Podcasts about lactobacilli

High Fructose Corn Syrup's Profits over Health:  Richard Gale & Gary Null PhD Progressive Radio Network, July 24, 2024 There is an unseen culprit hiding in the shadows. It is a toxic poison contained in many of the foods and beverages that we commonly eat. A toxin that has been implicated in causing cancer, diabetes, heart disease, lowered cognitive function, addiction, depression, and obesity. The magicians and alchemists of the corporate food industry have cleverly disguised this ingredient and sing its praises.  If you are waiting for mainstream media to undertake an in-depth investigative report on this topic you will be waiting a long time. Back in 2015 Tufts University's department of nutritional sciences conducted a study published by the American Heart Association that documented the annual rates of global deaths directly due to over-consumption of beverages with high sugar content. The results estimated that 184,000 adults die annually from sugary drinks.  Dr. Gitanjali at Tufts analyzed data documenting sugar-related deaths across 51 countries between 1980 and 2010.  Deaths were compiled according to cardiovascular disease, diabetes and various cancers. Based upon the data, the study concluded that sugar contributed to 45,000 annual deaths from cardiovascular disease, 13,000 deaths from diabetic complications, and 6,450 deaths related to cancer.  Credit Suisse's Research Institute published a scathing report that brought sugar's health risks into sharper focus.  The study revealed that upward to 40% of American healthcare expenditures could be directly tied to overconsumption of sugar in the average American diet.  Today, the US' national addiction to sugar contributes to $1 trillion in healthcare costs annually, which includes coronary heart disease, diabetes and metabolic syndrome. There are numerous studies published in reliable peer-reviewed medical journals associating sugar with each of these life threatening diseases. As far back as 1971, I began writing about the hazards of sugar. In 2002, my documentary Seven Steps to Perfect Health was premiered on PBS stations. During a special appearance on one station's fund drive, I poured sugar out of a bag. The amount I poured equaled the number of teaspoons that an average American teenager consumes daily. My general counsel, David Slater, verified the quantity by proper measurement according to scientific food and diet data.  After the initial airing of this special, I was informed by the station's program director that they could not rebroadcast the performance, even though it was the most successful program during the fund drive. I was informed that the station had received harsh criticism from the sugar industry. The program director explained that the information I presented about sugar's dangers, even though I provided full scientific verification of the facts, ran up against the president of the station board Sharon Rockefeller. I was told she had received a phone call from a sugar-lobbying group representing soft drink makers and sugar manufacturers.  Therefore the station made the decision to pull my program. I was never asked to return to the station. Not surprisingly, a subsequent investigation revealed Sharon Rockefeller sat on Pepsi's board at the time, one of America's largest manufacturers of sweetened soft drinks.    That was my first personal encounter with the political forces supporting sugar. I wrote letters to the sugar industry, the station board and Sharon Rockefeller contesting their suppression of my program and their claim that sugar was unrelated to the declining health of Americans. They were presented with dozens of peer-reviewed studies. However in recent decades, the sweetener industry has undergone a dramatic transformation with the introduction and widespread adoption of high fructose corn syrup (HFCS) throughout our food system. This shift from traditional cane sugar, which dominated my criticism earlier, to fructose corn sugars has led to deep human health and environmental concerns due to its economic benefits for food manufacturers.  High fructose corn syrup was developed in the late 1960s by Japanese scientists who discovered a method to convert glucose from cornstarch into fructose using enzymes. This innovation was spurred by the need to find a cheaper and more versatile sweetener as an alternative to the more labor-intensive production of traditional cane sugar. HFCS is made by milling corn to produce cornstarch. The starch is then hydrolyzed into glucose by adding the enzyme alpha-amylase. Finally the glucose is further processed into fructose. The result is a syrup that typically contains 42-55 percent fructose, with the rest being glucose. Some methods can produce fructose as high as 90 percent.  Today, HFCS production has been so optimized that it has become the most cost-effective and efficient means to produce sweeteners. Monsanto's genetically modified Round-Up Ready corn, enabling the use of more toxic herbicides and pesticides, has now made HFCS the cornerstone of the sugar industry.  However, the shift to HFCS has been fundamentally driven by economics and the agro-chemical industry and has absolutely nothing to do with creating a healthier sugar.  Since corn is one of the most extensively cultivated crops in the United States, which is heavily subsidized by the government, it has provided an enormous, inexpensive supply of the raw material needed for HFCS production. In addition, the enzymatic conversion process can result in a high yield of sweetener from a relatively small amount of corn.  HFCS is now a ubiquitous ingredient that permeates our entire modern food supply. Starting in the 1980s, the introduction of HFCS has gradually displaced traditional sweeteners such as natural cane sugar, glucose and honey. According to the USDA, HFCS can cost up to 50% less than cane and other traditional sugars. This cost differential is particularly significant in industries where sweeteners constitute a major portion of production costs such as in soft drinks, artificial fruit juices, sweet baked goods, snack foods and candy, breakfast cereals, condiments and sauces, sweetened dairy products such as yoghurt and ice cream, and a large variety of processed canned and prepared meals. A study published in American Journal of Clinical Nutrition found that HFCS accounts for over 40% increase of caloric sweeteners added to foods and beverages. Having a purview of the distribution of different sugars in the American diet helps to illustrate the dominance of HFCS in the food system. Approximately 45 percent of added sugars in the American diet come from HFCS and an additional 2 percent from pure fructose. Between 35-40 percent of sweeteners derive from sucrose, the common table sugar made from sugarcane and sugar beets -- the latter now being genetically modified. The production process involves crushing the plant material to extract the juice, which is then purified, concentrated, and crystallized to produce table sugar.  Not to be confused with HFCS, corn syrup is largely glucose and represents about 10-15 percent of the nation's sugar intake. It is the most common sugar used in baked goods and candy. Lactose and galactose each account for about 4-5 percent of consumed sugars. However they are typically not added sugars to foods but naturally present in all dairy products.  Finally, honey, which at one time was a common food ingredient, today only accounts for about 1-2 percent of sweeteners.  Moreover, according to FDA testing, a lot of commercial honey found in grocery stores has been adulterated with HFCS and other sweeteners, such sucrose derived from cane and GMO beet sugars and artificial honey-flavored imitators.  A general estimate is that 20-30 percent of honey sold is impure.  Back in the 1970s and 1980s when I frequently railed publicly against the sugar industry and the health risks of processed table sugar that then completely dominated the food industry, I would never have imagined that sucrose would be gradually replaced by HFCS. This replacement accelerated after the emergence of genetically modified (GM) corn. As noted above, the vast majority of HFCS produced in the United States, the world's larger corn producer globally, is derived from genetically modified (GM) corn. Estimates suggest that around 85-90% of the corn grown in the U.S. is genetically modified. Therefore it is reasonable to infer that approximately 85-90% of HFCS is derived from GM corn. As many court cases and exposes of corruption in the agro-chemical industry have cone to light, GM corn has dire implications for the production and consumption of HFCS, especially considering the associated health risks linked to the use of toxic herbicides such as glyphosate. Research has linked glyphosate to various health issues, including cancer. A decade ago, the International Agency for Research on Cancer (IARC) classified glyphosate as a "probable human carcinogen"; today, it is no longer probable but a medical fact. Several studies have detected glyphosate residues in food products containing HFCS. A study published in Environmental Health found glyphosate residues in a variety of food products, highlighting the widespread contamination of the food supply with this herbicide. In addition to glyphosate's carcinogenic potential, the toxin has also been shown to disrupt endocrine function and it has been implicated in gut dysbiosis, an imbalance in the gut microbiome. This disruption can lead to a range of health problems, including inflammatory bowel disease (IBD) and other gastrointestinal disorders. Research published in Current Microbiology indicates that glyphosate exposure can alter the composition of the gut microbiota, leading to adverse health outcomes. HFCS and traditional sugars like table sugar differ significantly in their composition and metabolic effects. Sucrose is a disaccharide composed of equal parts glucose and fructose, while HFCS is a mixture of free glucose and fructose, with the fructose content higher than that in sucrose. This difference in composition affects how the body metabolizes these sugars. Briefly, HFCS poses more serious health risks than sucrose. The free fructose in HFCS is absorbed more rapidly than the bound fructose in sucrose, leading to quicker spikes in blood sugar and insulin levels. In addition, the high fructose content in HFCS places a greater burden on the liver, leading to increased fat production and storage, contributing to fatty liver disease and metabolic disorders. In contrast, the balanced glucose-fructose composition of sucrose is metabolized more evenly, posing lower risks. However, it is crucial to realize that excessive or even moderate consumption of any form of sugar can be detrimental to health. Extensive research has linked the consumption of HFCS to a range of adverse health effects. Key among these is metabolic disorders and cardiovascular diseases. A study published in the Journal of Clinical Endocrinology & Metabolism found that high consumption of HFCS is associated with an increased risk of developing metabolic syndrome, which includes conditions such as obesity, insulin resistance, hypertension, and dyslipidemia. These conditions collectively elevate the risk of heart disease and stroke. HFCS has been directly implicated in America's obesity epidemic due to its high fructose content, which is metabolized differently than glucose. Fructose is primarily processed in the liver, where it can be converted into fat more readily than glucose. This process can lead to increased fat accumulation and insulin resistance, both of which are risk factors for obesity and type 2 diabetes. A study in the American Journal of Clinical Nutrition highlighted that high HFCS consumption is correlated with an increased risk of obesity and diabetes, particularly in children and adolescents. HFCS intake also leads to non-alcoholic fatty liver disease (NAFLD). Unlike glucose, which is metabolized by all cells in the body, fructose is metabolized almost entirely in the liver. High levels of fructose overwhelms the liver's capacity to process it, leading to fat accumulation and liver damage. Research published in Hepatology has shown a strong correlation between HFCS consumption and the progression to more severe liver diseases, such as cirrhosis and liver cancer. Recent evidence reveals that HFCS has detrimental effects on cognitive function and mental health. Studies indicate that fructose impairs insulin signaling in the brain, which is crucial for maintaining cognitive functions. A study in the Journal of Physiology found that high-fructose diets can lead to insulin resistance in the brain, potentially increasing the risk of neurodegenerative diseases like Alzheimer's. Additionally, high sugar diets, including those high in HFCS, have been linked to mood disorders, such as depression and anxiety, as detailed in a review in Nature Reviews Neuroscience. HFCS and other fructose-rich sugars can have profound adverse effects on the gut and digestive system. These sugars are known to disrupt the normal functioning of the gastrointestinal tract, contributing to various digestive disorders and altering the gut microbiome. Fructose, unlike glucose, is not directly absorbed by the body. It requires a specific transporter, GLUT5, to be taken up by the intestinal cells. Fructose interferes with these transporters, leading to malabsorption. Unabsorbed fructose travels to the large intestine, where it undergoes fermentation by gut bacteria. This process produces gases such as hydrogen, carbon dioxide, and methane, which cause bloating, gas, and abdominal pain leading to malabsorption and the intestine's inability to absorb fructose efficiently. The gut microbiome, a complex community of trillions of microorganisms living in the digestive tract, is crucial for maintaining digestive health, immune function, and overall well-being. High intake of fructose negatively affects this delicate balance. Studies have shown that diets high in fructose can lead to an imbalance in the gut microbiota composition. This imbalance is characterized by a decrease in beneficial bacteria such as Bifidobacteria and Lactobacilli and an increase in harmful bacteria like Clostridia and Enterobacteria.  A study published in The American Journal of Clinical Nutrition found that high fructose levels increase intestinal permeability, also known as "leaky gut." This condition allows harmful substances, such as toxins and bacteria, to pass from the gut into the bloodstream, triggering inflammation and contributing to the development of various diseases, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). Inflammatory bowel disease, which includes conditions like Crohn's disease and ulcerative colitis, is exacerbated by promoting inflammation and altering the gut microbiota. A study in the journal Gut reported that reducing fructose intake improved symptoms in individuals with IBS, suggesting a direct link between fructose consumption and IBS symptom severity. Finally we need to also consider the catastrophic effects of HFCS on children. Children are particularly vulnerable to the health risks associated with HFCS due to their higher consumption levels relative to their body weight. According to data from the CDC, the average American child consumes approximately 12-16 teaspoons of added sugars per day, a significant portion of which comes from HFCS. This high intake is largely driven by the consumption of sweetened beverages, snacks, and processed foods that are marketed specifically to children. The high consumption of HFCS among children is a major contributor to the rising rates of childhood obesity and metabolic disorders. Studies have shown that children who consume high levels of sugary beverages and snacks are more likely to develop obesity, insulin resistance, and type 2 diabetes. A study published in Pediatrics found that children who consume sugary drinks daily are at a significantly higher risk of developing obesity compared to those who consume them less frequently. There is also growing concern about the impact of HFCS on children's cognitive development and behavior. High sugar diets have been linked to attention deficit hyperactivity disorder (ADHD) and other behavioral issues in children. A study in the Journal of Attention Disorders found that excessive sugar consumption, including HFCS, exacerbates symptoms of ADHD and impair cognitive functions such as memory and learning. A deeper look at the politics of the sugar industry reveals that huge sums are being doled out by the government to support and subsidize sugar companies. Writing for the Wall Street Journal, health journalist Alexandra Wexler explains that American taxpayers are currently responsible for shelling out $280 million to cover the cost of loans from the USDA which sugar producers are unable to pay back. Given the undeniable evidence demonstrating the toxicity of HFCS and other commercial sugars and their enormous toll on the wellbeing of Americans, why is it that our health agencies and elected officials are not calling for an urgent overhaul of existing policies, which graciously support the domestic sugar industry to poison the population? Where is the outrage over bailing out the purveyors of what is likely the most dangerous staple in the American diet? For our answers we must follow the money-trail.

