Podcasts about network meta analysis

In dieser Folge spreche ich mit Florent Crépin, Geschäftsführer von Neurolite. Er stellt eine Depressions-Behandlung vor, die ohne Medikamente auskommt.Links :LinkedIn Instagram NeuroliteYoutube Instagram FlowFacebook FlowÜBER DEPRESSIONDepressionen.ch Stiftung Deutsche DepressionshilfeREFERENZENBarker et al. Non-invasive magnetic stimulation of human motor cortex. Lancet. 1985 May. Zur PublikationRush et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006 Nov. Zur PublikationFregni et al. Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders. Int J Neuropsychopharmacol. 2021 Apr. Zur PublikationWoodham et al. Home-based transcranial direct current stimulation treatment for major depressive disorder: a fully remote phase 2 randomized sham-controlled trial. Nat Med. 2025 Jan. Zur PublikationCipriani et al. Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis. Focus (Am Psychiatr Publ). 2018 Oct. Zur PublikationSaelens et al. Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials. Neuropsychopharmacology. 2024 Dec. Zur PublikationGriffiths et al. Self-Administered “Flow” Transcranial Direct Current Stimulation (tDCS) Depression Treatment in a Crisis Resolution & Home Treatment (CRT) Service: Functioning, and Health-Related Quality of Life Outcomes. Open Journal of Psychiatry. 2024 Nov. Zur PublikationTomonaga et al. The economic burden of depression in Switzerland. Pharmacoeconomics. 2013 Mar. Zur PublikationDeutsche S3-Leitlinie und Nationale VersorgungsLeitlinie (NVL)  Kurzfassung – Lass mir Feedback da :)Hat dir die Folge gefallen? Ich würde mich über eine 5-Sterne-Bewertung sehr freuen! :)Webseite: https://www.psychologieunddenn.ch/Whatsapp-Gruppe (offen für alle): https://chat.whatsapp.com/JBcjpAaIaSeCRxmQMQWGXuMöchtest du Werbung schalten oder mit mir zusammenarbeiten. Dann schau hier vorbei.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Safety and Efficacy of Different Stent Strategies in Percutaneous Coronary Intervention: A Network Meta-Analysis

In this research-packed episode, Dr. Scott Watier and Tommy Welling analyze groundbreaking findings from a network meta-analysis that evaluates the most effective combinations of fasting styles and exercise types for weight loss. The study's surprising conclusion reveals that alternate-day fasting paired with moderate-intensity continuous training significantly outperforms other approaches, scoring an impressive 88% effectiveness for weight loss and 93% for fat mass reduction. The hosts break down why this combination works so well—explaining how it enhances metabolic flexibility, improves insulin sensitivity, and promotes sustainable fat oxidation—while debunking common misconceptions about needing high-intensity workouts for optimal results. They provide practical guidance for implementing these evidence-based strategies, emphasizing that consistent moderate exercise (like zone 2 training) combined with strategic longer fasting windows delivers superior outcomes with better long-term adherence than traditional approaches. Whether you're just starting your fasting journey or looking to optimize your current routine, this episode offers clear, actionable insights backed by the latest scientific research. Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting! Resources and Downloads: SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! - December 2024 FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! SLEEP GUIDE DIRECT DOWNLOAD DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! Partner Links: Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Our Community: Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Links: https://storage.googleapis.com/msgsndr/6JyvZbS9DGozfkVmE452/media/67bf3a92ed60db2f5765f5e3.pdf

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Novel Therapies to Reduce Rehospitalization Risk in Worsening Heart Failure: Systematic Review and Network Meta-Analysis.

In this episode, Dr. Valentin Fuster discusses a comprehensive network meta-analysis published in JACC, which evaluates the optimal strategy for complete revascularization in patients with STEMI and multi-vessel disease. The study concludes that both immediate and staged complete revascularization improve patient outcomes over partial revascularization, with no significant advantage between angiographic and functional guidance, suggesting that angiographic guidance alone may be sufficient in clinical practice.

Dr. Emily Eshleman discusses the #4 article of 2023, “Management of de Quervain Tenosynovitis,” which was originally published in JAMA Network Open in October 2023. Dr. Jeremy Schroeder serves as the series host. Dr. Eshleman is a member of the AMSSM Top Articles Subcommittee, and this episode is part of an ongoing mini journal club series highlighting each of the Top Articles in Sports Medicine from 2023, as selected for the 2024 AMSSM Annual Meeting. Management of de Quervain Tenosynovitis: A Systematic Review and Network Meta-Analysis https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2811119

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-399 Overview: In this episode, we look at a new study showing increased probability of survival for patients with Alzheimer disease (AD) who take donepezil and memantine together. We review current treatments for AD and address common hesitations in prescribing dual pharmacotherapy, providing vital insights for primary care clinicians. Episode resource links: Yaghmaei, E., Lu, H., Ehwerhemuepha, L. et al. Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimer's disease patients.Commun Med 4, 99 (2024). https://doi.org/10.1038/s43856-024-00527-6 Guo J, Wang Z, Liu R, Huang Y, Zhang N, Zhang R. Memantine, Donepezil, or Combination Therapy-What is the best therapy for Alzheimer's Disease? A Network Meta-Analysis. Brain Behav. 2020 Nov;10(11):e01831. doi: 10.1002/brb3.1831. Epub 2020 Sep 10. PMID: 32914577; PMCID: PMC7667299. Guest: Jillian Joseph, MPAS, PA-C Music Credit: Richard Onorato Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-399 Overview: In this episode, we look at a new study showing increased probability of survival for patients with Alzheimer disease (AD) who take donepezil and memantine together. We review current treatments for AD and address common hesitations in prescribing dual pharmacotherapy, providing vital insights for primary care clinicians. Episode resource links: Yaghmaei, E., Lu, H., Ehwerhemuepha, L. et al. Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimer's disease patients.Commun Med 4, 99 (2024). https://doi.org/10.1038/s43856-024-00527-6 Guo J, Wang Z, Liu R, Huang Y, Zhang N, Zhang R. Memantine, Donepezil, or Combination Therapy-What is the best therapy for Alzheimer's Disease? A Network Meta-Analysis. Brain Behav. 2020 Nov;10(11):e01831. doi: 10.1002/brb3.1831. Epub 2020 Sep 10. PMID: 32914577; PMCID: PMC7667299. Guest: Jillian Joseph, MPAS, PA-C Music Credit: Richard Onorato Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief

