Podcasts about Sucrose

Episode 2622 - Vinnie Tortorich and Anna Vocino discuss why sugar is sugar, what is a "bonk", what has changed in Vinnie's digital diet, and more. https://vinnietortorich.com/2025/03/sugar-is-sugar-episode-2622 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - Sugar Is Sugar Do we need sugar? (4:00) You need fat and protein for energy and building every cell in your body. You need Anna's spices more! (5:00) Anna's Eat Happy Kitchen spices are on sale for a short time. Use code BOGO25. People get militant about sugar. (15:00) Sucrose, fructose, starches—it's all simple sugars. Honey is sugar. What is a "sugar trickle"? (17:00) Vinnie explains fat burning during sports and what a "bonk" is. Vinnie figured out how to do a sugar trickle during ultra races. The body only needs about 2 tsp of glucose for normal activity. (31:00) Anna gets asked all the time for a specific meal plan. (38:45) She has always loved the ease and flexibility of NSNG as a voice of reason. Her question to people is: why do you feel you can't trust yourself? Resistant starches: Anna asks what the deal is about them and whether they are related to a sugar trickle. Yes, they can be absorbed more slowly, but the benefit is the same as smoking a cigarette with or without a filter. (45:30) Update on Vinnie's “digital diet.” (50:30) Vinnie is knocking time off of his screen time. Have you tried limiting screen time? More News If you are interested in the NSNG® VIP group, register here! Don't forget to check out Serena Scott Thomas on Days Of Our Lives on the Peacock channel.  “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook is available!  You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! There's a new NSNG® Foods promo code you can use! The promo code ONLY works on the NSNG® Foods website, NOT on Amazon. https://nsngfoods.com/   PURCHASE  DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:

Ellen Kamhi talks with Troy Duell, an influential health educator and the founder of Centurion Labs. With a decade of experience, he leverages his background in professional sports, teaching, and pharmaceuticals to promote accessible healthcare. His commitment to evidence-based health information has established him as a trusted figure in health education. Duell holds degrees from the University of Alabama and Regent University.  He talks about the impact of sugar consumption on our physical and mental health.

Jackie's lonely deep-space post enjoys delicious company.Based on a post by Alizzia. Listen to the Podcast at Steamy Stories.Jackie awoke to a twinkling, navy-blue night. She lay still, perceived the idle murmer of gulls and surf, the sweet air, the soft and runny sand against her back. With every little rush of the surf, a liquid touch caressed her. Startlingly chill. Goosebumps prickled her naked form. She pulled a long, resuscitating breath, sat up.She nearly gasped. Out on the surf, submerged to the dimpled saddle of his hips, stood a bare and strapping figure. Head tipped to the moon, he raised and clasped corded hands, stretched. He twisted, hummed as he arched the broad, inverted triangle of his lats. Yawning luxuriantly, he turned, dropped his arms, smiled at Jackie.Jackie's pulse fluttered. She returned the crinkled hazel eyes' smile. The figure blushed a hint, turned a bashful eye to the sea. He approached. Surf split and foamed about his hips, thighs, knees, ankles. All softly corded, olive, and bare.He stopped inches from Jackie's toes, let his gaze drag over her, slow. She blushed in return, twisted a little, pulled and bent her knees to touch. Responding, his eyes flicked to her face, stopped there. Though not a turn of betrayed sentiment showed on his lips, a soft bundle of creases remained at the corners of his eyes, somehow more intense. He lingered on her mouth, nose, eyes, canted his head just a hint. A hoarse, longing sigh rose from his chest.Some melted excitement splashed into Jackie's chest and belly. Returning the gaze in full measure, she straightened her legs, arms, lay back on the sand. She raised a challenging brow.Slow, the figure knelt, touched one knee to the beach, then the other. He straddled just one of Jackie's legs, bent, placed heavy hands beside her head. Jackie could hear the wet sand squish under his weight. He bent ever so close, stopped, just breathed. Not a slip of skin touched between them. Droplets fell from his locks and long nose, fell just inches before rolling down Jackie's cheeks. He smelt of salt and earth.Jackie's lips parted involuntarily, asymmetrically. Never breaking her gaze, she stretched, wriggled just a bit, tilted her groin and chin. She heard the figure's pupils dilate, heard his shuddering breath, sensed his heavy arousal. A small smile of glee split her face. She squirmed in the sand beneath him, like a sea star, free beneath his hanging weight. Then, suddenly deadly serious, she stopped. With dearest care, she shifted just a little, pulled the inside of a smooth thigh to meet his knee. The figure shuddered, shut his eyes. Jackie struck, pushed her lips into his. For a moment, she could taste the warmth, the salt. Then, the world spun.The figure disappeared. The stars went out. The black sky fell away. Jackie awoke to a riveted, titanium ceiling studded with white lights. She flailed momently, gasping wetly. Tubes hung before her face, wet with the spit of her own trachea. Pressure lifted from her wrists, ankles, and abdomen. She began to float from the padded pod where she lay.Jackie's clumsy fingers found rails on either edge of the pod. She held herself within, panted. She swallowed dryly, blinked, surveyed the pod, her white sleep shorts and top, the room about her. After a moment, she groaned in recognition and disappointment. Any arousal she'd experienced had flown with her dream, left her with naught but a sodden crotch in a chilly room."Good morning, Specialist Jaqueline Kent," said a voice, at once sonorous and very dull.Jackie tried to sit up and look over the side of the bed. The inertia of the action strained her fingers. Her hands split from the rail. She floated from the bed, frowned.Across the room was a crop-haired man in red. His cotton jumpsuit strained where it failed to accommodate his chest and back. He had cold, blue eyes and a pointed nose. He held onto a support rail, feet firmly affixed to the vaguely-concave floor in magnet boots."Who the fu..." coughed Jackie, barely audible. She rasped. "The fuck are you?" She inadvertently turned upside down in the microgravity, crossed her arms over her floating tits."My pardon, Specialist Kent. My designation is Sam.""You're..." said Jackie, trying to find a more dignified stance. She failed, ended up sort of weakly kicking off the side wall. She made a face as she clipped the stasis pod, wheeled into Sam. Her face collided with his broad chest. He caught her there. For a moment, Jackie's cheek and nose pressed into him. He was firm, but soft. He smelled of soap and salt."You're a service unit, an organic android?" she said, frowning, as Sam pulled her away from him."Indeed.""Why isn't this place being spun for gravity?" raged Jackie, shuffling from his grasp. Strong fingers released from her upper arms."The habitat is spun for only eight hours of the 24-hour cycle, per regulated health minimums. Generator and battery capacity are prioritized for the lighthouse array, rather than gravity rotors. The next spin commences tonight, in several minutes," said Sam, smiling thinly. "For now, please accept these mag boots.""Fine," said Jackie, cold. She bumped against the wall, struggled to pull a boot on. The other floated away. She made a face, huffed, weak from stasis sleep. "Please, allow me," said Sam. For just a moment, Jackie twisted her face as if to protest, but relented. She moved close, allowed the android to wrap an arm around each of her calves in turn, slip a boot over the foot, and strap it tight. For a moment, she relaxed, felt the long hands wrap near-entirely round her bare ankles. They were firm, but not rough. Sam moved away. "There."Jackie tentatively pushed away, set a foot to the floor, felt it stick. "Thanks," she said, quietly."Allow me to show you around the lighthouse. Afterwards, you may recuperate. It will only take a moment. The station is not large, and I understand by your Company service record that you have served in this role before.""There wasn't an android on my last lighthouse. I do this job because I like the solitude."Sam looked genuinely regretful. "I am sorry. You must understand I was attached to this station by the company. I am their property.""Yeah, yeah," said Jackie, seeing his face. A spike of empathy broke through her grumpiness. "You don't seem like bad company, anyway. What model are you?" she said, as Sam opened the hatch for them to exit."I am a Serault Corporation Ceres-6," he said, stepping through. Jackie followed. The concave floor of the room beyond was double-walled transparent alloy. It acted as a gigantic window out onto the red and purple nebula which the lighthouse was meant to warn of. Along the walls, set so one might look down into the nebula, were leather benches, a few pod chairs, and a bed with microgravity webbing, all somewhat worn. Crimson light played over the white upholstery and sheets.Jackie looked over the living quarters, far nicer than she'd had before. She gaped at the nebula for a moment, watched a streak of magenta light cross Sam's eyes and face. "So, you're one of those white-blooded ones?""My internal serum is a sucrose base. It serves modified roles in all my body fluids. It is indeed an off-white.""Sucrose? A real sweetie, huh?""If indeed it were to be tasted, my serum would taste of sugar." He looked her in the eyes, terribly sincere.Jackie looked away, grinned uncomfortably. "Right. Have any other special features?" she said, sarcastic."As Ceres-6 models are designed for small crew missions, our personality precepts are mutable. We change in reaction or in request to facilitate maximum compatibility.""Ah, well. Good to know." Jackie looked about awkwardly, arms crossed. "I take it this is my room?""Indeed, this is the lighthouse keeper's room," he blinked at her, slow."And where do you sleep?""Though I do not often enter my hibernation cycle, I have a pod in the crew maintenance room we just exited."Jackie suddenly uncrossed her arms, waved one about. "Listen, do you need to stare me straight in the eyeballs all the time? It's freaking me out.""Would you prefer I focus on a different portion of your body?" said Sam. He concernedly looked at her left foot."Like, shit. No. Just let your eyes wander like a normal person, okay?""Understood," said Sam. He glanced at her eyes, then about the room, then down into the floor-window."A little less wildly, maybe.""Yes, Specialist Kent." His eyes flitted over Jackie, focused momently on the nipples poking through her airy sleep top. Jackie crossed her arms, blushed. "And call me Jackie, not Specialist Kent.""Understood, Jackie.""And smile a bit more.""Of course," he said, doing so. Jackie shivered, not from the chill air. The lines which pulled about the android's eyes and nose bridge turned the cold face quite warm. It stayed that way."Well," said Jackie, hesitating. "We're getting on better already," she said, only half as sarcastic as she meant. "Can we continue the tour? I could use a shower.""Of course." He continued to a hatch on the other side of the room. Jackie stepped through as well. They entered a circular room with a ladder in the center. The walls were ringed with computer panels and other hatches."This is the primary communication room. Here, you-""Sam, I know how to use the comms.""My apologies," he said. "This hatch leads to the EVA room. This one to the galley. This one to life support. The ladder leads up to the secondary systems and down to engineering.""I take it life support has the shower?""Indeed.""Great. Anything else?""No. We commence operation tomorrow morning, approximately an hour after the eight-hour spin." He broke off for a moment, canted his head. His eyes trailed over Jackie's bare abdomen, likely by chance. She squirmed, regardless. Sam raised his eyebrows, continued. "The spin, which I believe should commence now."There was a jerk, a hollow whine in the hull of the station, a rush in Jackie's ears. Jackie and Sam slowly settled under the centrifugal forces. Jackie adjusted her shorts, surreptitiously. "I'm going to shower.""There are requisite uniforms and undergarments waiting for you.""Gee, thanks for laying out my underwear.""Of course, Jackie."Jackie shook her head, kicked off the mag boots, stomped to the life support bay. She shut the hatch with a good deal of force. The bathroom was behind a secondary hatch, near the spare air purification tanks and the waterless laundry engine. It was stark, shiny white, floored with nobly grip tiles. There were indeed clothes laid out for her: A red jumpsuit and white boyshorts. Jackie passed them just a glance before dropping her shorts and top. Naked, she passed the small mirror, sneered at her baggy eyes, her body, depilated for stasis sleep.She stepped into the shower. A touch panel reading "Shower Ration: 2 Minutes," met her."Same old station-life," she groaned, punched the Start key.A vertical shower hit from above. Mist quickly filled the room. Jackie moaned for the heat, turned her head and chest to face the stream. Little rivulets poured from her nose, chin, nipples. At these she looked askance, gently surprised. She cupped, rubbed one between thumb and forefinger experimentally, sighed a little. She repeated this with both, sighed a lot. Doing so, suddenly quite determined, she stepped back and leaned back, pressed her rump against the white wall. One hand, the right one, slipped between her hairless legs, which she widened just sufficiently. They wobbled a bit, weak from stasis. She leaned harder against the wall, slipped a middle finger over and through her dripping vulva, split the lips, found it dripping inside, too. The left hand joined, found the clit, elicited a hum, a bitten lip. Several wet seconds later, a groan. Jackie's face tipped upwards. Her thighs twitched. Droplets hit her screwed-up eyelids, her open mouth.The water stopped abruptly. Jackie jerked upright. "Motherfucker," she said, a cry fading into a mumble. She leaned through the steam, slightly pigeontoed, red the touch panel. It said, "Time until next Shower Ration: 18 hours." Jackie rubbed her temples, groaned resignedly. The cold of the station was already seeping into the shower. Quickly, she dried, performed her remaining ablutions, threw on the insulated red jumpsuit over still-aching nipples.Jackie emerged to find Sam in the life-support bay. He was shirtless, jumpsuit rolled at the waste, supine beneath a large conduit emitting steam. Droplets rolled over his long fingers and corded forearms, dripped and slid over an expanse of blond-furred chest. Veins stood out in his neck and arms, swollen from the effort of having just slotted a hefty filter into place. As Jackie approached, he turned."Jackie," he said, emerging carefully from under the conduit. He panted gently, lips parted just a tad. They were pink, creased. Human. "How are we?""I'm fine, thanks," said Jackie, forcibly pulling her eyes to his. She looked for a moment longer, watched a vein pulse on his temple. "If you don't mind me saying, you're damn realistic, aren't you?""I am, on the exterior, functionally and visually indistinguishable from a human man.""Yup," said Jackie, moving to leave."Jackie?"She turned back a moment. "Yes?""Is the station too cold for your comfort?" His eyes brows, cream and near-invisible, were arched in concern.Jackie squinted, raised an eyebrow. "No. It's fine.""Good. And, do make sure to have the appropriate post-stasis ration packs. I have concerns your flight here has left you low on muscle mass."Jackie turned away. "Yeah."She opened the hatch to her quarters, shut it with a huff. One protein pack later, she had stripped off her jumpsuit, dead asleep.Hours later, Jackie woke to a crimson nebulaic glow. She floated, bleary, in the microgravity webbing. The vibrating hum of the spin-rotors had died. Now, there was merely silence. Dully, Jackie moved to turn over under the webbing. As her thighs shifted, she felt a tingling wetness from some dream she couldn't remember. Idly, half asleep, she let a fingertip creep down her belly, trace over the soaked groin of her shorts, begin to prod, massage. She hummed, rubbed her cheek into the netting.Nearby, a hatch creaked open. Jackie jerked awake, hang back her hand, froze."Ready to get to work, Specialist Jackie?"Jackie groaned. "Yup," she said. Sam nodded, smiled, retreated into the comms room. The hatch clacked shut.Only after clambering out of the sleep webbing did Jackie realize her floating tits had been in full view. The Corporation had some odd opinions about bras in space. Jackie shook her head. "Chill, girl. Robot doesn't care."The proceeding five hours were a floating blur. Jackie stood in the comms room, directed ship after ship in non-collision courses around the nebula. The job was a steep and constant series of calls and responses to incoming and waiting craft. Sam assisted."Astroliner 313, after well veer, climb straight ahead five degrees Kepler. Thank you.""Jackie, we have a Corsican military craft requesting expedited access," said Sam."Tell him to follow the greens and stand by for expedite.""EES Pearl River is expressing a complaint.""Send them the docs. They can deal with the Company." She changed channels. "Yes, Arrowtine Sirius, you have permission to take route bravo in five. Thank you.""Jackie, I'm directing Designate 476 to hold. Their cargo requires maximum berth.""Thanks, Sam."Sam smiled thinly at her. He had started doing that more often. His eyes stayed crinkled kindly, when he did. Jackie kept watching him.Abruptly, Sam frowned. "Jackie, we have an error.""What?""New connections are timing out. We have a receiver down from d

