whole genome sequencing and we can do that on the NHS, which is amazing, children can get their tests as part of their clinical care, so it means that a lot more children are being diagnosed with rare conditions, about 2,000 per year in the UK. And the thing about that is, that I see these children in my clinics and I give their families that diagnosis. But the problem is for so many of these ultra-rare conditions, like Lindsay's family has, we sit there and we say to the family, “Well, your child has got ‘X' condition,” and we give them some information from maybe one or two publications and linked to a leaflet and a Facebook group. And then we say, “But really we don't know that much about this condition.” And they say, “But what is it going to mean for them when they are growing up or when they are adults? Will they be able to finish school? Will they be able to work? What is it going to mean?” And I have to shrug my shoulders and go, “I'm not really sure.” And as a geneticist and as a doctor and as a mother really, I just felt that wasn't good enough, and I found it really frustrating and I know that the families that I work with, that I look after, also find it frustrating and I wanted to do better. And I also found it frustrating that for many genes, researchers would publish two or maybe three publications about these conditions, and then they would move on to the next novel gene, and actually, the journals are a bit like that as well, they like novel things, they like new conditions, they like the next gene. And so, it means that actually data doesn't always carry on being gathered in these rare conditions, and there are a lot of them. That was another thing, I sort of felt that these conditions were being done a disservice and that we needed to do better, so that's where the whole idea of the GenROC study came from was my drive and desire to improve things for families and actually to work with families to improve that, and that's where so this is a very highly co-produced study and right from the outset I've involved parents in telling me what they wanted to know and I've got a very, very active PPI group, full of parents of children who have got rare genetic conditions, and also I'm really lucky to have a young adult who has a genetic neurodevelopmental disorder herself and they all tell me about essentially what I should do and what I shouldn't do. They tell me when I'm not doing enough or when I need to do something differently, so it's very highly co-produced, they're highly involved all along the way. So, children with a confirmed genetic diagnosis in a list of eligible genes which people can see on our website if they Google GenROC University of Bristol, we've got a very easy checker for eligible genes, but they are essentially the most frequently diagnosed genes in rare neurodevelopmental disorders. And if their child is under 16, has a confirmed diagnosis and doesn't have any other genetic diagnoses then they can go into the GenROC study, that's essentially the eligibility criteria. Jillian: That's really interesting. It's very helpful to hear the background and I think as a parent of a child with a very rare disorder hearing that the clinicians also recognise this gap and the sort of pause that happens once you have your initial diagnosis, is really helpful and really encouraging. Lindsay, can we turn to you next and can you unpack a little bit about what it meant for you to get a rare diagnosis for your child and what point on your family journey was that compared to where you are now? Lindsay: I think to get a rare diagnosis for us was difficult and challenging and I think the first kind of challenge that any family has is actually being well-informed by a paediatrician who is also well-informed, and that's not always the case. That can affect the way we acknowledge or accept a diagnosis and how we also access support and how we understand what more we can do to make more connections. We did have genetic counselling offered, but I think there are families out there who don't get genetic counselling offered to help them understand the child's diagnosis, and then there's a heavy reliance on the internet, and as you said, there's a lack of information out of there. A lot of conditions are newly diagnosed or they're very complicated genes to work with, or as Karen said, they've had a couple of papers and people have moved on. And I think that does cause an immense feeling of isolation. We were diagnosed in 2018, our son, our first child, and exactly as Karen said, it was a fairly quick appointment of, “We don't really know much about this condition at the moment, there's a couple of papers. We know of 34 children in the world at the moment with your condition. Here's a Facebook group,” which we did join. And it is overwhelming to be given a diagnosis that's delivered with such little hope I guess, finding sources of information that's valid and robust is challenging, not everyone knows how to do that or has a skillset to conduct searches of academic research and I think that clinicians could definitely do better in also signposting the kind of umbrella charities like Unique and Contact and Swan and patient organisations, because I know that would have been definitely helpful for us as a family to be able to have opportunities to connect with others. Jillian: Thank you. Our diagnostic journey has been a bit a similar in that we were diagnosed through the NHS, and that at the time my son was the first person diagnosed with his disorder in the whole of the UK so it was really a big question mark, it was a question of our geneticist saying, “Here's the three PDF articles that we know exist in the world about this condition. Can you read them and tell us whether you think that sounds like him in order for us to be confirming our diagnosis?” I very much hear what you're saying there about feeling lost in the wilderness. And we too joined a Facebook group quite shortly after we got our diagnosis, and at the time my son was among the older ones or certainly as time has gone by he has been among the older children, so it can be really hard to know what might happen next. I think that now as Karen was saying we're getting much better at diagnosing people thanks to all the extra testing that's happening, that happens much earlier in life than it has done in the past, but I think then it still leaves a gap in parents' understanding because you don't necessarily know what the next ten years might look like for example. And so, I think making connections with people who are in that age bracket can be really important, but it's very hard to do. So Lindsay, I'm conscious that your professional training as a nurse must have stood you in quite good stead when you were faced with a barrage of medical literature shortly after your diagnosis, but I think one thing that every parent shares is the desire to do the best for their child and especially in this world of rare disorders. There's a huge amount of energy that comes through the community I think, faced with the need to try and self-start and build these networks and connections for themselves. Is that something that you've seen in your community as your experience? Lindsay: Yes, definitely. I think we're a growing community and over the years of course more and more children and young adults have been diagnosed with a few older adults coming through. It is very much a global networking effort and parent/patient organisations have been set up in many countries now by parents of children with children with SLC6A1. I definitely think that drive to become an expert in your child's condition is a long journey and one of continual learning and actually a lot of families simply don't have a capacity to take that on, I think often the medical and scientific jargon is difficult to understand and that makes it challenging to access. And as you said, as a paediatric nurse, I at least have some existing skills to understand healthcare to read the research and speak with medical and scientific professionals with some confidence, but in some ways, that has increased the burden I've placed on myself to become an expert for my children and other children and families who are not in the same position as me. It does require a lot of dedication and time, and that does have implications on families because it's time away from our children and from home, and from the remnants of our lives that we desperately try to cling onto, to not lose all sense of ourselves. It's not often spoken about but I do see the strain it places on the families, as well where there's a lot of separation and divorce sadly in the rare disease communities, and often that's as a result of one parent's drive to be the expert, which seems to cause one parent to fulfil more burden of care and that fosters some level of resentment or sense of loneliness towards the other one. Jillian: There are some scary statistics out there around familial breakdown in this context, and it is something which there are so many factors at play, but it definitely seems to be quite widely recognised and definitely a problem. In terms of the time that people have to spend on liaisons with the research community and the clinical community, that could bring us quite nicely back into a question for you, Karen, about what kind of information the GenROC study is looking to collect from families, can you tell us a bit more about that, please? Karen: Yes, absolutely. As I said before, I've been very conscious of the sort of lives that our families are living, and listening to Lindsay, her story is very reminiscent of so many others and yours, Jillian. So I know families have about a gazillion hospital appointments, their children are often also very, very ill intermittently or a lot of the time, then they've got school stuff to deal with or they've got EHC plans to try and fight for. It's more than a fulltime job in itself just being a parent of a child with a rare disease and it's hard work, so me asking them to do anything else is asking a lot. Luckily, I find, with the families I work with, who are universally wonderful I should add, that they are actually just really enthusiastic anyway about research for their child's condition, and that's because there isn't enough information out there, so it's relevant and important to them. But because they have no time at all, and any time they do give is their own personal time when they could be finally putting their feet up and watching something on TV, I have to make it as low effort as possible. The questionnaire is all online, using a user-friendly and interface as we've been able to develop. It's very user-friendly, it takes 10-15 minutes to complete; they can come and go from the questionnaire as well. We only ask for one time point at the beginning, which is all the sort of stuff that most parents will be able to tell you off the top of their head as well, so they don't have to go looking for loads of information, apart from a height and a weight. Then later down the line we're going to ask for a second questionnaire, it's in the process of being finalised and again that will be the same amount of time, very easy to do, online, at their convenience. It was co-produced with the PPI group, they've tested it for me, I've had really good feedback and I've asked parents who are in the study as well for feedback. Everyone tells me it's not too difficult or burdensome for them to do. The secondary questionnaire has been very much informed by conversations with the parents that I had as part of a nest of qualitative interview study in GenROC, and that has driven that secondary questionnaire quite differently to what I thought it might be when we first set up the GenROC study. At the beginning I thought it might just be: have things changed for your child? Can you give us a bit more clinical data? But actually I realised that probably I will still gather that information, but they probably won't have changed that much within the timespan in the study because it will only be a year or two after they completed the first questionnaire, and actually I realised that it would be much more useful to look at the impact of the genetic diagnosis, look at how they're accessing services within the NHS, what sorts of services they are accessing, Impact on the family and also looking at priorities for families. So families have talked to me about what their priorities are in rare disease, both in service provision but also in research, and I really am a very strong believer that we need to be given the limited funding, we need to be doing the research that matters the most to the families, not to the researchers. What do families actually want us to look into? Actually, do they want us to be looking into behaviour and what strategies work best for example, rather than something else very medical – what matters the most? And so that's going to be a specific question in that secondary questionnaire, really trying to identify what matters to families the most and then how that can be translated into clinical research in the future. So I'm really interested to see what's going to come out of that. Lindsay: I think that sounds brilliant, Karen because I think historically there's been a significant kind of absence of patient voice in rare disease research and development, and knowing that that's changing, I think that's really empowering for families and to know that professionals and industry are actually listening to our stories and unmet needs, and really trying to understand, and that offers a much greater impact on the care and treatments for patients in the future and certainly it makes endpoints more relevant to families as well. Jillian: What kind of outputs are you going to be looking at? Karen: The height and weight, the reason I'm asking for that is really because we are trying to work on growth charts for children and that's because growth charts for children with rare conditions don't exist by enlarge, there are a very, very tiny number of rare syndromes or conditions that have their own growth chart. The problem is that most children with these sort of rare conditions that we're talking about are either quite small or quite big, and the problem is that the