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TODAY ON THE ROBERT SCOTT BELL SHOW: LIVE from Natural Products Expo West, Mennonite Measles Medical Freedom, Western Diet & ADHD, Toxic Chemicals & Kids, Lakeland Bans Fluoride, Aseem Malhotra MAHA, $454M HHS Fraud, RFK Jr Vaccine Scrutiny, Phthalates in Essential Oils, Slow Cookers and Caster Oil and MORE! https://robertscottbell.com/live-from-natural-products-expo-west-mennonite-measles-medical-freedom-western-diet-adhd-toxic-chemicals-kids-lakeland-bans-fluoride-aseem-malhotra-maha-454m-hhs-fraud-rfk-jr-vaccine-scrut/
In an effort to bring on great guests to go beyond the narrow realm of fitness and nutrition, Dr Joe Zundell (PhD in Cancer Biology) joins me to talk about: -How strength training reduces cancer risk -How maintaining muscle and bone helps survive cancer treatment -Why the cancer cure suppression conspiracy theory is silly logic -What lifestyle behaviours contribute the greatest risk of developing cancer -The relationship between cancer and obesity -Why there's no one dietary ideology that helps to defeat cancer -and much more 00:15 Meet Dr. Joe Zundell 01:12 Strength Training and Cancer Risk 03:19 Understanding Cachexia 07:42 Cancer Treatment and Quality of Life 09:28 Cancer Complexity and Misconceptions 19:51 Environmental and Lifestyle Factors 26:00 Diet, Obesity, and Cancer Risk 32:03 The Impact of Western Diet on Liver Cancer 33:39 Dietary Advice for Cancer Patients 35:57 Understanding Autophagy and Its Role in Cancer 39:30 The Balance of Immune Response in Cancer Treatment 41:17 Debunking Myths About Cancer and Diet 48:51 The Role of Natural Remedies in Cancer Treatment 51:14 Conclusion and Final Thoughts I've been putting a lot of time and effort into making these new episodes valuable for you. You can help me get these great guests and their knowledge in front of more people by: -Subscribing and checking out more episodes -Sharing on your social media (please tag me - I promise I'll respond) -Sharing with the friend you think of who needs this episode Follow Andrew Coates: Instagram: @andrewcoatesfitness Join My Email List: www.andrewcoatesfitness.com
In this episode of The Moonshots Podcast, hosts Mike and Mark dive deep into Michael Pollan's groundbreaking book In Defense of Food, a manifesto challenging the modern diet culture and the industrial food system. With his iconic mantra, “Eat Food. Mostly Plants. Not Too Much,” Pollan explores how the Age of Nutritionism has hijacked our relationship with food and why it's crucial to return to real, whole foods.Through insightful clips from Pollan and engaging conversations, Mike and Mark uncover how processed foods and health claims have misled us. They also discuss actionable steps we can take to reclaim our health by eating mindfully.Together, they explore key themes such as: •
Dave MacLeod is one of the best all-around climbers in the world. He returns to the podcast to talk about his new book, Moving the Needle. We discuss the simple decisions that led to his success, getting the basics right, how to climb harder in your 40s, the value of daydreaming, writing books, how diet affects mood, Paul Saladino's meat and fruit approach, how to thrive on a keto diet, metabolic health, LCL cholesterol, seed oils, alcohol, the state of scientific research, and much more. Mad Rock:madrock.comUse code “NUGGET10” at checkout for 10% off your next order.AG1:drinkAG1.com/NUGGETUse this link to get a free year's supply of vitamin D + 5 travel packs.Arc'teryx:Women's climbing clothingMen's climbing clothingCheck out the Psiphon and Serratus Alpine Kits launching January 15th.PhysiVantage:physivantage.com (link includes 15% off coupon)Use code "NUGGET15" at checkout for 15% off your next order.The NUG:frictitiousclimbing.com/products/the-nugCheck out my new portable hangboard.Tindeq:tindeq.comUse code “nugget” for $10 off your order. Become a Patron:patreon.com/thenuggetclimbingWe are supported by these amazing BIG GIVERS:Michael Roy, Mark and Julie Calhoun, and Yinan LiuShow Notes: thenuggetclimbing.com/episodes/dave-macleod-returnsNuggets:(00:00:00) – Intro(00:02:34) – Themes for the today's podcast(00:04:59) – ‘Moving the Needle'(00:10:54) – How curiosity feeds consistency(00:17:44) – Simple decisions that move the needle(00:21:55) – Time x mileage x variety(00:34:09) – Balancing projecting & volume(00:41:08) – Tree crimping(00:43:50) – Almost daily training(00:49:08) – The basics(01:00:38) – When to end bouldering sessions(01:06:38) – Rolling with the punches(01:13:31) – Managing training load & staying in the game(01:24:43) – Finger training(01:30:09) – An unlikely breakthrough (FA of ‘Bultitude' V14)(01:37:09) – Finger strength PRs(01:43:42) – How to climb harder in your 40s(01:59:54) – Taking short breaks(02:02:56) – Daydreaming(02:05:30) – Making it hard to fail(02:13:27) – One thing at a time(02:17:19) – Writing books(02:25:25) – Factors that led to sending ‘Rhapsody' E11(02:32:16) – Books vs. podcasts(02:34:35) – Confidence & conflict(02:42:06) – Dave's experiment with a Western Diet(02:46:48) – How our diet can affect mood(02:52:26) – Paul Saladino, keto, fruit, & metabolic health(03:10:37) – Why Dave keeps coming back to keto(03:15:52) – How much protein Dave eats on keto(03:19:36) – Energy & weight management(03:26:40) – LDL Cholesterol(03:40:25) – Kitavan Islanders, heart disease, & lifestyle factors(03:46:51) – Seed oils & alcohol(03:49:25) – A need for unbiased scientific research(03:54:50) Where to buy Dave's book
Dr. Naidoo discusses the profound effects of the Western diet on cognition and mental health, emphasizing the importance of gut health and dietary choices in managing anxiety and overall well-being. Full episode: https://pod.fo/e/17fe96 --- Support this podcast: https://podcasters.spotify.com/pod/show/mentalkingmindfulness/support
In this enlightening interview, cardiologist and plant-based advocate Dr. Columbus Batiste discusses the profound connection between stress, nutrition, and heart health. Dr. Batiste shares his journey from a "junk food-itarian" to a passionate proponent of whole-food, plant-based living and explores why building resiliency, not eliminating stress, is key to living a long, healthy life. Dr. Batiste explains why “moderation kills,” how the Western diet is our biggest enemy, and the importance of committing to better nutrition. He also shares powerful insights on how environmental factors shape eating habits, and why he believes health is a right everyone deserves. Tune in to learn actionable advice on stress management, plant-based nutrition, and living a purposeful life. Follow Dr. Batiste here - https://www.instagram.com/healthyheartdoc/ - 00:00:00 Introduction and Guest Background - 00:02:34 Transition to Plant-Based Lifestyle - 00:07:43 Stress and Nutrition Connection - 00:11:41 Building Resiliency - 00:15:48 Racial Dynamics and Nutrition - 00:20:32 Practical Nutrition Advice - 00:27:30 Moderation and Mindset - 00:29:48 The Journey to Health and Self-Improvement - 00:30:52 The Confusion Around Veganism and Health - 00:32:39 The Impact of the Western Diet on Global Health - 00:34:28 The Importance of Plant-Based Diet for Cardiac Health - 00:39:26 The Role of Fiber in Nutrition - 00:41:09 The Phenomenon of Ex-Vegans - 00:45:24 The Concept of Selfish - 00:49:17 The Role of Community and Intimacy in Health - 00:50:18 The Importance of Sleep and Rest - 00:51:30 The Joy of Life and Stress Management - 00:52:35 Vision for the Future of Health and Wellness
In this episode, we have the privilege of speaking with Professor Chris Gardner, a renowned nutrition scientist and researcher at Stanford University. With a distinguished career dedicated to exploring the impacts of diet on health, Chris brings unparalleled expertise to our discussion. Chris recently featured in the Netflix documentary "You Are What You Eat," which delves into the complex world of nutrition and aims to demystify common misconceptions. We dive deep into the documentary's messages, explore the current state of the Western diet, and discuss the influence of convenience foods on modern eating habits. From government roles to personal responsibility, we cover diverse dietary traditions, the science behind protein requirements, and the role of diet in disease prevention. We also touch on the significance of gut health, mental wellness, and practical solutions for improving nutrition. Join us for an enlightening conversation that challenges conventional wisdom and offers insights for a healthier future. This show wouldn't be possible without our amazing sponsor Huel. To support the show please check them out at huel.com/roadman
Eat Your Greens with Dr. Black | plant-based nutrition for the whole family
Text Dr. Black your questions or comments.In episode 11 of Eat Your Greens with Dr. Black, listeners head to college to learn about the microbiome and its vital role in maintaining overall health. Dr. Black is joined by Dr. Micaela Vargas from the Department of Biology at Texas State University, and they discuss the complex and fascinating aspects of the microorganisms that live in our bodies, particularly our gut. The extensive effects of a healthy microbiome are outlined, from helping to prevent serious diseases like heart disease and cancer, to aiding digestion, regulating blood sugar, and potentially slowing aging. Listen in as Dr. Black and Dr. Vargas explore the impact of lifestyle factors such as diet, sleep, and exercise on the gut microbiome. The episode concludes with practical tips on how to nurture and support a healthy microbiome.Recipe for Dr. Black's breakfast smoothieConnect with Dr. Vargas: https://www.linkedin.com/in/micaelavargasphd/ Links to research articles The Human Microbiome Project Reaches Conclusion The origins of gut microbiome research in Europe: From Escherich to Nissle Current understanding of the human microbiome Association between antibiotics and gut microbiome dysbiosis in children: systematic review and meta-analysis Specific gut microbiome signatures and the associated pro-inflamatory functions are linked to pediatric allergy and acquisition of immune tolerance Faecal microbiota transplantation halts progression of human new-onset type 1 diabetes in a randomised controlled trial Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota Gut Microbiota: An Important Link between Western Diet and Chronic Diseases Anticancer EffectsIf you enjoyed this episode, please take a moment to rate it, leave a review, and most importantly, share it with a friend! For my free guide to Living a Plant-Forward Life, visit the show website and subscribe! eatgreenswithdrblack.com For resources related to a plant-based diet or if you struggle to afford healthy food for your family, please go to eatgreenswithdrblack.com/resources.You can contact Dr. Black at dr.black@eatgreenswithdrblack.comI am happy to answer general questions related to the information presented on this podcast. Be advised that I will never offer specific medical advice via this website, even if your child is an established patient in my practice. If you have concerns about your child's health or growth, please contact their doctor.Thanks for listening and don't forget to Eat Your Greens!
This episode with Dr. Pedro Bastos is a broad exploration of the role of inflammation in health and disease. In popular media, inflammation is regularly referenced only as a process that impairs our health, but as you'll learn today, inflammation also plays an essential and beneficial role in context. There is good inflammation and bad inflammation, and it is important to understand the difference.Dr. Bastos is a dietitian and researcher affiliated with the European University of Madrid in Spain, and Lund University in Sweden. At Lund, he studied and collaborated with Staffan Lindeberg, the principal investigator of the famous Kitava Study. He lectures extensively on health related topics worldwide and has co-authored influential papers such as "The Western Diet and Lifestyle and Diseases of Civilization, and "Chronic Inflammation in the etiology of disease across the lifespan", which was the most cited recent article in the influential journal, Nature Medicine. He has presented at the Ancestral Health Symposium, most recently in 2022 on a recap of the Kitava study.In this conversation, Dr. Bastos discusses the definition and function of inflammation, as well as the distinction between acute and chronic inflammation. He explains the various biomarkers used to detect inflammation and highlights their limitations. The conversation also explores the relationship between inflammation and oxidative stress, as well as the evidence supporting a connection between chronic inflammation and a range of diseases, including metabolic syndrome and autoimmune disorders. Inflammation plays a key role in various health conditions, including cardiovascular disease, Type 2 diabetes, and cancer. Chronic inflammation can both cause and be a consequence of immune processes. The Kitava study, conducted on a traditional population in Papua New Guinea, revealed that their diet, while high in carbohydrates and saturated fat, is relatively unprocessed and has characteristics that low may contribute to their lower levels of inflammation and better health outcomes. Other lifestyle factors, such as physical activity, sun exposure, sleep patterns, stress and lower exposure to pollutants, may also play a role in reducing inflammation-induced disease. From this, Dr. Bastos discusses how our diets can be tailored to minimize inflammation, including the roles of specific nutrients. The conversation touches on some debates around inclusion or exclusion of fiber, whole grains, dairy and alcohol. Overall, the discussion emphasizes the complexity of inflammation and the need for personalized approaches to promote optimal health.Resources: * "Chronic Inflammation in the etiology of disease across the lifespan", Nature Medicine, 24, 1822-1832 (2019) : https://www.nature.com/articles/s41591-019-0675-0* "The western diet and lifestyle and diseases of civilization", Research Reports in Clinical Cardiology 201, 1:2, 15-35 (2011): https://www.dovepress.com/the-western-diet-and-lifestyle-and-diseases-of-civilization-peer-reviewed-fulltext-article-RRCC-MVP * "Revisiting the Kitava study", Ancestral Health Symposium (AH22): Here is a guide to topics discussed in this podcast episode:Time Topic00:00 Introduction and background01:33 Definition and functions of inflammation04:44 Acute vs. chronic systemic inflammation09:04 Triggers of acute vs. chronic inflammation12:25 Inflammation biomarkers - uses and limitations19:48 Inflammation and oxidative stress26:45 The role of Inflammation in chronic diseases27:17 Inflammation in metabolic syndrome, diabetes and cardiovascular disease29:38 Inflammation in autoimmune disorders31:56 Inflammation in cancers34:04 Inflammation and cellular aging36:58 The Kitava study: Health findings47:54 The Kitava study: Dietary macronutrients, micronutrients and specific foods53:07 Inflammation in Kitavans vs. Swedish controls57:42 The role of lifestyle factors: sleep, physical activity, stress, sun exposure, sleep1:02:30 Mechanisms of stress-Induced Inflammation1:05:32 Pedro's dietary and lifestyle recommendations to control chronic Inflammation1:07:52 The importance of phytochemicals1:13:11 The question of fiber1:16:52 Grains, dairy and alcohol1:25:44 Summary and conclusions Get full access to Ancestral Health Today Substack at ancestralhealth.substack.com/subscribe
Join us for a groundbreaking episode as we challenge conventional dietary wisdom with Registered Dietician Mike Sweeney, who is leading the charge against the status quo. In a world saturated with high-carb, low-fat messaging, Mike presents a compelling case for the transformative power of low-carb, high-fat diets in combating the modern epidemics of obesity, diabetes, and other ailments stemming from the Western diet. Drawing from years of clinical experience and evidence-based research, Mike reveals the profound impact that adopting a low-carb, high-fat lifestyle can have on overall health and well-being. Through engaging anecdotes and expert insights, we explore how this dietary approach not only addresses weight management but also mitigates chronic inflammation, stabilizes blood sugar levels, and enhances cognitive function. Contrary to popular belief, Mike dispels myths surrounding fat consumption and unveils the numerous health benefits associated with incorporating healthy fats into our diets. Whether you're a skeptic or a seasoned advocate, this episode will challenge your preconceptions and empower you to make informed choices about your dietary habits. Tune in as we delve into the science behind low-carb, high-fat diets, discuss practical strategies for implementation, and navigate the potential pitfalls along the way. Discover why the paradigm shift towards embracing fat as a friend, rather than foe, is revolutionizing the way we approach nutrition and wellness. Prepare to be inspired, educated, and equipped with the knowledge to embark on your own journey towards optimal health and vitality. Don't miss this enlightening conversation with Mike Sweeney, as we uncover the untapped potential of low-carb, high-fat diets in transforming lives and reshaping our understanding of dietary norms.