Jackie's lonely deep-space post enjoys delicious company.Based on a post by Alizzia. Listen to the Podcast at Steamy Stories.Jackie awoke to a twinkling, navy-blue night. She lay still, perceived the idle murmer of gulls and surf, the sweet air, the soft and runny sand against her back. With every little rush of the surf, a liquid touch caressed her. Startlingly chill. Goosebumps prickled her naked form. She pulled a long, resuscitating breath, sat up.She nearly gasped. Out on the surf, submerged to the dimpled saddle of his hips, stood a bare and strapping figure. Head tipped to the moon, he raised and clasped corded hands, stretched. He twisted, hummed as he arched the broad, inverted triangle of his lats. Yawning luxuriantly, he turned, dropped his arms, smiled at Jackie.Jackie's pulse fluttered. She returned the crinkled hazel eyes' smile. The figure blushed a hint, turned a bashful eye to the sea. He approached. Surf split and foamed about his hips, thighs, knees, ankles. All softly corded, olive, and bare.He stopped inches from Jackie's toes, let his gaze drag over her, slow. She blushed in return, twisted a little, pulled and bent her knees to touch. Responding, his eyes flicked to her face, stopped there. Though not a turn of betrayed sentiment showed on his lips, a soft bundle of creases remained at the corners of his eyes, somehow more intense. He lingered on her mouth, nose, eyes, canted his head just a hint. A hoarse, longing sigh rose from his chest.Some melted excitement splashed into Jackie's chest and belly. Returning the gaze in full measure, she straightened her legs, arms, lay back on the sand. She raised a challenging brow.Slow, the figure knelt, touched one knee to the beach, then the other. He straddled just one of Jackie's legs, bent, placed heavy hands beside her head. Jackie could hear the wet sand squish under his weight. He bent ever so close, stopped, just breathed. Not a slip of skin touched between them. Droplets fell from his locks and long nose, fell just inches before rolling down Jackie's cheeks. He smelt of salt and earth.Jackie's lips parted involuntarily, asymmetrically. Never breaking her gaze, she stretched, wriggled just a bit, tilted her groin and chin. She heard the figure's pupils dilate, heard his shuddering breath, sensed his heavy arousal. A small smile of glee split her face. She squirmed in the sand beneath him, like a sea star, free beneath his hanging weight. Then, suddenly deadly serious, she stopped. With dearest care, she shifted just a little, pulled the inside of a smooth thigh to meet his knee. The figure shuddered, shut his eyes. Jackie struck, pushed her lips into his. For a moment, she could taste the warmth, the salt. Then, the world spun.The figure disappeared. The stars went out. The black sky fell away. Jackie awoke to a riveted, titanium ceiling studded with white lights. She flailed momently, gasping wetly. Tubes hung before her face, wet with the spit of her own trachea. Pressure lifted from her wrists, ankles, and abdomen. She began to float from the padded pod where she lay.Jackie's clumsy fingers found rails on either edge of the pod. She held herself within, panted. She swallowed dryly, blinked, surveyed the pod, her white sleep shorts and top, the room about her. After a moment, she groaned in recognition and disappointment. Any arousal she'd experienced had flown with her dream, left her with naught but a sodden crotch in a chilly room."Good morning, Specialist Jaqueline Kent," said a voice, at once sonorous and very dull.Jackie tried to sit up and look over the side of the bed. The inertia of the action strained her fingers. Her hands split from the rail. She floated from the bed, frowned.Across the room was a crop-haired man in red. His cotton jumpsuit strained where it failed to accommodate his chest and back. He had cold, blue eyes and a pointed nose. He held onto a support rail, feet firmly affixed to the vaguely-concave floor in magnet boots."Who the fu..." coughed Jackie, barely audible. She rasped. "The fuck are you?" She inadvertently turned upside down in the microgravity, crossed her arms over her floating tits."My pardon, Specialist Kent. My designation is Sam.""You're..." said Jackie, trying to find a more dignified stance. She failed, ended up sort of weakly kicking off the side wall. She made a face as she clipped the stasis pod, wheeled into Sam. Her face collided with his broad chest. He caught her there. For a moment, Jackie's cheek and nose pressed into him. He was firm, but soft. He smelled of soap and salt."You're a service unit, an organic android?" she said, frowning, as Sam pulled her away from him."Indeed.""Why isn't this place being spun for gravity?" raged Jackie, shuffling from his grasp. Strong fingers released from her upper arms."The habitat is spun for only eight hours of the 24-hour cycle, per regulated health minimums. Generator and battery capacity are prioritized for the lighthouse array, rather than gravity rotors. The next spin commences tonight, in several minutes," said Sam, smiling thinly. "For now, please accept these mag boots.""Fine," said Jackie, cold. She bumped against the wall, struggled to pull a boot on. The other floated away. She made a face, huffed, weak from stasis sleep. "Please, allow me," said Sam. For just a moment, Jackie twisted her face as if to protest, but relented. She moved close, allowed the android to wrap an arm around each of her calves in turn, slip a boot over the foot, and strap it tight. For a moment, she relaxed, felt the long hands wrap near-entirely round her bare ankles. They were firm, but not rough. Sam moved away. "There."Jackie tentatively pushed away, set a foot to the floor, felt it stick. "Thanks," she said, quietly."Allow me to show you around the lighthouse. Afterwards, you may recuperate. It will only take a moment. The station is not large, and I understand by your Company service record that you have served in this role before.""There wasn't an android on my last lighthouse. I do this job because I like the solitude."Sam looked genuinely regretful. "I am sorry. You must understand I was attached to this station by the company. I am their property.""Yeah, yeah," said Jackie, seeing his face. A spike of empathy broke through her grumpiness. "You don't seem like bad company, anyway. What model are you?" she said, as Sam opened the hatch for them to exit."I am a Serault Corporation Ceres-6," he said, stepping through. Jackie followed. The concave floor of the room beyond was double-walled transparent alloy. It acted as a gigantic window out onto the red and purple nebula which the lighthouse was meant to warn of. Along the walls, set so one might look down into the nebula, were leather benches, a few pod chairs, and a bed with microgravity webbing, all somewhat worn. Crimson light played over the white upholstery and sheets.Jackie looked over the living quarters, far nicer than she'd had before. She gaped at the nebula for a moment, watched a streak of magenta light cross Sam's eyes and face. "So, you're one of those white-blooded ones?""My internal serum is a sucrose base. It serves modified roles in all my body fluids. It is indeed an off-white.""Sucrose? A real sweetie, huh?""If indeed it were to be tasted, my serum would taste of sugar." He looked her in the eyes, terribly sincere.Jackie looked away, grinned uncomfortably. "Right. Have any other special features?" she said, sarcastic."As Ceres-6 models are designed for small crew missions, our personality precepts are mutable. We change in reaction or in request to facilitate maximum compatibility.""Ah, well. Good to know." Jackie looked about awkwardly, arms crossed. "I take it this is my room?""Indeed, this is the lighthouse keeper's room," he blinked at her, slow."And where do you sleep?""Though I do not often enter my hibernation cycle, I have a pod in the crew maintenance room we just exited."Jackie suddenly uncrossed her arms, waved one about. "Listen, do you need to stare me straight in the eyeballs all the time? It's freaking me out.""Would you prefer I focus on a different portion of your body?" said Sam. He concernedly looked at her left foot."Like, shit. No. Just let your eyes wander like a normal person, okay?""Understood," said Sam. He glanced at her eyes, then about the room, then down into the floor-window."A little less wildly, maybe.""Yes, Specialist Kent." His eyes flitted over Jackie, focused momently on the nipples poking through her airy sleep top. Jackie crossed her arms, blushed. "And call me Jackie, not Specialist Kent.""Understood, Jackie.""And smile a bit more.""Of course," he said, doing so. Jackie shivered, not from the chill air. The lines which pulled about the android's eyes and nose bridge turned the cold face quite warm. It stayed that way."Well," said Jackie, hesitating. "We're getting on better already," she said, only half as sarcastic as she meant. "Can we continue the tour? I could use a shower.""Of course." He continued to a hatch on the other side of the room. Jackie stepped through as well. They entered a circular room with a ladder in the center. The walls were ringed with computer panels and other hatches."This is the primary communication room. Here, you-""Sam, I know how to use the comms.""My apologies," he said. "This hatch leads to the EVA room. This one to the galley. This one to life support. The ladder leads up to the secondary systems and down to engineering.""I take it life support has the shower?""Indeed.""Great. Anything else?""No. We commence operation tomorrow morning, approximately an hour after the eight-hour spin." He broke off for a moment, canted his head. His eyes trailed over Jackie's bare abdomen, likely by chance. She squirmed, regardless. Sam raised his eyebrows, continued. "The spin, which I believe should commence now."There was a jerk, a hollow whine in the hull of the station, a rush in Jackie's ears. Jackie and Sam slowly settled under the centrifugal forces. Jackie adjusted her shorts, surreptitiously. "I'm going to shower.""There are requisite uniforms and undergarments waiting for you.""Gee, thanks for laying out my underwear.""Of course, Jackie."Jackie shook her head, kicked off the mag boots, stomped to the life support bay. She shut the hatch with a good deal of force. The bathroom was behind a secondary hatch, near the spare air purification tanks and the waterless laundry engine. It was stark, shiny white, floored with nobly grip tiles. There were indeed clothes laid out for her: A red jumpsuit and white boyshorts. Jackie passed them just a glance before dropping her shorts and top. Naked, she passed the small mirror, sneered at her baggy eyes, her body, depilated for stasis sleep.She stepped into the shower. A touch panel reading "Shower Ration: 2 Minutes," met her."Same old station-life," she groaned, punched the Start key.A vertical shower hit from above. Mist quickly filled the room. Jackie moaned for the heat, turned her head and chest to face the stream. Little rivulets poured from her nose, chin, nipples. At these she looked askance, gently surprised. She cupped, rubbed one between thumb and forefinger experimentally, sighed a little. She repeated this with both, sighed a lot. Doing so, suddenly quite determined, she stepped back and leaned back, pressed her rump against the white wall. One hand, the right one, slipped between her hairless legs, which she widened just sufficiently. They wobbled a bit, weak from stasis. She leaned harder against the wall, slipped a middle finger over and through her dripping vulva, split the lips, found it dripping inside, too. The left hand joined, found the clit, elicited a hum, a bitten lip. Several wet seconds later, a groan. Jackie's face tipped upwards. Her thighs twitched. Droplets hit her screwed-up eyelids, her open mouth.The water stopped abruptly. Jackie jerked upright. "Motherfucker," she said, a cry fading into a mumble. She leaned through the steam, slightly pigeontoed, red the touch panel. It said, "Time until next Shower Ration: 18 hours." Jackie rubbed her temples, groaned resignedly. The cold of the station was already seeping into the shower. Quickly, she dried, performed her remaining ablutions, threw on the insulated red jumpsuit over still-aching nipples.Jackie emerged to find Sam in the life-support bay. He was shirtless, jumpsuit rolled at the waste, supine beneath a large conduit emitting steam. Droplets rolled over his long fingers and corded forearms, dripped and slid over an expanse of blond-furred chest. Veins stood out in his neck and arms, swollen from the effort of having just slotted a hefty filter into place. As Jackie approached, he turned."Jackie," he said, emerging carefully from under the conduit. He panted gently, lips parted just a tad. They were pink, creased. Human. "How are we?""I'm fine, thanks," said Jackie, forcibly pulling her eyes to his. She looked for a moment longer, watched a vein pulse on his temple. "If you don't mind me saying, you're damn realistic, aren't you?""I am, on the exterior, functionally and visually indistinguishable from a human man.""Yup," said Jackie, moving to leave."Jackie?"She turned back a moment. "Yes?""Is the station too cold for your comfort?" His eyes brows, cream and near-invisible, were arched in concern.Jackie squinted, raised an eyebrow. "No. It's fine.""Good. And, do make sure to have the appropriate post-stasis ration packs. I have concerns your flight here has left you low on muscle mass."Jackie turned away. "Yeah."She opened the hatch to her quarters, shut it with a huff. One protein pack later, she had stripped off her jumpsuit, dead asleep.Hours later, Jackie woke to a crimson nebulaic glow. She floated, bleary, in the microgravity webbing. The vibrating hum of the spin-rotors had died. Now, there was merely silence. Dully, Jackie moved to turn over under the webbing. As her thighs shifted, she felt a tingling wetness from some dream she couldn't remember. Idly, half asleep, she let a fingertip creep down her belly, trace over the soaked groin of her shorts, begin to prod, massage. She hummed, rubbed her cheek into the netting.Nearby, a hatch creaked open. Jackie jerked awake, hang back her hand, froze."Ready to get to work, Specialist Jackie?"Jackie groaned. "Yup," she said. Sam nodded, smiled, retreated into the comms room. The hatch clacked shut.Only after clambering out of the sleep webbing did Jackie realize her floating tits had been in full view. The Corporation had some odd opinions about bras in space. Jackie shook her head. "Chill, girl. Robot doesn't care."The proceeding five hours were a floating blur. Jackie stood in the comms room, directed ship after ship in non-collision courses around the nebula. The job was a steep and constant series of calls and responses to incoming and waiting craft. Sam assisted."Astroliner 313, after well veer, climb straight ahead five degrees Kepler. Thank you.""Jackie, we have a Corsican military craft requesting expedited access," said Sam."Tell him to follow the greens and stand by for expedite.""EES Pearl River is expressing a complaint.""Send them the docs. They can deal with the Company." She changed channels. "Yes, Arrowtine Sirius, you have permission to take route bravo in five. Thank you.""Jackie, I'm directing Designate 476 to hold. Their cargo requires maximum berth.""Thanks, Sam."Sam smiled thinly at her. He had started doing that more often. His eyes stayed crinkled kindly, when he did. Jackie kept watching him.Abruptly, Sam frowned. "Jackie, we have an error.""What?""New connections are timing out. We have a receiver down from d