paediatricians look at their growth and they go, “Oh well, you're much bigger or much smaller than other children your own age, what shall we do about that?” and particularly the little tiny ones it causes lots and lots of concern, so quite often these sort of growth parameters mean that the paediatricians do lots and lots of tests or put feeding tubes down, or add lots of calories, so it can be quite invasive and interventional actually that sort of growth parameter. But actually, sometimes that's because of the genetic condition and no matter how much feeding you do it's not going to change anything. The difficulty is we don't know that for certain, and actually we need good growth charts where paediatricians can make that call, and conversely sometimes a child actually does need investigating and the paediatrician puts it all down to their genetic condition, and that's why we need these growth charts. So GenROC is aiming to gather growth data from all these children and then we're going to work closely with Decipher, which is a website that was developed through the DDD study, which already holds lots of data from that study, so we're building on the power of that study and we're going to be generating growth charts for all of these genes. We've developed a new method for producing growth charts for rare conditions where you've got small numbers of patients – that was never possible before, so we've already proven now for four conditions we can, so the next stage is using all the GenROC data, putting it into Decipher and coding it in. So, if you join GenROC, that data will be used to develop a growth chart for your child essentially and their genetic condition, so I'm really excited about it because I feel like that's a very concrete definite given now for all the families in GenROC, which is just brilliant. Jillian: And is that something which will be shared with the families individually? Karen: Really great question. I hadn't planned on sharing the growth charts individually with the families, but that's something I can also go back to my PPI group and discuss with them about whether that's something people would want, and also I have a newsletter which goes out every three months to the families, so I can certainly ask that question actually directly. It's going to be widely available, the growth charts, we're going to make sure that they're accessible to paediatricians and clinicians etc. but in terms of output to the study, definitely the growth charts, we're also hoping to have other clinically useful outcomes depending on the different genes that come into the study. We essentially have a cohort of children with rare conditions, everyone puts everything down to a specific genetic condition but we know that there must be other factors at play that influence how children do. And this is a really unique thing we're trying to do with GenROC actually, looking at aside from that genetic variant, that alteration, what other factors are influencing how children are doing? Because some of those might be modifiable, you know, or some of them there could be things that could be put in place to help improve outcomes. So I'm quite excited about that as well, because that's quite new and novel and not really been thought about in this context before, so that will be an output. And the other output is something that I'm working on with Unique, which is the rare disease charity who has worked with us on GenROC from the start, and they are involved in our PPI as well and that is going to be looking at a template, calling it a report at the moment, it's in very early days, but something that parents will be able to hold, it's going to have lots of drop-down boxes that can be tailored and modified for individual patients and children, which will be a bit of a guide that they can give to clinicians, professionals, education, telling them about their condition but also telling them on an individualised basis about what needs to be looked for in the future. Because parents tell me they are fed up of having to tell everybody about their child's condition constantly, all the time, over and over again. So what the point of this output would be is to try and ease that burden a little bit. This is very early stages but we're going to involved parents all along the way. Jillian: And is that something which builds on the hospital passport idea that we've seen emerging around the world over the last few years where parents can start off telling their child's story on their own behalf? Karen: So, it's come from my own lived personal experience of being a mother of a child with autism and I haven't really spoken about that publicly before, so it's something I'm saying for the first time. I have a child who has autism and I have had to navigate things like a DLA application form. Jillian: That's Disability Living Allowance. Karen: Yes, exactly, which is a horrendous form, it's the most horrible form to complete, probably apart from an EHCP plan form but it's a horrible form to complete, it's quite upsetting as a parent and it's also got millions of boxes that you have to fill in. But one of the things that really, really helped me when I was completing that was a charity who had come up with lots of drop-downs that you could select from that might be applicable to your child to help you complete this form. And so it made me really think, “Well, could we do something similar for our children with genetic conditions but come up with lots of dropdown options that might apply to their child in all sorts of different areas?” And that was the inspiration, it was that, and doing the qualitative study that I've already done with parents of children in GenROC who were telling me about how fed up they were of having to constantly tell everybody about their child's condition over and over again. Jillian: Yes, that's probably very helpful to empower families to use standard terminology across the different families because my own son has epilepsy as part of his condition but actually trying to describe what his seizures look like I'm not sure I'm using the right words to fit the right boxes to fit them into the right categories with the neurologist. So that level of standardisation is something that we definitely need embedded into the system in order for more people to be able to use this data more effectively, so that sounds very helpful. Lindsay, coming back to you, what are you hoping to get out of this study, or what are you hoping this study will do on your behalf for the world? What motivated you to take part? Lindsay: I think I would like to see all of the aims of the study realised and for the study data to be used to inform the development of standards of care for a wide range of conditions, those included in the study. I think it would be great if that information, as Karen said, is available not only to the participants but also to children diagnosed with those conditions in the future and also it's an opportunity to consider themes that are identified across the disease groups as that can also help inform future research and look at investigations into the mechanisms of disease and where actually therapeutics could treat maybe more than one disease at a time and increase potential for basket trials and early access programmes – thank you to Dr Karen Low and her team for conducting the project because it included a comprehensive list of rare diseases, it really does give parents and patients an opportunity to have a voice and to contribute, which is empowering, and it gives them a little bit of autonomy as well over their direction that science and research goes to. Jillian: Fantastic, thank you. Karen, can you tell us a little bit about the timeframe for the study? I realise that we haven't really touched on that so far. Karen: Yes absolutely, I'm aiming to recruit 500 children as a total. We're open at 22 sites across the UK. Coinciding with this podcast actually we've opened a second door for recruitment, so the way we've recruited so far has been through clinical genetic sites, which is the way we've done these sorts of studies in the past, like the DDD study. The problem is that that relies on clinicians identifying eligible patients and clinicians are very, very busy in the NHS. I have worked closely with Unique who have been doing a lot of publicity and the genetic alliance have done publicity as well for the study, so that's been one way of identifying eligible participants. And also just parent power through social media has been amazing. The second way we're going to recruit, and this is going to happen very soon, is through Genomics England. So, we are going to trial a completely novel way of recruiting to research through Genomics England and that is for Genomics England to identify eligible participants for GenROC and this would have been through the 100,000 genome study and then they're going to send them invite letters, inviting them to take part. So that's the next phase of recruitment, I think if we have more than 500 then that will be great too, we'll be able to include those comers too, so that's not a problem. But we don't know whether this will work or not in terms of a way of recruiting to research, this is completely new for Genomics England and I'm a bit of a guinea pig if you like through the GenROC study, but I was quite willing to be that guinea pig because I thought it might increase access. So there will be some parents who have not been told about GenROC who have not heard about it, and who would love to take part, so I feel like this is the way of really widening that net as wide as possible. Jillian: I think that is a challenge isn't it, especially in rare disease – there's no point doing a public broadcast about an initiative because you're going to hit so few of the people that you're interested in, so actually how you access the community is the first challenge and I'm really pleased that Genomics England will be able to help you there because I think that is a very useful route through. I think it will probably be quite reassuring to quite a lot of families who were on the 100,000 Genomes Project who have got a diagnosis of one of the conditions that you're interested in, and are now perhaps subsequently in the fallow period after you have a diagnosis, wondering what happens next, so I can imagine it might be quite good news for some of them at least that they are now being invited to do something further. And the reason that you're building forward and you don't want people who are currently in the deciphering developmental disorders study is because you're already using their data through another source, is that correct? Karen: Exactly. So absolutely, I don't want anyone to feel that I don't want them, that's really not the case. I do want them but we have their data already from Decipher, so we're building on the DDD data already, so they're already contributing which is just the beauty of it, because that's what we should be doing in rare disease, we should be building on previous research because you know, you don't want to be trying to reinvent the wheel. Jillian: Agreed. So if someone is listening to this and has a child with a rare developmental disorder and they are interested in finding out more, what are the steps they need to take? Karen: If they Google Bristol University, GenROC, they'll come straight to the webpage and everything is on there. There's a link that they can sign up, the patient information leaflet's there, the eligible gene list is there, all the information they need, including our email address. Jillian: And is there an upper age limit for recruitment? Karen: Yes, children have to be under 16 and that's because once they get to 16 many of these conditions have associated learning difficulties, and it's just very much more complex to try and recruit young adults, young people, with learning difficulties and given it was a cohort study we felt it was going to be too difficult at the moment. Saying that, I have a huge interest actually in how these conditions present in adulthood, and I'm actually conducting a much smaller study at the moment in KBG syndrome, looking at adults, and so I hope that my future research career will allow me both to follow-up the children in GenROC, so that would be my vision but also to be able to take this forward for other adults with rare conditions, that's my aim and goal in the medium to long-term, so watch this space for that. Jillian: That sounds very exciting, thank you. Lindsay: I think I would like to say to Karen that I really like the sound of the idea of following patients up into young adulthood and adulthood, as you said, that is definitely a kind of an unknown area in lots of the rare diseases, especially in our condition, SLC6A1, it was mutation and the disease was only really discovered in 2015, so it is fairly new and we have very, very few young people and adults coming through and being diagnosed and connecting with the rest of the community. So, being able to understand the trajectory of conditions better and especially conditions where actually the presentation it's quite a spectrum, and so the long-term outcomes for people with SLC6A1 can look quite different, so it's good to collate more information about that I think. Karen: I think it's really important, so that's definitely where I'm looking to for the future with GenROC and more widely, I think it's just something I'm really interested in and has huge relevance for parents and families. Jillian: Well, I think we need to wrap up there but thank you both very much Dr Karen Low and Lindsay Randall for joining me today as we've been discussing the GenROC study, and how the study aims to improve understanding of how rare genetic syndromes affect the way children grow, their physical health, their development, but also how the patient and parent communities can work more closely with researchers to end up delivering something which is of a huge benefit to everybody. If you would like to hear more about this, please subscribe to ‘Behind the Genes' on your favourite podcast app. Thank you for listening. I've been your host, Jillian Hastings Ward. This podcast was edited by Bill Griffin at Ventoux Digital and produced by Naimah Callachand.