Watch the full video interview on YouTube here: https://youtu.be/tN9o1oBDX-M Dr. Cate Shanahan (IG: @drcateshanahan) is a board certified Family Physician whose books have taught a generation of ancestral health influencers and nutrition-oriented MDs about the benefits of bone broth, organ meats, fermented foods and the damaging effects of a collection of 8 common oils (The Hateful 8) that she believes to be the ingredient in the Western Diet most responsible for obesity and inflammatory disease. Today's chat is focused on her New York Times bestselling book, The Fatburn Fix: Boost Energy, End Hunger, and Lose Weight by Using Body Fat for Fuel. In this episode, we discuss: Vegetable oils are toxic! The Hateful 8 Seed oils cause chronic disease Mitochondria and polyunsaturated fatty acids (PUFAs) Sugar is not causing diabetes The beginning of insulin resistance The problem with omega-6 and omega-3 fatty acids Should we aim to consume more omega-3s? How to eliminate seed oils from your body Hypoglycemia is a warning sign Practical steps to heal your mitochondria Chia seeds are high in PUFAs Beware: sources of seed oils Seed oil free food recommendations Dr. Cate's thoughts on plant toxins The truth about saturated fat Why Dr. Cate started focusing on seed oils 24 years ago High LDL is actually good for you It's time to stop snacking Learning to cook is empowering The misconceptions about ketones Is the carnivore diet healthy long term? How to eat more organ meats The best and worst supplements What is liver support? Stop fearing salt Show Sponsor: Quicksilver Scientific
This week we talk about CAR Ts, lupus, and antigen-presenting cells.We also discuss Hashimoto's, potential cures, and allergies.Recommended Book: The Avoidable War by Kevin RuddTranscriptChimeric antigen receptors, usually shorthanded as CARs, are a type of protein structure that receives and transmits signals within biological systems.The term "CAR T cell" refers to chimeric antigen receptors that have been altered so that these structures can give T cells, which are a component of the human body's immune system, attacking stuff that our immune systems identify as being foreign or otherwise potentially harmful, it gives these T cells the ability to target specific antigens, rather than responding in a general sense to anything that seems broadly off.So while T cells are generally deployed en masse to tackle all sorts of issues all throughout our bodies all the time, CAR T cells can tell them, hey, see this specific thing? This one thing I'm pointing at? Go kill that thing. And then they do.The potential to use CAR Ts for T cell-aiming purposes started to pop up in scientific literature in the late-1980s and early-1990s, and in the mid-90s there was a clinical trial testing the theory that T cells could be guided in this way to targeted cells throughout the body that are infected with HIV.That clinical trial failed, as did tests using CAR T approaches to sic T cells on solid tumors; there just didn't seem to be enough persistence in the T cells, in their targeting, to do much good in this regard.Second-generation CARs improved upon that original model, and that led to tests with more follow-through, better focus for those guided T cells, basically, and that improved their capacity to clear solid tumors in tests.By the early 2010s, researchers were able to completely clear solid cancers from patients, leading to complete remissions in some of them, though those patients were also treated with more conventional therapies beforehand.These new approaches led to the first two FDA-approved CAR T cell treatments in the US in 2017, for a type of leukemia and a type of lymphoma.As of late-2023, there were six such treatments approved for use by the FDA, most of them leveraged only for cancer patients who didn't respond well to conventional treatments, or who continued to relapse after several rounds of cancer therapy. It's a last line of defense, at this point, in part because it's still relatively new, and in part because the current collection of CAR T therapies seem to work best when the cancers have already been weakened by other sorts of attack.What I'd like to talk about today is another potential use for this same general technology and therapy approach that, until recently, was considered to be a really pie-in-the-sky sort of dream, but which is rapidly becoming more thinkable.—There's a theory that essentially all human beings have some kind of immunodeficiency: something that our immune systems don't do well, don't do at all, or don't do in the expected, baseline way.Any one of those immunodeficiency types can result in issues throughout a person's life, ranging from a higher-than-normal susceptibility to specific infections to a tendency to accidentally target healthy cells or biota, which can then result in all sorts of secondary issues for the host of those cells or biota.One especially pernicious and increasingly common issue in this space is what's called autoimmunity, which refers to the tendency of one's immune system to attack one's own cells and tissues and organs.If these autoimmune attacks are substantial and consistent enough, they can cause a disease in the afflicted body components, and diseases caused in this way are called autoimmune diseases.You've almost certainly heard of some of the more common of these diseases:Lupus, for instance, varies in its specifics, but arises when someone's immune system attacks their skin or muscles or joint tissues or components of their nervous system, resulting in an array of problems that has earned this disease the categorization as a "great imitator" condition, because it replicates the symptoms of a slew of other diseases and disorders.Folks with celiac disease experience all sorts of gut issues, primarily centralized in the small intestine, that disallow the comfortable and healthful consumption of gluten, which is present in all sorts of foods and which, if consumed, can cause incredibly uncomfortable and painful side effects, alongside other gut-related problems.Type 1 diabetes is an autoimmune disease, as is multiple sclerosis, rheumatoid arthritis, Addison's disease, Grave's disease, and Hashimoto's thyroiditis, in which one's immune system slowly destroys one's own thyroid, causing all sorts of problems, including, potentially, hypothyroidism and sometimes a rare type of cancer called thyroid lymphoma.All of these issues are associated with a variety of other issues beyond their initial, simplified portfolio of symptoms because our bodies are ecosystems, all the things connected to all the other things, so it's borderline impossible to tweak one thing without causing ripples throughout the rest of the system.If part of that system attacks another part of the system, then, there will be waves of long- and short-term consequences resulting from both the attack and the damage caused by the attack, so these issues, though in some cases quite mild, depending on the person who has them, can also flare-up periodically, after being triggered by something or for no apparent reason, and they can change in nature over time, perhaps seeming like nothing, flying under the radar most of our lives, until one day they pop up out of the woodwork, wreaking all sorts of havoc that can be debilitating and terrifying, especially since the person experiencing those issues generally doesn't know what's happening and may initially attribute them to something else.I actually speak with experience in that regard, as I have Hashimoto's, and only found out about it a few years ago—and it took nearly a year to figure out what was suddenly causing all sorts of health problems that seemed to arise from nowhere, but which were apparently lurking there, waiting to crest the surface of awareness, for the thirty-plus years it took me to reach that point.So autoimmune diseases are varied but stem from the same core issue of our immune systems attacking some component of the bodies they're meant to defend, and though the majority of such disordered immune system behaviors will lead to nothing, causing no damage and possibly being counteracted by some other component of our complex internal ecosystems, some cause damage leading to disease, and some of those diseases are significant and life-altering or life-threatening.About 50 million Americans have one of the more than 100 tracked autoimmune diseases, and it's estimated that something like 4% of the total human population has at least one autoimmune disease, though methods of identifying and tracking such things are imperfect, and methods for doing so vary greatly from country to country.It's long been known that women suffer from a lot more and more intense autoimmune diseases than men—about 80% of people who have autoimmune diseases are women—and the results of recent research suggest this may be because a molecule called Xist (which deactivates one of a woman's two X chromosomes, preventing the dangerous overproduction of proteins in their bodies) seems to play a role in the production of molecular complexes that are linked to a lot of the autoimmune diseases we track, those complexes triggering chemical responses that spark the cascade of other issues that then result in autoimmune problems.This is still very new science and a lot of the more thorough looks into the Xist molecule have been in mice, so far, so while some exploration of this same process has been done in humans, this is still pretty speculative right now.That said, better understanding this molecule and its triggers, and other potential, similar triggers, might someday help us bypass or reduce the influence of those chemical responses, which could in turn reduce the incidence or impact of these diseases.For the foreseeable future, though, we'll probably be plagued, on a significant scale, by autoimmune diseases. And the number of people suffering from these things seems to be going up; there's some evidence that folks are more prone to some autoimmune diseases after being infected with COVID-19, which suggests there might be a long-term infection component of these sorts of issues, with the viruses and bacteria we encounter over the course of our lives messing with our bodily functions just enough to tweak the variables that inform our autoimmune behaviors, sometimes permanently and negatively.But incidences of autoimmune disease have been on the rise for years, and there's some evidence that points at what we might call the Western Diet and its spread around the world for some of this increase, as the real uptick began about 40 years ago, when the American version of the Western Diet started to go global in a big way, and in the wake of that spread we've seen inflammatory bowel disease surge in the Middle East and Asia, along with the seeming export of Type 1 Diabetes, multiple sclerosis, and rheumatoid arthritis across parts of the world that had never really seen them on any scale before, but which, after the installation of a bunch of McDonalds and the introduction of highly processed foods to global supermarkets, began to show up in a big way.This is also still pretty speculative, so take this with a grain of salt, and it's also worth noting that environmental variables like the food we eat is only one component of this issue, even if a more direct causal relationship could be proven: you can eat nothing but ultra processed foods and never develop and autoimmune disease, and you can eat a perfect whole foods diet and develop one; none of these seeming amplifiers are being flagged as absolute causes: this seems to be something we're prone to, regardless, and the way we live and how we eat and maybe even the microsplastics in our environments are maybe tweaking the likelihood of autoimmune predispositions becoming autoimmune issues—they're probably not sparking the potential for those issues out of whole cloth, though, based on what we currently know, at least.Whatever's causing or fanning the flames of this increase in autoimmune issues, though, a recent series of announcements is becoming more significant as those numbers increase.Therapies based on research that was initially conducted back in the early 2000s suggest that it may be possible to either kill or dampen the impact of the cells that attack our own bodies as part of an autoimmune disfunction.It was reported back in 2022 that five people suffering from a severe autoimmune disease had those diseases driven into remission by a therapy that uses CAR T cells to tell the body to attack the patient's B cells, which in the case of these patients, were the cells responsible for their lupus.So this therapy programmed some of their T cells to attack their B cells, which were causing their symptoms, including lung inflammation, fatigue, arthritis, and fibrosis of their heart valves, and those symptoms then cleared up; the attacks stopped, and so did their symptoms.Even more interesting is that once the B cells were wiped out, the ones behaving badly, the therapy was halted, their B cells populations started to tick back up because the T cells stopped attacking them, but the new B cells didn't engage in the damaging behavior—they did what they were supposed to do, rather than attacking their host.The subjects' immune systems were also tested, as the researchers didn't want solve one problem but cause another, impairing their patents' immune systems in such a way that they were then prone to all sorts of other infections.That didn't seem to be the case: their immune responses were similar to those of other people, and that led them to conclude that the reprogrammed T cells were primarily targeting the bad B cells, not wiping out the whole of their immune functionality; which was a real issue with earlier versions of this concept which were tested about five decades ago, most of which basically demolished a patients' immune system and hoped for the best, leading to unfortunately predictable and terrible outcomes.In the year or so since that initial trial was conducted, ten more people have had their severe autoimmune diseases forced into remission by this approach, and there's now hope that it might also work on other such conditions, beyond the three that it has been shown to work on, so far. There's another, related approach being tested that aims to help the body develop a better sense of self-awareness, boosting its tolerance for what it wrongly perceives to be bad stuff, so that it doesn't have such a hair-trigger for attacking things it thinks are dangerous and foreign, slowly but surely upping the cap for attack until it no longer does so, or doesn't at a level that causes diseases symptoms.One approach to achieving this outcome uses a synthetic versions of what're called antigen-presenting cells, which pop around our bodies picking up little bits of antigens—which are detritus like chemicals and bacteria and pollen and so on, stuff that isn't part of us—and then they meet up with our T cells and tell them which of these things should be attacked, and which should be ignored because they're safe.The synthetic version of this system sends in nanoparticle replications of these antigen-presenting cells, using them to flag the stuff that's being errantly attacked as good, changing the T cells' opinion of those things over time, basically, but it's also possible to achieve something of the same by manipulating how the natural antigen-presenting cells operate.It may also be possible to use these signifiers to tell the T cells to attack the B cells, in the case of wanting to help folks with certain types of lupus, for instance, accomplishing what those other therapies accomplish but via different, less-invasive and more straightforward means.What we're seeing right now, then, is a change in how we think about autoimmune diseases and what causes them, and we're taking recent research and understandings about the mechanisms of how this stuff functions and trying to decide how best to recalibrate and even hijack those mechanisms to correct for issues in the system; the idea being to tweak one small thing, perhaps just once, and to consequently permanently change how the system functions in favor of healthier, happier outcomes.We are still at the beginning stages of this, but the pace at which these sorts of therapies are being developed and moved to clinical trials is heartening.It's possible that at some point in the next decade or two we could see commonly available treatments for things like lupus and Hashimoto's, which would be great, in my 100% biased opinion, but also for related issues like allergic reactions, which would make use of the same general theory and process to tell our immune systems not to freak out when they're exposed to, for instance, peanut proteins or pollen, changing the lives of even more people, as long as we can figure out how best to consistently and safely administer these therapies to folks who currently suffer from such things.Show Noteshttps://www.cell.com/cell/fulltext/S0092-8674(08)00624-7https://www.frontiersin.org/articles/10.3389/fimmu.2018.02359/fullhttps://www.nejm.org/doi/10.1056/NEJMc2107725https://www.science.org/doi/10.1126/science.1142963https://www.nature.com/articles/s41584-023-00964-yhttps://www.theguardian.com/science/2022/jan/08/global-spread-of-autoimmune-disease-blamed-on-western-diethttps://www.washingtonpost.com/science/2024/02/01/why-women-have-more-autoimmune-diseases/https://www.scientificamerican.com/article/autoimmunity-has-reached-epidemic-levels-we-need-urgent-action-to-address-it/https://archive.ph/0outqhttps://www.nature.com/articles/d41586-024-00169-7https://pubmed.ncbi.nlm.nih.gov/25277817/https://www.theguardian.com/science/2022/sep/15/scientists-hail-autoimmune-disease-therapy-breakthrough-car-t-cell-lupushttps://www.biopharmadive.com/news/crispr-cancer-cell-therapy-autoimmune-lupus/701528/https://www.wsoctv.com/news/trending/fda-issues-warning-secondary-cancer-risk-linked-car-t-therapies/RPAPN44ZCRFWFOROZOZLG2ZKG4/https://www.cancer.gov/about-cancer/treatment/research/car-t-cellshttps://www.nytimes.com/2024/01/23/health/fda-cancer-car-t-warning.htmlhttps://phys.org/news/2024-01-nanoparticles-anaphylaxis-side-effects-mouse.htmlhttps://hillman.upmc.com/mario-lemieux-center/treatment/car-t-cell-therapy/fda-approved-therapieshttps://en.wikipedia.org/wiki/CAR_T_cellhttps://en.wikipedia.org/wiki/Engineered_CAR_T_cell_deliveryhttps://en.wikipedia.org/wiki/Cellular_adoptive_immunotherapy#Chimeric_Antigen_Receptor_(CAR)_T_Cell_Therapy This is a public episode. 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The Real Truth About Health Free 17 Day Live Online Conference Podcast
We are diving into all things lipids, their classifications, and their profound impact on cell membranes, insulin resistance, diet changes, and overall health. Included in the discussion: the critical balance between omega-3 and omega-6, providing valuable tips for maintaining a healthy lipid profile, becoming aware of lipid oxidation, and avoiding those sources of oxidized lipids. Topics: 1. Introduction - Discussion on Cell Membranes, Seed Oils, Lipid Classification, and Insulin Resistance 2. Lipid Classification - Overview of Lipids - Fatty Acids - Triglycerides - Phospholipids 3. Cell Membrane Composition - Lipid Bilayer - Primary Lipids in Cell Membrane - Phosphatidylcholine (PC) - Phosphatidylethanolamine (PE) 4. Impact of Omega-6 on Cell Membrane - Disruption of Lipid Packing - Increased Membrane Rigidity - Impaired GLUT4 Transporters and Insulin Resistance - Effects on Insulin Receptor Signaling 5. Omega-3 vs. Omega-6 in Membrane Fluidity - Location of Double Carbon Bonds - Omega-3 Supporting Fluidity and Signaling 6. Insulin Resistance and Omega-6 Intake - Inverse Relationship with Linoleic Acid - Ideal Omega-6 to Omega-3 Ratio (4:1) - Western Diet's High Omega-6 Ratio (16:1) 7. Tips for Balancing Omega-6 and Omega-3 - Grass-Fed (and Finished) vs. Grain-Fed Meat - Avoiding Seed Oils - The Importance of Avoiding Oxidized Lipids 8. Oxidation of Lipids - Susceptibility of PUFAs to Oxidation - Cooking with Stable Fats (Saturated, Monounsaturated) - Need for Whole Foods and Home Preparation 9. Specifics on Flaxseed - Omega-3 Profile and Susceptibility to Oxidation - Recommendations for Usage and Storage 10. Conclusion and Future Topics - Mention of Future Episode on Mitochondrial Function and "detoxing your membranes" of these lipids Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Brian Clement Discusses Dangers of the Western Diet. French Fries Study, Causes of Cardiovascular Diseases, Projected Rates of Diabetes, and Obesity, Rising Trend of Cancer Rates, and lifestyle choices can potentially turn on genes that invite cancer Dr. Brian Clement, Ph.D., L.N., delves into the consequences of modern-day lifestyle choices on our health. Highlighting a surge in cardiovascular diseases, type 2 diabetes, obesity, and cancer, he underscores the grave implications of a sedentary lifestyle, unhealthy diets, and the byproducts of industrialization. Drawing on his extensive clinical experience and recent scientific studies, Dr. Clement emphasizes the significance of epigenetics, where our choices can shape our health more than our genetics. It's a wake-up call to reassess our habits and make informed decisions for a healthier future. #LifestyleChoices #Epigenetics #HealthAwakening
Thyroid Talk with Dr. Angela Mazza, DORecorded: November 10, 2023SHOW NOTES EPISODE 24Food Categories and InflammationHost: Dr. Angela Mazza, DOCo-host: Dawn SheffieldI'm Dr. Angela Mazza, D.O., a thyroid, endocrine, and metabolism specialist with a private practice in Central Florida. My goal for this podcast is to define and demystify the thyroid gland, and thyroid-related medical conditions. By providing information in an easy-to-understand format, we hope to help patients better understandthe ways in which their bodies work, and to help them thrive. My goal is to help us live more fulfilling lives by taking control of our health, to feel our best. I do this podcast to provide life-saving education and encourage patients to see a doctor in time to prevent or minimize damage. That's deeply fulfilling. I enjoy helping folks understand how all aspects of their lives are tied to both thyroid and overall health. That's why I went into endocrinology. It's a medical art that combines science with the study of our lives—and all that they encompass.To recap just some of what we covered in this episode, not necessarily in this order:Unprocessed, processed, and ULTRA-processed foods, defined;Making healthy food decisions;The NOVA food classification system;The dreaded Leaky Gut connection;Metabolism, weight, and health effects of food choices;And best of all, we learned that we CAN impact our thyroid health!Dr. Mazza's book, Thyroid Talk: An Integrative Endocrinologist's Guide to Optimal Thyroid Health is now available on Amazon. For information on the related Webinar and an online master course, go to birthabook.com/drmazza. Regarding supplements mentioned in various episodes of this podcast, please visit the Wellness Store at metaboliccenterforwellness.com. Send your comments, show ideas, and questions for future episodes to thyroidtalk.mazza@gmail.com We may disclose your general location on air (the city or town, for example), but we will NOT read your name NOR your address on the show. We reserve the right to edit your input as necessary. Please stay in touch! Check us out on YouTube, the website at metaboliccenterforwellness.com, as well as Facebook, Instagram, and TikTok. Our next episode—number 25—will cover both local and international listeners' questions, comments, and suggestions! PS: Part 3 on Leaky Gut coming soon, too! Listeners can't get enough!Citations, references, additional information for SHOW NOTES: Montiero CA, Cannon G, Levy RB et al. NOVA. The star shines bright. World Nutrition 2016;7, 1-3, 28-38.Hall KD, et al. Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake. Cell Metab. 2019 Jul 2;30(1):67-77.e3.Healthline.com “What's the Difference Between Processed and Ultra-Processed Food?” Medically reviewed by Sade Meeks, MS, RD Nutrition -- By Sarah Garone -- Updated on May 8, 2023.Mazza A. Thyroid Talk: An Integrative Endocrinologist's Guide to Optimal Thyroid Health. Now available; please look for it on Amazon.Shi Z. Gut Microbiota: An Important Link between Western Diet and Chronic Diseases. Nutrients. 2019 Sep 24;11(10):2287. doi: 10.3390/nu11102287. PMID: 31554269; PMCID: PMC6835660.Zhang J, et al. Ultra-processed food consumptionCheck out our YouTube channel - Dr. Angela Mazza, our website at Metabolic Center for Wellness, our FaceBook and our Instagram page.
Join us as we explore the world of gut health and wellness with the medical maverick, Dr. Leo Galland. Renowned for his innovative nutritional therapies, Dr. Galland shares his secrets to treating autoimmune, inflammatory, and gastrointestinal disorders. Discover how the uniqueness of each patient plays a pivotal role in treatment, and why understanding a patient's family, background, genetics, and life experiences can make all the difference.Get ready to unlock the fascinating interplay between nutrition and health. After years of studying nutrition and behavioral medicine, Dr. Galland reveals the potential of nutrition to support gut health and improve our behavior. Discover the clinical importance of microbiome research, the factors and tests for gut health, and the influence of our gut microbiome on our behavior. Don't miss out on his unique dietary supplement, TLC, designed to revolutionize our approach to wellness.Lastly, uncover the power of therapeutic whole foods and health supplements. Dr. Galland explores the benefits of black cumin seed oil, Luteolin, and curcumin and how they can act as sculptors in our microbiome. Learn about the significance of a high-fiber, low-sugar, and high-polyphenol diet, and how to balance the challenges of legume consumption. From the role of the gut microbiome in our behavior to the keys to longevity, join us for a journey that could redefine your approach to health and wellness.Episode Chapters:(0:00:01) - The Vibrant Wellness Podcast(0:10:12) - Effects of Nutrition on Health(0:18:01) - The Clinical Importance of Microbiome Research(0:22:19) - Factors and Testing for Gut Health(0:38:57) - Microbiomes, Nutrition, and Human Behavior(0:44:34) - Therapeutic Whole Foods and Health Supplements(0:59:40) - Key to LongevityLinks:Dr. Galland's websiteJoin Over 18,000 Leading Medical Professionals and Become a Vibrant Wellness Provider Today!
