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When you go to buy a new car, you expect the salesperson to try to upsell you. They want you to add some options or a protection plan. You can expect the same when you go to the department store to buy a new shirt or some pants. Back in my retail days, they called that selling multiples. But I never expected my pharmacist to try to upsell me. Yesterday, when I finally was able to fill my eye drop prescription, the tech kept pushing me to schedule a Prevnar vaccine. They strongly recommend that everyone over 50 get one. And when I say strongly, I'm serious... Click Here To Subscribe Apple PodcastsSpotifyAmazon MusicGoogle PodcastsTuneIniHeartRadioPandoraDeezerBlubrryBullhornCastBoxCastrofyyd.deGaanaiVooxListen NotesmyTuner RadioOvercastOwlTailPlayer.fmPocketCastsPodbayPodbeanPodcast AddictPodcast IndexPodcast RepublicPodchaserPodfanPodtailRadio PublicRadio.comReason.fmRSSRadioVurblWe.foYandex jQuery(document).ready(function($) { 'use strict'; $('#podcast-subscribe-button-13292 .podcast-subscribe-button.modal-68121450d9c62').on("click", function() { $("#secondline-psb-subs-modal.modal-68121450d9c62.modal.secondline-modal-68121450d9c62").modal({ fadeDuration: 250, closeText: '', }); return false; }); });
There are more than 100 known kinds of pneumococcal bacteria. They can cause serious infections in the lungs and other parts of the body. Each year, the U.S. sees about 30,000 cases of pneumococcal disease, which includes blood infections, brain and spine inflammation, and other problems. About 30 percent of cases are among people aged 50 to 64. 有100种已知类型的肺炎球菌细菌。 它们可能在肺部和身体其他部位引起严重的感染。 每年,美国都会看到大约30,000例肺炎球菌疾病,其中包括血液感染,脑和脊柱炎症以及其他问题。 大约30%的病例是50至64岁的人群。 The first pneumococcal vaccine was licensed in the U.S. in 1977. Since then, drugmakers have been coming up with newer versions that target several bacteria in a single shot. 1977年,第一种肺炎球菌疫苗在美国获得了许可。从那时起,制药商就提出了较新的版本,这些版本针对几种细菌。 There are four vaccines now in use. They include Prevnar 20 from Wyeth-Pfizer, and Vaxneuvance and Pneumovax 23 made by Merck. The U.S. Food and Drug Administration this year also approved Merck's Capvaxive, which can cost around $300 a treatment. The new shot can protect against 21 kinds of bacteria, including eight not included in other pneumococcal vaccines. A Merck spokesperson said it is designed to help protect against the bacteria that cause the majority of severe disease in adults aged 50 and older.现在有四种疫苗正在使用。 它们包括来自Wyeth-Pfizer的Prevnar 20,以及由Merck制造的VaxNeuvance和Pneumovax 23。 今年美国食品药品监督管理局还批准了默克的Capvaxive,该公司的每处理费用约为300美元。 新镜头可以预防21种细菌,其中包括其他肺炎球菌疫苗中未包含的8种。 默克公司发言人说,旨在帮助预防50岁及以上成年人的大多数严重疾病的细菌。In June, the CDC advisors recommended the vaccine as a possible shot for adults at higher risk. At the time, the group also talked about the possibility of lowering the age recommendation for older adults. They noted that infections causing sickness peak at age 55 to 59 among Black Americans — a lower age than found among white Americans. 6月,CDC顾问建议该疫苗可能是面对较高风险的成年人的可能性。 当时,该小组还谈到了降低老年人年龄建议的可能性。 他们指出,在黑人美国人中导致疾病峰值55至59岁的感染峰 - 比美国白人的年龄低。 Some scientists have concerns about the CDC recommendation. They say a second treatment, called a booster, may be necessary in about 15 years. And some new vaccines in development could force another update to the recommendations. 一些科学家对CDC建议感到担忧。 他们说,在大约15年内可能需要第二次称为助推器的治疗方法。 开发中的一些新疫苗可能会迫使建议另一项更新。 Dr. Jamie Loehr is the chair of the committee's pneumococcal working group. He was the only person to vote against the proposal. 杰米·洛尔(Jamie Loehr)博士是委员会肺炎球员工作组的主席。 他是唯一反对该提案的人。 He said, “Pneumococcal has been a very confusing recommendation for many, many years and it's hard to have a new recommendation every two or three years.” 他说:“多年来,肺炎球菌一直是一个非常令人困惑的建议,很难每两三年提出新的建议。”
Send us a textDr. Gregg Sylvester, MD is Chief Health Officer and Vice President, Medical Affairs, at CSL Seqirus ( https://www.cslseqirus.us/our-company/leadership/gregg-sylvester ), one of the world's largest influenza vaccine companies.Dr. Sylvester has led CSL Seqirus Medical Affairs since 2016, overseeing the global team that scientifically differentiates company's vaccines by generating Real World Evidence and presenting CSL Seqirus research to national vaccine recommending organizations. Dr. Sylvester has extensive experience in the pharmaceutical industry, government and patient care. Prior to joining CSL Seqirus, Dr. Sylvester led Medical Affairs teams at Pfizer and Merck involved in the worldwide launches of vaccines including Gardasil (Human Papillomavirus Vaccine), Prevnar 13 (Pneumococcal Conjugate Vaccine) and Trumenba (Meningococcal Group B Vaccine). Dr. Sylvester obtained specialty boards in Pediatrics and General Preventive Medicine. Augmenting his clinical expertise, he served in the CDC Epidemic Intelligence Service and as a Public Policy Fellow in the U.S. Congress. During his distinguished career in state government, Dr. Sylvester was appointed to the Cabinet Secretary for Health and Social Services in Delaware, leading the state's largest agency. Dr. Sylvester has a MD from Albany Medical College and an MPH from the Johns Hopkins Bloomberg School of Public Health.#GreggSylvester #CSLSeqirus #Influenza #Vaccine #FluShot #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show