When Jonathan White, a Massachusetts-based estate planning attorney and former college hockey player, felt the pressure of his expanding practice and the pandemic's toll on his well-being, he returned to a familiar ally: exercise. On this episode of Great Practice, Great Life, Steve and Jonathan's conversation dives into Jonathan's path from grappling with the anxiety of hiring his first employee to re-embracing fitness routines that brought balance back into his life. We unearth the moments where he chose health over more billable hours, demonstrating that prioritizing personal well-being is necessary for sustained professional success. Steve recounts his fitness odyssey that began during the lockdowns of COVID-19, transforming an overloaded work schedule into a 209-week streak of Peloton workouts. Jonathan and Steve dissect the trade-offs between potential billable hours and physical and mental health benefits. We connect the dots between smaller fitness goals and bigger professional achievements, outlining how mental fortitude developed through exercise can positively ripple through every aspect of life. Jonathan's anecdotes underscore how structured exercise routines influenced significant business decisions, like shedding less rewarding parts of his practice to focus on what matters. We wrap up the conversation by exploring the broader implications of exercise in combating depression and anxiety, the power of gratitude journaling, and the essential role of setting and achieving big goals. Join us for an episode that reveals how integrating physical fitness can elevate your professional and personal life. In this episode, you will hear: Jonathan White's path from college hockey player to estate planning attorney The impact of COVID-19 on Jonathan's well-being The role of exercise in regaining balance How structured exercise routines influenced significant business decisions The trade-offs between billable hours and the benefits of physical and mental health The correlation between physical fitness and professional success, including increased income and improved decision-making Some practical tips on goal setting, consistency in exercise, and leveraging physical fitness for personal and professional growth The broader implications of exercise on combating depression, anxiety, and maintaining long-term mental health Follow and Review: We'd love for you to follow us if you haven't yet. Click that purple '+' in the top right corner of your Apple Podcasts app. We'd love it even more if you could drop a review or 5-star rating over on Apple Podcasts. Simply select “Ratings and Reviews” and “Write a Review” then a quick line with your favorite part of the episode. It only takes a second and it helps spread the word about the podcast. If there's a topic you would like us to cover on an upcoming episode, please email us at steve.riley@atticusadvantage.com. Supporting Resources: Practice Growth Program®: atticusadvantage.com/what-we-do/coaching-growth-programs/pgp Dominate Your Market®: atticusadvantage.com/what-we-do/dominate-your-market The Path to a Great Practice & Great Life: atticusadvantage.mykajabi.com/the-path-to-a-great-practice-and-great-life-workshop-landing?_gl=1*ri47aj*_gcl_au*NjU1OTUyOTI2LjE3MTQwNjA2MTM.*_ga*MTg2MTUyMzY5NS4xNjY2MDIxMDMz*_ga_QWWLP5WT2C*MTcxODM5NTUzOC4zMzAuMS4xNzE4Mzk1NTQyLjU2LjAuMA My Great Life™ Planner: atticusadvantage.com/product/my-great-life-planner Great Practice. Great Life.® by Atticus® – 048: Overcoming the Challenges of Making Your First Hire with Victor Medina and Johnathan White: atticusadvantage.com/episode048 Jordan & White, LLC: jordanwhitellc.com The Five Minute Journal: a.co/d/0hzRmu6 Effect of Exercise for Depression: Systematic Review and Network Meta-Analysis of Randomized Controlled Trials: www.bmj.com/content/384/bmj-2023-075847 Is Exercise More Effective than Medication for Depression and Anxiety: www.medicalnewstoday.com/articles/is-exercise-more-effective-than-medication-for-depression-and-anxiety Effectiveness of Physical Exercise in the Treatment of Depression in Older Adults as an Alternative to Antidepressant Drugs in Primary Care: bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-018-1982-6 Episode Credits If you like this podcast and are thinking of creating your own, consider talking to my producer, Emerald City Productions. They helped me grow and produce the podcast you are listening to right now. Find out more at https://emeraldcitypro.com Let them know we sent you.

Cardiogenic shock accounts for up to 5% of acute heart failure presentations and around 14–16% of patients reported in cardiac intensive care datasets. It complicates up to 15% of all myocardial infarctions and is the leading cause of death post-infarction. Using pharmacological agents alone may increase left ventricular afterload and myocardial oxygen demand, resulting in complications. Thus, mechanical circulatory support (MCS) devices have emerged as important therapeutic options. As evidence remains uncertain, MCS selection depends on clinician preference and local availability.An updated systematic review and meta-analysis of high-quality RCTs and propensity score-matched studies (PSMs) was performed to compare the outcomes of MCS devices with no MCS and each other and investigate which MCS is the most effective in reducing mortality.To learn more about the findings of this study listen to this podcast.

Le Mini Temps Psy du Militanpsy ! Un petit temps accordé à une grande connaissance de soi

Heute habe ich die liebe Caro Baumgartner zu Gast, Caro ist Ärztin und hat sich auf Präventiv- und Ernährungsmedizin spezialisiert. Wir haben gemeinsam über das aktuelle Trend Thema „Longevity“ gesprochen was für Caro „Prävention“ bedeutet. Weiterhin haben wir vor allem darüber gesprochen, warum die kardiovaskuläre Gesundheit so wichtig ist warum Bluthochdruck eine wichtige Gesundheitsmessgröße ist. Wie misst man den Blutdruck richtig? Welche gesundheitlichen Folgen gibt es, wenn Bluthochdruck unbehandelt bleibt, welche Symptome können auf Bluthochdruck hinweisen, wie kann er behandelt werden und wie wirken sich Ernährung, Sport und Bewegung aus? Hat dir die Episode gefallen oder hörst du meinen Podcast regelmäßig? Hinterlasse mir doch gerne eine Bewertung bei Apple Podcasts oder Spotify, damit würdest du mir eine riesige Freude bereiten und meinen Podcast und mich sehr unterstützen. Hast du Fragen oder Feedback? Schreib uns gern! Hier kannst du mir gerne jederzeit schreiben: ✉️ Instagram: https://www.instagram.com/fit__laura/ ✉️ Mail: kontakt@fitlaura.de Meine App: https://www.fitlaura.de/membership/? Meine Bücher: https://www.fitlaura.de/produkt-kategorie/kochen/ Hier findest du Caro: https://www.instagram.com/doc.caro.fitmed/ Ihre Praxis: BOdygraph München Meine Podcast Episode zum Thema Blutzuckerspiegel: https://podcasts.apple.com/de/podcast/blutzucker-wie-der-blutzuckerspiegel-unsere-gesundheit/id1468139783?i=1000632228296 Genannte Studien und Links: Blutdruckmessgeräte: https://www.hochdruckliga.de/betroffene/blutdruckmessgeraete Edwards JJ, Deenmamode AHP, Griffiths M, et al Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials British Journal of Sports Medicine 2023;57:1317-1326. Vinci, P., Di Girolamo, F. G., Panizon, E., Tosoni, L. M., Cerrato, C., Pellicori, F., Altamura, N., Pirulli, A., Zaccari, M., Biasinutto, C., Roni, C., Fiotti, N., Schincariol, P., Mangogna, A., & Biolo, G. (2023). Lipoprotein(a) as a Risk Factor for Cardiovascular Diseases: Pathophysiology and Treatment Perspectives. International journal of environmental research and public health, 20(18), 6721. https://doi.org/10.3390/ijerph20186721 Yang et al, 2023, Systolic Blood Pressure Control Targets to Prevent Major Cardiovascular Events and Death in Patients With Type 2 Diabetes: A Systematic Review and Network Meta-Analysis, https://pubmed.ncbi.nlm.nih.gov/37254768/

Recent research indicates that those who suffer from AxSpA may have some hope in protecting against events of Uveitis! Dr. Katie Bechman, first author Incidence of Uveitis in Patients With Axial Spondylarthritis Treated With Biologics or Targeted Synthetics: A Systematic Review and Network Meta-Analysis, explains her team's research findings and how they came to this exciting conclusion! 