In this episode, we dive into the fascinating world of prebiotics and probiotics, with a special focus on the trendy probiotic sodas that are taking the market by storm. Join us as we explore the definitions, benefits, and practical applications of these gut health powerhouses. Learn how incorporating these elements into your diet can enhance your digestive health, boost your immune system, improve your mental well-being, and aid in weight management. Key Points Discussed: Definition of Prebiotics and Probiotics: Prebiotics: Non-digestible food components that promote the growth of beneficial microorganisms in the intestines. Probiotics: Live beneficial bacteria naturally found in fermented foods and supplements. How Prebiotics Work: Examples of Prebiotic Foods: Garlic, onions, bananas, asparagus, whole grains. Mechanism: Prebiotics feed and promote the growth of healthy bacteria in the gut. How Probiotics Work: Examples of Probiotic Foods: Yogurt, kefir, sauerkraut, kimchi. Mechanism: Probiotics add beneficial bacteria to the gut microbiome. Importance of Gut Health: Gut Microbiome Overview: Brief overview of the gut microbiome and its impact on overall health. Digestive Health: Improved digestion, prevention of diarrhea, and relief from irritable bowel syndrome (IBS). Immune System: Enhanced immune response and reduced risk of infections. Mental Health: Potential effects on reducing symptoms of anxiety and depression. Weight Management: Role in maintaining a healthy weight. How to Incorporate Them Into Your Diet: Practical Tips: Adding prebiotic and probiotic foods to daily meals. Supplement Recommendations: How to choose supplements if necessary. Research on Prebiotic Beverages: Gut Microbiota Enhancement: Prebiotic beverages promote the growth of beneficial gut bacteria like Bifidobacteria and Lactobacilli, improving digestion and reducing gastrointestinal issues. Immune System Support: Prebiotic beverages enhance the immune response and reduce the incidence and duration of common colds and respiratory infections. Appetite Regulation: Consumption of prebiotic beverages can help regulate appetite and support weight control by lowering levels of the hunger hormone ghrelin. Mental Health Benefits: Prebiotic consumption can reduce anxiety and improve mood through the production of short-chain fatty acids (SCFAs) and modulation of neurotransmitter levels. Caution: Consuming more than 30 grams of prebiotics may increase inflammation. It's essential to listen to your body and adjust intake accordingly. Practical Advice on Prebiotic Beverages: Supplement Form: Consider supplements like Sunfiber, which can be added to beverages such as Polar Joe. Considerations for Kids: Monitor the amount of prebiotics to avoid overconsumption. Biofeedback: Pay attention to your body's responses and adjust your diet as needed. Conclusion: Prebiotic and probiotic foods and beverages are a convenient and effective way to boost gut health and overall well-being. With ongoing research, we continue to uncover the long-term benefits and optimal ways to incorporate these elements into our daily lives. Want to learn more? Tune into the FREE Biofeedback Boss Workshop!  Cheers, and happy eating!  Jess 

Here are the notes for episode #476 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle and Stef discuss protein timing, metabolic eating, and sleeping when under stress.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[19:28] Protein Timing[25:36] Metabolic Eating[36:58] Sleeping When Under StressLinksAbercrombie Bodysuit: https://rstyle.me/+-zhzmpS04ItCUL7uLTHGdQProtein Timing Research: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924200/https://www.instagram.com/reel/C3GeyxJu6sV/?igsh=ZDVhOXBhYnpyYnVxhttps://www.consumerreports.org/health/food-contaminants/the-plastic-chemicals-hiding-in-your-food-a7358224781https://www.instagram.com/reel/C2SZiIXucET/?igsh=bm02ZGpnZGRxZmduMD LogicDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.BlissyBlissy sells 100% mulberry silk pillowcases that are naturally hypoallergenic, cooling, and unlike other silk pillowcases, Blissy's are machine washable and durable.Blissy has a ton of different prints and colors and they make great gifts because there's an option for literally anyone.Try now risk-free for 60 nights, at Blissy.com/WELLFED and get an additional 30% off with our special code WELLFED.

Here are the notes for episode #474 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle and Stef discuss protein myths, maintaining muscle during stress, and staying motivated. Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[25:27] Protein Myths[41:13] Maintaining Muscle During Stress[51:40] Staying MotivatedLinkshttps://coconutsandkettlebells.com/proteinprepStanley potential lawsuit: https://www.forbes.com/sites/jamesfarrell/2024/02/21/maker-of-popular-stanley-cups-faces-lawsuits-over-lead-in-cups-heres-what-to-know/?sh=59852646e424Stanley cups lead in the bottom: https://www.instagram.com/reel/C2xMSz_uRfL/?igsh=YmNsbjJ5aXRlY25kLMNTThis podcast is sponsored by LMNT! LMNT makes grab and go electrolyte replacement supplementation. You just take an LMNT recharge packet, mix it up with water, and sip! There's absolutely no sugar, gluten, fillers, artificial ingredients, and it's paleo friendly.LMNT's co-founder is actually Robb Wolf, who we interviewed on episode #311, so you know the ingredients are solid and it's been well researched and developed.To grab a FREE sample pack of LMNT, go to drinkLMNT.com/wellfed, all you'll have to do is pay for shipping. It's so worth it, and you'll get to test it out extensively! That's drinkLMNT.com/wellfed. Click “get yours” and then grab yourself some packets to have on hand!Dr's ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.

THROWBACK EPISODE: What is vaginal hygiene, and how much is too much? Should you wax or shave? What are best practices for keeping it clean and healthy down there? What are common misconceptions women have about vaginal smell? Join us for this episode of Wellness Wednesday as we discuss caring for the "vaginal ecosystem" with our nurse practitioner, Christi!   Resources from our provider: Daily Vaginal Microbiota Fluctuations Associated with Natural Hormonal Cycle, Contraceptives, Diet, and Exercise (nih.gov) The Vaginal Microenvironment: The Physiologic Role of Lactobacilli (nih.gov)   Disclaimer: The information shared in this podcast is the opinion of the speaker, or speakers. Medical information is not intended as individual medical consultation, but for general education only. Always consult your own health professional for personalized advice regarding medical decisions.

Welcome to our podcast on "The Science Behind The Oral Health Probiotic from Bristle Health." In today's episode, we explore the research and clinical studies backing Bristle's unique oral probiotic formulation. Join us as we uncover and discuss how these probiotics revolutionize oral healthcare by balancing the oral microbiome, the specific strains used in this product, the benefits they offer and how they combat common dental issues. Key Takeaways:-Innovative Approach: Bristle's Oral Health Probiotic represents a cutting-edge approach in oral healthcare, focusing on balancing the oral microbiome for better overall oral health.-Six Key Strains: The product contains six clinically proven probiotic strains - Streptococcus salivarius M18, Streptococcus salivarius K12, Lactobacillus reuteri, Lactobacillus salivarius, Lactobacillus plantarum, and Bifidobacterium lactis - each with a specific role in improving oral health.-Clinical Backing: Each strain included in the probiotic has been backed by clinical studies and research, demonstrating their efficacy in reducing gum inflammation, combatting tooth decay, and fighting bad breath.-Natural and Safe Ingredients: The probiotic is made with natural ingredients, including xylitol instead of sugar, making it a safer and more effective option for oral health maintenance.-Usage Recommendations: For best results, the probiotic should be used once daily for general oral health maintenance and twice daily for addressing specific oral health issues like gum disease and bad breath.Book a consultation today:I am always here to help answer any question and schedule a 15 minute call with me. If I can not help, I can get you to a provider that can.https://shereewertz.com/15-min References:Journal of Applied Microbiology: “A preliminary study of the effect of probiotic Streptococcus salivarius K12 on oral malodour parameters.”Journal of Breath Research: “Oral probiotics reduce halitosis in patients wearing orthodontic braces: a randomized, triple-blind, placebo-controlled trial.”Journal of Oral Microbiology: “Effect of the probiotic Lactobacilli reuteri (Prodentis) in the management of periodontal disease: a preliminary randomized clinical trial.”BMC Oral Health: “Effects of Lactobacillus salivarius-containing tablets on caries risk factors: a randomized open-label clinical trial.”Journal of Clinical Periodontology: “Clinical and microbiological effects of the adjunctive use of probiotics in the treatment of gingivitis.”

OK, we knew the human gut had one of these, but the vagina too? What's actually going on in there? Microbiomes are incredibly diverse ecosystems: we are more bacteria than we are human. Yep. Read that again — there are more bacteria in us than human cells. You, my friend, are a moving, breathing microcosm that is incredibly cooperative when you're healthy. Don't panic. Katy Bradbury is back to explain what all this means and how we can use this knowledge to be healthier. Things to know: A healthy gut is NOT free from bacteria. We need the friendly bacteria to survive. Yes, it's a bit icky to think about, but it's important.  “Bad” bacteria is opportunistic, like weeds in a garden, says Katy. You need to keep your “good bacteria” healthy and plentiful so the bad can't get a foothold. We want a diversity of good bacteria in both the gut and the vagina, but these are not the same critters. Lactobacilli are best for the vagina, so knowing how to protect lactobacilli by keeping the vaginal environment at the right pH is a good thing. This is important for fertility but also for avoiding infections like yeast infections and UTIs, so care is a life-long need. Douching and using other “cleaning products” is NOT vaginal care unless you have a specific medical reason. These products disrupt the natural vaginal pH and aren't necessary for this self-cleaning organ. There's so much good information in this episode, so please give it a listen and share with others. While it may be difficult to overcome the traditional shame around our bodies, this shame is, frankly, not helpful. Sharing information and talking openly are the best way to erase the shame and be healthier. Ready to learn more? Listen up! More about Katy Bradbury: Katy is founding member of the Fertility Nutrition Centre, a clinical advisor at Fab Fertile, a content provider for women's health platform Xena, and a clinical supervisor for nutritional therapy students at the University of West London. You can find her at Katy Bradbury.com. Be sure to check out the robust back catalog of episodes from her podcast Fertility and the First 1000 Days: katybradbury.com/podcast To hear more from Anne and Ruby, find all their episodes at thewholepineapple.com.

The Science, Microbes & Health Podcast  This podcast covers emerging topics and challenges in the science of probiotics, prebiotics, synbiotics, postbiotics and fermented foods. This is the podcast of The International Scientific Association for Probiotics and Prebiotics (ISAPP), a nonprofit scientific organization dedicated to advancing the science of these fields. Lactobacilli in the microbiomes of […] The post Episode 28: Lactobacilli in the microbiomes of the gut, skin, reproductive tract and more appeared first on International Scientific Association for Probiotics and Prebiotics (ISAPP).