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.21.550120v1?rss=1 Authors: Hayes, A. M. R., Tierno Lauer, L., Kao, A. E., Sun, S., Klug, M. E., Tsan, L., Rea, J. J., Subramanian, K. S., Gu, C., Tanios, N., Ahuja, A., Donohue, K. N., Decarie-Spain, L., Fodor, A. A., Kanoski, S. E. Abstract: Western diet (WD) consumption during development yields long-lasting memory impairments, yet the underlying neurobiological mechanisms remain elusive. Here we developed an early life WD rodent model to evaluate whether dysregulated hippocampus (HPC) acetylcholine (ACh) signaling, a pathology associated with memory impairment in human dementia, is causally-related to WD-induced cognitive impairment. Rats received a cafeteria-style WD (access to various high-fat/high-sugar foods; CAF) or healthy chow (CTL) during the juvenile and adolescent periods (postnatal days 26-56). Behavioral, metabolic, and microbiome assessments were performed both before and after a 30-day healthy diet intervention beginning at early adulthood. Results revealed CAF-induced HPC-dependent contextual episodic memory impairments that persisted despite healthy diet intervention, whereas CAF was not associated with long-term changes in body weight, body composition, glucose tolerance, anxiety-like behavior, or gut microbiome. HPC immunoblot analyses after the healthy diet intervention identified reduced levels of vesicular ACh transporter in CAF vs. CTL rats, indicative of chronically reduced HPC ACh tone. To determine whether these changes were functionally related to memory impairments, we evaluated temporal HPC ACh binding via ACh-sensing fluorescent reporter in vivo fiber photometry during memory testing, as well as whether the memory impairments could be rescued pharmacologically. Results revealed dynamic HPC ACh binding during object-contextual novelty recognition was highly predictive of memory performance and was disrupted in CAF vs. CTL rats. Further, HPC alpha-7 nicotinic receptor agonist infusion during consolidation rescued memory deficits in CAF rats. Overall, these findings identify dysregulated HPC ACh signaling as a mechanism underlying early life WD-associated memory impairments. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Join Jon Macaskill, a retired Navy SEAL turned mindfulness teacher, and his cohost, renowned NYC Yoga and mindfulness guru Will Schneider, as they revisit an enlightening episode of "Men Talking Mindfulness." In this replay, they interview Dr. Uma Naidoo, author of the groundbreaking book "This Is Your Brain on Food," diving deep into the fascinating world of the mind-gut connection. Dr. Naidoo, a leading expert in nutritional psychiatry, unravels the profound impact of food on our mental health and well-being. Discover the intricate relationship between what we eat and how it affects our mood, cognition, and overall brain function. Her wealth of knowledge and clinical experience sheds light on the transformative potential of a mindful and nutritious diet. In this captivating conversation, Dr. Naidoo shares valuable insights on the connection between gut health, inflammation, and mental disorders such as anxiety and depression. Gain a deeper understanding of the role of specific nutrients, gut bacteria, and dietary patterns in promoting optimal brain function and emotional balance. Through the fusion of Jon Macaskill and Will Schneider's expertise in mindfulness and Dr. Naidoo's scientific expertise, listeners will learn practical strategies for incorporating mindful eating habits into their daily lives. Discover how to cultivate a mindful relationship with food, make informed dietary choices, and experience the profound impact of nourishing both the body and mind. Join the Men Talking Mindfulness community and embark on a transformative journey, exploring the powerful influence of food on our brain health and emotional well-being. Empower yourself with the knowledge and tools to optimize your mind-gut connection, leading to a healthier, more balanced life. Follow Dr. Naidoo on Instagram here: @drumanaidoo Learn more about her, her book, and her online class here: https://umanaidoomd.com (01:00) This is Your Brain on Food with Guest Dr. Uma Naidoo (03:00) Introducing Dr. Uma Naidoo (04:30) Will leads Opening Grounding Practice (~3 minutes) (07:00) Dr. Naidoo's journey to Nutritional Psychology (11:00) The Neuroscience of the Mind/Gut Connection (15:00) The Western Diet is S.A.D. (17:00) What is a microbiome and why you should care (21:30) Diet as a solution to illness and disease (25:00) Caffeine - Friend or Foe? (26:30) Calculating Alcohol Consumption, or why you needed math class (29:00) Hang-xiety = Hangover + Anxiety (32:00) Proactive vs Reactive ways to deal with Anxiety (35:00) When sugar isn't sugar (37:00) Processed foods are depressing in so many ways (39:30) Food Fog is Real (42:30) Micronutrients as medicine (45:30) Omega-3s are super brain fuel (50:00) One thing you can do today (52:00) Add a little spice to your life (56:30) Jon leads Closing Grounding Practice (~2 minutes) Opening and closing Music: Malecon by Soyb & Amine Maxwell https://soundcloud.com/soybmusic https://soundcloud.com/aminemaxwell Creative Commons — Attribution 3.0 Unported — CC BY 3.0 Free Download / Stream: https://bit.ly/al-malecon Music promoted by Audio Library https://youtu.be/xbWzYbtMgIE Keywords: mindfulness, mind-gut connection, Dr. Uma Naidoo, book, "This Is Your Brain on Food," Navy SEAL, mindfulness teacher, Yoga, mental health, well-being, nutrition, dietary patterns, gut health, inflammation, anxiety, depression, mindful eating, brain function, emotional balance, Jon Macaskill, Will Schneider.
In this sixth episode of Morning Sign In, Morning Sign Out (MSO) Outreach Director Jenny Lee, writer Audrey Banzali-Marks, and editor Hope Harris talk about the latest research on the relationship between eczema and dietary fiber, as well as how the modern Western Diet could affect our health based on the researchers' results. Audio editing: Jenny Lee, Outreach Director Speakers: Jenny Lee, Outreach Director; Audrey Banzali-Marks, Writer; Hope Harris, Editor MSO Website: https://www.msoatucla.org/ Audrey Banzali-Marks' Article: https://www.msoatucla.org/feeding-the-fight-against-eczema-how-fiber-strengthens-skin.html Trompette et al.'s Research: https://www.sciencedirect.com/science/article/pii/S1933021922000113?via%3Dihub Other sources used in this episode: National Eczema Association Website: https://nationaleczema.org/eczema/ National Eczema Association's eczema statistics: https://nationaleczema.org/research/eczema-facts/ Medline Plus' carbohydrate information: https://medlineplus.gov/carbohydrates.html The Harvard School of Public Health's information on dietary fiber recommendations: https://www.hsph.harvard.edu/nutritionsource/carbohydrates/fiber/ Mayo Clinic's information on symptoms of insufficient dietary fiber in the diet: https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/fiber/art-20043983#:~:text=Dietary%20fiber%20increases%20the%20weight,Helps%20maintain%20bowel%20health. Nemours Children's Health information on keratinocytes: https://kidshealth.org/en/parents/skin-hair-nails.html#:~:text=Keratinocytes%20(ker%2Duh%2DTIH,protect%20the%20body%20against%20infection. Rakhra et al.'s information on the Western Diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721435/ Bylund et al.'s information on the prevalence and incidence of atopic dermatitis: https://medicaljournalssweden.se/actadv/article/view/1691 National Eczema Association's information on eczema diets: https://nationaleczema.org/diet-nutrition/
So, the question is.. is your kids current diet impacting their mood, behaviour and mental health? The answer is YES! The relationship between food and mood is a two-way street. What you eat affects your mood, and your mood can affect your food choices. In this episode I will be discussing: The research studies that confirm the impact food plays on managing moods, plus the diet that is seeing positive results in managing mood disorders;Brain nutrition and the vital micronutrients you need to be getting into your kids to support their brain and help manage their moods;The impacts of inflammation;The gut-brain connection, and the implications that poor gut health can have on your kids mood;How breakfast can improve your kids mood & behaviour. Episode Links:Check out the research papers via our blog post here.Get on top of your kids mood and behaviour via a 1:1 consultation with our practitioners. Click here to book.
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The Rise And Spread Of Autoimmune Disease Has Exactly Mirrored The Rise And Spread Of The Western Diet Dr. Brooke Goldner • http://www. goodbyelupus.com • Book – Goodbye Lupus #BrookeGoldner #Lupus #AutoimmuneReversal Dr. Brooke Goldner is a board-certified physician, the founder of GoodbyeLupus.com And She is the creator of the Hyper-nourishing Protocol for Autoimmune Reversal. She is the author of 3 bestselling books, Goodbye Lupus, Goodbye Autoimmune Disease, and Green Smoothie Recipes to Kick-Start Your Health and Healing. Her most recent book Goodbye Autoimmune Disease In this sequel to Goodbye Lupus, Dr. Brooke Goldner details how she used her hyper-nourishment protocol to help real people all over the world get their lives back from Lupus, Rheumatoid Arthritis, Sjogren's, Scleroderma, Psoriasis, Hashimotos and many more using supermarket foods. She also dives deeply into the mindset needed to change your diet and take back your health including motivation, overcoming self-sabotage, and embracing health and happiness. This book will get you inspired, prepared, and excited to take back your health. You will learn: * The 6 Steps to Reversing Disease with Supermarket Foods * How to get relief from pain, brain fog, inflammation, and chronic fatigue so you can feel alive again *How your mindset can keep you sick and also be the key to reversing your autoimmune disease *How to turn getting healthy into a habit *How to stop sabotaging yourself on your disease-reversal nutrition plan *How to conquer health anxiety *Learn from numerous case studies of real people who changed their lifestyle and their diet and were able to heal from Lupus, Scleroderma, Rheumatoid Arthritis, Sjogren's, Mixed Connective Tissue Disease, Nephritis, Hypothyroid, Psoriasis, Multiple Sclerosis, and Chronic Pain. And much, much more. She has been featured in multiple documentaries such as Eating You Alive, Whitewashed, and The Conspiracy Against Your Health, has been featured on tv news and the Home & Family Show, as well as many radio shows and podcasts, and is a highly sought-after keynote speaker. She has been featured on the front cover of Vegan Health & Fitness Magazine 3 times, including the recent cover of Fit Over Forty. She is a regular contributor to T. Colin Campbell Center for Nutrition Studies, and she is featured in the Journal of Disease Reversal reversing lupus in herself, as well as multiple cases studies in reversing end-stage lupus nephritis (kidney failure) with her hyper-nourishing nutrition protocol. She graduated Carnegie Mellon University with honors for genetic research in leukemia and neurobiology, was a graduate of the Temple University School of Medicine, was Chief Resident at UCLA-Harbor Residency, and holds a certificate in Plant-Based Nutrition from Cornell University. To Contact Dr Goldner go to goodbyelupus.com Disclaimer:Medical and Health information changes constantly. Therefore, the information provided in this podcast should not be considered current, complete, or exhaustive. Reliance on any information provided in this podcast is solely at your own risk. The Real Truth About Health does not recommend or endorse any specific tests, products, procedures, or opinions referenced in the following podcasts, nor does it exercise any authority or editorial control over that material. The Real Truth About Health provides a forum for discussion of public health issues. The views and opinions of our panelists do not necessarily reflect those of The Real Truth About Health and are provided by those panelists in their individual capacities. The Real Truth About Health has not reviewed or evaluated those statements or claims.
Brain Health and Obesity are linked. What can you do?Grb10 offers a potential new approach for treating obesityWestern Diet Causes Cycle of Brain Damage and ObesityChildhood Obesity: Drugs and Surgery Top List of American Academy of Pediatrics New Guidelineshttps://www.georgebatista.comThe Wellness Company - https://www.twc.health/BatistaWellness Resources - http://www.myvitaminresource.com(Promocode: counterparts - For free shipping)https://bitchute.com/channel/yrUk4dKq...https://rumble.com/user/WellnessTalkhttps://www.brighteon.social/invite/i...https://open.spotify.com/show/5MvjsMT...https://apple.co/3H39DGKEmail:Wellnesstalk@protonmail.comWellness Resources Since 1985, Wellness Resources has used only the highest quality nutrients, no chemical additives, tDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showDisclaimer: The Wellness Talk podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
The WESTERN DIET is killing our bodies, energy levels, & even our ability to reproduce children. In 2022, there will be an estimated 1.9 million NEW CANCER cases diagnosed and 609,360 cancer deaths in the United States. Our next guest Dr. John M. Poothullil believes that if we can control our diet we can prevent or reverse many conditions that destroy our health such as OBESITY, HIGH BLOOD SUGAR leading to Type 2 diabetes, and even CANCER. No one understands this more than Dr. John, as 11 years ago he was surprisingly diagnosed with cancer. Dr. John M. Poothullil has devoted 20 years to studying diabetes and cancer and has written 5 books, all available on Amazon and in many bookstores. His articles have been published in medical journals such as Physiology and Behavior, Neuroscience and Biobehavioral Reviews, Journal of Women's Health, Journal of Applied Research, Nutrition, and Nutritional Neuroscience. We know training our mind is key, but fueling our body the right way is just as important. Listen to my interview with Dr. John Poothullil on Why Cancer Happens & Key Strategies For A Healthy Life. Connect with Dr. John Poothullil: Instagram: https://www.instagram.com/drjohnonhealth/ Website: https://www.drjohnonhealth.com/ Buy Surviving Cancer: A New Perspective on Why Cancer Happens & Your Key Strategies for a Healthy Life: https://www.amazon.com/Surviving-Cancer-Perspective-Happens-Strategies/dp/0998485020/ref=sr_1_2?s=books&ie=UTF8&qid=1517203975&sr=1-2&refinements=p_27%3AJohn+Poothullil++MD Thank you for watching this video—Please Share it and get the word out! What part of this video resonated with you the most? Comment below!
Now y'all know Western culture has the worst diet in the whole world, besides a Third World country …
The first time you sit down for a meal at the McDougall Health and Medical Center in Santa Rosa, California, be prepared for a shock. You'll be surprised at what's on the table, and what's not. Dr. McDougall himself explains.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Half The People On The Western Diet Are Prediabetic John A. McDougall, M.D. • http://www.drmcdougall.com• Book - The Starch Solution: Eat the Foods You Love, Regain Your Health, and Lose the Weight for Good! John A. McDougall, M.D. a physician and nutrition expert who teaches better health through vegetarian cuisine, John A. McDougall, MD has been studying, writing, and speaking out about the effects of nutrition on disease for over 50 years. Dr. John and Mary McDougall believe that people should look and feel great for a lifetime. Unfortunately, many people unknowingly compromise their health through poor dietary habits. Dr. McDougall is the founder and director of the nationally renowned McDougall Program: a ten-day residential program that he and Mary McDougall host at a luxury resort in Santa Rosa, CA where medical miracles occur through diet and lifestyle changes. In addition to her formal training as a nurse, Mary McDougall provides many of the delicious recipes that make the McDougall Program not only possible, but also a pleasure. Dr. McDougall has cared for thousands of patients for 5 decades. His program not only promotes a broad range of dramatic and lasting health benefits but, most importantly, can also reverse serious illnesses including high blood pressure, heart disease, diabetes and others, all without the use of drugs. #JohnMcDougall #TheRealTruthAboutHealth #WholeFood #Vegan #Vegetarian #PlantBasedNutrition CLICK HERE - To Checkout Our MEMBERSHIP CLUB: http://www.realtruthtalks.com Social Media ChannelsFacebook: https://www.facebook.com/TRTAHConferenceInstagram : https://www.instagram.com/therealtruthabouthealth/Twitter: https://twitter.com/RTAHealthLinkedin: https://www.linkedin.com/company/the-real-truth-about-health-conference/Youtube: https://www.youtube.com/c/TheRealTruthAboutHealth Check out our Podcasts Visit us on Apple Podcast and Itunes search: The Real Truth About Health Free 17 Day Live Online Conference Podcast Amazon: https://music.amazon.com/podcasts/23a037be-99dd-4099-b9e0-1cad50774b5a/real-truth-about-health-live-online-conference-podcastSpotify: https://open.spotify.com/show/0RZbS2BafJIEzHYyThm83JGoogle:https://www.google.com/podcasts?feed=aHR0cHM6Ly9mZWVkcy5zaW1wbGVjYXN0LmNvbS8yM0ZqRWNTMg%3D%3DStitcher: https://www.stitcher.com/podcast/real-truth-about-health-live-online-conference-podcastAudacy: https://go.audacy.com/partner-podcast-listen-real-truth-about-health-live-online-conference-podcastiHeartRadio: https://www.iheart.com/podcast/269-real-truth-about-health-li-85932821/Deezer: https://www.deezer.com/us/show/2867272 Other Video ChannelsYoutube: https://www.youtube.com/c/TheRealTruthAboutHealthVimeo: https://vimeo.com/channels/1733189Rumble: https://rumble.com/c/c-1111513Facebook: https://www.facebook.com/TRTAHConference/videos/?ref=page_internalDailyMotion: https://www.dailymotion.com/TheRealTruthAboutHealthBitChute: https://www.bitchute.com/channel/JQryXTPDOMih/ Disclaimer:Medical and Health information changes constantly. Therefore, the information provided in this podcast should not be considered current, complete, or exhaustive. Reliance on any information provided in this podcast is solely at your own risk. The Real Truth About Health does not recommend or endorse any specific tests, products, procedures, or opinions referenced in the following podcasts, nor does it exercise any authority or editorial control over that material. The Real Truth About Health provides a forum for discussion of public health issues. The views and opinions of our panelists do not necessarily reflect those of The Real Truth About Health and are provided by those panelists in their individual capacities. The Real Truth About Health has not reviewed or evaluated those statements or claims.
Healthy Mind for Happy Running Introduction Exercise and nutrition are known to play a role in developing and altering brain function and studies have shown that both exercise and nutrition could affect mind/mood and cognition positively and negatively. So, we: Outline some mind/mood symptoms runners may experience and why Discuss foods/nutrients that may induce negative or promote positive mood and mindset in runners Create a one-day meal plan you may wish to consider for a healthy mind and happy running SHOW NOTES (06:56) Discussing the positive endorphin effects of moderate running before moving on to outline the potential negative psychological effects of intense and/or prolonged running (10:51) Considering the potential drivers of detrimental mind/mood symptoms associated with endurance or intense running. (19:37) FEMALE FACTORS 1) The strain of mental health (and behavioural disorders) is estimated to account for more years of lived disability than any other chronic health ailment. From data collected between 2007 to 2017 the global proportion of disability-adjusted life years caused by mental ill-health has increased from: • Males: 12.7% to 14% • Females: 13.6% to 14.4% So, from these statistics, the years lived with mental ill health has increased for both men and women, however it would appear women are at increased risk of developing mental health issues besides men. 2) Female *obligatory (obsessive) runners are most at risk of eating pathophysiology than their male counterparts or non-obsessive runners 3) Commitment to running can occur without addiction in female runners but not in males NOTE: * Obligatory runners - obsessive runners who sacrifice commitments and relationships for running and suffer withdrawal symptoms if they miss a run (24:38) Highlighting potential dietary lifestyles that may enhance mental wellbeing or possibly be a driver of poor mind/mood and cognition symptoms with a focus on the common Western Diet and the Traditional Mediterranean Diet. (35:39) Exploring foods/meals to support positive mental wellbeing therefore enhance running performance Foods discussed include: Eggs, legumes, fermented foods, and a variety of vegetables. (43:53) KEY TAKEAWAYS Moderate running is known to be a therapeutic tool for different negative psychological conditions, such as: depression, anxiety, tension, mood changes and low self esteem However intense and/or prolonged running may lead to detrimental mind/mood symptoms in some people Our diet can also affect our emotions and cognitive function in a positive or detrimental way with the common Western Diet leading to low mood/cognition and the Mediterranean diet encouraging positive emotions and mindset A compromised immune system and a poor gut microbiome are thought to be the key drivers of low mood/cognition due to their influence on inflammation As well as affecting us physically, inflammation is known to affect: Energy, Sleep and Motivation….amongst other things Increasing intake of whole foods and following a traditional Mediterranean diet has been found to diminish many emotional/psychological symptoms such as low mood/depression/anxiety RELATED EPISODES: https://she-runs-eats-performs.captivate.fm/episode/Eat-Sleep-Run (Eat Sleep Run) https://she-runs-eats-performs.captivate.fm/episode/food-for-gut-healing (Food for Gut Healing) https://she-runs-eats-performs.captivate.fm/episode/endurance-running-and-immune-system (Endurance Running and the Immune System) Disclaimer: The suggestions we make during this episode are for guidance and advice only, and are not a substitute for medical advice or treatment. If you have any concerns regarding your health, please contact your healthcare professional for advice as soon as possible. Aileen Smith and Karen Campbell host https://my.captivate.fm/www.runnershealthhub.com (RUNNERS HEALTH HUB). A place...