Dr. Scott Paradise concludes the countdown and reviews the No. 1 article of 2022 on this episode of the Top Sports Medicine Articles podcast, which is hosted by Dr. Jeremy Schroeder. The top-rated article examines, “Comparative Efficacy of Nonoperative Treatments for Greater Trochanteric Pain Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials,” which was originally published in the Clinical Journal of Sport Medicine in July 2022. Dr. Paradise is a member of the AMSSM Top Articles Subcommittee, and this episode is part of an ongoing mini journal club series highlighting each of the Top Articles in Sports Medicine from 2022, as selected for the 2023 AMSSM Annual Meeting in Phoenix, AZ. Thanks to everyone who helped determine the top sports medicine articles of 2022, and find out what the top articles of 2023 will be during the AMSSM Annual Meeting in Baltimore, MD. Comparative Efficacy of Nonoperative Treatments for Greater Trochanteric Pain Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials DOI: doi.org/10.1097/JSM.0000000000000924

Dr. John Fleetham chats with Dr. Bijan Teja and Dr. Nicholas Bosch about their article, "Effectiveness of Fludrocortisone Plus Hydrocortisone Versus Hydrocortisone Alone in Septic Shock: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials." 

We already knew probiotics improve leaky gut, but this study shows just how game-changing probiotics might be for leaky gut improvement.  Tune in and let me know what you think!  Watch/Read Next… What is Leaky Gut: https://drruscio.com/what-is-leaky-gut/  Symptoms of Leaky Gut: https://drruscio.com/symptoms-of-leaky-gut/  How to Use Leaky Gut Supplements to Target Inflammation: https://drruscio.com/leakygut-supplements/  Your Guide for How to Use Probiotics for Leaky Gut: https://drruscio.com/probiotics-for-leaky-gut/  Should You Get a Leaky Gut Test? https://drruscio.com/leaky-gut-syndrome-test/  Create Your Personalized Leaky Gut Diet Plan: https://drruscio.com/leaky-gut-diet-plan/    Timestamps 00:00 Intro  00:46 Symptoms of leaky gut 02:39 The game-changing leaky gut study  06:05 Serum zonulin & testing  08:30 Probiotics improve SYMPTOMS 10:34 Our Probiotic Protocol   Featured Studies  Effect of a Multistrain Probiotic on Leaky Gut in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study: https://pubmed.ncbi.nlm.nih.gov/36007493/   Efficacy of Probiotics for Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis: https://pubmed.ncbi.nlm.nih.gov/35433498/   Clinical effects and gut microbiota changes of using probiotics, prebiotics or synbiotics in inflammatory bowel disease: a systematic review and meta-analysis: https://pubmed.ncbi.nlm.nih.gov/33555375/  Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults: https://pubmed.ncbi.nlm.nih.gov/32005532/  Comparative effectiveness of probiotic strains for the treatment of pediatric atopic dermatitis: A systematic review and network meta-analysis: https://pubmed.ncbi.nlm.nih.gov/32524647/  Role of Probiotics in Patients with Allergic Rhinitis: A Systematic Review of Systematic Reviews: https://pubmed.ncbi.nlm.nih.gov/36405454/  Effects of Microecological Regulators on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/36904103/  Probiotics as an effective therapeutic approach in alleviating depression symptoms: an umbrella meta-analysis: https://pubmed.ncbi.nlm.nih.gov/35348020/  Probiotic supplementation improved cognitive function in cognitively impaired and healthy older adults: a systematic review of recent trials: https://pubmed.ncbi.nlm.nih.gov/36529793/     Get the Latest Updates Facebook - https://www.facebook.com/DrRusciodc Instagram - https://www.instagram.com/drrusciodc/ Pinterest - https://www.pinterest.com/drmichaelrusciodc    DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g  *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.

A variety of drugs are used for people with panic disorder and the effects of these were brought together in November 2023 in a Cochrane review and network meta-analysis by Giuseppe Guaiana from Western University in St Thomas Canada and a large group of international authors. Here's Giuseppe to tell us about the problem, and whether these drug treatments are helpful.

A variety of drugs are used for people with panic disorder and the effects of these were brought together in November 2023 in a Cochrane review and network meta-analysis by Giuseppe Guaiana from Western University in St Thomas Canada and a large group of international authors. Here's Giuseppe to tell us about the problem, and whether these drug treatments are helpful.

New research doesn't just tell us that probiotics improve leaky gut, candida, and IBS, it tells us how.  Join me to unpack the exciting findings behind probiotics for leaky gut, candida, and IBS, and a protocol you can use at home to help find relief.  And if you have any additional questions you would like answered in the future, let me know in the comments!   Watch/Read Next… Create a Leaky Gut Diet Plan: https://drruscio.com/?p=56263  How to Spot Leaky Gut: https://www.youtube.com/watch?v=7QER7XXJ5CM&t=3s What's the Strongest Candida Killer?: https://drruscio.com/strongest-candida-killer/  What is IBS? https://drruscio.com/what-is-ibs  How to Relieve the Symptoms of IBS Attacks: https://drruscio.com/stop-the-struggle-how-to-relieve-the-symptoms-of-ibs-attacks/    Timestamps 00:00 Intro  01:58 Impressive vaginal candida effectiveness  04:51 Gastrointestinal candida findings  05:56 Remarkable leaky gut results  10:04 Positive impacts to IBS symptoms  18:04 Where probiotics made no difference  19:58 Do different probiotics have different benefits?  22:46 The most effective probiotics for IBS 23:40 Research-based probiotic protocol    Featured Studies  Comparing the Effect of Probiotic and Fluconazole on Treatment and Recurrence of Vulvovaginal Candidiasis: a Triple-Blinded Randomized Controlled Trial: https://pubmed.ncbi.nlm.nih.gov/36198994/ Probiotics Prevent Candida Colonization and Invasive Fungal Sepsis in Preterm Neonates: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/27793494/ Candida albicans- The Virulence Factors and Clinical Manifestations of Infection: https://pubmed.ncbi.nlm.nih.gov/33499276/ Effect of a Multistrain Probiotic on Leaky Gut in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study: https://pubmed.ncbi.nlm.nih.gov/36007493/ Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials: https://pubmed.ncbi.nlm.nih.gov/37168869/ An 8-Week Course of Bifidobacterium longum 35624® Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome: https://pubmed.ncbi.nlm.nih.gov/37702965/ Efficacy and dose response of Lactiplantibacillus plantarum in diarrhea-predominant irritable bowel syndrome: https://pubmed.ncbi.nlm.nih.gov/37576702/ Efficacy and safety of Bifidobacterium quadruple viable tablets combined with mosapride citrate in the treatment of constipation in China: a systematic review and meta-analysis: https://pubmed.ncbi.nlm.nih.gov/37464298/ Evaluation of the effects of the FODMAP diet and probiotics on irritable bowel syndrome (IBS) symptoms, quality of life and depression in women with IBS: https://pubmed.ncbi.nlm.nih.gov/37430435/ The Efficacy and Safety of Single-Strain Probiotic Formulations Containing Bifidobacterium lactis or Bacillus coagulans in Adult Patients with Irritable Bowel Syndrome-A Randomized Double-Blind Placebo-Controlled Three-Arm Interventional Trial: https://pubmed.ncbi.nlm.nih.gov/37510953/ Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis: https://pubmed.ncbi.nlm.nih.gov/37686889/    Get the Latest Updates Facebook - https://www.facebook.com/DrRusciodc Instagram - https://www.instagram.com/drrusciodc/ Pinterest - https://www.pinterest.com/drmichaelrusciodc    DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g  *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video. Click here to apply for our YouTube Channel & Podcast Manager position. https://drruscio.bamboohr.com/careers/71?source=aWQ9MjE%3D 