Here are the notes for episode #443 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle and Stef discuss dieting for weight loss, high stress seasons, and controlling your kids' food.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[13:18] Dieting for Weight Loss[32:45] High Stress Seasons[57:40] Controlling Your Kids' FoodsLinksBoundaries Book: https://rstyle.me/+sTrajMRUdRfNNOqVuyJGYAThe Ruthless Elimination of Hurry: https://rstyle.me/+4chHnlsym_j5t_nwmnZgXABlissyBlissy sells 100% mulberry silk pillowcases that are naturally hypoallergenic, cooling, and unlike other silk pillowcases, Blissy's are machine washable and durable.Blissy has a ton of different prints and colors and they make great gifts because there's an option for literally anyone.Try now risk-free for 60 nights, at Blissy.com/WELLFED and get an additional 30% off with our special code WELLFED.Dr.'s ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.Bon ChargeBON CHARGE is a holistic wellness brand with a HUGE range of evidence-based products to optimize your life in every way, including their NEW sauna blankets.Far infrared light works by heating the body up directly, which speeds up your metabolism and sweat rate. It also relaxes muscles and reduces muscle tension, and I've already noticed a big shift in my soreness and chronic pain.Go to boncharge.com/WELLFED and use coupon code WELLFED to save 20%

Here are the notes for episode #442 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle, and Michelle Shapiro, RD discuss weight loss and diet changes without diet culture.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[5:32] Interview with Michelle ShapiroLinkshttps://michelleshapirord.com/Quite the Diet podcast: https://podcasts.apple.com/us/podcast/quiet-the-diet/id1663088026Instagram: https://www.instagram.com/michelleshapirord/Dr's ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.OrganifiSupport your body, energy, immunity, and stress with Organifi.Organifi takes pride in offering the best tasting superfood products on the market at a price that works out to less than $3 a day.You can experience Organifi's high-quality superfoods without breaking the bank.Go to www.organifi.com/wellfed and use code wellfed for 20% off your order.Bon ChargeBON CHARGE is a holistic wellness brand with a HUGE range of evidence-based products to optimize your life in every way, including their NEW sauna blankets.Far infrared light works by heating the body up directly, which speeds up your metabolism and sweat rate. It also relaxes muscles and reduces muscle tension, and I've already noticed a big shift in my soreness and chronic pain.Go to boncharge.com/WELLFED and use coupon code WELLFED to save 20%

Here are the notes for episode #441 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle and Stef discuss anxiety about aging, body acne, and food fears.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[15:42] Anxiety About Aging[31:22] Body Acne[38:34] Food FearsDr's ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.KionIf you want to naturally boost energy, build lean muscle, and enhance athletic performance, Get Kion Aminos!  Kion is backed by over 20 years of clinical research, has the highest quality ingredients, no fillers, or junk, and undergoes rigorous quality testing.  They make essential amino acids available in capsules or powders and the powders taste great.You can save 20% on monthly deliveries and 10% on one-time purchases at http://getkion.com/wellfed.LMNTThis podcast is sponsored by LMNT! LMNT makes grab-and-go electrolyte replacement supplementation. You just take an LMNT recharge packet, mix it up with water, and sip! There's absolutely no sugar, gluten, fillers, or artificial ingredients, and it's paleo-friendly.LMNT's co-founder is actually Robb Wolf, who we interviewed on episode #311, so you know the ingredients are solid and it's been well researched and developed.To grab a FREE sample pack of LMNT, go to drinkLMNT.com/wellfed, all you'll have to do is pay for shipping. It's so worth it, and you'll get to test it out extensively! That's drinkLMNT.com/wellfed. Click “get yours” and then grab yourself some packets to have on hand!

Here are the notes for episode #440 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle, and Courtney Babilya discuss myth busting, customization, and fitness adaptations.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[5:21] Interview with Courtney BabilyaLinkswww.courtneykeepingbalance.comhttps://www.instagram.com/courtneykeepingbalanceKeeping Balance App: https://kbm.passion.io/https://www.cnn.com/2022/12/23/health/exercise-fitness-menstrual-cycle-syncing-wellness-partner/index.htmlDr's ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.OrganifiSupport your body, energy, immunity, and stress with Organifi.Organifi takes pride in offering the best tasting superfood products on the market at a price that works out to less than $3 a day.You can experience Organifi's high-quality superfoods without breaking the bank.Go to www.organifi.com/wellfed and use code wellfed for 20% off your order.Bon ChargeBON CHARGE is a holistic wellness brand with a HUGE range of evidence-based products to optimize your life in every way, including their NEW sauna blankets.Far infrared light works by heating the body up directly, which speeds up your metabolism and sweat rate. It also relaxes muscles and reduces muscle tension, and I've already noticed a big shift in my soreness and chronic pain.Go to boncharge.com/WELLFED and use coupon code WELLFED to save 20%

Here are the notes for episode #439 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle and Stef discuss skipping breakfast and your hormones, workout motivation, and dry skin after 35.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[8:41] Skipping Breakfast and Hormones[30:02] Workout Motivation[43:41] Dry Skin After 35LinksSkipping Breakfast#403: Women Are Not Small Men With Dr. Stacy Sims (Renewed)#431: Protein, Essential Amino Acids, And Maintaining And Building Muscle With Angelo KeelyFirst Aid Beauty KP Smoothing Body LotionBotanic Tree KP LotionBeautycounter Sugar Buff Body PolishDigestive EnzymesKionIf you want to naturally boost energy, build lean muscle, and enhance athletic performance, Get Kion Aminos!  Kion is backed by over 20 years of clinical research, has the highest quality ingredients, no fillers, or junk, and undergoes rigorous quality testing.  They make essential amino acids available in capsules or powders and the powders taste great.You can save 20% on monthly deliveries and 10% on one-time purchases at http://getkion.com/wellfed.LMNTThis podcast is sponsored by LMNT! LMNT makes grab and go electrolyte replacement supplementation. You just take an LMNT recharge packet, mix it up with water, and sip! There's absolutely no sugar, gluten, fillers, artificial ingredients, and it's paleo friendly.To grab a FREE sample pack of LMNT, go to drinkLMNT.com/wellfed, all you'll have to do is pay for shipping. It's so worth it, and you'll get to test it out extensively! That's drinkLMNT.com/wellfed. Click “get yours” and then grab yourself some packets to have on hand!Dr.'s ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.

Here are the notes for episode #438 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle, and Liz Wolfe discuss peptide therapy, botox, supplements, and protein intake.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[6:02] Interview with Liz WolfeLinksThe40ish.comhttps://www.instagram.com/realfoodliz/Bon ChargeBON CHARGE is a holistic wellness brand with a HUGE range of evidence-based products to optimize your life in every way, including their NEW sauna blankets.Far infrared light works by heating the body up directly, which speeds up your metabolism and sweat rate. It also relaxes muscles and reduces muscle tension, and I've already noticed a big shift in my soreness and chronic pain.Go to boncharge.com/WELLFED and use coupon code WELLFED to save 20%Dr's ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.OrganifiSupport your body, energy, immunity, and stress with Organifi.Organifi takes pride in offering the best tasting superfood products on the market at a price that works out to less than $3 a day.You can experience Organifi's high-quality superfoods without breaking the bank.Go to www.organifi.com/wellfed and use code wellfed for 20% off your order.

Here are the notes for episode #437 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle and Stef discuss waking up at night, eating more calories, and lowering blood pressure.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[8:52] Waking at Night[22:44] Eating More Calories[31:34] Lowering Blood PressureLinkswww.wellminerals.uswww.coconutsandkettlebells.com/mineralshttp://www.coconutsandkettlebells.com/mineralswww.coconutsandkettlebells.com/turmeric-hot-chocolate/www.coconutsandkettlebells.com/recipes/www.coconutsandkettlebells.com/easy-stovetop-chili/http://www.coconutsandkettlebells.com/easy-stovetop-chili/www.coconutsandkettlebells.com/garlic-butter-steak-bites-and-potatoes/http://www.coconutsandkettlebells.com/garlic-butter-steak-bites-and-potatoes/Dr.'s ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.KionIf you want to naturally boost energy, build lean muscle, and enhance athletic performance, Get Kion Aminos!  Kion is backed by over 20 years of clinical research, has the highest quality ingredients, no fillers, or junk, and undergoes rigorous quality testing.  They make essential amino acids available in capsules or powders and the powders taste great.You can save 20% on monthly deliveries and 10% on one-time purchases at http://getkion.com/wellfed.LMNTThis podcast is sponsored by LMNT! LMNT makes grab and go electrolyte replacement supplementation. You just take an LMNT recharge packet, mix it up with water, and sip! There's absolutely no sugar, gluten, fillers, artificial ingredients, and it's paleo friendly.To grab a FREE sample pack of LMNT, go to drinkLMNT.com/wellfed, all you'll have to do is pay for shipping. It's so worth it, and you'll get to test it out extensively! That's drinkLMNT.com/wellfed. Click “get yours” and then grab yourself some packets to have on hand!

Here are the notes for episode #436 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle, and Shawn Stevenson discuss calorie craziness, brain nutrients, and eating for better sleep.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[4:16] Interview with Shawn StevensonLinks#254: Ending Sleep Struggles with Shawn Stevenson: https://coconutsandkettlebells.com/ending-sleep-struggles-with-shawn-stevenson/Eatsmarterbook.comThemodelhealthshow.comSleep Smarter: https://amzn.to/3trCLlpEat Smarter: https://amzn.to/3cHLXwcBlissyBlissy sells 100% mulberry silk pillowcases that are naturally hypoallergenic, cooling, and unlike other silk pillowcases, Blissy's are machine washable and durable.Blissy has a ton of different prints and colors and they make great gifts because there's an option for literally anyone.Try now risk-free for 60 nights, at Blissy.com/WELLFED and get an additional 30% off with our special code WELLFED.OrganifiSupport your body, energy, immunity, and stress with Organifi.Organifi takes pride in offering the best tasting superfood products on the market at a price that works out to less than $3 a day.You can experience Organifi's high-quality superfoods without breaking the bank.Go to www.organifi.com/wellfed and use code wellfed for 20% off your order.Dr's ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.

Here are the notes for episode #435 of Well-Fed Women. Be sure to check back every Tuesday for a new episode, and head over to Apple Podcasts or Stitcher to subscribe!In this episode, Noelle, and Robb Wolf discuss dialing in hydration, salt intake, and electrolyte supplementation.Got a question you'd like us to answer? Email us at wellfedwomen@gmail.com.5% of the funds we receive from our sponsors is donated directly to our partner charity, Thistle Farms, a place where women survivors of abuse, addiction, trafficking and prostitution receive help and support through residential programs, therapy, education, and employment opportunities. Because we get paid per download, you are actively supporting Thistle Farms by downloading our podcast each week.Timestamps[] Interview with Robb WolfLinksDrinklmnt.com/wellfedRobbwolf.comJoin.thehealthyrebellion.comPodcast: The Healthy Rebellion RadioThe Paleo Solution: https://amzn.to/35Evl3RWired to Eat: https://amzn.to/3i8TgNUSacred Cow: https://amzn.to/38GZqSA#120: Testing Individual Carbohydrate Tolerance, Personalized Nutrition, and Impacts of Sleep Deprivation with Robb Wolf: https://coconutsandkettlebells.com/testing-individual-carbohydrate-tolerance-personalized-nutrition-impacts-sleep-deprivation-robb-wolf/KionAmino acids aren't just for people who do strength training. No matter what you do to stay fit, amino acids are essential!Kion is backed by over 20 years of clinical research, has the highest quality ingredients, no fillers, or junk, and undergoes rigorous quality testing.  They make essential amino acids available in capsules or powders and the powders taste great.If you want to naturally boost energy, build lean muscle, and enhance athletic performance, Get Kion Aminos!  You can save 20% on monthly delivers and 10% on one-time purchases at http://getkion.com/wellfed.Dr's ChoiceDr.'s Choice is formulated with 30 billion live beneficial bacteria per capsule and provides a mixture of 10 Lactobacilli and Bifidobacteria strains, shown through research to be the most beneficial when taken together. It also contains FOS, which is a powerful prebiotic that feeds the probiotic strains.If you struggle with chronic digestive issues, leaky gut, feel like you get sick all the time, or want to optimize your body's ability to break down food, including protein, I highly recommend Dr's Choice Probiotic.  Go to http://mdlogichealth.com/drschoice, and use coupon code WELLFED for 10% off.