Guest: Dr. Shankar Musunuri - Ocugen, Chairman, Chief Executive Officer, and Co-founder Website: www.ocugen.com Ticker: OCGN Bio: Dr. Shankar Musunuri is Chairman, CEO and Co-Founder of Ocugen. The company (NASDAQ: OCGN) is a publicly traded biotechnology company focused on discovery, development, commercialization of gene therapies, cell therapies, biologicals, and vaccines, based in Malvern, Pennsylvania. Dr. Musunuri transformed Ocugen from a start-up into a cutting-edge science-based biotech powerhouse with three distinct first-in-class platform technologies focused on ophthalmology with a first-in-class modifier gene therapy platform targeting rare as well as large blindness diseases, orthopedics with a regenerative cell therapy platform, and infectious diseases with an inhalation vaccine platform targeting Covid-19, flu, and a combination vaccine for both COVID-19 and flu. Ocugen anticipates launching products from these game-changing platform technologies within the next few years. The company's mission is to develop cutting-edge innovations for people with serious diseases and conditions with a commitment to ensuring global market access. Dr. Musunuri is a seasoned biotech veteran with 30+ years' experience advancing and commercializing a diverse portfolio of products. Prior to co-founding Ocugen in 2013, he held leadership roles at numerous companies ranging from large multinational biotechnology companies such as Wyeth and Pfizer, to novel start-up biotech companies. During his 15 years at Pfizer, he gained extensive product launch and life-cycle management experience including leading the Global Operations Team for Prevnar 13, the world's best-selling vaccine. Dr. Musunuri then founded Nuron Biotech, Inc., which grew into a commercial company in less than three years. Dr. Musunuri obtained his PhD in Pharmaceutical Sciences from the University of Connecticut—where he also received a Distinguished Alumnus Award. He also received an MBA from Duke University, where today he serves on the University's Innovation & Entrepreneurship Board of Advisors. Dr. Musunuri serves as both CEO and Chairman of the board of Ocugen. He has received numerous leadership awards including Most Admired CEO Award by Philadelphia Business Journal, the 2023 Healthcare Power 100 (ranked 22nd) in PA and the 2023 AAPI Power 100 (ranked 11th) in PA. He is also a Board Member of the Musunuri Family Foundation, a non-profit that provides college scholarships for high school students. Dr. Musunuri has a passion for addressing diseases and conditions which lack effective treatments. This commitment is reflected in Ocugen's mission of relentlessly pursuing courageous innovation on behalf of patients with unmet medical needs. About Ocugen, Inc. Ocugen, Inc. is a biotechnology company focused on discovering, developing, and commercializing novel gene and cell therapies, biologics, and vaccines that improve health and offer hope for patients across the globe. We are making an impact on patients' lives through courageous innovation—forging new scientific paths that harness our unique intellectual and human capital. Our breakthrough modifier gene therapy platform has the potential to treat multiple retinal diseases with a single product, and we are advancing research in infectious diseases to support public health and orthopedic diseases to address unmet medical needs. Discover more at www.ocugen.com --- Support this podcast: https://podcasters.spotify.com/pod/show/smartmoneycircle/support
US equity markets rallied, buoyed by fresh gains for the technology sector - Dow rose +189-points or +0.49% to snap a four session losing streak, with Apple Inc (up +1.97%) the leading performer in the 30-stock index after scrapping its “buy now, pay later” service, which it launched in the US only last year. The tech giant says it is pivoting to a new instalment loans service offered through third-party credit and debit cards. Merck & Co rose over >1% in after-hours trading (having declined -0.94% in the regular session) after receiving US regulatory approval for its next-generation vaccine (Capvaxive) to protect adults from pneumococcal disease, which is set to challenge Pfizer Inc's (down -2%) blockbuster Prevnar shot.
US equity markets rallied, buoyed by fresh gains for the technology sector - Dow rose +189-points or +0.49% to snap a four session losing streak, with Apple Inc (up +1.97%) the leading performer in the 30-stock index after scrapping its “buy now, pay later” service, which it launched in the US only last year. The tech giant says it is pivoting to a new instalment loans service offered through third-party credit and debit cards. Merck & Co rose over >1% in after-hours trading (having declined -0.94% in the regular session) after receiving US regulatory approval for its next-generation vaccine (Capvaxive) to protect adults from pneumococcal disease, which is set to challenge Pfizer Inc's (down -2%) blockbuster Prevnar shot
In der 78. Folge des Infektiopods berichten wir von aktuellen, „practice changing“ Neuerungen bei Impfstoffen. Als erstes geht es um den neuen, 20-valenten Konjugat-Impfstoff PCV20 gegen Pneumokokken („APEXXNAR“ in EU, „PREVNAR 20®“ in USA) Als zweites geht es um Impfstoff-Updates gegen das Respiratorische Synzytialvirus (RSV) und zwar zunächst die aktive Impfung „mRNA 1345“ von Moderna … „Infektiopod 78: Impfstoff-Update Pneumokokken, RSV & Dengue“ weiterlesen
1/13/24 - Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics, Including: a look at all the Viruses out there now and is it too late for Vaccinations? Dr. Ken explains how Paxlovid works with COVID, how your muscles might change after Long COVID, The American Red Cross warns that blood supplies are now at a 20 year low, Weed can make it tougher to exercise, getting poor sleep in your 30s and 40s can affect how your brain works 10 years later, Morning Sickness comes from hormones inside the fetus, Prevnar 20 showing success in preventing Pneumonia.
Pediatrician Dr. Jill Schaffeld consults Dr. Bob Frenck on recent movement in pediatric immunizations - Niresvimab (Beyfortus) for RSV, single dose Covid-19 vaccinations, and Prevnar-20. Episode recorded on August 17, 2023.