In this episode of The Real GI Doc Show, Dr. Gandolfo dives into the lesser-known topic of sucrose intolerance, just in time for the candy-filled festivities of Halloween. Many individuals with irritable bowel syndrome (IBS) experience difficulty digesting certain carbohydrates, including sucrose, commonly known as table sugar. Dr. Gandolfo explores the complexities of disaccharidase deficiency, a condition often overlooked in both diagnosis and treatment. Topics covered in this episode: Understanding sucrose intolerance and its impact on gastrointestinal health. The process of sugar digestion in the body and what goes wrong when sucrose isn't properly broken down. Common symptoms associated with sucrose intolerance, such as bloating, diarrhea, and gas. The prevalence of sucrose intolerance among individuals with IBS and how sucrose intolerance is an underdiagnosed condition. Testing methods for sucrose intolerance, including breath tests and small intestinal biopsies. Treatment options, including dietary modifications and enzyme replacement therapy. The importance of recognizing sucrose intolerance for effective management of IBS symptoms. Dr. Gandolfo also discusses the high sugar content in popular Halloween candies and offers insights into how excessive sugar consumption can affect those with and without sucrose intolerance. References: Intestinal Disaccharidase Deficiency in Adults: Evaluation and Treatment Sucrose intolerance in adults with common functional gastrointestinal symptoms ___ Be sure to subscribe to The Real GI Doc Show for more insights, and reach out with your questions on social media @realgidoc or leave an audio question for Dr. Gandolfo here. Find The Real GI Doc Show on social media, join the newsletter, read Dr. Gandolfo's bio, or ask a question using this link. Royalty Free Music from Tunetank.com Track: A Spooktacular Day by DASAINTZ https://tunetank.com/track/5556-a-spooktacular-day/

Whats the difference between Sugar, glucose, fructose, lactose and all the oses?  And do they make a difference  how your body processes sugar and uses insulin? I dig into all of  this today and more. 

A 360-second podcast that's full of the weird, the wonderful, the profound and the hilarious facts of life on earth.© 2024 Jonathan Clemson & Robin Crossman

High Fructose Corn Syrup's Profits over Health:  Richard Gale & Gary Null PhD Progressive Radio Network, July 24, 2024 There is an unseen culprit hiding in the shadows. It is a toxic poison contained in many of the foods and beverages that we commonly eat. A toxin that has been implicated in causing cancer, diabetes, heart disease, lowered cognitive function, addiction, depression, and obesity. The magicians and alchemists of the corporate food industry have cleverly disguised this ingredient and sing its praises.  If you are waiting for mainstream media to undertake an in-depth investigative report on this topic you will be waiting a long time. Back in 2015 Tufts University's department of nutritional sciences conducted a study published by the American Heart Association that documented the annual rates of global deaths directly due to over-consumption of beverages with high sugar content. The results estimated that 184,000 adults die annually from sugary drinks.  Dr. Gitanjali at Tufts analyzed data documenting sugar-related deaths across 51 countries between 1980 and 2010.  Deaths were compiled according to cardiovascular disease, diabetes and various cancers. Based upon the data, the study concluded that sugar contributed to 45,000 annual deaths from cardiovascular disease, 13,000 deaths from diabetic complications, and 6,450 deaths related to cancer.  Credit Suisse's Research Institute published a scathing report that brought sugar's health risks into sharper focus.  The study revealed that upward to 40% of American healthcare expenditures could be directly tied to overconsumption of sugar in the average American diet.  Today, the US' national addiction to sugar contributes to $1 trillion in healthcare costs annually, which includes coronary heart disease, diabetes and metabolic syndrome. There are numerous studies published in reliable peer-reviewed medical journals associating sugar with each of these life threatening diseases. As far back as 1971, I began writing about the hazards of sugar. In 2002, my documentary Seven Steps to Perfect Health was premiered on PBS stations. During a special appearance on one station's fund drive, I poured sugar out of a bag. The amount I poured equaled the number of teaspoons that an average American teenager consumes daily. My general counsel, David Slater, verified the quantity by proper measurement according to scientific food and diet data.  After the initial airing of this special, I was informed by the station's program director that they could not rebroadcast the performance, even though it was the most successful program during the fund drive. I was informed that the station had received harsh criticism from the sugar industry. The program director explained that the information I presented about sugar's dangers, even though I provided full scientific verification of the facts, ran up against the president of the station board Sharon Rockefeller. I was told she had received a phone call from a sugar-lobbying group representing soft drink makers and sugar manufacturers.  Therefore the station made the decision to pull my program. I was never asked to return to the station. Not surprisingly, a subsequent investigation revealed Sharon Rockefeller sat on Pepsi's board at the time, one of America's largest manufacturers of sweetened soft drinks.    That was my first personal encounter with the political forces supporting sugar. I wrote letters to the sugar industry, the station board and Sharon Rockefeller contesting their suppression of my program and their claim that sugar was unrelated to the declining health of Americans. They were presented with dozens of peer-reviewed studies. However in recent decades, the sweetener industry has undergone a dramatic transformation with the introduction and widespread adoption of high fructose corn syrup (HFCS) throughout our food system. This shift from traditional cane sugar, which dominated my criticism earlier, to fructose corn sugars has led to deep human health and environmental concerns due to its economic benefits for food manufacturers.  High fructose corn syrup was developed in the late 1960s by Japanese scientists who discovered a method to convert glucose from cornstarch into fructose using enzymes. This innovation was spurred by the need to find a cheaper and more versatile sweetener as an alternative to the more labor-intensive production of traditional cane sugar. HFCS is made by milling corn to produce cornstarch. The starch is then hydrolyzed into glucose by adding the enzyme alpha-amylase. Finally the glucose is further processed into fructose. The result is a syrup that typically contains 42-55 percent fructose, with the rest being glucose. Some methods can produce fructose as high as 90 percent.  Today, HFCS production has been so optimized that it has become the most cost-effective and efficient means to produce sweeteners. Monsanto's genetically modified Round-Up Ready corn, enabling the use of more toxic herbicides and pesticides, has now made HFCS the cornerstone of the sugar industry.  However, the shift to HFCS has been fundamentally driven by economics and the agro-chemical industry and has absolutely nothing to do with creating a healthier sugar.  Since corn is one of the most extensively cultivated crops in the United States, which is heavily subsidized by the government, it has provided an enormous, inexpensive supply of the raw material needed for HFCS production. In addition, the enzymatic conversion process can result in a high yield of sweetener from a relatively small amount of corn.  HFCS is now a ubiquitous ingredient that permeates our entire modern food supply. Starting in the 1980s, the introduction of HFCS has gradually displaced traditional sweeteners such as natural cane sugar, glucose and honey. According to the USDA, HFCS can cost up to 50% less than cane and other traditional sugars. This cost differential is particularly significant in industries where sweeteners constitute a major portion of production costs such as in soft drinks, artificial fruit juices, sweet baked goods, snack foods and candy, breakfast cereals, condiments and sauces, sweetened dairy products such as yoghurt and ice cream, and a large variety of processed canned and prepared meals. A study published in American Journal of Clinical Nutrition found that HFCS accounts for over 40% increase of caloric sweeteners added to foods and beverages. Having a purview of the distribution of different sugars in the American diet helps to illustrate the dominance of HFCS in the food system. Approximately 45 percent of added sugars in the American diet come from HFCS and an additional 2 percent from pure fructose. Between 35-40 percent of sweeteners derive from sucrose, the common table sugar made from sugarcane and sugar beets -- the latter now being genetically modified. The production process involves crushing the plant material to extract the juice, which is then purified, concentrated, and crystallized to produce table sugar.  Not to be confused with HFCS, corn syrup is largely glucose and represents about 10-15 percent of the nation's sugar intake. It is the most common sugar used in baked goods and candy. Lactose and galactose each account for about 4-5 percent of consumed sugars. However they are typically not added sugars to foods but naturally present in all dairy products.  Finally, honey, which at one time was a common food ingredient, today only accounts for about 1-2 percent of sweeteners.  Moreover, according to FDA testing, a lot of commercial honey found in grocery stores has been adulterated with HFCS and other sweeteners, such sucrose derived from cane and GMO beet sugars and artificial honey-flavored imitators.  A general estimate is that 20-30 percent of honey sold is impure.  Back in the 1970s and 1980s when I frequently railed publicly against the sugar industry and the health risks of processed table sugar that then completely dominated the food industry, I would never have imagined that sucrose would be gradually replaced by HFCS. This replacement accelerated after the emergence of genetically modified (GM) corn. As noted above, the vast majority of HFCS produced in the United States, the world's larger corn producer globally, is derived from genetically modified (GM) corn. Estimates suggest that around 85-90% of the corn grown in the U.S. is genetically modified. Therefore it is reasonable to infer that approximately 85-90% of HFCS is derived from GM corn. As many court cases and exposes of corruption in the agro-chemical industry have cone to light, GM corn has dire implications for the production and consumption of HFCS, especially considering the associated health risks linked to the use of toxic herbicides such as glyphosate. Research has linked glyphosate to various health issues, including cancer. A decade ago, the International Agency for Research on Cancer (IARC) classified glyphosate as a "probable human carcinogen"; today, it is no longer probable but a medical fact. Several studies have detected glyphosate residues in food products containing HFCS. A study published in Environmental Health found glyphosate residues in a variety of food products, highlighting the widespread contamination of the food supply with this herbicide. In addition to glyphosate's carcinogenic potential, the toxin has also been shown to disrupt endocrine function and it has been implicated in gut dysbiosis, an imbalance in the gut microbiome. This disruption can lead to a range of health problems, including inflammatory bowel disease (IBD) and other gastrointestinal disorders. Research published in Current Microbiology indicates that glyphosate exposure can alter the composition of the gut microbiota, leading to adverse health outcomes. HFCS and traditional sugars like table sugar differ significantly in their composition and metabolic effects. Sucrose is a disaccharide composed of equal parts glucose and fructose, while HFCS is a mixture of free glucose and fructose, with the fructose content higher than that in sucrose. This difference in composition affects how the body metabolizes these sugars. Briefly, HFCS poses more serious health risks than sucrose. The free fructose in HFCS is absorbed more rapidly than the bound fructose in sucrose, leading to quicker spikes in blood sugar and insulin levels. In addition, the high fructose content in HFCS places a greater burden on the liver, leading to increased fat production and storage, contributing to fatty liver disease and metabolic disorders. In contrast, the balanced glucose-fructose composition of sucrose is metabolized more evenly, posing lower risks. However, it is crucial to realize that excessive or even moderate consumption of any form of sugar can be detrimental to health. Extensive research has linked the consumption of HFCS to a range of adverse health effects. Key among these is metabolic disorders and cardiovascular diseases. A study published in the Journal of Clinical Endocrinology & Metabolism found that high consumption of HFCS is associated with an increased risk of developing metabolic syndrome, which includes conditions such as obesity, insulin resistance, hypertension, and dyslipidemia. These conditions collectively elevate the risk of heart disease and stroke. HFCS has been directly implicated in America's obesity epidemic due to its high fructose content, which is metabolized differently than glucose. Fructose is primarily processed in the liver, where it can be converted into fat more readily than glucose. This process can lead to increased fat accumulation and insulin resistance, both of which are risk factors for obesity and type 2 diabetes. A study in the American Journal of Clinical Nutrition highlighted that high HFCS consumption is correlated with an increased risk of obesity and diabetes, particularly in children and adolescents. HFCS intake also leads to non-alcoholic fatty liver disease (NAFLD). Unlike glucose, which is metabolized by all cells in the body, fructose is metabolized almost entirely in the liver. High levels of fructose overwhelms the liver's capacity to process it, leading to fat accumulation and liver damage. Research published in Hepatology has shown a strong correlation between HFCS consumption and the progression to more severe liver diseases, such as cirrhosis and liver cancer. Recent evidence reveals that HFCS has detrimental effects on cognitive function and mental health. Studies indicate that fructose impairs insulin signaling in the brain, which is crucial for maintaining cognitive functions. A study in the Journal of Physiology found that high-fructose diets can lead to insulin resistance in the brain, potentially increasing the risk of neurodegenerative diseases like Alzheimer's. Additionally, high sugar diets, including those high in HFCS, have been linked to mood disorders, such as depression and anxiety, as detailed in a review in Nature Reviews Neuroscience. HFCS and other fructose-rich sugars can have profound adverse effects on the gut and digestive system. These sugars are known to disrupt the normal functioning of the gastrointestinal tract, contributing to various digestive disorders and altering the gut microbiome. Fructose, unlike glucose, is not directly absorbed by the body. It requires a specific transporter, GLUT5, to be taken up by the intestinal cells. Fructose interferes with these transporters, leading to malabsorption. Unabsorbed fructose travels to the large intestine, where it undergoes fermentation by gut bacteria. This process produces gases such as hydrogen, carbon dioxide, and methane, which cause bloating, gas, and abdominal pain leading to malabsorption and the intestine's inability to absorb fructose efficiently. The gut microbiome, a complex community of trillions of microorganisms living in the digestive tract, is crucial for maintaining digestive health, immune function, and overall well-being. High intake of fructose negatively affects this delicate balance. Studies have shown that diets high in fructose can lead to an imbalance in the gut microbiota composition. This imbalance is characterized by a decrease in beneficial bacteria such as Bifidobacteria and Lactobacilli and an increase in harmful bacteria like Clostridia and Enterobacteria.  A study published in The American Journal of Clinical Nutrition found that high fructose levels increase intestinal permeability, also known as "leaky gut." This condition allows harmful substances, such as toxins and bacteria, to pass from the gut into the bloodstream, triggering inflammation and contributing to the development of various diseases, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). Inflammatory bowel disease, which includes conditions like Crohn's disease and ulcerative colitis, is exacerbated by promoting inflammation and altering the gut microbiota. A study in the journal Gut reported that reducing fructose intake improved symptoms in individuals with IBS, suggesting a direct link between fructose consumption and IBS symptom severity. Finally we need to also consider the catastrophic effects of HFCS on children. Children are particularly vulnerable to the health risks associated with HFCS due to their higher consumption levels relative to their body weight. According to data from the CDC, the average American child consumes approximately 12-16 teaspoons of added sugars per day, a significant portion of which comes from HFCS. This high intake is largely driven by the consumption of sweetened beverages, snacks, and processed foods that are marketed specifically to children. The high consumption of HFCS among children is a major contributor to the rising rates of childhood obesity and metabolic disorders. Studies have shown that children who consume high levels of sugary beverages and snacks are more likely to develop obesity, insulin resistance, and type 2 diabetes. A study published in Pediatrics found that children who consume sugary drinks daily are at a significantly higher risk of developing obesity compared to those who consume them less frequently. There is also growing concern about the impact of HFCS on children's cognitive development and behavior. High sugar diets have been linked to attention deficit hyperactivity disorder (ADHD) and other behavioral issues in children. A study in the Journal of Attention Disorders found that excessive sugar consumption, including HFCS, exacerbates symptoms of ADHD and impair cognitive functions such as memory and learning. A deeper look at the politics of the sugar industry reveals that huge sums are being doled out by the government to support and subsidize sugar companies. Writing for the Wall Street Journal, health journalist Alexandra Wexler explains that American taxpayers are currently responsible for shelling out $280 million to cover the cost of loans from the USDA which sugar producers are unable to pay back. Given the undeniable evidence demonstrating the toxicity of HFCS and other commercial sugars and their enormous toll on the wellbeing of Americans, why is it that our health agencies and elected officials are not calling for an urgent overhaul of existing policies, which graciously support the domestic sugar industry to poison the population? Where is the outrage over bailing out the purveyors of what is likely the most dangerous staple in the American diet? For our answers we must follow the money-trail.