Why is yogurt so important? Our body has a brain barrier to protect the brain from harmful organisms and bacteria. The brain barrier needs lactobacilli or L. Plantarum 299V protects our brain. In regular yogurt are a few lactobacilli, but not enough. How to produce the healthiest yogurt with the best lactobacilli?Lactobacilli: “Ideal Bowel Support 299V” (L. Plantarum 299V), (You get it from iherb.com). Or you get Lactobacilli powder a lot cheaper from India through eBay. Produce healthy yogurt with organic soy or GMO-free soy (no white sugar), coconut milk, or almond milk.I prefer coconut milk. Heat milk to 30-35 C. Take a capsule of Ideal Bowel Support 299v, open the capsule, and put the contents in 1l milk. If you use sugar-free soy milk inside, you need to add some honey; shake it well.Keep the milk in a thermos bottle warm for 10 to 12 hours. Fill the yogurt in a container and place it in the fridge.It can be refrigerated for 3-4 days. Next time, you can use this yogurt as a starter to make the next yogurt in the same way. You put a little (0.1l) yogurt in 1l hot milk (30-35C), fill it up in a thermos bottle, shake it well, and wait 6-8hours... Soy is highly beneficial to the body. If you have an allergy to soy or soy products or a thyroid disorder while eating soy, you cannot use soy.  My Video: How to make healthy vegan yogurt? https://youtu.be/xKmVMTI74BMMy Audio: https://divinesuccess.net/wp-content/uploads/2021/Podcast2/How-to-make-healthy-vegan-yogurt.mp3

A new research paper was published in Aging (listed as “Aging (Albany NY)” by MEDLINE/PubMed and “Aging-US” by Web of Science) Volume 14, Issue 17, entitled, “Probiotics treatment for Parkinson disease: a systematic review and meta-analysis of clinical trials.” People with Parkinson's disease (PwP) exhibit gut dysbiosis and considerable gastrointestinal (GI) symptoms. Probiotics, beneficial strains of microorganisms, and supplements optimize the intestinal environment and alleviate GI symptoms among elderly people. In a new study, researchers Chien-Tai Hong, Jia-Hung Chen and Tsai-Wei Huang from Taipei Medical University conducted a systematic review and meta-analysis of clinical trials to investigate the effects of probiotics on people with Parkinson's disease. PubMed, Embase and Cochrane Library databases were used. Six randomized controlled trials (RCTs) and two open-label studies were included. Most of the probiotic regimens were based on Lactobacillus and Bifidobacterium. Six studies investigated the benefit of probiotics for GI symptoms, especially for PwP with functional constipation, and two RCTs assessed probiotics' effect on systematic metabolism and inflammation. Major outcomes were the effects of probiotics on GI symptoms, including bowel movement and stool characteristics. “In the meta-analysis, probiotic treatment significantly increased the frequency of bowel movements among PwP (mean difference [MD]: 1.06 /week, 95% confidence interval [CI]: 0.61 to 1.51, p < 0.001, I2 = 40%). Additionally, probiotic treatment significantly normalized stool consistency (standard MD: 0.61, 95% CI = 0.31 to 0.91, p < 0.001, I2 = 0%).” Although the probiotic compositions varied, the researchers found that probiotic treatment significantly attenuated constipation for people with Parkinson's disease and exhibited possible systematic effects on inflammation and metabolism. Given the tolerability of probiotics, the present meta-analysis may provide more consolidated evidence of the benefit of probiotics on constipation in people with Parkinson's disease and a possible new therapeutic approach for disease modification. “This review and meta-analysis determined that probiotic treatments, mainly Lactobacilli and Bifidobacterium–based regimens, effectively alleviated constipation. Adverse effects are generally tolerable. However, considering the gut microbiota is highly associated with a person's environment and diet, studies from other continents are required to establish the benefit of probiotics on constipation. Moreover, probiotic treatment is likely to affect the systemic inflammation and metabolism of PwP, but further studies are warranted to investigate the possibility of the disease modification effect on PD.” DOI: https://doi.org/10.18632/aging.204266 Corresponding Author: Tsai-Wei Huang – Email: tsaiwei@tmu.edu.tw About Aging-US: Launched in 2009, Aging (Aging-US) publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at www.Aging-US.com​​ and connect with us: SoundCloud – https://soundcloud.com/Aging-Us Facebook – https://www.facebook.com/AgingUS/ Twitter – https://twitter.com/AgingJrnl Instagram – https://www.instagram.com/agingjrnl/ YouTube – https://www.youtube.com/agingus​ LinkedIn – https://www.linkedin.com/company/aging/ Reddit – https://www.reddit.com/user/AgingUS Pinterest – https://www.pinterest.com/AgingUS/ For media inquiries, please contact media@impactjournals.com

What is vaginal hygiene, and how much is too much? Should you wax or shave? What are best practices for keeping it clean and healthy down there? What are common misconceptions women have about vaginal smell? Join us for this episode of Wellness Wednesday as we discuss caring for the "vaginal ecosystem" with our nurse practitioner, Christi!   Resources from our provider: Daily Vaginal Microbiota Fluctuations Associated with Natural Hormonal Cycle, Contraceptives, Diet, and Exercise (nih.gov) The Vaginal Microenvironment: The Physiologic Role of Lactobacilli (nih.gov)   Disclaimer: The information shared in this podcast is the opinion of the speaker, or speakers. Medical information is not intended as individual medical consultation, but for general education only. Always consult your own health professional for personalized advice regarding medical decisions.

Are you totally confused by probiotics or not sure which one to choose? Want to ensure you are getting the best bang for your buck and that your probiotic is actually doing something? Curious about how to pulse your probiotics based on symptoms and season? Tune in to hear Ali and Becki go down the rabbit hole on strain-specific research and discuss what to look for in a probiotic, best formulas for desired clinical outcomes, and how to tell if a probiotic is good quality.    In this episode, Ali and Becki go into detail on some of the most widely researched probiotic strains, from lactobacillus to bifidobacterium to saccharomyces boulardii and beyond. Learn about promising clinical outcomes from reduction of IBS and IBD pain, regulation of bowels post antibiotic, prevention of candida overgrowth, and yeast infection and UTI treatment. Plus we discuss thoughts on probiotics formulated with prebiotics as well as some of the new spore-based probiotics and share our current favorite cultured foods to get a daily dose of probiotics!   Also in this episode: 12 Week Virtual Ketosis Program - Only $99 through 9/1!  Episode 230: Dysbiosis through Disconnection Episode 198: So You're On an Antibiotic Episode 174: The Dysbiosis Disease Connection and Ali's Cleanse Episode 60: Dysbiosis and the Microbiome Episode 68: Supporting Your Immune System Naturally (Deep dive on ear infections & antibiotic use in kids) Episode 87: The Gut Brain Axis Episode 131: Candida and SIBO Deep Dive What is the Microbiome? The Role of Probiotics Probiotics and Immune Health Belkaid Y, Hand TW. 2014. Role of the microbiota in immunity and inflammation. Cell157: 121–141. https://doi.org/10.1016/j.cell.2014.03.011  Collins, N., & Belkaid, Y. (2018). Do the Microbiota Influence Vaccines and Protective Immunity to Pathogens? Engaging Our Endogenous Adjuvants. Cold Spring Harbor perspectives in biology, 10(2), a028860. https://doi.org/10.1101/cshperspect.a028860  Kim, C.H. (2018), Immune regulation by microbiome metabolites. Immunology, 154: 220-229. doi:10.1111/imm.12930  Pickard, J. M., Zeng, M. Y., Caruso, R., & Núñez, G. (2017). Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease. Immunological reviews, 279(1), 70–89. https://doi.org/10.1111/imr.12567  What to Look for When Choosing a ProbioticID Guarantee Why We Don't Include Prebiotics in Our ProbioticsPhytofiber Strain Specific ResearchLactobacillus Acidophilus NCFMD'Souza, B., et al. (2015), ‘Randomized controlled trial of probiotics after colonoscopy'. ANZ Journal of Surgery, doi: 10.1111/ans.13225. Engelbrektson, A.L .et al., (2009). ‘Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy'. Journal of Medical Microbiology, 58:663-670. Engelbrektson, A.L. et al., (2006). ‘Analysis of treatment effects on the microbial ecology of the gastrointestinal tract'. FEMS Microbiol. Ecol. 57:239-250. Faber S.E., (2003), ‘Comparison of probiotics with antibiotics to probiotics alone in treatment of diarrhea predominant IBS (D-IBS), alternating (A-IBS) and constipation (C-IBS) patients', Gastroenterology, 124(4):A687-A688. Faber, S.M., (2000). ‘Treatment of abnormal gut flora improves symptoms in patients with irritable bowel syndrome'. American Journal of Gastroenterology, 95(9):2533. Forssten, S., et al., (2014). ‘Influence of a probiotic mixture on antibiotic induced microbiota disturbances'. World Journal of Gastroenterology, 20(33):11878-85. Leyer, G.J., et al., (2009). ‘Probiotic Effects on Cold and Influenza-Like Symptom Incidence and Duration in Children'. Pediatrics; 124 (2): 172-179. Restore Baseline Probiotic Targeted Strength Probiotic - use code TARGETPRO18 for 18% off  KidsBiotic How to Take Probiotics With Antibiotics Bifidobacterium lactis Bi-07Gobel et al., (2010). ‘Probiotics to young children with atopic dermatitis: A randomized placebo-controlled trial'. International Journal of Probiotics and Prebiotics, 5(2):53-59. Lammers, K.M., (2003). ‘Immunomodulatory effects of probiotic bacteria DNA: IL-1 and IL-10 response in human peripheral blood mononuclear cells'. FEMS Immunology and Medical Microbiology 38: 165-172. Leyer G.J. et al., (2009). ‘Probiotic effects on cold and influenza-like symptom incidences and duration in children'. Pediatrics, 124:72-179. Maneerat S. et al., (2013). ‘Consumption of Bifidobacterium lactis Bi-07 by healthy elderly adults enhances phagocytic activity of monocytes and granulocytes' J Nutr Sci.., 2(2):e44. Masco L. et al., (2004). ‘Polyphasic taxonomic analysis of Bifidobacterium animalis and Bifidobacterium lactis reveals relatedness at the subspecies level: reclassification of Bifidobacterium animalis subsp. Animalis subsp. nov. and Bifidobacterium lactis as Bifidobacterium animalis subsp. Lactis subsp. Nov'. Int. J. System. Evol. Microbiol., 54(4): 1137-1143. Lactobacillus PlantarumRebuild Spectrum Probiotic Post Surgical Protocol Saccharomyces BoulardiiAbbas Z. et al., (2014), ‘Cytokine and clinical response to Saccharomyces boulardii therapy in diarrhea-dominant irritable bowel syndrome: a randomized trial', Eur J Gastroenterol Hepatol, 26(6):630-9. Akil I. et al., (2006), ‘Influence of oral intake of Saccharomyces boulardii on Escherichia coli in enteric flora', Pediatr Nephrol, 21(6):807-10. Algin C., et al. (2005) ‘Effectiveness of Bombesin and Saccharomyces boulardii against the translocation of Candida albicans in the digestive tract in immunosuppressed rats'. Surgery Today, 35: 869. Bafutto M. et al., (2013), ‘Treatment of diarrhea-predominant irritable bowel syndrome with mesalazine and/or Saccharomyces boulardii',Arq Gastroenterol, 50(4):304-9. Berg R. et al., (1993), ‘Inhibition of Candida albicans translocation from the gastrointestinal tract of mice by oral administration of Saccharomcyes boulardii'. J. Infect. Dis. 168(5):1314-8. Billoo A.G. et al., (2006), ‘Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhoea', World J Gastroenterol, 12(28):4557-60. Bin, Z., et al. (2015). The Efficacy of Saccharomyces boulardii CNCM I-745 in Addition to Standard Helicobacter pylori Eradication Treatment in Children. Pediatric Gastroenterology, Hepatology & Nutrition, 18(1), 17–22. Blehaut, H. et al., (1989) ‘Disposition kinetics of Saccharomyces boulardii in man and rat'. Biopharm Drug Dispos, 10: 353–364. Bruggencate T., (2015), ‘The effect of a multi-strain probiotic on the resistance toward Escherichia coli challenge in a randomized, placebo-controlled, double-blind intervention study'. European Journal of Clinical Nutrition, 69:385-391. Burande M.A., (2013), ‘Comparison of efficacy of Saccharomyces boulardii strain in the treatment of acute diarrhea in children: A prospective, single-blind, randomized controlled clinical trial', J Pharmacol Pharmacother, 4(3):205-8. Buts J. et al., (1993), ‘Saccharomyces boulardii for Clostridium difficile-Associated Enteropathies in Infants'. Journal of Pediatric Gastroenterology and Nutrition, 16:419-425. Lactobacillus rhamnosus & Lactobacillus reuteriAnukam et al., (2006), ‘Clinical study comparing probiotic Lactobacillus GR-1® and RC-14® with met*******ole vaginal gel to treat symptomatic bacterial vaginosis'. Microbes Infect.8(12-13):2772-6. Anukam K.C. et al., (2006), ‘Augmentation of antimicrobial met*******ole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, placebo controlled trial'. Microbes Infect. 8(6): 1450-4. Anukam et al., (2009), ‘Oral use of probiotics as an adjunctive therapy to fluconazole in the treatment of yeast vaginitis: A study of Nigerian women in an outdoor clinic'. Microb. Ecol. Health Dis., 21(2):72-77. Beerepoot et al., (2012), ‘Lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women'. Arch. Intern. Med., 172(9):704-12. Women's Flora Probiotic BacteriophagesGI Clean Up Probiotic Challenge Choosing the Right Probiotic Chart What About Soil Based Probiotics Favorite Probiotic Foods   Sponsors for this Episode:  This episode is sponsored by the Naturally Nourished supplement line: these pure, potent and effective formulas have been hand selected to deliver profound health benefits. We price our formulas 2-5% below market industry standard and competitors and guarantee that our products will always be third party assessed to ensure they are free of mold, toxins, contaminants, and contain the stated active ingredients in dosages noted.  Use code ALI15 for 15% off your first Naturally Nourished Supplement Order!    This episode is also sponsored by Santa Cruz Medicinals, makers of potent and affordable CBD with effective dosing. For more information check out www.scmedicinals.com and use code ALIMILLERRD for 15% off your order. 