Host: Joyce Riley Guest: Lance Sloan, MD Pneumococcal vaccination isn't restricted to a specific season. Patients can get vaccinated with Prevnar 20 at any time. Clinicians can help their patients better understand the importance of pneumococcal vaccination. Join Joyce Riley as she gets expert insights from Dr. Lance Sloan, Endocrinologist, Nephrologist, and Metabolist in Lufkin, Texas. Continuing medical education credits are not available for this program.© 2023 Pfizer Inc. All rights reserved. PP-PRV-USA-0378
Host: Joyce Riley Guest: Lance Sloan, MD Pneumococcal vaccination isn't restricted to a specific season. Patients can get vaccinated with Prevnar 20 at any time. Clinicians can help their patients better understand the importance of pneumococcal vaccination. Join Joyce Riley as she gets expert insights from Dr. Lance Sloan, Endocrinologist, Nephrologist, and Metabolist in Lufkin, Texas. Continuing medical education credits are not available for this program.© 2023 Pfizer Inc. All rights reserved. PP-PRV-USA-0378
The Federal Reserve raised its benchmark interest rate to the highest level in 15 years by half a percentage point. Officials expect to keep rates higher through next year, with no reductions until 2024.According to a draft law to amend some provisions of the income tax law, the Egyptian government intends to impose a new tax bracket of 27.5% on individuals' income that exceeds EGP800,000 annually (USD32,000). The draft also includes:Bypassing the unpaid capital gains tax due on the disposal of shares listed on EGX during the period from January 2022 until the date of entry into force of the law's amendments.Deducting 50% of the capital gains achieved for individuals from the initial offerings, for a period of two years from the date of entry into force of the amendments to the income tax law. The Egyptian government aims to increase its tax revenue during the current fiscal year 2022-2023 by about 18.8%. It also seeks to increase its revenues from payroll tax by 18.6%.Retailers have two weeks to start clearly displaying the prices of all their goods under efforts aimed to tame food price inflation.To make it easier for Egyptians living abroad to buy a car under the government's new car import scheme, buyers will no longer be required to deposit fees for the program three months before transfers are made. They can instead provide to the government with a bank statement as proof of their ability to pay.The Cabinet awarded golden licenses to eight investment projects including a USD5.5 billion green ammonia plant in Ain Sokhna. Egypt targets increasing exports to Africa to USD10 to 15 billion within four years. Oil prices increased on Wednesday after OPEC and the International Energy Agency (IEA) forecast a rebound in demand over the course of next year and as US interest rate hikes are expected to ease further alongside slowing inflation.The 100 MW green hydrogen plant being developed by Scatec, Fertiglobe and ORAS (FV: EGP106.90, OW) received a license from cabinet yesterday. The EGX has approved the temporary listing of the Damietta Container & Cargo Handling Company's shares ahead of a potential IPO next year.Haleon — the former consumer healthcare unit of GSK that was spun off over the summer — will kick off operations under its own brand in Egypt next year. Haleon Egypt will locally produce 90% of its products.Drugmaker Pfizer is in talks with the government to manufacture its Prevnar vaccine in Egypt, which is designed to treat pneumonia.Eva Pharma and Lilly will partner to produce insulin for diabetes patients in the local market.CBE data revealed that the value of its assets increased to EGP3.7 trillion at the end of November 2022 (+5.7% MoM). Moreover, balances with the IMF recorded EGP7.105 billion (-39% YoY). The banking sector customer deposits increased, to record EGP7.82 trillion at the end of September (+1.3% MoM), while lending balances reached EGP3.695 trillion at the end of September (+2.8% QoQ)
Pediatrician Dr. Jill Schaffeld consults Dr. Bob Frenck on vaccines. The discussion ranges from the Prevnar-15 release to Covid-19 to vaccine hesitancy among parents. Episode recorded on August 11, 2022. CME & MOC Part 2 We are proud to offer CME and MOC Part 2 from Cincinnati Children's. Click this link to go to the page for credit. Credit is free and registration is required. Resources discussed in this episode: Covid-19 Toolkit for PCPs Cincy PCP Covid Updates
Episode 90: Vaccines and Acne. Updates on pneumococcal and COVID-19 vaccines. Sarah explains the treatment of acne.New Pneumococcal Vaccine Recommendations. Written by Harkiran Bhattal, MS4, Ross University School of Medicine; Timiiye Yomi, MD; and Hector Arreaza, MD.During the recording, we used brand names because they are easier to use. We are not sponsored by the manufacturers of these vaccines. Terminology of pneumococcal vaccines: PCV13: Prevnar13®PPSV23: Pneumovax23®PCV15: Vaxneuvance® PCV20: Prevnar20®Tips about pneumococcal vaccines:-Prevnar13 is no longer used in adults. -Pneumovax23 is still being used in adults.-The two newer members of the pneumococcal vaccines are: Prevnar20® (PCV20) and Vaxneuvance® (PCV15). The following groups of patients are all adults 19-64 with underlying conditions OR >65 years old. Group A: Unknown or no prior doses of Prevnar13 or Pneumovax 23Option 1: Prevnar20 given as a single doseOption 2: Vaxneuvance followed by a dose of Pneumovax23 at least a year later (Consider >8 weeks in patients >19 at the highest risk)Group B: Previously received Pneumovax 23Give Prevnar20 or Vaxneuvance (at least 1 year since the last Pneumovax 23)Group C: Previously Received Prevnar13Give Pneumovax23 or Prevnar20 (if Pneumovax 23 is not available) >1 year since last dose of Prevnar13Group D: Previously completed series of Prevnar13 and Pneumovax23 in any orderNo additional doses are needed. Scenario 1: 68 yo M who has not previously received PCV or whose previous vaccination history is unknown (Group A). This patient should receive: 1 dose of Prevnar20 and be done, or Vaxneuvance followed by a dose of Pneumovax23. Scenario 2: 25 yo F with HIV not previously received PCV or whose vaccination history is unknown (Group A). This patient should receive: 1 dose of Prevnar20 and be done, or Vaxneuvance followed bya dose of Pneumovax 23 given 8 weeks later. This patient is in the highest risk group. Scenario 3: 50 yo M with chronic alcoholism who has not received any vaccine or unknown status (Group A). This patient should receive: 1 dose of Prevnar20 and be done, or Vaxneuvance followed by Pneumovax 