Have you heard the common belief that eating fruit is bad because of the sugar it naturally contains? I'm diving into the research behind eating fruit and more in this Q&A episode on the Darin Olien show.    I discuss the truth about fruit sugars, their impact on your health, how the fiber and phytochemicals in whole fruits can regulate blood sugar levels, and the research behind consuming whole fruits to lower your risk of obesity, type 2 diabetes, and cardiovascular disease. I also dive into the health benefits of unrefined honey, the importance of high-quality honey, and its metabolic effects compared to other sugars.   Don't forget… You can order now by heading to https://darinolien.com/fatal-conveniences-book or order now on Amazon.   Thank you to our sponsors: Vivo Barefoot: Get 20% off your first Vivobarefoot order with DARIN20 at www.vivobarefoot.com   Find more from Darin: Website: https://darinolien.com/ Instagram: https://www.instagram.com/Darinolien/ Book: https://darinolien.com/fatal-conveniences-book/ Down to Earth: https://darinolien.com/down-to-earth/      Links mentioned:  https://nutritionfacts.org/video/if-fructose-is-bad-what-about-fruit/  Health Benefits of Whole Fruits  Whole Fruits vs Fruit Juice  Benefits of Fruit Fiber Sugar on Cognitive Performance Effects of Honey Honey vs Sucrose  

BUFFALO, NY- June 19, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, “Dietary sucrose determines the regulatory activity of lithium on gene expression and lifespan in Drosophila melanogaster.” The amount of dietary sugars and the administration of lithium both impact the lifespan of the fruit fly Drosophila melanogaster. It is noteworthy that lithium is attributed with insulin-like activity as it stimulates protein kinase B/Akt and suppresses the activity of glycogen synthase kinase-3 (GSK-3). However, its interaction with dietary sugar has largely remained unexplored. In this new study, researchers Katharina Jans, Kai Lüersen, Jakob von Frieling, Thomas Roeder, and Gerald Rimbach from the University of Kiel investigated the effects of lithium supplementation on known lithium-sensitive parameters in fruit flies, such as lifespan, body composition, GSK-3 phosphorylation, and the transcriptome, while varying the dietary sugar concentration. “Based on this proposed overlapping bioactivity of dietary sugar and lithium in the female fruit fly, we decided to investigate the extent of these similarities and whether a joint mechanism lies at their root.” For all these parameters, the researchers observed that the efficacy of lithium was significantly influenced by the sucrose content in the diet. Overall, they found that lithium was most effective in enhancing longevity and altering body composition when added to a low-sucrose diet. Whole-body RNA sequencing revealed a remarkably similar transcriptional response when either increasing dietary sucrose from 1% to 10% or adding 1 mM LiCl to a 1% sucrose diet, characterized by a substantial overlap of nearly 500 differentially expressed genes. “Hence, dietary sugar supply is suggested as a key factor in understanding lithium bioactivity, which could hold relevance for its therapeutic applications.” DOI - https://doi.org/10.18632/aging.205933 Corresponding author - Katharina Jans - jans@foodsci.uni-kiel.de Video short - https://www.youtube.com/watch?v=HaxZU4Gd5Z4 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.205933 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, lithium, longevity, glycogen synthase kinase 3, fruit fly, trace element About Aging (Aging-US): Aging aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Aging is indexed by PubMed/Medline (abbreviated as “Aging (Albany NY)”), PubMed Central, Web of Science: Science Citation Index Expanded (abbreviated as “Aging‐US” and listed in the Cell Biology and Geriatrics & Gerontology categories), Scopus (abbreviated as “Aging” and listed in the Cell Biology and Aging categories), Biological Abstracts, BIOSIS Previews, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

En lo último en salud y fitness edición abril 2024, te traigo una selección de los estudios más interesantes y relevantes de las últimas semanas. Vamos a hacer un recorrido por varios temas que nos ayudarán a entender mejor cómo cuidar tu cuerpo y maximizar tu rendimiento. En este episodio vamos a platicar sobre los efectos del frío en el crecimiento muscular, cómo diferentes tipos de azúcares pueden afectar nuestra salud, la relación entre los probióticos y la obesidad, la importancia de la vitamina D en la prevención de la demencia, y la posible conexión entre el consumo elevado de cobre y la migraña. Atajos del Episodio 01:28 - Efectos del frío después del entrenamiento: ¿Reduce el crecimiento muscular?1 04:48 - Los efectos diferenciados del azúcar en las bebidas y la sensibilidad a la insulina2 09:15 - Probióticos y Sinbióticos: Aliados Contra la Obesidad3 12:22 - Vitamina D y Riesgo de Demencia: Una Relación relevante 15:57 - ¿El Consumo Elevado de Cobre Aumenta el Riesgo de Migraña?5   Referencias: 1.      Piñero, A., Burke, R. & Augustin…, F. Throwing cold water on muscle growth: A systematic review with meta‐analysis of the effects of postexercise cold water immersion on resistance training‐induced …. European Journal of … (2024). 2.      Hieronimus, B., Medici, V., Lee, V., Nunez, M. V. & Sigala…, D. M. Effects of Consuming Beverages Sweetened with Fructose, Glucose, High-Fructose Corn Syrup, Sucrose, or Aspartame on OGTT-Derived Indices of Insulin …. Nutrients (2024). 3.      Saadati, S., Naseri, K., Asbaghi, O. & Yousefi…, M. Beneficial effects of the probiotics and synbiotics supplementation on anthropometric indices and body composition in adults: A systematic review and meta‐analysis. Obesity … (2024). 4.      Chen, L. J., Sha, S., Stocker, H. & Brenner…, H. The associations of serum vitamin D status and vitamin D supplements use with all-cause dementia, Alzheimer's disease, and vascular dementia: a UK …. The American Journal of … (2024). 5.      Sun, Y. et al. Association Between Copper Intake and Migraine: a National Cross-sectional Study. Biological Trace Element … (2023).

Dr. Artemis Simopoulos is a physician and researcher specializing in endocrinology, nutrition, and metabolic health. They discuss: traditional hunter-gatherer diets vs. modern Western diets; dietary fats; omega-6 and omega-3 polyunsaturated fats; sucrose & sugar; chronic inflammatory diseases, obesity & diabetes; vegetable & seed oils vs. other cooking oils; processed foods; fish oil supplements; and more.Download a free digital copy of her book: https://www.mdpi.com/books/mono/5908-the-healthiest-diet-for-you-scientific-aspectsMore content on the science of diet & metabolic health: https://substack.com/search/diet%20metabolism?focusedPublicationId=513528&searching=focused_postsSupport the showSign up for the free weekly Mind & Matter newsletter:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Become a Premium Subscriber to access full content library, including full premium episodes:[https://mindandmatter.substack.com/subscribe?utm_source=menu&simple=true&next=https%3A%2F%2Fmindandmatter.substack.com%2F]Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for $50 off:[https://www.lumen.me/shop?fid=8731&utm_source=influencer&utm_medium=influencer&discount=MIND]