Tom Hampson is an Air Force veteran, where he served as an Intelligence analyst in Western Europe. He also served as an Chief Investigator for the Illinois Legislative Investigating Commission and served on the Chicago Crime Commission as a board member. His work as an investigator prompted him to establish the Truth Alliance Foundation (TAF) and to dedicate the rest of his life to the protection of children. He hopes that the TAF will expand to facilitate the protection of children all over the United States and around the world.… Continue Reading
Cancer is a disease that will affect 1 in 5 people in our lifetime, and it's estimated that around 20 million people worldwide will be diagnosed with some form of cancer in 2025.But how might a vaccine help in the treatment of cancer?Numerous trials began testing the viability of cancer vaccines in 2024, including one for Melanoma and another for Lung Cancer. With all the promise that these new cancer vaccine trials bring for cancer patients, we explore the different ways in which vaccines could work within the body, and how the time at which future vaccines are administered may vary according to the cancers they are targeting.This week on the Inquiry we're asking: Are we close to a cancer vaccine?Presenter: Tanya Beckett Producer: Matt Toulson Researcher: Katie Morgan Production Coordinator: Tim Fernley Editor: Tara McDermott Studio Director: Craig Boardman Contributors: Meredith McKean, director of Melanoma and Skin Cancer Research for Sarah Cannon Research Institute at Tennessee OncologySamra Turajlic, Chief Investigator of translational studies into melanoma and kidney cancer at the Francis Crick Institute and Professor at the Institute of Cancer Research Eduardo Vilar-Sanchez, professor in the department of Clinical Cancer Prevention at The University of Texas MD Anderson Cancer CenterPatrick Ott, Clinical Director at Melanoma Disease Center at the Dana-Farber Institute
In hour 1 of The Mark Reardon Show's Best Segments of 2024, we present Mark interviewing Lauren Trager, the Chief Investigator from Channel 4 and Movie Reviewer Dan Buffa who discusses the 30 year anniversary of "Pulp Fiction". In hour 2, Sue hosts, "Sue's News". We then present Mark's interviews with Maureen Ferguson who discusses her concerns with children having access to the internet via cell phones and John Murawski who talks about civics courses in higher education. In hour 3, we present Mark's interviews with Gary Stromberg on the Rumble in the Jungle Music Festival, Jennifer Sey, and Tulsi Gabbard on her new book.
In hour 1 of The Mark Reardon Show's Best Segments of 2024, we present Mark interviewing Lauren Trager, the Chief Investigator from Channel 4 and Movie Reviewer Dan Buffa who discusses the 30 year anniversary of "Pulp Fiction".
In this episode, recorded live at Tactical Trauma 2024, Dr Claire Park explores the critical lessons learned from civilian and military incidents, focusing on her extensive experience in the Army and their role as chief investigator in a UK trial examining responses to terrorist attacks. The talk covers the significance of 'hot zones,' illustrated by detailed analyses of the London Bridge and Fishmongers' Hall attacks and key topics include risk assessment, the importance of rapid medical intervention, the concept of survivability, the need for integrated communication among emergency services, and the human factors influencing decision-making in high-pressure environments. Claire also delves into practical strategies like the 10-second triage and bridging interventions, emphasizing the need for timely and effective medical responses to save lives. 00:00 Introduction to Learning from Incidents 01:52 Setting the Scene: Hot Zones 01:55 Case Study: London Bridge Attack 04:23 Understanding Hot Zones 05:51 Case Study: Fishmongers Hall 07:58 Risk Assessment in Pre-Hospital Care 09:23 Communication and Coordination Challenges 10:16 International Models and Time Management 12:13 Triage and Life-Saving Interventions 15:18 Data and Research on Causes of Death 21:43 Human Factors in Emergency Response 24:00 Conclusion Dr Claire Park is a consultant in pre-hospital emergency medicine for London's HEMS, as well as anaesthesia and critical care medicine at Kings College Hospital in London. She also is an army consultant with over 20 years of deployed military experience. Claire is the Medical Adviser to the Specialist Firearms teams of the Metropolitan Police Service and has worked closely with all of the emergency services in London on developing the joint response to high-threat incidents, particularly following the attacks of 2017. She is the Chief Investigator on a UK nationally-funded research grant looking at evidence for improving patient outcomes in the hot zone of major incidents. She is also a CTECC Committee member.
Guest: Prof Dale Taylor |Associate Professor, Research areas: Physics Education, Research Education and Chief investigator at H3D In this context, the work of institutions like the H3D malaria research team is vital. Their research plays a pivotal role in developing new treatment options, understanding parasite resistance, and contributing to global malaria control strategies. To shed light on this, we're joined by Professor Dale Taylor, an Associate Professor with research expertise in Physics and Education, and the Chief Investigator at H3D. Professor Taylor is here to share insights on the landscape of malaria research and H3D's contributionsSee omnystudio.com/listener for privacy information.
Partners, Lian Skaf and Matt Ferrie, are back for the second part of their series titled, “Part 2: How to Make the Public Sector an Ally and not a ‘Public Enemy'.” John Lightbody, CFI, CFEI, CFII, Chief Investigator and President of Find The Cause Investigations, LLC, joins Lian and Matt to continue their discussion on subrogation professionals who work with the public sector in large-loss fire scene joint investigations. This episode also explores examples of claims going into litigation and provides case examples where the public and private sector investigators have a difference of opinion in the cause of the fire.
Listen to the newest episode of Subro Sessions, hosted by Lian Skaf and Matthew Ferrie, Partners at White and Williams, entitled, “How to Make the Public Sector an Ally and not a ‘Public Enemy'.” John Lightbody, CFI, CFEI, CFII, Chief Investigator and President of Find The Cause Investigations, LLC, joins Lian and Matt to talk about the best practices for subrogation professionals when working with the public sector during fire investigations including what to do on site, decorum, obtaining the proper investigation documentation and working with both federal and state agencies.
On this episode of IPA's What, Why & How podcast, Kate Gainer welcomes Anne Schlepphorst, Executive Director of the Iowa Board of Pharmacy, to discuss her many roles within the Department of Inspections, Appeals, & Licensing (DIAL), as well as the timeline for the new Board of Pharmacy rules pursuant to Governor Reynolds' Executive Order #10 and HF 555. Anne Schlepphorst serves as the Executive Director of the Iowa Board of Pharmacy, Interim Executive Director of the Iowa Board of Nursing, and Monitoring Bureau Chief. In addition to serving the Boards of Pharmacy and Nursing, Anne truly enjoys spending time working with staff to provide some of the best professional health programming in the country for health professionals struggling with mental health, substance abuse, and/or health-related impairments. Anne has worked with the boards for the past six years and was most recently the Chief Investigator for the Iowa Boards of Pharmacy and Medicine. When not working, Anne and her husband spend most of their time at the baseball field, hockey rink, wrestling mat, or football field watching their 10- and 14-year-old boys. Resources from today's episode: Published August 7: Iowa Administrative Bulletin: Regulatory Analysis – 481 Iowa Administrative Code Chapters 550-557 (new Iowa Board of Pharmacy rules, proposed) IPA's Iowa Pharmacy Law & Information Resource Center (LIRC) Connect with us on LinkedIn: Kate Gainer Anne Schlepphorst Iowa Pharmacy Association
Today, Host Patti Teel introduces Scam Squad's newest co-host, Chief Investigator, Christina Perkins , from the Bureau of Investigations at the Santa Barbara District Attorney's Office. Together, Patti and Inspector Perkin discuss the duties of the Investigators, as well as the latest scams currently affecting the Santa Barbara area and the nation in general. This week, Inspector Perkins alerts us to a recent scam called the, Hacking Scam, which has just started to plague our area. You won't want to miss this episode.
GUEST OVERVIEW: Mark Andrejevic is a Professor at the School of Media, Film, and Journalism at Monash University who contributes expertise in the social and cultural implications of data mining, and online monitoring. He writes about monitoring and data mining from a socio-cultural perspective, and is the author of three monographs and more than 60 academic articles and book chapters. He was the Chief Investigator for an ARC QEII Fellowship investigating public attitudes toward the collection of personal information online. Andrejevic has experience conducting both quantitative and qualitative research and is experienced in the focus group and interview methodologies. His work on the personal information project, for example, generated a book, 11 articles and book chapters, and a report on Australian attitudes toward online privacy that was launched by the Federal Privacy Commissioner.
On this episode of The Cybersecurity Defenders Podcast we sit down with Lee Sult, Chief Investigator at Binalyze, and talk about incident response (IR).Lee is a seasoned cybersecurity expert and investigator with extensive experience in digital forensics and incident response. He is the Chief Investigator at Binalyze and has a strong track record at prestigious organizations like Trustwave-SpiderLabs and Palantir. Lee has supported the US Secret Service and managed complex cybersecurity incidents for Fortune 50 companies.As the co-founder and former CTO of Horangi Cyber Security, Singapore's first cybersecurity startup, Lee's leadership and collaboration skills have significantly impacted the region's cybersecurity landscape. Passionate about mentoring, Lee actively contributes to cybersecurity communities and supports up-and-coming entrepreneurs.