In this episode, we explore whether the olanzapine–samidorphan combination helps with psychosis while halting weight gain. We also look into the cost vs benefit of the combination as well as the metabolic side effects. Faculty: James Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 51 Comparative Efficacy, Safety, and Acceptability of Pimavanserin and Other Atypical Antipsychotics for Parkinson's Disease Psychosis: Systematic Review and Network Meta-Analysis

This episode explores the controversial role of pimavanserin in treating psychosis in Parkinson's disease. How does it compare with quetiapine or clozapine? Sneak peek: All of these medications are effective, yet none distinctly surpasses the others. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 51 Comparative Efficacy, Safety, and Acceptability of Pimavanserin and Other Atypical Antipsychotics for Parkinson's Disease Psychosis: Systematic Review and Network Meta-Analysis

Commentary by Dr. Valentin Fuster

Join us for a super speedy summary of the new network meta-analysis exploring the efficacy and safety of different medications for osteoporosis. Learn more and become a member at https://drjournalclub.com/Earn CEU and take one of our courses, like our Critical Evaluation of the Literature Bootcamp: https://drjournalclub.com/critical-evaluation-bootcamp/Händel MN, Cardoso I, von Bülow C, Rohde JF, Ussing A, Nielsen SM, Christensen R, Body JJ, Brandi ML, Diez-Perez A, Hadji P, Javaid MK, Lems WF, Nogues X, Roux C, Minisola S, Kurth A, Thomas T, Prieto-Alhambra D, Ferrari SL, Langdahl B, Abrahamsen B. Fracture risk reduction and safety by osteoporosis treatment compared with placebo or active comparator in postmenopausal women: systematic review, network meta-analysis, and meta-regression analysis of randomised clinical trials. BMJ. 2023 May 2;381:e068033. doi: 10.1136/bmj-2021-068033. PMID: 37130601; PMCID: PMC10152340.Learn more and become a member at www.DrJournalClub.comCheck out our complete offerings of NANCEAC-approved Continuing Education Courses.

ESC23 LBT- OCT vs. IVUS vs. Angiography Guidance - a Real-Time Updated Network Meta-Analysis

Pouch expert Dr Laura Raffals joins Dr Sunanda Kane to deep-dive into patient care after J-pouch surgery. Topics include pouchitis, Crohn's of the pouch, pelvic floor dysfunction, and pregnancy. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/984009). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Ulcerative Colitis https://emedicine.medscape.com/article/183084-overview Ileal Pouch-anal Anastomosis https://emedicine.medscape.com/article/1892231-overview Northwestern Medicine Feinberg School of Medicine Faculty Profiles https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=29442 Microbiome Analysis of Mucosal Ileoanal Pouch in Ulcerative Colitis Patients Revealed Impairment of the Pouches Immunometabolites https://pubmed.ncbi.nlm.nih.gov/34831464/ University of Chicago, Biological Sciences Division Faculty https://biologicalsciences.uchicago.edu/faculty/eugene-b-chang-md Mayo Clinic Department of Gastroenterology and Hepatology Biographies https://www.mayoclinic.org/biographies/camilleri-michael-m-d/bio-20054405 Crohn Disease https://emedicine.medscape.com/article/172940-overview Complications Related to J-pouch Surgery https://pubmed.ncbi.nlm.nih.gov/30846911/ A Systematic Review: The Management and Outcomes of Ileal Pouch Strictures https://pubmed.ncbi.nlm.nih.gov/29155985/ Pre-pouch Ileitis Is Associated With Development of Crohn's Disease-like Complications and Pouch Failure https://pubmed.ncbi.nlm.nih.gov/33300546/ Primary Sclerosing Cholangitis https://emedicine.medscape.com/article/187724-overview Pathologic Features and Clinical Significance of "Backwash" Ileitis in Ulcerative Colitis https://pubmed.ncbi.nlm.nih.gov/16224214/ Efficacy and Safety of Biologics and Small Molecule Drugs for Patients With Moderate-to-severe Ulcerative Colitis: A Systematic Review and Network Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/34856198/ Anastomotic Leak After Ileal Pouch-Anal Anastomosis https://pubmed.ncbi.nlm.nih.gov/34853564/ Inflammatory Bowel Disease https://emedicine.medscape.com/article/179037-overview Ileostomy https://pubmed.ncbi.nlm.nih.gov/30085545/ Pelvic Floor Dysfunction https://pubmed.ncbi.nlm.nih.gov/32644672/ The London Classification: Improving Characterization and Classification of Anorectal Function With Anorectal Manometry https://pubmed.ncbi.nlm.nih.gov/32935278/ Defining Normal Pouch Function in Patients With Ileal Pouch-Anal Anastomosis: A Pilot Study https://pubmed.ncbi.nlm.nih.gov/35274320/ MR Defecography Review https://pubmed.ncbi.nlm.nih.gov/31544226/ Pouch Function and Gastrointestinal Complications During Pregnancy After Ileal Pouch-anal Anastomosis https://pubmed.ncbi.nlm.nih.gov/20608799/

Visit pointofcaremedicine.com to see the templates, pearls, literature, and other resources discussed in this episode. Our mission is to create accessible and easy-to-use digital resources that help healthcare professionals tackle common clinical presentations at the point of care, without getting bogged down by unnecessary details or trivia. Show Notes: 00:00:15 - Introduction and Terminology 00:01:51 - Beta Blockers 00:02:47 - ACE/ARB/ARNI 00:04:30 - MRA's 00:05:28 - SGLT2i's 00:06:12 - Nitrates and Hydralazine 00:08:41 - Loop Diuretics 00:09:25 - Initiating and Titrating GDMT 00:11:18 - Barriers and Other Considerations 00:13:44 - Resources for Use at the Point of Care Other Resources and References: GDMT for Everyone – https://www.gdmt.org/HFrEF.php Table of all the Sacubitril/Valsartan Trials Published to Date (2023) - https://twitter.com/jaycvance/status/1660732176999108623 An elegant graphic showing how the hazard ratios with confidence intervals for all-cause mortality improve based on adding on each extra GDMT medication; brought to my attention by a tweet from Dr. Scott Cameron - ⁠https://twitter.com/2Scottish/status/1556798319996932096⁠ Heart Failure with Reduced Ejection Fraction: A Review (JAMA, 2020) - https://pubmed.ncbi.nlm.nih.gov/32749493/ A Systematic Review and Network Meta-Analysis of Pharmacological Treatment of Heart Failure With Reduced Ejection Fraction (JACC, 2022) - ⁠https://www.jacc.org/doi/full/10.1016/j.jchf.2021.09.004

How do you help patients with soft stool that won't move through manage idiopathic constipation? Join Drs Lin Chang and Anthony Lembo as they discuss nuanced decision-making around treating IBS subtypes. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/987261). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Irritable Bowel Syndrome (IBS) https://emedicine.medscape.com/article/180389-overview Sigmoid Afferent Mechanisms in Patients With Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/9201070/ Peripheral Opioids for Functional GI Disease: A Reappraisal https://pubmed.ncbi.nlm.nih.gov/16699267/ Dietary Concerns and Patient-Focused Care in Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/36398143/ The Epidemiology of Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/24523597/ Diagnosis and Treatment of Irritable Bowel Syndrome: A Review https://pubmed.ncbi.nlm.nih.gov/33651094/ Review Article: An Integrated Approach to the Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/10429736/ AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea https://pubmed.ncbi.nlm.nih.gov/35738725/ Psyllium Reduces Inulin-Induced Colonic Gas Production in IBS: MRI and in Vitro Fermentation Studies https://pubmed.ncbi.nlm.nih.gov/34353864/ Efficacy of Secretagogues in Patients With Irritable Bowel Syndrome With Constipation: Systematic Review and Network Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/30144426/