Sugar is the Devil.  In the 80's and 90's we were told it was dietary fat, but now we know differently. Sugar is one of the most addictive substances on earth.  So how do you break up with it?Go on, admit it, you need to break up with sugar. Cam and Amelia have had love affairs with sugar, so you aren't alone. In this episode, we talk about all kinds of sugar and how to recognize them. I know breaking up with sugar feels like losing your best friend, but you can do it! 02:23 Spouse, gummy worms, sugar addiction, bad.05:09 No longer need you. Forget you.08:12 Past life teaching 1st grade, moon+sugar=amped kids, stress control.11:45 Make your own granola with healthy ingredients.12:35 Stomachache from sugary organic Clif builder bar.17:00 "Journey similar to yours, learning about healthy food."19:24 Sugar leads to aging and disease.23:34 Starting CrossFit, earned ice cream. Changed habits during chaotic life.26:02 Approach same, evaluate, possibly discard, occasionally indulge.29:06 Love it. Right, sweetness from friends. Good convo. Enjoy holidays on/off plate.Other Names for Sugar:Sucrose: Common table sugar derived from sugar cane or sugar beets.Fructose: Naturally occurring sugar found in fruits and honey.Glucose: Simple sugar that serves as a primary source of energy for the body.Lactose: Sugar present in milk and dairy products.Maltose: Sugar produced during the digestion of starch, found in malted foods.Dextrose: Another name for glucose, often used in food and medical applications.High Fructose Corn Syrup (HFCS): Sweetener made from corn starch, commonly used in processed foods and beverages.Agave Nectar/Syrup: Sweetener derived from the agave plant, often used as a natural alternative to sugar.Honey: Natural sweet substance produced by bees.Maple Syrup: Sweet syrup made from the sap of sugar maple trees.Brown Sugar: White sugar mixed with molasses, giving it a brown color and distinct flavor.Powdered/Confectioner's Sugar: Finely ground sugar mixed with cornstarch, used in baking and confectionery.Turbinado Sugar: Raw sugar with a larger grain size and a molasses flavor.Coconut Sugar: Sugar derived from the sap of the coconut palm tree.Date Sugar: Sweetener made from dried, ground dates.Barley Malt Syrup: Sweetener made from malted barley, often used in brewing and baking.Rice Syrup: Sweetener derived from brown rice.Blackstrap Molasses: Dark, viscous byproduct of sugar refining, rich in minerals.Cane Juice: Juice extracted from sugar cane before refining.Invert Sugar: Mixture of glucose and fructose formed by breaking down sucrose.Stay Connected!Amelia Website: https://www.thehelpfulplate.com/ IG: https://www.instagram.com/thehelpfulplate/ Cam Website: https://www.camoyler.com/ IG: https://www.instagram.com/heymomma_cam/ TikTok: https://www.tiktok.com/@heymomma_cam Midlife Mommas IG: https://www.instagram.com/midlife.mommas/ Please share, rate, and review the podcast. We appreciate you! ❤️

Is there such a thing as a quick fix? Neil deGrasse Tyson, Chuck Nice, and Gary O'Reilly learn about the science behind a wave of new weight loss drugs, the ethics of Ozempic use, and off-label prescriptions with exercise scientist, Dr. Nick Tiller.For more information on the new book: https://startalkmedia.com/books/NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/miracle-drugs-quick-fixes-with-dr-nick-tiller/Thanks to our Patrons Christian Attwood, Tyler Loveland, Ruhan Periyacheri, Jeff Parker, Ed Thorton, and Dakota Ponder for supporting us this week.Photo Credit: HualinXMN, CC BY-SA 4.0, via Wikimedia Commons

Contributor Andy Carter chats with Marshall about the differences between using sucrose, aka table sugar, and dextrose in the production of hard seltzer.  The Brülosophy Podcast is brought to you by Imperial Yeast who provide brewers with the most viable and fresh yeast on the market. Learn more about what Imperial Yeast has to offer at ImperialYeast.com today. | Relevant Article | Sucrose vs. Dextrose In Hard Seltzer xBmt

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.20.549769v1?rss=1 Authors: Wilkinson, C. S., Blount, H. L., Davis, S., Rojas, G., Wu, L., Murphy, N. P., Schwendt, M., Knackstedt, L. A. Abstract: Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we assessed whether co-consumption of oxycodone and alcohol would influence intake of one another, demand for oxycodone, and the neurocircuitry underlying cue-primed reinstatement of oxycodone-seeking. Male and female rats underwent oxycodone intravenous self-administration (IVSA) with access to either alcohol (20% v/v) and water or only water immediately after the IVSA session. Next, economic demand for intravenous oxycodone was assessed while access to alcohol and/or water continued. Control rats self-administered sucrose followed by access to alcohol and/or water. Rats underwent extinction training and brains were processed for c-fos mRNA expression immediately following a cue-primed reinstatement test. While both sexes decreased oxycodone intake if they had access to alcohol, and decreased alcohol intake if they had access to oxycodone, female oxycodone+alcohol rats exhibited decreased demand elasticity for intravenous oxycodone and increased cue-primed reinstatement while male rats did not. Spontaneous withdrawal signs were correlated with oxycodone intake while alcohol intake was correlated with anxiety-like behavior. Alcohol consumption increased the number of basolateral and central amygdala neurons activated during sucrose and oxycodone reinstatement and the number of ventral and dorsal striatum neurons engaged by sucrose reinstatement. Nucleus accumbens shell dopamine 1 receptor containing neurons displayed activation patterns consistent with oxycodone reinstatement. Thus, alcohol alters the motivation to seek oxycodone in a sex-dependent manner and alters the neural circuitry engaged by cue-primed reinstatement of sucrose and oxycodone-seeking. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Listen to Dr. Tom Roselle, DC discuss the different types of sugar and how they affect your body. The effects of added sugar intake are higher blood pressure, inflammation, weight gain, diabetes, and fatty liver disease which are all linked to an increased risk for heart attack and stroke. Too much added sugar can be one of the greatest threats to cardiovascular disease. The four most common forms of sugars. •    Glucose (a.k.a. carbohydrates in food and drinks) •    Fructose (a.k.a. fruit sugar) •    Sucrose (a.k.a. table sugar) •    Lactose (a.k.a. dairy sugar) For this and more episodes of Ageless Health® with Dr. Tom Roselle, DC, please visit https://www.drtomroselle.com/ageless-health-podcast/

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.06.30.547267v1?rss=1 Authors: Zamal, M. Y., Venkataramana, C., Subramanyam, R. Abstract: In the phototrophic alphaproteobacteria, photosynthesis is performed by pigment-protein complexes, including the light-harvesting complexes known as LH1 and LH2. The photosystem also encompasses carotenoids to assist in well-functioning of photosynthesis. Most photosynthetic bacteria are exposed to various abiotic stresses, and here, the Rhodobacter (R.) alkalitolerans were extracted from the alkaline pond. We report the comparative study of photosynthetic apparatus of R. alkalitolerans in various light intensities in relation to this bacterium's high pH tolerance ability. We found that as the light intensity increased, the stability of photosystem complexes decreased in normal pH (npH pH 6.8{+/-}0.05) conditions, whereas in high pH (hpH pH 8.6{+/-}0.05) acclimation was observed. The content of bacteriochlorophyll a, absorbance spectra, and circular dichroism data shows that the integrity of photosystem complexes is less affected in hpH compared to npH conditions. Sucrose density and LP-BN of photosystem complexes also shows that LH2 is more affected in npH than hpH, whereas RC-LH1 monomer or dimer has shown interplay between monomer and dimer in hpH although the dimer and monomer both increased in npH. Additionally, the phosphatidylcholine (PC) levels have increased in hpH conditions. Moreover, qPCR data showed that the subunit -c of ATPase levels was overexpressed in hpH. Consequently, the P515 measurement shows that more ATP production is required in hpH, which dissipates the protons from the chromatophore lumen. This could be the reason the photosystem protein complex destabilized due to more lumen acidification. To maintain homeostasis in hpH, the antiporter NhaD expressed more than in the npH condition. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

These four common types of sugar interact with your body differently, but it's best to minimize all of them for optimal metabolic health. Author: Ajai Raj Reviewer: Dr. Ami Kapadia Link to article: https://www.levelshealth.com/blog/whats-the-difference-between-glucose-fructose-sucrose-and-lactose Become a Levels Member – ⁠https://levels.link/insights⁠ Learn about Metabolic Health – ⁠levelshealth.com/blog⁠ Follow Levels on Social – @Levels on ⁠Instagram⁠ and ⁠Twitter

Microbes have existed on Earth for almost 4 billion years; 3x as long as multicellular organisms and 1000x longer than humans. So what does the future hold? Will recent advances in genetic engineering enable us to create bacterial ‘drug-delivery' machines or self-replicating microbial vaccines? What will the first human-created lifeform mean for our understanding of biology? Will humanity end with a ‘microbial bang', or might microbes perhaps be the solution we need to spread our wings beyond this planet?A lecture by Robin May recorded on 10 May 2023 at Barnard's Inn Hall, London.The transcript and downloadable versions of the lecture are available from the Gresham College website: https://www.gresham.ac.uk/watch-now/microbial-futureGresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham's mission, please consider making a donation: https://gresham.ac.uk/support/Website:  https://gresham.ac.ukTwitter:  https://twitter.com/greshamcollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollegeSupport the show

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.21.537763v1?rss=1 Authors: Deseyve, C., Domingues, A. V., Carvalho, T. T. A., Vieitas-Gaspar, N., Pinto, L., Sousa, N., Coimbra, B., Rodrigues, A. J., Soares-Cunha, C. Abstract: To survive, individuals must learn to associate cues in the environment with emotionally relevant outcomes. This association is partially mediated by the nucleus accumbens (NAc), a key brain region of the reward circuit that is mainly composed by GABAergic medium spiny neurons (MSNs), that express either dopamine receptor D1 or D2. Recent studies showed that both populations can drive reward and aversion, however, the activity of these neurons during appetitive and aversive Pavlovian conditioning remains to be determined. Here, we investigated the relevance of D1- and D2-neurons in Pavlovian associations, by measuring calcium transients with fiber photometry during appetitive and aversive Pavlovian tasks. Sucrose was used as a positive unconditioned stimulus (US) and foot shock was used as a negative US. We show that during appetitive Pavlovian conditioning, D1- and D2-neurons exhibit a general decrease in activity in response to CS and to US across learning, with dynamic, and partially overlapping, activity responses to CS and US. During the aversive Pavlovian conditioning, D1- and D2-neurons showed an increase in the activity in response to the CS and to the US (shock). Our data supports a synchronous role for D1- and D2-neurons in appetitive and aversion processing. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This week we're tackling three big ideas about sugar: It causes hyperactivity in kids, it's as addictive as cocaine and it raises blood sugar in universal, predictably spiky ways.  Thanks to David Johnston for helping us with sources for this week's episode!Support us:Hear bonus episodes on PatreonDonate on PayPalGet Maintenance Phase T-shirts, stickers and moreBuy Aubrey's bookListen to Mike's other podcastLinks!Fat Talk: Parenting in the Age of Diet Culture by Virginia Sole SmithSugar Rush: Science, Politics and the Demonisation of Fatness by Karen ThrosbyIs sugar really as addictive as cocaine? Scientists row over effect on body and brainSugar Is Not the EnemyDr. Benjamin F. Feingold, Controversial PediatricianIs There Such a Thing as a ‘Sugar High'?Effects of Diets High in Sucrose or Aspartame on The Behavior and Cognitive Performance of ChildrenSugar and the Hyperactive ChildSome popular diets are based on this carb-rating scale. Here's why it could be misleading.Glycemic Index: History and Clinical ApplicationGlycemic Index and Glycemic Load Low glycaemic index or low glycaemic load diets for overweight and obesityWhat is the glycaemic indexDon't Play a Numbers Game, Experts Say, Just Eat Your VegetablesSugar addiction: the state of the scienceThanks to Doctor Dreamchip for our lovely theme song!Support the show

Tämä jakso on tehty yhteistyössä Float Kallion / Roban (https://wefloat.fi/) ja Oura-älysormuksen (https://ouraring.com/partners/Lepopaiva/) kanssa.Tässä jaksossa:- Vastasimme kuuntelijan kysymykseen crossfitin ja animal based -ruokavalion yhteensopivuudesta, onko merkitystä saako hiilarit pastasta vai hedelmistä- Akiksen polven kuntoutus etenee- Jaskan carnivore / lion diet -päivitys, hommat rokkaa!- Oppia omaan elämään kolme vuotiaan loppumattomista miksi-kysymyksistäLinkit:- Why Fructose and Sucrose are Beneficial for Athletes https://www.nutritiontactics.com/why-fructose-is-beneficial-for-athletes/- Jaakko Dahlbacka Avarassa luonnossa https://www.youtube.com/watch?v=ki03aVj13g0- Luo ruokavalio tekoälyn avulla https://www.youtube.com/watch?v=9j73xEOXYas

In today's episode, Paul chats with Bioenergetic Health researcher, Georgi Dinkov. They jump down the rabbit hole on a myriad of topics, including the distinction between table sugar and high-fructose corn syrup, how starch damages the gut, polyunsaturated fatty acids, sunlight, emfs and more. Sit back, relax and put on your open-minded thinking cap–you might learn a thing or two. 00:11:05 Sucrose vs. high fructose corn syrup 00:26:35 The link between food, stress hormones, and mental disorders 00:35:35 Thoughts on ketogenic diets 00:43:50 Should we limit our carb intake? 00:52:13 How to test cortisol and other hormones 00:56:30 How hormones and genetics play a role in metabolizing sugar 1:00:02 The Randle Cycle 1:08:08 Low fat vs. high fat diets 01:16:05 Exhaustive exercise 01:27:28 A deep dive into serotonin & SSRIs 01:48:40 Why to avoid starchy foods 01:51:25 The importance of organs 02:06:55 Where to find Georgi's content *Salaryman Documentary * Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order or Carnivore5 for 5% off subsequent orders Our Sponsor LetsGetChecked: 20% off your order at www.TRYLGC.com/paulsaladino for 25% off Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt Marek Health: marekhealth.com/fundamentalhealth, use code PAUL for 10% off your first lab order

