Podcasts about Mash

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Best podcasts about Mash

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Latest podcast episodes about Mash

Homebrew Happy Hour
Open vs Closed Transferring, Planning Out Future Brew Days, Improving Mash Efficiency in Igloo Coolers, & Does the Yeast Strain Really Matter – Ep. 452

Homebrew Happy Hour

Play Episode Listen Later Nov 6, 2025 67:17


I'm so excited to welcome back my good friend, Lorena Evans (from BrewersFriend.com) as she helps me take YOUR questions and solve all of the world's problems in a single podcast episode. Can you believe it?! Buckle up – it's time for the Homebrew Happy Hour podcast!… THE home brew #podcast where we answer all […]

Inside Matters
Fatty Liver, Gut Health, andFunctional Medicine - Dr Guy Neff

Inside Matters

Play Episode Listen Later Nov 6, 2025 70:23


Revolutionising Liver Health: The Link Between Gut Health, Genetics, and Lifestyle In this episode, we dive deep into the intricate connections between liver health, gut health, genetic predispositions, and lifestyle factors. Our guest, Gary, a seasoned physician and entrepreneur, shares his extensive experience from pioneering liver disease research in the 90s to running a successful metabolic clinic focused on functional medicine today. Learn about the evolution of understanding fatty liver diseases like NASH and MASH, the impact of processed foods, and the groundbreaking treatments emerging, including the promising effects of GLP-1 therapies. Gary also discusses the pivotal role of a clean diet, exercise, and quality sleep in managing liver health, and the challenges of implementing these changes in a clinical setting. Don't miss this insightful conversation packed with practical advice and forward-thinking approaches to improving liver and overall metabolic health. 00:00 The State of Food Quality in America vs Scotland 02:39 Understanding Fatty Liver Disease: Past and Present 05:29 Genetic and Environmental Factors in Fatty Liver Disease 08:13 The Evolution of MASH: From NASH to Metabolic Health 10:46 Emerging Treatments and Medications for Liver Disease 13:35 The Role of GLP-1s in Managing Liver Health 16:18 The Gut–Liver Connection: A Historical Perspective 19:07 Building a Successful Liver Clinic: Insights and Challenges 33:52 Understanding Metabolic Health and Genetic Testing 35:13 The Importance of Gut Health 37:39 Transforming Workplace Wellness Initiatives 45:48 The Future of Functional Medicine 51:30 Addressing Liver Health and Alcohol Consumption Takeaways The quality of food in America is declining, impacting health. Fatty liver disease is increasingly common, especially among those with higher body mass indexes. Genetic predisposition plays a significant role in liver disease. MASH is a critical condition that combines fatty liver with inflammation. Advancements in GLP-1 medications show promise for treating liver disease. Gut health is essential for overall wellness and liver health. Guy Neff's journey reflects a blend of medicine and business acumen. Building a successful liver clinic requires navigating numerous challenges. Functional medicine is gaining traction as a holistic approach to health. Routine testing for liver health is crucial for early detection and intervention. You must not rely on the information in this video as an alternative to medical advice from your doctor or other professional healthcare provider. If you have any specific questions about any medical matter you should consult your doctor or other professional healthcare provider. If you think you may be suffering from any medical condition you should seek immediate medical attention. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of the information in this podcast.

Barbell Shrugged
Rebuilding Strength and Purpose, Travis Mash's Path Back to the Platform w/ Anders Varner, Travis Mash and Doug Larson #822

Barbell Shrugged

Play Episode Listen Later Nov 5, 2025 41:47


In this episode, Anders Varner, Doug Larson, and Travis Mash sit down for a story that is equal parts comeback and evolution. After a hip replacement and years away from competition, Mash, now over 50 years old, stepped back onto the powerlifting platform to go nine for nine and set new age group world records. He breaks down how he rebuilt his body, balanced strength with health, and used velocity-based training to stay powerful without breaking down. The crew digs into how technology, recovery, and smarter training allow veteran lifters to keep progressing long after their prime years, and why Mash believes everyone over 50 should use bar speed tracking to train safely and effectively. Travis opens up about his modern approach, tracking VO₂ max, focusing on sleep quality, and embracing conditioning as a secret weapon most powerlifters ignore. He explains why he is competing just twice a year from now on, the methods that rebuilt his deadlift after chronic back pain, and how discipline has replaced the reckless intensity of his younger days. His goal is not just to lift big again, but to model longevity, work ethic, and integrity for his kids. The conversation turns deeply personal when Mash shares how his son's recent basketball tryout failure became a father-son lesson in resilience. From youth sports to elite competition, the group reflects on how loss, hard work, and long-term consistency shape champions. They also swap stories of athletic breakthroughs, from Doug's failed baseball tryout that launched his strength career to Anders' early lifting days and the raw power of athletes like Ed Coan and Ryan Fischer. This episode is a look at what it means to age as an athlete, how to stay in the game, keep the fire alive, and prove that strength and purpose do not fade with time. Work With Us: Arétē by RAPID Health Optimization   Links: Anders Varner on Instagram Doug Larson on Instagram Coach Travis Mash on Instagram

The Brülosophy Podcast
Episode 403 | Impact Mash Temperature Has On Belgian Golden Strong Ale

The Brülosophy Podcast

Play Episode Listen Later Nov 4, 2025 66:38


Brülosophy merch is now available - click here to see all we have to offer! Contributor Andy Carter joins Marshall to discuss mash temperature and particularly the impact it has on Belgian Golden Strong Ale. Become a Brülosophy Patron today and be rewarded for your support! | Relevant Article | Mash Temperature: Low Vs. High In A Belgian Golden Strong Ale xBmt

The Aggressive Life with Brian Tome
MAN CAMP & Masculinity That is Good and Getting Better with Jim Burgen—Pastor, Outdoorsman

The Aggressive Life with Brian Tome

Play Episode Listen Later Nov 4, 2025 69:15


Something powerful happens when thousands of men leave comfort behind and unite in pursuit of God. Just under a week after attending his first MAN CAMP, Jim Burgen joins Brian on The Aggressive Life to talk about his experience—from speaking under the big tent, to conversations outside MASH, to why MAN CAMP gives him hope that masculinity is good and getting better. Jim also shares what it means to age aggressively, why it's important to keep doing new things, and what it takes to be a man who refuses to coast. From elk hunts, to hard workouts, to spiritual warfare, this is a no-holds-barred conversation about becoming the kind of man the world needs.  Learn more about MAN CAMP at www.mancamp.us  Watch this week's episode on YouTube here.