Welcome to episode 460 of The Whole View! This week, Sarah and Stacy look at the science behind antibiotics' impact on the gut microbiome and what we can do to break the Stress-Flare-Antibiotic Cycle as much as possible. Stacy gives insight into actions you can take outside the body, while Sarah dives deep into foods and lifestyle habits that can help from within.  If you enjoy the show, please review it on iTunes! The Whole View, Episode 460: How to Break the Stress-Flare-Antibiotic Cycle Welcome back to episode 460! (0:28) This week's episode was inspired by a lister question. As always, Stacy and Sarah pick questions that really resonate with the: First off, my mother and I love your show and have been listening to the show for years. I love how you can tackle complicated topics and boil them down to easy to understand and enjoyable shows. Stacy, your journey with your son through ADHD was such a help for me when my oldest son was diagnosed. It gave me a place to go when I wasn't sure where to go next. Now to the reason I'm writing to you.  I have been battling rosacea flares ever since 2010 when I had my first son. Pregnancy seemed to set everything off and I now deal with flares off and on. I know stress is a trigger. My dermatologist's answer is always to put me on antibiotics for months at a time and it's killing my gut health.  I had finally gotten my gut health to a pretty good place and hadn't needed to be treated for quite some time and then Covid hit, my mother-in-law moved in, and I started remote schooling 3 extra kids in my home along with my own children. No stress here! My question is, how do I maintain my gut health when I have Rosacea and have to use antibiotics to control the flare? Thank you for all the hard work you ladies put into your shows!  -Sara Sometimes, the flare itself can be additional stress and can snowball the problem.  Lifestyle changes aren't going to solve the issue independently, but adding different choices in where you can certainly help manage symptoms.  First, Medication Isn't Failure! In some situations, antibiotics are absolutely needed. (7:09) It's definitely smart to avoid antibiotics when they aren't really necessary (like viral flu and colds). But when it comes to certain illnesses and infections (the ones used to wipe out huge chunks of the human population!), antibiotics can prevent serious complications and even save our lives.  There's no reason we should ever feel guilty or like we've "failed" just because we need to take antibiotics.  While following a healthy diet and lifestyle typically supports much stronger and well-regulated immune systems, it does not (sadly) make us invisible.   The necessity for antibiotics doesn't mean that you didn't "Paleo/AIP/Nutrivore hard enough," so don't be hard on yourself.   While it's always a good idea to reflect on ways to improve the quality and consistency of our diet and lifestyle choices, what's most important while recovering from illness is making science-based, informed choices that give us the best chance of getting healthy efficiently! Preventative Skincare  Stacy refers listeners back to the episode on Dry Winter Skin because of the information on the moisture barrier in that show. (12:15) She also recommends checking out Science of the Skin Barrier. Beauty counter has a great Safe SPF Stacy loves! She cautions listeners to be wary of the ingredients in their products when shopping for sunscreen.  Studies have shown that many modern SPF on the market (chemical and mineral) have large amounts of Benzine contaminants, a known carcinogen. There are prescription topical medications to help with issues such as Rosacea. That is another option to talk to your doctor about.  Another known thing to irritate Rosacea is using hot water and dairy consumption.  Sarah adds that red light therapy is another interesting avenue to look into to add to your preventative care. Self Care and Stress vs. Sleep Stress is a huge trigger for Sarah, and despite being proactive at preventing stress, it's not 100%. (18:01) Sarah and Stacy have talked about the stress, work-life balance, and stress-sleep cycle on quite a few recent shows: 458: Collective Trauma and Re-Entry Anxiety 447: Basic Needs Don't Count as Self-Care 446: Nutrient Deficiencies Caused by Stress  409: Let's Talk About Magnesium 397: Practical Tips for the Sleep Stress Cycle 351: Stress on Health Sarah explains that her biggest obstacle is her perfectionist tendencies. It's critical to put self-care on our busy to-do lists! Self-care doesn't have to mean a mani-pedi. It can be as easy as giving yourself time to do something you enjoy. Resilience activities like going for a walk, meditating, or cuddling with a pet are great ways to give yourself some time away. Stacy reminds listeners that they are allowed to let go and say no.  Focusing on sleep when we can't control stress is another great way to help your body as much as possible.  Antibiotics vs. Gut Health The word literally means "against life" from its Greek roots. (27:10) Antibiotics stop or slow down the growth of microscopic organisms (bacteria, fungi, and some parasites), in turn, treating potentially dangerous infections.  Antibiotics can also destroy beneficial bacteria and yeast that mediate an incredible array of processes in our body. This can include gut barrier integrity, tuning the immune system, and increasing the bioavailability of nutrients from our food!  So, whenever we embark on antibiotic therapy, the goal should be to protect, preserve, and restore these beneficial organisms as soon as possible. Antibiotics, by design, are very destructive to the gut microbiome, which is why so many gastrointestinal side effects are reported. Taking Probiotics While on Antibiotics It's a myth that we should wait until we've finished a course of antibiotics before trying to rebuild our gut flora with probiotics. (29:52) In reality, taking probiotics during antibiotic therapy is one of the most helpful things we can do to maintain gut health! Even if the probiotics we ingest during antibiotic therapy don't take up permanent residence yet, they can still help keep pathogens at bay and prevent crazy microflora imbalances. Several studies have examined the effects of probiotics on antibiotic-induced side effects, and the results have been impressive!  Probiotics can go a long way to reduce unpleasant symptoms, especially gastrointestinal distress like diarrhea. This can occur when antibiotics wipe out the competitors for pathogenic bacteria and allow diarrhea-inducing strains to flourish.  One meta-analysis looked at 63 trials on probiotics to prevent antibiotic-associated diarrhea and found a major reduction in diarrhea when people took Lactobacillus-based probiotics. Other meta-analyses found that Saccharomyces boulardii and Lactobacillus rhamnos, in particular, were very helpful for reducing antibiotic-associated diarrhea.  And, additional studies have found various probiotic strains (especially Lactobacillus) can help reduce nausea, taste disturbance, headaches, hypersensitivity, and other symptoms when taken during a round of antibiotics! One study tested the effects of starting probiotics (Lactobacillus acidophilus and Bifidobacterium bifidum) after antibiotic therapy versus during antibiotic therapy.  The group that started taking probiotics while still on antibiotics had more stable microflora levels and less gut dysbiosis throughout the experiment! Taking Action Against the Stress-Flare-Antibiotic Cycle Sarah recommends loading up on fermented foods teeming with natural probiotics. These include raw, unpasteurized sauerkraut, kimchi, fermented carrots, fermented beets, pickles, fermented fruits (chutneys, jams, pickled jackfruit, green papaya), kombucha, beet kvass, coconut milk kefir, coconut milk yogurt, and raw condiments.  For people who aren't sensitive to dairy or soy, unpasteurized yogurt and kefir, natto, miso, tempeh, and tamari sauce are also great options.  For the best results, eat these foods 2 to 4 hours after an antibiotic dose. Sarah also recommends taking probiotic supplements, especially if you're yeast or histamine sensitive or otherwise don't do well with fermented foods.  For preventing antibiotic-associated diarrhea and other side effects, an intake of at least 5 billion CFU/day for children or 10 billion CFU/day per adult is recommended.  Several existing trials show that Lactobacilli, Bifidobacteria, and Saccharomyces boulardii are the most effective types for reducing antibiotic side effects.  All probiotics should be consumed with food, and bacterial strains should be taken at least 2 to 4 hours after each antibiotic dose so that they don't get inhibited by the antibiotic itself.  Saccharomyces boulardii is actually a form of probiotic yeast, making it particularly useful while taking bacteria-killing antibiotics.  Don't forget to consume plenty of gut barrier nutrients! What to Do After Taking Antibiotics Stacy adds that reintroducing known trigger foods should only happen when your flare is over to prevent the stress-flare-antibotic cycle. (39:02) Once we've completed antibiotic therapy, it's time to seriously buckle down and get our gut microbiome back in shape. Chances are, the antibiotics caused a major loss in microbial diversity, wiped out many beneficial species, and may have allowed pathogenic strains to flourish.  So, the goal is to rebalance the microbiome and restore as much (good) diversity as possible! There's a really immense amount of information in The Gut Health Guidebook, but it all boils down to 20 keys to gut health.  A healthy gut microbiome eats a nutrient-dense and varied diet that is moderate-fat and moderate-carb to best support a healthy gut microbiome. That includes plenty of veggies, fruit, mushrooms, and seafood, rounded out with nuts, seeds, grass-fed meats, fermented foods, and phytochemical-rich foods like herbs, tea, coffee, cacao extra virgin olive oil.  437: Intro To Nutrivore 424: 30 Fruits and Vegetables a Week?! 373: How Many Vegetables (Part 4) Powdered Veggies 304: What's Better: Raw or Cooked Vegetables? 335: How Many Vegetables Part 3: Souping vs Smoothies 281: How Many Vegetables?! 413: The Gut Health Benefits of Nuts 415: Fish oil, Healthy or not? 414: Best Cooking Fats for Gut Health Lifestyle Choices that Help Fight the Stress-Flare-Antibiotic Cycle Be sure you're hydrating without alkaline water. Lifestyle factors are also essential, like getting enough sleep on a consistent schedule, entrenching a solid circadian rhythm, eating distinct meals instead of grazing, fasting overnight (12-14 hours, not IFing), living an active lifestyle managing stress. It's also super important to optimize vitamin D levels. For more info, see Episode 354: Everything Vitamin D. A handful of traditionally excluded foods on the Paleo diet is a boon to our gut microbiomes. This includes A2 dairy like goat, sheep, or camel), most legumes (not soy or peanuts), pseudo-grains, corn, rice, and gluten-free oats.  However, none of these latter foods are fundamental for a healthy gut microbiome in the same way that mushrooms, seafood, and individual families of vegetables and fruit are. Continue eating plenty of raw, unpasteurized, fermented foods throughout the day. These typically contain a huge spectrum of probiotic species and offer greater microbial diversity than most probiotic supplements.  Lacto-fermented fruits, vegetables, and beverages tend to be high in Lactobacillus and Bifidobacteria, while kefir and kombucha are great sources of Saccharomyces boulardii.  Eat from as many fermented foods as possible to get a variety of awesome microbes, both bacterial and yeast! For more information, see Episode 329: The Link Between Carb Intolerance & Gut Health and Episode 457: The Problem with a Low-FODMAP Diet. Studies have shown that SBOs like Just Thrive helps Lactobacillus grow and can help restore the gut microbiome after antibiotics.  Just Thrive is not sponsoring this episode, but you can still use TWV link for discounts on their products and get 15% off with the code THEWHOLEVIEW at checkout! Stacy and Sarah recommend two probiotics from Smidge: Yeastbiotic and Probiotic. Final Thoughts The most important thing to do when managing the stress-flare-antibiotic cycle is to give your body what it needs to perform optimally. (50:50) This is also why modern diet-culture is such an issue. Our goal is health, and when we focus on it, we see a lot of the claims made by diet culture aren't scientifically supported to optimize health.  The idea of weight loss is often enough to justify choices that make us feel sluggish or sick, and it takes rerouting our mindset toward health to see through it.  There's no one-size-fits-all recipe for feeling good. It's about listening to your body and finding out what makes you feel your best. It's not about how much you weigh.  Stacy reminds listeners interested in Beautycounter safer skincare to use the code CLEANFORALL20 for 20% off their purchase.  Be sure to hop over to Patreon for Stacy and Sarah's unfiltered thoughts for more on this topic. Your subscription helps support this podcast and gets you front-line access to the Whole View. Thanks for listening and we will see you next week!   Want more info on our Real Life? Never miss a post with our Real Everything newsletter (and get our best selling book, Eat Like a Dinosaur, as a welcome gift). Join here Wanna be Healthy Inside & Out? Get educational info and exclusive sales with our non-toxic living newsletter (and get free samples as a thank you for joining our safer skincare community). Join here  