Partnered with a Survivor: David Mandel and Ruth Stearns Mandel
Send us a Text Message.The recently published groundbreaking, population-based study of child maltreatment in Australia found exposure to domestic violence is the most common form of maltreatment (39.6%). In this interview with Professor Daryl Higgins, one of the studies' chief investigators, David and Ruth discuss the domestic violence specific results including how they intersect with other forms of maltreatments and other adverse experiences to produce health and other challenges in adults. Some of the key results discussed include:What was learned about childhood maltreatment, and its connection to health outcomes in adults, in this study of 8500 Australians How domestic violence is present in the 5 most common clusters of overlapping types of maltreatment How men were more likely to report smoking and cannabis use as result of childhood exposure to domestic violenceHow women were more likely to report self harm, suicide attempts and obesity as a result of childhood exposure of domestic violence How female and gender diverse children were more likely to experience childhood exposure to domestic violence Read about the study: https://www.acms.auRead more about resources and publications from the Institute of Child Protection Studies for adopting a public health approach to protecting children: https://www.acu.edu.au/icps/public-healthOther related Partnered with A Survivor episodes Season 5 Episode 5: A Trauma History is Not An Excuse for Acting AbusivelySeason 5 Episode 4: Unveiling The Impact Of Domestic Violence On Children: Beyond The Myth Of The Child WitnessSeason 4 Episode 10: Ensuring The Voice Of The Child Is Heard, And Child's Best Interests Are Considered In Domestic Abuse Cases Now available! Mapping the Perpetrator's Pattern: A Practitioner's Tool for Improving Assessment, Intervention, and Outcomes The web-based Perpetrator Pattern Mapping Tool is a virtual practice tool for improving assessment, intervention, and outcomes through a perpetrator pattern-based approach. The tool allows practitioners to apply the Model's critical concepts and principles to their current case load in realCheck out David Mandel's new book "Stop Blaming Mothers and Ignoring Fathers: How to transform the way we keep children safe from domestic violence."
In this episode of the Curious Realm, host Christopher Jordan ventures forth to the 2024 MUFON Symposium to we delve into the topics of UFOs and UFO/UAP Transparency as we talk to researchers, authors, and field investigators at the Conference. Our first guest is Marianne Robb a retired Arizona police officer and co-founder of UAP-PD, an organization dedicated to destigmatizing the topic of UFO/UAP in the law enforcement community, as well as helping train investigators in properly taking witness interviews and evidence collection. Next, we have the chance to sit down with Richard Beckwith is a member of the MUFON Board of Directors and has been with MUFON for more than 20 years, and State Director of MUFON Wyoming. He has been a practicing attorney for 30 years and presently serves as the City Attorney for the City of Rock Springs, Wyoming. We discuss the present legal hurdles in the road to disclosure, as well as the implications involved with changing the world paradigm with this information. Our next guest is Kathleen Marden, Founding member of the MUFON Experiencer Resource Team (ERT), abductee, and niece of Betty and Barney Hill. We talk about the necessity of reaching out to experiencers, contactees, and abductees to help them overcome the PTSD from their traumatic experiences, as well as the spiritual changes that seem to occur in abductees after their experiences. In this segment we are joined by Director of Southern California MUFON, and MUFON Experiencer Resource Team (ERT) member Earl Grey Anderson. We discuss the world of ET experiencers, the massive changes it has on their live and the importance of approaching every investigation into UFOs/UAPs with an open heart, an open mind, and a critical eye for detail. Up next, we have the pleasure of sitting down with Geraldine Stith, member of the family who witnessed the now famed case of the “Hopkinsville Goblins”/ We discuss how the incident on that fateful night affected her family for the rest of their lives, and how the town in which it happened is divided by the incident. Or next guest is Shanelle Schanz, granddaughter of Kenneth Arnold, the now famed pilot who witnessed a formation of silver craft flying like a “saucer skipping over water…” giving birth the turn-of-phrase “Flying Saucers”. We discuss how this event changed her grandfather's life, the impact of his sighting on the world, and her grandfather's legacy. Our next guest is Robert Spearing, MUFON's Director of International Investigations. We discuss his conference presentation on materials unknown that have been sent to and analyzed by MUFON labs…some with very strange properties. Our next guest is Dr Barabara Schuessler Sobhani, director of the Colorado Space Grant, and daughter of the founder of MUFON. We discuss the current state of space exploration and the technologies being developed. We also talk about the importance of an open mind in scientific exploration, the hurdles faced UFO/UAP investigations in scientific communities, as well as the new MUFON legacy fund, which bears her mothers name, and the importance of continuing the work of MUFON. Up next, we are joined by Dr Roger Stankovic, Neurologist, and nation director of MUFON Australia. We discuss his ground-breaking work in studying the connections between the neurologic brain injuries and symptomologies suffered by Havana Syndrome victims and their presence within experiencers of UFO contact and abduction. Next, we are joined by Jeremy Ray, Chief Investigator for MUFON Colorado. We discuss the many issues that5 come about during a MUFON investigation as well as the ongoing obfuscation of information regarding UFOs in the Government and the need for accountability in the world of the disclosure movement. Next, we are joined by Margie Kay, author, researcher, and co-founder of the UnX Network, a network dedicated to programs in the world of UFO/UAP, Paranormal, and Esoteric. We discuss the current climate of UFO conversation in the world, the ways in which larger conversations on the topic have been opened, as well as the interconnection of UFOs, the paranormal, and more. We have the pleasure to sit down with Joann Donaldson, scientist, and former member of the Apollo mission launch and recovery team. We discuss the massive undertaking needed to not only accomplish the Apollo missions, but the technology that had to be developed from the ground up, as well as the burning question on every conspiracists mind…did we go to the Moon?! Our final guest is author, artist, and researcher Jason Mclean. We discuss his experience at his first MUFON Symposium. We also talk about the need for citizen scientists and why data needs to be properly gathered at the moment of experience when in the field investigating UFOs/UAPs, the paranormal, and cryptozoology. Join the Curious realm as we provide on site coverage for the 2024 MUFON International Symposium! Curious Realm is proudly distributed by& Aftermath Media, KGRA, APRTV and the official Curious Realm ROKU App! Curious Realm has teamed up with True Hemp Science, Austin, TX based suppliers of high-quality full spectrum emulsified CBD products and more. Visit TrueHempScience.com TODAY and use code Curious7 to save 7% off your order of $50 or more and get a free 50mg CBD edible! Website live streams powered by Web Work Wireless. For the best in home and business WiFi solutions visit WebWorksWireless.com. Intro music “A Curious Realm” provided by No Disassemble find more great music and content at: NoDisassemble.com. #CuriousRealm #truehempscience #webworkswireless Curious Realm: Where theBecome a supporter of this podcast: https://www.spreaker.com/podcast/curious-realm--5254986/support.
In this episode of the Curious Realm, host Christopher Jordan ventures forth to the 2024 MUFON Symposium to we delve into the topics of UFOs and UFO/UAP Transparency as we talk to researchers, authors, and field investigators at the Conference. Our first guest is Marianne Robb a retired Arizona police officer and co-founder of UAP-PD, an organization dedicated to destigmatizing the topic of UFO/UAP in the law enforcement community, as well as helping train investigators in properly taking witness interviews and evidence collection. Next, we have the chance to sit down with Richard Beckwith is a member of the MUFON Board of Directors and has been with MUFON for more than 20 years, and State Director of MUFON Wyoming. He has been a practicing attorney for 30 years and presently serves as the City Attorney for the City of Rock Springs, Wyoming. We discuss the present legal hurdles in the road to disclosure, as well as the implications involved with changing the world paradigm with this information. Our next guest is Kathleen Marden, Founding member of the MUFON Experiencer Resource Team (ERT), abductee, and niece of Betty and Barney Hill. We talk about the necessity of reaching out to experiencers, contactees, and abductees to help them overcome the PTSD from their traumatic experiences, as well as the spiritual changes that seem to occur in abductees after their experiences. In this segment we are joined by Director of Southern California MUFON, and MUFON Experiencer Resource Team (ERT) member Earl Grey Anderson. We discuss the world of ET experiencers, the massive changes it has on their live and the importance of approaching every investigation into UFOs/UAPs with an open heart, an open mind, and a critical eye for detail. Up next, we have the pleasure of sitting down with Geraldine Stith, member of the family who witnessed the now famed case of the “Hopkinsville Goblins”/ We discuss how the incident on that fateful night affected her family for the rest of their lives, and how the town in which it happened is divided by the incident. Or next guest is Shanelle Schanz, granddaughter of Kenneth Arnold, the now famed pilot who witnessed a formation of silver craft flying like a “saucer skipping over water…” giving birth the turn-of-phrase “Flying Saucers”. We discuss how this event changed her grandfather's life, the impact of his sighting on the world, and her grandfather's legacy. Our next guest is Robert Spearing, MUFON's Director of International Investigations. We discuss his conference presentation on materials unknown that have been sent to and analyzed by MUFON labs…some with very strange properties. Our next guest is Dr Barabara Schuessler Sobhani, director of the Colorado Space Grant, and daughter of the founder of MUFON. We discuss the current state of space exploration and the technologies being developed. We also talk about the importance of an open mind in scientific exploration, the hurdles faced UFO/UAP investigations in scientific communities, as well as the new MUFON legacy fund, which bears her mothers name, and the importance of continuing the work of MUFON. Up next, we are joined by Dr Roger Stankovic, Neurologist, and nation director of MUFON Australia. We discuss his ground-breaking work in studying the connections between the neurologic brain injuries and symptomologies suffered by Havana Syndrome victims and their presence within experiencers of UFO contact and abduction. Next, we are joined by Jeremy Ray, Chief Investigator for MUFON Colorado. We discuss the many issues that5 come about during a MUFON investigation as well as the ongoing obfuscation of information regarding UFOs in the Government and the need for accountability in the world of the disclosure movement. Next, we are joined by Margie Kay, author, researcher, and co-founder of the UnX Network, a network dedicated to programs in the world of UFO/UAP, Paranormal, and Esoteric. We discuss the current climate of UFO conversation in the world, the ways in which larger conversations on the topic have been opened, as well as the interconnection of UFOs, the paranormal, and more. We have the pleasure to sit down with Joann Donaldson, scientist, and former member of the Apollo mission launch and recovery team. We discuss the massive undertaking needed to not only accomplish the Apollo missions, but the technology that had to be developed from the ground up, as well as the burning question on every conspiracists mind…did we go to the Moon?! Our final guest is author, artist, and researcher Jason Mclean. We discuss his experience at his first MUFON Symposium. We also talk about the need for citizen scientists and why data needs to be properly gathered at the moment of experience when in the field investigating UFOs/UAPs, the paranormal, and cryptozoology. Join the Curious realm as we provide on site coverage for the 2024 MUFON International Symposium! Curious Realm is proudly distributed by& Aftermath Media, KGRA, APRTV and the official Curious Realm ROKU App! Curious Realm has teamed up with True Hemp Science, Austin, TX based suppliers of high-quality full spectrum emulsified CBD products and more. Visit TrueHempScience.com TODAY and use code Curious7 to save 7% off your order of $50 or more and get a free 50mg CBD edible! Website live streams powered by Web Work Wireless. For the best in home and business WiFi solutions visit WebWorksWireless.com. Intro music “A Curious Realm” provided by No Disassemble find more great music and content at: NoDisassemble.com. #CuriousRealm #truehempscience #webworkswireless Curious Realm: Where theBecome a supporter of this podcast: https://www.spreaker.com/podcast/curious-realm--5254986/support.