Vielleicht hast du es herausgehört, letzte Woche habe ich es hier im Podcast angekündigt, denn wir werden in dieser Folge über das Thema Ernährung sprechen und dafür habe ich mir kompetente Hilfe geholt: Ich spreche mit meiner lieben Freundin Ele darüber, auf wie vielen Ebenen eine gesunde Ernährung für uns arbeitet und wirkt. Ich hatte mehrere AHA Erlebnisse und bin seit unserem Gespräch nochmal ganz anders und bewusst im Alltag und beim Kochen dabei und in der Auseinandersetzung mit mir selbst. Wir sprechen zusammen über Mikronährstoffe und Makronährstoffe, darüber wie wir bzw. wie unser Körper diese gut aufnehmen kann, worauf wir dabei achten müssen und was für Auswirkungen diese auf unsere psychische und körperliche Gesundheit haben. Es geht um die Western Diet, die Mediterranean Diet, um Nachhaltigkeit und Fair-Trade, um Biosiegel und warum dann Bio doch nicht gleich Bio ist und wie bei dem Ganzen auf unerwünschte Schadstoffe geachtet werden kann. Es gibt Kochtipps, Verarbeitungstipps und ganz viel gute Vibes! Ich wünsche euch viel Spaß mit dieser schönen Podcastfolge und ihr dürft gerne kommentieren und schreiben, wenn euch die Folge gut gefallen hat, ich werde es mit Ele teilen. Und über eine schöne Rezension bei Itunes oder Spotify freue ich mich sehr! Weitere Informationen findest du auf: www.karlajohannaschaeffer.com
In this episode we discuss obesity. The US is currently experiencing an epidemic of obesity, with over 40% of Americans grappling with this problem. But what is driving this obesity epidemic? Is it our Western Diet? Our sedentary lifestyles? Can obesity even be prevented or is it simply a matter of genetics? Can we overcome obesity? What has actually been shown to work? Diet? Exercise? Medications? And to what extent is obesity an expected outcome of the onslaught of food marketing vying for our attention every day from print, TV, and, of course, social media? In order to answer these questions and many more we turned to a true expert. Dr. Travis Masterson is the director of the Health, Ingestive Behavior, and Technology Lab (HIT Lab) at Penn State University where he is an Assistant Professor in the Nutrition department. Dr. Masterson earned his Bachelors and Masters Degrees in exercise science from Brigham Young University and the completed his PhD in Nutritional Sciences at Penn State University. He then served as a research fellow at Dartmouth University before returning to Penn State where his research focuses on environmental food cues and their effect on eating behavior. Dr. Masterson has written over 40 scientific manuscripts. He is also a spokesperson for the Obesity Society.
Join us today, learn all about how the western diet is making us unhappy, unhealthy, and weak. Dr Robert Lustig is a pioneer and advocate, author of "Fat Chance" and "Metabolical". You can learn more at his website and links below.Addicted to the western diet.Dr Lustig discusses on the podcast that certain foods — “hyperpalatable foods” — particularly processed foods that are high in sugar, salt and fat can be addictive. Food addiction is still a controversial concept in the scientific community. But researchers find strong evidence that certain foods can trigger binging, craving and withdrawal, responses that are similar to those produced by addictive substances like alcohol, cocaine and tobacco.Dr Lustig discusses that "Non-communicable diseases (NCDs) account for about 50% of the global disease burden and some 75% of total health-care spending. The role of processed foods in these chronic conditions is undisputed; every country that adopts the high-fat, high-sugar “Western pattern diet” is plagued by the same diseases and costs. But the big question for health professionals is whether the quantity or the quality of foods is to blame. This is an important distinction, because quantity is determined by the user, while quality is determined by the industry.Some health experts argue that specific components of processed foods – in particular, sugar – are as addictive as cocaine and heroin. For example, sugar is consistently the ingredient with the highest score on the Yale Food Addiction Scale, which measures people's food cravings.Not everyone who is exposed to sugar becomes addicted; but, as with alcohol, many do. While refined sugar is the same compound found in fruit, it lacks fiber and has been crystallized for purity. It is this process that turns sugar from a “food” into a “drug,” allowing the food industry to “hook” unsuspecting consumers. The evidence is visible in every aisle of every grocery store, where a staggering 74% of all food items are spiked with added sugar. In fact, sugar's allure is a big reason why the processed food industry's current profit margin is 5% (up from 1%), and why so many of us are sick, fat, stupid, broke, depressed, and just plain miserable".Dr. Robert Lustig is Professor of Pediatric Endocrinology at the University of California, San Francisco. Dr. Lustig has become a leading public health authority on the impact sugar has on fueling the diabetes, obesity and metabolic syndrome epidemics, and on addressing changes in the food environment to reverse these chronic diseases.In his New York Times best selling book Fat Chance: Beating the Odds Against Sugar, Processes Food, Obesity, and Disease, Robert documents both the science and the politics that have led to the current pandemic of obesity and chronic disease. In the Fat Chance Cookbook, Robert provides practical examples for applying healthy eating principles with recipes by Cindy Gershen.Dr. Lustig is a neuroendocrinologist, with basic and clinical training relative to hypothalamic development, anatomy, and function. Prior to coming to San Francisco in 20Support the show (https://www.patreon.com/selenab)
Professor Susan Carle of the Washington College of Law and AU Distinguished Professor of Neuroscience, Dr. Terry Davidson, discuss Davidson's research of on the connections between a diet high in saturated fats and sugars, sometimes called the Western diet, and deficits in learning and memory tasks and the regulation of food intake. Dr. Davidson discusses the implication of his findings for understanding obesity and behavioral excess such as drug abuse. Might there be common brain mech…
Dr. Uma Naidoo has been described as the world's first “triple threat” in the food and medicine space: a Harvard trained psychiatrist, Professional Chef graduating with her culinary schools' most coveted award, and a trained Nutrition Specialist. Her nexus of interests have found their niche in Nutritional Psychiatry. Dr. Naidoo founded and directs the first hospital-based Nutritional Psychiatry Service in the United States. She is the Director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital (MGH) & Director of Nutritional Psychiatry at MGH Academy while serving on the faculty at Harvard Medical School. She was considered Harvard's Mood-Food expert and has been featured in the Wall Street Journal. Dr. Naidoo is also the national best selling author of This Is Your Brain On Food. In her book, she shows the cutting-edge science explaining the ways in which food contributes to our mental health and how a sound diet can help treat and prevent a wide range of psychological and cognitive health issues, from ADHD to anxiety, depression, OCD, and others. Follow Dr. Naidoo on Instagram here: @drumanaidoo Learn more about her, her book, and her online class here: https://umanaidoomd.com 01:00 This is Your Brain on Food with Guest Dr. Uma Naidoo 03:00 Introducing Dr. Uma Naidoo 04:30 Will leads Opening Grounding Practice (~3 minutes) 07:00 Dr. Naidoo's journey to Nutritional Psychology 11:00 The Neuroscience of the Mind/Gut Connection 15:00 The Western Diet is S.A.D. 17:00 What is a microbiome and why you should care 21:30 Diet as a solution to illness and disease 25:00 Caffeine - Friend or Foe? 26:30 Calculating Alcohol Consumption, or why you needed math class 29:00 Hang-xiety = Hangover + Anxiety 32:00 Proactive vs Reactive ways to deal with Anxiety 35:00 When sugar isn't sugar 37:00 Processed foods are depressing in so many ways 39:30 Food Fog is Real 42:30 Micronutrients as medicine 45:30 Omega-3s are super brain fuel 50:00 One thing you can do today 52:00 Add a little spice to your life 56:30 Jon leads Closing Grounding Practice (~2 minutes) Opening and closing Music: Malecon by Soyb & Amine Maxwell https://soundcloud.com/soybmusic https://soundcloud.com/aminemaxwell Creative Commons — Attribution 3.0 Unported — CC BY 3.0 Free Download / Stream: https://bit.ly/al-malecon Music promoted by Audio Library https://youtu.be/xbWzYbtMgIE
Welcome to Low Carb Conversations with Leah Williamson and Holly Jean Mullen, Functional Nutritional Therapy Practitioners. In this episode, Leah and Holly Jean discuss contributing factors of autoimmune disease. For decades, doctors and researchers believed that autoimmune conditions were genetic, or hereditary, and even a normal side effect of the aging process. But as conditions are rising at alarming rates and the age of diagnosis is getting younger and younger, researchers are asking questions and exploring the reasons for autoimmune onset. We take a look at nutrition and lifestyle factors in this episode and discuss whether or not the western diet is to blame. If nutrition and diet play a role in developing autoimmune disease, is it possible to use therapeutic diets to reverse symptoms and diagnosis? We explore all this and more, in this episode! Article: Is the Western diet causing a spike in autoimmune diseases Doctor reverses autoimmune disease with diet Resources: AIP SUMMIT Dr. Sarah Ballantyne Dr. Terry Wahls Ways you can help support the Podcast! We are truly appreciative of any support you can give to the podcast! Here are some ways you can help us reach more people each week: SUBSCRIBE to the podcast (if you don't already) so it automatically downloads for you each week and you never miss an episode. REVIEW – Leave a review on Apple Podcasts – it does not take very long to do and this really helps get the podcast seen by others. RECOMMEND the podcast to your friends and family – recommendations from someone you know and trust are always invaluable. DONATE – If you love the show and our content, consider making a donation by clicking the “Donate” now Pay Pal button on the right side of the website. GET SOCIAL – Join the Facebook Group, like the Facebook Page, and NOW ON INSTAGRAM GO SHOPPING using any affiliate links we post if you are thinking of buying a book or product we mention or recommend. We appreciate you, our listeners, and your support of the podcast allows us to reach more listeners, book amazing guests, and spread the messages of honest nutrition, health, and wellness. Thank you so much! TRY the Nutritional Therapy 101 FREE 7 Day course and get a taste of what you can learn! Listen or subscribe with Siri or Alexa. Low-Carb Conversations Production by Kevin Kennedy-Spaien of Disc Of Light Media. Theme and interstitial music: Out of It (Rambling Man Remixes) by Andrew Bowden (c) copyright 2011 Licensed under a Creative Commons Attribution Noncommercial (3.0) license. http://dig.ccmixter.org/files/andrewbowden/33629 Ft: Brad Sucks
We're digging into how to move from the Standard American/Western Diet to a healthy diet for your fertility. Let's face it, eating a diet that is right for our fertility is confusing. Whether it's fertility superfoods, generalized recommendations about what to eat or avoid for optimized fertility… we may not know where to start. However, we all know that eating packaged processed foods is not healthy for anyone – especially if we are trying to conceive. Changing to a healthy preconception diet is not about deprivation or eating food that tastes like cardboard. It's about finding the most nutrient-dense foods that actually taste good so that you can prepare for a successful pregnancy. And it's not a “diet” – it's a lifestyle change that literally is life-changing – our clients tell us so! You have your WHY, so let's get started. I'm excited to welcome Justine Altman back to the podcast. Justine is part of my team here at Fab Fertile. She is an integral part of our Couples Coaching program - which uses functional lab testing, diet, and lifestyle changes to dramatically improve conception. If you are struggling with infertility... your body is desperately trying to tell you something... focusing on your health will either help you get pregnant naturally or if you do need to go to the fertility clinic it will improve your chances of success. Justine is a Functional Diagnostic Nutrition Practitioner. She was diagnosed with PCOS and struggled with infertility but after taking a functional approach was able to have both her children naturally. In this episode you'll learn: 1) How to make the change from the standard western diet to the healthy fertility diet/lifestyle 2) How to set your intention so you stay committed. These changes may be simple but they are not easy. 3) How to keep it simple without spending hours in the kitchen cooking. 4) What to look for on labels so you don't eat the wrong foods. 5) What to do about emotional eating. How to deal with excuses or lack of motivation 6) Why it's important to include your partner in the changes --- Highlights 5:53 WELCOME JUSTINE ALTMAN 7:07 MY BACKGROUND GROWING UP IN A HEALTHY FOOD HOUSEHOLD As my friend sat and ate her honey sandwich and Chef Boyardee I was like, give me that. 9:27 JUSTINE'S CHILDHOOD EXPERIENCE WITH JUNK FOOD What I thought was making dinner was making a box of Kraft macaroni and cheese or going to pick up McDonald's. 11:17 HOW TO START TRANSITIONING TO A HEALTHY LIFESTYLE How you ease into it is really different from person to personThe most important thing is to eliminate the foods that cause inflammation. Making the mindset shift from “diet' to “lifestyle” Food choices are a gateway to a healthier lifestyle. The surprising ways a healthy lifestyle simplifies your life 15:49 FOCUSING ON YOUR WHY Setting your intention helps you to stay on track Live a healthy lifestyle for yourself and you'll create a ripple effect. 18:49 THE BEST THING YOU COULD EVER DO IS TO START NOW There's always going to be a reason why today or this week or this month isn't the right time. Focus on doing the best you can, not on perfection 20:46 KEEPING IT SIMPLE Start with the healthy foods you're comfortable with and expand from there It's about making upgrades, not forcing yourself to eat things that you hate Allow yourself time for your palate to adjust 23:11 GETTING CONFIDENT ABOUT READING LABELS Being strategic in your grocery shopping What to watch out for on labels Be your own detective with ingredient labels. 26:53 SETTING YOURSELF UP FOR SUCCESS How leftovers help you avoid fast food Why Justine recommends refreshing your pantry before switching to a healthy lifestyle 29:07 BUILDING THE HABIT Be patient with yourself but make a plan and stick with it Give yourself grace through the initial tough period 31:12 EMOTIONAL EATING Looking at your patterns around food and eating Simple strategies you can use to start to shift emotional eating patterns 33:16 KEEP MOVING AND KEEP HYDRATED 34:00 GETTING YOUR PARTNER INVOLVED Doing this together is key. There's really a strong sense of camaraderie --- Resources Excited that our LIVE Fertility Diet Challenge is launching on January 24th. You'll receive newly designed chef-prepared recipes (perfect for winter and curated to optimize fertility). There will be daily motivation, guidance and support from the Fab Fertile Team. Join the Fertility Diet Challenge: https://FertilityDietFreebie.com Fab Fertile Method – https://www.fabfertile.com/what-we-do/ Get Pregnant Naturally | Episode 193: How To Get Pregnant Naturally With Low AMH/High FSH - https://www.fabfertile.com/blog/how-to-get-pregnant-naturally-with-low-amh-high-fsh/ Get Pregnant Naturally | Episode 188: How To Not Waste Time When You Are TTC - https://www.fabfertile.com/blog/how-not-to-waste-time-when-you-are-ttc/ Celiac Disease Foundation | Sources of Gluten https://celiac.org/gluten-free-living/what-is-gluten/sources-of-gluten/ --- Book your Supercharge Your Fertility Discovery call here with your partner During our call, we'll be discussing what you have tried so far and where you've faced challenges. This can feel stressful but is designed to help us get to the root cause of your fertility issues and will help me to give you the best possible action plan at the end of the call. However, to reassure you – on this call we won't be digging into the trauma associated with infertility/miscarriage/loss – rather we are focused on solutions and an ACTION PLAN as to how our Fab Fertile Method can help you get pregnant naturally. --- This episode is sponsored by: Fab Fertile Store Ensure your preconception supplements are free from dyes, filler, and top allergens. Check out our basic recommendations that are essential for preconception health. Visit https://FabFertileStore.com to get your 15% discount. --- Got questions? Join the Fab Fertile Support Group for motivation, support, and education so that you can prepare for pregnancy success. --- Connect with Sarah on social media and learn more about functional fertility solutions that will help you have your baby. Instagram: https://www.instagram.com/fabfertileinc/ Facebook: https://www.facebook.com/sesacoaching/ Twitter: https://twitter.com/fabfertile Linkedin: https://www.linkedin.com/in/sarahclarkfertilitycoach/ --- SHARE: Spread the word! Tell someone else about the show! HELP SUPPORT THE SHOW! Love the show? You'll really love Sarah's resources page - filled with handpicked products/books/devices - get exclusive discounts and support the show by making purchases. Find all our resources here: https://www.fabfertile.com/resources/
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The first time you sit down for a meal at the McDougall Health and Medical Center in Santa Rosa, California, be prepared for a shock. You’ll be surprised at what’s on the table, and what’s not. Dr. McDougall himself explains.
Dermatologist and NPF Scientific Advisory Committee member Dr. Samuel Hwang from the University of California, Davis discusses how diet and lifestyle, including the Western Diet, affects psoriatic inflammation and recent advancements in related research. For disclosures/credit: https://www.eeds.com/em/3524. This program is supported by educational grants from Bristol Myers Squibb, Lilly, Novartis and Ortho Dermatologics.