TV Guidance Counselor Podcast
TV Guidance Counselor Episode 713: Eric Miller

TV Guidance Counselor Podcast

Play Episode Listen Later Nov 3, 2025 89:58


December 27, 1980 - January 2, 1981   This week Ken welcomes author, screenwriter, movie maker Eric Miller (ericmillerwrites.com) to the show. Ken and Eric discuss satellites, the creepy paying with your palm technology at Whole Foods, when Sci-Fi actually predicts the future, Dawn of the Dead, The Running Man, Hell House, The Haunting of Hell House vs The Haunting, story prompts, Shirly Jackson, Richard Matheson, Magnum PI, how prevalent Vietnam vets were in 80s pop culture, PTSDT, the importance of character, dark sense of humor, dealing with serious topics, how you need rules to kick against, why having no problems to solve actually makes worse art, how amazing it is that anything produced in Hollywood is ever good, Full Moon Pictures, Crash and Burn, Bill Mosley, life long friends, directing Orson Wells, working with legends, Phantasm, being an intern, cigarettes, Umph in Triumph, being from Indiana, David Letterman, Breaking Away, learning there is a TV series based on your favorite movie, how everything is more or less streaming for free if you know where to look, Schlitz vs Bud in the Great American Beer Switch, Mark Twain, Hal Holbrook, Grace Kelly, variety shows, the M*A*S*H finale, gallows humor, how sometimes an awful toxic workplace can still produce a good end product, Real People, That's Incredible!, The White Shadow, Mud Wrestling, New Year's Eve, Bonanza, cop shows, setting the tone, The Muppet Movie, the NBA, basketball, Meet the Feebles, Peter Jackson, how nobody can really attain the levels of fame people had in the second half of the 20th century, Bob Cousy, Secret Agent Man, Branded, Larry Cohen, Dexter and how being a fan of television often leads us to reverse engineer story telling and interact with people (not kill them).  ALSO Ken is giving away a pair of tickets to the 945 Arts at the Armory show on November 13th where Ken will be opening for Janeane Garofalo. If you can tell Ken the reason Loren Michaels gave Janeane for why she couldn't quit SNL, email it to tvguidancecounselor@gmail.com and you will get a pair of tickets for the show.  

Prestige-ish Media
It: Welcome to Derry - Season One Episode Two - INSTANT REACTION - The Thing in the Dark

Prestige-ish Media

Play Episode Listen Later Nov 3, 2025 83:21


In this episode of The Prestige-ish Media Podcast - Craig Lake, Dan McNair and Shauna Schoenborn give their INSTANT REACTION to the new HBO Max series It: Welcome to Derry Season One Episode Two - The Thing in the Dark. In this episode we discuss Majors, Mash, more childbirth, pickles, Norman Rockwell, and more. Please continue to join us for our ongoing Prestige-ish Media Podcast coverage of the HBO Max show - It: Welcome to Derry. Coming soon join us for our coverage of Stranger Things Season 5 on Netflix and Fallout Season 2 on Amazon Prime Video.Please check out our website at http://prestigeish.com, follow our podcasts on all your favorite podcast platforms, and leave us positive reviews if you enjoy our show. X @prestige_ish Instagram @prestigeishmedia X/Instagram @realrealbatman @danmcnair1017 @neverboredhousewife http://prestigeish.com

Keeping Current
Emerging Therapies for MASH: From Theory to Clinical Practice

Keeping Current

Play Episode Listen Later Nov 3, 2025 35:49


How much do you know about new therapies for treating fibrosis in MASH and the patients who can benefit most from them? Credit available for this activity expires: 10/29/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003068?ecd=bdc_podcast_libsyn_mscpedu

Deadass Podcast
Ep.244 - The Graveyard Shift

Deadass Podcast

Play Episode Listen Later Nov 3, 2025 71:17


Today on the Deadass Podcast, Big Sexy and Papi jump on for another edition of the Graveyard Shift. The lads come in a day earlier to record the episode and Bryze shares his effort of trying to do a 30 hour fast while Zaden shares an amazing receipe of Bangers and Mash on Hotdog buns. We here an update from a Pallbearer who took our advice and bought himself a 200 series landcruiser. We reflect on our music we are currently listening too and Big Sexy enlightens us with 2 "Humans doing amazing things" Hosted on Acast. See acast.com/privacy for more information.

MASH Matters
Counterfeit Klinger? - MASH Matters #144

MASH Matters

Play Episode Listen Later Nov 1, 2025 53:41


Sparky? Please connect Jeff & Ryan with a big batch of voicemails. In this episode, we hook up the ol' answering machine to play messages from YOU! Topics include painless dentistry, BJ's jerky mustache, real-life Klinger schemes, M*A*S*H music, buying the cookbook, Netflix, hating on "Dreams," The Love Boat, and more. Plus, who the heck IS that guy wearing Klinger's curlers?   Support the podcast on Patreon and buy merch at the MASH Matters store   For show notes, episodes, recipes, bios, and more visit our website.  

The CyberWire
The Malware Mash!

The CyberWire

Play Episode Listen Later Oct 31, 2025 3:06


Happy Halloween from the team at N2K Networks! We hope you share in our Halloween tradition of listening to the Malware Mash. You can check out our video ⁠here⁠. Lyrics I was coding in the lab late one night when my eyes beheld an eerie sight  for my malware threat score began to rise  and suddenly to my surprise... It did the Mash  It did the Malware Mash  The Malware Mash  It was a botnet smash  It did the Mash  It caught on 'cause of Flash  The Malware Mash  It did the Malware Mash From the Stuxnet worm squirming toward the near east  to the dark web souqs where the script kiddies feast  the APTs left their humble abodes  to get installed from rootkit payloads.  They did the Mash  They did the Malware Mash  The Malware Mash  It was an adware smash  They did the Mash  It caught on 'cause of Flash  The Malware Mash  They did the Malware Mash The botnets were having fun  The DDoS had just begun  The viruses hit the darknet,  with ransomware yet to come.  The keys were logging, phishing emails abound,  Snowden on chains, backed by his Russian hounds.  The Shadow Brokers were about to arrive  with their vocal group, "The NotPetya Five." They did the Mash  They played the Malware Mash The Malware Mash  It was a botnet smash  They did the Mash  It caught on 'cause of Flash  The Malware Mash  They played the Malware Mash Somewhere in Moscow Vlad's voice did ring  Seems he was troubled by just one thing.  He opened a shell then shook his fist  and said, "Whatever happened to my Turla Trojan twist."  It's now the Mash  It's now the Malware Mash  The Malware Mash  And it's a botnet smash  It's now the Mash  It caught on 'cause of Flash  The Malware Mash  It's now the Malware Mash Now everything's cool, Vlad's a part of the band  And the Malware Mash is the hit of the land.  For you, defenders, this mash was meant to  when you get to my door, tell them Creeper sent you. Then you can Mash  Then you can Malware Mash  The Malware Mash  And be a botnet smash  It is the Mash  Don't you dare download Flash  The Malware Mash  Just do the Malware Mash Learn more about your ad choices. Visit megaphone.fm/adchoices

Hacking Humans
The Malware Mash!