23 one year later. Scenario 4: 43 yo M with previous Pneumovax 23 only (Group B). This patient should receive either: a single dose of Prevnar20 or Vaxneuvance and be done with either vaccine. Give either vaccine at least 1 year after Pneumovax 23. Scenario 5: 25 yo F with CSF leak and previously received Prevnar13 (Group C). This patient should receive Pneumovax23 or Prevnar 20 (if Pneumovax 23 is unavailable) at least one year after her las Pneumovax dose. Scenario 6: 35 yo M who previously completed Prevnar13 and Pneumovax in any order because he has a cochlear implant (Group D). This patient should NOT receive any additional dose. Research and MonitoringCDC and ACIP will continue to assess the safety of Vaxneuvance and Prevnar20 vaccines (the new kids on the block), monitor the impact of the implementation of new recommendations, and assess post-implementation effectiveness and recommendations as appropriate. Examples of risk factors to consider administration of pneumococcal vaccines: Chronic renal failure, HIV infection, alcoholism, cigarette smoking, chronic heart, liver, and lung disease. For a complete list of conditions, visit CDC.gov.___________________ A second booster shot of COVID-19 vaccines. By Hector Arreaza, MD.On March 29 and 30, 2022, CDC announced that a second booster dose of any mRNA COVID-19 vaccine may be given to certain individuals who are at risk of severe outcomes from COVID-19(1). Individuals who may choose to receive a second booster are: 1. People older than 12 years of age who have a moderate to severe immunocompromising condition. Remember, use Pfizer for older than 12 yo, and Moderna for older than 18 yo.2. People older than 50 years of age who are NOT moderately or severely immunocompromised.3. People 18-49 years of age who are NOT immunocompromised but received the J&J COVID-19 vaccine as both the primary and booster dose. When can you receive the second booster shot? At least 4 months after the first booster dose.Who is considered up to date? A person is considered up to date when he/she has received all recommended doses in their primary vaccine series, and a booster dose when eligible. A second booster dose is not required to be considered up to date at this time.Underlying medical conditions associated with higher risk for severe COVID-19 include: Cancer, obesity, cerebrovascular disease, diabetes mellitus, HIV, obesity, COPD, smokers, and chronic liver disease.Comment: Remember to give the second booster to your patients. ____________________Acne Treatment. By Sarah Park, MS3, University of California Los Angeles. Discussed with Hector Arreaza, MD. Definition: Acne vulgaris is a common inflammatory disorder of the pilosebaceous unit, which includes the hair follicle and sebaceous gland. It is characterized by chronic or recurrent development of papules, pustules, or nodules commonly on the face, chest, or upper back.(1,2) Acne affects nearly 50 million people in the U.S. per year and can cause significant psychological distress in those who are affected. It primarily begins at puberty when the production of androgens and/or sensitivity of androgen receptors increase, thereby commonly affecting adolescents and young adults.(2) Pathophysiology: The pathophysiology of acne involves four main processes: 1) sebum overproduction, 2) hyperkeratinization of the follicle, 3) bacterial colonization by Cutibacterium acnes, and 4) inflammation.(2,3) It can be classified as mild, moderate, or severe based on the extent and types of lesions.3Treatment: Treatment is selected based on the severity of the condition, patient preference, and tolerability. Acne treatment often requires long-term, consistent use of one or more medications.(3) The main objective of treatment is to decrease sebum production, get rid of extra keratin, treat infection and decrease inflammation. You can warn your patients that their skin may feel dryer and more scaly than usual, but that's part of the treatment. For mild and exclusively comedonal acne, topical retinoids like tretinoin are the treatment of choice(4), but topical retinoids can be used in any level of severity for maintenance. Examples: Adapelene, tazarotene, and tretinoin, For mild inflammatory papulopustular acne or mild mixed comedonal and papulopustular acne, topical retinoids may be used in combination with antimicrobial therapy (either combined with benzoyl peroxide or combined with benzoyl peroxide plus clindamycin or erythromycin). If patients cannot tolerate a topical retinoid, alternatives include salicylic acid and azelaic acid. Of note, oral or topical antibiotics should only be used in combination with benzoyl peroxide and retinoids for a maximum of 12 weeks. If unresponsive to these topical therapies, namely retinoids, benzoyl peroxide, and/or clindamycin, alternative therapies may be initiated. These include topical dapsone, minocycline, and clascosterone.Topical dapsone is an effective treatment for both inflammatory papulopustular and comedonal acne lesions. Topical minocycline is an alternative topical antibiotic used for specifically moderate to severe acne. And last but not least is topical clascosterone, a relatively new topical (specifically an androgen receptor inhibitor) approved by the FDA in 2020.(4)Treatment for moderate to severe acne: For moderate to severe acne vulgaris, management is systemic therapy. This includes oral antibiotics or hormonal therapies, often used in conjunction with topical therapy, or monotherapy with oral isotretinoin. 1. Oral antibiotics for acne vulgaris include doxycycline, minocycline, and sarecycline. Treatment should be limited to three to four months.(5)2. For female patients, hormonal therapy with oral contraceptives and/or spironolactone is also an option. A meta-analysis comparing oral contraceptive therapy and oral antibiotic therapy suggests similar efficacy for the treatment of acne. OCP treatment is often the first-line choice for hormonal therapy, especially for patients who desire the added benefit of contraception. Spironolactone is often used for patients who have contraindications to OCP therapy or prefer to avoid OCPs. Both methods work to inhibit acne by reducing the effects of androgen on the pilosebaceous unit.53. For severe, extensive, nodular acne vulgaris, oral isotretinoin is the drug of choice. It is given as a monotherapy and is often used when all other treatment modalities fail. Oral isotretinoin is the only medication that can permanently affect the natural course of acne by affecting all four factors in acne pathogenesis. Isotretinoin is most notably known for its teratogenic adverse effects and so is contraindicated in pregnant women and pregnancy must be avoided during therapy by using two forms of birth control.