Anthony Amore, Director of Security and Chief Investigator at the Isabella Stewart Gardner Museum in Boston discusses leading up, across, and beyond to create a culture of security.
What You Need to Know is that the narrative machine is real and active. Big tech, big media, big government, and big business creates narratives to tell the American people what they want them to think. The Russia hoax is an excellent example of the narrative machine in action. The Russia hoax lie was that Donald Trump was a Russian puppet, and all the levers of the narrative machine worked in tandem to push this story. They did the same in the cover up of the Hunter Biden laptop story, and they did the same with the January 6 narrative. Once you see the narrative machine, you can recognize it in everything that they do. Scott Walter, President at the Capital Research Center and author of ARABELLA: The Dark Money Network of Leftist Billionaires Secretly Transforming America, joins Ed to discuss his new book. Scott tells all about Arabella Advisors and how they funnel billions of dollars into our elections. They discuss how Scott discovered Arabella and realized the true extent of the influence by this beltway bandit. John Zadrozny, Chief Investigator at America First Legal, joins Ed to talk about the anniversary of America First Legal and the growth they have experienced. Zadrozny and Ed talk about the chronic legal inaction in the conservative movement, and how his organization seeks to fight the fights that must be fought. Zadrozny details the importance of the electoral college and its proper function in our American system. Wrap Up: We the People need robust and well-rounded sources if we're going to successfully “distrust and verify” then talk to our friends and family about it. Take a look at the Phyllis Schlafly network of the Phyllis Schlafly Report and column, the Pro America Report, Unauthorized Caucus, and the Education Reporter for some great sources that take you across the issues and deep into them as well.See omnystudio.com/listener for privacy information.
What You Need to Know is the Deep State is real and we have the evidence! Don't let the left back us into a corner when great folks like Scott Walter are hot on the trail of their evidence. If you know people who just haven't quite made that leap from their initial conservative leanings, it's time to get them plugged into stories like Arabella Advisors and the work Scott Walter and Capital Research Center are doing. Scott Walter, President at the Capital Research Center and author of ARABELLA: The Dark Money Network of Leftist Billionaires Secretly Transforming America, joins Ed to discuss his new book. Scott tells all about Arabella Advisors and how they funnel billions of dollars into our elections. They discuss how Scott discovered Arabella and realized the true extent of the influence by this beltway bandit. John Zadrozny, Chief Investigator at America First Legal, joins Ed to talk about the anniversary of America First Legal and the growth they have experienced. Zadrozny and Ed talk about the chronic legal inaction in the conservative movement, and how his organization seeks to fight the fights that must be fought. Zadrozny details the importance of the electoral college and its proper function in our American system. Wrap Up: Hypocrisy at the highest level! The DOJ is risking contempt of Congress to shield Joe Biden's audio recorded interviews with Special Counsel Hur from being given to the public. Talk about a double standard.See omnystudio.com/listener for privacy information.
0:00:00 Introduction Richard Saunders 0:04:36 Kenny Biddle Tiks on Tiktok It's hard to believe, but much of what you see on Tiktok may not be all it seems! Chief Investigator for the Committee for Skeptical Inquiry, Kenny Biddle, hunts for claims of the paranormal on Tiktok. Can he explain the unexplainable? https://www.tiktok.com/@kennybiddle42 0:20:56 Australian Skeptics Newsletter What skeptical news has caught the eye of Tim Mendham this week? Read by Adrienne Hill. http://www.skeptics.com.au 0:32:20 A Dive into a Trove A wander through the decades of digitised Australian newspapers on a search for references to yet more UFOs. 2014.01.27 - Woman's Day 2010.11.29 - New Idea http://www.trove.nla.gov.au Also Dick Smith's Helicopter Adventure - Parkinson 1982 https://youtu.be/TM_0q3m5i40 We Can Reason - Calgary Canada https://wecanreason.com
Online safety for children is a huge issue in our digital society and here at Alcohol Action Ireland we want to shine a light on how damaging digital advertising of harmful commodities, such as alcohol, can be. Currently in Ireland, through a new body called Coimisiún na Meán, we are developing new online safety rules for video sharing platform services, such as Facebook, Instagram, YouTube, Tik Tok and others. Today, we hear how we should protect children and their rights in this digital era. Our expert guests are human rights lawyer and Online Safety Coordinator for the Children's Rights Alliance, Noeline Blackwell, and director of the Center for Digital cultures and Societies at the University of Queensland, Associate Professor in the School of Communication and arts, Nicholas Carah. THINGS WE SPOKE ABOUT●How we can protect children from harmful advertising ●Dark advertising of alcohol that targets children ●The most important things for regulators to consider ●Why we need to listen to the voices of young people ●Taking pressure from parents and placing it on politcians GUEST DETAILSNoeline Blackwell is a human rights lawyer who joined the Children's Rights Alliance in November 2023 as Online Safety Co-ordinator. Prior to that, Noeline was CEO of Dublin Rape Crisis Centre for almost 8 years and was previously Director of FLAC, the Free Legal Advice Centres. Noeline also spent a number of years in general practice, with a particular focus in immigration, refugee and family law. She has been a member of a number of statutory and NGO boards. She currently chairs the Independent Patient Safety Council and the Child Law Project. She was appointed as a member of the Irish Human Rights and Equality Commission in 2023.https://ie.linkedin.com/in/noelineblackwell Nicholas Carah is Director of Digital Cultures & Societies in the Faculty of Humanities, Arts and Social Sciences and Associate Professor in the School of Communication and Arts. He is an Associate Investigator in the ARC Centre of Excellence for Automated Decision-Making and Society, and a Chief Investigator on ARC Discovery and Linkage projects. In 2023 they are Deputy Associate Dean (Research) in the Faculty of Humanities, Arts and Social Sciences. Nicholas' research examines the algorithmic and participatory advertising model of digital media platforms, with a sustained focus on digital alcohol marketing. He is the author of Media and Society: Power, Platforms & Participation (2021), Brand Machines, Sensory Media and Calculative Culture (2016), Media and Society: production, content and participation (2015), Pop Brands: branding, popular music and young people (2010). And, co-editor of Digital Intimate Publics and Social Media (2018) and Conflict in My Outlook (2022). Nicholas has also been involved in research projects on alcohol-related harms and nightlife culture and the use of digital media in fostering cultural change in drinking culture. Nicholas is a Director and Deputy Chair of the Foundation for Alcohol Research and Education.https://nicholascarah.com/nicholascarah MORE INFORMATIONRead our submission regarding Ireland's online safety code.https://alcoholireland.ie/our-work/policy/alcohol-marketing-protecting-children/ If you are looking for support visit https://www.hse.ie/eng/services/list/5/addiction/drugshivhelpline/ To find out more about Alcohol Action Ireland visit alcoholireland.ieKEYWORDS#children #regulation #advertising #alcohol #online Hosted on Acast. See acast.com/privacy for more information.
