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When wildfire threatens neighbourhoods with closely-spaced homes, what determines whether flames leap from one structure to the next? The FSRI research team - Rebekah Schrader, Joseph Willi, Daniel Gorham and Gavin Horn - joins us to unveil their experimental series that methodically dissects the pathways through which fire spreads between buildings.The team walks us through their massive outdoor experimental setup, where they created controlled compartment fires and measured their impact on adjacent walls and windows at various separation distances. They discovered that even non-combustible exterior cladding like fiber cement board won't necessarily protect a home when the underlying sheathing is combustible—especially at close distances where heat fluxes reach a staggering 75-125 kW/m².Windows emerge as perhaps the most vulnerable component, with their research revealing dramatic differences in performance between glass types. Double-pane tempered glass significantly outperforms plain glass configurations, but the surprising finding was how much window frame materials matter. In one experiment, vinyl frames completely failed while the glass was still intact, causing entire window assemblies to drop from the wall.Another aspect of their research are the measurements of the heat transfer through intact windows. Using specialized measurements, they found that significant radiant heat penetrates even unbroken windows, potentially igniting curtains or furniture inside before the window itself fails. Low-emissivity coatings proved remarkably effective at reducing this heat transfer.This research offers crucial insights for homeowners, fire safety engineers, and policymakers working to create more resilient communities. The findings extend beyond wildland fire applications, providing valuable data for urban fire safety engineering across multiple contexts.Find the research papers at:https://onlinelibrary.wiley.com/doi/10.1002/fam.3278https://link.springer.com/article/10.1007/s10694-024-01685-8https://link.springer.com/article/10.1007/s10694-024-01656-zAnd additional resources at:https://fsri.org/research-update/journal-article-reports-heat-transfer-through-different-window-constructionshttps://fsri.org/research-update/journal-article-investigates-role-residential-siding-materials-spread-exterior----The Fire Science Show is produced by the Fire Science Media in collaboration with OFR Consultants. Thank you to the podcast sponsor for their continuous support towards our mission.
Man kann es nicht anders sagen: US-Präsident Donald Trump stürzt die Weltwirtschaft mit seinen Zöllen ins Chaos. Das primäre Ziel ist klar: US-Präsident Donald Trump will Chinas Aufstieg stoppen und belegt vor allem Importe von dort mit brachialen Zöllen. Auch wenn einige Produkte ausgenommen sind, gilt in der Spitze ein Einfuhrzoll von sagenhaften 145 Prozent. »Wir werden uns nicht von anderen Ländern als Geisel nehmen lassen, insbesondere nicht von feindlichen Handelsnationen wie China«, teilte Trump mit. In der aktuellen Folge von »Trumps Amerika« spricht Host Juan Moreno mit Bernhard Zand, Korrespondent des SPIEGEL in New York und davor viele Jahre in China. Für Zand ist keineswegs ausgemacht, wer diesen Handelskrieg gewinnen wird: »Die USA standen bis vor Kurzem wirtschaftlich glänzend da. China hatte Probleme. Aber die Chinesen bereiten sich auf diese Situation seit gut zehn Jahren vor und wissen ziemlich genau, wie sie darauf reagieren können.« Und noch eine andere Gefahr besteht. Sollte es den USA gelingen, die Chinesen wirklich wirtschaftlich zu isolieren, wonach es derzeit nicht aussieht, dürfte das die Wahrscheinlichkeit eines militärischen Konflikts mit Taiwan deutlich erhöhen. Dann wäre der Handelskrieg nur ein Vorspiel zu einem echten bewaffneten Konflikt, erklärt Zand.+++ Alle Infos zu unseren Werbepartnern finden Sie hier. Die SPIEGEL-Gruppe ist nicht für den Inhalt dieser Seite verantwortlich. +++ Den SPIEGEL-WhatsApp-Kanal finden Sie hier. Alle SPIEGEL Podcasts finden Sie hier. Mehr Hintergründe zum Thema erhalten Sie mit SPIEGEL+. Entdecken Sie die digitale Welt des SPIEGEL, unter spiegel.de/abonnieren finden Sie das passende Angebot. Informationen zu unserer Datenschutzerklärung.
In this powerful episode of The Coachable Podcast, Tori Gordon sits down with Dr. Sam Zand, founder of Anywhere Clinic and a thought leader in the mental health space. This deep conversation dives into the evolving landscape of mental health, including the groundbreaking role of AI therapy, the importance of self-reflection and shadow work, and the importance of integrating mental health care into daily life. Dr. Zand shares insights on healing, emotional regulation, sexual health, and the integration of technology into psychiatric care, all while emphasizing the importance of self-acceptance and connection in mental well-being.Key Topics:The Power of AI Therapy in Mental Health:Dr. Zand introduces AI-assisted therapy as a transformative tool for self-regulation and emotional well-being.Learn about how AI therapy functions as an interactive, self-guided journal that provides real-time support and guidance.Benefits of having an accessible "pocket therapist" to check in with, especially during moments of emotional distress.Societal Health and Mental Wellness:Why societal health is struggling and the tools and strategies needed to protect our mental well-being in the digital age.How technology can support mental health if used correctly, without overtaking our human connection to nature and spirituality.The Role of Shadow Work in Mental Health:Exploring the unconscious parts of ourselves—shame, guilt, and unresolved trauma—that influence our daily lives and decisions.The importance of looking at our shadow self and how it impacts our emotional reactions and behavior patterns.Practical tips on integrating the shadow self and cultivating self-acceptance to create a balanced and aligned life.The Intersection of Sexual Health and Emotional Well-being:A new approach to understanding sexual dysphoria and ego-dystonic sexual expression.Breaking down barriers and eliminating shame around sexual expression, and exploring the concept of somatic sex vs. cognitive sex.The importance of finding balance and intention in our relationships and sexual lives.Reintegration in Mental Health Recovery:The significance of reintegration into life after experiencing a reset or recovery process.How isolation can be detrimental and the importance of returning to triggers and stressors with new tools and awareness.Dr. Zand's personal journey with reintegration, alcohol, and balance in a city like Las Vegas, where indulgence is normalized.AI and Psychiatry: Making Mental Health Accessible to All:Dr. Zand's vision for the future of psychiatric care through Anywhere Clinic, an accessible and affordable online mental health service.How Anywhere Clinic is revolutionizing mental health care with telehealth, providing a more affordable and convenient option for psychiatric support through insurance coverage.Resources Mentioned in This Episode:Anywhere Clinic: A telehealth platform offering psychiatric care and ketamine therapy for patients in 30 states (and growing).Tori Gordon's Podcast Episode on Ketamine Therapy: Dive deeper into the transformative benefits of ketamine therapy.AI Therapy Tools: Dr. Zand's recommendation for self-guided AI therapy as a supplemental tool for emotional regulation.Get Involved:Follow Anywhere Clinic: Stay updated on new mental health tools, including AI therapy and more. Visit anywhereclinic.com for more information.Join the Conversation: Share your thoughts and experiences with AI therapy and shadow work on social media, using the hashtag #TheCoachablePodcast.Subscribe to the Podcast: Stay connected with Tori Gordon and expert guests as they continue to explore the transformative world of personal and collective healing.Connect with Dr. Sam Zand:Website: Anywhere ClinicInstagram: @drsamzandConnect with Us on SocialTori's Instagram: htttps://www.instagram.com/thetorigordonThe Coachable Podcast IG: https://www.instagram.com/thecoachablepodcastTori's Website: https://www.torigordon.com or https://www.revivelasvegas.comFinal Thoughts: In this enlightening conversation, Dr. Zand and Tori explore some of the most pressing and exciting developments in mental health. From AI-assisted therapy to the deep work of shadow integration and sexual healing, this episode encourages listeners to embrace both technology and spirituality in their journey to mental wellness. Whether you're exploring new therapeutic tools or reconnecting with your own shadow self, the path to healing begins with curiosity, courage, and a willingness to look in the mirror.Join the Movement: Mental health is cool—let's make it a conversation everyone can have openly. Don't forget to share this episode with a friend or loved one who might need to hear this empowering message today. To apply for private coaching or for media inquiries please email: hello@torigordon.com
In this podcast episode, we host Rebekah Schrader, Joseph Willi, Daniel Gorham and Gavin Horn, all from the FSRI, to cover their recent experimental research on fire spread through external walls. This is part 1 of the interview - the background, rationale and context. In part 2, we cover the experiments themselves, findings and actionable guidance from the experiments.This research is conducted within the context of structure-to-structure fire spread, potentially in urban conflagration scenarios. The subject is most relevant, as when wildfires meet urban areas, they transform into something far more destructive – "wildfire-initiated urban conflagrations." These events devastate entire communities as fire spreads rapidly from structure to structure, overwhelming firefighting resources and leaving widespread destruction in their wake.The Fire Safety Research Institute has embarked on a comprehensive research initiative examining exactly how these conflagrations develop and spread. What started as a response to their advisory board's call to action in 2018 has evolved into a groundbreaking exploration of the complex interactions between wildland fires and the built environment.We break down the three primary mechanisms of fire spread – radiant heat, direct flame contact, and firebrands – while highlighting specific vulnerabilities in modern construction, particularly windows and cladding systems.What makes this research particularly valuable is how it bridges traditionally separate disciplines: wildfire science and structural fire engineering. The team explains how they've translated complex wildfire scenarios into controlled laboratory experiments that yield actionable data for improving building codes and community design.Whether you're a fire safety professional, community planner, or homeowner in a wildfire-prone region, this conversation offers crucial insights into how we can create more resilient communities in the face of this growing threat.In the next episode, we will cover in depth the details of three experiments mentioned today.Find the research papers at:https://onlinelibrary.wiley.com/doi/10.1002/fam.3278https://link.springer.com/article/10.1007/s10694-024-01685-8https://link.springer.com/article/10.1007/s10694-024-01656-zAnd additional resources at:https://fsri.org/research-update/journal-article-reports-heat-transfer-through-different-window-constructionshttps://fsri.org/research-update/journal-article-investigates-role-residential-siding-materials-spread-exterior----The Fire Science Show is produced by the Fire Science Media in collaboration with OFR Consultants. Thank you to the podcast sponsor for their continuous support towards our mission.
Anywhere Clinic: https://www.anywhereclinic.com/ Dr. Sam Zand IG: https://www.instagram.com/drsamzand?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Join our Big Book Study! https://www.realrecoverytalk.com/bigbookstudy Join our FREE FB Support group!: https://www.facebook.com/groups/realrecoverytalk Download our free guides!: https://www.realrecoverytalk.com/guides Chat with us! https://www.realrecoverytalk.com/services In this episode, we're joined by Dr. Sam Zand, founder of Anywhere Clinic, to talk about the evolving landscape of addiction treatment. Dr. Zand shares what he's learned over the years working with substance abuse patients and what truly makes a difference in their recovery journey. We dive into some of the cutting-edge treatments that are starting to gain traction in the mental health and addiction world, and we also take a hard look at where modern medicine has missed the mark—especially when it comes to truly healing the whole person. If you're curious about what's next in addiction recovery, what needs to change in how we treat it, and how we can bridge the gap between science and compassion, this is a conversation you don't want to miss.