Hacking Humans

Play Episode Listen Later Oct 31, 2025 3:06


Happy Halloween from the team at N2K Networks! We hope you share in our Halloween tradition of listening to the Malware Mash. You can check out our video ⁠here⁠. Lyrics I was coding in the lab late one night when my eyes beheld an eerie sight  for my malware threat score began to rise  and suddenly to my surprise... It did the Mash  It did the Malware Mash  The Malware Mash  It was a botnet smash  It did the Mash  It caught on 'cause of Flash  The Malware Mash  It did the Malware Mash From the Stuxnet worm squirming toward the near east  to the dark web souqs where the script kiddies feast  the APTs left their humble abodes  to get installed from rootkit payloads.  They did the Mash  They did the Malware Mash  The Malware Mash  It was an adware smash  They did the Mash  It caught on 'cause of Flash  The Malware Mash  They did the Malware Mash The botnets were having fun  The DDoS had just begun  The viruses hit the darknet,  with ransomware yet to come.  The keys were logging, phishing emails abound,  Snowden on chains, backed by his Russian hounds.  The Shadow Brokers were about to arrive  with their vocal group, "The NotPetya Five." They did the Mash  They played the Malware Mash The Malware Mash  It was a botnet smash  They did the Mash  It caught on 'cause of Flash  The Malware Mash  They played the Malware Mash Somewhere in Moscow Vlad's voice did ring  Seems he was troubled by just one thing.  He opened a shell then shook his fist  and said, "Whatever happened to my Turla Trojan twist."  It's now the Mash  It's now the Malware Mash  The Malware Mash  And it's a botnet smash  It's now the Mash  It caught on 'cause of Flash  The Malware Mash  It's now the Malware Mash Now everything's cool, Vlad's a part of the band  And the Malware Mash is the hit of the land.  For you, defenders, this mash was meant to  when you get to my door, tell them Creeper sent you. Then you can Mash  Then you can Malware Mash  The Malware Mash  And be a botnet smash  It is the Mash  Don't you dare download Flash  The Malware Mash  Just do the Malware Mash

The Seth Leibsohn Show
Movie and TV Recommendations, Kamala Harris, and the Biden Autopen Presidency (Guest Ed Morrissey)

The Seth Leibsohn Show

Play Episode Listen Later Oct 31, 2025 36:15


Ed Morrissey, Managing Editor at Hot Air, and host of the Ed Morrissey Podcast, joins Seth to discuss movie recommendations, former Vice President Kamala Harris’s recent interview with Sarah Ferguson, the television show M*A*S*H, the newly-released House Committee on Oversight and Government Reform staff report entitled “The Biden Autopen Presidency,” and Eli Lake’s piece at The Free Press, “Did America Have a Functioning President in 2024?”See omnystudio.com/listener for privacy information.

It's Mike Jones
Mike Jones Minute-Con 10/31/25

It's Mike Jones

Play Episode Listen Later Oct 31, 2025 1:06 Transcription Available


South Park has new mischief tonight and a Monster Mash movie is coming! We'll have it all for you in the #MikeJonesMinuteCon.

Trivia Tracks With Pryce Robertson
Monster Mash

Trivia Tracks With Pryce Robertson

Play Episode Listen Later Oct 31, 2025 2:36 Transcription Available


A perennial Halloween favorite, the novelty song "Monster Mash" was released in August 1962, and hit No. 1 on the charts two months later, just in time for Halloween. The song re-entered the Billboard Hot 100 at number 37 in 2021, nearly 60 years after its release.

BioSpace
Novartis' Big Buy, Q3 Earnings, Regeneron's Dropped Cell Therapy, More

BioSpace

Play Episode Listen Later Oct 29, 2025 26:36


Novartis started the week early with a Sunday afternoon announcement of the acquisition of neuromuscular drug developer Avidity Biosciences for $12B. That's the second biggest buy of the year after Johnson & Johnson's January acquisition of Intra-Cellular. The Avidity buy could read through positively to Dyne Therapeutics, as both are aiming to treat neuromuscular ailments with RNA-targeting therapies. Dyne shares have nearly doubled over the past month, jumping approximately 40% after Novartis' news dropped.  The Avidity deal is the latest in an uptick on the pharma M&A front. Also this week, Eli Lilly doubled down on gene therapy with a pick up of Adverum Biotechnologies and its lead program for wet age-related macular degeneration. And Roche, which last month acquired 89bio in a $3.5 billion deal centered on a MASH candidate, said in its third-quarter earnings call on Thursday that more deals could be in the future. Finally, beyond the big guys, Leerink Partners predicts which small- to mid-cap firms might also be on the hunt for new pipeline goodies.  Following the dealmaking news, Novartis held its earning call on Tuesday. CEO Vas Narasimhan downplayed the deals Pfizer, AstraZeneca and Amgen have made with the White House, saying they don't address the root of the drug pricing problem President Donald Trump hopes to solve.   On other earnings calls, BioMarin announced plans to divest the hemophilia gene therapy Roctavian. Regeneron faced further questions about Eylea and issues with the Catalent plant that's been tripping up its regulatory applications. But the company didn't address last week's news that it was dropping a CAR T asset picked up from 2seventy bio. These are but two of the latest examples of underperforming assets in the cell and gene therapy space.  BridgeBio had positive news for patients with limb-girdle muscular dystrophy this week after acing a Phase III trial for an investigational substrate supplementation therapy. Analysts predict the asset could be before the FDA later this year or early next.   Finally, with the U.S. government shutdown going on a month, BioSpace takes a look at how the FDA is operating. 