Expert: Andrea Boutros, IRCCS Ospedale Policlinico San Martino, Genoa, Italy

This month for the May 2023 episode of the RCEM Learning Podcast we've got two New in EM segments which shoulder relocation technique is best and the use of TXA in haemoptysis. We then speak with Tessa Davis of Don't Forget The Bubbles fame and her top tips for delivering teaching online. We then speak to Evan Bayton about the RCEM Coat of Arms and what on earth it all means, and then end with New Online. If you'd like to email us, please feel free to do so here. (02:02) New in EM - Which shoulder relocation technique is best? A Systematic Review with Pairwise and Network Meta-Analysis of Closed Reduction Methods for Anterior Shoulder Dislocation (Gonai et al., 2023) (19:01) Tessa Davis - Delivering Teaching Online Tessa Davis Twitter Tessa Davis' Homepage (34:02) New in EM - IV vs. Nebulised TXA for haemoptysis Nebulized vs IV Tranexamic Acid for Hemoptysis: A Pilot Randomized Controlled Trial (Gopinath et al., 2023) (45:53) Evan Bayton - The RCEM Coat of Arms The RCEM Coat of Arms (01:02:34) New Online – new articles on RCEMLearning for your CPD #PEM23 - Nikki Abela and Liz Herrieven Curriculum Cup - Major Trauma - RCEMLearning Necrotising Fasciitis - Amy Armstrong

In this episode of the Award-winning PRS Journal Club Podcast, 2023 Resident Ambassadors to the PRS Editorial Board – Rami Kantar, Yoshi Toyoda, and Ronnie Shammas- and special guest Nicholas Haddock, MD, discuss the following articles from the April 2023 issue: “Immediate Breast Cancer Reconstruction with or without Dermal Matrix or Synthetic Mesh Support: A Review and Network Meta-Analysis” by Murphy, O'Donnell, Ryan, et al. Read the article for FREE: https://bit.ly/ImmediateBreastCancerRecon Special guest Nicholas Haddock, MD, is a microsurgeon who completed his residency training at NYU, followed by a microsurgery fellowship at the University of Pennsylvania. He is an Associate Professor in the Department of Plastic Surgery and the Department of Orthopedic Surgery at UT Southwestern Medical Center and is a pioneer in microsurgical breast reconstruction and efficiency in breast reconstructive surgery. He also serves as an Associate Editor for the Plastic and Reconstructive Surgery Journal. READ the articles discussed in this podcast as well as free related content from the archives: https://bit.ly/JCApril23Collection

There's no paucity of studies for biologic therapies used to treat psoriatic disease, but the number of head-to-head trials comparing these agents is limited. Enter network meta-analysis, a statistical methodology that has emerged over the past few years to compare medication. Philip Mease, MD, a clinical professor at the University of Washington School of Medicine and director of rheumatology research at the Swedish Medical Center in Seattle, and Dr. Wolf-Henning Boehncke, chair of the division of dermatology and venereology at Geneva University Hospitals, Switzerland, and full professor at the Department of Pathology and Immunology at Geneva University, discuss the use of network meta-analyses and potential pitfalls in choosing biologic therapies for patients with psoriasis and psoriatic arthritis in this episode of Practical Dermatology: The Podcast.

Theme: Critical Care.Participants: Dr Alex Yartsev (intensivist at Westmead Hospital), Dr Mark Salter (emergency physician at Westmead Hospital), Maddy Jegatheeswaran (intensive care Fellow at Westmead Hospital), Gladis Kabil (registered nurse at Westmead Hospital), Kristian Adams, Pramod Chandru, Caroline Tyers, Amanda De Silva, Shreyas Iyer, and Samoda Wilegoda. Discussion:Sud, S., Friedrich, J. O., Adhikari, N. K. J., Fan, E., Ferguson, N. D., Guyatt, G., & Meade, M. O. (2021). Comparative Effectiveness of Protective Ventilation Strategies for Moderate and Severe Acute Respiratory Distress Syndrome. A Network Meta-Analysis. American journal of respiratory and critical care medicine, 203(11), 1366–1377. https://doi.org/10.1164/rccm.202008-3039OC. Presenter: Maddy Jegatheeswaran intensive care Fellow at Westmead Hospital.Music/Sound Effects: Blue Sweater by RYYZN | https://soundcloud.com/ryyzn, Music promoted by https://www.free-stock-music.com, Creative Commons Attribution 3.0 Unported License, https://creativecommons.org/licenses/by/3.0/deed.en_US. Good Day by Ikson | https://youtube.com/ikson, Music promoted by https://www.free-stock-music.com. Slipz (audio logo) by tubebackr | https://soundcloud.com/tubebackr, Music promoted by https://www.free-stock-music.com. Disclaimer:Please be advised that the individual views and opinions expressed in this recording strive to improve clinical practice, are our own, and do not represent the views of any organization or affiliated body. Therapies discussed are general and should not be a substitute for an individualized assessment from a medical professional.Thank you for listening!Please send us an email to let us know what you thought.You can contact us at westmeadedjournalclub@gmail.com.You can also follow us on Facebook, Instagram, and Twitter!See you next time!~

In this episode, we discuss a systematic review and network analysis that compares 11 medications for treating severe agitation in the emergency department. Which medications have been shown to work best?  Faculty: Jim Phelps, M.D.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 39 Rapid Tranquilization of the Agitated Patient in the Emergency Department: A Systematic Review and Network Meta-Analysis

Renal Replacement Therapy (RRT) is a complex treatment for patients both in and out of the ICU environment.  There are multiple different modes, machines and functions and this episode is about addressing the confusion and answering all your questions in relation to RRT. Below are the links to articles referred to throughout the podcast Systematic review and meta-analysis of renal replacement therapy modalities for acute kidney injury in the intensive care unit   https://eds.p.ebscohost.com/eds/viewarticle/render?data=dGJyMPPp44rp2%2fdV0%2bnjisfk5Ie46a9Ir66yUbWk63nn5Kx94um%2bUa2orkewprBKnqy4SbSws1Get8s%2b8ujfhvHX4Yzn5eyB4rOvUbSnrkmyr7dKpOnnfLvbsEvfp7RRtaOufeKtq0y2qbJF4KzjS6vasU7iqLd7sKy3ed%2b28H3i3%2fE%2b6tfsf7vb7D7i2Lt94unjhO6c8nnls79mpNfsVdGmtlCxr7JMr6e1S66ntUq1nOSH8OPfjLvc84Tq6uOQ8gAA&vid=0&sid=e23a1697-0ed7-4834-b6e3-d36d29c269aa@redis     Comparing Renal Replacement Therapy Modalities in Critically ill Patients with Acute Kidney Injury:  A Systematic Review and Network Meta-Analysis   https://eds.p.ebscohost.com/eds/viewarticle/render?data=dGJyMPPp44rp2%2fdV0%2bnjisfk5Ie46a9Ir66yUbWk63nn5Kx94um%2bUa2orkewprBKnqy4SbSws1Get8s%2b8ujfhvHX4Yzn5eyB4rOvUbSnrkmyr7dKpOnnfLvbsEvfp7RRtaOufeKtq0y2qbJF4KzjS6vasU7iqLd7sKy3ed%2b28H3i3%2fE%2b6tfsf7vb7D7i2Lt94unih%2bic8nnls79mpNfsVePa8Xzt4KxPsq7gS7CqsXmvq7BMr6%2fjULCn4H6z265%2br6yyS6%2fc5D7k5fCF3%2bq7fvPi6ozj7vIA&vid=1&sid=e23a1697-0ed7-4834-b6e3-d36d29c269aa@redis   Effect of sustained low efficient dialysis versus continuous renal replacement therapy on renal recovery after acute kidney injury in the intensive care unit   https://eds.p.ebscohost.com/eds/viewarticle/render?data=dGJyMPPp44rp2%2fdV0%2bnjisfk5Ie46a9Ir66yUbWk63nn5Kx94um%2bUa2orkewprBKnqy4SbSws1Get8s%2b8ujfhvHX4Yzn5eyB4rOvUbSnrkmyr7dKpOnnfLvbsEvfp7RRtaOufeKtq0y2qbJF4KzjS6vasU7iqLd7sKy3ed%2b28H3i3%2fE%2b6tfsf7vb7D7i2LuF4tmkjN%2fdu1nMnN%2bGu6i2SbCutlCvnOSH8OPfjLvc84Tq6uOQ8gAA&vid=5&sid=e23a1697-0ed7-4834-b6e3-d36d29c269aa@redis