Den svenska byråkratin strikes again! Våra säsongstips skickas ut i etern! Genombrott?! Skyttekung?! Henriksson siktar _inte_ på nytt rekord i gula och Zandén berättar om klubbval och stortalangerna i BP! Nerverna och icke-nerverna i FörsäsongSvenskan!TuttoSvenskan görs i samarbete med:TV4 Play:Svenska Cupen börjar idag! Via vårt samarbete med TV4 Play streamar du Svenska Cupen, Allsvenskan, Superettan, Serie A, La Liga, Landskamper och MYCKET annat för 249kr/mån (ord 349kr). Ni har erbjudandet här: https://www.tv4play.se/kampanj/tuttoATG:Läs om våra senaste tankar gällande spel på: https://www.atg.se/tutto - 18 år gäller för spel och stödlinjen.se finns om du upplever minsta problematik med spelandeMQ:Vårens kampanj hyllar den sofistikerade och ledigt eleganta stilen. Inspirerad av den italienska vårens färger och tidlös design, kombinerar kollektionen klassiska linnekostymer, luftiga skjortor och noggrant utvalda accessoarer. Vi har såklart en kod - MQ20 ger 20% rabatt på MQs egna varumärken om du köper två eller fler plagg, gäller online samt butik.Läs mer: https://www.mq.se/inspiration/kampanjer/spring-classics-herr/Lenovo:Lenovo är EXKLUSIV huvudpartner till årets FörsäsongsSvenskan. Vi vill uppmärksamma er som är ute efter en ny bärbar dator att Lenovo Aura Edition finns där ute på marknaden. Läs mer om den här: https://www.elgiganten.se/product/datorer-kontor/datorer/laptop/lenovo-yoga-slim-7i-u7-258v321tb-153-copilot-pc-aura-edition/804948Allsvenskan Fantasy:Som vi har väntat men nu är äntligen Allsvenskan Fantasy live! In och joina vår liga, vinn den om du kan och få evig ära samt berömmelse
Recent mocht ik twee onderwijs sessies verzorgen voor Bijbelschool Filadelfia, Hebron Missie te Amerongen. In dit tweede deel spraken we over hoe gemakkelijk het is voor Nederlandse christenen om in de praktijk van hun leven hun huis op het zand te bouwen in plaats van op Jezus' Woorden. Onderwerpen die aan de orde kwamen waren o.a. seksualiteit en geld. Ik hoop dat deze boodschap jou tot zegen zal zijn.
De meeste meegereisde supporters naar Antwerpen hebben ongetwijfeld een leuke dag gehad, maar de wedstrijd was helaas een hinderlijke onderbreking, want Donar verloor kansloos in de een Lotto Arena, waar zelfs de thuissupporters met verbazing zaten toe te kijken.
Recent mocht ik twee onderwijs sessies verzorgen voor Bijbelschool Filadelfia, Hebron Missie te Amerongen. In dit eerste deel spraken we over hoe gemakkelijk het is voor Nederlandse christenen om in de praktijk van hun leven hun huis op het zand te bouwen in plaats van op Jezus' Woorden. Ik hoop dat deze boodschap jou tot zegen zal zijn.
➡️ Eerst even dit. Op 7, 8 en 9 maart vinden de doopsgezinde studiedagen weer plaats. Dit weekend staat in het teken van benoemen waar het werkelijk om gaat. Het is een weekend vol vieren, zingen, luisteren, bidden, stil worden en ontmoeten. Het is een weekend van nieuwe vormen, van nieuwe vieringen en hier hebben we jou voor nodig. Om samen te leren, te delen, te vieren. Want geloven doe je niet alleen. Je kunt je nu opgeven via www.dopersduin.nl/studiedagen. En Wieteke en Wiebe zullen ook aanwezig zijn. --- Droogte. Zand. Leegte. De woestijn. Een plek van dood en sterven. Maar ook een plek van de toekomst een waterput en ja, ook hoop. In deze nieuwe reeks van Gelukkig de mens gaat het over de woestijn. Een plek die veelvuldig voorkomt in de bijbel. En deze week beginnen we in het begin. We beginnen bij Genesis. Bij Abram, Sarai en Hagar. Luister nu de nieuwste aflevering van Gelukkig De Mens: Hoopvol via #spotify, #pocketcasts, #applepodcasts, www.gelukkigdemens.nl/168-verhalen-uit-de-woestijn-deel-1 in je eigen podcastapp. Genesis 16 Abrams vrouw Sarai baarde hem geen kinderen. Nu had zij een Egyptische slavin, Hagar. ‘Luister,' zei Sarai tegen Abram, ‘de HEER houdt mijn moederschoot gesloten. Je moest maar met mijn slavin slapen, misschien kan ik door haar nakomelingen krijgen.' Abram stemde met haar voorstel in en Sarai gaf hem haar Egyptische slavin Hagar tot vrouw; Abram woonde toen tien jaar in Kanaän. Hij sliep met Hagar en zij werd zwanger. Toen Hagar merkte dat ze zwanger was, verloor ze elk respect voor haar meesteres. Sarai zei tegen Abram: ‘Voor het onrecht dat mij wordt aangedaan ben jij verantwoordelijk! Ik heb je mijn slavin ter beschikking gesteld, en nu ze weet dat ze zwanger is toont ze geen enkel respect meer voor mij. Laat de HEER maar beoordelen wie er in zijn recht staat: ik of jij.' Abram antwoordde: ‘Het is jouw slavin, doe met haar wat je goeddunkt.' Toen maakte Sarai haar het leven zo zwaar dat ze vluchtte.
De tijd vliegt in de Saoedisch woestijn. Inmiddels zitten we halverwege de slotweek van de Dakar Rally en staan we aan de vooravond van de slotetappes in het Empty Quarter. Dit betekent zand, duinen en niks anders zover het oog reikt. Laat dit nu toevallig het favoriete terrein zijn van Richard de Groot van het Firemen Dakar Team. We spraken met hem over hoe ze ervoor staan drie etappes voor het einde. Presentatie: Robert Denneman
In deze aflevering heb ik het over de redenen waarom paarden zand eten
Debby van der Zande bij Andy in de auto! Modeontwerper, ondernemer en influencer uit Oldenzaal. Bekend van haar modezaken Dejacque en Zand, waar ze ook populaire vlogs over maakte. Sinds vorig jaar is ze begonnen met het maken van kookvideo's, waarmee ze opnieuw viraal gaat en het grote publiek weet te bereiken. Geweldige, leuke, slimme vrouw en mooi om deze Topper in de auto te hebben!
Spijkers is back, Baby! Ja oke... het is ook weer niet zo dat we heel erg lang weg zijn geweest hoor, maar toch zijn we met het hele Spijkers met Koppen team helemaal in onze nopjes dat je ons ook in 2025 digitaal hebt weten te vinden! Hulde voor jou, maar ook hulde voor onze gasten vandaag die komen met verhalen over Russische bunkers en of het nou eens ein-de-lijk vrede op aard wordt in 2025 en dan gaat het ook nog over het énorme tekort aan zand in ons land! En ook: * Misschien wel dé nieuwe Nederlandse hitmachine * Kan je iedere week iets nieuws uitvinden? (spoiler: ja) Presentatie: Willemijn Veenhoven & Dolf Jansen Cabaret: Shariff Nasr, Kiki Schippers en Aron Elstak Column: Sezgin Güleç Livemuziek: Tangerine
Wat maakt Aimée de Jongh zo succesvol? Ontdek het in deze aflevering! Aimée de Jongh is een Nederlandse animator, stripauteur en illustrator, wiens werk internationaal wordt gewaardeerd. We duiken in haar indrukwekkende carrière, van het verstrippen van klassiekers zoals Lord of the Flies tot haar geprezen boeken Dagen van Zand en Taxi. Aimée deelt openhartig hoe ze graphic novels maakt, haar inspiratie vindt, en wat er allemaal komt kijken bij het balanceren tussen creativiteit en ondernemerschap. Twijfel je weleens of jouw ideeën goed genoeg zijn? Aimée vertelt hoe zij doorzet, ook na afwijzingen, en waarom blijven proberen altijd loont. Luister mee voor inspirerende inzichten, praktische tips en een kijkje achter de schermen van een van Nederlands meest getalenteerde stripmakers!
De winnaar van het afgelopen weekend – Eli Iserbyt – is te gast bij Sander Valentijn, Jeroen Vanbelleghem, Bobbie Traksel en Thijs van Amerongen. Na een moeilijke start van het seizoen won hij zowel in Kortrijk als de eerste wereldbeker van het seizoen in Antwerpen. Eli vertelt over zijn start van het seizoen, de zandbak in zijn tuin en waarom de top dit jaar zo dicht bij elkaar ligt. Daarnaast bespreken we met hem niet alleen zijn meest recente, maar ook zijn allereerste overwinning. Daarvoor in het nieuws aandacht voor een nieuwe veiligheidsmaatregel, de soap rondom de start van de Giro en het vertrek van Van Gils en waarom we misschien wel hele andere namen in de cross gaan zien. Tot slot kijken we vooruit naar de wereldbeker cross in Dublin en – dichter bij huis – de Track Champions League het aankomende weekend in Apeldoorn. Hosted on Acast. See acast.com/privacy for more information.
We 'raten' de dag op een schaal van depressie en we scoren hoog! Wantja, het sneeuwt, Mado krijgt weer dikke facturen voor haar paarden waar ze niet op rijdt en Jill heeft amper een onderdak voor haar paarden.
Send us a textIn this episode of Soul of Travel, Season 6: Women's Wisdom + Mindful Travel, presented by @journeywoman_original, Christine hosts a soulful conversation with Shayna Zand.As WeTravel's Director of Partnerships & Enterprise Sales, Shayna Zand brings with her 12+ years in the tour operator space and working with various partners in the travel industry. She joined the team in May 2022 to build relationships with existing and new partners. She also is the Vice-Chair on the Board of Directors for Tourism Cares and is based in Toronto, Canada. She loves to travel and has had the pleasure of visiting 85+ countries.Christine and Shayna discuss:· Shayna's transition from a tour leader to director and her roles in the travel industry· How to increase the representation of women in travel leadership roles· The role of WeTravel in supporting initiatives like Women in Travel CIC, mentorship programs, and allyship in the workplace· Continuing commitments to sustainability, client growth, and educational resources· Vulnerability in leadershipJoin Christine for this soulful conversation with Shayna Zand.
Anke, Harrie en Tjietse nemen plaats op De Restzetel en vertolken de ongehoorde stem. In deze aflevering bespreken we: Hallo Hans / foto gemeenteraad / Kelly van Zon / communicatieonderzoek / AZC samenwerking met Loon op Zand / opvang Oekraïners in Dongen-Vaart / €700.000,- voor gemeentesecretaris H. van Noort / De begroting: persgesprek met college (vanaf: 40:35 min). Volg De Restzetel via: Website Instagram Facebook Mail: contact@restzetel.nl WhatsApp-updateservice: 06 822 544 91
Annemieke Bosman praat met striptekenaar Aimée de Jongh over haar graphic novel Lord of the Flies, naar de klassieke roman William Golding. Lang voor The Hunger Games en Battle Royale was er al Lord of the Flies. Een groep kinderen moet na een vliegtuigongeluk zien te overleven op een tropisch eiland. Er zijn geen volwassenen om hen te helpen. Blauwe luchten, gele stranden, weinig bedreigingen: het lijkt een idyllische plek. Maar het duurt niet lang voordat hun onbezorgde leven verandert in een nachtmerrie. Wat gebeurt er als kinderen, jong en onschuldig, overgeleverd zijn aan elkaar? Nobelprijswinnaar William Golding toont ons in Lord of the Flies zijn visie op de mens, een visie die na de oorspronkelijke publicatie in 1954 een miljoenenpubliek bereikte, en die nog altijd actueel is. Ter ere van het 70-jarig bestaan verschijnt de klassieker nu voor het eerst als graphic novel, geschreven en getekend door de Nederlandse stripauteur Aimée de Jongh. Met de bestseller Dagen van Zand wist zij al wereldwijd een groot publiek te bereiken en talloze prijzen te winnen. Met Lord of the Flies stijgt ze boven zichzelf uit. De Jongh wilde deze graphic novel al 10 jaar lang maken. Nu, met de zegen van de familie Golding, is het eindelijk zover.