(5)Comment about isotretinoin use: Although prescribing isotretinoin (brand name Accutane®) is within the scope of family medicine, many providers choose not to prescribe it because of lack of training, monitoring hassles, fear of side effects, especially due to concerns with teratogenicity. Isotretinoin is an effective treatment for a condition that can not only disfigure and scar the face but can also cause significant psychosocial dysfunction. Dr. Van Durme recommended when you prescribe isotretinoin, you should have a regular schedule of monthly laboratory tests (including pregnancy test), then office visit, and then prescription, in that order. This schedule will improve the likelihood that side effects are managed promptly and medication is taken appropriately(7). If you would like more information about prescribing isotretinoin, visit https://ipledgeprogram.com.Conclusion: Use topical retinoids alone for mild cases of acne; topical retinoids combined with benzoyl peroxide or topical clindamycin or erythromycin for moderate cases; and topical retinoids combined with benzoyl peroxide and oral antibiotics in severe cases. Remember that isotretinoin is an oral treatment reserved for severe inflammatory papules and pustules with nodules. Treating acne effectively can certainly improve the quality of life of your patients. Now we conclude Episode 90 “Vaccines and Acne”. We gave you an update on pneumococcal and COVID-19 vaccines. Prevnar 20 seems to be the new star in the show. PCV15 is also useful but it needs to be followed by a shot of Pneumovax 23. Regarding COVID-19 vaccines, a second shot may be given to patients older than 12 who are immunocompromised or patients older than 50 who are NOT immunocompromised. Then we finished with a discussion about acne and we learned that topical is usually enough for mild cases, but oral therapy may be needed in moderate to severe cases of acne. Even without trying, every night you go to bed being a little wiser. Thanks for listening to Rio Bravo qWeek. Send us your feedback by email to RioBravoqWeek@clinicasierravista.org, or in our website riobravofmrp.org/qweek. This podcast was created for educational purposes only. Visit your primary care physician for additional medical advice. This week we thank Hector Arreaza, Timiiye Yomi, Amardeep Chetha and Sarah Park. Audio edition: Suraj Amrutia. See you next week! References:Kobayashi M, Farrar JL, Gierke R, et al. Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2022. MMWR Morb Mortal Wkly Rep 2022;71:109–117. DOI: http://dx.doi.org/10.15585/mmwr.mm7104a1 2. Pneumococcal Vaccination Timing for Adults, CDC. https://www.cdc.gov/vaccines/vpd/pneumo/downloads/pneumo-vaccine-timing.pdf, accessed on March 30, 2022. Interim Clinical Considerations for Use of COVID-19 Vaccines, Centers for Disease Control and Prevention, CDC.gov, https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html#considerations-covid19-vax-booster, accessed April 5, 2022. Thiboutot, Diane, MD; and Andrea L Zaenglein, MD. Pathogenesis, clinical manifestations, and diagnosis of acne vulgaris, UpToDate. Accessed on April 1, 2022. https://www.uptodate.com/contents/pathogenesis-clinical-manifestations-and-diagnosis-of-acne-vulgaris Leung AK, Barankin B, Lam JM, Leong KF, Hon KL. Dermatology: how to manage acne vulgaris. Drugs Context. 2021 Oct 11;10:2021-8-6. doi: 10.7573/dic.2021-8-6. PMID: 34691199; PMCID: PMC8510514. Oge' LK, Broussard A, Marshall MD. Acne Vulgaris: Diagnosis and Treatment. Am Fam Physician. 2019 Oct 15;100(8):475-484. PMID: 31613567. Graber, Emmy, MD, MBA. Acne vulgaris: Overview of management, UpToDate. Accessed on April 1, 2022. https://www.uptodate.com/contents/acne-vulgaris-overview-of-management Harris C. Clascoterone (Winlevi) for the Treatment of Acne. Am Fam Physician. 2021 Jul 1;104(1):93-94. PMID: 34264597. Acne vulgaris: Management of moderate to severe acne, UpToDate. Accessed on April 1, 2022. https://www.uptodate.com/contents/acne-vulgaris-management-of-moderate-to-severe-acne Van Durme DJ. Family physicians and accutane. Am Fam Physician. 2000 Oct 15;62(8):1772, 1774, 1777. PMID: 11057835. https://www.aafp.org/afp/2000/1015/p1772.html
Dr. Emilio A. Emini, Ph.D. is the CEO of the Bill & Melinda Gates Medical Research Institute (https://www.gatesmri.org/), a non-profit organization dedicated to the development and effective use of novel biomedical interventions addressing substantial global health concerns, for which investment incentives are limited, and he leads the Institute's research and development of novel products and interventions for diseases disproportionately impacting the world's most vulnerable populations. Before joining the Gates MRI, Dr. Emini served as director of the HIV and Tuberculosis program at the Bill & Melinda Gates Foundation, where he led the foundation's efforts focused on accelerating the reduction in the incidence of HIV and TB in high-burden geographies, with the goal of achieving sustained epidemic control. Over the course of his previous 30-year career in the bio-pharmaceutical industry, Dr. Emini led teams involved in the research and development of novel anti-infectives and vaccines. From 1983 to 2004, he led research at the Merck Research Laboratories involved in the development of one of the first highly active anti-retroviral therapies for HIV and, as senior vice president of vaccine research, the successful development of a number of vaccines including vaccines for human papillomavirus and rotavirus. Dr. Emini later served as senior vice president of vaccine development at the International AIDS Vaccine Initiative. From 2005 to 2015, he was senior vice president of vaccine R&D at Pfizer Inc., leading the development of Prevnar 13® for prevention of pneumococcal disease. Dr. Emini was awarded the Distinguished Alumnus Award from the Weill Cornell University Graduate School of Medical Sciences in 2006. He is a former trustee of the National Foundation for Infectious Diseases and a former member of the National Preparedness & Response Science Board, an advisory committee to the U.S. Secretary of Health and Human Services. He is an elected fellow of the American Academy of Microbiology, International Society for Vaccines, and The College of Physicians of Philadelphia. He received his Ph.D. in Microbiology, Genetics, and Biochemistry from the Weill Cornell University Graduate School of Medical Sciences.