UEG Talks
Best of UEG Week - DDM Summit with Francisco Real

UEG Talks

Play Episode Listen Later Oct 28, 2025 23:13 Transcription Available


Join Julia Mayerle and Francisco X. Real (Paco) as they reflect on the first-ever Digestive Disease Mechanism (DDM) Summit, introduced during UEG Week 2025 in Berlin. In this special episode, they discuss how the DDM Summit brought together leading scientists and clinicians to explore the mechanisms driving GI cancers — from colorectal to pancreatic and liver cancer. Hear how cutting-edge discoveries in genomics, metabolism, and tumour microenvironment are already shaping translational research and clinical trials. Julia and Paco also share highlights from the meeting, including exciting poster sessions, emerging collaborations, and their vision for the next DDM Summit focusing on inflammation in GI disease. - 08:00 The evolution of colitis-associated colorectal cancer Trevor A. Graham (United Kingdom) - 09:45 Tumour cell plasticity and immune evasion in metastatic colorectal cancer. Eduard Batlle Gomez (Spain) - 11:45 Cutting the nerve supply to pancreatic cancer Andreas Trumpp (Germany) - 16:40 Neutrophil-driven inflammation in PDAC progression Dieter Saur (Germany) - 17:30 Exploring the therapy-associated tumour immune microenvironment across the spectrum of HCC Tom Bird (UK) - 17:45 Intermittent fasting in MASH and liver cancer Suchira Gallage (Germany) - 17:50 Metabolic drivers of cancer and obesity-related diseases Guadalupe Sabio (Spain)

Adam and Allison Podcast
Tastes like a Payday!

Adam and Allison Podcast

Play Episode Listen Later Oct 27, 2025 3:25


Jennifer swears that peanuts and candy corn taste just like a Payday bar and are addictive! So we try it for Mash it Up Monday!

All You Can Eat
Mash Tatoes EP 162

All You Can Eat

Play Episode Listen Later Oct 26, 2025 35:38


On Tap: That mystery pre-fab section, Halloween breaking news, Starbucks caters to the key crowd and a Chipotle scandal erupts.The closing tune is performed by Allison Bishop - find her at https://www.allisonbishopmusic.com/ Hosted on Acast. See acast.com/privacy for more information.

VISION ON SOUND
VISION ON SOUND EPISODE 258 - TX OCTOBER 26 2025

VISION ON SOUND

Play Episode Listen Later Oct 26, 2025 59:39


WARREN CUMMINGS takes us on a journey into some Action TV.First broadcast on FAB RADIO INTERNATIONAL at 19:00 on October 26th 2025.This week we welcome back WARREN CUMMINGS who initially joined me for a bit of a random TV viewing catch up. We start out talking briefly about our recent viewing choices of shows like THE SECRET AGENT, TAKING OVER THE ASYLUM, ALFRED HITCHCOCK PRESENTS and M*A*S*H, but our conversation then takes a sudden sharp handbrake turn as we find ourselves talking at some length about the more action-orientated TV shows, prompted by mentions of THE EQUALIZER, THE PROFESSIONALS and CALLAN: THE MOVIE, amongst others, and we end up giving some serious consideration to the wisdom or otherwise of portraying vigilantism as entertainment.I sometimes think that VISION ON SOUND works extremely well when we take a random route to a totally unexpected subject after being prompted by this simple idea we once had of talking about archive TV, and I hope you will enjoy the next hour as much as we did.PLEASE NOTE - For Copyright reasons, musical content sometimes has to be removed for the podcast edition. All the spoken word content remains (mostly) as it was in the broadcast version. Hopefully this won't spoil your enjoyment of the show.

Mixabilly.Com's Hot Roddin' 2+Nite
Hot Roddin' 2+Nite - Ep 694 - 10-25-25

Mixabilly.Com's Hot Roddin' 2+Nite

Play Episode Listen Later Oct 25, 2025 84:45


4 weeks of horror concludes with a Halloween Bash so light your Jack 'O Lantern, get out the treats, turn up YOUR media players and prepare to STOMP around to chilling & thrilling tunes that really MASH it up! https://mixabilly.com donate @ https://paypal.com/paypalme/mixabilly

The Secret Teachings
Monster Mash (10/22/25)

The Secret Teachings

Play Episode Listen Later Oct 22, 2025 120:01 Transcription Available


Monsters come in many forms and each has its own definition and interpretation. Sometimes monsters are separate from other scary creatures and other times they help categorize them. In the pre-ancient world, monsters were natural disasters and phenomena, symbolized by Titans. We actually create Titan-like gods today when we name hurricanes, and we perform appeasement rituals when we advocate for green policies and products to stop the destruction of an attack. In the ancient world monsters were outsiders, people with birth defects, people who were deformed from an accident, people who were tall or short (relatively), etc. Today we take the tall and small alike and profit from them still in the form of entertainment just as they were paraded through royal palaces in the past in Europe. In the pre-modern world, the latter ideas were maintained but monsters were shaped into theological demons, largely extracted from vegetation myths and zealous-imagination. More modern monsters have been defined by movies, ecology, and psychology. Also, from Dracula and Michael Myers to Godzilla and zombies, science can explain just as much as the supernatural classifications can. Dracula sucks “life force,” Michael is “pure evil” that cannot be killed, Godzilla is the folly of man, and zombies may be formed by drugs or fungus. Horror is such because it brings the abnormal to view, by sound, children, clowns, dolls and the general “uncanny valley.” The fear of snakes and danger of electricity certainly contributed to Medusa's ability, just as deer antlers contributed to the devil. Humans have also grown horns or tales, even in contemporary times, while some have suffered from clawed hands from ectrodactyly. Modern political and religious monsters are in abundance, too, and some are so vile they essentially suffer from clinical lycanthropy. Unable to control their emotions they transform into beasts and scream like a banshee. *The is the FREE archive, which includes advertisements. If you want an ad-free experience, you can subscribe below underneath the show description.FREE ARCHIVE (w. ads)SUBSCRIPTION ARCHIVEX / TWITTER FACEBOOKWEBSITEBuyMe-CoffeePaypal: rdgable1991@gmail.comCashApp: $rdgable EMAIL: rdgable@yahoo.com / TSTRadio@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-secret-teachings--5328407/support.