De allereerste Buren van de Brandweer - de Podcast live! Op locatie bij Café Brasserie De Kiosk in Loon op Zand hebben we, in het bijzijn van een fantastisch publiek, een aantal vurige onderwerpen besproken! Luister deze bonus aflevering nu via je favoriete podcast app!
En tuff förlust mot Sirius tar ned oss på jorden igen. Har våra motståndare nu läst av oss hur vi spelar? Varför gjorde Besfort Zeneli så mycket misstag? Det finns mycket frågetecken i dagens poddavsnitt.
Vor zwölf Monaten Jahr überfiel die Hamas Israel. Seither dreht sich eine Spirale der Gewalt. Diese Eskalation war wohl das eigentliche Ziel der Terroristen. Ein Jahr nach dem Hamas-Terror des 7. Oktober steht die Region am Rand eines großen Krieges. Israels Premier Benjamin Netanyahu weitet den Kampf gegen die Hisbollah im Libanon aus, und der Iran attackiert Israel direkt: Ist eine Katastrophe noch vermeidbar? In dieser Folge von »Acht Milliarden« spricht Host Juan Moreno mit SPIEGEL-Korrespondent Bernhard Zand über ein blutiges Jahr im Nahen Osten. 1.200 tote Israelis, geschätzte 41.000 tote Palästinenser. Doch die Region, schon immer ein Pulverfass, steht weiter vor einem Desaster. Und die Frage ist: War das absehbar? Zand ist zumindest nicht überrascht: »Ich vermute, dass der Hamas-Führer den Gedanken hatte, er entzündet mit dem Terroranschlag des 7. Oktober den Nahen Osten insgesamt. Dieser Plan scheint jetzt ein Jahr später tatsächlich aufzugehen. Und das ist natürlich bitter, dass wir alle praktisch in dieser Falle sitzen.«+++ Alle Infos zu unseren Werbepartnern finden Sie hier. Die SPIEGEL-Gruppe ist nicht für den Inhalt dieser Seite verantwortlich. +++ Den SPIEGEL-WhatsApp-Kanal finden Sie hier. Alle SPIEGEL Podcasts finden Sie hier. Mehr Hintergründe zum Thema erhalten Sie bei SPIEGEL+. Jetzt für nur € 1,- für die ersten vier Wochen testen unter spiegel.de/abonnieren Informationen zu unserer Datenschutzerklärung.
Psychedelics offer a new frontier in psychiatry, providing profound shifts in perspective that can enhance therapeutic outcomes. In this episode, Dr. Sam Zand, founder of Anywhere Clinic, a holistic psychiatrist and professor of psychedelic medicine, shares insights into his immersive wellness retreat in Puerto Rico, where patients experience a combination of nature therapy, meditation, and ketamine therapy to reset their mental health. He also talks about his entrepreneurial journey, the growth of telepsychiatry, and the integration of new treatment modalities like ketamine in mental health care. Dr. Zand covers the challenges of scaling mental health services, addressing the cost barriers to treatments, and the role of psychedelics in transforming psychiatric care. He also emphasizes the importance of personal mental health in achieving success and unlocking one's full potential. Tune in and learn how innovative approaches to mental health can enhance both personal well-being and professional effectiveness! Resources: Watch the entire interview here. Connect and follow Dr. Sam Zand on LinkedIn. Learn more about Anywhere Clinic on their LinkedIn and website.
Send us a textBuy tickets for the TellyCast Digital Content Forum 2024This week, our guest is a truly unique storyteller, someone who has carved out a distinct niche in the world of documentaries. Ben Zand's work takes us to some of the most unexpected corners of the globe, shedding light on untold stories and giving a voice to those often unheard. You may know him from his captivating series under the Zandland banner, where he combines journalism with a personal touch that keeps viewers on the edge of their seats.Support the showBuy tickets for the TellyCast Digital Content Forum 2024Subscribe to the TellyCast YouTube channel for exclusive TV industry videosFollow us on LinkedInConnect with Justin on LinkedINTellyCast videos on YouTubeTellyCast websiteTellyCast instaTellyCast TwitterTellyCast TikTok
This episode is a double - the 2024 Dutch GP review and the 2024 Italian GP preview. Yes, it's a double header, and we're making space in our publishing calendar. But making space for what or for who? Well you'll know soon. Check out the Inside Line F1 Podcast on Thursday this week...and Thursday next week. We're getting one of our headline guests back on the show. How did McLaren win by 22 seconds in Zandvoort? Can they win again in Monza? Why was Red Bull Racing just so slow in Zandvoort? Will the top-4 teams be even closer at Monza? The 2024 Italian GP will see teams choose their lowest downforce setting. Basically, they will shed ALL the drag they can. As much as love Monza for the history, the Tifosi and the iconic corners, the one thing that we HATE it for are DRS trains. At Zandvoort, we saw overtakes across the entire grid. Let's see how Monza copes on the overtaking front...and even more so with DRS trains. At Zandvoort, Ferrari over-delivered on Sunday. They pulled off a masterstroke of a tyre strategy with Charles Leclerc. LEC undercut George Russell and Oscar Piastri during his single stop. Will Ferrari continue to shine in Monza in front of their beloved Tifosi? Also, who will be the most-popular Ferrari driver at Monza - Charles Leclerc, Carlos Sainz or Lewis Hamilton. Lewis Hamilton's recovery drive from P14 to P8 at Zandvoort was much-heralded, much as George Russell's drop-off from a podium position to P7. After impressing in the races just before the summer break, what happened to Mercedes at Zandvoort? And can they re-join the battle at the front in Monza? Mercedes' BIG high moment will be when Andrea "Kimi" Antonelli jumps into Russell's car during FP1 to make his Formula 1 debut. Will Mercedes also use this opportunity to confirm Formula 1's worst kept secret about their replacement for Hamilton? Lots in store in this hour-long episode, tune in! (Season 2024, Episode 42) Follow our hosts on Twitter: Soumil Arora, @f1statsguru and Kunal Shah Image courtesy: McLaren
“Send us a Hey Now!”It was the return of cars on track this week as F1 arrived in Zandvoort for the Dutch GP.Both Rob & Brian can't quite work out if they enjoyed the race or not!The guys pull the race weekend apart and debate the best bits and worst bits and finally make a decision on whether they enjoyed it or not.As well as the race review we have our usual round up of what caught our eye in the news and on social channels. We have the video vault and a preview of Monza.Oh, and the F1 Fantasy game actually calculated quickly so we can talk about that as well!1) News & SocialAll the best bits from both the sports news out there as well as what caught our eye on the various social channels2) Brian's Video Vault https://www.youtube.com/watch?v=vfr5LAqlVWI. Track Tours with Valtteri: Valtteri Bottas' ULTIMATE track guide for ZANDVOORT. Sauber Motorsport channel. 3.5 mins. Long Arm Valtteri is so good - showing the banking. He says banking so many times in this video!https://www.youtube.com/watch?v=OFpoIgD-Re0. Earliest F1 Winners Challenge | Grill The Grid 2024. Formula 1 channel. nearly 12 mins. Was fun - esp to see of the drivers on the list rank themselves3) Dutch GP ReviewPractice, qualy, and race reviewKing of the pits vs the pitsPitlane Paul4) Italian GP PreviewWe would love you to join our Discord server so use this invite link to join us https://discord.gg/XCyemDdzGBIf you would like to sign up for the 100 Seconds of DRS then drop us an email stating your time zone to dirtysideofthetrack@gmail.comAlso please like, follow, and share our content on Threads, X, Facebook, & Instagram, links to which can be found on our website.One last call to arms is that if you do listen along and like us then first of all thanks, but secondly could we ask that you leave a review and a 5 star rating - please & thanks!If you would like to help the Dirty Side promote the show then we are now on Buy me a coffee where 100% of anything we get will get pumped into advertising the show https://www.buymeacoffee.com/dirtysideofthetrackDirty Side of the Track is hosted on Buzzsprout https://www.buzzsprout.com/Support the Show.
This week Mike and Max are back from their summer break. They discuss Ocon moving to Haas, where Adrian Newey is going to end up, and the new pop-up children's book: 'Bernie Bought Brabham'.
Stefan, Thomas en Laurens gaan verder. Nog maar één week Tour, nog maar 12 podcasts te gaan. De onderwerpen vliegen de tafel over - de chipsgooier, Thomas' zinsgeving, UAE en los zand, Visma tegen beter weten in, een gedeclasseerde Girmay, boeketoe, grupetto's die op magische wijze minuten tijd goedmaken. De hamvraag: moeten we voor een spannende Tour nu op zoek naar de verhalen uit de tweede lijn, de verhalen van de Almeida's? Eén ding is zeker: Nice is nog ver. En hoe zat het nou met het dichtgooien van deuren in de tussensprints? Je hoort het allemaal in de Live Slow Ride Fast podcast.
On today's episode, we have Psychiatrist Dr. Sam Zand (He/Him) join us for a conversation about finding your unique path to healing. Together we talk about building neuro plasticity through play, how community is medicine, and the impact of SSRIs and Psychedelics on sexuality. If you enjoyed today's podcast, then please subscribe, leave a review, or share this podcast with a friend! To learn more, head over to the website www.modernanarchypodcast.com And if you want to connect deeper with the Modern Anarchy Family and support the long term sustainability of the show, then join the movement by becoming a part of the conscious objectors patreon. Join the community here: https://www.patreon.com/user?u=54121384 Looking to work with Nicole: https://www.modernanarchypodcast.com/pleasure-practice Intro and Outro Song: Wild Wild Woman by Your Smith Modern Anarchy Community: Website : www.modernanarchypodcast.com Instagram: https://www.instagram.com/modernanarchypodcast Patreon : https://www.patreon.com/user?u=54121384 Dr. Sam Zand's Community: Websites: www.drsamzand.com www.betterUcare.com www.AnywhereClinic.com Instagram: https://www.instagram.com/drsamzand/ Resources to Learn More: SSRI are not effective for mild depression: https://www.ncbi.nlm.nih.gov/books/NBK361016/ Cocaine and Neuroplasticity: https://pubmed.ncbi.nlm.nih.gov/18345022/ Disagreement between clinicians is the norm, not the exception: https://www.psychologytoday.com/us/blog/flex-your-feelings/202206/the-myth-mental-health-diagnosis
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Drs. Gabriel Levin and Behrouz Zand to discuss ChatGPT-fabricated abstracts in gynecologic oncology. Dr. Gabriel Levin is a gynecologic oncology Fellow at McGill University, and an assistant professor at the Hebrew University of Jerusalem. His research encompasses population database studies with clinical implication and innovations in medical education and health care. Dr. Behrouz Zand is a gynecologic oncologist at Houston Methodist Hospital's Neal Cancer Center and Department of Obstetrics and Gynecology, and an assistant professor at Weill Cornell College at Houston Methodist Academic Institute. Specializing in innovative cancer care and clinical trials, he is passionate about integrating AI in medicine, a recent alumnus of the physician program at MIT for AI integration in healthcare. Dr. Zand combines cutting-edge research with compassionate patient care to advance the field. Highlights: Reviewers had difficulty in discriminating ChatGPT-written abstracts. Reviewers correctly identified only 46.3% of ChatGPT-generated abstracts, with human-written abstracts slightly higher at 53.7%. Senior reviewers and those familiar with AI had higher correct identification rates, with senior reviewers at 60% and juniors/residents at 45%. Experience and familiarity with AI were independently associated with higher correct identification rates. ChatGPT assists researchers by generating reviews, summaries, and enhancing writing clarity, but it raises ethical concerns and could diminish human expertise. For non-English speaking authors, it improves writing quality and clarity. In scientific writing, it enhances clarity, summarizes concisely, brainstorms ideas, assists with terminology, and offers data interpretation, augmenting human expertise. ChatGPT and AI in scientific writing can lead to ethical issues, factual inaccuracies, and may eventually diminish human expertise and critical thinking.