Growing evidence fruit may lower type 2 diabetes risk Research has found eating at least two serves of fruit daily has been linked with 36% lower odds of developing type 2 diabetes Edith Cowan University (Australia), June 2, 2021 Eating at least two serves of fruit daily has been linked with 36 percent lower odds of developing type 2 diabetes, a new Edith Cowan University (ECU) study has found.  The study, published today in the Journal of Clinical Endocrinology and Metabolism, revealed that people who ate at least two serves of fruit per day had higher measures of insulin sensitivity than those who ate less than half a serve.  Type 2 diabetes is a growing public health concern with an estimated 451 million people worldwide living with the condition. A further 374 million people are at increased risk of developing type 2 diabetes. The study's lead author, Dr Nicola Bondonno from ECU's Institute for Nutrition Research, said the findings offer fresh evidence for the health benefits of fruit.  "We found an association between fruit intake and markers of insulin sensitivity, suggesting that people who consumed more fruit had to produce less insulin to lower their blood glucose levels," said Dr Bondonno.  "This is important because high levels of circulating insulin (hyperinsulinemia) can damage blood vessels and are related not only to diabetes, but also to high blood pressure, obesity, and heart disease. "A healthy diet and lifestyle, which includes the consumption of whole fruits, is a great strategy to lower your risk of developing type 2 diabetes." Fresh is best The study examined data from 7,675 Australians participating in the Baker Heart and Diabetes Institute's AusDiab Study and assessed fruit and fruit juice intake and the prevalence of diabetes after five years. Dr Bondonno said they did not observe the same beneficial relationship for fruit juice.  "Higher insulin sensitivity and a lower risk of diabetes was only observed for people who consumed whole fruit, not fruit juice," she said.  "This is likely because juice tends to be much higher in sugar and lower in fibre."  Dr Bondonno said that it's still unclear exactly how fruit contributes to insulin sensitivity, but it is likely to be multifaceted.  "As well as being high in vitamins and minerals, fruits are a great source of phytochemicals which may increase insulin sensitivity, and fibre which helps regulate the release of sugar into the blood and also helps people feel fuller for longer," she said. "Furthermore, most fruits typically have a low glycaemic index, which means the fruit's sugar is digested and absorbed into the body more slowly."  The study builds on Dr Bondonno's research into the health benefits of fruit and vegetables, particularly those that contain a key nutrient known as flavonoids. The research is part of ECU's Institute of Nutrition Research.     Ginkgo biloba leaves have multicomponent and multitarget synergistic effects on treatment of neurodegenerative diseases Jiangsu Kanion Pharmaceutical Co (China), June 1, 2021 According to news reporting out of Jiangsu, People's Republic of China, research stated, “Ginkgo biloba L. leaves (GBLs), as widely used plant extract sources, significantly improve cognitive, learning and memory function in patients with dementia. However, few studies have been conducted on the specific mechanism of Neurodegenerative diseases (NDs).” Our news journalists obtained a quote from the research from Jiangsu Kanion Pharmaceutical Co. Ltd., “In this study, network pharmacology was employed to elucidate potential mechanism of GBLs in the treatment of NDs. Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) was used to obtain the chemical components in accordance with the screening principles of oral availability and drug-like property. Potential targets of GBLs were integrated with disease targets, and intersection targets were exactly the potential action targets of GBLs for treating NDs; these key targets were enriched and analyzed by the protein protein interaction (PPI) analysis and molecular docking verification. Key genes were ultimately used to find the biological pathway and explain the therapeutic mechanism by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. Twenty-seven active components of GBLs may affect biological processes such as oxidative reactions and activate transcription factor activities. These components may also affect 120 metabolic pathways, such as the PI3K/AKT pathway, by regulating 147 targets, including AKT1, ALB, HSP90AA1, PTGS2, MMP9, EGFR and APP. By using the software iGEMDOCK, the main target proteins were found to bind well to the main active components of GBLs.” According to the news editors, the research concluded: “GBLs have the characteristics of multi-component and multi-target synergistic effect on the treatment of NDs, which preliminarily predicted its possible molecular mechanism of action, and provided the basis for the follow-up study.” This research has been peer-reviewed.     Diets that promote inflammation could increase breast cancer risk Analysis of dietary patterns for over 350,000 women suggests eating more anti-inflammatory foods helps lower risk Catalan Institute of Oncology and Biomedical Research Institute (Spain) June 7, 2021  A new study of more than 350,000 women found that women with diets incorporating more foods that increase inflammation in the body had a 12% increase in their risk of breast cancer compared to women who consume more anti-inflammatory diets. The new findings are being presented at NUTRITION 2021 LIVE ONLINE.  The study authors found that moving from a more anti-inflammatory diet toward one that increases inflammation upped breast cancer risk in an almost linear manner. Foods that increase inflammation include red and processed meat; high-fat foods such as butter, margarines and frying fats; and sweets including sugar, honey and foods high in sugar. Fruits, vegetables, legumes, tea and coffee all have potentially anti-inflammatory properties. "Most studies examining diet and breast cancer risk have focused on single nutrients or foods rather than the whole diet," said the study's first author Carlota Castro-Espin, a predoctoral fellow at the Catalan Institute of Oncology and Bellvitge Biomedical Research Institute in Barcelona, Spain. "People consume food not nutrients, thus examining overall dietary patterns, rather than single components of diets can lead to more accurate conclusions when analysing associations with a health outcome such as breast cancer."  The new results are based on data from the European Investigation into Cancer and Nutrition (EPIC) study, a prospective study that recruited more than 500,000 participants across 10 European countries starting in the mid-1990s. The study included more than 13,000 breast cancer diagnoses during approximately 15 years of follow-up.  The typical diet for EPIC participants was measured for a year using food frequency or diet history questionnaires. The researchers used this information to calculate an inflammatory score for each study participant based on their intake of 27 foods.  The researchers examined dietary patterns linked with inflammation because long-term, low grade inflammation has been linked with the development of breast cancer. The large number of women in the study allowed the researchers to take a more nuanced look at the relationship between dietary patterns and breast cancer risk.  Their analysis showed that the increase in breast cancer risk due to pro-inflammatory diets appears to be more pronounced among premenopausal women. They also found that the association did not vary by breast cancer hormone receptor subtypes.  "Our results add more evidence of the role that dietary patterns play in the prevention of breast cancer," said Castro-Espin. "With further confirmation, these findings could help inform dietary recommendations aimed at lowering cancer risk."  As a next step, the researchers plan to evaluate the association of the inflammatory potential of diet and other dietary patterns with breast cancer survival using participants in the EPIC study.      Emerging impact of quercetin in the treatment of prostate cancer Shahid Beheshti University of Medical Sciences (Iran), June 3, 2021   According to news originating from Tehran, Iran, research stated, “Quercetin is a flavonoid agent detected in fruits and vegetables with anti-inflammatory, antioxidant, and anticancer effects. This flavonoid can suppress cell cycle transition and induce apoptosis in neoplastic cells.” Our news reporters obtained a quote from the research from Shahid Beheshti University of Medical Sciences: “Therapeutic effects of quercetin have been assessed in diverse cancers including prostate cancer through the establishment of in vitro and in vivo experiments. Moreover, this agent might prevent the initiation of this type of cancer as it indirectly blocks the activity of promoters of two important genes in the pathogenesis of prostate cancer i.e. androgen receptor (AR) and prostate specific antigen (PSA). Several in vitro investigations have identified the differential influence of quercetin on normal prostate cells versus neoplastic cells, emphasizing its specific cytotoxic effects on cancerous cells. The most appreciated route of quercetin effect on prostate cancer cells is the detachment of Bax from Bcl-xL and the stimulation of caspase families. Besides, quercetin might enhance the effects of other therapeutic options against prostate cancer. For instance, a combination of TNF-related apoptosis-inducing ligand (TRAIL) and quercetin has been recommended as a novel modality for the treatment of prostate cancer.” According to the news editors, the research concluded: “These kinds of strategies might overcome resistance to apoptosis in cancer cells. In the current paper, we summarize the recent data about the preventive and therapeutic influences of quercetin in prostate cancer.”     Breast microbiome modified by diet, fish oil Wake Forest School of Medicine, June 4 2021.    Findings reported on June 3, 2021 in Cancer Research add evidence to the effects of diet on the breast's microbiome, the community of microorganisms that exists in breast tissue.  “We have recently demonstrated that dietary patterns modulate mammary microbiota populations,” wrote David R. Soto-Pantoja and colleagues. “An important and largely open question is whether the microbiome of the gut and mammary gland mediates the dietary effects on breast cancer.” To help answer this question, the researchers fed a high fat or a control diet to mice that are susceptible to developing breast cancer. Animals that received the high fat diet had a greater number of tumors, more rapid tumor growth and larger tumor size than those that received the control diet.  Next, mice that were given high fat diets received fecal transplants from mice that received control diets, and control diet-fed animals received transplants from high fat diet-fed animals. The team found that animals that received the control diet developed as many tumors as mice that received the high fat diet.   In a double-blind trial, breast cancer patients were given fish oil supplements or a placebo for two to four weeks prior to surgical removal of their tumors. The researchers observed a change in the microbiota of tumor and normal breast tissue in participants who received fish oil, including an increase in Lactobacilli (which has been associated with reduce breast cancer tumor growth in animals) in normal tumor-adjacent breast tissue of participants who received fish oil for four weeks.  "Obesity, typically associated with a high-fat diet consumption, is a well-known risk factor in postmenopausal breast cancer," commented coauthor Katherine L. Cook, PhD, of Wake Forest University. "This study provides additional evidence that diet plays a critical role in shaping the gut and breast microbiome."     Self-administered aroma foot massage may reduce symptoms of anxiety   Okayama University (Japan), June 8, 2021  Researchers at Okayama University conduct the first community-based study on the effects of self-administered aromatherapy foot massage on stress and anxiety symptoms. The results suggest aromatherapy massages might provide an inexpensive, simple way of managing anxiety.   The continuing popularity of complementary therapies, such as aromatherapy and massage, has prompted scientists to investigate the effects of such therapies on the body in more detail. Complementary therapies are said to reduce the symptoms associated with stress and anxiety, and therefore may reduce the chances of severe illness, such as hypertension and heart disease. The precise effects on the body following such therapies is unclear, however.   Previous studies have focused on the effects of massage and aromatherapy treatments on blood pressure and mental state in hospitalized patients in Japan, but none have been conducted on individuals living in the community. Now, Eri Eguchi and co-workers at Okayama University, together with researchers across Japan, have conducted the first study into the effect of aromatherapy-based foot massage on blood pressure, anxiety and health-related quality of life in people living in the community.   57 participants took part in the study; 52 women and 5 men. Baseline blood pressure and heart rate values were taken at the start and end of the four-week trial period, as well as at a follow-up session 8 weeks later. Participants also completed questionnaires on anxiety status and health-related quality of life at each stage of the trial. The participants were divided into two groups, and one group were taught to perform a 45-minute aromatherapy-based foot massage on themselves three times a week for four weeks.   The results suggest that aroma foot massage decreased the participants' average blood pressure readings, and state of anxiety, and tended to increased mental health-related quality of life score. However the effect of massages was not significant with changes in other factors such as physical health-related quality of life scores and heart rate.   In their paper published in March 2016 in PLOS One, Eguchi's team are cautiously optimistic about the potential for self-administered massage to reduce anxiety in the population: "[although] it was difficult to differentiate the effects of the aromatherapy from the effects of the massage therapy... [the combination] may be an effective way to increase mental health and improve blood pressure."     Aromatherapy and massage Aromatherapy has long been used to relieve stress and anxiety in populations across the globe. Different aroma essential oils are said to have different properties, and are used to induce relaxation and promote well-being. Trials have indicated that certain essential oils, when inhaled, can reduce blood pressure levels and alleviate depression by stimulating the olfactory system. Massage (in its many forms) also has a long history in therapeutic medicine, and the practice of manipulating key pressure points in the body to induce relaxation has been shown to improve mental and physical health. However, detailed scientific studies of the effects of aromatherapy foot massage – an increasingly popular treatment in Japan – on blood pressure and perceived quality of life are limited.   Significance and further work While the trial carried out by Eguchi and her team is limited in some respects, their results provide an initial starting point from which to extend studies into the benefits of aroma foot massage for the general population. Their findings that massage, or the aromatherapy, or a combination of both, reduce blood pressurereadings (at least in the short term) warrants further investigation. Eguchi and her team acknowledge that their decision to advertise for participants may have encouraged more health-conscious and pro-active people to apply. They also received far more applications from women than men, although their age-range (from 27 to 72) was diverse. Further work is needed to determine the effect of aroma foot massage on specific age and sex categories, for example, before such interventions are encouraged in the wider population.     Proteomics reveals how exercise increases the efficiency of muscle energy production University of Copenhagen (Denmark), May 27, 2021 Mitochondria are the cell's power plants and produce the majority of a cell's energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation. A number of different proteins in mitochondria facilitate these processes, but it's not fully understood how these proteins are arranged inside mitochondria and the factors that can influence their arrangement. Now, scientists at the University of Copenhagen have used state-of-the-art proteomics technology to shine new light on how mitochondrial proteins gather into electron transport chain complexes, and further into so-called supercomplexes. The research, which is published in Cell Reports, also examined how this process is influenced by exercise training.  "This study has allowed for a comprehensive quantification of electron transport chain proteins within supercomplexes and how they respond to exercise training. These data have implications for how exercise improves the efficiency of energy production in muscle," says Associate Professor Atul S. Deshmukh from the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) at the University of Copenhagen.  Traditional methods provide too little detail It is already well established that exercise training stimulates mitochondrial mass and affects the formation of supercomplexes, which allows mitochondria in skeletal muscle to produce energy more efficiently. But questions remain about which complexes cluster into supercomplexes and how. To better understand supercomplex formation, particularly in response to exercise, the team of scientists studied two groups of mice. One group was active, and given an exercise wheel for 25 days, and the second group was sedentary, and was not provided the exercise wheel. After 25 days, they measured the mitochondrial proteins in skeletal muscle from both groups to see how the supercomplexes had changed over time.  When scientists typically analyze how supercomplexes form, they use antibodies to measure one or two proteins per electron transport chain complex. But as there can be up to 44 proteins in a complex, this method is both time consuming and provides limited information about what happens to the remainder of the proteins in each complex.  As a result, there is a lack of detailed knowledge in the field. Proteomics helps supercomplexes give up their secrets To generate much more detailed data, the team applied a proteomic technology called mass spectrometry to measure the mitochondrial proteins. By applying proteomics instead of antibodies, the scientists were able to measure nearly all of the proteins in each complex. This provided unprecedented detail of mitochondrial supercomplexes in skeletal muscle and how exercise training influences their formation. Their approach demonstrated that not all of the proteins in each complex or a supercomplex respond to exercise in the same manner.  "Mitochondrial protein content is known to increase with exercise, thus understanding how these proteins assemble into supercomplexes is crucial to decipher how they work. Our research represents a valuable and precious resource for the scientific community, especially for those studying how the mitochondrial proteins organize to be better at what they do best: produce energy under demand,", explains Postdoc Alba Gonzalez-Franquesa. The interdisciplinary project was a collaboration between the Deshmukh, Treebak and Zierath Groups at CBMR, and the Mann Group at the Novo Nordisk Foundation Center for Protein Research.