Sarah Clark & Justine Altman joins us this week to dig into the how-to move from the Standard American/Western Diet to a healthy diet for your fertility. Let's face it eating a diet that is right for our fertility is confusing. Whether it's fertility superfoods, generalized recommendations about what to eat, or avoid for optimized fertility…we may not know where to start. However, we all know that eating packaged processed foods is not healthy for anyone – especially if we are trying to conceive. Changing to a healthy preconception diet is not about deprivation or eating food that tastes like cardboard. It's about finding the most nutrient-dense foods that actually taste good so that you can prepare for a successful pregnancy. And it's not a “diet” – it's a lifestyle change that literally is life-changing – our clients tell us so! You have your WHY, so let's get started. I'm excited to welcome Justine Altman back to the podcast. Justine is part of my team here at Fab Fertile. She is an integral part of our Couples Coaching program - which uses functional lab testing, diet, and lifestyle changes to dramatically improve conception. If you are struggling with infertility...your body is desperately trying to tell you something...focusing on your health will either help you get pregnant naturally or if you do need to go to the fertility clinic it will improve your chances of success. Justine is a Functional Diagnostic Nutrition Practitioner. She was diagnosed with POCS and struggled with infertility but after taking a functional approach was able to have both her children naturally. In this episode you'll learn: 1) How to make the change from the standard western diet to the healthy fertility diet/lifestyle 2) How to set your intention so you stay committed. These changes may be simple but they are not easy. 3) How to keep it simple without spending hours in the kitchen cooking. 4) What to look for on labels so you don't eat the wrong foods. 5) What to do about emotional eating. How to deal with excuses or lack of motivation 6) Why it's important to include your partner in the changes Excited that our LIVE Fertility Diet Challenge is launching on Nov 8th. You'll receive newly designed chef-prepared recipes (perfect for autumn and curated to optimize fertility). There will be daily motivation, guidance, and support from the Fab Fertile Team. Join the Fertility Diet Challenge here>>>>http://fertilitydietfreebie.com/ ---- Book your Supercharge Your Fertility Discovery call here with your partner. During our call, we'll be discussing what you have tried so far and where you've faced challenges. This can feel stressful but is designed to help us get to the root cause of your fertility issues and will help me to give you the best possible action plan at the end of the call. However, to reassure you – on this call we won't be digging into the trauma associated with infertility/miscarriage/loss – rather we are focused on solutions and an ACTION PLAN as to how our Fab Fertile Method can help you get pregnant naturally. ---- TIMESTAMPS: 06:43- INTRO TO TODAY'S TOPIC AND JUSTINE'S BIO 07:54- SARAH'S & JUSTINE'S EATING HISTORY AND BACKGROUND WITH FOOD 12:25- WHERE IS THE BEST PLACE TO START WHEN SHIFTING TO A HEALTHY DIET? Paying attention to what works for you but understanding commitment "We have a decision to make everytime we put food into our mouths." The most important thing is to eliminate foods that cause inflammation The mindset shift that this is not "a diet" and you are not depriving yourself "The food choices become a gateway to a healthier lifestyle." How eating healthier actually simplifies your life (including shopping!) Identifying your "why" (It may be infertility but it will also improve your general health and how you feel) 21:00- DOES IT HURT BINGING JUNK FOOD THE DAY BEFORE YOUR HEALTH JOURNEY BEGINS? "The best thing you can ever do is just start now." "Every forkful you put in your mouth either makes you healthier or sicker." 23:14- KEEPING IT SIMPLE It's a lifestyle change, start where you are What if you don't like certain fruits or vegetables? "It's about baby upgrades." Emotional responses to food and how your palate can change 25:41- WHEN READING LABELS WHAT SHOULD WE LOOK FOR? Being intentional where you go in the grocery store "Be your own detective with the labels." Understanding where Gluten can hide in certain foods 29:38-SETTING YOURSELF UP FOR SUCCESS BY HAVING HEALTHY FOOD AVAILABLE Packing healthy snacks in your purse, cleaning out your pantry Habit changes- and understanding how long they actually take to form 34:12- EMOTIONAL EATING: WHAT CAN WE DO? Understanding your body's cues and what it really wants Other rewards can you give yourself Tips from Sarah about portion sizes 36:23- DRINKING MORE WATER Sometimes we mistake thirst for hunger 37:12-THE IMPORTANCE OF DOING THIS WITH YOUR PARTNER Who is cooking? Are you having to cook separate meals? The importance of your partner "getting it" and being on board 38:57- FINAL THOUGHTS "Just do it as soon as you can." 39:15- DETAILS ABOUT OUR FREE FERTILITY DIET CHALLENGE ---- Use coupon code: getpregnantpodcast to receive 15% discount. Free shipping worldwide. --- Got questions? Join the Fab Fertile Support Group for motivation, support, and education so that you can prepare for pregnancy success. --- Connect with Sarah on social media and learn more about functional fertility solutions that will help you have your baby. Instagram: https://www.instagram.com/fabfertileinc/ Facebook: https://www.facebook.com/sesacoaching/ Twitter: https://twitter.com/fabfertile Linkedin: https://www.linkedin.com/in/sarahclarkfertilitycoach/ ---- LEAVE APPLE PODCAST REVIEW: http://bit.ly/getpregnantreview SHARE: Spread the word! Tell someone else about the show! HELP SUPPORT THE SHOW! Love the show? You'll really love Sarah's resources page - filled with handpicked products/books/devices - get exclusive discounts and support the show by making purchases SHOP here: https://fabfertile.com/resources/ RELATED EPISODES: Fab Fertile Method - https://www.fabfertile.com/what-we-do/ What You Need To Know Before You Decide On IVF - https://www.fabfertile.com/blog/what-you-need-to-know-before-you-decide-on-ivf/ Top Tips To Lose Weight During The Fertility Journey - https://getpregnant.libsyn.com/website/top-tips-to-lose-weight-during-the-fertility-journeyv
Richard Dixon talks about the Alabama Senate filing six anti-vaccine mandate bills, a new study showing that those who are vaccinated spread the Delta variant of COVID at the same rate as the unvaccinated, radio format changes, the Western diet is tied to cognitive decline, Joe Biden's Build Back Better plan failing in Congress, the #BSQotD, and more! See omnystudio.com/listener for privacy information.
For our first episode, we will be diving in to all things blood sugar balance. Balancing blood sugar is at the heart of wellness - no matter who you are or where you are in life, balancing blood sugar benefits you! Blood sugar balance is directly related to improved health, sustained energy, and the prevention of chronic illness.In this episode, you will hear the What, Why and How to balance blood sugar. Before we balance blood sugar, it's important to first note what it means to have elevated blood sugar (1:40).The Western Diet is so popular, but can have a negative impact on your blood sugar. Katy dives in to what exactly the Western Diet is and why it is harmful to health (2:52).Katy shares what it means to balance your blood sugar and why it's important (4:21).The roller coaster effect and what it means for your blood sugar (5:20). There are 5 tips to balancing blood sugar that we can all utilize on a daily basis, that will positively impact blood sugar balance (8:21). Closing remarks (18:00).Connect further with Katy at:IG: @simplyspencer_Website: www.SimplySpencer.com
In 2018, the World Health Organization said the prevalence of a cancer diagnosis reached 18.1 million people – with 9.6 million cancer deaths. Positive lifestyle – such as exercise and diet – reduce the risk to certain forms of cancer. Adherence to a Mediterranean-style eating strategy – higher intake of fruit, vegetables, and whole grains, limited lean meat, fish, and olive oil - reduces the risk to colon and breast cancer.Research is still searching for the optimum plan once an individual is diagnosed with cancer. According to "The Facts About Food After Cancer Diagnosis: A Systematic Review of Prospective Cohort Studies," which appeared in the August 2020 issue of the online, peer reviewed journal Nutrients, “to prevent malnutrition, energy and protein requirements for cancer patients are largely widespread by international guidelines, but little is known about the food choices and dietary regimen a cancer patient should benefit from.”The Italian study researchers point out that, “many ‘cancer diets' are often restrictive, avoiding a whole nutrient class (i.e., meat or dairy products) in the misleading belief that certain foods “feed the tumor.” The Italians sought to determine any possible associations between diet patterns, after a cancer patient's diagnosis, that is affected by a solid tumor, relative to outcomes – mortality, cancer progression, and recurrence.Those study criteria included a meta-analyses (similar studies) that used an adult population over 18 years of age diagnosed with breast, gastrointestinal, gynecological, lung, and urological cancers; post-diagnosis dietary patterns – such as consumption of fruit, vegetables, diary, meat, fish, and cereals; prospective or retrospective cohort studies; over-all survival, all-cause mortality, cancer-specific mortality, death from a non-cancer cause, cancer progression, disease-free survival, cancer recurrence, and recurrence-free survival.The study authors determined that, “the overall results of this systematic review highlight that none of the food categories should be eliminated by cancer patients. Especially, there is no clear association between consumption of meat or animal products and cancer progression/recurrence or CSM (cancer specific survival), after a cancer diagnosis.”However, the Italians also emphasized there was, “a significant positive association between detrimental dietary patterns, such as Western-type Diet (characterized by processed meats, sugar-sweetened soft drinks, and refined grains) and cancer progression.”Note the investigators, “on the contrary, high consumption of fiber, such as whole grain cereals, green and cruciferous vegetables, seem to be protective against cancer progression and mortality.”In conclusion, “detrimental dietary patterns, such as the Western Diet and the high consumption of some food categories (saturated/trans fats, high-fat dairy products) could worsen prognostic outcomes in breast, colorectal and prostate cancer patients. Nevertheless, animal proteins, such as fish, poultry, low-fat dairy products and meat, should not be excluded from cancer patient's diet.”More research is needed relative to a cancer post-diagnostic diet, as it applies to the most common forms of cancer – lung, stomach, gynecological, bladder, and pancreatic cancer.For more information, go to maxwellnutrition.com.
The Chiropractic Forward Podcast: Evidence-based Chiropractic Advocacy
CF 186: Western Diet Hurts and Acupuncture Today we're going to talk about new research based on chronic pain and our regular Western diet. Then we discuss But first, here's that sweet sweet bumper music Purchase Dr. Williams's book, a perfect educational tool and chiropractic research reference for the daily practitioner, from the Amazon store... The post Western Diet Hurts and Acupuncture appeared first on Chiropractic Forward.
Every minute of every day, you and I are getting older. Have you ever wondered what causes your body to age? Well there's been a lot of research into that and there are some very simple things you can do – to slow down that process. Interested? Eat Healthy, Be Healthy You and I have been given such an amazing body, and it's the only body that we'll ever get. It's been wonderfully, exquisitely, uniquely handcrafted and yet so many of us are abusing it into an early grave. All because of what we're putting into our mouths. You are what you eat – literally. Way to many people are contracting diseases that, just a century ago were rare as hens teeth. As we saw last week on the program, cardio-vascular disease was almost unknown in the early 20th century. Today, the World Health Organisation estimates that through heart attack and stroke, cardio-vascular disease kills 16.7 million people every year. That's one third of all deaths worldwide. And please don't think that this is all coming from wealthy countries. Two thirds of those deaths are coming from low and middle-income nations. There's probably not a one of us who doesn't know someone who's had a heart attack or a stroke. Well, if we had been having this discussion back in 1901, almost none of us would have known anyone who'd had a heart attack or a stroke. And yet by 2020, the World Health organisation estimates that there will be around 25 million cardio-vascular disease deaths worldwide. It's on the increase. It's the same with cancer, same with diabetes, same with obesity. People we are eating ourselves into an early grave. And the more research that comes out, the more it all points to the so-called Western Diet. I believe, I know that God gave you and me the most amazing bodies, and the reason we're dedicating a few weeks to talking about this stuff on this program, is because I want to help you avoid becoming a victim of your western diet influences. The thing that sets the western diet apart as we've seen if you've been able to join me, is not it's fat content – there are plenty of instances of traditional diets high in animal fats where the people have a zero rate of cardio-vascular disease, diabetes and obesity – the thing that sets it apart is the high content of processed and refined carbohydrates. Sugar: there's sugar in just about every processed food you buy in the supermarket, white flour, white rice. Sweet drinks, sweet sauces, sweet cereals, sweet just about everything. Last week I shared with you that my top secret for losing 25 kgs (that's 55 lbs) that's a lot of weight, was simply removing refined carbohydrates from my diet. I just want to talk about that a bit more today, because people are shocked. Some think I'm crazy. Others put it down to another fad diet thing. I told someone about it recently, and they said, ‘but aren't you hungry?' We are so conditioned to believe that refined carbohydrates are a normal part of a healthy diet. But they're simply not! If you turn the clock back a century – back to the days when cardio-vascular disease, diabetes, cancer, Alzheimer's disease, obesity and a string of other diseases (which today are pandemics on the increase) were almost completely unknown – the one thing that stands out like a sore thumb, is that refined carbohydrates were a complete rarity in people's diets. People want to know, ‘Well, Berni, if you don't eat bread and cereal and tomato sauce and cakes and biscuits and chips and stuff, what in goodness' name do you eat?' That's the question I'd like to answer for you today, as I sit here with my blood pressure normal, my blood sugar normal, my triglycerides and bad cholesterol low, my good cholesterol high. I wish I could have invited you to dinner last night. It was awesome. My wife Jacqui cooked a roast vegetable salad while I grilled some tandoori chicken on the BBQ. The salad was stunning. She cut up zucchinis, peppers or capsicums, mushrooms, baby tomatoes, onions, beans (I actually can't remember all the veggies that were there) and drizzled them with healthy olive oil and roasted them for half an hour in the oven. Preparation time – about 10 minutes. We then tossed the roasted veggies in a bit of vinegar, added a little salt and pepper and served them up warm with the tandoori chicken that I'd cooked. What was missing was any sauce with sugar in it. What was missing was roast potatoes or white rice or white pasta that would spike your blood sugar level and produce nasty triglycerides in your blood. But do you know, those veggies contained all the carbohydrates my body needs. I had a stack of them too; they tasted exquisite. The meal contained mostly carbs, some protein and some fat – the way a meal is meant to – only the carbohydrates were tucked away inside a whole bunch of natural fibre, which made them slower to digest. Meaning I wouldn't get hungry for a long time, and my blood sugar wouldn't spike. That's how people ate back at the beginning of the 20th century. In fact that's how they've been eating for millennia – plenty of unrefined carbs, unrefined grains which are slow to digest, with plenty of fat – animal fat included and plenty of protein. If we had the courage to turn the clock back 150 years on our diet, to a time when obesity, diabetes and cardio-vascular disease were virtually non existent, what we'd doubtless discover, is that many of the diseases that are the products of the 20th and 21st century western diet would go away. And the exciting thing is that the food is fantastic. My biggest insight? Vegetables rock. Animal fat, rather than increasing my cholesterol levels, actually keeps your blood sugar under control, keeps your appetite under control, and doesn't make you fat. The research is done. The studies are in. And I'm walking proof. There is so much fantastic, natural food out there, and if we were prepared to go for it what we would discover is a whole new food sensation, a healthier body, a body that ages much more slowly, a body that is mentally and physically sharper and far less prone to 20th century diseases. Are you serious about looking after that one body you've been given? Really? So, what are you going to do about it? You are what you eat. Slowing Down the Ageing Process Now that I'm in my mid fifties, I've been doing a lot of reading and research about is the process of ageing. What I've observed is that you can take two people of the same age, and one looks much younger than the other. A smoker will often look much older than a non–smoker of the same age. A person who is significantly overweight will often behave much older as their leg and hip joints struggle with the weight, than a person who is not overweight. I see people who are my age using walking sticks, or hobbling, or finding it hard to get up out of a chair. Is that a random process, or is it something to do with the lifestyle that we lead? Does the process of ageing strike according only to the programming in our DNA, or are there environmental factors that influence ageing? In other words, is there something that you and I can do – in how we live – to slow down the ageing process. That's not a new thought, there's a lot of research going on in this area as our population ages. There are a few different theories of ageing. The most widely accepted one in the medical community is the free radical theory of ageing. You've probably heard of free radicals, but, much like me before I became interested in the ageing process, you haven't paid much attention to them. In a nutshell, the free radical theory of ageing goes like this: Many of the activities of life produce free radicals in our body – these are unstable molecules in search of a spare electron – we won't go too much into the molecular science here, or we'll be at it all day. Heavy exercise produces free radicals. Pollution produces free radicals. And these free radicals are unstable and highly reactive, looking to soak up a free electron from anywhere. Now, every cell in your body needs oxygen to survive – to create energy. Without it, you die. In your cells, energy is produced by tiny structures called mitochondria. It's a complex process, but think of the mitochondria as the power plant in each cell. The process involves free radicals. Most of them are contained, but some of them escape, a bit like some of the muck that comes out of the exhaust of a car. As soon as the free radical escapes, it's out there looking for a spare electron. And when it finds one to grab, the molecule that donated it now becomes an unstable free radical. And those free radicals do all sorts of horrible things in your body if they go unchecked, they create a chain reaction of molecular instability. A researcher in this field Dr Harman puts it this way: It is likely that the life span of an individual is primarily determined by the rate of mitochondria damage, inflicted at an increasing rate with age by free radicals arising in the mitochondria, in the course of normal respiration. Eventually as your mitochondria become less efficient from the accumulate free radicals, a vicious cycle begins. You produce more and more superoxide radicles and have less and less defence against them. Finally your body's various defence mechanisms are overwhelmed. This is exacerbated by very heavy exercise, by smoking, by pollutants and they tell us, by a diet rich in refined carbohydrates. That could explain for instance, why smokers often appear to be much older than their non–smoking peers. But here's the good news: this whole destructive process of free radicals is counteracted by things called antioxidants. Think of the effect of free radicals as the process of oxidising or rusting your body. Anti–oxidants are substances that have free electrons to give away, to stabilise free radicals, to bring your whole system into balance. Where do you get them? From foods rich in antioxidants, namely fruit and vegetables. In fact the brighter the colour of the fruit or vegetable, mostly the richer they are in antioxidants. Broccoli, spinach, berries, red and green and yellow capsicums or peppers, the brighter the better. An antioxidant is simply a substance that quenches a free radical by donating an electron, thereby ending the free radical chain of events that destroys mitochondria, and causes the body to age, and eventually to die. There's a very, very, very good reason why they keep telling us to eat lots of vegetables and fruits – because they're healthy for us and – this is how they contribute to our health (as well as the vita nutrients that they pump into our bodies). Contrast that with a diet high in refined carbohydrates which creates an over supply of insulin – hyperinsulinism it's called – to deal with all the sugars you're pumping into your body. And as one researcher put it, hyperinsulinism puts you in the ageing express lane. Agree with him or not, Dr Robert Atkins puts the whole thing in perspective as he writes this about the historical context of our diets: No human civilisation ever, has consumed a preponderance of carbohydrates in the form of refined products with most of their original vita-nutrient content discarded, until the 20th century westernised diet became prevalent. Eat your fruit and veggies – which by the way are stunning – and ditch the refined carbohydrates, and in one fell swoop you're introducing the antioxidants you need to slow the ageing process, and removing the greatest single cause of putting people into the ageing fast lane. That's it in a nutshell. God has a mighty plan for your life, but that plan can't and won't be fulfilled if you prematurely destroy the precious body that He's given you. Listen again to the Apostle Paul and what he says about this body you've been given: Or do you not know that your body is a temple of the Holy Spirit within you, whom you have from God? You are not your own, for you were bought with a price. So glorify God in your body. (1 Corinthians 6:19-20) And what we've been talking about, actually, is exactly what our parents told us around the table – eat your vegetables. It ain't rocket science, is it? The Impact of Exercise Now if you were able to join me last week, you'll know that in this whole healthy living series, we had a bit of a chat about exercise. But if you heard that message, don't tune out, because we're going to circle back and pick up something important that could change your life. I know that there are some people listening today who don't have easy access to motorised transport but way too many people are living a sedentary existence. Sitting in front of computer screens all day –rarely walking anywhere, let alone working up a sweat. I'm like that and so, for much of my adult life, I did almost no exercise whatsoever. And the less exercise you do, the less you want to do. Deep down, I knew that my sedentary life style wasn't exactly making me healthy. When you added to that a diet high in refined carbohydrates, sugars and the like, I was heading for diabetes and cardio-vascular disease. I was an absolute Monty for a heart attack or stroke. My father died of complications related to Type II Diabetes – and it seemed that I was walking in his footsteps. Did you know that single biggest statistical indicator of an impending heart attack isn't your blood triglyceride or cholesterol levels – it's a lack of exercise. Inactive men for instance have nearly four times the risk of developing diabetes compared with just moderately physically active men. Active lifestyle by the way is also linked with significantly reduced cancer risk. And exercise is the key factor – THE KEY FACTOR – in preventing disability as you age. People who exercise regularly have a substantially lower risk of becoming disabled later in life. In fact the research clearly demonstrates that disability is not an inevitable part of aging. It can easily be defied by moderate physical activity, starting … now! It's also a key overall factor in your longevity of life. Are you getting the picture here? Am I making you feel uncomfortable by being that direct about all of this? Oh good. That's what's meant to be happening, if you're one of the people who is where I used to be. I want it to sink in that you are cruising towards a certain early demise – if not immediate death, then an unhealthy, uncomfortable life. Now so far in this series I've talked a lot about dietary choices and the impact of those choices on our health, our wellbeing and our lifespans. But now I want to tell you some things that are going to get you motivated to start introducing deliberate exercise into your routine. Three simple things to get you moving off your backside. Here's the first one: Some exercise is better than no exercise. Let me say it again, some exercise is better than no exercise. And you would be surprised at how low a level of exercise starts to reduce your risks around cardiovascular disease and diabetes. Are you ready? A brisk walk for a half-an-hour at least three times a week will significantly improve your health outcomes. Every day or most days is better. But just three half-hour walks at whatever constitutes a brisk pace for you, is all it takes. I know, I know – you don't have time right? You have a long commute. You have kids to worry about. You work long hours. I know all of the excuses cause I used to use them all. Remember to tell them all to your cardiologist when you're lying on the stretcher in the emergency ward, trying to live through your heart attack would you? At some point we all need to come to grips with how utterly ridiculous the “I don't have time” excuse really is. If you don't have time to exercise, then you'd better get your affairs in order, because you'll be making time to be sick … or dead. Here's the second simple thing that is going to get you moving – learn to exercise your options. We don't all like the same thing. I absolutely love walking. You may not. Okay then, choose something that you do enjoy. Some people love to get on a treadmill and watch TV or listen to music or a podcast. A guy I used to work with Ron, he's retired now, he loved swimming in the mornings and now, in his mid seventies, owns a sheep farm and is a fit as a fiddle. There are so many options and most of them are free. Just pick one – the one you like, the one you enjoy – and do some moderate levels of exercise. There is never a time where I am telling you to become a marathon runner. In fact, there's a lot of evidence that very heavy exercise creates lots of free radicals, reduces your immune response, and can impact severely on your bones and joints, particularly as you get older. Moderate exercise at a brisk pace, three, four or five times a week for a half-an-hour is all we're talking about. And here's the third great bit of news: when you exercise moderately you're going to change your dietary choices almost automatically. Why? There's a simple psychology that when you invest the time and energy in a bit of exercise, you're not going to want to undo it all by shoving a packet of crisps or a bar of chocolate down your gullet. And really, I found that the positive reinforcement of moderate exercise really helped me change my dietary behaviour that contributed significantly to weight loss. Doesn't matter what age you're at, what fitness level you're at, it is never too late so start with some moderate exercise. And the wonderful thing about the amazing body that your God has given you is that it will guide you as to what is the right level of exercise. Starting off with something that works for you is absolutely the right thing to do – and little by little, as your fitness levels improve and your dietary levels change, you end up feeling so much better. Yesterday afternoon I went down to the local gym that I'm a member of (which is in itself a miracle) and ran and walked 6 km in 45 minutes, worked up a sweat, pumped some iron, and came out feeling fantastic. That is such a long way from the days when I was grossly overweight … it all started with the first step. Remember – some exercise is better than no exercise. And your life depends on it.