The revival of Shi‘ite Sufism, after the destruction of Safavid empire, occurred during the Zand dynasty (1163-1209/1750-1794) and continued through the Qājār era. As Zarrīnkub has pointed out, the Qājār era was a time of nostalgia for the noble past. Of course, their mystical philosophy had to fit the theological standards of Shi‘ite society. The two leading Sufi orders in this revival movement were the Ni‘matullāhīs and the Dhahabīs. These two orders had much in common, as both of them highly emphasized the importance of following Islamic laws and Shi‘ite beliefs. They were known to be the propagators of Akbarian philosophy in Persia. Dhahabīs and Ni‘matullāhīs were strong promoters of the school of “Unity of Being” (Waḥdat al-wujūd). Mīrzā Muḥammad Taqī, with the spiritual title of Muẓaffar ‘Alī Shāh (d.1215/1800) is one of the most influential masters in the history of Ni‘matullāhiyya order. This Shi‘ite Sufi master is one of the most active and knowledgeable masters of the Ni‘matullāhīs during this era. He is the first master after the return of the order to Persia who wrote about its cosmological views, based on the philosophy of “Unity of Being”. In his youth, he began studying the rational and traditional seminary sciences (‘ulūm ‘aqlī wa naqlī) and became well-versed in them. Muẓaffar was more of a mystic philosopher (ḥakīm) than a jurist (faqīh), and extremely well-versed in speculative Sufism, following the school of “Unity of Being”. Muẓaffar ‘Alī Shāh's mystical poetry had in-depth mystical meanings, with heavy reliance of Ibn ‘Arabī's philosophy and terminology. Muẓaffar was very influential for the development of the Ni‘matullāhī order and as a propagator of Ibn ‘Arabī's thoughts. His beliefs about the perfect man, insān-i kāmil, were highly influenced by Akbarian (Ibn ‘Arabī's) philosophy. Muẓaffar passed away in 1215/1800. He wrote numerous books and literary papers, which are tremendously valuable for a better understanding of Ni‘matullāhī thought. Muẓaffar ‘Alī Shāh wrote poetry lamenting over his separation from his master, Mushtāq, to whom he dedicated a compendium of his poetry, calling it Diwān-i Mushtāqīyya. In this paper, we will examine two of Muẓaffar's writings: “Sea of the Secrets” (baḥr al-asrār) and “Compendium of the Seas” (majma‘ al-biḥār) which are both interpretations of the first chapter of Quran. “Sea of the Secrets” (baḥr al-asrār) is in verse form of Mathnawī and “Compendium of the Seas” (majma‘ al-biḥār) is written in prose. In these two works, Muẓaffar ‘Alī Shāh heavily relied on the chapter of Prophet Adam in Fuṣūṣ al-ḥikam of Ibn ‘Arabī. He had numerous references to Ibn ‘Arabī and his writings. Muẓaffar ‘Alī Shāh explains the relationship between Nubuwwa (prophethood), Risāla (apostleship) and Wilāya (sainthood) based on Ibn ‘Arabī's teachings using his terminology like the disclosure of Attributes of Divine Majesty (jalāl) and disclosure of Attributes of Divine Beauty (jamāl). This paper investigates the importance of Muẓaffar ‘Alī Shāh for survival of the school of “Unity of Being” among practicing Shi‘ite Sufis in general and the Ni‘matullāhī Sufi in particular as one of the most important Shi‘ite Sufi orders in Iran.
James Bond-achtig avontuur over Alex (12) die undercover gaat om zijn vermiste moeder te zoeken. Hij belandt in een spannend safari-avontuur waarbij ze in de ruige natuur op dieren moeten jagen. Uitgegeven door Van Goor Spreker: Kevin Hassing
It can feel like improvements are needed in nearly every aspect of digital healthcare; from cybersecurity and clinical optimization to a focus on patient and consumer engagement and revenue cycle… How can we address vital digital health enhancement opportunities and not only survive, but thrive? “I think it really comes down to prioritization.” This installment of the Leader to Leader podcast, hosted by Russ Branzell, President and CEO of CHIME, and featuring Peyman S. Zand, the Chief Strategy Officer at CereCore, hones in on the value of precision and prioritization. The digital health arena is vast, with areas ripe for optimization and enhancement constantly evolving. How can we improve digital healthcare in a way that is efficient and practical? The answer: you develop a strategy of prioritization and focus on key areas that need systematic advancement the most. Discover strategies for achieving greater precision and strategic focus in driving improvements within your healthcare institution by engaging with this podcast episode now.
Dr. Sam Zand, Holistic Psychiatrist & Professor of Psychedelic Medicine, brings us a lot of hope for the future of mental healthcare. Last time we spoke to Dr. Zand, we focused specifically on ketamine assisted therapy. Today, we cover everything from the psychodynamic history of drugs and mental health treatment to integrating spiritual practices into medicine. Dr. Zand is a practicing psychiatrist who has trained over 100 clinicians in holistic mental health and also teaches psychedelic medicine and holistic psychiatry at UNLV. As founder of Anywhere Clinic, Calm Clinic, and Better U, Dr. Zand has utilized his Johns Hopkins public health training to help deliver insurance covered, compassionate mental health care in over 10 states. MORE DR. ZAND:https://www.drsamzand.com/https://www.anywhereclinic.com/https://www.instagram.com/drsamzand/Check out Anywhere Clinic's free virtual support groups here: https://www.anywhereclinic.com/freegroupDon't forget to DM us on IG or submit a question on thoughtsmayvary.com to have your question or theme unpacked on a future episode! SHOP “CO-CREATE” TMV'S MANIFESTATION JOURNAL: https://www.thoughtsmayvary.com/the-tmv-shopDiscount codes, extra unpackings, journal prompts, vlogging (+more!) all happening with our familia over on Patreon. Come hang out — https://www.patreon.com/thoughtsmayvary
Our researcher Shauna headed off to meet a selection of students from 1st and 2nd class at St Peter's National School in Dunboyne in Meath She spoke to Leah, Indy, Shauna, Luke, Alexandre, Ryan, William P, Zand, Nathan, William B, Michael and Amelia and quizzed them about perfume for babies and parents struggling with primary school level homework. Click play now to hear what they had to say!
In this episode, we're joined by Dr. Sam Zand, a Holistic Psychiatrist and Professor of Psychedelic Medicine. We delve into one of my current favorite topics - the emerging role of psychedelics in modern psychiatry, exploring how they may offer new hope for treating mental health conditions such as depression, anxiety, PTSD, and more. Dr. Sam shares insights into the current research on psychedelics and their potential to facilitate healing, as well as the challenges and ethical considerations surrounding their use. We also introduce and talk about an upcoming Ketamine Retreat we are hosting here in Las Vegas on December 2nd. Tune in for a fascinating discussion on this cutting-edge topic in the field of mental health. Reserve your spot for the December 2nd Ketamine Retreat in Las Vegas Connect with Dr. Sam: INSTAGRAM LINKEDIN WEBSITE ANYWHERE CLINIC Connect with Tori: TIKTOK INSTAGRAM COACHABLE YOUTUBE COACHABLE INSTAGRAM COACHABLE FB COMMUNITY Join My Community Membership - THE HUDDLE OUR SPONSORS: My FAVORITE daily accessory (a PERFECT GIFT) - the Komuso Shift Necklace! With Komuso you can breathe easier, think clearer, and live better. Check them out today at komusodesign.com/COACHABLE and receive 15% off! Take the first step toward a more serene and empowered you! Learn more about your ad choices. Visit podcastchoices.com/adchoices
I'm really excited to dig into a new topic you've been asking about – psychedelic therapy. Today, Derek Du Chesne and Dr. Sam Zand demystify the sometimes controversial practice and explain how it is transforming the future of mental health treatment. Derek and Dr. Zand are the co-founders of Better U, an alternative mental health platform that offers at-home ketamine therapy and other holistic healing modalities. Their mission is to evolve our understanding of mental health – shifting the conversation from mental illness to mental wellness. In today's episode, Derek and Dr. Zand break down what ketamine therapy actually is, and how it's different from the party drug and “horse tranquilizer” you may have heard of. We talk about how psychedelic therapy is used as just one part of a holistic approach to move through depression, anxiety, and grief – exploring how ketamine allows people to quiet their inner programming to uncover hidden perspective, purpose, and alignment. Derek and Dr. Zand also share their perspectives on chemical imbalances, the effects of psychedelics vs. alcohol, and their compassionate advice for anyone struggling with their mental health right now. This episode is for anyone who is curious and open minded. Share it with your friends to spark a new conversation.Resources:Instagram: @betterucareWebsite: betterucare.comDerek Instagram: @derekdddDr. Zand Instagram: @drsamzandPodcast Episode: How to Shift Your Self-Talk & Live Fearlessly with Katie Horwitch Read: The Big Silence: A Daughter's Memoir of Mental Illness and Healing Follow Karena Dawn on Instagram: @karenadawnFollow The Big Silence on Instagram: @The.Big.SilenceSubscribe: The Big Silence YouTube ChannelTherapy For All: Resources for those in needDonate to The Big Silence thebigsilence.com/donate to be a part of the movement to break the silence and make noise with us!“The Big Silence” theme song written and performed by James Nicholas Kinney.Producer, Bobby Goldstein.The Big Silence is produced by Crate Media.