The Brülosophy Podcast
Episode 401 | Impact Mash Recirculation Has On A Cream Ale

The Brülosophy Podcast

Play Episode Listen Later Oct 21, 2025 67:44


Brülosophy merch is now available - click here to see all we have to offer! Contributor Jordan Folks joins Marshall to discuss mash recirculation as well as review the results of a fascinating xBmt on the topic. Become a Brülosophy Patron today and be rewarded for your support! | Relevant Article | Impact Continuous Recirculation Of The Mash Has On A Cream Ale xBmt

Pharma and BioTech Daily
Transformative Oncology Breakthroughs and Regulatory Shifts

Pharma and BioTech Daily

Play Episode Listen Later Oct 20, 2025 5:51


Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we'll delve into a series of remarkable advancements and strategic movements shaping the landscape of healthcare. Let's start with a recent spotlight on the European Society for Medical Oncology Congress 2025, where key clinical trial outcomes have emerged, potentially reshaping future treatment protocols.AstraZeneca made waves with its Phase 3 trial results for Imfinzi, a PD-L1 inhibitor, in high-risk non-muscle invasive bladder cancer. The findings suggest that Imfinzi stands strong against Pfizer's PD-1 candidate, Sasanlimab. This is particularly noteworthy as bladder cancer has historically had limited non-invasive treatment options. The implications for patient care are substantial, providing hope for improved management of this form of cancer and possibly influencing treatment standards.Meanwhile, Eli Lilly's Verzenio marked another success at the ESMO Congress with its overall survival win in early breast cancer cases. This victory enhances Verzenio's standing within the CDK4/6 inhibitor class, suggesting increased adoption in clinical settings. The demonstration of extended survival benefits not only strengthens Verzenio's competitive position but also contributes to setting a new standard of care in early breast cancer treatment.On the regulatory front, Sanofi encountered mixed outcomes from the European Medicines Agency's Committee for Medicinal Products for Human Use. While Rezurock was not recommended as a third-line treatment for chronic graft-versus-host disease, this decision underscores the stringent regulatory processes companies navigate despite existing market success in other regions like the U.S.In a significant move by the FDA to expedite drug approvals, nine companies including Merck KGaA and Regeneron received priority review vouchers. These vouchers allow a shortened review timeline, reflecting an ongoing trend towards accelerating drug availability to address unmet medical needs swiftly.In terms of strategic developments, EMD Serono—Merck KGaA's U.S. branch—has unveiled a major discount initiative for its IVF treatments on the TrumpRx platform. This aligns with broader efforts to make fertility treatments more accessible amidst rising demand and economic pressures.The metabolic dysfunction-associated steatohepatitis (MASH) arena is also witnessing robust interest with over $10 billion recently reported in mergers and acquisitions. This surge indicates confidence among Big Pharma players in MASH as a lucrative therapeutic field ripe for innovation and development.In response to competitive pressures and operational challenges, Kezar Life Sciences is preparing for layoffs following the FDA's decision to cancel a critical meeting related to its R&D program. This situation illustrates the volatile dynamics within biotech firms where regulatory decisions can significantly impact corporate strategies and workforce stability.Overall, these developments reflect an industry characterized by rapid innovation, strategic realignments, and an evolving regulatory framework. The implications for patient care are substantial as these scientific advancements promise enhanced treatment options across various therapeutic areas.Switching gears to scientific developments, Bristol Myers Squibb has reported promising results from early-stage trials of its EGFRxHER3 antibody-drug conjugate. Demonstrating a 55% overall response rate, this positions BMS to potentially gain a competitive edge in the ADC market—a sector valued for targeting cancer cells while minimizing side effects on healthy tissues.Strategic partnerships continue to shape industry growth and innovation. Roche has secured a deal with Hansoh Pharmaceutical worth up to $1.45 billion for global rights to an experimental ADC outside Greater China. SimilSupport the show

Adam and Allison Podcast
Choco taco meat

Adam and Allison Podcast

Play Episode Listen Later Oct 20, 2025 5:06


A bunch of taco kits were recalled because they put hot chocolate packets in them instead of taco seasoning. So we made our very own choco tacos for Mash it Up Monday!

History & Factoids about today
Oct 20th - National Jeff Day! Bela Lugosi, Snoop Dogg, Tom Petty, Jerry Orbach, Cobra Kai, MASH

History & Factoids about today

Play Episode Listen Later Oct 20, 2025 13:35 Transcription Available


National Jeff day. Entertainment from 1991. Big Foot videoed, MacArthur retruned to Philippines, Soviet pilot crashes passenger jetliner over a bet. Todays birthdays - Bela Lugosi, William Christopher, Jerry Orbach, Top Petty, Earl Hindman, William Zabka, Snoop Dogg. Ronnie Van Zant died.Intro - God did good - Dianna Corcoran    https://www.diannacorcoran.com/The Jeffrey song - The guy who sings your name over and overEmotions - Mariah CareyAnymore - Travis TrittBirthdays - In da club - 50 Cent        http://50cent.com/MASH TV themeHome Improvement TV themeDon't do me like that - Tom Perry and the HeartbreakersGin & Juice - Snoop DoggGive me 3 steps - Lynyrd SkynyrdExit - Trouble in paradise - Bohemian Rogue      https://bohemianroguemusic.com/countryundergroundradio.comHistory & Factoids about today webpage

The Bourbon Daily
The Bourbon Daily Show #3,296 – Jack Daniel's Sweet Mash

The Bourbon Daily

Play Episode Listen Later Oct 19, 2025 19:50


Steve, Darren, JP & Kyle get a taste of a special new product from Jack Daniel's. TBD music by Kevin MacLeod (incompetech.com).   Important Links: Patreon: https://www.patreon.com/theabvnetwork Our Events Page: bourbonpalooza.com Check us out at: abvnetwork.com. The ABV Barrel Shop: abvbarrelshop.com   Join the revolution by adding #ABVNetworkCrew to your profile on social media.   Steve, McNew, Justine and Katie talk about the new King of Kentucky release. TBD music by Kevin MacLeod (incompetech.com).

Why Does the Wilhelm Scream?
Him, Highest 2 Lowest, and Mash

Why Does the Wilhelm Scream?

Play Episode Listen Later Oct 18, 2025 120:41


On today's episode: three films that ask the question: yes, but at what cost? Albeit in very different ways. We're talking "Him," Spike Lee's Kurosawa re-imagining, "Highest 2 Lowest," and our first trip to the early Alts with Robert Altman's "Mash." At least one of these films was fun to watch. Support Why Does the Wilhelm Scream Keep in touch and read more at whydoesthewilhelmscream.com on instagram and threads @whydoesthewilhelmpod  Find out more about upcoming Reel House screenings, and support the next generation of film lovers, at reelhousefoundation.org and on facebook/Instagram reelhousefoundation Artwork by @_mosla_

The Gareth Cliff Show
Testosterone Trouble & Political Tantrums

The Gareth Cliff Show

Play Episode Listen Later Oct 17, 2025 175:44


17.10.25 - Gareth and Leigh-Ann kick off the weekend with laughs (and a few groans) as Leigh-Ann details her never-ending health saga. The team dives into South Africans' growing frustration with self-serving politicians, before Ben and Mash jump in to unpack whether modern society is running low on testosterone — and what that means for masculinity today. Plus, things get spicy as Ben and Producer James settle a long-standing beef live on air The Real Network

The Fantasy 40 Podcast
Week 7: M.A.S.H. Units

The Fantasy 40 Podcast

Play Episode Listen Later Oct 16, 2025 71:56


We have reached the fantasy football midpoint and injuries are piling up (this week it as the pass catchers).   Listen to the 40 and figure out how to fight on in fantasy!