New update! Goodbye Pneumovax 23. Hello PCV 20. Prevnar is back, baby?
On this episode, we discuss treating community-acquired pneumonia. We start with the outpatient treatment options based on the 2019 IDSA CAP guidelines. We also discuss managing a patient that has been admitted. We review some reasons to use more broad-spectrum empiric therapy, and close by mentioning the new Prevnar 20 vaccine. We want to thank the sponsor of this episode, Pyrls. Pyrls is a new drug information (for healthcare professionals or students only) resource for the next-generation of healthcare providers to learn about commonly prescribed medications. Quickly learn or reference counseling points, clinical pearls, comparison charts, and much more by visiting their website or by downloading the mobile app for iOS or Android. Right now, Pyrls is offering a free chart bundle to all of our podcast listeners and Instagram followers. All you have to do is visit the website www.pyrls.com/corconsultrx. The downloadable PDF contains 10 different charts and reference guides. They cover the A1c lowering abilities of the various medication classes, provide some kinetics for the different insulins, compare and contrast CV safety data for the newer treatment classes, list storage and stability information, and so much more! You are not obligated to purchase a subscription to Pyrls. The charts are a free gift for simply checking out the site. Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable Power Point slides for each lecture. You can find our account at the website below: www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.
Pfizer's History of Crimes and Misdemeanors Richard Gale and Gary Null Progressive Radio Network, March 10, 2021 Whenever it is necessary to make an evaluation of the efficacy and safety of conventional drug-based medicine, it is imperative to include the rising rate of iatraogenic injuries and deaths – medical errors – that has become the third leading cause of death in the US after cardiovascular disease and cancer. The majority of these deaths are caused by FDA approved drugs' adverse effects and when patients are prescribed multiple medications in the absence of thorough clinical research to determine the safety of their synergistic effects. Consequently our health agencies' oversight and monitoring of drugs on the market is dismal and deadly. Among the top pharmaceutical companies whose drugs and products have most contributed to the nation’s iatrogenic epidemic is the $51 billion multinational behemoth Pfizer Inc, the world’s third most profitable drug maker. Pfizer is one of America’s oldest pharma firms, founded by Charles Pfizer and Charles Erhart in a Brooklyn red brick building in 1849. The chemical company began to boom in the 1880s after becoming the leading manufacturer of the chelating, flavoring and preservative agent citric acid. With its expertise in fermentation chemistry, Pfizer later became a leader in the production of penicillin and ascorbic acid (Vitamin C). Today its 300-plus drugs are commonplace in American doctors’ tool kits: Zoloft, Zantac, Viagra, Enbrel, Flagyl, Lipitor, and several antibiotics. It is also a major player in the generic drug market and is rapidly becoming a leading vaccine maker with its pneumococcus vaccine (Prevnar) and more recently with its controversial mRNA vaccine against the SARS-CoV2 virus. In the irrational panic to quickly get a vaccine against the SARS virus to market, its Covid-19 vaccine was the first to receive emergency use authorization Pfizer's legacy of lawsuits goes back to the late 1950s. According to the Corporate Research Project, it “has been at the center of controversies over its drug pricing for more than 50 years.” Back in 1958 it was charged by the Federal Trade Commission for price fixing and making false statements to dubiously acquire a patent for tetracycline. Two years later the Justice Department filed criminal antitrust charges against Pfizer’s board chairman and president John McKeen on the matter. Again in 1996, the drug company paid out $408 million to settle another lawsuit for price fixing and gouging pharmacies. In 2002, Pfizer was caught defrauding the federal Medicaid program for over-charging its flagship cholesterol drug Lipitor. Other similar charges include a $784 million settlement for underpaid rebates to Medicaid and $107 million fine for overcharging its epilepsy drug phenytoin sodium. The company has even stooped so low as to engage in bogus advertising. Shortly after the Second World War, Pfizer created snazzy ads for the Journal of the American Medical Association for its antibiotic line. The ads included named physicians endorsing its drugs. However, according to a Saturday Review investigation, the doctors turned out to be completely fictitious. As the company is positioned to earn $19 billon from its Covid-19 vaccine, at the same time it is legally battling against hundreds of lawsuits due to its popular heartburn drug, Zantac, being contaminated with the carcinogen N-nitrosodimethylamine (NDMA), an “extremely hazardous” toxin used in rocket fuel and industrial lubricants. Although the FDA erroneously claims that Zantac’s NDMA levels are low, they have still been measured to be between 3,000 and 26,000 times higher than the FDA’s safety cut-off point. Another adverse effect of NDMA is hepatotoxicity leading to liver fibrosis and scarring. According to the law firm Matthews and Associates, since “the history of Pfizer is rife with so much subterfuge and under-the-table dealing that the company will need all the help it can get to promote confidence in its hastily assembled Covid vaccine.” If the mainstream media were to honestly cover the NDMA trial underway and other Pfizer confrontations with the law, perhaps its vaccine would not be receiving such uncritical fanfare. There would be more scrutiny and warranted suspicion to question how Pfizer could have developed a truly safe and effective vaccine in such a short period of time. In our earlier reviews of the criminal records of Merck and Johnson and Johnson, we did not find evidence of the depths of demented ethical behavior solely to manipulate its market control as we do with Pfizer. In fact, Pfizer seemingly is in competition to outdo notorious hedge fund vulture capitalist and underworld strategies to bully governments in return for securing supplies of its Covid-19 vaccine. For example, Pfizer demanded that Argentina pay the company compensation for any civil lawsuits filed against it. The government compromised and ruled that Pfizer would only pay fines for any negligence on the company’s behalf with respect to supply and distribution. But that was not agreeable to the vaccine maker. Instead it then demanded that Argentina provide