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If you care about what you eat, you won't want to miss this conversation! Chris Van Tulleken is an infectious disease physician-scientist in the UK's National Health Service who has written a deeply researched masterpiece book on food—ULTRA-PROCESSED PEOPLE. It's not just about these synthetic and artificial UPF substances, that carry many health hazards, but also about our lifestyle and diet, challenging dogma about low carbs/glycemic index and the impact of exercise. Chris ate an 80% UPF diet for a month with extensive baseline and follow-up assessments including MRI brain scans. He has an identical twin brother who at times is 20 kg heavier than him. Why? What can be done to get limit pervasive UPF ingestion and its multitude of adverse effects on our health?For additional background to the book, here are some Figures and a Table from a recent BMJ piece by Mathilde Touvier and colleagues.Consumption of UPFs are highest in the USA and UKA Table summarizing some of the health hazards and magnitude of increased riskIn his book Chris gets into the evidence for risks that are much broader than cardio- metabolic, including cancer, dementia, inflammatory bowel disease, and other chronic conditions. A schematic for how UPFs increase the risk of cardiometabolic diseasesHere is the transcript of our conversation, unedited, with links to the audio podcast.Recorded October 20, 2023.Eric Topol (00:00):It's Eric Topol here with Ground Truths. And what a delight for me to welcome Chris van Tulleken, who has written a masterpiece. It's called Ultra-processed People, and it's actually much more beyond ultra-processed food as I learned. We're going to get into how it covers things like exercise, nutrition in general, all sorts of things. Welcome, Chris.Christoffer van Tulleken (00:27):It's such a pleasure to be here. And there's no one I would rather say that about my book than you, so that means a huge amount.Eric Topol (00:35):Well, I was kind of blown away, but I have to tell you, and it's probably going to affect my eating behavior and other things as we'll discuss for years to come. You're going to be stuck in my head. So what's interesting, before we get into the thick of it, your background, I mean as a molecular virologist turned into a person that devoted so much to food science, and you go through that in the book, how you basically got into rigorous reviews of papers and demand for high quality science and then somehow you migrated into this area. Maybe you could just give us a little bit of background on that.Christoffer van Tulleken (01:20):So I suppose it feels a tenuous thing. I'm an infectious diseases clinician, but the only people who get infections are disadvantaged people. For the most part, rich people well off people get cardiometabolic disease. And so I worked a lot in very low income settings in South Asia and Pakistan in the hills and in Central and West Africa. And the leading cause of death in the kids I was seeing in the infants was the marketing of food companies. So food, particularly formula, but also baby food was being made up with filthy water. And so these children were getting this triple jeopardy where they were having bugs, they were ingesting bugs from filthy water. Their parents were becoming poor because they couldn't afford the food and they lacked the immune system of breast milk in the very young. And so it sort of presented itself, although I was treating infections that the root of the problem was the food companies. And now my work has sort of expanded to understanding that poor diets has overtaken tobacco or it's depending on the number set you look at, but the Lancet Global health data shows that poor diets overtaken tobacco is the leading cause of early death globally. And so we need to start thinking about this problem in terms of the companies that cause it. So that's how I still treat patients with infections, but that was my route into being interested in what we call the commercial determinants of health.Eric Topol (02:52):Yeah, well you've really done it. I have 15 pages of highlights and notes that I got from the book and book. I mean, wow. But I guess the summary statement that somebody said to you during the course of the book, because you researched it heavily, not just through articles, but talking to experts that ultra-processed foods is not food, it's an industrial produced edible substance, and really it gets graphic with the bacteria that's slime and anthem gum and I mean all this stuff, I mean everywhere I look, I see. And I mean all these, I mean just amazing stuff. So before we get into the nitty gritty of some of these additives and synthetic crap, you did an experiment and with the great University College in London where you took I guess 80% of your diet for a month of up pfs. So can you tell us about that experiment, what it did for you, what you learned from it?Christoffer van Tulleken (04:04):Yeah, so it wasn't just a stunt for the book. I was the first patient in a big study that I'm now running. It's a clinical trial of ultra-processed food. And so I was a way of gathering data. I mean, you know how these things work, Eric. I was teaming up with my neuroscience colleagues to do MRI scans my metabolic colleagues instead of going, look, if we put patients on this diet, how would it all look and what should we be investigating if we do MRI scans, will we see anything? And so I ate various news outlets have portrayed this as kind of me heroically putting my body on the line for science. I ate a completely normal diet for many American adults. About one in five Americans eats the diet of 80% of their calories. It's a very typical diet for a British or an American teenager or young person.(04:52):So it wasn't arduous. And I was really looking forward to this diet because like most 45 year old doctors, I have started because of my marriage and my children, you start to eat in a rather healthy way. And this was amazing opportunity to go back to eating the garbage that I'd eaten as a teenager. I was going back to these foods I loved. So I guess there were kind of four things that happened. There were these three physical effects on my body. I gained a huge amount of weight and I wasn't force-feeding myself. And that really chimes with the epidemiological data that we have and from the clinical trial data run by Kevin Hall at the NIH, that this is food that gets around your body's evolved mechanisms that say, stop eating, you're full. Now the second thing that happened is we did some brain scans and I thought, well, the brain scan we're not going to see anything in a month of normal food.(05:43):So I switched from about 20% to 80% and we saw enormous changes in connectivity between the habit, automatic behavior bits at the back in the cerebellum and the reward addiction bits in the middle in the limbic system and associated regions. So that was very significant in me. And we did follow-up scans and those changes were robust and we really have no idea what is happening in children who are eating this stuff from birth to their brains, but it's concerning. And then the most intriguing thing was I ate a standard meal at the beginning of the diet and we measured my hormonal response to the food. And I think people are more and more familiar with some of these hormones because we've got drugs like semaglutide or wegovy that are interrupting these fullness or these hunger hormone pathways. And what we saw was that my hunger hormone response to a standard meal, my hunger hormones remain sky high at the end of the diet.(06:41):So this is food that is fiddling with your body's ability to say I'm done. But the most amazing thing was that this experience I had where the food became disgusting, there was this moment talking to a friend in Brazil called Fernanda Rabu. She's an incredible scientist, and she was the one who said, it's not food, Chris. It's an industrially produced edible substance. And I sat down that night to eat, I think it was a meal of fried chicken. And I was reading the ingredients and I could barely finish it. And so the invitation in my book is, please keep eating this food, read your ingredients lists and ask yourself why are you eating maltodextrin? What is it? Why are you eating xantham gum? What is diacetyl tartaric acid esters of monoglycerides of fatty acids? Why is that in your bread?Eric Topol (07:31):Yeah. Well, and then the other thing that the experiment brought out was the inflammatory response with the high C-reactive protein, fivefold leptin. So I mean, it really was extraordinary. Now the other thing that was fascinating is you have an identical twin. His name is, is it Xand?Christoffer van Tulleken (07:51):Zand, like Alexander,Eric Topol (07:53):JustChristoffer van Tulleken (07:53):The middle, full name's Alexander.Eric Topol (07:55):So spelled X, but okay, so he's an identical twin and he's up to 20 kilos heavier than you. So this helped you along with all the other research that you did in citations to understand the balance between genetics and environment with respect to how you gain weight. Is that right?Christoffer van Tulleken (08:16):That's right. So I have all the genetic risk factors for weight gain. And I know this because I've done studies with colleagues at the MRC unit at Cambridge, and I have all the polymorphisms, the little minor genetic changes that are very common. I have them all associated with weight. Now you can see I'm sitting here at the high end of healthy weight. I'm not thin, but I'm not. I'm just below overweight. And what protects me is my environment. And by that we mean my education, the amount of money I have, I have very little stress in my life. I have a supportive family. I have enough time to cook, I have a fridge, I have cutting boards, I have skills that I can do all that with. When my twin with this set of genetic risk factors moved to the states, he went to do a master's degree in Boston and he had a son in an unplanned way who's Julian is a much beloved member of the family, but it was very stressful.(09:15):What now? 13 years ago, and Zand kind of ate his problems, but the problems that he ate were ultra-processed food. So ultra-processed food, it's one of the ways in which the harms of poverty are expressed. So we know that people who live in stress and being poor is a significant source of stress. So it's disadvantaged. People generally smoke more, they drink more alcohol, they use gambling apps and they eat terrible food. And that is because of the environment they're in. It has nothing to do with their willpower or their choices. So part of the book is trying to reveal really that for many people, the food environment, the food that's available and they can afford is extremely violent to their bodies. And generally that's the environment of people who are already living with disadvantage.Eric Topol (10:06):Well, the data, which I wasn't fully familiar with, I have to say that you reviewed in the book, and then you may have seen in the British Medical Journal, there was a very good paper on ultra-processed food just published recently. I'm sure you know these folks. And not only does it review the point you made that 60% of the American diet and the UK diet is from ultra-processed food, but that all the analyses show 40% higher risk of type two diabetes, 35% risk of cardiovascular event, increased hypertension, 29% risk of all-cause mortality, 41% risk of abdominal obesity, metabolic syndrome, 81% higher risk. This isn't even yours. This is the review of all the literature, cardiovascular mortality, 50% higher risk. You mentioned the death from high U P F diet, 22% of all deaths. This is big. I mean, this is something I didn't realize. I knew it wasn't good, but I didn't realize the toll it was taking on the species. I mean, it's remarkable.Christoffer van Tulleken (11:17):It is in a sense, it's not enormously surprising. So the thing I think that is confusing a lot of people, there are two sort of sources of confusion. One is that the working definition that we all use is basically if something has an additive you don't find in a typical home kitchen, then it's an ultra-processed food. Now that has led a lot of people to go, well, the problem is the additives. Now, some of the additives, we think there's very good evidence they are causing harm. So the non-nutritive sweeteners, we had a huge paper come out and sell this summer. It's not referenced in the book, but the World Health Organization have written a position. And you may well know this literature better than me, but there's a growing concern that these products are definitely not better than sugar and they may predispose to metabolic disease and microbiome effects the emulsifier.(12:07):Again, we've got pretty good evidence that many of the synthetic emulsifies, and they are in everything. They're in your soda, your toothpaste, your bread, your mayonnaise. The emulsifiers are ubiquitous because they give a slimy mouthfeel that people like. So some of the additives are an issue, but the additives are just a proxy for food that is made with no regard for your health. And so a lot of the research I'm doing now is with economists. And so we're going to publish a paper in the next couple of months where one of the questions we've asked is, when it comes to the big transnational food corporations, is there good evidence within the corporations they care about human health? Because the companies that make this food say, we practice stakeholder capitalism, we care about the environment, we care about our farmers, we care about kids, people, our customers, we care about your health.