Your Natural Dog with Angela Ardolino - Formerly It's A Dog's Life
117. Do No Harm: Upholding the Veterinarian's Oath with Dr. Margo Roman

Your Natural Dog with Angela Ardolino - Formerly It's A Dog's Life

Play Episode Listen Later Oct 16, 2025 37:28


On this episode of Your Natural Dog, Angela sits down with Dr. Margo Roman, a veterinarian with over 47 years in practice, to talk about what the veterinary oath really means, and what happens when vets try to speak openly about holistic or integrative pet care. Dr. Roman shares how her Massachusetts veterinary license was suspended for two years after she emailed clients about ozone and homeopathic options, which she's now appealing to the U.S. Supreme Court after losing at the state level. Angela and Dr. Roman also discuss why they believe “do no harm” requires a fuller toolbox: acupuncture, microbiome work, ozone, nutrition, herbs, and the importance of ongoing education after vet school. The conversation looks at how policies, liability fears, and funding ties can discourage open discussion of holistic pet care. They also cover the “spectrum of care” model for real-world budgets, the debate over rabies titers and vaccine exemptions, why gut health is foundational, and practical ways pet parents can stay informed and advocate for more options.Episode Recap:Angela tees up free speech, the veterinarian's oath, and why Dr. Roman's case matters to pet parents. (00:08)The Veterinarian's Oath, and how it extends beyond what's taught in school. (03:15)Dr. Roman describe the lack of options being offered to pet parents by conventional veterinarians, and they discuss the declining numbers of holistic veterinarians. (04:49)Why continuing your veterinary education, from acupuncture to microbiome science, is essential to the “do no harm” oath, and how ignoring proven alternative modalities amounts to denying care.(07:55)Angela shares her experience getting an FDA letter and the pressure to stay silent about holistic education and testimonials. (10:12)Dr. Roman shares the story of her horse with cancer, Champ, who she was told to euthanize, but instead lived for over 8 more years under her care using homeopathy, acupuncture, nutrition, and later ozone therapy. When she tried to show the university her results, they refused to look. (11:50)The pandemic, recommending ozone therapy,  and the veterinary board's response. (13:31)Introduction to “Spectrum of Care” for clients who can't afford gold-standard workups. (15:46)How corporate and government control often limits access to natural options, the vital role of the gut microbiome and the endocannabinoid system, and how mushrooms and hemp have long supported balance in both humans and animals. (17:40)Dr. Roman describes the financial and emotional toll of defending her right to practice integrative medicine, including spending over a million dollars and facing ongoing board harassment. She explains how officials dismiss modalities like acupuncture and ozone therapy without ever studying them, and calls for accountability and open-mindedness among regulators who condemn what they don't understand. (20:10)Dr. Roman argues that forcing veterinarians to vaccinate animals who are already immune or medically fragile goes against the veterinary oath, and shares her own experience with Rabies vaccination and antibody testing (22:43)Being your pet's advocate, what Dr. Roman is working on now, plus ways to support her mission (30:09)Episode Resources:Download Angela's resources & guides at AngelaArdolino.com/podcast-downloadsThe Veterinarian's OathDr. Roman's Urgent Call for Veterinarians to Uphold their Oath and her Medical Freedom For Animals Legal FundDr. Margo Roman v. Board of Registration in Veterinary Medicine, Massachusetts Supreme Judicial CourtDr. Roman's Veterinary Practice Main Street Animal Services of HopkintonFollow Dr. Roman & MASH on Twitter, Facebook,and InstagramHave a question about your pet that you want answered on the podcast? Email us at Carter@yournaturaldog.com Sign up for episode reminders and updates from Your Natural Dog with Angela ArdolinoVisit Angela Ardolino's website for more holistic pet health education: www.AngelaArdolino.comFollow Your Natural Dog on Facebook and Instagram and if you want to see what Angela is up to, follow her on Facebook or join our CBD & Holistic Pet Advice Facebook Group.

Rugby Wrap Up
The Rugby Odds: Cardiff/Hollywood, Toulouse Mash Bordeaux, Quins Big Win, Leinster v Munster. Picks

Rugby Wrap Up

Play Episode Listen Later Oct 16, 2025 28:26


Season 6 Episode 4 NEW YORK, NY – Buckle up for another wildly entertaining episode of The Rugby Odds — the show critics call "irreverent but necessary!" With its mix of sharp insight, bold opinions, and unapologetic nonsense, this panel of rugby eccentrics breaks down the week's biggest stories like no one else can.

The Matt & Jerry Show

The Matt & Jerry Show

Play Episode Listen Later Oct 16, 2025 41:00 Transcription Available


On the pod today Jeremy Wells is back and our old mate Mash joins us from the Manaia Stewart Memorial Chair. Listen as the guys talk about all things Austin, Texas!See omnystudio.com/listener for privacy information.

At First Listen
Bobby 'Boris' Pickett's "Monster Mash" (1962) - The Only Halloween Song?

At First Listen

Play Episode Listen Later Oct 16, 2025 16:33 Transcription Available


This bonus episode is a loving tribute to the greatest and one true Halloween song.  Tell us about your first listen @AtFirstListenpodcast on Instagram! Subscribe so you don't miss an episode! (NOTE: Andrew is of course referring to “Superstition” by Stevie Wonder when he says “Supernatural.” He is humiliated.)

MASH Matters
Radar's Drum Solo - MASH Matters #143

MASH Matters

Play Episode Listen Later Oct 15, 2025 44:08


Drums! Bourbon! Potterisms! This episode has EVERYTHING! Jeff & Ryan open up the mailbag to discuss a wide range of subjects, including Jeff's new headphones, Hawkeye's gray hair, Agnes Gomes, Igor's Hawaiian shirt, extreme explanations for well-known M*A*S*H anachronisms, flight simulators, prequels, and more. Plus, the return of Shoppers Casino!   Support the podcast on Patreon and buy merch at the MASH Matters store   For show notes, episodes, recipes, bios, and more visit our website.    