In this episode, Pip and Rich discuss the FRAIL-AF study: Joosten et al. Safety of Switching From a Vitamin K Antagonist to a Non–Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients With Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial. Circulation. 2024;149:279–289. This trial randomised the switching of elderly frail patients who were established on a vitamin K antagonist to either remain on this treatment or switch to a direct oral anticoagulant. They found increased rates of bleeding in the switch arm. However, there is a lot of detail that is not in the abstract! Pip and Rich take a deep dive into the manuscript, discuss their thoughts with Chief Investigator, Geert Jan Geersing on the trial, and put the findings into context with consultant haematologist David Sutton. To read more about this trial check out Rich's blog on it: https://classicalcompass.substack.com/p/frail-af Links FRAIL-AF: https://www.ahajournals.org/doi/epdf/10.1161/CIRCULATIONAHA.123.066485
Today we welcome special guest MUFON Chief Investigator for the State of Nebraska Tamara Stier. Tamara has been with MUFON for the past 4 years working as a Field Investigator and Now as The Chief Investigator of her State. We will be discussing some of the TOP cases she has worked on including one that is currently in progress that is considered a high level case. Tamara is also an investigator for the "Heartland Paranormal Research Group" so we will discuss how she got involved with them and her work there. We have some really cool information to go over today, So Strap On Those Seat Belts, were going for a Ride! TAMARA'S BIO: Tamara Stier is the Chief Investigator for Nebraska MUFON. She has been a MUFON investigator for over four years and has worked on a variety of MUFON cases from unusual lights in the sky to witnesses observing full space crafts. She is currently following up on case that has a high level of sighting and unusual events. Tamara has worked in the pharmaceutical clinical research field for over 27 years. Tamara's interest in the unusual started as a paranormal investigator and is part of Heartland Paranormal Research Group. She is a reiki master and an experienced dowser. She has conducted a variety of dowsing classes and lectured at paranormal summits. Tamara is also a paranormal event planner and coordinator. She specializes in website design, social media marketing, vendor management and event logistics. SPONSORED BY: 2024 "CURIOSITIES FESTIVAL" On May 4th, Tickets ONLY $5 per Person for a FULL Day of Events More Info on Our Webite UFOEncountersWorldWide.wordpress.com - DONATE/SPONSOR THE SHOW AT - https://paypal.me/JessePmufonFI - IT WILL HELP KEEP THE SHOW GOING, PLUS YOU GET A "SHOUT OUT" ON THE SHOW AND A PLACE ON THE WEBSITE! CONTACT ME: TWITTER - @AATPEAK WEBSITE - UFOENCOUNTERSWORLDWIDE.WORDPRESS.COM EMAIL - UFOENCOUNTERSWORLDWIDE@GMAIL.COM --- Support this podcast: https://podcasters.spotify.com/pod/show/ufoencountersworldwide/support
Treveon Isaiah Taylor, Jr., is to be the first child of Jessica Ross and Treveon Isaiah Taylor, Sr. In the early morning of July 9, Jessica Ross's water broke and she went into labor at 37 weeks gestation. At 8:40 pm, after over 10 hours of labor, she was fully dilated and her doctors told her to start pushing. It was at this point during delivery that Treveon Taylor Jr.'s shoulders got stuck. Jessica Ross and Treveon Taylor Sr. asked the doctor to perform a c-section. Dr. Tracey St. Julian reportedly continues to try and force a vaginal birth and Jessica Ross continues to push. At 9:26 pm the fetal monitor showed an abnormal fetal heartbeat and the heart rate continued to decrease for the next hour and 10 minutes. By 10:36, there is no sign of a fetal heartbeat on the monitoring strips and Dr. St. Julian preps to perform an emergency c-section. At 12:11 am the baby's body and legs are delivered by c-section, but his head is delivered vaginally. The baby is decapitated during the birth process. Joining Nancy Grace Today: Dale Carson – Criminal Defense Attorney (Jacksonville), Former FBI Agent, Former Police Officer, Author: “Arrest-Proof Yourself;” X: @DaleCarsonLaw Dr. Heidi Green - Clinical Psychologist, Trauma Specialist, and Author: ‘The Path to Self-Love and World Domination,www.drheidigreen.com, IG: @drheidigreen Barry Hutchison Sr. – Former Law Enforcement, Owner & Chief Investigator for Barry & Associates Investigative Services LLC Joe Scott Morgan – Professor of Forensics: Jacksonville State University, Author, “Blood Beneath My Feet,” and Host: “Body Bags with Joseph Scott Morgan;” Twitter/X: @JoScottForensic Dr. Maneesha Pandey – Chief Forensic Pathologist for Forensic Pathologists LLC in Ohio, Board-Certified Forensic Pathologist Ashli Lincoln - Investigative Reporter, WSBTV Channel 2 News in Atlanta; IG: @ Ashlijoi, FB & X: @AshliLincoln Nicole Partin – CrimeOnline.com Investigative Reporter; X: @nicolepartin See omnystudio.com/listener for privacy information.
What You Need to Know is Ronna McDaniel has announced that she will not be continuing as chairwoman of the RNC. Reince Priebus, the former RNC chair, worked very hard to get Trump elected, but he was over his head as chief of staff for Donald Trump. Before he left, though, he did what he could to get McDaniel into the chair position. She should have stepped down after the 2020 mess, but she is doing it now. Now, Trump has the opportunity to back a new candidate for the RNC chair. This is a very important position, especially during the election cycle, for fundraising and getting out the vote. The question going forward is: will grassroots Republicans be able to get high positions in the RNC without big money? John Zadrozny, Chief Investigator at America First Legal, joins Ed to talk about the continued lawfare against Donald Trump. John emphasizes how the attack on Trump by New York's justice system is leading New York City to neglect prosecuting actual criminals in the city. This will not turn out well for Alvin Bragg, Zadrozny explains. Sabin Howard is a master sculptor and creator of the new World War I national memorial. Sabin explains why no World War I monument had been created before, as well as how Sabin received the honor of being the sculptor to create the memorial. Learn more at Sabinhoward.com! Wrap Up: We the People need robust and well-rounded sources if we're going to successfully “distrust and verify” then talk to our friends and family about it. Take a look at the Phyllis Schlafly network of the Phyllis Schlafly Report and column, the Pro America Report, Unauthorized Caucus, and the Education Reporter for some great sources that take you across the issues and deep into them as well.See omnystudio.com/listener for privacy information.
Early toxicology results for three friends found dead outside a Chiefs watch party, reportedly show cocaine and fentanyl in their systems. The families of David Harrington, Clayton McGeeney and Ricky Johnson confirmed the police have the initial toxicology reports. According to a family member, who wants to remain anonymous, the level of drugs in their system is high, three times the amount of a lethal fentanyl dosage. The families of Davide Harrington, Clayton McGeeney, and Ricky Johnson confirmed to WDAF the police have the reports and have shared some of the information with the families. Police say the case remains an ongoing death investigation. Joining Nancy Grace Today: Dale Carson - High Profile Criminal Defense Attorney (Jacksonville), Former FBI Agent, Former Police Officer (Miami-Dade County), Author: "Arrest-Proof Yourself”, DaleCarsonLaw.com, Twitter: @DaleCarsonLaw Caryn L. Stark- Psychologist, renowned TV and Radio trauma expert and consultant, www.carynstark.com, Instagram: carynpsych, FB: Caryn Stark Private Practice Barry Hutchison Sr. - fmr. Law Enforcement, Owner & Chief Investigator for Barry & Associates Investigative Services LLC., www.barryinvestigationsllc.com Dr. William Morrone -Medical Examiner, Toxicologist, Pathologist, opioid treatment expert, Author: “American Narcan: Naloxone & Heroin-Fentanyl associated mortality” Grace Smith KCTV5 Reporter, www.kctv5.com/authors/Grace-Smith/, IG: @Gracesmithnews, X: @GraceKCTV5 See omnystudio.com/listener for privacy information.
My guest today is Dr Claire Park. Dr. Park is a Consultant in Pre-Hospital Emergency Medicine for London HEMS, and Anesthesia and Critical Care Medicine at Kings College Hospital in London. She is also an army consultant with over 20 years of deployed military experience. Claire is the Medical Adviser to the Specialist Firearms teams of the Metropolitan Police Service and has worked closely with all of the emergency services in London on developing the joint response to high threat incidents, in particular following the attacks of 2017. She is also the Chief Investigator on a UK nationally funded research grant looking at evidence for improving patient outcomes in the hot zone of major incidents. I am excited to have Claire on the show because she has a unique combination of real-world experience in combat theaters and practical experience and research in civilian tactical law enforcement. She has also been at the forefront of the UK's new approach to mass casualty events and the 10 second triage system. Contact Info Dr. Claire Park claire@etma.lifeX - @ClairePark01
Today we welcome special guest Larry Tyree who is a Certified MUFON Field Investigator in Illinois and a member of the COPA Team or Combined Photographic Analysis Team from both Missouri and Illinois MUFON Investigators. We will be discussing Larry's very own UFO sighting and his research into "Fast Movers". The topic of "Fast Movers" have become such a big part of UFO research that Larry was part of a team that wrote the book on them called "The Fast Movers: Evidence of High Speed UFO/UAP's" in which we will discuss the content expected in the book. Larry has also done research into whats called "Starburst Craft Experiences" something I have yet to hear about so this should be a refreshing conversation today. We will touch on some other aspects as well so lets not waste any more time, Strap On Those Seat Belts, were going for a Ride! - SPONSORED BY: Project BATTECH 404 - Investigating Electrical Malfunctions Associated with UFO Sightings/Encounters, You can help UFO Research by Reporting your EM UFO Encounter at -Battech404reseachmembers@gmail.com LARRY'S BIO: Larry Tyree is a Field Investigator with Illinois Chapter of MUFON. He is also part of a Combined Photographic Analysis team (COPA) from both Missouri and Illinois investigators. He enjoys assisting MUFON investigators by examining video evidence and providing an analysis of the video. Previously he was Chief Investigator with the Missouri Chapter of the Mutual UFO Network. Larry has made numerous video lecture presentations that exhibit images and data from cases that he has investigated. Larry has had a number of his investigated cases highlighted in the national publication “The MUFON Journal” over the last several years. One recent case was included in “UFO Cases of Interest, 2019 Edition”. His first book was co-written with Margie Kay and Bill Spicer and entitled “The Fast Movers”. Along with the same co-authors, a new book is being assembled and will be published hopefully sometime the Spring of 2024 entitled “Earth's Unseen Inhabitants”. FAST MOVER'S BOOK - https://www.amazon.com/Fast-Movers-Evidence-High-Speed-UFOs/dp/0998855863/ref=sr_1_1?keywords=The+Fast+Movers&qid=1704394557&sr=8-1 - SPONSORED BY: Project BATTECH 404 - Investigating Electrical Malfunctions Associated with UFO Sightings/Encounters, You can help UFO Research by Reporting your EM UFO Encounter at -Battech404reseachmembers@gmail.com - DONATE/SPONSOR THE SHOW AT - https://paypal.me/JessePmufonFI - IT WILL HELP KEEP THE SHOW GOING, PLUS YOU GET A "SHOUT OUT" ON THE SHOW AND A PLACE ON THE WEBSITE! CONTACT ME: TWITTER - @AATPEAK WEBSITE - UFOENCOUNTERSWORLDWIDE.WORDPRESS.COM EMAIL - UFOENCOUNTERSWORLDWIDE@GMAIL.COM --- Support this podcast: https://podcasters.spotify.com/pod/show/ufoencountersworldwide/support
What You Need to Know is that there was a hearing at the House Foreign Affairs committee, in which Chairman McCaul brought up the importance of the Monroe Doctrine and its bicentennial. I was on Bannon's War Room a couple of days ago discussing the continuing importance of the Monroe Doctrine. Many are coming to me and discussing the importance of the Monroe Doctrine. The American people are understanding how important the Monroe Doctrine is for America First. Keep celebrating, and keep spreading the message! Sgt. Betsy Brantner Smith (Ret.), spokeswoman for the National Police Association, joins Ed to discuss New York City's plans to cancel the next five Police Academy classes. As high crime rates continue and the migrant crisis worsens, this is certainly not the time for New York City to be cutting the budget on its police force. Sgt. Smith gives a detailed account of the state of policing in New York City. John Zadrozny, Chief Investigator at America First Legal, joins Ed to talk about the recent House hearing on the border crisis. The America First Legal team did a fantastic job of demonstrating to Congress what a safe and effective immigration system should look like. Ed and Zadrozny also discuss the dynamics of public hearings, and how this may be motivating Hunter Biden. Wrap Up: Joe Biden gets blasted on X for claiming it's business price gouging and not astronomical inflation that's hurting consumers' wallets.See omnystudio.com/listener for privacy information.