(12:58):What we can show is that the way the companies spend their money is not to reinvest in those people, those stakeholders, they use it to buy shares back. So every quarter they do share buybacks to drive up equity value. We can show that when public health proposals reach the board or reach investors, institutional investors always vote down those public health proposals. And we have really good examples at Unilever, Pepsi and Dannon where CEOs have said, we want to make the food healthier and activist investors have fired the CEOs or fired the boards. So the companies are making the food with the purpose of generating money for institutional investors, usually pension funds. And so to me, it's not very surprising if you put yourself in the position of being a scientist at one of these companies or being a C E O and the market's saturated, we've all got enough food, you have to make food using the cheapest possible ingredients with the longest shelf life, and it has to be addictive or quasi addictive. That's the only way you can get us to buy more and more of it. And now that the states and the uk, Australia were saturated, they're starting to move very aggressively into south and Central America. I mean, they've largely done that, but now the focus is on West Africa, south Asia, east Asia, and Central Africa. So the purpose of the food, we call this system financialization, all the incentives in the system are financial. And so it's not surprising the food isn't very good for us.Eric Topol (14:31):And one thing I did like is that you did get into the companies involved here, and you also noted many times throughout the book about these scientists that said they didn't have any conflict and then turned out they had quite a lot of conflicts. And so one of the things I thought about while you mentioned about the transnational trans fats, trans fats were basically outlawed. And why can't we get, I think you touched on this in the chapter right before the end about we're just not going to be able to get these companies to change their ways, but why can't we get these U P Ss, particularly the ones that are most injurious? And by the way, you've proven that through three, not just the epidemiologic studies, which many people will argue diet logs are not so perfect, even though when it's in tens of thousands or hundreds of thousands of people. You mentioned, I wouldn't go back to the Kevin Hall experiments because he's really a noted researcher here in the US at NIH and also the biologic plausibility, which you've shown in spades throughout the book. But so with all this proof, why can't there be a path towards making these products, the ones that are the most implicated, illegal, and like the trans facts?Christoffer van Tulleken (15:56):So there are several answers to that. First of all, I guess my approach as an activist, and so I see in a kind of strange space because on the one hand I'm a scientist and I try and be fairly dispassionate. On the other hand, as you say, we now have very robust data. We've got more than a decade's worth. I mean, Kevin Hall sent a lovely tweet the other day, which I can unpack a bit, but this isn't argument basically between independent scientists and the industry and the industry are very, very skillful at mounting their arguments. So the argument of industry is, look, ultra-processed with the definition is wooly. It's not agreed on. These are largely observational studies. We need more randomized trials. The real problem with food, is it being high-fat, salt, sugar? And Kevin sent a brilliant tweet where it was in someone else where someone was going, look, why can't we just call it high-fat salt sugar?(16:52):What's processing got to do with anything? And Kevin said, well, look, no one has ever agreed on the definition of high-fat salt sugar. Whereas the definition of U P F is extremely widely agreed on, and we have now over a thousand studies linking it to negative health outcomes. So in terms of why we can't ban it, I guess my answer is I think it's politically extremely important not to frame it, not to frame things in terms of banning. If we want to see the gains that we got with smoking, my proposal is we need to regulate this food. We need to warden people, but we need to use the language of the political right and of the free market to get people on board. I want to increase everyone's choice in freedom. I don't want to take anywhere and cocoa pops or soda pop away.(17:36):It's fine if people want to buy that, but they should have a warning label on it and they should be able to buy fresh, affordable, healthy food. And what we know is that people like you and I, we will eat a bit of ultra-processed food, but broadly, people with resources don't eat this stuff. It's low income families that are forced to. So partly, I don't think we should be making it illegal, but the main reason is there is an enormous power. I mean, any one of these companies has the annual marketing budget that is maybe four or five times the entire World Health Organization operating budget each year. Okay, so we're talking 10 billion versus a couple of billion, and that's just for a company like Nestle or Danon or Coke. So the might of these corporations is overwhelming. And so the struggle will be very much as it was with tobacco.(18:30):And we have to be very careful how we sort of proceed and what we ask for. One of the issues that's going on at the moment is the definition of UPF at the moment is not suitable for legislation. So if we said, well, look, we are going to try and put a tax 10% tax on all UPF what will happen is the companies will have a lawsuit of every single additive. So they'll go, well, xantham gum is in kitchens actually, because we sell it in bags and people with celiac use it to bake at home. So then we have to have an exhausting discussion. So there's a group led by Barry Popkin and a number of other brilliant researchers who are creating a definition that it will include, I'm going to make this up, non-nutritive sweeteners, emulsifiers energy density and softness. And that will all with, we've got loads of randomized trials on all of that, and that will withstand the lawsuits. So it's about the technical approach has to be a very sophisticated one about resisting corporate power and the template has to be tobacco.Eric Topol (19:33):Yeah. Well, I think you've given a good response to those who would wonder, but the warning, as you know very well, far better than me, all we have on the foods are the nutrients of protein, carbohydrate, fat, saturated fat. There's nothing about warnings about the process. Ultra-processed content, which has to get fixed at some point in thatChristoffer van Tulleken (19:57):It has to, I mean, it is astound. What's going to happen is there are going to be lawsuits. So people are working on this and it's very hard to bring lawsuits around food, but one angle will be to focus on soda pop. So there should be a warning. And all the fizzy pop, it all contains phosphoric acid, which leeches minerals out of your bones, it dissolves your teeth, the sugar rots your teeth. And we will start to find communities that only drink one brand because there is a couple of very dominant brands, and they will be able to bring class action lawsuits about dental decay, and that's how it'll start. But in Argentina, in Chile, Columbia, they now on Cannes of cola do have big black hexagons. So it can be done. And I think the populations in the UK, obesity and diet related diseases reach such a crisis. People are so angry about this. And I think the people, the grassroots sentiment is I'm being gaslit by the people who sell my food. They've told me if I eat this, it'll help me lose weight. They've told me it will make me well, and it hasn't worked.Eric Topol (21:03):Yeah, well, that's for sure. Well, now I want to get into a couple of the things that shakes up the prevailing beliefs, the sacred cows, if you will. One of them is the burning calories with exercise. You really challenge that whole notion in the book, as I said, the book is not just about ultra-processed foods, which completely takes 'em apart, but you challenge the idea that you can work it off exercise, burn off these calories, and you have a pretty substantial part of the book that you really get into part help us understand because still today most people think, well, if I eat that such and such, I'll just exercise. I'll burn off those calories. What's the truth about that?Christoffer van Tulleken (21:56):So I wrote the book, I try to lay out the evidence for ultrapro food, but then you have to do some water battery because people always go, yeah, but isn't it because people who live with excess weight have low willpower, so I try and get rid of that. Or isn't it genetic? I can get rid of that. But a big argument is when it comes to the pandemic of obesity, surely it's because we spend all our lives on our phones, we sit around, we watch tv, and none of us work in heavy manufacturing anymore. So this idea was heavily promoted through a number of institutions, particularly something called the Global Energy Balance Network, and thousands of scientific papers in good robust peer reviewed journals. And some colleagues of mine at the London School of Hygiene and Tropical Medicines and Public health doctors did this incredible network analysis where they looked at the links between funding and all of these papers and all of the conferences that said, look, if you drink too much sugar or you eat too much chocolate, you just go for a run.(22:53):You burn off the calories, energy in energy out. Like it's simple. The entire network, and I really mean all of the papers, thousands of them were funded by the Coca-Cola Corporation. Now, in and of itself, that doesn't prove that it's a complete myth. But at the same time since the 1990s, there's been this real puzzling thing about our most sophisticated way of measuring energy expenditure using this technique called double labeled water. And there was this finding that no one could explain. It kept happening in all the studies in humans and in animals that people of the same size and shape and age and sex burn the same number of calories, whether they're subsistence farmers in Nigeria or secretarial workers in Chicago, whether they're hunter gatherers or office workers, everyone seems to burn the same 45 year old men who weigh 85 kilos like me. We can be hunter gatherers, we can be office-based doctors.(23:51):We burn the same number of calories. And a guy called Herman Ponsa pulled this together and he said, it seems like what is happening is that we have evolved to burn the same number of calories every day. Now, if you go for a run, you have to steal energy from other budgets. You can't violate the laws of physics. So if I burn 3000 calories today and I go for a 200 calorie run, I will take that 200 calories from my inflammation budget, from my anxiety budget, from my reproductive hormone budget. And that is why exercise is good for us. Now, what this doesn't mean is if you're cycling in the Tour de France, so you're an elite athlete or you're mountaineering, then you do burn more calories each day. And we've known that for a long time, but the kind of exercise that we all do each day, if we go to the gym a couple of times a week, that doesn't seem to affect our calorie expenditure. And the reason that, I mean, I'm an MD PhD, I feel I understand how the body works. I would say the reason I was unaware of that until I started writing the book and trying to figure out the piece of the puzzle I was missing is because of the Coca-Cola corporation. And there incredible network of edibles was network of literature that they funded.Eric Topol (25:01):Well, it shook me up because I was thinking all these years about, well, if I burned 500 calories, the other thing I thought about is I've had a knee operation replacement and I'm going to be immobilized and I'm going to get fat just because I can't exercise. And this was fascinating and you just reviewed it in a nutshell. It's really great for people to read that. Now, another one that you really took apart. So you and I both know Gary Taubes and I'm glad thatChristoffer van Tulleken (25:32):You had, and I want to say I love, I haven't spoken to him since the book, but I really, really love Gary. I think he's a brilliant guyEric Topol (25:40):And he has a new book that I blurbed about, not out yet on diabetes and all the lies about diabetes, but the book, he's been very influential as you know. And one of the things that he helped carry over the goal line and many others is this glycemic index and that the real reason we're fat is because we eat too much carbs and that it raises our insulin level and it makes us hungry. Basically, that's the simple dumbed down version and that he had been purporting that as the main driver of the obesity epidemic. You take issue with that, I would say, because you would say Uhuh maybe not so fast that UPFs are an important part of the story, and maybe it's not so simple as this glycemic index. Do I interpret that correctly?Christoffer van Tulleken (26:35):Yeah. So the sugar insulin debate is a long and exhausting one. And Gary, I would say, I mean he's a physicist by training and an incredible brain, and I think very few people have moved human nutrition further than Gary. Now, I would say the way he moved it is he got this incredible set of experiments funded, undertaken by Kevin Hall that really showed that there doesn't seem to be a particularly large difference between fat based diets or carb based diets in terms of how they affect your overall energy expenditure. And to some extent, it's not very interesting when we are talking about life out in the real world, there's a lab question about whether or not the carbohydrate insulin mechanism is really what's going on. And I would side kind of, I guess with Kevin Hall on that and said, I don't think the way you construct your diet in terms of its nutrients massively affects energy expenditure.(27:38):But in a sense, it's a bit moot because out in the real world, very few people are able to eat these ketogenic diets and stay on them. Some people are, a lot of people on the internet are, but kind of out in real life. We eat the food we're faced with. So I think sugar is very harmful in two ways. It rots teeth, and if you add sugar to food, you eat more of the food. And you can do this with any child at breakfast, you can give 'em a bowl of plain porridge and they won't eat much of it. You put two spoonfuls of sugar on it, they eat masses. Now, you haven't given them many more calories in terms of the sugar, but you've made something very appetite stimulating. So I think the crucial thing about all the research on U P F is it's all made adjustments for fat, salt, sugar, and fiber.(28:25):The big question for the epidemiologist has been are we sure this isn't just junk food that's high in fat, high in salt, high in sugar, and that's eaten by people who live in terrible housing and drink lots of alcohol and smoke lots. So the epidemiologists are very skillful at controlling for that. You can't control for everything. But what's consistent over all of the hundreds of prospective trials that we now have is that when you adjust for salt, fat, sugar, and fiber, not only does the effect remain in terms of statistical significance, it remains the same in terms of magnitude as well. And that backs up Kevin Hall's data where he had two, he randomized people to two equal diets nutritionally, same salt, fat, sugar, fiber, same deliciousness. People enjoyed the food the same amount. Both groups had as many calories as they could possibly eat, way more.