Tim continues with his series exploring food ingredients! Mainly the ones that are most harmful to your health! In this episode Tim talks VEGETABLE OILS and how, sadly, they are a major part of the Western Diet. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/twt-nextlevelhealth/message Support this podcast: https://anchor.fm/twt-nextlevelhealth/support
Previous episodes have all been looking at nutrition strategies and foods to INCLUDE to improve brain performance. This week, Casey discusses what foods to AVOID to prevent cognitive impairments. Give this week a listen to make sure you aren't inadvertently including foods that are getting in your way!If you enjoy this series and have found any value from it, please share it with a friend. My goal is to cut through the crap and spread some credible nutrition information! And if you have any other feedback, or would just like to say 'Hello', my email is caseythomasrd@gmail.com. I read everything you guys send me!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Hoy hablaremos sobre qué es la Dieta Occidental o Western Diet, ni más ni menos que el tipo de dieta que sigue más del 80% de la población general en el Mundo Occidental. Además, comentaremos qué tipo de enfermedades puede provocar este tipo de dieta basada en ultraprocesados a largo plazo. Como es costumbre, os añado algunos artículos al respecto: La Dieta Occidental y la demencia, la inflamación y el cáncer: https://www.elespanol.com/cocinillas/recetas/saludables/20180121/cancer-diabetes-demencia-riesgos-dieta-occidental/1001115938396_30.html La Dieta Occidental y la inflamación intestinal: https://www.elespanol.com/ciencia/nutricion/20200509/cuatro-alimentos-habituales-inflaman-intestino-sin-que-te-des-cuenta/488201955_0.html https://www.elespanol.com/ciencia/nutricion/20200721/componentes-habituales-dieta-inflaman-intestino/506199531_0.html El exceso de grasas de la Dieta Occidental y el riesgo de infarto: https://www.elespanol.com/ciencia/nutricion/20210308/destruye-corazon-provoca-inflamacion-dieta-comun-espana/562944004_0.html Podéis encontrarme en (¡OJO! ¡Nueva cuenta de Instagram!): Facebook: https://www.facebook.com/medciencia Twitter: https://twitter.com/MedCiencia Instagram: https://www.instagram.com/drrobertomendez/ Hoy hablaremos sobre qué es la Dieta Occidental o Western Diet, ni más ni menos que el tipo de dieta que sigue más del 80% de la población general en el Mundo Occidental. Además, comentaremos qué tipo de enfermedades puede provocar este tipo de dieta basada en ultraprocesados a largo plazo. Como es costumbre, os añado algunos artículos al respecto: La Dieta Occidental y la demencia, la inflamación y el cáncer: https://www.elespanol.com/cocinillas/recetas/saludables/20180121/cancer-diabetes-demencia-riesgos-dieta-occidental/1001115938396_30.html La Dieta Occidental y la inflamación intestinal: https://www.elespanol.com/ciencia/nutricion/20200509/cuatro-alimentos-habituales-inflaman-intestino-sin-que-te-des-cuenta/488201955_0.html https://www.elespanol.com/ciencia/nutricion/20200721/componentes-habituales-dieta-inflaman-intestino/506199531_0.html El exceso de grasas de la Dieta Occidental y el riesgo de infarto: https://www.elespanol.com/ciencia/nutricion/20210308/destruye-corazon-provoca-inflamacion-dieta-comun-espana/562944004_0.html Podéis encontrarme en (¡OJO! ¡Nueva cuenta de Instagram!): Facebook: https://www.facebook.com/medciencia Twitter: https://twitter.com/MedCiencia Instagram: https://www.instagram.com/drrobertomendez/
The dietary pattern that characterizes the Western diet is strongly associated with obesity and related metabolic diseases, but biological mechanisms supporting these associations remain largely unknown. We argue that the Western diet promotes inflammation that arises from both structural and behavioral changes in the resident microbiome. The environment created in the gut by ultra-processed foods, a hallmark of the Western diet, is an evolutionarily unique selection ground for microbes that can promote diverse forms of inflammatory disease. Recognizing the importance of the microbiome in the development of diet-related disease has implications for future research, public dietary advice as well as food production practices. Research into food patterns suggests that whole foods are a common denominator of diets associated with a low level of diet-related disease. Hence, by studying how ultra-processing changes the properties of whole foods and how these foods affect the gut microbiome, more useful dietary guidelines can be made. Innovations in food production should be focusing on enabling health in the super-organism of man and microbe, and stronger regulation of potentially hazardous components of food products is warranted. Ultra-Processed Foods as Drivers of Diet-Related Disease Factors that Promote Inflammation through Diet-Microbiome-Host Interactions Acellular Nutrients—A Major Shift in Our Diets Food Additives Solutions Probiotic or fermented foods could contain beneficial bacterial molecules left in the foods during fermentation. Studies have shown beneficial effects of fermented milk products on metabolic markers in mice [74,75,76], also independently of the presence of live probiotic bacteria, either in the product or in the gut of the recipient [77]. It has been demonstrated in vitro that metabolites from probiotic bacteria are capable of reducing the release of pro-inflammatory cytokines A large body of research now supports the hypothesis that the Western Diet is causing changes in gut microbiota associated with obesity and metabolic disease [67]. There also seems to be consensus that fixing the diet-induced dysbiosis is a possible approach in fighting the obesity epidemic [108]. Several researchers speak of the promising potential of gut microbiota-modifying therapies, such as probiotics, prebiotics, synbiotics or fecal microbiota transplants and the need for more research into these topics
Justine Altman joins us today as we’re digging into how to move from the Standard American/Western Diet to a healthy diet for your fertility. Let’s face it eating a diet that is right for our fertility is confusing. Whether it’s fertility superfoods, generalized recommendations about what to eat or avoid for optimized fertility…we may not know where to start. However, we all know that eating packaged processed foods is not healthy for anyone – especially if we are trying to conceive. Changing to a healthy preconception diet is not about deprivation or eating food that tastes like cardboard. It’s about finding the most nutrient-dense foods that actually taste good so that you can prepare for a successful pregnancy. And it’s not a “diet” – it’s a lifestyle change that literally is life-changing – our clients tell us so! You have your WHY, so let’s get started. I'm excited to welcome Justine Altman back to the podcast. Justine is part of my team here at Fab Fertile. She is an integral part of our Couples Coaching program - which uses functional lab testing, diet, and lifestyle changes to dramatically improve conception. If you are struggling with infertility...your body is desperately trying to tell you something...focusing on your health will either help you get pregnant naturally or if you do need to go to the fertility clinic it will improve your chances of success. Justine is a Functional Diagnostic Nutrition Practitioner. She was diagnosed with POCS and struggled with infertility but after taking a functional approach was able to have both her children naturally. In this episode you'll learn: 1) How to make the change from the standard western diet to the healthy fertility diet/lifestyle 2) How to set your intention so you stay committed. These changes may be simple but they are not easy. 3) How to keep it simple without spending hours in the kitchen cooking. 4) What to look for on labels so you don’t eat the wrong foods. 5) What to do about emotional eating. How to deal with excuses or lack of motivation 6) Why it’s important to include your partner in the changes Excited that our LIVE Fertility Diet Challenge is launching on April 19th. You'll receive newly designed chef-prepared recipes (perfect for spring and curated to optimize fertility). There will be daily motivation, guidance, and support from the Fab Fertile Team. Join the Fertility Diet Challenge here>>>>http://fertilitydietfreebie.com/ TIMESTAMPS: 06:45- INTRO TO TODAY'S TOPIC AND JUSTINE'S BIO 07:48- SARAH'S & JUSTINE’S EATING HISTORY AND BACKGROUND WITH FOOD 12:27- WHERE IS THE BEST PLACE TO START WHEN SHIFTING TO A HEALTHY DIET? Paying attention to what works for you but understanding commitment "We have a decision to make every time we put food into our mouths." The most important thing is to eliminate foods that cause inflammation The mindset shift that this is not "a diet" and you are not depriving yourself "The food choices become a gateway to a healthier lifestyle." How eating healthier actually simplify your life (including shopping!) Identifying your "why" (It may be infertility but it will also improve your general health and how you feel) 21:04- DOES IT HURT BINGING JUNK FOOD THE DAY BEFORE YOUR HEALTH JOURNEY BEGINS? "The best thing you can ever do is just start now." "Every forkful you put in your mouth either makes you healthier or sicker." 23:18- KEEPING IT SIMPLE It's a lifestyle change, start where you are What if you don't like certain fruits or vegetables? "It's about baby upgrades." Emotional responses to food and how your palate can change 25:45- WHEN READING LABELS WHAT SHOULD WE LOOK FOR? Being intentional where you go in the grocery store "Be your own detective with the labels." Understanding where Gluten can hide in certain foods 29:43-SETTING YOURSELF UP FOR SUCCESS BY HAVING HEALTHY FOOD AVAILABLE Packing healthy snacks in your purse, cleaning out your pantry Habit changes- and understanding how long they actually take to form 34:17- EMOTIONAL EATING: WHAT CAN WE DO? Understanding your body's cues and what it really wants Other rewards can you give yourself Tips from Sarah about portion sizes 36:29- DRINKING MORE WATER Sometimes we mistake thirst for hunger 37:19-THE IMPORTANCE OF DOING THIS WITH YOUR PARTNER Who is cooking? Are you having to cook separate meals? The importance of your partner "getting it" and being on board 39:03- FINAL THOUGHTS "Just do it as soon as you can." 39:22- DETAILS ABOUT OUR FREE FERTILITY DIET CHALLENGE --- Book your Free Supercharge Your Fertility Discovery Call here: https://intakeq.com/booking/cZ7XW6 --- Sponsored by: BLUBlox (Sleep+ is the world’s most advanced blue and green light blocking glasses addressing the exact frequencies of light required after dark to optimally produce melatonin for restorative sleep and health) Visit BLUBlox website at: http://bit.ly/BLUBlox Use coupon code: getpregnantpodcast to receive 15% discount. Free shipping worldwide. --- Got questions? Join the Fab Fertile Support Group for motivation, support and education so that you can prepare for pregnancy success. --- Connect with Sarah on social media and learn more about functional fertility solutions that will help you have your baby. Instagram: https://www.instagram.com/fabfertile/ Facebook: https://www.facebook.com/sesacoaching/ Twitter: https://twitter.com/fabfertile Linkedin: https://www.linkedin.com/in/sarahclarkfertilitycoach/ Related Episodes: Functional Medicine 101 - https://www.fabfertile.com/blog/functional-medicine-101-and-your-fertility/ How Not To Waste Time When You Are TTC: https://www.fabfertile.com/blog/how-not-to-waste-time-when-you-are-ttc/ What You Need To Know About The Elimination Diet if You Are TTC: https://www.fabfertile.com/blog/what-you-need-to-know-about-the-elimination-diet-if-you-are-ttc/
If you are on a typical "Western Diet", there are supplements you need to supplement certain vitamins and minerals your body needs but doesn't get through food.Taken from Episode 1: What is Immunity?: https://youtu.be/T4tQ30CDiZUFollow us @dietizers on Twitter, Facebook, LinkedIn, and Pinterest#WesternDiet #Supplements #TheImmunityPodcast
Tell me what your diet’s like and I can tell you where your health is headed. One of the largest determinants of health is what you put in your mouth day after day, year after year. It’s more predictive than genetics, and it’s something you can control. Today I will talk to you about the Western Diet, it’s catastrophic health impacts, how it compares to the ancestral, Paleolithic diet, and what you can do to change your future by changing your diet. Resources talked about in this episode Blog mentioned - Food Matters Blog mentioned - Dr. Neustadt’s 3 Steps to Eating Healthy For Life Blog mentioned - Change Your Biochemistry to Change Your Health Blog mentioned - How to Choose the Right Blog mentioned - Cooking Oil
Help, I’m pre-diabetic! The Kurang Manis Sugar, Less Podcast
In this 3rd episode of The Kurang Manis Podcast, we meet Dr. Pran Yoganathan, a gastroenterologist and hepatologist based in Sydney. A passionate educator, a Mathematician-turned doctor who has lived in Sri Lanka, Africa, New Zealand and Australia, Dr. Pran wants to put the power in his patients' hands and provide them with data so that they can embark on their own journeys of self-healing using the philosophy of “let food be thy medicine”. Harnessing creative technology and 14,400 followers on Instagram @dr_pran_yoganathan, he stresses that his educational memes are not medical advice or recommendations, simply his opinions -- and rather strong science-backed opinions they are too! Find out why Dr. Pran's diet of choice - grass-fed steak and eggs has raised eyebrows and temperatures not just in the oven, but in conversation with peers as well. Ask him about butyrate and you'll get him all fired up and excited! Now, are WE ready to absorb the fact that we're meant to burn fat for energy and not glycogen? Let's save that for perhaps another episode. Joining co-hosts Jasmine Low and Nikki Yeo in this same episode are Dr. Desmond Menon, medical lab scientist featured in Ep. 2 Do Our Genes Predispose us to Diseases of our Parents and Malaysia's "biggest" stand-up comedian Papi Zak. ******* More about Dr. Pran Yoganathan ******* Graduating from medicine from the University of Otago in New Zealand, Dr. Pran is a Fellow of the Royal Australian College of Physician (FRACP) and a member of Gastroenterological Society of Australia (GESA). He has accredited expertise in Upper Gastrointestinal Endoscopy and Colonoscopy as certified by the Conjoint Committee for the recognition of training in Gastrointestinal Endoscopy. Dr. Pran works in the public and private sectors in Greater Sydney and has a strong interest in the field of human nutrition. He practices an approach to healthcare that assesses the lifestyle of the patient to see how it impacts on their gastrointestinal and metabolic health. Dr. Pran believes that the current day nutritional guidelines may not be based on perfect evidence and he passionately strives to provide the most up to date literature in healthcare and science to provide “Evidence-Based Medicine”. He is a strong motivator and aims to empower his patients to embark on a journey of self-healing using the philosophy of “let food be thy medicine”. Dr. Pran has a special interest in conditions such as Gastro-oesophageal Reflux (GORD), Irritable Bowel Syndrome (IBS) and abdominal bloating. He takes a very thorough approach to resolve these issues using dietary manipulation In conjunction with an accredited highly qualified dietician rather than resort to long-term medications. ******* We hope you've enjoyed these bite-sized pieces of information. Read the full article: https://www.asiafitnesstoday.com/?p=9233 ⚫️
Multimedia Editor of Thorax, Rachael Moses, interviews Dr Sonali Bose, Faculty in the Division of Pulmonary, Critical Care Medicine and Sleep Medicine, New York. They discuss the relationship between western diet, particularly increased advanced glycation end product and meat consumption, in childhood wheeze and the public health implications of the findings. Read the related articles: https://thorax.bmj.com/content/early/2020/11/22/thoraxjnl-2020-216109 https://thorax.bmj.com/content/early/2020/11/25/thoraxjnl-2020-216369
The first time you sit down for a meal at the McDougall Health and Medical Center in Santa Rosa, California, be prepared for a shock. You’ll be surprised at what’s on the table, and what’s not. Dr. McDougall himself explains.
In this episode Mat has a fascinating discussion with Michael S. Fenster MD about the realities of the modern Western diet as it pertains to human health. Mike; known to friends and fans simply as “Chef Dr. Mike,” is America's only board-certified interventional cardiologist and professional chef and in this energised exchange they covered a broad spectrum of highly digestible (pun intended) 'latest-greatest' medical science topics that any open minded human would appreciate to hear. So if you want to know more about the how the modern Western diet is to blame for so many lifestyle diseases and what steps we can take to reverse or prevent them, plug in your ear-buds and give this a listen. As an aside, Mike currently writes a regular column for Psychology Today and has authored several books including The Fallacy of The Calorie: Why The Modern Western Diet is Killing Us and How to Stop It (Koehler Books, 2014), Ancient Eats: The Greeks and Vikings (Koehler Books, 2016) and Food Shaman: The Art of Quantum Food (Post Hill Press, June 2018) is his latest offering. Resources: Twitter @ChefDrMike Facebook https://www.facebook.com/chefdrmike Instagram realchefdrmike Website www.chefdrmike.com. He can be reached at info@chefdrmike.com Additional resources and links: Psychology Today column Videos/Appearances Link to Books Radio show archives Journeys into Quantum Food podcast link on iTunes
Hey Eavesdroppers, this week we are joined by globetrotting blogger, photographer and podcaster, Gary Arndt from https://everything-everywhere.com/ Gary was a great guest with knowledge of all sorts of different subjects that we touched on during the conversation. Thanks to Gary for sparing some of his time to spend with us, were sure you'll find it as interesting as we did. Please check out Gary's website https://everything-everywhere.com/ You can find his podcast Everything Everywhere Daily on your favourite podcast platform. Also, lots of Gary's photography is on display at his Instagram profile https://www.instagram.com/everythingeverywhere/?hl=en Topics covered with Gary...Island Hopping, Leaving the Rat Race, Commuting, Capital Cities, New Yorkers, Local Knowledge, British Currency, Origins of Football, Mayan Ruins, Tourism, Civil War Pensioners, English Longbow, Eurasian Steppe Horse Archers, Genghis Khan, Church of The Holy Sepulchre, Jordan, The Dead Sea, Sea-level Rise, Marine Archaeology, Graham Hancock, Universal Flood Myths, Continental Drift, Plate Tectonics, Uniformitarianism, Randall Carlson, Ice Age Termination, Ancient Migration, Vikings, Dawn of Agriculture, Modern Western Diet, Refined Carbohydrates, Weight Loss, Overkill Hypothesis, Ancient Handbags, Axum, Ark of the Covenant, Lighthouse of Alexandria, Recycled Architecture and The Carnivore Diet.... We went a little long during the post-match debrief, Bank Holiday weekend and all, we sorted some Housekeeping and went over some of the latest Covid developments, chaos in the US and other silly stuff in the usual way. Producer Credits for episode 147: Anne Lulunny, Adam and Serfiel, C.A.Alexa, Chad Rickman, VeraLynn, Gav Scott, Full Metal Keto AF and Anonymous. Message us here....follow, like, subscribe and share. (comments, corrections, future topics etc). We read out iTunes reviews if you leave them. theamishinquisition@gmail.com https://twitter.com/amishinqpodcast https://www.facebook.com/amish.inquisit.3 https://www.instagram.com/theamishinquisition/?hl=en https://www.youtube.com/channel/UCmv8ucrv5a2KpaRWyBWfBUA Find out how to become a Producer here... http://www.theamishinquisition.com/p/phil-1523918247/ The Amish Inquisition is 100% supported by YOU. NO Ads, NO Sponsorship, NO Paywalls. We really don't want to suckle at the teat of some faceless corporate overlord. But that is only avoidable with your help! Join your fellow producers by donating to The Amish Inquisition via the PayPal button on our website, simply donate whatever you think the show is worth to you. If you find the podcast valuable, please consider returning some value to us and help keep the show free and honest.