In this podcast episode, we welcome to the show Ryan Stacey. Ryan delves into his approach of using the ultraspectrum classification system to categorize and explore unexplained phenomena cases. He emphasizes focusing on the experiencer rather than the paranormal phenomena itself, believing that studying various experiencer cases leads to a deeper understanding of the interconnectedness of unexplained phenomena. Ryan Stacey is a certified Private Investigator and is the President and founder of The Experiencer Support Association (TESA). He is also the host of the Beyond the Thin Foil Hat Podcast and several other media programs. He previously worked with MUFON as the Director of Field Investigator Training and was the national Chief Investigator for MUFON in Canada. To learn more about Ryan Stacey, visit the Experience Support Association website at www.experiencersupport.org, and catch the Beyond the Tin Foil Hat podcast on YouTube: https://www.youtube.com/watch?v=ry2gVj69_GY&t=2s.You can find the host Jamie here:Bob Olson Best Psychic Directory:https://bestpsychicdirectory.com/california/Jamie-Lynn-l.htmlwww.electricspiritpodcast.com@electricspiritpodcasthttps://psychicjamie.com/@socalhealerElectric Spirit Podcast Merchandise:https://www.electricspiritpodcast.com/store Electric Spirit Podcast Facebook Group:https://www.facebook.com/groups/661261524931303/?ref=share_group_linkElectric Spirit Podcast YouTube channel:https://youtube.com/@electricspiritpodcastSUPPORT:https://www.buymeacoffee.com/jamielynn12Disclaimer:https://psychicjamie.com/jdisclaimerPlease note: The opinions stated by the guests are not always the opinions of Jamie Lynn's.This podcast is for educational purposes only. The host claims no responsibility to any person or entity for any liability, loss, or damage caused or alleged to be caused directly or indirectly as a result of the use, application, or interpretation of the information presented herein.Thank you for joining us for this new episode, commenting and sharing!https://www.buymeacoffee.com/jamielynn12#beyondthefinfoilhat; #experiencersupportassociation; #paranormal #ufos #extraterrestrials #Aliens #PsychicsSupport the show
0:00:00 Introduction Richard Saunders 0:03:32 You Can Count on Adrienne This week Adrienne interviews Susan Gerbic ftom Guerrilla Skeptics on Wikipedia. Susan, together with a host of other sceptics, as soon to head to Melbourne for the Australian Skeptics National Convention. Find out what Susan will be talking about in Melbourne and how you can meet this inspirational, skeptical activist. http://www.skepticon.org.au 0:10:24 The Book of Tim. With Tim Mendham What Goes Around By Tim Mendham Geese, Golddiggers and San Francisco. A reading from The Skeptic, Vol. 34 No. 3 http://www.skeptics.com.au 0:18:32 Testing a Paranormal Claim We join the Center for Inquiry Investigations Group as they test a claim of being sble to move clouds with paranormal powers. Incudes commentary by Kenny Biddle, Chief Investigator for the CENTER FOR INQUIRY. https://cfiig.org 0:27:10 A Dive into a Trove A wander through the decades of digitised Australian newspapers on a search for references to "Telepathic Twins". http://www.trove.nla.gov.au Also 10 Years Ago The Skeptic Zone #264 - 9.November.2013 Maynard's Spooky Action... Maynard interviews Dr Rob Morrison about 'The Curiosity Show', an Australian educational children's television show produced from 1972 to 1990. Find out how the show started, some of the adventures along the way and how you and your children can now enjoy this landmark of Australian TV - A Week in Science - Don't get fooled at the Track. From the Scamwatch web site, advice about not getting taken for a ride at the racing track - Sydney Skeptics in the Pub. The question this week... If you could go to Mars but not come back.. would you? https://skepticzone.libsyn.com/the-skeptic-zone-264-9-nov-2013
Kenny Biddle is an actual ghost hunter. He's also Chief Investigator at The Committee for Skeptical Inquiry. He's got some stories. VIDEO of this interview: https://youtu.be/-x8OcpN4dUIThis show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/3270347/advertisement
This week on the podcast Mikki chats to Prof David Dunstan about the dangers of sedentary behaviour and prolonged sitting. They discuss what sedentary behaviour actually is and how this differs from inactivity. They discuss the physiological changes that occur when we are sedentary and how it impacts our cardiovascular and respiratory health, how it impacts on fat deposition and at a population level, what is the % of people who could be considered sedentary. They discuss the physical activity guidelines and if these are enough to offset the risks associated with being sedentary, and also discuss recent research investigating the relationship between Quality of Life markers, psychological health and sedentary behaviour during Covid. Professor David Dunstan is the head of the Baker-Deakin Department of Lifestyle and Diabetes within the Institute for Physical Activity and Nutrition. He also holds the positions of Deputy Director and Laboratory Head (Physical Activity) at the Baker Heart and Diabetes Institute. His research focuses on understanding the adverse health consequences of too much sitting and the potential health benefits resulting from frequently breaking up sitting time with active countermeasures. In particular, he has developed effective strategies to reduce and break up sitting time in adults with or at risk of developing chronic diseases and to support office workers to reduce sedentary behaviour in workplace settings. He is also interested in how best to implement efficacious ‘sit less and move more' interventions at scale within healthcare settings for those living with or at risk of chronic disease. He was supported by external research fellowships for 16 years and has been a Chief Investigator on 18 nationally-funded studies worth approximately $17 million and 11 international studies from the UK, USA, Sweden and Finland worth more than US$20 million. Professor Dunstan was a Clarivate Highly Cited Cited Researcher in 2018, 2019, 2020 and 2021, placing him in the top 1% most cited for his subject field and year of publication. He has published over 340 peer-review papers and 5 book chapters and has a Scopus H-index of 79. Other highlights include: being an invited author on the 2016 Physical Activity/Exercise and Diabetes Position Statement of the American Diabetes Association; invited presentations at scientific meetings for the American Diabetes Association and European Society for the Study of Diabetes; and current Vice-President of the Asia-Pacific Society for Physical Activity (ASPA).Prof Dunstan: https://www.baker.edu.au/research/staff/david-dunstanReearch: https://www.researchgate.net/profile/D-Dunstan Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenSave 20% on all NuZest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk ooff your first order
CTL Script/ Top Stories of September 30th Publish Date: Sept 29th Henssler :15 From the Ingles Studio Welcome to the Award Winning Cherokee Tribune Ledger Podcast Today is Saturday, September 30th, and happy 51st birthday to NFL running back Jamal Anderson. ***Jamal Anderson PxP*** I'm Keith Ippolito and here are the stories Cherokee is talking about, presented by Credit Union of Georgia Cherokee district attorney's office chief investigator retires Food Network's Chef Brian Duffy coming to Cherokee County charity BBQ event Woodstock man celebrates 102nd birthday We'll have all this and more coming up on the Cherokee Tribune-Ledger Podcast, and if you're looking for Community news, we encourage you to listen and subscribe! Commercial: CU of GA - ESOG STORY 1: Cherokee district attorney's office chief investigator retires Cherokee County District Attorney's Office Chief Investigator Dwight Kelley is retiring after 36 years of service. A retirement reception was held in his honor. District Attorney Susan Treadaway praised Kelley's dedication and the impact he's had on the office. Kelley, who served in various law enforcement roles, has been the chief investigator for 26 years and leaves behind a skilled team. Brandon Owens will become the new chief investigator, and William Hegwood will be the assistant chief investigator. Both have extensive law enforcement backgrounds and training. Kelley expressed confidence in their abilities to continue the office's work......……Read more on this story at tribuneledgernews.com STORY 2: Food Network's Chef Brian Duffy coming to Cherokee County charity BBQ event Chef Brian Duffy, known from Food Network shows like BBQ Brawl, is set to visit Red White and Blue BBQ in Canton in late October. The event, taking place on October 27-28 at the Canton American Legion, will feature him as a food critic and judge for a mystery food cook-off on the 27th, where amateurs and professionals compete. On the 28th, he'll judge the main barbecue event and host a public cooking demonstration. The event aims to showcase Canton's BBQ scene and local foods, with all proceeds supporting veteran mental health awareness and suicide prevention programs in Cherokee and Pickens counties. STORY 3: Woodstock man celebrates 102nd birthday Roger Antonucci, a Woodstock man, celebrated his 102nd birthday with family and friends at Oaks at Towne Lake. He's been a resident there for nearly three years. Known for his positive attitude, he worked as a tailor for over 30 years and maintained a daily walking routine for 40 years. Described as a "ladies' man" and "calm, cool, and collected," he credits his long life to a secret he won't reveal. Members of the Cherokee Sheriff's Office also joined the celebration, honoring Antonucci on his special day. We have opportunities for sponsors to get great engagement on these shows. Call 770.874.3200 for more info. Back in a moment Break: ELON - Drake - Dayco STORY 4: Holly Springs City Council approves rezoning for 20 townhomes The Holly Springs City Council has approved a request to rezone nearly two acres for the construction of a 20-unit townhome community along Edmondson Lane. The rezoning changes the designation from general commercial to traditional neighborhood development with a density of 10.05 units per acre. The proposed townhomes are expected to be priced at $400,000 or less. Additionally, the council voted to approve an intergovernmental agreement with Cherokee County, Woodstock, and the Cherokee Office of Economic Development for a transportation plan for the I-575 and Sixes Road area. Other approvals include declarations for covenants, conditions, restrictions, and easements for various residential projects and contracts for park improvements. Story 5: Cherokee Fire promotes 10 firefighters On September 26, Cherokee County Fire and Emergency Services held a promotion ceremony at the Cherokee County Fire Training Complex in Holly Springs. Ten firefighters were promoted, including eight Fire