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.14.520457v1?rss=1 Authors: Hoffman, J. L., Faccidomo, S., Taylor, S. M., DeMiceli, K. G., May, A. M., Smith, E. N., Whindleton, C. M., Hodge, C. W. Abstract: Rationale: The development and progression of alcohol use disorder (AUD) is widely viewed as maladaptive neuroplasticity. The transmembrane alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) regulatory protein 8 (TARP {gamma}-8) is a molecular mechanism of neuroplasticity that has not been evaluated in AUD or other addictions. Objective: To address this gap in knowledge, we evaluated the mechanistic role of TARP {gamma}-8 bound AMPAR activity in the basolateral amygdala (BLA) and ventral CA3 hippocampus (vHPC) in the positive reinforcing effects of alcohol, which drive repetitive alcohol use throughout the course of AUD, in C57BL/6J mice. These brain regions were selected because they exhibit high levels of TARP {gamma}-8 expression and send glutamate projections to the nucleus accumbens (NAc), which is a key nucleus in the brain reward pathway. Methods and Results: Site-specific pharmacological inhibition of AMPARs bound to TARP {gamma}-8 in the BLA via bilateral infusion of the selective negative modulator JNJ-55511118 significantly decreased operant alcohol self-administration with no effect on sucrose self-administration in behavior-matched controls. Temporal analysis showed that reduction of alcohol-reinforced responding occurred greater than 25 min after the onset of responding, consistent with a blunting of the positive reinforcing effects of alcohol in the absence of nonspecific behavioral effects. In contrast, inhibition of TARP {gamma}-8 bound AMPARs in the vHPC selectively decreased sucrose self-administration with no effect on alcohol. Conclusions: This study reveals a novel brain region-specific role of TARP {gamma}-8 bound AMPARs as a molecular mechanism of the positive reinforcing effects of alcohol and non-drug rewards. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.30.518425v1?rss=1 Authors: Verharen, J. P. H., de Jong, J. W., Zhu, Y., Lammel, S. Abstract: The sucrose preference test (SPT) measures the relative preference of a sucrose solution over water to assess hedonic behaviors in rodents. The SPT involves numerous complex behaviors, including learning, motivation, and choice. Yet, it remains uncertain whether its main outcome measure, sucrose preference, can reflect these behavioral subcomponents. Here, we conducted an experimental and computational decomposition of mouse behavior in the SPT and discovered previously unrecognized behavioral subcomponents associated with changes in sucrose preference. While both acute and chronic stress reduced sucrose preference, only chronic stress evoked anhedonia. Additionally, reduced sucrose preference induced by optogenetics is not always indicative of anhedonia but can also reflect learning deficits. Even small variations in experimental conditions influence behavior, task outcome and interpretation. Thus, an ostensibly simple behavioral task can entail high levels of complexity, demonstrating the need for careful dissection of behavior into its subcomponents when studying the underlying neurobiology. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Drs. Raja and Shah discuss the link between sugar and hyperactivity in children. Since many will still have some Halloween candy leftover AND as we are heading into Thanksgiving and the holidays, we thought it would be an interesting topic to delve into. Effects of Diets High in Sucrose or Aspartame on The Behavior and Cognitive Performance of Children Meta-analysis: The Effect of Sugar on Behavior or Cognition in Children Effects of sugar injection expectancies on mother-child interactions

In this episode, we're eating all the candy! Luckily this episode comes out on Halloween, so Happy Halloween everyone! Anyway, new sweets are invading Juban, and Minako is absolutely addicted. But once she starts to put on weight, she decides to quit Satan's Sucrose and give up sugar. The influx of sweets in the city is being monitored by the Dark Agency, and the Monster of the Week decides to harness energy from people wanting to shed their dessert weight! Will Minako be able to quit exercising in time to undo the latest plot by the enemy? Listen on to find out! *** Justin's Twitter & Instagram: @justingrey22 Marcella's Instagram: @blogginginpyjamas Podcast Twitter & Instagram: @sailormangapod Podcast Email: sailormangapodcast@gmail.com --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Today's episode was inspired by my own journey with a potential sucrose intolerance.  This episode goes into what it is, symptoms, how to diagnose it, causes, treatment options and more!References:https://iffgd.org/gi-disorders/congenital-sucrase-isomaltase-deficiency-csid/https://medlineplus.gov/genetics/gene/si/https://foodinsight.org/what-is-sucrose/https://theceliacmd.com/the-sucrose-intolerance-diet/**NEWS ALERT!!!** - My holistic wellness practice is officially open!  If you have been interested in working with me to heal your gut, I strongly encourage you to reach out to me via  social media or via my new website by clicking HERE to learn more, and to schedule a complimentary call.Products I am OBSESSED with:Therasage:Use code KELLYB to save 10% on your own portable Infrared Sauna and take your healing to the next level!  Click HERE to shop.Funk It Wellness:Funk It Wellness Seed Cycling Kits and Maca Powder can be found at: https://funkitwellness.com/Use the code: KELLY20 to save 20% on your order!!Skin Essence Organics:Skin Essence Organics is an amazing company makes affordable, non-toxic skin care products that not only smell good, but feel good, too!  All of their products are 100% plant-based, organic, cruelty-free, gluten-free, and non-GMO.  To start supporting your body and our environment, head on over to https://www.skinessenceorganics.com/ (if you are in the US) or https://www.skinessence.ca/ (if you are in Canada) to try out these amazing products.   You can get 15% off of your order when you use the code: kelly15, plus free shipping on orders of $49 or more.Wolven Threads:Wolven is a clothing company with a mission to promote sustainability, diversity, body positivity, and creative/artistic appreciation.  Their clothing is super comfy and incredibly unique.  Their clothing is made from BPA free plastic bottles, which is so cool!  The packaging is also sustainable in that everything is either reusable or biodegradable (like the paper box it comes in).  If you know me, you know I am a huge advocate for eco-friendly products.  Not only do they help us live better lives, but the planet is massively impacted by doing so.  If you are interested in checking them out, make sure to use my code: KELLYB20  at Wolven Threads for a discount on each of your orders.  I can't wait for you to check them out and let me know what you think!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.03.509933v1?rss=1 Authors: Smiley, C. E., Pate, B. S., Bouknight, S. J., Francis, M. J., Nowicki, A. V., Harrington, E. N., Wood, S. K. Abstract: While over 95% of the population has reported experiencing extreme stress or trauma, females of reproductive age develop stress-induced neuropsychiatric disorders at twice the rate of males. This suggests that ovarian hormones may facilitate neural processes that increase stress susceptibility and underlie the heightened rates of these disorders, like depression and anxiety, that result from stress exposure in females. However, there is contradicting evidence in the literature regarding estrogen's role in stress-related behavioral outcomes. Estrogen signaling through estrogen receptor beta (ERb) has been traditionally thought of as anxiolytic, but recent studies suggest estrogen exhibits distinct effects in the context of stress. Furthermore, ERb is found abundantly in many stress-sensitive brain loci, including the central amygdala (CeA), in which transcription of the vital stress hormone, corticotropin releasing factor (CRF), can be regulated by an estrogen response element. Therefore, these experiments sought to identify the role of CeA ERb activity during stress on behavioral outcomes in naturally cycling, adult, female Sprague-Dawley rats. Rats were exposed to an ethological model of vicarious social stress, witness stress (WS), in which they experienced the sensory and psychological aspects of an aggressive social defeat encounter between two males. Following stress, rats exhibited stress-induced anxiety-like behaviors in the marble burying task, and, finally, brain analysis revealed increased ERb and CRF specifically within the CeA following exposure to stress cues. Subsequent experiments were designed to target this receptor in the CeA using microinjections of the ERb antagonist, PHTPP, prior to each stress session. Sucrose preference, acoustic startle, and marble burying tasks determined that blocking ERb in the CeA during WS prevented the development of depressive-,anxiety-like, and hypervigilant behaviors. Additionally, brain analysis revealed a long-term decrease of intra-CeA CRF expression in PHTPP-treated rats. These experiments indicate that ERb signaling in the CeA, through its effects on CRF, contributes to the development of negative valence behaviors that result from exposure to repeated social stress in female rats. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

Valeria Rodriguez is a voice actor, musician and dungeon master.   They are best known for voicing Sucrose in Genshin Impact, Strawberry Crape Cookie in Cookie Run Kingdom and Lagoon Blue in the new Monster High reboot.   In this episode Valeria and I talk about their career, Genshin Impact, Cookie Run Kingdom, money management, Monster High, negative fan backlash, our favorite video games from the past two decades, social media, Dungeons & Dragons and werewolf movies.   Valeria's social media profiles: https://twitter.com/elvisbadger https://www.twitch.tv/ValeriaTheWerewolf https://www.instagram.com/valeriarodriguezvo/ https://www.youtube.com/ValeriaTheWolf    

In Episode #222, I'm joined by Drew Harrisberg and Kieron Rooney, PhD to discuss how the biochemistry of exercise can impact your health. We cover a wide range of topics, including mitochondria efficiency, metabolic flexibility, and fat adaptation. Dr Rooney also offers training advice, and his thoughts on a ketogenic diet. Evidence continuously shows us that the multitude of factors contributing to health and longevity are incredibly complex. Today, Kieran Rooney, PhD sits down with Drew Harrisberg and me to break down the biochemistry behind exercise, exploring both the theory and practical applications of improving your fitness. Specifically, we cover: Intro [0:00] Rodent Studies on Sucrose [5:40] Biochemistry of Exercise [22:28] Creatine Supplementation for Athletes [37:19] Do you need meat for creatine? [42:40] How Our Bodies Produce ATP [44:41] Defining Mitochondria [58:43] Increasing Efficiency [1:03:56] Omega 6s: Essential or Problematic? [1:06:00] Metabolic Flexibility [1:15:20] Make more Mitochondria [1:18:08] Mitochondria & Longevity [1:29:00] Lactate Levels [1:35:14] Best Training Advice [1:50:16] HIIT vs Endurance [2:01:10] Can Keto Work Long-Term? [2:12:42] Outro [2:45:15] To connect with Drew Harrisberg, you can find him on Instagram and visit his website, Drew's Daily Dose. Kieron Rooney, PhD is active on Twitter, and you can learn more about him and his work here. The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. Enjoy, friends. Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and high protein plant performance recipe book Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Dr. Ken Sikaris talks about the differing effects of glucose, fructose, and sucrose in the body. Mentioned in this episode: Lipedema & Lymphedema Heart to Heart: A Collaborative 3-Day Learning Event Join us for three days full of immersive learning and discover cutting-edge holistic strategies that would help to drastically improve your health... and your quality of life. https://lipedema.captivate.fm/heart2heart (Join our Event!)

Contributor: Jarod Scott, MD Educational Pearls: Rectal prolapse is an evagination of the rectal tissue through the anal opening Factors that weaken the pelvic floor muscles increase the risk of rectal prolapse These include age > 40, female, multiple pregnancies, constipation, diarrhea, cystic fibrosis, prior pelvic floor surgeries, or other pelvic floor abnormalities Noninvasive treatment options include increasing fluid and fiber intake to soften stools as well as using padding/taping to reinforce the perineum Surgery is an option to repair the prolapse so long as the patient is a good surgical candidate Medical sugar can be used as a desiccant to dry out and shrink the prolapse thus allowing for easier manual replacement References Coburn WM, 3rd, Russell MA, Hofstetter WL. Sucrose as an aid to manual reduction of incarcerated rectal prolapse. Ann Emerg Med. 1997;30(3):347-349. 2Gachabayov M, Bendl R, Flusberg M, et al. Rectal prolapse and pelvic descent. Curr Probl Surg. 2021;58(9):100952. Segal J, McKeown DG, Tavarez MM. Rectal Prolapse. In: StatPearls. Treasure Island (FL): StatPearls Publishing. Copyright © 2022, StatPearls Publishing LLC.; 202   Summarized by Mark O'Brien, MS4 | Edited by John Spartz MS4 & Erik Verzemnieks, MD   The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.  Donate to EMM today!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/fructose 2:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 3:00 - AVALONX SERRAPEPTASE: Get Melanie's Serrapeptase Supplement: A Proteolytic Enzyme Which May Help Clear Sinuses And Brain Fog, Reduce Allergies, Support A Healthy Inflammatory State, Enhance Wound Healing, Break Down Fatty Deposits And Amyloid Plaque, Supercharge Your Fast, And More!  AvalonX Supplements Are Free Of Toxic Fillers And Common Allergens (Including Wheat, Rice, Gluten, Dairy, Shellfish, Nuts, Soy, Eggs, And Yeast), Tested To Be Free Of Heavy Metals And Mold, And Triple Tested For Purity And Potency. Order At AvalonX.us, And Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At melanieavalon.com/avalonx 5:10 - FOOD SENSE GUIDE: Get Melanie's App At Melanieavalon.com/foodsenseguide To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More!  6:00 - BEAUTYCOUNTER: Non-Toxic Beauty Products Tested For Heavy Metals, Which Support Skin Health And Look Amazing! Shop At beautycounter.com/melanieavalon For Something Magical! For Exclusive Offers And Discounts, And More On The Science Of Skincare, Get On Melanie's Private Beautycounter Email List At melanieavalon.com/cleanbeauty! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz 10:50 - Beginning Of Fructose Research 14:30 - How Sugar Can Cause Weigh Gain Independently Of Caloric Intake 17:30 - Leptin Resistance 19:20 - BEAUTY AND THE BROTH: Support Your Health With Delicious USDA Organic Beauty & The Broth Bone Broth! It's Shelf Stable With No Preservatives, And No Salt Added. Choose Grass Fed, Grass Finished Beef, Or Free Range, Antibiotic And Hormone-Free Chicken, Or Their NEW Organic Vegan Mushroom Broth Concentrate Shipped Straight To Your Door! The Concentrated Packets Are 8x Stronger Than Any Cup Of Broth: Simply Reconstitute With 8 Ounces Of Hot Water. They're Convenient To Take Anywhere On The Go, Especially Travel! Go To Melanieavalon.Com/Broth To Get 15% Off Any Order With The Code MelanieAvalon! 23:10 - Defining Glucose, Sucrose, And Fructose 26:55 - "Tasteless" Mice 28:00 - Craving Sugar  31:20 - 5 Great Tastes 33:00 - Artificial Sweeteners 34:00 - Blocking The Fructokinase In The Liver 36:00 - How Fructose Tricks The Body 42:10 - How Fructose Uses Glucose To Create Fat 50:00 - Polyol Pathway 51:40 - Stress & Dehydration 53:50 - Salt 57:00 - NUTRISENSE: Get Your Own Personal Continuous Glucose Monitor (CGM) To See How Your Blood Sugar Responds 24/7 To Your Food, Fasting, And Exercise! The Nutrisense CGM Program Helps You Interpret The Data And Take Charge Of Your Metabolic Health! Learn More About Nutrisense In Melanie's Interview With Founder Kara Collier At melanieavalon.com/nutrisense. Get $40 Off A CGM At nutrisense.io/melanie With The Code MelanieAvalon 1:00:30 - How Hibernation Mimics Metabolic Syndrome 1:04:30 - Evolutionarily, Where Did This Start? 1:07:45 - The Natural Fasting Cycle 1:08:30 - The Role Of Fructose In The Cells, AMPK, And AMPD 1:16:00 - What Happens When You Combine Starvation With The AMPK Pathway? 1:21:00 - Starvation Mode 1:24:30 - What About Whole Fruit? The Role Of Vitamin C

Sucrose and High Fructose Corn Syrup ruled my pantry, fridge and freezer back in my unhealthy days. Defining them, categorizing them and knowing how the body metabolizes them made all the difference in the world in reclaiming my health. I will introduce them here and may this information do for you what it did for me.