Healing Horses with Elisha
88: Tips for Easier Mash Prep

Healing Horses with Elisha

Play Episode Listen Later Oct 14, 2025 19:34


With winter just around the corner, I decided to offer some tips today, for preparing mash in the colder months.Stay tuned for practical tips to make soaking and preparing mash far easier- not only in winter, but throughout the year.Keep Mash Prep SimpleKeep mash prep simple by using single, whole ingredients rather than mixed commercial feeds full of synthetics and fillers. This approach supports recovery and makes year-round feeding easier.Soaking Cubes and Beet PulpAlways soak cubes or alfalfa to prevent choking and improve digestibility. Use warm water to soften them, and soak overnight when possible. It is also essential to expand the beet pulp and pellets by allowing them to soak overnight. Preventing Mold and SpoilageBeet pulp molds easily in warm barns, so never leave it for more than a day. Store soaked mash in a cool, dry spot to keep it fresh.Adding Dry Ingredients at Feeding TimeKeep dry ingredients separate until feeding. Mix the soaked portion first, then add dry ingredients right before serving to maintain freshness and nutrient quality.Preparing in AdvanceFor convenience, prepare ziplock bags with a month's worth of pre-measured dry mixes. Label each bag and then add it to the soaked mash when ready to feed.Handling Oils and Apple Cider VinegarAdd oil and apple cider vinegar at feeding time, and not in advance. Oils can go rancid if left open or exposed to heat, and vinegar is most effective when added just before feeding. It supports digestion and metabolic function and can even be offered in water if horses like the taste.When Soaking Isn't PracticalIf soaking is impractical, use dry ingredients like alfalfa pellets or bran and moisten them slightly before feeding to make the meal more palatable.Simplifying for Helpers or TravelIf you need to go away and have someone else feeding your horse, you can simplify things by providing pre-packed dry mixes. Short breaks or simplified routines will not undo your horse's progress, and you can resume full feeding once you return.Consistency Over PerfectionIf you can only prepare mash three times a week, it is still worthwhile. Consistency matters more than perfection, and horses benefit even from partial improvement. Links and resources:Connect with Elisha Edwards on her website Join my email list to be notified about new podcast releases and upcoming webinars.Free Webinar Masterclass: Four Steps to Solving Equine Metabolic Syndrome NaturallyRegister for my self-paced course, Resolving Equine Metabolic Syndrome Naturally.Mentioned in this episode:Learn the 4 Steps to Resolving Metabolic Syndrome NaturallySign up for the FREE masterclass today!Masterclass

Garage Logic
MISCHKE: Misch-Mash

Garage Logic

Play Episode Listen Later Oct 8, 2025 52:42


A little bit of everything in this one: A guest cancels, calls are made, souls are crushed, revelations are unveiled, coffee is brewed, Neil Diamond spills the beans, Turkish men in the 60s unload on hapless American housewives. All that and a gator in the tub to boot. A misch-mash indeed.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Baseball Tonight with Buster Olney
Sigh of Relief: Aaron Judge Gives the Yankees Life; Mariners Mash; Loaded Day of Division Series Games

Baseball Tonight with Buster Olney

Play Episode Listen Later Oct 8, 2025 47:42


Eric Hosmer and Buster discuss the Yankees wining game three with help from an Aaron Judge homer, how to handle a pitch that far inside, Judge's double-take a the dugout camera, the suspect managing in the playoffs, if the Mariners and Brewers can wrap up their series, and why the Dodgers are looking better than every other team. Later, Sarah Langs plays The Numbers Game.  CALL THE SHOW: 406-404-8460 EMAIL THE SHOW: BleacherTweets@gmail.com REACH OUT ON X: #BLEACHERTWEETS 14:36 Eric Hosmer 39:07 Sarah Langs 40:16 Bleacher Tweets Learn more about your ad choices. Visit podcastchoices.com/adchoices

Fantasy Focus Baseball
Sigh of Relief: Aaron Judge Gives the Yankees Life; Mariners Mash; Loaded Day of Division Series Games

Fantasy Focus Baseball

Play Episode Listen Later Oct 8, 2025 47:42


Eric Hosmer and Buster discuss the Yankees wining game three with help from an Aaron Judge homer, how to handle a pitch that far inside, Judge's double-take a the dugout camera, the suspect managing in the playoffs, if the Mariners and Brewers can wrap up their series, and why the Dodgers are looking better than every other team. Later, Sarah Langs plays The Numbers Game.  CALL THE SHOW: 406-404-8460 EMAIL THE SHOW: BleacherTweets@gmail.com REACH OUT ON X: #BLEACHERTWEETS 14:36 Eric Hosmer 39:07 Sarah Langs 40:16 Bleacher Tweets Learn more about your ad choices. Visit podcastchoices.com/adchoices

A Corporate Time with Tom and Dan
ACT - "Meshy Mash" (Wednesday 10-8-25)

A Corporate Time with Tom and Dan

Play Episode Listen Later Oct 8, 2025 55:06


The Mischke Roadshow
Misch-Mash

The Mischke Roadshow

Play Episode Listen Later Oct 8, 2025 52:42


A little bit of everything in this one: A guest cancels, calls are made, souls are crushed, revelations are unveiled, coffee is brewed, Neil Diamond spills the beans, Turkish men in the 60s unload on hapless American housewives. All that and a gator in the tub to boot. A misch-mash indeed.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Diabetes Core Update
Special Edition_ MASH Part 1 - Screening

Diabetes Core Update

Play Episode Listen Later Oct 8, 2025 20:16


In this special series on Metabolic-Dysfunction Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-associated steatohepatitis (MASH) our host, Dr. Neil Skolnik will discuss Epidemiology, Importance, Screening and treatment of MASH. This special episode is supported by an independent educational grant from Boehringer Ingelheim. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Jay Shubrook, D.O., Professor and Diabetologist in the Department of Clinical Sciences and Community Health At Touro University California College of Osteopathic Medicine Selected references: Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association. Diabetes Care 2025;48(7):1057–1082  

MASH Matters
Allan Katz Returns! - MASH Matters #142

MASH Matters

Play Episode Listen Later Oct 1, 2025 47:03


Jeff & Ryan welcome writer/director/producer/actor Allan Katz back for his second appearance on MASH Matters! This time around, the boys take a deep dive into the world of writing. We discuss Allan's process for writing for established characters, rewriting scripts from other writers, working with difficult performers (*cough* Jackie Gleason), the reason he left M*A*S*H after one season, why Larry Linville decided to depart the series, and other jocularity.   Support the podcast on Patreon and buy merch at the MASH Matters store   For show notes, episodes, recipes, bios, and more visit our website.  