In this episode, the host Angie Gust, talks about the important role of nutrition in susceptibility to the coronavirus. A recent article reported that the Western Diet activates the innate immune system and impairs adaptive immunity. This then leads to inflammation and causes your body to have weakened defenses against viruses like the coronavirus. It is so important to, if you don’t already eat healthy foods, to make it a top priority. Turning to the environment, in July, presidential nominee, Joe Biden, came out with his Unity Task Force recommendations which will make historic investments in a green economy. References Andrew, S. July 21, 2020. Greta Thunberg will donate $114,000 to fight the coronavirus in the Brazilian Amazon. CNN. https://www.cnn.com/2020/07/21/world/greta-thunberg-donate-covid-amazon-trnd/index.html Bradner, E. and Mucha, S. July 14, 2020. Biden proposes $2 trillion for clean energy projects, calls for end to power plant emissions by 2035. https://www.cnn.com/2020/07/14/politics/joe-biden-clean-energy-plan/index.html Butler, MJ, Barrientos, RM. 2020. The impact of nutrition on COVID-19 susceptibility and long-term consequences. 87:53-54.doi: 10.1016/j.bbi.2020.04.040. Epub 2020 Apr 18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165103/ CDC. COVID 19. Considerations for schools. https://www.cdc.gov/coronavirus/2019-ncov/community/schools-childcare/schools.html Obama White House. Fact Sheet: The Economic Challenge Posed by Declining Pollinator Populations Jun 20, 2014 Obama White House. https://obamawhitehouse.archives.gov/the-press-office/2014/06/20/fact-sheet-economic-challenge-posed-declining-pollinator-populationsr
Call me at 888-283-7272 Send me a DM on instagram @AsaRxTV I will answer these daily and tweet the answers @AsaRxTV with the hashtag #AsaRxExperience How Fast Can You Live Your Potential and Be Healthy? You don't have to live lower than your potential for the rest of your life! Take the Asa Rx Healthy Solution Quiz by answering simple questions and our Healthy Solution will show you how quickly you can reach your healthy goals! Our Gift To You As a complimentary gift to you Asa wants to give you a copy of his international best-selling book to help you GET STARTED for FREE . Living Healthy is often misunderstood and overcomplicated. It doesn't have to be! We made it simple. After just 30 days of following Healthy University, 9 out of 10 users feel more confident in their choices toward a healthy future. Get Healthy University. Give us 2 minutes a day and Asa will change your life! Get the training that you need. How does your daily healthy lifestyle choices stack up? Our Healthy University will show you what you need (and don't need), which questions to ask, and how to make the best natural lifestyle choices. In over 500 videos learn the best tools and strategies to get healthy and stay healthy from any device and on your time. Just 2 minutes a day! Find the Right Healthy Provider. Finding the right healthy provider doesn't have to be complicated. Our free conversation with our healthy provider specialists makes it easy to know what questions to ask so you can make a confident choice. Meet with a provider on us! Listen and Watch Anytime, Anywhere. The Asa Rx app lets you download episodes for offline playback, customize your content, and see what's coming up!
Ökotrophologe Prof. Dr. Ritter über Food-Trends, Western Diet, Essen als sozialem Kit, nachhaltige Ernährung, Insekten als Nahrung der Zukunft u.v.m. Ihr findet weitere Infos zu Prof. Ritter und seinen eigenen Podcast "Klausurrelevant" auf der Homepage der FH Münster sowie seinen TED Talk auf YouTube: https://www.fh-muenster.de/oecotrophologie-facility-management/professoren/guido-ritter.php ; https://www.youtube.com/watch?v=V6QaEgdEgyk ; https://www.fh-muenster.de/oecotrophologie-facility-management/aktuelles/klausurrelevant-podcast.php
In this episode we have our Wellness Director and super hero, Pamela, joining us to chime in on weight loss and gut health! In our Western diet and way of life, how does this affect, not only our weight loss, but our body form the inside and out.
I do a review/summary on all episodes 1-10! I translate English episodes to Japanese and Japanese episodes to English, covering key points of the discussion and also sharing what I learned from those interviews. Also planning on having a video for this! Timeline 2:42 EP.1 Sae Kyo 11:35 EP.3 Masahito Yamamoto 11.55 EP.5 Tomohito Oshiro 27:17 EP.7 Koji Yashiki 34:40 EP.9 Ayano Shiba Social Media Account Sae Kyo Sae's YouTube:さえタイム/ sae kyo Twitter: _saekyo_ Instagram: smiley_19.95 Tomohito OSHIRO Instagram: @enema098 Twitter: @gws581 Koji Yashiki Twitter: kj_moment References Hypothalamic Amenorrhea and the Long-Term Health Consequences https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374026/ JSCO2016: International Session 2 Colorectal Cancer http://www.jsco.or.jp/english/index/page/id/202 The mysteries of type 2 diabetes in developing countries https://www.who.int/bulletin/volumes/94/4/16-030416/en/ The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532387/ Coronavirus: Does being overweight or obese affect how ill people get? https://www.bbc.com/news/health-52561757 Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta‐analysis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596401/ What is Alzheimer's Disease https://www.alz.org/alzheimers-dementia/what-is-alzheimers CLINICAL STAGES OF ALZHEIMER'S https://www.alzinfo.org/understand-alzheimers/clinical-stages-of-alzheimers/ Effects of exercise on brain function: role of free radicals https://pdfs.semanticscholar.org/d205/385f65afabec64c77e9fe4984025ddeb96ac.pdf
[06:00] The Western Diet (8 minutes) How many diseases today are a result of an unhealthy diet? There are billion-dollar industries set up to address the effects of these bad habits, but how many resources are put toward addressing the cause of sickness? [14:00] What Can You Do? (23 minutes) Did God create humans to get sick? Does it make sense that God would create humans to be vulnerable to infectious disease? There is a cause for sickness and disease! [37:00] God’s Health-Care System (38 minutes) This world’s health-care systems primarily address the effect of bad habits and unhealthy lifestyles. Today, in the midst of the coronavirus panic, the experts are telling people to stay inside, away from fresh air and sunshine. The irony is that keeping people indoors makes them more vulnerable to the disease! In a perfect world, what should the response to diseases like coronavirus be?
This solo episode is all about the foods to eat for your skin to be at its best! While we all love a good mud mask or retinol serum, products are never the final answer to achieving healthy, supple skin. Tune in to hear about the dietary dos and don’ts that will keep your skin looking its best for years to come! Links to Products/Resources Mentioned: STUDIES: Acne-Free Population, Western Diet & Acne, Green Tea & Skin, Impact of Sugar on Skin, Benefit of Avocados, Best Foods For SkinPRODUCTS: Magic Bullet BlenderFor some of my favorite supplements that achieve healthy, glowing skin, please check out the Naked Beauty Amazon ShopJoin the Naked Beauty Community on IG: @nakedbeautyplanet Check Out All Episodes On: https://www.nakedbeautypodcast.com/Rate, Subscribe & Review the Podcast on Apple Thanks for all the love and support. Tag me while you’re listening @nakedbeautyplanet & as always love to hear your thoughts :) Stay in touch with me: @brookedevard See acast.com/privacy for privacy and opt-out information.
On this week’s edition of Weekend Ag Matters: Valent USA talks about their Perpetuo herbicide which is new for 2020; BASF talks about Operation Weed Eradication; and Ken Root talks about the expansion of the Western Diet.
Dr. James Raniolo describes the unseen impact on our hormones the Western diet, plastics in the environment, and various chemical compounds have and how they affect the balance of estrogen and testosterone levels in our bodies without our knowledge.Learn More About Dr. James Raniolohttps://themedicinewheel.org/dr-james-raniolo/Please rate our podcast and subscribe to say in the loop.Subscribe to our podcast:Apple:https://apple.co/34x71OqSpotify: https://spoti.fi/2CivYRGLearn More:https://themedicinewheel.org/Subscribe to our YouTube Channel:http://bit.ly/2rdMIqSLike us on Facebook:https://www.facebook.com/themedwheelFollow us on Twitter:https://twitter.com/themedwheelFollow us on Instagram:https://www.instagram.com/themedwheel/DISCLAIMERhttps://themedicinewheel.org/disclaimer/The information shared in this podcast is for general information only and should not be construed as medical advice and understand that no doctor-patient relationship is formed. The use of this information and educational materials link to this podcast and website are employed at the user's own risk.Support the show (http://www.themedicinewheel.org/omcare/)
Die Aufnahme von Lebensmitteln ist lebensnotwendig. Doch stellt sich die Frage, ob unsere „Western Diet“ mit industriell gefertigten und stark verarbeiteten Nahrungsmitteln uns tatsächlich guttut.
Tuesday night, Erik will discuss a variety of diets along with their pros and cons. There are so many diets out there, but which one is best for you? The Keto diet? The Paleo Diet? The South Beach Diet? The Atkins Diet? A vegetarian diet? A pescatarian diet? A vegan diet? A low calorie diet? An omnivore diet? A carnivore diet? The Mediterranean Diet? The Weight Watchers Diet? Or something else like the Zone Diet, a raw food diet, The Western Diet, etc.? So many choices, so little time! After 20-30 minutes of discussion, Erik will answer questions from callers channeled by Michelle. THE CALL IN NUMBER HAS CHANGED. IT IS NOW: 646-716-9735. You can find out more about Michelle by thehealingh-art.com.
Special thank you to Liane Abe and Valarie Hummel who are the newest patrons of the Podcast. In this weeks conversation, I sat down with Registered Dietician, PhD researcher and Twitter “Equal Opportunity Nutrition Critic” Jake Mey. I wanted to speak to Jake because he seemed to have unique philosophies on areas that are particularly hot right now. He conducts research on skeletal muscle metabolism, ketones and carbohydrates. He is not wedded to one particular dietary strategy vs. another which provided a nuanced and educational back and forth on various nutrition topics. We speak about the concept of moderation in a world that is becoming more and more unhealthy and answer the perennial question “Can I eat Pop-Tarts and still be healthy?” We also speak about ketones, ketosis and the pros and cons for lay people and athletes. And we end with Jake's perspective on the nutrition conversations that are happening right now on social media and if he thinks these are productive, wastes of time or somewhere in between. If you are active on Twitter, I would recommend following him @CakeNutrition, and yes, we speak about the origins of that handle, too. I know you'll enjoy this conversation with the knowledgeable and jovial Dr. Jake Mey.
The Staying Young Show 2.0 - Entertaining | Educational | Health & Wellness
Have you or a loved one had sepsis? This is Judy Gaman and this is your Stay Young Medical Minute. Sepsis is one of the leading causes of death in the US and occurs when organs and tissues are damaged by the body's immune response. In fact, 1 in 3 deaths in a hospital are due to sepsis. New research out of Portland State University suggests that diet may play a large role in developing the infection and it doesn't look good for America. The western diet increases risk and severity of developing sepsis. Swap out your processed foods for fresh ones and add some exercise into your daily routine. Talk to your doctor if you have questions about your diet. This Stay Young Medical Minute is brought to you by Executive Medicine of Texas, a leader in preventative and proactive medicine. Learn why patients from around the globe trust Executive Medicine of Texas to their health. Visit EMTexas.com that's EMTexas.com. https://www.medicalnewstoday.com/articles/324427.php Thank you for listening to the Staying Young Medical Minute! With all the mixed messages on health, you need information that you can use and that you can trust. Listen in as the experts discuss all topics health related. It's time to STAY YOUNG and stay healthy! Each week we tackle a topic and often with leading scientists, best-selling authors, and even your favorite celebrities! As a listener of our show, your input is important to us. Please take a moment to fill out this quick survey so we can serve you better - https://survey.libsyn.com/stayingyoung2 For more information on The Staying Young Show, please visit our website at www.StayYoungAmerica.com, and subscribe to the show in iTunes, Stitcher, or your favorite podcast app. You can also reach out to our host, Judy Gaman on www.judygaman.com for book purchasing, and speaking opportunities in your area!
"Iron" Ian discusses his recent trip to America - the effects of eating & activity changes have had and his experience with the western diet.
Ernährung: Der Systemansatz - Abnehmen | Ernährung | Gewohnheiten | #Change The System
Personal Trainer Elizandro Reyes Zamora about Modern Western Diet and Nutritional Trends. I've invited Elizandro to the podcast, because he is an expert in nutrition and fitness. Elizandros Instagram: https://www.instagram.com/elizandrofitness/
Ernährung: Der Systemansatz - Abnehmen | Ernährung | Gewohnheiten | #Change The System
I've invited Elizandro to the podcast, because he is an expert in nutrition and fitness. Elizandro Reyes Zamora was studying sociocultural studies at the university in Cuba. He also has a Master of Science in dance theory. Today he is an entrepreneur and has his own local business in cologne. He trains people in fitness, nutrition and lifestyle who want to take it really serious. In the seventh and eighth episode of the podcast we talk about the fitness lifestyle and psychology of healthy eating in the western world. We talk about the modern western diet and nutritional trends. Zu den Shownotes aus dieser Folge: www.robertsiegers.com/cts-007-interview-modern-western-diet-and-nutritional-trends-elizandro-reyes-english-1-2 Gratis Videokurs "Ernährung verstehen und meistern": www.robertsiegers.com/verstehen
In this episode, I discuss the topic of diet on cognition. I look specifically at the affects of the so-called ‘western diet’, alcohol and caffeine on cognitive skills such as memory and attention, and discuss the contribution of genes and the brain on our ability to choose healthy options. I also talk with Clinical Neuropsychologist, Dr Matthew Hughes, to discuss the affect and management of Type II diabetes on cognition.
In this episode of Mind Pump, Sal, Adam & Justin speak with CaliFlour Foods (www.califlourfoods.com) founder & CEO Amy Lacey and Rachel O'Rourke PR & Events. CaliFlour foods have figured out how to transform a whole head of cauliflower into a single 9" pizza crust using only four natural ingredients. If you are a pizza fan you will definitely want to order some of these crusts. Also, these women have built a multi-million dollar company just in a couple years so if you are a business owner or have aspirations of being a business owner it is a must listen. Find out how a health scare transformed Amy's life and was the origin of CaliFlour Foods. (4:19) CaliFlour Foods the Mind Pump of pizzas! Find out how the power of social media catapulted the company. (10:25) #TheNewWhiteFlour – Find out the benefits of cauliflower. (17:00) The Thrive Market model. Find out how the future of business is e-commerce. (23:05) Do they notice age ranges on their different social media platforms? (24:10) What are they most excited about for their future? (28:00) Find out staying true to who they are is why they continue to grow. (30:14) How did Amy and Rachel meet? Find out even further parallels to Mind Pump. (32:30) Related Links/Products Mentioned: Califlour Foods Pizza Crusts Get your crusts for 20% off using the code MINDPUMP at checkout Intuitive Nutrition Guide - Mind Pump Cottage Food Operations Mediterranean Greek Topped Cauliflower Pizza (with guests from Mind Pump) – YouTube 8 Amazing Health Benefits of Cauliflower Cruciferous Vegetables and Cancer Prevention Thrive Market (MP sponsor) One FREE month's membership $20 Off your first three purchases of $49 or more (That's $60 off total!) Free shipping on orders of $49 or more Cauliflower: The Superfood Health Benefits Role of “Western Diet” in Inflammatory Autoimmune Diseases Featured Guest/People Mentioned: Califlour Foods - Facebook Cauliflower Pizza Crusts (@califlourfoods) Instagram/Twitter Califlour Foods - YouTube Rachel O'Rourke (@rachelorourke) Instagram Amy Lacey Robb Wolf (@robbwolf) Twitter Oprah Winfrey (@Oprah) Twitter Get your crusts for 20% off using the code MINDPUMP at checkout. Go to www.califlourfoods.com. Would you like to be coached by Sal, Adam & Justin? You can get 30 days of virtual coaching from them for FREE at www.mindpumpmedia.com. Get our newest program, MAPS Prime Pro, which shows you how to self assess and correct muscle recruitment patterns that cause pain and impede performance and gains. Get it at www.mindpumpmedia.com! Get MAPS Prime, MAPS Anywhere, MAPS Anabolic, MAPS Performance, MAPS Aesthetic, the Butt Builder Blueprint, the Sexy Athlete Mod AND KB4A (The MAPS Super Bundle) packaged together at a substantial DISCOUNT at www.mindpumpmedia.com. Make EVERY workout better with MAPS Prime, the only pre-workout you need… it is now available at mindpumpmedia.com Also check out Thrive Market! Thrive Market makes purchasing organic, non-GMO affordable. With prices up to 50% off retail, Thrive Market blows away most conventional, non-organic foods. PLUS, they offer a NO RISK way to get started which includes: 1. One FREE month's membership 2. $20 Off your first three purchases of $49 or more (That's $60 off total!) 3. Free shipping on orders of $49 or more Have Sal, Adam & Justin personally train you via video instruction on our YouTube channel, Mind Pump TV. Be sure to Subscribe for updates. Get your Kimera Koffee at www.kimerakoffee.com, code "mindpump" for 10% off! Get Organifi, certified organic greens, protein, probiotics, etc at www.organifi.com Use the code “mindpump” for 20% off. Go to foursigmatic.com/mindpump and use the discount code “mindpump” for 15% off of your first order of health & energy boosting mushroom products. Add to the incredible brain enhancing effect of Kimera Koffee with www.brain.fm/mindpump 10 Free sessions! Music for the brain for incredible focus, sleep and naps! Also includes 20% if you purchase! Please subscribe, rate and review this show! Each week our favorite reviewers are announced on the show and sent Mind Pump T-shirts! Have questions for Mind Pump? Each Monday on Instagram (@mindpumpmedia) look for the QUAH post and input your question there. (Sal, Adam & Justin will answer as many questions as they can)
In the fall of 2017, I had the honor of being one of KetoConnect's first podcast interviewees! Matt and Megha, the champions of all things keto food and keto recipes, asked me to come on and discuss supplements on the keto diet. Matt found me due to my video testing creatine on the keto diet and wanted me to share my other experiences on their “Keto for Normies” podcast. Below is the YouTube video from my Skype feed, which was using my second camera: Mike joins KetoConnect for a Podcast on Keto Supplements https://www.youtube.com/watch?v=HmeAT3dGO6s Citations from the episode Below are notes and links to nearly everything discussed in the episode: Selenium – Low risk for adults, but high impact if missing Two cardiomyopathy case studies, two deaths due to selenium deficiency: Food sources of selenium: Brazil nuts – 1 oz (6-8 nuts): 544 mcg (over 100% DV) Yellowfin tuna (over 100%) Halibut (67% DV) Sardines (64% DV) Grass-fed beef (47% DV) Turkey (44% DV) Beef liver (40% DV) Chicken (31% DV) Egg (21% DV) Spinach (16% DV) https://pubmed.ncbi.nlm.nih.gov/12681013 https://pubmed.ncbi.nlm.nih.gov/22367552 https://pubmed.ncbi.nlm.nih.gov/19027591 (QT Prolongation) Electrolytes First, some disclaimers: Regarding the FDA – Do we believe them or not? After all, their recommendations aren't even feasible without massive supplementation using the diets, they recommend! (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878634/) However, their ratios of potassium to sodium should be a good starting point… meaning potassium is going to be difficult without some ‘help'. Yet, there are no truly agreed upon ratios All in all, it's going to come down to getting your own blood tests and gut-checking with how you're feeling and if you're cramping. On to the important electrolytes: Magnesium Nearly everyone needs to supplement this! Western Diet is simply deficient. (See best forms of magnesium) Better sleep, less anxiety Regular Poops!! Food sources: Dark leafy greens, fish, nuts Sodium Less insulin â more sodium and water excreted Lyle McDonald says 5g? But only 1g potassium? Not sure we agree, but again… blood tests. Recommended reading: The Salt Fix Potassium Western dieters are low in general. USDA = 4.7g/day! (https://ods.od.nih.gov/Health_Information/Dietary_Reference_Intakes.aspx links to https://www.nap.edu/read/10925/chapter/7#187: On the basis of available data, an Adequate Intake (AI) for potassium is set at 4.7 g (120 mmol)/day for all adults. That... Read more on the PricePlow Blog
Here's a 1 minute preview of today's featured Guest. Give it a listen and share it with your friends, and if you like the content be sure and listen to the full 20 minute interview! Transcript: Bill: Looking for a quick dietary tip to reduce your risk of cancer? Here's Doctor David Leonardi. David: Most people are convinced that protein is a critical part of our nutrition, and the consumption of plenty of animal protein is pretty standard in the Western Diet. But, we've long known from published studies, that high protein diets on a bio-chemical level, are actually deleterious. So, recently, a study published in 2014 finally looked at the relationship between protein intake and mortality In people aged 50-65, the intake of animal protein, in this study, correlated directly with mortality. Now, when I say animal protein, almost everybody thinks of red meat, but I'm talking about animal protein in general. So, this includes all meat, fish, eggs, and dairy. So the intake of animal protein correlated directly with mortality in people aged 50-65, but when they looked at plants as the source of protein, the relationship with mortality was nearly abolished. And there's several reasons for this, number one: animal protein contains higher levels of an amino acid called methionine, and cancer cells thrive on methionine. Secondly, Bill, how do we usually cook animal protein? Meat or fish, we usually grill it or broil it. These very hot or very dry cooking processes form carcinogens on the surface of the meat or fish called heterocyclic amines, and they create inflammatory molecules within the meat or fish. All these create a bio-chemical environment that promotes the risk of a mutation to cancer, and also more rapid growth of that cancer. Need to work ON your business? Start with a free assessment at www.BizGrowth123.com
Episode 012 - Current Western Diet In today's episode we discuss more about how current American diets are moving farther away from the healthy meals we once had.