(29:19):They have 5,000 calories a day, and yet the ones on the ultra-processed food, lost weight, sorry, on the unprocessed food, lost weight on the ultra-processed food gained weight. So I think what we may see is that when we go back and we redo some of the studies that link fat and sugar, and perhaps it may be salt, although I think salt is particularly in other ways, but when we do adjustments for ultra processing, we may see that the main driver of harm is when we encounter these molecules in formulations that we can't stop eating. So when we go and make the controls for ultra processing and we do the dietary analysis, we may see a dilution of the effect of fat and sugar.Eric Topol (30:02):So the people that swear, and there'll be many of them that listen or watch this, read this, they'll say, I went on a low carb diet and I lost all this weight. You would say, well, it wasn't just a low carb diet. There's a lot of other factors that come into play, including the fact that a lot of the carbs that you were eating are loaded with ups.Christoffer van Tulleken (30:27):Well, I think that's a great question. I would have two answers for those people. I'd say, well, that's great. And we know that many, if you eat any restrictive diet, so if you eat a low fat diet, a low carb diet, if you eat a diet based on avocados and breakfast cereal, many people will lose weight for some months. And particularly if you cut carbs out, food becomes much less palatable. Spaghetti bolognese is a lot less edible without the spaghetti. So we know that extreme keto diets, very low carb diets, they definitely work and they do help people lose weight. I don't think there's very good evidence that that's because of insulin suppression. I think it's because people eat fewer calories, because carbs make food delicious, and we just eat less of it.(31:18):And it may also be that when you cut out carbs, when you go on these diets, often you do switch away from industrially produced food that's very delicious, and you switch into, you become more conscious in other ways. So I think it definitely low carb diets help people lose weight. I'm not arguing that. I don't think it's to do with insulin, and I'm not sure they are. There's much evidence they're more effective than low fat diets, and there's very little evidence that anyone is any good at sticking to any diet for any period of time. Is that fair? I mean, I'm in your area now.Eric Topol (31:52):Yeah, no, no, that's a great explanation. A calorie is a calorie, and the diet, when you restrict it, it's going to have an effect at least on a short-term basis that is usually unsustainable over longer periods. I mean, this is, I think a shakeup. These are things in the book while you were directed towards the dissection of ultra-processed food and how our health is being adversely affected along the way. You take on a lot of these issues that people still, they are widely accepted. And that's what I especially enjoyed about the book is learning about your challenge of dogma. Some people when they watch this or listen to this, they're going to say, no, no, that can't be. And again, you're systematic. You quote the biologic plausibility studies, you quote randomized studies done by the likes of Kevin Hall. Well, let's talk about him in a moment. And then you get all these epidemiologic studies coming at everywhere. I mean, the hunt that you did on the research for this to find all these citations and review all them in itself was a tour to force.Christoffer van Tulleken (33:06):Whenever you open your mouth about food, you start an argument. And about 50% of the argument is the food industry who want the food industry wants us to believe the problem is with the nutrients because that's the thing they can fool around with. If sugar is the problem, they can take it out and put in the sweetness if that's the problem. They can put in xantham gum and gu gum and modified maize, starch and carrageenan. If salt's the problem, they'll put in potassium chloride. There's all kinds of stuff they can fool around with. They've been doing it since the early eighties and it hasn't worked. So the book is written in a kind of almost legalistic way. I mean, it has to be a legalistic, I mean, three teams of lawyers poured off the whole thing, but also I know I'm going to want people like you to read it, and I know it has to withstand your scrutiny.Eric Topol (33:57):It certainly has. I mean, what I love too is that in near one of the last chapters, you say, well, how are we going to get this on track? And you say The medical community, we as physicians caring for patients should be emphasizing this in our communication to patients. And I think that is one way a form of activism to take this on it, hopefully get it on track, largely been ignored. I mean, I think that the problem is because the food labels, even though people look at them, they don't read the fine print. That's where it shows up, if at all, and they're not familiar with the data incriminating all these things that shouldn't be in the food that are making it addictive and dangerous and whatnot. Yeah, I have to say, you have done a masterful job in reshaping my mind, which doesn't happen often when I read a book. I have to say it's just because what I admire is the depth of the citations backing it up. You're not a conspiracy theorist against the food industry. And I think you would be the first one to admit that Some people will say food science with air quotes because where's the science that a lot of the studies are garbage studies that are really questionableChristoffer van Tulleken (35:20):And the best science is done in industrial labs, and we don't have them too much access to it. I mean, I spoke, the most interesting community of people I spoke to for the book were people in the industry. They were all lovely. Many of them wouldn't be quoted, but they would explain how it was all done and behind closed doors, they all say, we know what we're doing. We know we are making addictive products. We've also got whistleblowers. And lots of people who have worked for engineer and people like Dana Small at Yale did lots of Pepsi funded research on the sweeteners. And when she published it all and said, look, I'm a bit worried about this, then Pepsi obviously stopped funding her. So yeah, I'm not a conspiracist and I'm also trying to make an argument. I'm not a neo-Marxist, not an anti-capitalist. We can imagine.(36:08):Part of the issue is in the states and in the uk, you are subsidizing the production of this food, and there is a whole industry and a whole set of businesses of people who make real food who could produce real food at a much more affordable cost. But instead what we do is we subsidize a very small number of agribusinesses to produce these commodity crops at the expense of the environment and our health, and then we pay less for the food in the shop, but we pay with our health insurance premiums and we pay with our environmental cost and we pay with our bodies as well. So this isn't really cheap food.Eric Topol (36:50):Well, that brings me to exacerbating preexisting inequities, which are far worse here in the US than many other countries, including yours. But the fact that there's these food deserts all over the place that the people can't get to, I mean the classification that a lot of people in the medical community are not familiar with the NOVA classification, the NOVA 1, the unprocessed or minimally processed food as opposed to what your book centered on the NOVA 4 ultra-processed food. But people in these desert food deserts can't get to the unprocessed NOVA 1 food and how can we get this righted because this is part of the problem is they're the ones at high risk and now their food that they're taking in is just making that even worse.Christoffer van Tulleken (37:47):I guess in my hierarchy of solutions, I have two things that need to be done before everything else. I believe that poverty is a political choice. There is huge amounts of money in both our countries and people. Children born into any household should be able to eat excellent, affordable food. So the number one thing is you have to fight poverty, that you don't need much redistribution. This isn't communism, it's not creeping socialism. It's just saying we could take a little bit of money out of the wealthiest corporations and individuals and lift a few people out of poverty. What we also know is when we do that, it's incredibly, so what's expensive is having an underclass of poor, unhealthy people in your society. So if you are a hawkish right-wing nationalist who wants a good football and a good military and low taxes, then for goodness sake don't have poor people living with terrible health problems.(38:42):It's ridiculously expensive. My interest is in social justice, I suppose, and I'm probably, I don't like to talk about my politics, but I'm a doctor working for the National Health Service. I treat patients with infections. So number one is poverty. The second thing you have to interrupt is the conflicts of interest. So in the UK, we had some headlines come out a couple of weeks ago, all the major papers published these headlines where five scientists had got together from something called the Science media center and said, look, ultra-processed foods are fine actually. And in fact, some of them are really healthy and you should eat brown bread and all this hysteria is nonsense. Now, when you looked at the five scientists, one of them had been the senior scientists at Nestle for 15 years. One of them was on the board of a multi-billion pound ultra-processed food company.(39:35):One of them had done research for the others and the institution, the science media center, very credible sounding. It's very, very popular in the UK with journalists. They always release press briefings. They're incredibly helpful. The Science media center is self-funded by Proctor and Gamble who make Pringles Nestle, who make Kit Katts and a consortium including Cargill and Coca-Cola. So none of the papers reported this apart from the Guardian did then run a brilliant story on the conflict. We have to see industry money as dirty. No one would accept the British Lung Foundation and their spokespeople taking money from Philip Morris and British American tobacco. We would all go, that's crazy. Well, the food industry are now doing this incredibly brilliant thing, which is exactly what the tobacco industry did, where they're doing this manufacturing doubt. So a lot of my time is spent trying to very carefully frame arguments in a way that is shored up against anyone thinking I'm trying to ban anything or take their fun away.Eric Topol (40:37):I love it. Have I missed anything that I should have asked you about? Because we've covered a lot of ground and I can't do justice to this book because it's a phenomenal book, and I hope that the people that are not just those who are worried about their own nutrition, but their loved ones, their patients, whatever, will get into this because you've got a lot of work here to offer to get people up to speed, educated about the problem. But is there anything else you can think of that you want to highlight?Christoffer van Tulleken (41:12):I think the only thing I try and underline, and you are always very skillful at this, but it's that I think one of the main harms for people who live with obesity and who live with diet related disease is stigma, particularly from our profession. We treat patients who live with obesity terribly badly. And the book, I hope, if it does, nothing else should try and show to any physician who reads it or any parent that when someone is living with any diet related disease, it really is not them. It is the food. We are saturated in products that we have, good evidence are addictive. They are all around us. And at the moment, our patients who are trying to lose weight, it's like them trying to quit smoking in the 1960s, you and I would be doing this interview smoking away, there'd be clouds of smoke everywhere my kids would be smoking. So that's the environment we're in. And I think if we can give people a break and try and try and not judge them and try and critique the system, that is the outcome that we need.Eric Topol (42:14):And here we are. We've got the GLP-1 drugs like Mounjaro and with Wegovy chasing the epidemic. And so we're using drugs, injectable drugs right now to chase something that is partly food mediated, I would say. And the other thingChristoffer van Tulleken (42:31):About those drugs that's so interesting is if you take the drug and you don't gain weight, but you continue eating the foods that drive other diseases, the effects where ultra-processed food seems to be associated with cancer, all cause mortality, dementia, anxiety, depression, cardiometabolic disease, that's when you adjust for obesity. So you don't have to gain the weight to have those effects. It's not that those things are caused by the weight gain, they're independently caused. And so you can be taking your Wegovy and you'll still have an elevated risk of cancer unless you change your diet. So these drugs are not going to get us out of the hole. They're going to be wonderful for some people who need to lose weight, but they're terribly expensive and they should not let the government off the hook of making sure that good food is available.Eric Topol (43:19):And then the other thing I wonder about, as you know, I work a lot in the AI space and I'm thinking these companies are going to increasingly use AI to make their addiction levels even higher because this is the way to understand how the proteins of the three D structures will bind better to parts of our receptors in our brain and whatnot. I mean, I'm worried that this could even get worse from these companies.Christoffer van Tulleken (43:50):It will definitely get worse. So I mean, the point you make is really important at the moment when we think about food addiction and was this brilliant paper was published the other day by Gerhart and Dili Santonio, two wonderful scientists, and they were drawing together a lot of different research showing that the food is addictive, whether you're scanning people or gathering psychiatric data. But the moment, the way we think about addiction is kind of these sugar fat ratios, but clearly it's so much more complex that when we add flavor acid, bitterness, sourness, all of these molecules, plus is exactly as you say, the food matrix, the texture, the smoothness, the fattiness, the packaging, the font animal that's there, the colors, all of it contributes to a sort of gestalt around each product that drives addiction. So yes, there is no question that the academic community has a very primitive understanding of how this food is driving excess consumption.