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Drs. Jose Dianti and Ewan Goligher. They discuss their recent 2022 publication in the Blue Journal about the association of PEEP and Lung Recruitment Selection Strategies with Mortality in Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-Analysis.

Drs Hartzler and Jazrawi discuss Transosseous Equivalent Suture Bridge Arthroscopic Rotator Cuff Repair in Combination with Late Postoperative Mobilization Yields Optimal Outcomes and Retear Rate: A Network Meta-Analysis of Randomized Controlled Trials

Drs Tucker, Arner, Dekker, and Spiker discuss 2021 Year-End Recap featuring Award-Winning Papers: (1)"Platelet-Rich Plasma in Patients with Partial-Thickness Rotator Cuff Tears or Tendinopathy Leads to Significantly Improved Short-Term Pain Relief and Function Compared With Corticosteroid Injection: A Double-Blinded Randomized Controlled Trial" which was authored by lead author Cory Kwong and senior author Ian Lo, and originally published in the February 2021 issue. (2) "CAM Osteochondroplasty for Femoroacetabular Impingement Increases Microinstability in Deep Flexion: A Cadaveric Study" which was authored by lead author Geoffrey Ng and senior author Jonathan Jeffers, and originally published in the January 2021 issue. (3) "Pain Management Strategies After Anter Cruciate Ligamet Reconstruction: A Systematic Review with Network Meta-Analysis" which was authored by lead author Marti Davey and senior author Kirk Campbell, and originally published in the April 2021 issue. (4) "Development and Internal Validation of Supervised Machine Learning Algorithms for Predicting Clinically Significant Functional Improvement in a Mixed Population of Primary Hip Arthroscopy" which was authored by lead author Kyle Kunze and senior author Shane Nho, and originally published in the May 2021 issue.

Rheumatology Network interviewed Terence Rooney, MD, to discuss the findings of a Network Meta-Analysis that examined the efficacy of guselkumab (TREMFYA) for skin clearance and joint improvements in patients with psoriatic arthritis.

Cetamina Subcutânea, evidencias e comparativos para o tratamento de Depressão resistente. Este é um podcast para médicos sob responsabilidade do Dr. Tiago Gil, médico anestesista CRMSP 157384 RQE 64871 A medicina é uma ciência que está em evolução e este podcast não deve ser utilizado como guia terapêutico. Esse episodio foi gravado como verdade até setembro de 2021 Referências bibliográficas Cavenaghi VB, da Costa LP, Lacerda ALT, Hirata ES, Miguel EC, Fraguas R. Subcutaneous Ketamine in Depression: A Systematic Review. Front Psychiatry. 2021;12:513068. Published 2021 May 28. doi:10.3389/fpsyt.2021.513068 Memon, R.I., Naveed, S., Faquih, A.E. et al. Effectiveness and Safety of Ketamine for Unipolar Depression: a Systematic Review. Psychiatr Q 91, 1147–1192 (2020). https://doi.org/10.1007/s11126-020-09830-6 Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, Leucht S, Ruhe HG, Turner EH, Higgins JPT, Egger M, Takeshima N, Hayasaka Y, Imai H, Shinohara K, Tajika A, Ioannidis JPA, Geddes JR. Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis. Focus (Am Psychiatr Publ). 2018 Oct;16(4):420-429. doi: 10.1176/appi.focus.16407. Epub 2018 Oct 18. PMID: 32021580; PMCID: PMC6996085. 1. da Costa JP de OM, Bisol LW, Souza FG de M e. Which are the demographic and clinical characteristics of patients who respond to subcutaneous esketamine? Journal of Psychopharmacology. August 2021. doi:10.1177/02698811211035392 Swainson, J., McGirr, A., Blier, P., Brietzke, E., Richard-Devantoy, S., Ravindran, N., Blier, J., Beaulieu, S., Frey, B. N., Kennedy, S. H., McIntyre, R. S., Milev, R. V., Parikh, S. V., Schaffer, A., Taylor, V. H., Tourjman, V., van Ameringen, M., Yatham, L. N., Ravindran, A. V., & Lam, R. W. (2021). The Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Recommendations for the Use of Racemic Ketamine in Adults with Major Depressive Disorder: Recommandations Du Groupe De Travail Du Réseau Canadien Pour Les Traitements De L'humeur Et De L'anxiété (Canmat) Concernant L'utilisation De La Kétamine Racémique Chez Les Adultes Souffrant De Trouble Dépressif Majeur. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 66(2), 113–125. https://doi.org/10.1177/0706743720970860 https://www.dropbox.com/s/83kh7q1pqgchx22/Manual_Tratamento-Depressao_Ketamin_RF.pdf Parecer CREMESP 202957 http://www.cremesp.org.br/?siteAcao=Pareceres&dif=s&ficha=1&id=18241&tipo=PARECER&orgao=%20Conselho%20Regional%20de%20Medicina%20do%20Estado%20de%20S%E3o%20Paulo&numero=202957&situacao=&data=13-05-2021#anc_integra