The majority of children and adults in America take one or more dietary supplements every day. Today's dietary supplements include vitamins, minerals, herbals and botanicals, amino acids, enzymes and many other products. Popular supplements include vitamins D and E; minerals like magnesium, calcium, potassium, and iron, herbs such as echinacea and garlic; and specialty products like probiotics and fish oils. Yet, by the time you finish reading this email another four Americans will have had a heart attack and another four will have had a stroke or heart failure. Heart attack is the leading killer in developed countries. Worldwide, cancer kills 7.6 million people annually. Deaths from cancer are projected to reach over 11 million by 2030. Throughout the world 171 million people have been diagnosed with diabetes and over 500 million people are clinically obese. As per the World Health Organization, obesity is a leading preventable cause of death worldwide and authorities view it as one of the most serious public health problems of the 21st century. What is going on and why are we so sick? After 45 years of her own research Dr. Dean has come to two very important understandings: 1) Magnesium and mineral deficiency are the real 'killers' 2). Many of the symptoms people are expressing today also come from digestive issues and the Western Diet - highly processed foods high in sugar and fats that infest the gut with yeast overgrowth. If you are unfamiliar with yeast overgrowth - you can read this article written by Dr. Carolyn Dean that describes its causes and effects: http://www.needs.com/product/NDNL-0704-01/a_Probiotics Tonight on our internet based radio show, we talked with Dr. Dean's about her findings as well as her recommendation for treating these two foundational issues with a doctor created, doctor recommended protocol that will move you out of the 'risk' column and into the 'reward' program!
The majority of children and adults in America take one or more dietary supplements every day. Today's dietary supplements include vitamins, minerals, herbals and botanicals, amino acids, enzymes and many other products. Popular supplements include vitamins D and E; minerals like magnesium, calcium, potassium, and iron, herbs such as echinacea and garlic; and specialty products like probiotics and fish oils. Yet, by the time you finish reading this email another four Americans will have had a heart attack and another four will have had a stroke or heart failure. Heart attack is the leading killer in developed countries. Worldwide, cancer kills 7.6 million people annually. Deaths from cancer are projected to reach over 11 million by 2030. Throughout the world 171 million people have been diagnosed with diabetes and over 500 million people are clinically obese. As per the World Health Organization, obesity is a leading preventable cause of death worldwide and authorities view it as one of the most serious public health problems of the 21st century. What is going on and why are we so sick? After 45 years of her own research Dr. Dean has come to two very important understandings: 1) Magnesium and mineral deficiency are the real 'killers' 2). Many of the symptoms people are expressing today also come from digestive issues and the Western Diet - highly processed foods high in sugar and fats that infest the gut with yeast overgrowth. If you are unfamiliar with yeast overgrowth - you can read this article written by Dr. Carolyn Dean that describes its causes and effects: http://www.needs.com/product/NDNL-0704-01/a_Probiotics Tonight on our internet based radio show, we talked with Dr. Dean's about her findings as well as her recommendation for treating these two foundational issues with a doctor created, doctor recommended protocol that will move you out of the 'risk' column and into the 'reward' program!
http:/www.einstein.yu.edu - The Western Diet -- defined by fried and sweet foods, processed and red meat, refined grains and high-fat dairy products -- has been liked to colon cancer. Leonard Augenlicht, Ph.D., explains his research into how diet impacts the colon and the development of the disease. Dr. Augenlicht is director of Einstein's Biology of Colon Cancer Program and a professor of medicine and of cell biology at Albert Einstein College of Medicine.
Omega-3s are indeed a hot topic, although it appears that all we North Americans really know, is that Omega-3 eggs, fish and fish oils, and flax products, are all good sources. Consuming these products as we've been told, reduces the risk of heart disease. Of course the responsible thing to do is to remain skeptical and question any new diet craze that hits our culinarily confused culture. As for Omega-3s, it appears some critical information has evaded the radar of North American media and hence the eating public. In a fascinating book by Author Susan Allport, the history, science and hype surrounding Omega-3s is laid out for all to see. Titled "The Queen of Fats - Why Omega-3s Were Removed From the Western Diet and What We Can Do to Replace Them", Allport reveals that our collective understanding of these vital fatty acids is way off. According to Allport, lacking in exposure has been Omega-6s, another family of essential fatty acids that compete with Omega-3s. And so if both are in competition, why is it we never hear about the 6s? In October 2007, CBC's The National aired a segment on the increasing confusion surrounding Omega-3s and questioned how much fish new and expecting mothers should be consuming. After a read through The Queen of Fats, it appears that not only has the CBC deepened this collective confusion, it has equally encouraged the further pillaging of our already vulnerable oceans. Unlike most media coverage on diet and nutrition, this episode will not so much suggest what you should or should not be eating, but will instead look to capture how our lifestyles and the industrialization of our food has had devastating impacts on our health. We also hear segments from a September 2007 interview between Host Jon Steinman and Cargill Canada President, Len Penner. Guests/Voices Susan Allport, Author, The Queen of Fats (Katonah, NY) - An award-winning writer for publications such as the New York Times and Gastronomica, Susan Allport has spent the past decade exploring how food shapes behavior and health. In 2006, University of Calfornia Press published her book The Queen of Fats: Why Omega-3s Were Removed from the Western Diet and What We Can Do to Replace Them. JoAnne Buth - President, Canola Council of Canada (Winnipeg, MB) - A national trade association representing producers, input suppliers, processors and marketers of canola and its products. Len Penner - President, Cargill Canada (Winnipeg, MB) - One of Canada's largest agricultural merchandisers and processors with interests in meat, egg, malt and oilseed processing, livestock feed, salt manufacturing, as well as crop input products, grain handling and merchandising. The company is a subsidiary of Cargill Limited based in the United States. In February 2007, Deconstructing Dinner ran a 2-part series on the operations of the company.
Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 07/19
Übergewicht hat in den letzten Jahrzehnten weltweit epidemischen Charakter erreicht. In Europa sind bereits 43% der erwachsenen Bevölkerung übergewichtig und 17% fettleibig. Die Adipositas ist eine multifaktorielle Erkrankung und führt über ein erhöhtes Risiko für Diabetes, Krebs oder Herz-Kreislauferkrankungen bis hin zu einer deutlichen Herabsetzung der Lebenserwartung. Durch das Versagen konventioneller Therapien wie Diät oder Sport, treten medikamentöse Behandlungsmethoden immer mehr in den Vordergrund. Bisher sind zwei Kategorien etabliert, die Appetitzügler und die Lipasehemmer. Zahlreiche Studien erforschen neuerdings Therapiekonzepte zum Angriff an spezifischen Rezeptoren und Veränderungen des Fett- und Energiestoffwechsels auf molekularer Ebene. Diese Arbeit beschäftigte sich mit der Entwicklung neuer Arzneimittel zur Behandlung von Adipositas in verschiedenen Fettsuchtmodellen an Ratten. Alle Studien begannen mit Vorversuchszeiten von 1-2 Wochen zur Stabilisierung des täglichen Körpergewichtzuwachses, der Futter- und der Wasseraufnahme. Die Tiere erhielten in allen Versuchen eine zucker- und fettreiche Diät, deren Zusammensetzung sich an Ernährungsgewohnheiten in westlichen Industrieländern orientierte (Western Diet). Wasser wurde ad libitum bereitgestellt und die Aufnahme täglich bestimmt. Das gleich galt mit Ausnahme von Versuch 1 auch für das Futter. Am letzten Tag der Experimente erfolgten Blutabnahmen an den zuvor nüchtern gesetzten Ratten. Unmittelbar danach wurden die Tiere in einer CO2-Kammer getötet, die Kadaver einzeln in Gefrierbeutel verpackt und anschließend zusammen mit den Blutproben bis zur weiteren Aufarbeitung gruppenweise bei -20 °C eingefroren. Versuch 1: In Versuch 1 wurde an männlichen Wistarratten eine mögliche Wirkungsverstärkung des selektiven CB1-Antagonisten SLV319 in Kombination mit dem Lipasehemmer Orlistat (Xenical®), auf Körpergewichtsentwicklung, Futter- und Wasseraufnahme, Blutwerte und Zusammensetzung der Tierkörper untersucht. Die Tiere wurden über einen Zeitraum von 4 Wochen einmal täglich mit Vehikel 1 (CMC) oder SLV319 (3 oder 10 mg/kg KG) geschlündelt, und zweimal täglich mit Vehikel 2 (Labrasol) oder Orlistat 50 mg/kg KG. Jeweils nach Gabe von entweder Labrasol oder Orlistat erhielten die Ratten für genau 2,5 Stunden Futter ad libitum. Das Körpergewicht der Tiere war in allen Gruppen im Vergleich zur Kontrolle vermindert: Bei Einzelbehandlung mit SLV319-3 um 50%, mit SLV319-10 um 42% und mit Orlistat um 52%, bei der Kombination tendenziell aber nicht signifikant stärker durch SLV319-3+Orlistat um 76% und durch SLV319-10+Orlistat um 59%. Die Futteraufnahme in Relation zum Körpergewicht wurde im Vergleich zur Kontrolle durch die niedrige und die hohe SLV319-Dosis um 8 bzw. 10% vermindert und durch Orlistat um 18% erhöht. In der Kombination erhöhte sich Futteraufnahme ebenfalls um 11% bzw. 13%. Zusätzlich erniedrigte sowohl SLV319 als auch Orlistat die Triglyzeride, NEFA-Level, das freie Cholesterin, und hatte einen positiven Effekt auf die HDL-Werte im Serum. SLV319 erniedrigte die Insulinspiegel und verbesserte die Insulinsensitivität. In der Carcass-Analyse konnte in allen Gruppen der Körpergewichtsverlust überproportional auf eine Verminderung an Körperfett zurückgeführt werden. SLV319 hat somit ein mögliches Potenzial für die Therapie der Fettleibigkeit, die durch Kombination mit Orlistat noch verstärkt werden könnte. Versuch 2: Die vorliegende Studie erforscht die Auswirkungen von SLV335, einem neuen Carboanhydrasehemmer, auf Körpergewicht, Futter-, Wasseraufnahme und Blutwerte bei weiblichen Wistarratten im Vergleich zu Topiramat. Die Tiere wurden über einen Zeitraum von 4 Wochen zweimal täglich mit Vehikel, SLV335 oder Topiramat geschlündelt. Die Tagesdosen von jeweils 30, 60 oder 100 mg/kg KG wurden zu einem Drittel am Morgen und zu zwei Dritteln am Abend verabreicht. Sowohl SLV335 als auch Topiramat erniedrigten signifikant und dosisabhängig das Körpergewicht der Tiere im Vergleich zur Kontrolle: Bei den drei SLV335-Dosen um 18%, 52% und 85%, bei Topiramat um 38%, 40% und 58%. Auch die Futteraufnahme relativ zum Körpergewicht reduzierte sich, aber nur bei SLV335 um 9%, 15% und 23%, bei allen Topiramat-behandelten Ratten um 11-13%. Topiramat und SLV335 führten unabhängig von der Dosis zu einer Steigerung der Wasseraufnahme, die sich aber nur bei Topiramat signifikant von der Kontrolle unterschied. Weder Topiramat noch SLV335 zeigten signifikante Änderungen der Blutwerte, doch erniedrigten sie leicht die Triglyzeride und NEFA-Werte im Serum. Der CA-Inhibitor SLV335 hatte einen stark gewichtsreduzierenden Effekt. Somit könnte die Hemmung spezifischer Carboanhydrasen ein Mechanismus für Gewichtsverlust sein, und SLV335 ein therapeutisches Potenzial in der Behandlung der Adipositas besitzen. Versuch 3: In diesem Versuch wurden zwei CB1-Antagonisten, das bereits im Handel befindliche Rimonabant (Acomplia®) und die Prüfsubstanz SLV330 in ihren Wirkungen auf Köpergewicht, Futter-, Wasseraufnahme und die Blutwerte bei männlichen Wistarratten verglichen. Die Tiere wurden einmal täglich 2 Wochen lang entweder mit CMC-PEG-Vehikel oder mit 3 oder 10 mg/kg KG SLV330 bzw. Rimonabant i.p. gespritzt. Sowohl SLV330 als auch Rimonabant erniedrigten das Körpergewicht der Ratten im Vergleich zu Kontrolle: Bei der niedrigen und hohen Dosis von SLV330 um 25% und 70%, bei Rimonabant um 37 und 60%. Die Futter- und Wasseraufnahme wurde in allen Gruppen ebenfalls dosisabhängig erniedrigt. Beide Substanzen erniedrigten die Triglyzeride, NEFA und freies Cholesterin im Serum. Lediglich die hohe Rimonabantdosis erhöhte das HDL, verbesserte die Insulinsensitivität und erniedrigte die Insulinspiegel im Serum. Diese Ergebnisse zeigen, dass SLV330 durchaus Potenzial für die Therapie der Adipositas besitzt. Intraperitoneal verabreicht zeigt es vergleichbare Ergebnisse zu Rimonabant. Versuch 4: Die dosisabhängige Wirkung von Topiramat auf Körpergewicht, Futter-, Wasseraufnahme, Blutwerte und Zusammensetzung der Tierkörper wurde an männlichen Zucker-Ratten untersucht, die erstmals mit einer fettreichen „Western Diet“ gefüttert wurden. Die Tiere wurden zweimal täglich über einen Zeitraum von 4 Wochen entweder mit CMC-PEG-Vehikel oder Topiramat (30 oder 100 mg/kg KG) geschlündelt. Das Körpergewicht der Tiere verminderte sich je in der niedrigen und hohen Topiramatdosis im Vergleich zur Kontrolle um 10% bzw. 32%. Auch die Futteraufnahme wurde dosisabhängig unterdrückt. Die Wasseraufnahme steigerte sich dagegen bei der niedrigeren Dosis stärker als bei der hohen Dosis. Unabhängig von der Dosis erhöhte Topiramat im Serum die Triglyzeride, NEFA und LDL und wirkte sich negativ auf das HDL aus. Das gesamte und freie Cholesterin erhöhte sich, die Insulinsensitivität wurde nicht verändert. Die geringe Gewichtsreduktion nach der niedrigen Topiramatdosis konnte fast vollständig auf den Fettverlust zurückgeführt werden, wohingegen die hohe Dosis eine gleichmäßige nicht-spezifische Erniedrigung an Fett, Wasser und etwas weniger an Proteinen bewirkte. Die gewichtsreduzierenden Eigenschaften von Topiramat wurden bestätigt. Vor allem die niedrigere Dosierung von 30 mg/kg führt möglicherweise zu metabolischen Veränderungen, welche eine Verminderung des Körperfetts bewirken.
Background: The atheroprotective effects of systemic delivery of either apolipoprotein A-I (wtApoA-I) or the naturally occurring mutant ApoA-I Milano (ApoA-I(M)) have been established in animal and human trials, but direct comparison studies evaluating the phenotype of ApoA-I or ApoAI-Milano knock-in mice or bone marrow transplantated animals with selectively ApoA-I or ApoAI-Milano transduced macrophages give conflicting results regarding the superior performance of either one. We therefore sought to compare the two forms of apoA-I using liver-directed somatic gene transfer in hypercholesterinemic mice - a model which is most adequately mimicking the clinical setting. Methods and results: Vectors based on AAV serotype 8 (AAV2.8) encoding wtApoA-I, ApoA-I(M) or green fluorescent protein (GFP) as control were constructed. LDL receptor deficient mice were fed a Western Diet. After 8 weeks the AAV vectors were injected, and 6 weeks later atherosclerotic lesion size was determined by aortic en face analysis. Expression of wtApoA-I reduced progression of atherosclerosis by 32% compared with control (p = 0.02) and of ApoA-I(M) by 24% (p = 0.04). There was no significant difference between the two forms of ApoA-I in inhibiting atherosclerosis progression. Conclusion: Liver-directed AAV2.8-mediated gene transfer of wtApoA-I and ApoA-I(M) each significantly reduced atherosclerosis progression to a similar extent.