its sovereign assets –bank reserves, military bases and embassy buildings – as collateral to secure vaccine supplies. In Brazil, Pfizer’s aggressive and malignant efforts failed. It demanded that the Brazilian government turn over a guaranteed fund deposited in a foreign bank account and that the government would waive its sovereign assets abroad. Pfizer also demanded that it not be held legally liable for any injuries or deaths due to its vaccine. Correctly, President Bolsonaro called Pfizer’s demands “abuse” and rejected the deal. If this gives the impression that Pfizer is a serial predator on poorer foreign nations, Argentina and Brazil are only the most recent examples. In 1996, the company conducted illegal experimental trials with an unapproved experimental antibiotic, Trovan, on Nigerian children without parental knowledge or consent. The case was not raised in a US federal court until 2001 after thirty Nigerian families sued. After 100 children were given the drug as guinea pigs, “eleven children in the trial died, others suffered brain damage, were partly paralyzed or became deaf.” Nigerian medical experts ruled that Pfizer violated international law and the US federal case was eventually settled a decade later for an undisclosed amount. Pfizer’s dirty politics and mafia-like activity in the Nigeria scandal, reminding us of Monsanto’s sleazy schemes, goes beyond the dangers of an experimental antibiotic. Wikileaks made available State Department cables showing that Pfizer had hired spies to dig up dirt to frame a former Nigerian attorney general in order to get the lawsuit dropped. It also tried to shift the blame of the scandal on Doctors Without Borders by making a false claim that the non-profit charitable group was responsible for dispensing the antibiotic. Already in the US, thanks to Reagan’s Vaccine Injury Compensation Act, vaccine makers are off the hook for being held legally accountable for vaccine adverse effects. Now the company is demanding that other nations change their laws solely for Pfizer to secure maximum profits from its Covid vaccine. Pfizer’s actions are utterly parasitical. Nor should we forget that the development of its vaccine has largely been publicly funded. Its Covid vaccine partner Biontech received $445 million from the German government, and Pfizer has received almost $2 billion from US taxpayers as pre-payment for a vaccine. Pfizer’s leech-like behavior goes back even further. In 2003, after it appeared that Congress might pass a bill to permit cheaper prescription drugs in Canada for sale in the US, Pfizer attempted to change the rules of the game and demand Canadian pharmacies to order directly from Pfizer rather than wholesalers in order to dominate the market and interrupt the supply chain. Pfizer’s track record for fines and lawsuits for violation of its drug safety profiles and ethical marketing are equally damning. In 2009, it was fined $2.3 billion for what was then the largest healthcare felony settlement in US pharmaceutical history for illegally promoting its drugs, including its painkiller Bextra. $1.2 billion was just for the criminal fine; at the time, this was the largest ever imposed in the US for any issue. In 2011, it was found guilty of racketeering charges for illegally marketing its anticonvulsant drug Neurontin and paid $142 million. Three years later Pfizer was fined $430 million to settle criminal charges for bribing doctors to promote and prescribe the same drug. Nor should we ignore Pfizer’s dreadful environmental record: 1971 - Long time illegal dumping of a million gallons of industrial waste annually from its Groton plant into the Long Island Sound; 1991 - A $3.1 million fine for refusing to install pollution control equipment in its Delaware River plant 1994 – A $1.5 million fine for illegal dumping at a toxic waste site in Rhode Island 2003 – Paid a $700 million settlement for dumping PCBs in Anniston, Alabama. Now, we are facing the widespread distribution of Pfizer’s experimental mRNA Covid-19 vaccine wherein the trials to determine its level of safety and efficacy are still underway. It is still too early to make any determination of Pfizer having been engaged in any nefarious activities to get its vaccine rushed to the public. Impropriety and medical negligence so far lies on our government’s shoulders and our bought-off corporate media. Federal health agencies simply ignored their regulatory obligations and gave the vaccine a green light prematurely. Nevertheless, reports of injuries and deaths continue to mount and we will not have any sense of the full cost to human life and suffering from vaccine injuries for a while. In the meantime, China has suspended the mRNA vaccine after a flurry of deaths among Norwegian elderly. The Gibraltar Chronicle reported the deaths of 13 people within two days of receiving Pfizer’s vaccine and that number has risen to over 50 on the tiny island. Hundreds of vaccinated Israelis are still coming down with SARS-CoV2 infections after vaccination. The highly prestigious journal Science reported the growing concerns over the Pfizer vaccine’s polyethylene glycol nanoparticle and its relationship to the growing number of rare but serious allergic reactions and cases of anaphylaxis. And in a briefing document released by the CDC’s Vaccines and Related Biological Products Advisory Committee gave warning that the Pfizer vaccine trials give indication of unusual and unexpected antibody responses, cytokine storms and pathogenic priming that give rise to critical illness and death. Therefore there is no evidence whatsoever that Pfizer’s Covid-19 vaccine can scientifically and consensually be ruled as safe. But as we have observed from Pfizer’s litany of criminal activities above, safety and effectiveness of a drug or product has never been a priority in the company’s executive office. All told, these examples of Pfizer's culture of greed, deception, political maneuvering and mafia-like tactics has collectively injured countless people. Pfizer is a global corporation. Its drugs, and now its Covid-19 vaccine are marketed globally. To better understand Pfizer, the company should be perceived foremost as a cash cow for Wall Street. Its prime directive is selling drugs; its history of misdemeanors and crimes should indicate the company holds no integrity or medical ethics with a sincere commitment to prevent and treat disease. For firms such as Pfizer, injuries and deaths are the necessary collateral damage of getting poorly tested products on the market and as fast as possible. In our opinion, a black box warning should be slapped on the Pfizer logo. And should we trust such a company with the potential to vaccinate an enormous percent of the world population with an experimental vaccine?