The Whole View, Episode 457: The Problem with a Low-FODMAP Diet Welcome back to episode 457! (0:28) Sarah and Stacy last covered FODMAPs in detail in TPV Podcast Episode 238, What's a FODMAP and Why Do Some People Avoid Them? The science on them has definitely evolved, so it's time to revisit what FODMAPs are and why there can be a problem with a low-FODMAP diet! This show is sponsored by Stacy and Sarah's favorite probiotic company, Just Thrive! Formulated by microbiologists, Just Thrive Probiotic includes four science-backed, clinically proven, super-beneficial Bacillus species. It is free of wheat, gluten, Dairy, nuts, soy, salt, sugar, artificial colors or flavors, binders, fillers, allergens, and GMO's. Stacy and Sarah only invite brands they love to be a part of this show and never endorse something they don't use themselves. Just Thrive is offering 15% off with code THEWHOLEVIEW at checkout, or follow this link! Quick Review of FODMAPs The term FODMAP is an acronym for Fermentable Oligosaccharides, Monosaccharides, Disaccharides, and Polyols. (4:10) FODMAPs are sugar alcohols and short-chain carbohydrates rich in fructose molecules.  These molecules are inefficiently absorbed in the small intestine but are highly fermentable by our gut bacteria in the large intestine.   Many dietary carbohydrates that have prebiotic actions are members of the FODMAP group of carbohydrates: Fructo-oligosaccharides (FOS), galactooligosaccharides (GOS), xylooligosaccharides (XOS), polyols, and fructose.  These FODMAPs selectively stimulate the growth of super beneficial specific types of bacteria. They include Bifidobacteria, Lactobacillus, Akkermansia municiphila, Faecalibacterium prausnitzii, Roseburia intestinalis, Eubacterium rectale, and Anaerostipes caccae. When FODMAPs enter the large intestine full of those wonderful beneficial bacteria, they increase the metabolic activity of our gut bacteria. This increases the production of SCFAs and gasses.  Because of the increase in production, we might notice even if we eat a ton of FODMAPs all at once is an increase in flatus frequency. Sarah adds that this is perfectly normal.   FODMAP Intolerance Where it flips into FODMAP intolerance is when it becomes uncomfortable. (10:34) Typical symptoms of FODMAPs include bloating, gas, cramps, diarrhea, constipation, indigestion, and sometimes excessive belching.  This is why a typical diagnosis is Irritable Bowel Syndrome. Some researchers even believe that 100% of IBS is caused by FODMAP intolerance. So, what causes FODMAP intolerance? There's three potentially overlapping, causes Gluten and/or Dairy sensitivity Fructose malabsorption Gut dysbiosis Gluten Sensitivity The biggest source of FODMAPs in the Standard American Diet is wheat.  This is because wheat is consumed in large quantities, not because it is a concentrated source of FODMAPs. Additionally, up to 55% of the population (in North America) has gluten sensitivity genes!  Symptoms of non-celiac gluten sensitivity include IBS bloating, gas, cramps, diarrhea, constipation, indigestion, and belching. PLUS extra-intestinal symptoms, such as brain fog, fatigue, lethargy, skin rash (including eczema), headaches, fibromyalgia-like symptoms (joint and/or muscle pain), carpal tunnel and peripheral neuropathy-like symptoms, depression, anxiety, and anemia 2012 double-blind elimination and challenge study showed 30% of IBS was wheat sensitivity. Stacy and Sarah discussed these genes in detail in TPV Podcast, Episode 293: Do I Have to Be Gluten-Free Forever? Dairy Sensitivity And lactose is a FODMAP! Lactose intolerance is caused a deficiency in the enzyme lactase. Rates of intolerance vary widely based on ethnicity, ranging from 5% among Northern Europeans to over 90% of the population in some Asian and African countries.  In fact, in the US alone, somewhere between 30 and 50 million people are lactose intolerant! Also, epidemiological reports of cow's milk allergy (IgE antibody reactions to cow's milk proteins) range from between 1 and 17.5% in preschoolers, 1 and 13.5% in children ages 5 to 16 years, and 1 to 4% in adults.  The prevalence of cow's milk sensitivities (IgA and IgG antibody reactions to cow's milk proteins) in the general population is unknown. But one study in patients with Irritable Bowel Syndrome showed that a whopping 84% of participants tested positive for IgG antibodies against milk proteins.  Other Food Sensitivities Soy is also a high-FODMAP food. The rate of soy IgG intolerance in IBS is about 23%. IBS is strongly linked to food sensitivity. And up to 65% of people have symptoms resolved if they do IgG testing and eliminate all the positives.  Some people eliminate FODMAPs, and their symptoms go away. So they think it's FODMAP intolerance, but it's really gluten, Dairy, soy, or other sensitivity. So, they're eliminating a ton of healthy fruits and veggies needlessly! Sarah and Stacy will get into why that's important.   Fructose Malabsorption After digestion, monosaccharides are absorbed into the bloodstream by being transported through the cells that line the small intestine, the enterocytes. (20:54) Enterocytes have specialized transporters, or carriers, embedded into the membrane that faces the inside of the gut.   FODMAP intolerance may be due to insufficient carbohydrate carriers, specifically GLUT5, which is the specific carbohydrate carrier for fructose. This can happen, for example, in celiac disease, where you have intestinal villous atrophy. Fructose uptake rate by GLUT5 is also significantly affected by diabetes mellitus, hypertension, obesity, and inflammation. This uptake rate is also influenced by diet! The simultaneous presence of glucose can inhibit uptake, which is why whole fruit might be tolerated where something like agave might not. Additionally, the simultaneous presence of sorbitol can inhibit this. It's important to note that while fructose malabsorption causes symptoms extremely similar to IBS, it's considered a separate diagnosis. However, due to the similarity in symptoms, patients with fructose malabsorption often fit the profile of those with irritable bowel syndrome. Stacy adds that she and Sarah are not medical professionals. If you are struggling with symptoms like those listed, it's best to arm yourself with this knowledge and seek trained professionals to help narrow down your diagnosis.   Gut Dysbiosis The most likely cause of symptoms is actually Gut Dysbiosis.  If there's an imbalanced gut microbiome, such as the right species for cross-feeding (or a high consumption of FODMAPs all at once), this causes a variety of digestive symptoms,  For example, it has been shown that consuming fructans increases the production of butyrate. But the two main types of bacteria that ferment fructans (Bifidobacteria and Lactobacilli) are lactic acid-producing bacteria. Many other bacteria (including Eubacterium, Roseburia, and Faecalibacterium) account for this bump in butyrate production. Acetate serves as an essential co-factor and metabolite for key bacteria like Faecalibacterium prausnitzii, which requires acetate to grow.  The Most Likely Culprit Studies confirmed that gut dysbiosis is the most likely culprit in IBS. This study compared participants with IBS to healthy controls.  Another study detected dysbiosis in 73% of IBS patients vs. 16% of healthy individuals.  This basically captures all the people with IBS symptoms that don't have food sensitivities (with some overlap) And studies confirm more gas production from FODMAP consumption in people with IBS. This study aimed to compare the patterns of breath hydrogen and methane and symptoms produced in response to diets that differed only in FODMAP content. They concluded dietary FODMAPs induce prolonged hydrogen production in the intestine that is greater in IBS. Sarah has taken part in several different breath tests in her lifetime and always finds them interesting.   The problem with a low-FODMAP Diet A huge number of studies show that when people with IBS follow a low-FODMAP diet see about 75% of symptom alleviation. (32:15) But can it make the problem worse by increasing dysbiosis? Important gut health superfoods are high-FODMAP: Vegetables include: Asparagus, Brussels sprouts, cauliflower, cabbage, chicory leaves, globe and Jerusalem artichokes, garlic, onions, leeks, mushrooms, and snow peas Fruits include: Apples, apricots, cherries, figs, mangoes, nectarines, peaches, pears, plums, and watermelon Legumes and pulses include: Baked beans, black-eyed peas, broad beans, butter beans, chickpeas, kidney beans, lentils, and split peas All these foods are great for the gut microbiome! See Sarah's Gut Health Guidebook and Gut Health Cookbook for a deep dive on all of these. Because many FODMAPs have prebiotic actions, there is concern that their dietary restriction leads to dysbiosis with health consequences!. Studies do show that low-FODMAP diets both in healthy individuals and in IBS cause dysbiosis! This study randomly allocated twenty-seven IBS and six healthy subjects into one of two 21-day provided diets, differing only in FODMAP content. And then crossed them over to the other diet with ≥21-day washout period. Fecal indices were similar in IBS and healthy subjects during habitual diets.  It concluded that diets differing in FODMAP content have marked effects on gut microbiota composition. And the low FODMAP diet should not be recommended for asymptomatic populations. This study associated a low-FODMAP diet with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects—the low FODMAP diet associated the reduction in Bifidobacterium and breath hydrogen in healthy volunteers. Another study in IBD shows a low FODMAP diet helped symptoms but had a significantly lower abundance of Bifidobacterium adolescentis, Bifidobacterium longum, and Faecalibacterium prausnitzii.    High FODMAP & Prebiotic Supplementation Diets Interestingly, there have been studies looking at high-FODMAPs and prebiotic supplementation diets for IBS. (35:50) Studies consistently demonstrate the clinical effectiveness of the low FODMAP diet in patients with IBS. However, the impact on the microbiotaone is an unintentional consequence of this dietary intervention.  This leads to an interesting paradox! Increasing luminal Bifidobacteria through probiotic supplementation is associated with a reduction in IBS symptoms. However, the low FODMAP diet has clinical efficacy but markedly reduces luminal Bifidobacteria concentration. Similarly, another study found no differences in severity of abdominal pain, bloating and flatulence, and QoL scores between prebiotics and placebo.  Conclusions Food intolerance can cause IBS. In this case, identifying exact triggers through elimination and challenge is important. That way, you aren't cutting out important foods. Dysbiosis causes the vast majority of the rest. Low-FODMAP may help alleviate symptoms, but it also perpetuates gut dysbiosis. This means every time you eat a FODMAP, you'll get symptoms. They may even worsen over time. Stacy adds that we tend to focus more on what we can take away than add. We need to focus on both sides to ensure our solution to symptom relief isn't furthering the problem causing those symptoms. What to Do: The Problem of a Low-FODMAP Diet Support gut health and go slow! (42:30) Be sure to keep FODMAP consumption low enough that symptoms are tolerable while supporting gut health.  Consume lots of veggies, fruits and mushrooms (Episodes 281, 286, 304, 307, 335, 346, 373, 392, 424, & 435).  Eat nuts and seeds in moderation (Episodes 413 & 452). Use EVOO as your go-to fat (Episodes 326 and 414). Be sure you're consuming lots of fish, shellfish, or a fish oil supplement (Episodes 366, 415, & 451) Avoid prebiotic-enhanced foods, inulin, and overdoing one type of fiber. It's best to get fiber from whole-food sources. Be sure you're getting enough sleep, activity and are effectively managing stress. A good Bacillus-based probiotic like Just Thrive can help immensely! Plus fermented foods (not the same probiotic species, so both are important). Bacillus species (like what are in Just Thrive) are keystone species known to create a gut environment conducive to the growth of Lactobacillus and Bifidobacterium. It's also important to gradually increase high-FODMAP foods but go slow.   Final Thoughts Stacy really appreciates their ability to revisit these topics and the science as it changes. (50:45) This show is all about facts, not opinions, and sometimes those facts can change. Stacy loves the idea of dieting in terms of what we can add to it to better ourselves, rather than focus solely on what we could take away.  Sarah highly recommends her books, The Gut Health Guidebook and The Gut Health Cookbook, for even more information about the gut microbiome and combating the problem with a low-FODMAP diet. This show was sponsored by Just Thrive, which Stacy and Sarah both use and love! Remember, use code THEWHOLEVIEW at checkout for 15% off.  Be sure to head over to Patreon for even more from Stacy and Sarah! It's a great way to connect with them and get first in line for answers to whatever questions you might have!