Stroke and TBI Recovery with Dr. Robert Teasell MD: Part II Noggins And Neurons Facebook Group: CLICK HERE or scan below! TEASELL: ...second of all, try and develop ways in which we can move things forward. You know? Not necessarily get to the you know, I say research is always about trying to get to the truth, and we're far from it and our piece, hopefully, will get us a little closer to it, but it clearly isn't going to be it. But I do think, you know, I think we all agree that we're kind of at a point where we're stuck, you know, and stroke rehab, there doesn't seem to be a lot of movement forward clinically, you know, we've gotten really good at standardized care and even that's starting to be eroded, you know what I mean, in some jurisdictions? And I think it's time for us to really think about what do we pivot to next? Right? What do we add onto that to make it better, get people excited about stroke rehab again and sort of end that erosion of funding that is occurring in some centers and encourage more funding in other centers? EPISODE SUMMARY: This episode of NOGGINS & NEURONS: Stroke and TBI Recovery Simplified is Part II of our conversation with Dr. Robert Teasell and Marcus Saikaley of the Evidence-Based Review of Stroke Rehabilitation (EBRSR). In this episode we learn about: Brain primers – what they are and the best ways to use them The vast number of randomized controlled trials on brain priming interventions that work: mirror therapy (75), bilateral arm training (66), virtual reality (99), EMG biofeedback (66) What the words can, may and may not mean when interpreting research and how these terms are used in the EBRSR Academic training, certifications, trainings and guidelines for implementing adjunct therapies in practice The EBRSR spinoff projects: Spinal Cord Injury Evidence (SCIRE) – there are two components: The spinal cord professional aspect for rehab professionals (similar to the EBRSR) Spinal cord community – video information for patients Evidence-Based Review of Acquired Brain Injury (ERABI) – focus on cognition, mental health and community re-integration challenges following brain injury Less evidence available compared to stroke Research challenges due to the cognitive deficits experienced by brain injured people Interventions that work for stroke recovery are not always translatable to Traumatic Brain Injury – the injuries are not the same stroke lesions tend to be more focal compared with TBI The CORE Program consists of many research projects The future, network meta-analysis as a tool for the future. Compares multiple treatments against each other with: direct evidence and can estimate indirect evidence (can make estimates for comparative effectiveness of two interventions which might not be compared in the literature) The best interventions according to the Network Meta-Analysis are.... Modified Constraint Induced Movement Therapy. Developed by yours truly, Pete Levine, and his colleague Dr. Steven Page Functional e-stim Theta burst stimulation Motor imagery Bilateral Arm Therapy Research shows that primers work better than facilitators, but therapists seem to like facilitators more. Now it's time to start using the treatments that work. Adjunct treatments, standardized treatments, the future and improved care Wondering how to help therapists use the research on interventions that work to maximize recovery 85% of interventions that work are adjunct treatments we don't use very often – we need to take advantage of them, especially the cheap ones. We hope you feel as inspired as we do after listening to this episode on interventions that work and other resources. As always, we want to hear your top takeaways! LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION: Evidence-Based Review of Stroke Rehabilitation -  Evidence-Based Review of Moderate-to-Severe Acquired Brain Injury -  Spinal Cord Injury Research Evidence -  Collaboration of Rehabilitation Research Evidence Collaboration of Rehabilitation Research Evidence twitter Dr. Teasell's Google Scholar Page  Questions and Comments about the podcast? NogginsAndNeurons@gmail.com NogginsAndNeurons: The Website Noggins And Neurons Facebook Group Donate to The Noggins And Neurons Podcast with your PayPal app: Pete's blog, book, Stronger After Stroke, and talks. Blog Book: Stronger After Stroke, 3rd edition Talks: Sept. 28, 11:10 AM.Recovery from Brain Injury: The Nexus of Neuroscience and Neurorehab. American College of Rehabilitation Medicine. *Virtual  October 28, 8:00 PM (ET) The Neuroplastic Model of Spasticity Reduction *Virtual.    Deb's OT Resources: Deb's OT resources The OT's Guide to Mirror Therapy Tri-Fold Mirror (US address only) Occupational Therapy Intervention: Scavenger Hunt Visual Scanning for Adults REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you're passionate about stroke recovery and have information or a story you believe will help others, we'd love help you share it on the show. Complete the guest request form below and let's see if we're a good fit!   Guest Request Form   MUSIC: “Soft Inspiration” by Scott Holmes/Scott Holmes Music/scottholmesmusic.com

A meta-analysis of antidepressant doses and responses finds no evidence of improved outcomes with higher doses, just more side effects. However, this conclusion is based on fixed-dose comparison studies, which do not mirror the way we practice. Here we'll compare the lack of evidence for a dose-response relationship to your clinical practice. Faculty:  Jim Phelps Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about Premium Membership here Earn 0.5 CMEs: Quick Take Vol. 24 In Search of a Dose-Response Relationship in SSRIs—A Systematic Review, Meta-Analysis, and Network Meta-Analysis

Featuring Dr. Philip Sloane, Dr. Mallory Brown This podcast will spotlight articles from the July, 2021 issue of JAMDA - the Journal of the Society for Post-Acute and Long-Term Care Medicine. Dr. Sloane is a family physician and geriatrician with a master's degree in public health. He is the Elizabeth and Oscar Goodwin distinguished professor of Family Medicine and Geriatrics at the University of North Carolina at Chapel Hill, and Co-director for the program on aging, disability, and long-term care, at the Cecil G Sheps Center for Health Services Research   Dr. Brown is also a family physician and geriatrician at University of North Carolina, where she is an associate professor of family medicine and director of the residency training program.   References: Richards, K., PhD, RN; et. al., "Nighttime Agitation in Persons with Dementia as a Manifestation of Restless Legs Syndrome", JAMDA, July/2021. den Brok, M., MD.; et. al., "Antihypertensive Medication Classes and the Risk of Dementia: A Systematic Review and Network Meta-Analysis", JAMDA, July/2021. Kang, B., PhD., et. al., "Rejection of Care and Aggression among Older Veterans with Dementia: The Influence of Background Factors and Interpersonal Triggers", JAMDA, July/2021. Jia, F., PhD; et. al., "Subjective Cognitive Decline, Cognitive Reserve Indicators, and the Incidence of Dementia", JAMDA, July/2021. Recorded: July 28, 2021 Available Credit: 0.25 CMD-Clinical

***JOIN THE FASTING RAMP-UP CHALLENGE THAT STARTS JULY 25, 2021! WE SAW INCREDIBLE RESULTS FROM OUR JUNE CHALLENGE, SO DON'T MISS THIS CHANCE TO JOIN US! LEARN MORE AND REGISTER BELOW.  www.thefastingforlife.com/live   In this episode, Dr. Scott and Tommy discuss a recent literature review looking at the very popular idea that eating smaller, more frequent meals is the best way to raise your metabolic rate. They go over actionable takeaways from the data, as well as how fasting can play a powerful role in optimizing your results.   Schwingshackl L, Nitschke K, Zähringer J, et al. Impact of Meal Frequency on Anthropometric Outcomes: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Adv Nutr. 2020;11(5):1108-1122. doi:10.1093/advances/nmaa056   Have a question you'd like us to answer? Click here to send it to us or leave us a voicemail we can play on the show!   Show Transcript: www.thefastingforlife.com/blog   If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it makes a difference in helping bring you the best original content each week. We also really enjoy reading them!   Sign up for the Fasting For Life newsletter at www.thefastingforlife.com   Join the Community on Facebook!   Follow Fasting For Life: www.facebook.com/thefastingforlife www.instagram.com/thefastingforlife

Article discussed in today's episode:Comparative Effectiveness of Protective Ventilation Strategies for Moderate and Severe Acute Respiratory Distress Syndrome. A Network Meta-Analysis