The Learning Leader Show With Ryan Hawk
654: Jake Tapper - The Most Important Leadership Skill, Handling Criticism, Chasing Your Curiosity, Understanding Tradeoffs, Responding to Rejection, and Being So Good They Can't Ignore You

The Learning Leader Show With Ryan Hawk

Play Episode Listen Later Sep 21, 2025 63:44


Go to www.LearningLeader.com for full show notes This is brought to you by Insight Global. If you need to hire 1 person, hire a team of people, or transform your business through Talent or Technical Services, Insight Global's team of 30,000 people around the world have the hustle and grit to deliver. www.InsightGlobal.com/LearningLeader The Learning Leader Show with Ryan Hawk Guest: Jake Tapper is an award-winning broadcaster and chief Washington correspondent, currently anchoring The Lead with Jake Tapper every day on CNN. He's also the #1 New York Times best-selling author of 7 books, including The Outpost (which was later made into a movie), Original Sin, and most recently Race Against Terror. Notes: Be So Good They Can't Ignore You. Jake: I'm in control of how hard I work. It is our responsibility to work so hard that we become the obvious choice for the job or the promotion. Be So Good They Can't Ignore You. "I had to be so good that even though maybe on a broadcasting level I wouldn't be the number one pick... they had to give it to me." The one leadership skill that is massively important to develop… Don't insulate yourself with “yes” people. You have to have truth tellers in your life. Who are your foxhole friends? Who are the people who are willing and able to tell you the truth? Who are the ones who love you and care about you enough to let you know when you've messed up? Those people are gold. We all need them. Rejection: Dr. Seuss was rejected by 47 publishers. Rejection is part of life. You have to stay in the game for a chance to win it. Keep going. And nobody will give you a job to be nice. What value do you bring to a company? How will you make your boss's life better? You get hired to solve a problem, not because someone wants to be nice. Pinned tweet since 2017 – "To see what is in front of one's nose needs a constant struggle." -- George Orwell. A reminder to see obvious truths being obscured by spin or wishful thinking. "You Can Always Tell Them No" - Ted Koppel's crucial advice to young Jake about maintaining journalistic integrity and not compromising values for opportunities. This became a career-defining principle that Jake still follows 20 years later. The Jar Jar Binks Theory of Leadership - Successful leaders often remove critics from their inner circle, creating dangerous echo chambers. "Great people often achieve as much as they can to the point that they are able to remove from their inner circle anyone who tells them they're being an asshole or making a wrong decision." Constructive vs. Destructive Criticism - Jake learned to distinguish between useful feedback and personal attacks: "Very few of my critics are people that I actually care what they think... folks who understand I'm just trying to be a good faith operative here." Curiosity as Career Driver - Deep curiosity drove Jake from reading microfiche about MASH as a kid to investigating complex stories as an adult: "I find something interesting and I wanna find out everything I can about it." Rejection as Constant Reality - Even at his career peak, Jake faces daily rejection: "I get rejected every day... it doesn't matter that I've had New York Times bestsellers before... it's part of life." Humility Enables Learning - Accepting expertise gaps allows growth: "Having the humility to accept that I am not an expert on any particular thing... I'm a journalist, which means I try to be an expert on whatever I'm covering at that moment." Leadership Lessons From Powerful People The Inner Circle Problem: Leaders systematically remove critics until surrounded only by yes-people, creating dangerous blind spots. Jake witnessed this pattern with Joe Biden (surrounded by aides and family who weren't honest about his declining acuity) and across industries. The Solution: Intentionally maintain truth-tellers in your inner circle who care about you personally but will challenge you professionally. Creating Truth-Telling Environments: Jake encourages healthy disagreement with executive producers, acknowledges power imbalances that make criticism harder for junior staff, and creates indirect channels for feedback ("some people on the staff think..."). The Criticism Paradox: Public leaders face constant harsh criticism, making them naturally defensive. Understanding this context helps leaders distinguish between constructive feedback that improves performance versus personal attacks that serve no purpose. Following Curiosity Despite Opposition Jake's major works were all advised against by professionals: The Outpost (no military expertise) The Atlantic story of freeing a wrongly imprisoned man Biden book (started the day after the election, despite uncertainty) Key Insight: "Every single one of them, people were telling me not to do it... It's been following my curiosities even when people told me I'm not interested in that." The Hard Work Advantage: Jake couldn't compete on appearance or natural broadcasting ability, so he outworked everyone: broke stories constantly, used blogs when he couldn't get on air, and made himself impossible to ignore through sheer output. Dealing with Rejection Expect constant rejection even at a career peak Don't take rejection personally unless there's constructive feedback Use rejection as data, not judgment of worth Keep creating regardless of immediate acceptance The Wave Metaphor: Like Tom Hanks in Cast Away, timing the waves - "every code can be cracked" if you persist and find the right timing. Key Elements for Writers: Strong structure: "Act one, chase your hero up a tree. Act two: throw rocks at your hero. Act three, get your hero out of the tree." Good editor who pushes back - be willing to "kill your darlings" Life Philosophy The Acceleration Mindset: At 56, Jake is speeding up output: "I don't know how much longer I have this window where people are paying attention... relevance is ephemeral... when it leaves, it looks fucking brutal." For Young People: "So much of life is rejection... You cannot stop it... don't take it personally." Focus on developing skills and delivering value: "Nobody will give you a job to be nice... They'll do it because you have something they want." Time Sacrifice Awareness: Success requires acknowledging costs: "What I cried about is the stuff I missed that I wasn't there for because I was chasing a story or on assignment." Time Stamps: 02:46 Jake's Dedication to Influential Figures 05:05 Hot Mic Moment in Alaska 06:59 Preparing for Big Interviews & When to Follow Up 09:01 Dealing with Criticism 12:07 The Story Behind Jake's Pinned Tweet 13:48 Race Against Terror: The New Book 18:29 Balancing Multiple Roles 20:47 Chasing Your Own Curiosity  23:58 Sacrifices for Career Success 29:00 The Importance of Humility in Leadership 31:08 Surrounding Yourself with Truth Tellers 34:18 Healthy Tension in Team Dynamics 37:15 Understanding the Pressure on Public Figures 40:09 Empathy in Leadership 45:17 Balancing Career and Family 49:00 Advice for Aspiring Journalists and Writers 52:01 The Reality of Rejection and Hard Work 57:26 The Importance of Structure and Editing in Writing 01:01:16 End of the Podcast Club