Join me today at 10:00am CT on Mojo50 Radio. My guest Natasha Trenev, Founder & President of @natrenprobiotics_ and probiotic pioneer will have an open discussion on the topic of "How Gut Health Impacts The Risk Of Disease".Listen @ 10:00am CT on:www.mojo50.comHeart RadioiTunesAppleLive streaming via:YouTube and Facebook:https://www.facebook.com/Therichsolution/https://www.youtube.com/c/therichsolution

Join me today at 10:00am CT on Mojo50 Radio. My guest Natasha Trenev, Founder & President of @natrenprobiotics_ and probiotic pioneer will have an open discussion on the topic of "How Gut Health Impacts The Risk Of Disease".Listen @ 10:00am CT on:www.mojo50.comHeart RadioiTunesAppleLive streaming via:YouTube and Facebook:https://www.facebook.com/Therichsolution/https://www.youtube.com/c/therichsolution

Kate and Emma kick off the new podcast rebrand with an episode dedicated to all things gut health. We get nerdy about Lactobacilli, endocannabinoids, and everything else the sea moss girlies should know about the GI tract. We give you a run down of how to properly read a probiotic supplement -- from the CFU count to key disclaimers from the Food and Drug Administration. Kate and Emma leave you with their favorite fermented foods and hope you all are excited to join this new wellness community in 2021. Kate Glavan -- instagram.com/kateglavan/ Emma Roepke -- instagram.com/emma.roepke/ Sea Moss Girlies -- instagram.com/seamossgirlies/ Sea Moss Girlies on Patreon -- https://www.patreon.com/seamossgirlies Sea Moss Life Community Platform on Geneva https://links.genevachat.com/invite/03fa1998-a28f-4cc1-8bae-95dec9ecf0e6 --- Support this podcast: https://anchor.fm/wtf-is-sea-moss/support Learn more about your ad choices. Visit podcastchoices.com/adchoices

#therichsolution #motherofprobiotics #natrenconcepts“Anti-carcinogenic and Antitumor properties of selected strains of Bacteria”Join me today at 10:00am CT on Mojo50 Radio. My guest Natasha Trenev, Founder & President of @natrenprobiotics_ and probiotic pioneer. She will speak to the topic of “Anti-carcinogenic and Antitumor properties of selected strains of Bacteria”Here's what you'll learn:*Learn how to stimulate your immune response to have anti-carcinogenic-antitumor effect. *How you can help eliminate the production of toxic, carcinogen or mutagenic compounds from one's daily diet.*Learn what is associated with a resistance to a wide range of age-related diseases including colorectal cancer.Listen @ 10:00am CT on:www.mojo50.comHeart RadioiTunesAppleLive streaming via:YouTube and Facebook:https://www.facebook.com/Therichsolution/https://www.youtube.com/c/therichsolution

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.08.331256v1?rss=1 Authors: Higurashi, S., Tsukada, S., Nakano, S., Mori, I., Noma, K. Abstract: Diet is proposed to affect brain aging. However, the causality and mechanism of dietary effects on brain aging are still unclear due to the long time scales of aging. The nematode Caenorhabditis elegans (C. elegans) has led aging research because of its short lifespan and easy genetic manipulation. When fed the standard laboratory diet, Escherichia coli (E. coli), C. elegans experiences an age-dependent decline in temperature-food associative learning, called thermotaxis. To address if diet ameliorates this decline, we screened 35 different lactic acid bacteria as alternative diets. We found that Lactobacilli in a clade enriched with heterofermentative bacteria ameliorated age-dependent decline. On the other hand, homofermentative Lactobacillus species did not show this beneficial effect. Lactobacilli affected the thermotaxis of aged animals through DAF-16, an ortholog of mammalian FOXO transcription factor, while the effect on the thermotaxis was independent of the lifespan and locomotion. Our results demonstrate that diet can impact brain aging without changing the lifespan and that bacterial screen using C. elegans is a powerful approach to investigate age-dependent behavioral decline. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.10.291781v1?rss=1 Authors: Bonnardel, F., Haslam, S. M., Dell, A., Feizi, T., Liu, Y., Tajadura-Ortega, V., Akune, Y., Sykes, L., Bennett, P. R., MacIntyre, D. A., Lisacek, F., Imberty, A. Abstract: Lectins, such as adhesins and toxins, are carbohydrate-binding proteins that recognise glycans of cells and their secretions. While mediation of microbe-microbe and microbe-host interactions by lectins has long been recognised in the lung and gut, little is known about those in the vagina, where such interactions are implicated in health and various disease states. These include sexually transmitted infections, cervical cancer and poor pregnancy outcomes such as preterm birth. In this study, the curated UniLectin3D database was used to establish a lectin classification based primarily on taxonomy and protein 3D structure. The resulting 109 lectin classes were characterised by specific Hidden Markov Model (HMM) profiles. Screening of microbial genomes in the UniProt and NCBI NR sequence databases resulted in identification of >100 000 predicted bacterial lectins available at unilectin.eu/bacteria. Screening of the complete genomes of 90 isolates from 21 vaginal bacterial species showed that the predicted lectomes (ensemble of predicted lectins) of Lactobacilli associated with vaginal health are substantially less diverse than those of pathogens and pathobionts. Both the number of predicted bacterial lectins, and their specificities for carbohydrates correlated with pathogenicity. This study provides new insights into potential mechanisms of commensal and pathogen colonisation of the reproductive tract that underpin health and disease states. Copy rights belong to original authors. Visit the link for more info

By Manal Mohammed for The ConversationFermented foods have become very popular, thanks to claims about their nutritional properties and reported health benefits, such as improving digestion, boosting immunity and even helping people lose weight. Some of the most popular fermented foods include kefir, kombucha, sauerkraut, tempeh, natto, miso, kimchi and sourdough bread.But though these fermented foods might offer us many health perks, most people aren't aware that they might not work for everyone. For some people, fermented foods might cause serious health issues.Fermented foods are loaded with microorganisms, such as live bacteria and yeast (known as probiotics). However, not all microorganisms are bad. Many, like probiotics, are harmless and are even beneficial to us.During the process of fermentation, probiotics convert carbohydrates (starch and sugar) into alcohol and/or acids. These act as a natural preservative and give fermented foods their distinctive zest and flavour. Many factors affect fermentation, including the type of probiotic, the primary metabolites these microbes produce (such as lactic acid, or certain amino acids), and the food undergoing fermentation. For example, probiotic yogurt is produced by fermenting milk, most commonly with lactic acid bacteria that produce lactic acid.Fermented foods contain high amounts of probiotics, which are generally considered safe for the majority of people. In fact, they've been shown to have anti-oxidant, anti-microbial, anti-fungal, anti-inflammatory, anti-diabetic and anti-atherosclerotic activity. However, some people might experience severe side effects after consuming fermented foods.1. BloatingThe most common reaction to fermented foods is a temporary increase in gas and bloating. This is the result of excess gas being produced after probiotics kill harmful gut bacteria and fungi. Probiotics secrete antimicrobial peptides that kill harmful pathogenic organisms like Salmonella and E. Coli.A recent study showed this antimicrobial effect of probiotic Lactobacilli strains found in commercial yogurt. Although bloating after eating probiotics seems to be a good sign that the harmful bacteria are being removed from the gut, some people might experience severe bloating, which can be very painful.Drinking too much kombucha can also lead to excess sugar and calorie intake, which may also lead to bloating and gas.2. Headaches and migrainesFermented foods rich in probiotics – including yogurt, sauerkraut and kimchi – naturally contain biogenic amines produced [during fermentation]. Amines are created by certain bacteria to break down the amino acids in fermented foods. The most common ones found in probiotic-rich foods include histamine and tyramine.Some people are sensitive to histamine and other amines, and may experience headaches after eating fermented foods. Because amines stimulate the central nervous system, they can increase or decrease blood flow, which can trigger headaches and migraines. One study found that low-histamine diets reduced headaches in 75% of participants. Taking a probiotic supplement might be therefore preferred.3. Histamine intoleranceHistamine is plentiful in fermented foods. For most, our body's specific enzymes will naturally digest them. However, some people don't produce enough of these enzymes. This means histamine won't be digested and will instead be absorbed into the bloodstream.This can cause a range of histamine intolerance symptoms. The most common are itching, headaches or migraines, runny nose (rhinitis), eye redness, fatigue, hives and digestive symptoms include diarrhoea, nausea and vomiting.However, histamine intolerance can also cause more severe symptoms, including asthma, low blood pressure, irregular heart rate, circulatory collapse, sudden psychological changes (such as anxiety, aggressiveness, dizziness and lack of concentration) and sleep disorders.4. Food-borne illnessWhile most fermented foods are saf...