In this week's Talk Evidence, Joe Ross, BMJ editor and professor at Yale again joins Helen Macdonald to talk about emerging evidence on Covid-19. They also welcome to the podcast Juan Franco, family physician in Buenos Aires, and professor at the Instituto Universitario Hospital Italiano, and new editor-in-chief of BMJ Evidence Based Medicine. This week, the team bring you updates on; Post-covid syndrome in individuals admitted to hospital with covid-19 - how are people with long covid faring. Finally published research from Scandinavia on the risk of thrombotic events after administration of the Oxford-AstraZeneca vaccine - how big is the risk, and what does that mean for the overall benefit of that vaccine. How difficult the UK population found it to understand and stick to the rules with our test, trace and isolate system - and some of the questions that this raises for this public health approach. and finally, research that showed non-drug interventions are as good as pharmaceuticals at treating people with depression and dementia - and the holistic effect that alleviating depression can have. Full reading list Ayoubkhani, Daniel, Kamlesh Khunti, Vahé Nafilyan, Thomas Maddox, Ben Humberstone, Ian Diamond, and Amitava Banerjee. 2021. “Post-Covid Syndrome in Individuals Admitted to Hospital with Covid-19: Retrospective Cohort Study.” BMJ 372 (March): n693. https://www.bmj.com/content/372/bmj.n693 Pottegård, Anton, Lars Christian Lund, Øystein Karlstad, Jesper Dahl, Morten Andersen, Jesper Hallas, Øjvind Lidegaard, et al. 2021. “Arterial Events, Venous Thromboembolism, Thrombocytopenia, and Bleeding after Vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: Population Based Cohort Study.” BMJ 373 (May): n1114. https://www.bmj.com/content/373/bmj.n1114 Smith, Louise E., Henry W. W. Potts, Richard Amlôt, Nicola T. Fear, Susan Michie, and G. James Rubin. 2021. “Adherence to the Test, Trace, and Isolate System in the UK: Results from 37 Nationally Representative Surveys.” BMJ 372 (March): n608. https://www.bmj.com/content/372/bmj.n608 Watt, Jennifer A., Zahra Goodarzi, Areti Angeliki Veroniki, Vera Nincic, Paul A. Khan, Marco Ghassemi, Yonda Lai, et al. 2021. “Comparative Efficacy of Interventions for Reducing Symptoms of Depression in People with Dementia: Systematic Review and Network Meta-Analysis.” BMJ 372 (March): n532. https://www.bmj.com/content/372/bmj.n532

In this week's Talk Evidence, Joe Ross, BMJ editor and professor at Yale again joins Helen Macdonald to talk about emerging evidence on Covid-19. They also welcome to the podcast Juan Franco, family physician in Buenos Aires, and professor at the Instituto Universitario Hospital Italiano, and new editor-in-chief of BMJ Evidence Based Medicine. This week, the team bring you updates on; Post-covid syndrome in individuals admitted to hospital with covid-19 - how are people with long covid faring. Finally published research from Scandinavia on the risk of thrombotic events after administration of the Oxford-AstraZeneca vaccine - how big is the risk, and what does that mean for the overall benefit of that vaccine. How difficult the UK population found it to understand and stick to the rules with our test, trace and isolate system - and some of the questions that this raises for this public health approach. and finally, research that showed non-drug interventions are as good as pharmaceuticals at treating people with depression and dementia - and the holistic effect that alleviating depression can have. Full reading list Ayoubkhani, Daniel, Kamlesh Khunti, Vahé Nafilyan, Thomas Maddox, Ben Humberstone, Ian Diamond, and Amitava Banerjee. 2021. “Post-Covid Syndrome in Individuals Admitted to Hospital with Covid-19: Retrospective Cohort Study.” BMJ 372 (March): n693. https://www.bmj.com/content/372/bmj.n693 Pottegård, Anton, Lars Christian Lund, Øystein Karlstad, Jesper Dahl, Morten Andersen, Jesper Hallas, Øjvind Lidegaard, et al. 2021. “Arterial Events, Venous Thromboembolism, Thrombocytopenia, and Bleeding after Vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: Population Based Cohort Study.” BMJ 373 (May): n1114. https://www.bmj.com/content/373/bmj.n1114 Smith, Louise E., Henry W. W. Potts, Richard Amlôt, Nicola T. Fear, Susan Michie, and G. James Rubin. 2021. “Adherence to the Test, Trace, and Isolate System in the UK: Results from 37 Nationally Representative Surveys.” BMJ 372 (March): n608. https://www.bmj.com/content/372/bmj.n608 Watt, Jennifer A., Zahra Goodarzi, Areti Angeliki Veroniki, Vera Nincic, Paul A. Khan, Marco Ghassemi, Yonda Lai, et al. 2021. “Comparative Efficacy of Interventions for Reducing Symptoms of Depression in People with Dementia: Systematic Review and Network Meta-Analysis.” BMJ 372 (March): n532. https://www.bmj.com/content/372/bmj.n532

In schizophrenia, which antipsychotics cause the most weight gain, cholesterol, or glucose increases? Which antipsychotics cause the least? Although a new study may not change your list much, there are some surprises in this episode.  Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about Premium Membership here Earn 0.5 CME: Quick Take Vol. 21 Comparative Effects of 18 Antipsychotics on Metabolic Function in Patients With Schizophrenia, Predictors of Metabolic Dysregulation, and Association With Psychopathology: A Systematic Review and Network Meta-Analysis

For today's episode we will be reviewing three articles about asthma from the May-June 2019 issue of Allergy Watch: Reslizumab Compared with Benralizumab in Patients with Eosinophilic Asthma: A Systematic Literature Review and Network Meta-Analysis. https://www.ncbi.nlm.nih.gov/pubmed/30217529 Anti-IL-5 treatments in patients with severe asthma by blood eosinophil thresholds: Indirect treatment comparison. https://www.ncbi.nlm.nih.gov/pubmed/30205189 Indirect Treatment Comparisons and Biologics https://www.ncbi.nlm.nih.gov/pubmed/30612667 Endotypes of severe allergic asthma patients who clinically benefit from anti?IgE therapy https://www.ncbi.nlm.nih.gov/pubmed/30107059/ Budesonide/formoterol maintenance and reliever therapy in adolescent patients with asthma https://www.ncbi.nlm.nih.gov/pubmed/29301922 Please give us feedback, corrections, and suggestions! Email feedback to: allergytalk@acaai.org ACAAI is presenting this podcast for educational purposes only. It is not medical advice or intended to replace the judgment of a licensed physician. The College is not responsible for any claims related to procedures, professionals, products or methods discussed in the podcast, and it does not approve or endorse any products, professionals, services or methods that might be referenced. Today's speakers have the following disclosures: Dr. Lee was on an advisory board for Teva. Dr. Kalangara has received consulting fees from Astra Zenica. Dr. Fineman  Speaker: AstraZenca, Boehringer Ingelheim, Shire Research: Aimmune, DBV, Shire, Regeneron.

Andrea Cipriani is NIHR Research Professor at the Department of Psychiatry, University of Oxford and Honorary Consultant Psychiatrist at the NHS Foundation Trust in Oxford. His main interest in psychiatry is evidence-based mental health and his research focuses on the evaluation of treatments in psychiatry, mainly major depression, bipolar disorder and schizophrenia. Dr Cipriani is author of 267 peer reviewed scientific publications (Scopus), mainly systematic reviews, meta-analyses and randomised controlled trials in psychopharmacology, however in the past few years he has also been investigating relevant issues in epidemiological psychiatry and public health, like patterns of drug consumption, risk of serious adverse events (most of all suicide and deliberate self harm) and implementation of treatment guidelines. Being interested in the methodology of evidence synthesis, Dr Cipriani has now a specific focus on network meta-analysis and individual patient data meta-analysis, trying to assess the validity, breadth, structure and interpretation of these statistical approaches to better inform the mental healthcare decision-making process. He is currently Editor in Chief of Evidence-Based Mental Health (ebmh.bmj.com) and also on the Editorial Board of the Lancet Psychiatry, the Australian and New Zealand Journal of Psychiatry and the Cochrane Collaboration for Depression, Anxiety and Neurosis