What's crackalackin Mob?! shiiiit nothing here except Matt has been in Costa Rica and the Dominican Republic for weeks now (will he come back?) and Josh has bought a house and is in the middle of a shit show called moving with a toddler. So therefore, enjoy this double feature all about sugar and we will be back next week with brand new shows. Including another Headlines and Macabre Reality the Gameshow! See you soon Mobsters!  Woot woot! Get out your sweetest two toofs, because we have another delicious double episode made completely of sugar. How many times does Matt start over trying to say "prevent potential contamination"? Try it, it's no easy feat. Is he the new Hamilton? Just how big was that molasses wave brah? Find out now! And remember if you wanna pick up a waitress/waiter just throw a packet of sugar on the floor and tell them you found their nametag! Hey Sugar! Today we have for you A Little Sucrose for Comfort which includes: Imperial Sugar Refinery Explosion and Boston Molassacre.  If you like what you hear please tell someone and rate us it does help! Everything is done by the 2 of us, we have no big wigs backing us, the man doesn't have a hand in this baby! so we need YOU!  Stay safe out there and be careful not to find yourself in your own Macabre Reality. Find us on all socials @macabrepod1 and email us at macabrepod1@gmail.com

This is Part II of an extensive audio essay on the history and mechanics of the Margarita cocktail. In Part I, we examined the origins of sour taste perception and tracked a number of the Margarita's precursors, including grog, the Crusta, and the Daisy. In this installment, we explore sugar, the Margarita's chief technology, and trace it through a number of formula changes to understand how this cocktail hacks our innate biology and psychology. To get to the heart of how the Margarita works, we need to start asking questions like: Where does a traditional “sour” stop and a margarita begin? Is the salted rim optional, essential, or something else entirely? And Should we think of this as a cocktail to be served “up,” “on the rocks,” or does it not really matter? All of this might seem to boil down to a simple question of definitions, but in fact, if you follow the evolution of the Margarita and its ingredients and proportions over time, you begin to realize that the look and feel of a Margarita is a wonderful core sample of the culture and values of any given time and place.

References Infect Immun. 2018 Jul; 86(7): e00035-18 J Biol Chem. 2019 Jun 7;294(23):9213-9224 Egyptian Journal of Basic and Applied Sciences. 2018. (5) 4 : 237-244 Arteriosclerosis, Thrombosis, and Vascular Biology. 2019. (39) 3: 432-445 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

ROVECTIN Skincare Clean Forever Young Biome AmpouleAt Yesstyle: https://ys.style/jeeXKUxLzmbUse Rewards Code NOBSBEAUTY for an additional discount!Rovectin Skincare Clean Forever Young Biome Ampoule Full Ingredients List:Water, Lactobacillus Ferment, Propanediol, Butylene Glycol, Glycerin, Glycereth-26, Niacinamide, 1,2-Hexanediol, Lactobacillus/Soybean Ferment Extract, Bifida Ferment Lysate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Anastatica Hierochuntica Extract, Solanum Melongena (Eggplant) Fruit Extract, Xylose, Sucrose, Panthenol, Adenosine, Biosaccharide Gum-1, Tromethamine, Hydrogenated Lecithin, Sodium Phytate, Tocopherol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polyglyceryl-10 Laurate, Diphenyl Dimethicone, Triethylhexanoin, Ethylhexylglycerin, Fructooligosaccharides, Xanthan Gum, Carbomer, Citric Acid, Sodium Citrate, Disodium EDTA*******Podcast LinksApple - https://b.link/No_BS_Apple_PodcastGoogle - https://b.link/No_BS_Google_PodcastAmazon - https://b.link/No_BS_Amazon_PodcastSpotify - https://b.link/No_BS_Spotify_PodcastStitcher - https://b.link/No_BS_Stitcher_PodcastRSS - https://feeds.redcircle.com/671dd1b2-a989-41d5-94d5-30c014e06149********Sephora - https://fxo.co/1231867/sephoraUlta - https://fxo.co/1231867/ultaAmazon - https://www.amazon.com/shop/nobsbeautyYes Style - https://ys.style/kk2Vjrv798Style Korean - http://www.stylekorean.com/?af_id2=nobsbeautyThese are affiliate links if you purchase anything from one of these stores using this link No BS Beauty will make a small commission on what you buy.********I am proud to offer my very own beauty products at Amazon. We are starting small but hope to grow these offerings. Take a look and if you can pick one or two up, it helps keep this channel truly independent.My Products:No BS Beauty Travel Set - https://amzn.to/2PgPzFZNo BS Beauty Airless Jars - https://bit.ly/2Ev6X6N or https://amzn.to/2RCEq4sNo BS Beauty Color Switcher - https://amzn.to/2RCEAJ6See my own page on Amazon - https://www.amazon.com/shop/nobsbeautywww.noBSbeauty.net*******My Patreon - https://www.patreon.com/noBSbeauty*******PayPal Tip Jar - https://bit.ly/donate_NBSBIf you want to leave a tip ... Thanks! 

Radio Ligevægt udbringer en nytårsskål i tonicsodavand og lytterne får en afklaring på om man bliver tyk af at drikke sodavand. Konklusioner og analyser er baseret på disse videnskabelige artikler:Malik VS, Pan A, Willett WC, Hu FB. Sugar-sweetened beverages and weight gain in children and adults: a systematic review and meta-analysis. Am J Clin Nutr. 2013 Oct;98(4):1084-102. doi: 10.3945/ajcn.113.058362. Epub 2013 Aug 21. PMID: 23966427; PMCID: PMC3778861.Trumbo PR, Rivers CR. Systematic review of the evidence for an association between sugar-sweetened beverage consumption and risk of obesity. Nutr Rev. 2014 Sep;72(9):566-74. doi: 10.1111/nure.12128. Epub 2014 Aug 4. PMID: 25091794.Ebbeling CB, Feldman HA, Steltz SK, Quinn NL, Robinson LM, Ludwig DS. Effects of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors, Body Composition, and Sweet Taste Preference: A Randomized Controlled Trial. J Am Heart Assoc. 2020 Aug 4;9(15):e015668. doi: 10.1161/JAHA.119.015668. Epub 2020 Jul 22. PMID: 32696704; PMCID: PMC7792240.Ebbeling CB, Feldman HA, Chomitz VR, Antonelli TA, Gortmaker SL, Osganian SK, Ludwig DS. A randomized trial of sugar-sweetenedbeverages and adolescent body weight. N Engl J Med. 2012;367:1407–1416.Ebbeling CB, Feldman HA, Osganian SK, Chomitz VR, Ellenbogen SJ, Ludwig DS. Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: a randomized, controlled pilot study. Pediatrics. 2006;117:673–680.Tordoff MG, Alleva AM. Effect of drinking soda sweetened with aspartame or high-fructose corn syrup on food intake and body weight. Am J Clin Nutr. 1990;51:963–969.Raben A, Vasilaras TH, Moller AC, Astrup A. Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects. Am J Clin Nutr. 2002;76:721–729.de Ruyter JC, Olthof MR, Seidell JC, Katan MB. A trial of sugar-free or sugar-sweetened beverages and body weight in children. N Engl J Med. 2012;367:1397–1406.Maersk M, Belza A, Stodkilde-Jorgensen H, Ringgaard S, Chabanova E, Thomsen H, Pedersen SB, Astrup A, Richelsen B. Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study. Am J Clin Nutr. 2012;95:283–289.de Ruyter JC, Olthof MR, Kuijper LD, Katan MB. Effect of sugar-sweetened beverages on body weight in children: design and baseline characteristics of the Doubleblind, Randomized INtervention study in Kids. Contemp Clin Trials 2012;33:247-57Køster-Rasmussen R. Weight Changes in General Practice. Dan Med J. 2017 Jun;64(6):B5376. PMID: 28566125.

Nutrition Tip Tuesday Can you drink diet coke on your Betterment Journey? Let's talk about it. Give the gift of BETTER this year! 3 Months for $25 https://www.betterdaily.live/shop/black-friday-special-3-month-better-daily-membership Join the Better Daily Family today: https://betterdaily.live Use code "POD" at checkout to save 25% on your subscription

EPISODE 35: SUGAR Hello and WELCOME to the WELLNESS FOURplay Podcast! We are Dr. Dondee & Marci Nettles, former Family Wellness Chiropractor and AM Talk Radio Host (Dondee) and former Police Detective (Marci). We are now investigating all angles of Health and Wellness topics, to share knowledge and empower you to be your own Health Advocate. We know that Knowledge is the foreplay to your Wellness, and we want to equip you to be your own Super Hero on your Wellness journey. In every episode, we ask FOUR questions around a certain Wellness topic, giving you the knowledge you need to have the health you so desire. Here are the four questions this week: 1. WHAT ARE THE DIFFERENT KINDS OF SUGAR AND ARE THERE SOME THAT ARE HEALTHIER THAN OTHERS? 2. WHAT HAPPENS TO THE SUGAR WE CONSUME? 3. WHY DO WE THINK WE NEED SOMETHING SWEET? 4. WHAT CAN HIGH LEVELS OF SUGAR CONSUMPTION LEAD TO? For additional information, please watch “The Truth About Sugar” here: https://youtu.be/9E9bnjwQG9s Please check out our website at https://DondeeAndMarci.com Follow Marci at: https://linktr.ee/MarciNettles Follow Dondee at: https://linktr.ee/DondeeNettles #WellnessFOURPlay #DondeeAndMarci #Sugar #Obesity #Knowledge #TheBiohackingTeam

Top O' the Mornin to Ya Mob! Woot woot! Get out your sweetest two toofs, because we have another delicious double episode made completely of sugar. How many times does Matt start over trying to say "prevent potential contamination"? Try it, it's no easy feat. Is he the new Hamilton? Just how big was that molasses wave brah? Find out now! Today we have for you A Little Sucrose for Comfort which includes: Imperial Sugar Refinery Explosion and Boston Molassacre.  If you like what you hear please tell someone and rate us it does help! Everything is done by the 2 of us, we have no big wigs backing us, the man doesn't have a hand in this baby! so we need YOU!  Stay safe out there and be careful not to find yourself in your own Macabre Reality. Find us on all socials @macabrepod1 and email us at macabrepod1@gmail.com Patreon coming soon....

We look at sugars and appetite with Kathleen Page, MD, associate professor of medicine at the University of Southern California Keck School of Medicine. Dr. Page is the corresponding author of a new article published in The Journal of Clinical Endocrinology and Metabolism, “Appetite-Regulating Hormones Are Reduced After Oral Sucrose vs Glucose: Influence of Obesity, Insulin Resistance, and Sex.” For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.

We look at sugars and appetite with Kathleen Page, MD, associate professor of medicine at the University of Southern California Keck School of Medicine. Dr. Page is the corresponding author of a new article published in The Journal of Clinical Endocrinology and Metabolism, “Appetite-Regulating Hormones Are Reduced After Oral Sucrose vs Glucose: Influence of Obesity, Insulin Resistance, and Sex.” For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.

Randall and Stuart have a pretty sweet episode for you here regarding the chemistry of sucrose. 