(44:48):I suspect the companies know more, but mainly they've just been iterating it for decades. I mean, all the companies said the same thing to me. When they test food, they put it through a tasting panel, and one of the things they measure is how much do people eat and how quickly do they eat it? And if you've got two boxes of cereal, the one that people eat the quickest and the fastest is the one that goes on the shelf. And they've been doing this. You and I ate the same cereals as children, as my kids do. They've been perfecting them for five decades. And so it's not surprising that every single aspect of those cereals or the breads or the spreads, it's all dialed up to 11, whether it's the emulsifier, which one do you use? How much salt, the smoothness, glucose syrup, is it too sweet? A little bit more fructose? Our understanding is so primitive.Eric Topol (45:41):Well, your dissection of it is as comprehensive I could ever imagine from the speed that we eat to the texture and the softness and all the other things you just mentioned. So I want to congratulate you. This is, as I said at the top a masterpiece, and I'm really, we should be indebted to you for pulling it all together, and I look forward to further discussions with you because every time I eat now, I'm going to be thinking of you.Christoffer van Tulleken (46:10):I love it. I mean, Eric, I cannot tell you, I'm a long time admirer, so it is. Anyway, I'm not going to fanboy too much, but I can't tell you I'm deeply touched and very moved, and so I really appreciate you saying that.Eric Topol (46:22):Well, for you to volunteer to help on a Friday night late in the UK to do this, I'm indebted as well. So thanks so much, Chris. I look forward to talking to you much more in the future and really appreciate your joining today.Christoffer van Tulleken (46:36):I hope we'll speak again.Thanks for listening and subscribing to Ground Truths! Please share with your network if you found it useful. Thank you for reading Ground Truths. This post is public so feel free to share it. Get full access to Ground Truths at erictopol.substack.com/subscribe
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Dr. Sam Zand is a medical doctor and psychiatrist with a holistic approach to treating mental health conditions. He is the Chief Medical Officer of Better U, a company offering at-home ketamine therapy and holistic mental health programs. A few things we chat about in this episode
Today, Dr. Taz talks with Dr. Sam Zand, the Chief Medical Officer of Better U and a psychiatrist specializing in neuroplasticity. They explore the transformative potential of psychedelic medicine in addressing mental health issues and fostering new thought patterns. This episode highlights the evolution of mental health over the last decade, exploring why plant medicine, including psychedelics, has gained recognition as an effective form of treatment.Today on Super Woman Wellness: The transformative potential of psychedelic medicineThe evolving landscape of mental health over the past decadeImpact of nutrition on mental well-beingImportance of mindfulness practices in daily livingPlant medicine and integrative approaches to health This show is supported by:EastWest | Use code SWW30 to get 30% off at theeastwestway.com.Follow Dr. Sam Zand:Website: betterucare.com | drsamzand.comInstagram: @betterucare | @drsamzandFollow Dr Taz:Instagram: @drtazmdWebsite: doctortaz.com Pre-order The Hormone Shift book at prh.comthehormoneshiftThis show is produced by Soulfire Productions
Have you ever found yourself pondering the subtle indications that something might not be quite right in your relationships and dating experiences? Those cautionary yellow flags that discreetly wave, urging us to pay attention to underlying concerns as the relationship progresses. These yellow flags serve as early warnings, signaling that there is some essential work to be done within the relationship, and if left unattended, they may evolve into more pronounced red flags. In this thought-provoking episode, the insightful trio of TalkDoc, Meredith, and Teighlor embark on an engaging exploration of Yellow Flags in Relationships and Dating. Drawing upon the wisdom of renowned researcher John Gottman, they delve into the profound concept of the "four horsemen," which are destructive communication patterns that can erode the foundation of any relationship. By shining a light on these horsemen, they empower listeners to recognize and address potential pitfalls before they escalate. With compassion and expertise, our hosts carefully examine the wide array of warning signs that may manifest in relationships and dating scenarios. From subtle changes in behavior and communication patterns to a growing sense of emotional disconnect, they dissect the intricate tapestry of yellow flags, offering keen insights and practical strategies to navigate these treacherous waters. Moreover, this illuminating discussion delves into the pivotal question of when and why one might choose to terminate a relationship because of these warning signs. By exploring the delicate balance between self-preservation and relationship growth, our hosts provide listeners with invaluable guidance on recognizing the tipping point where the journey together becomes untenable. Tune in and join us for this pivotal and transformative conversation as we unravel the intricacies of Yellow Flags in Relationships and Dating. Gain a deeper understanding of these signals, learn to communicate effectively, and embrace the tools necessary for building healthy and thriving connections. Don't miss out on this essential episode that could reshape your approach to relationships and lead you towards a path of lasting fulfillment. Music by epidemic sound. SHOW NOTES: Experts : Dr. Nicole LePera, Dr. John Gottman, Dr. Zand, Dr. Jill Weber, Vanessa Trine Resources : https://www.gottman.com/ https://theholisticpsychologist.com/ https://www.forbes.com/health/mind/relationship-red-flags/ https://www.psychologytoday.com/us/blog/having-sex-wanting-intimacy/202206/5-ways-tell-its-time-relationship-end Links to Previous AFAF Episodes: Episode #061: Stop Criticizing! How to Properly Complain without Blame https://pod.link/afafwithtalkdoc/episode/af635ca774c6d2e6773cb13662cceeab Episode #002: Ah, Defensiveness - How to Manage Defensiveness https://pod.link/afafwithtalkdoc/episode/7006e63c9ed15961a921e4843f717078 Episode #064: AFAF Real Talk - Don't Be So Defensive! It's Me Not You! https://pod.link/afafwithtalkdoc/episode/c4d53cbcdc7bf08bf8a8e41c3abb9723 Episode #005: Shut Down Mode - How to Manage Stonewalling https://pod.link/afafwithtalkdoc/episode/100334e9de176a1fa5f53be4503458cf Episode #012: AFAF with Shardasia LeDay on How to Reconcile https://pod.link/afafwithtalkdoc/episode/fdae1ec8e31fb65c2c8cb34c429f148e Episode #062: AFAF with Vanessa Trine on Anxiety and How It Translates into the Body https://pod.link/afafwithtalkdoc/episode/0ea8856c22092ff47e49a366594e1a66
Red flags are warning signs that indicate potential problems and sometimes even dangerous situations in relationships. Red flags are easier to spot in other people's relationships than our own. Whether it is avoiding difficult conversations, frequently referencing former relationships, displaying inappropriate levels of emotion or other potentially dysfunctional behavior, red flags are important to identify and address. In this episode, TalkDoc, Teighlor, and Meredith identify red flags in relationships. We discuss common red flags and strategies for helping ourselves and others when they appear. Join us for this important conversation! Music by epidemic sound. SHOW NOTES: Experts : Kelman, Zand, Martin, Gillis, Samuels, Weber Resources : https://www.forbes.com/health/mind/relationship-red-flags/ https://psychcentral.com/blog/imperfect/2018/11/11-relationship-red-flags-and-why-we-ignore-them#Why-do-we-ignore-red-flags? https://www.kaytlyngillislcsw.com/ https://journals.ntu.ac.uk/index.php/litc/article/view/417 Links: Gaslighting Episode 23 (Part 1): https://pod.link/afafwithtalkdoc/episode/172b1da84e9ef9e99153bd3d3622698b Gaslighting Episode 24 (Part 2): https://pod.link/afafwithtalkdoc/episode/3a5b4efae31991c46b80678dfad86f9f National Domestic Violence Hotline The National Domestic Violence Hotline (USA) at 1-800-799-7233, or National Domestic Violence Helpline (UK) at 0808 2000 247 Above all else, know that you deserve a safe, healthy relationship. If you're experiencing any form of relationship abuse, you can reach the National Domestic Violence Hotline 24 hours a day, seven days a week by calling 1-800-799-SAFE, texting START to 88788, or messaging a real person via live chat at thehotline.org “We accept the love we think we deserve” - The Perks of Being a Wallflower
Is Ketamine better than antidepressants? Could ketamine be the future for depression treatment. Research proposes that a combination of treatments serves depression outcomes best, but with only 10-30% of patients prescribed antidepressants experiencing Benefit from their medication, he proposes an alternative. By discovering neuro plastic therapy, he discusses the role of psychedelics treating depression and how it differs from anti depressants and talk therapy. Aclnowledging the importance of professional administration, he speaks to how recreational use can set individuals back and how appropriate guidance can be liberating for depression patients. Finally, he explains psychedelic use after therapy, navigating bad experiences with Ketamine and how to come back, recommendations for those with previous addictions, microdosing Ketamine, and how ketamine could be used as a chronic pain treatment. LMNT Electrolyte Discount: Fuel every system within the body and the brain with LMNT! Keep yourself hydrated on a cellular level by replenishing the sodium, potassium and magnesium that our body needs for basic cellular processes like nerve signalling, smooth muscle contractions, unnecessary fatigue, aches and pain, brain fog, and recovery! Get a free gift with every purchase and try some new flavours as you stay hydrated! (affiliate link) What You Will Learn In This Interview with Dr. Sam Zant 01:20 - Neuro Plastic Therapy 05:43 - What attracted Dr. Zant to the field of psychedelics? 08:52 - Do psychedelics work in combination with antidepressants or alone? 10:46 - Ketamine therapy vs antidepressant vs talk therpay for neuroplasticity therapy 15:46 - Psychadelic recreational use vs professional administration 17:30 - Ending therapy - do patients need to continue psychedelic use afterwards? 20:33 - Navigating bad experiences with psychedelics 22:51 - Recommendations for those with previous addictions 25:07- Using psychedelics to treat chronic pain? 29:31- Microdosing Ketamine & what people gain. 32:00 - Learn more with Dr. Sam Zant To learn more about Dr. Sam Zant and view full show notes, please visit the full website here: https://www.docjenfit.com/podcast/episode303/ Thank you so much for checking out this episode of The Optimal Body Podcast. If you haven't done so already, please take a minute to subscribe and leave a quick rating and review of the show! --- Send in a voice message: https://podcasters.spotify.com/pod/show/tobpodcast/message
We are so excited to welcome the incredibly insightful Dr. Sam Zand & Derek Du Chesne, founders of Better U—a holistic approach to mental wellness through psychedelic therapy. We uncover the benefits of ketamine therapy, the potential risk of psychedelic medicine, neuroplasticity, Better U's mission, the future of this field, + much more. Is ketamine therapy something you can see yourself trying?ALL THINGS BETTER U, DR. SAM ZAND, AND DEREK DU CHESNE!https://www.betterucare.com/https://www.instagram.com/drsamzand/https://www.instagram.com/derekddd/SHOP “CO-CREATE” TMV'S MANIFESTATION JOURNAL: https://www.thoughtsmayvary.com/the-tmv-shopDiscount codes, extra unpackings, journal prompts, vlogging (+more!) all happening with our familia over on Patreon. Come hang out — https://www.patreon.com/thoughtsmayvaryDon't forget to DM us on IG or submit a question on thoughtsmayvary.com to have your question or theme unpacked on a future episode!
پادشاهی با پایتخت شیراز در دوران نسبتا آرام ایران که دنبال تاج و تخت و عنوان شاهی نبود. متن: علی بندری | ویدیو و صدا: نیما خالدیکیا برای دیدن ویدیوی این اپیزود اگر ایران هستید ویپیان بزنید و روی لینک زیر کلیک کنید یوتیوب بیپلاس کانال تلگرام بیپلاس منابع: Karim Khan Zand (Mohammad) Karin Khan Zand کتاب تاریخ مدرن ایران - عباس امانت The Afghan Interlude and the Zand and Afshar Dynasties
Knowledge Bomb: Dr. G goes into what is healing Post Traumatic Stress Disorder (PTSD). What is MDMA? How was it used in the beginning? What are the studies showing with MDMA and PTSD? What is the safety of using MDMA for PTSD? Will it be available in the near future? Special guest segment: Founders of Better U, Dr. Sam Zand and Derek Du Chesne join the show to talk about the state of mental health. Is a mental health diagnosis helpful or detrimental? How are we overlooking what heals mental health? Do psychedelics have a role in healing mental health? How is ketamine used for mental health? How has conventional medicine missed the boat on treating mental health disorders? What is the future of mental healing? Visit link below https://trk.chilisleep.com/SHA7 And use the code DRG15 for 15% off the new Dock Pro Sleep System and DRG30 for 30% off a full OOLER, CUBE, and chiliBLANKET sleep system. These offers are available exclusively for Dr. G listeners. Become the best version of yourself and get 15% off Ned products with code DRG. Go to https://helloned.com/DRG or enter code DRG at checkout. To make it easy, Athletic Greens is going to give you a FREE 1 year supply of immune-supporting Vitamin D AND 5 FREE travel packs with your first purchase. All you have to do is visit athleticgreens.com/healthyself. Be sure to like and subscribe to #HealThySelf Hosted by Doctor Christian Gonzalez N.D. Follow Doctor G on Instagram @doctor.gonzalez https://www.instagram.com/doctor.gonzalez/