Apparatus Operators who were promoted to the rank of sergeant, one sergeant who was promoted to lieutenant, and Battalion Chief Daniel Carder, who was promoted to the rank of division chief. The event was attended by family, friends, and colleagues to celebrate the accomplishments of the promoted firefighters. Commercial: Heller Law – CHEROKEE CHAMBER – POWERS Story 7: Cherokee County principal earns leadership award Mark Smith, Principal of ACTIVE Academies, received the Cristal Stancil Leadership Award from the Cherokee County Chamber of Commerce. The award recognizes exceptional leadership among participants in the Leadership Cherokee program, which helps develop community leaders through a nine-month program. Smith, a 20-year educator, currently leads the ACTIVE Academies campus in Canton and has a history of serving in various educational roles within the Cherokee County School District. The award was presented at the program's graduation ceremony, where Smith also delivered the class address. The honor reflects his dedication to education and servant leadership. STORY 8: Woodstock leaders OK annexation and rezoning for 88-unit neighborhood The Woodstock City Council has approved the annexation and rezoning of 201 Brownlee Road for an 88-unit single-family townhome community. The property was rezoned to downtown-medium density residential, and a conditional use permit was granted. The project includes the extension of Brownlee Road. The council also approved a $20.6 million amendment to the contract with Winter Construction for phase two of the City Center Parking Deck project. They held three public hearings, including one about electric vehicle charging stations, which was tabled for further discussion. Additionally, they approved ordinances related to sign waivers and pet shops and accepted a $1.5 million loan for a transportation project. We'll have closing comments after this. Henssler 60 – INGLES 1 – Cumming Fair Thanks again for listening to today's Cherokee Tribune Ledger podcast. . If you enjoy these shows, we encourage you to check out our other offerings, like the Marietta Daily Journal Podcast, the Gwinnett Daily Post, the Community Podcast for Rockdale Newton and Morgan Counties, or the Paulding County News Podcast. Get more on these stories and other great content at tribune ledger news.com. Giving you important information about our community and telling great stories are what we do. Did you know over 50% of Americans listen to podcasts weekly? Make sure you join us for our next episode and be sure to share this podcast on social media with your friends and family. Add us to your Alexa Flash Briefing or your Google Home Briefing and be sure to like, follow, and subscribe wherever you get your podcasts. www.henssler.com www.ingles-markets.com www.esogrepair.com www.daycosystems.com www.powerselectricga.com www.elonsalon.com www.jeffhellerlaw.com www.drakerealty.com www.cherokeechamber.com Cumming FairSee omnystudio.com/listener for privacy information.
This time, GCP does a throwback episode of show 152 with Dan Nims, the chief investigator for the Washington chapter of MUFON. Dan is retired from the US Air Force (thank you for your service) where he started his career as a fighter pilot and test pilot, followed by advancing to Director of Test for the F-22 program and finally Director of Test Resources. He spent his initial retirement years as a small businessman in Walla Walla and is now re-retired. He has been a member of MUFON since 2017 and Chief Investigator since 2018. He handles on average 200 reported UFO cases per year. MUFON is an all-volunteer, non-profit 501(c)3 charitable corporation and the world's oldest and largest civilian UFO investigation & research organization. Their goal is to be the inquisitive minds' refuge seeking answers to that most ancient question, "Are we alone in the universe?" The Washington Chapter hosts a monthly lecture series on Zoom where anyone can ask questions and hear how MUFON of Washington State handles UFO cases. 00:24 - Justin reflects on the recording of this best of, talks about GCP ramping up this coming fall, and Jeff talks about getting out of the city to camp out. Justin talks about his trip to Ocean Shores, getting sprinkled on while there, and gives props to Brogan and his van. He gives a shout-out to Ocean Pores and talks about watching live music at Galway Bay Irish Pub. The guys give love to Porch Fest and jump into the replay. Special Guest: Dan Nims.
This episode we speak with Dr Brendan Keogh, discussing his new book The Videogame Industry Does Not Exist: Why We Should Think Beyond Commercial Game Production (https://mitpress.mit.edu/9780262545402/the-videogame-industry-does-not-exist/). It is the final part of a special 6-episode Season of Keywords in Play, exploring intersections and exchanges between Chinese and Australian game studies scholarship. This project has been assisted by the Australian Government through the Australia Council, its arts funding and advisory body. Dr Brendan Keogh (he/him) is a senior lecturer in the School of Communication and a Chief Investigator of the Digital Media Research Centre, Queensland University of Technology. He is the co-author of The Unity Game Engine and The Circuits of Cultural Software (Palgrave Macmillan, 2019; with Benjamin Nicoll), and is the author of The Videogame Industry Does Not Exist (MIT Press, 2023), A Play of Bodies: How We Perceive Videogames (MIT Press, 2018), and Killing is Harmless: A Critical Reading of Spec Ops The Line (Stolen Projects, 2012). He has written extensively about the cultures and development practices of videogames in journals such as Games and Culture, Creative Industries, and Covergence, and for outlets such as Overland, The Conversation, Polygon, Edge, and Vice. You can check out more of Brendan's work and games on his website: https://brkeogh.com/, and follow him on Twitter: https://twitter.com/brkeogh. The podcast series is part of the Engaging Influencers initiative. This initiative is curated by the Australia Council for the Arts and funded by the National Foundation for Australia-China Relations. As a joint venture, “Keywords in Play” expands Critical Distance's commitment to innovative writing and research about games while using a conversational style to bring new and diverse scholarship to a wider audience. Our goal is to highlight the work of graduate students, early career researchers and scholars from under-represented groups, backgrounds and regions. The primary inspiration comes from sociologist and critic Raymond Williams. In the Preface to his book Keywords: a vocabulary of culture and society, Williams envisaged not a static dictionary but an interactive document, encouraging readers to populate blank pages with their own keywords, notes and amendments. “Keywords in Play” follows Williams in affirming that “The significance is in the selection”, and works towards diversifying the critical terms with which we describe games and game culture.” Interviewer: Mahli-Ann Butt Production Team: Darshana Jayemanne, Emilie Reed, Zoyander Street Audio Direction and Engineering: Damian Stewart Double Bass: Aaron Stewart Special Thanks: Hugh Davies, Chloe Yan Li
Robert Riggs is a Peabody Award-winning investigative reporter and digital media entrepreneur. He has also received three coveted Alfred I. duPont Columbia University Journalism Awards for Investigative Reporting. The Peabody and duPont are respectively considered the broadcast TV equivalent of the Oscar and the Pulitzer.Texas A&M University named Robert an Outstanding Alumnus from the College of Architecture in recognition of his journalistic accomplishments. It is a distinction received by fewer than 1% of the College's graduates.Today, Riggs is the host and creator of the True Crime Reporter™ Podcast.During his journalism career, Riggs established a reputation for fairness, accuracy, credibility, and toughness in his reporting for the CBS Television Station Group - CBS 11 News, WFAA-TV (ABC) in Dallas-Fort Worth, Texas, and CBS Viacom reporting from the New York State Legislature. His investigative reports garnered a reputation for helping to send corrupt politicians and government officials to federal prison and were the catalyst for landmark changes in public policy.Riggs was an embedded reporter with the Army unit that led the invasion of Iraq in 2003 and he also covered Gulf War I. His assignments have included covering the White House, Congress, Pentagon, and State Department during the administrations of President Ronald Reagan and President George H.W. Bush.He appeared as a guest correspondent on ABC Nightline with Ted Koppel, CNN, and ESPN. CBS 60 Minutes and CBS News Online featured his investigative reports from Iraq. He reported from the “eye of the storm” of major breaking news stories including the mass murder at Luby's Cafeteria in Texas; the Branch Davidian siege in Waco; the Oklahoma City bombing; the standoff with the Republic of Texas separatists, and numerous natural disasters.Riggs' enterprise reporting primarily focused on the criminal justice system and national security with an emphasis on terrorism. In this connection, The University of Virginia Critical Incident Analysis Group and FBI selected Riggs in 2000 as an expert member of a multi-disciplinary panel that examined the architecture of terrorism and the symbolism of its targets. Meeting near the birthplace of Thomas Jefferson, the panel produced a landmark report entitled “Threats to Symbols of American Democracy” that prophetically identified vulnerabilities that would later tragically unfold during the 9-11 attacks.The Dallas Crime Commission awarded its first-ever Excellence in Crime Reporting Award to Riggs for his reporting on identity theft and Mexican Drug Cartels. The American Bar Association awarded him its Silver Gavel award for his investigative series Free To Kill which uncovered systemic corruption inside the Texas parole and prison systems.Prior to his journalism career, Riggs served as an investigator for the late Congressman Wright Patman of Texas who was Chairman of the House Banking Committee, Joint Economic Committee, and Joint Committee on Defense Production.As the Chief Investigator for the Joint Committee on Defense Production, Riggs spearheaded inquiries that touched on Watergate and Pentagon bribery scandals. He reported to the joint leadership of Representative Patman and Senator William Proxmire.In this role, Riggs held a Top Secret security clearance from the Department of Defense and received training from both the GAO and U.S. Army. The Committee's investigation of a defense contractor's bribery scheme contributed to the passage of the Foreign Corrupt Practices Act.Riggs currently belongs to the FBI's North Texas Chapter of InfraGard which was formed in response to the 9/11 terror attacks. He is also a longtime member of the Investigative Reporters & Editors (IRE).www.truecrimereporter.com