In episode 57, I share a lifestyle hack that can provide very quick benefits to your present health, as well as adding many healthy years to your life. This important lifestyle hack is the drastic reduction of refined sugar from your life. Get your free companion PDF 13 Sure-Fire Tips to Eliminate Refined Sugar From Your Life Click on the button below to download your PDF Send me the PDF! Most people are aware that too much sugar can cause health issues like diabetes, childhood obesity, tooth decay and hyper-active kids and that sugary soft drinks are becoming a target for law-makers and TV talk shows trying to curb the proliferation of these serious health issues. But many people are unaware of the pervasive and hidden nature of processed sugar, how it gets into our food, and how damaging it is to our health. This danger is amplified as we enter our middle age and senior years because we become more vulnerable to the many serious diseases of aging such as cancer, diabetes, heart disease and more. Now I'm not demonizing all sugar. Every cell in our body needs sugar. I'm focusing here on the processed sugar that you'll find in sodas and food sweeteners like sucrose and high-fructose corn syrup . We're also looking at fruit and some vegetable juices. This type of sugar is often added to other processed foods like cookies, cereal, pasta sauce, peanut butter and yogurt. These sugars are causing many health issues for many people. And sadly, many people don't even realize that it's in their food. We now know that this kind of sugar can create a strong addiction that works by the same process as does a heroin addiction. It's that insidious. That's why it's so hard for many people to cut down or eliminate sugar from life. The cravings can be very strong. And withdrawing from sugar can cause some pretty nasty symptoms such as anxiety, agitation, insomnia, sweating, fatigue, muscle aches, nausea and vomiting. And the addiction can be so overwhelming that it may require medical intervention. It can take up to 3 months to wean yourself off sugar. So, it's really no joke. So why is processed sugar so addicting? Chowing down on refined sugar causes your body to release dopamine, your body's natural feel-good hormone, which is the same rewards pathway as the addiction to heroin, cocaine, and nicotine uses. Over time you can become very dependent on refined sugar. And as if that isn't bad enough, refined sugar makes you crave more sugar. And fructose is the culprit here. It turns out that refined sugar (sucrose), and high-fructose corn syrup,  contain both fructose and glucose. Sucrose, or table sugar, is made from sugar cane or beets and is about a 50/50 combination of fructose and glucose. High-fructose corn syrup contains about 55% fructose and 45% glucose. Glucose isn't really the bad guy here. It is broken down by every cell in your body and causes your body to release insulin, to break it down and remove it from the bloodstream. This process also release leptin, a protein that helps to make you feel full, thus curbing your hunger. But fructose, does not trigger your body to send the insulin and the leptin. Instead, fructose is broken down inside the liver. The problem is that without the leptin, you still feel hungry, and thus the sugar cravings. Fructose also elevates your triglyceride levels thus elevating your risk for heart attack and stroke. But fructose is derived from fruit. Does that mean that fruit is unhealthy? Not at all. The fructose in fruit is bound up in what they call the food matrix. This means that it's enmeshed with cellular material and fiber. This causes it to be broken down slower and thus doesn't cause the big spikes in your blood sugar. Also, the fiber makes you feel full. But fruit and veggie juices are a different story. You remove the food matrix and are left with mostly fructose, which then becomes the bad guy again adding to your sugar addiction and spikes in your blood sugar. So, avoid fruit juices or consume them in moderation. You should also be aware that many foods will show that they contain NO ADDED SUGAR on the label because they add fruit juice instead. But fruit juice is almost 100% fructose, which is actually less healthy than sucrose. So read the labels carefully. More on that later. So how big of a health problem is the consumption of refined sugar? Very big. Almost 75% of all adults in the United States get a 10% of all their daily calories from refined sugar while 10% of adults get a whopping 25% of all calories from refined sugar. That' a lot of sugar. It is estimated that the yearly cost of sugar-related health conditions on our health care system is over $1 trillion dollars. That's trillion with a capital “T”. In 2010, sugar sweetened beverages, like sodas, were responsible for 133,000 deaths from diabetes and 45,000 deaths from cardiovascular disease, and 6450 from cancer worldwide. This is from sugar free sodas alone. In one study, they found that adults who drank just one soda per day were 46% more likely to develop pre-diabetes. One of the most insidious and dangerous effects of the habitual consumption of processed sugar is its negative effect on your sleep. They now know that consumption of refined sugar adversely affects your quality of sleep causing more fragmented sleep and thus contributing more to sleep deprivation. Now that's only the beginning of your sugar induced problems. It turns out that the lack of sleep only increases your body too feel hungrier all the time due to the suppression of leptin, the hormone that makes you feel full. In fact, sleep deprivation actually causes your body to create hormones that make you feel hungrier. It's a vicious cycle. And worse yet, poor sleep has been shown to make you want to eat junk food more. So, the sugar cycle just gets worse. And we are learning more and more about how proper sleep is really the driver of good health. So, a disturbance in your sleep can have deleterious effects on your health. If you end up in this merry-go-round then your best move may be to seek professional help. It could save your life. And sleep is just the tip of the iceberg when it comes to the negative effects of processed sugar. Let's talk cancer… It seems like every day there is a new link between sugar and cancer. There are studies that show that refined sugar is a factor in almost 1/3 of all cancers worldwide. In another study they found that men tripled their risk of prostate cancer by regularly consuming sugar-sweetened drinks. So how does sugar cause cancer? One way that cancer cells are created in our body is from damage to our DNA.  All of our DNA has protective bumpers at the ends of the DNA strand. These protective bumpers are called telomeres. They've been in the news a lot lately. These telomeres act as protective buffers preventing damage to your DNA. When we are young our telomeres are very long thus making our DNA very resistant to damage. But, as we age, our telomeres get shorter and thus make us more vulnerable to DNA damage. You can accurately determine a person's biological age simply by measuring the lengths of their telomeres. Many things can affect the length of your telomeres. Negative lifestyle factors such as smoking, stress, obesity, poor exercise and poor nutrition can cause shortening of your telomeres. While positive lifestyle factors like low-stress, meditation, good exercise and good nutrition can actually increase the length of your telomeres. Well, refined sugar causes a shortening of your telomeres leading to pre-mature aging and potential DNA damage which increases your risk of cancer. In fact, in one study it was shown that people who drank only one soda per day had the equivalent aging of 4.5 years due to the shortening of their telomeres. That's a high price to pay for a can of soda. We also know that excess refined sugar can cause your gut to produce and accumulate something called beta cotinine, which is a type of gene that normally affects the proliferation of our cells. With too much of the beta cotinine, our worn-out, senescent cells, which normally would go through a natural process of cell death, called apoptosis, are instead made to be immortal, and thus prime candidates to become future cancer cells. Let's talk inflammation… Inflammation is now known to be the driving factor in many of the conditions associated with aging such as cancer, heart disease, neurological diseases like Parkinson's and Alzheimer's, along with many others. Inflammation is caused by our natural immune response to illness, or injury. It's what is causing the swelling, redness, and pain. Reducing inflammation is very important for successful aging. As you would expect now, our nemesis, refined sugar is front and center when it comes to producing inflammation. In one study.  Men who consumed a 20-ounce sugar drink every day for 3 weeks experienced an increase in their inflammation by up to 100%. And men, if you're interested in holding on to your testosterone for as long as possible then you'll want to be cutting down on the processed sugar. In one study, the testosterone of men who consumed the equivalent of a soda and a doughnut, dropped by 25% for up to two hours. So, you may want to avoid that coke if you have some amorous plans in the near future. Does process sugar affect my brain? And, as you may have guessed already, excess sugar consumption can have a profound affect on your brain. Studies have shown that long-term refined sugar intake can have the same negative effects on the brain as some very powerful stimulating drugs, such as amphetamine, cocaine, and nicotine. Effects include brain atrophy, concentration, and emotional and memory problems. Well, I think you get the idea. Refined sugar is really bad for you and well worth reducing and eliminating from your diet. Okay, so I'm ready to take that leap for myself and my family. How do I do it? Great! I'm one step ahead of you here. I have created a companion PDF with 13 tried and true tips that will really enable you to take charge and eliminate your sugar tooth for good. This PDF will arm you with some solid tips that will make your path to reducing your sugar as painless as possible to help ensure your success. Sign up for your FREE PDF below! Get your free companion PDF 13 Sure-Fire Tips to Eliminate Refined Sugar From Your Life Click on the button below to download your PDF Send me the PDF! Okay, I'm on the road to less sugar and better health! When can I expect to see some results? The silver lining to the mass of negative health effects caused by refined sugar is that for many of them, simply removing refined sugar from your diet can quickly start to reverse the damaging trends that the sugar caused. In one study conducted in the UK, people reversed their risk of developing type 2 diabetes by 25% simply by eliminating one sugar sweetened soda per day. Within a few weeks of substantially reducing your processed sugar intake you can expect to see at least a 10% decrease in your LDL cholesterol along with a 20% decrease in trigylcerides. That will make your heart a happy chappy. You will also significantly decrease your chances of developing type 2 diabetes. You will also notice a marked improvement in mood and anxiety. You will find it easier to get off of the bad sleep merry-go-round that is caused by poor diet and lack of sleep. And guess what? No more sugar crashes. You will also be able to win the battle of sugar and sleep-deprived brain fog. Wouldn't that be nice to remember the names of your kids again? You will also get a nice surprise when you jump onto the scale and notice the 10 lbs or more that you lost from giving up the hundreds of additional calories consumed from sugar. You will look and feel years younger, all from taking the leap to adopt this very important lifestyle hack. And the real reward will be the additional years that you'll spend with the people that you love. That has no price. Lastly, here are some foods that contain a lot of hidden sugars Low Fat Yogart No sugar added foods! – Yes, they add fruit juice instead, which is fructose, an added sugar. Crackers Smoothies. Some can contain more than 60 grams of sugar! Alcohol mixers Fruit snacks Nut butter Instant oatmeal Cereals Jam Granola and granola bars Dried fruit Coffee drinks BBQ and other sauces Non-dairy milk Bread Flavored Bottle Water Gummy vitamins Bottled Tea Juice Salad dressing Lemonade Marinade Sports Drinks Jerky Protein Powder Tomato Sauce Energy Bars The list could go on and on… If you need additional support or if you have any questions or comments then you are welcome to contact me via email at Jim@essentialboomer.guide CLICK HERE to help support The Essential Boomer CLICK HERE to join The Essential Boomer Members Community Private Facebook group. It's FREE! And…I would be remiss not to give a big thanks to my favorite blues guitar player of all time, Mr. Dave Hydie for generously providing such a great intro and outro for each of my podcasts. I love you Dave, you da man.  

A new study raises the question, what's the least worst form of sugar? Is it fructose? Sucrose? Glucose? Some combination? This seems like asking, "Who was the less worst mass murdering dictator of the 20th Century, Adolph Hitler or Joseph Stalin?" Does the ranking really matter? For sugar and dictators, the question may have more academic than practical significance. It's a matter of picking your poison.

Sugar Basics Sugar in your blood = glucose Your body prefers glucose over any other sugar out there. -ose = sugar suffix GlucOSE FructOSE - fruit sugar SucrOSE - table sugar SucralOSE - Splenda Your body can turn any of these other sugars in to glucose.  It can actually turn other carbohydrates, and even non-sugar molecules into glucose if it really needs to.  This all happens in your liver... If you were in a long-term starvation or malnutrition situation, your body would circulate non-glucose energy sources to try to get energy, since the process of making glucose can be relatively slow.  This is because your body would prefer to live than die. Brain Food The brain is a picky eater, and refuses to utilize non-glucose sources of energy.  This is because your brain works A LOT!  And it doesn't have time to use inefficient sources of energy.  Therefore, it will hog the glucose from the rest of your body. Your skeletal muscles use glucose to do work.  This is why people with diabetes have to be extra cautious when they exercise. Extra glucose gets saved for those times when you're not eating.  It gets put in a really long chain called glycogen.  But getting the glucose back from the glycogen can be relatively slow. Recovering from an episode of low blood sugar takes time and requires rest (so you're not burning through the fuel as fast as you replenish it).  But it can also be emotionally stressful because you may be required to eat "unhealthy" amounts of sugary or carb-heavy foods to get back to normal. Energy Production Glucose has a very complex metabolism cycle - the Krebs cycle. One intermediate is glucose-6-phosphate (G6P) - there is a genetic mutation where a protein for this step doesn't do it's job very well.  If this step gets delayed or clogged up, then there is a detour metabolism step that leads to triglyceride production, when then leads to fat storage.  *womp womp*  (note: triglycerides are useful in the right amounts for cell repair)  This is also why eating large amounts of sugary plus fatty foods can lead to quick weight gain. The end result of this cycle is Adenosine Triphosphate (ATP).  It is super energetic when a phosphate piece is removed.  It's like the body's dynamite.  This is how a sugar high works - all the sugar leads to all the dynamite exploding at once, but then it takes a while for it to get replenished, and that's why you crash after a sugar-high. Low Blood Sugar is Bad To immediately recover from low blood sugar, you need simple sugar (orange juice, regular soda, sugar-full hard candy, glucose tabs or paste or gel).  To continue to recover, you need carbs plus something that will help it not absorb so fast (i.e. protein, healthy fats). If you ever look at the underside of your tongue, you can see the blood vessels really clearly because they're really close to the surface.  So if someone is unconscious due to low blood sugar, you can use a glucose tablet or gel under their tongue and it will absorb into the blood stream.  This is also how you can absorb sugar quickly from sugar-full gum. Low blood sugar can lead to emotional fluctuations (aka crabby and grouchy) and short-term memory loss (and not just because you passed out). Connect with me Support us on Patreon *NEW* Join the Pharmacist Answers Podcast Community on Facebook Subscribe: iTunes, Stitcher, GooglePlay, TuneIn Radio Like the Facebook page Music Credits:  “Radio Martini” Kevin MacLeod (incompetech.com)  Licensed under Creative Commons: By Attribution 3.0  http://creativecommons.org/licenses/by/3.0/