Join our email list here: http://thefuturegen.com Remember to Rate, Review and Subscribe on iTunes and Follow us on Spotify Follow us on Instagram: @futuregenpodcast In this episode, Gwen Strickland tells a powerful story of her journey into motherhood and reveals her gut wrenching experience after her son was injured by multiple vaccines mandated by the CDC. She highlights how a majority of parents do the right thing by trusting their doctors and government as pro-vaccine parents and unfortunately, for more than we are allowed to know about, knowingly or unknowingly pay the consequences. Gwen graduated from Cal Poly San Luis Obispo with a degree in Finance and Economics, and has spent the past 11 years working for a large, publicly traded engineering firm specializing in energy efficiency and sustainability. Motherhood propelled her into the world of medical freedom and vaccine safety after her son sustained several adverse reactions in his first four months of life from the Vitamin K, Prevnar 13, and Hib vaccines. Gwen's passion is now advocating for medical freedom for all as she navigates the National Vaccine Court for her son, Andy. ___________________________________ Stay Connected with the Gwen: Watch Andy’s Movie here: https://vimeo.com/422441392 To contact Gwen, please reach out to the Future Generations Podcast. Stay Connected with the Future Generations Podcast: Join our email list here: http://thefuturegen.com Instagram: @futuregenpodcast, @thefuturegensd and @drstantonhom Facebook: Future Generations Podcast and Future Generations | Clinic of Chiropractic Website: Future Generations | Clinic of Chiropractic Remember to Rate, Review and Subscribe on iTunes and Follow us on Spotify!
Episode 20: Baby BluesThe sun rises over the San Joaquin Valley, California, today is Jul 17, 2020.It feels good to talk about prevention when an effective and safe vaccine is actually available! This is the case for the Pneumococcal Conjugate Vaccine 13 (PCV13 or Prevnar 13®). In November 2019, the CDC issued an update on PCV13 vaccination. PCV13 vaccination for ALL immunocompetent adults 65 years and older is NOT recommended. Instead, it is recommended to make a shared decision when these patients do NOT have an immunocompromising condition, CSF leak, or cochlear implant, and have not previously received PCV13. Some candidates for PCV13 include patients residing in areas with low pediatric PCV13 uptake; those traveling to settings with no pediatric PCV13 program; those with chronic heart, lung, and/or liver disease, diabetes, or alcoholism; and those who smoke. PCV13 is still recommended in a series with Pneumovax® (PPSV23) for all adults 19 years and older (including those 65 years and older) with immunocompromising conditions, CSF leaks, or cochlear implants. A single dose of Pneumovax® for ALL adults 65 years and older is still recommended (1,2).____________________________“Perfection is not attainable, but if we chase perfection we can catch excellence.” –Vince LombardiPerfection is a very complex concept. Have you seen a surgery that was performed perfectly? I have. Believe it or not, there are perfect surgeries. Some musicians can play a song perfectly. I think perfection in some areas may be attainable. Another example, I think a person can be perfectly punctual for a time. That’s perfection. However, in most cases, perfection may not be attainable, but we should at least aim for excellence. And today, we have a resident who is in her pursuit of excellence, she is doing very good in her residency. Her voice may be familiar to you because she has recorded many of our introductions, and people have loved her voice. Welcome Dr Der Mugrdechian. Question Number 1: Who are you? My name is Alyssa Der Mugrdechian, I am a 2nd-year resident in the Rio Bravo Family Medicine Program here in Bakersfield. I am a native to the Central Valley having grown up in Fresno, California. I am of Armenian descent and my family settled in California after surviving the Armenian Genocide in 1915. Coming from a family of mostly educators, I am the first to pursue Medicine. I went to UC Irvine for undergrad and majored in Biological Sciences, and my journey to becoming an MD took me to Ross University on the beautiful island of Dominica. Though I have traveled a lot during my schooling, I am happy to have the opportunity to have returned to the Central Valley to complete my residency training in an underserved community close to my family and friends. For fun, I like to draw/paint, I also enjoy cooking, traveling, going to the beach and going to any Disney park as often as possible. Question number 2: What did you learn this week? This month my rotation is Gynecology. I am generally seeing patients for gynecologic issues, OB follow ups and routine post-partum visits. During these appointments, a very important question that can often be overlooked is whether the patient is coping with post-partum depression. Furthermore, another important distinction to make is if it is in fact major depression vs. baby blues. Post-partum Depression (PPD) The post-partum period can encompass the first 12 months after giving birth, however there’s no set length that’s been agreed upon. Major depression is not confined to the post-partum stage, it can also arise during pregnancy. Factors that increase risk of developing Post-Partum Depression (PPD):Antenatal depressive symptomsHistory of Major Depressive DisorderPrevious Post-Partum Depression Other factors to take into consideration are home life, socioeconomic factors, previous or current abusive relationships/situations. Edinburgh Postnatal Depression scale The EPDS is a screening tool for postpartum depression. It consists of 10 questions. The test can usually be completed in less than 5 minutes. Responses are scored 0, 1, 2, or 3 according to increased severity of the symptom. Some items are reverse scored (i.e., 3, 2, 1, and 0). You add scores of each question to get a total score. Cut-off scores range from 9 to 13 points. It requires clinical judgment to determine the right timing for referral. For example, if a woman scores 9 or indicating any suicidal ideation, she most likely would benefit from immediate referral. “In women without a history of postpartum major depression, a score above 12 has a sensitivity of 86 percent and specificity of 78 percent for postpartum major depression. You can find the hand out at the end of this document.Other screening methods include PHQ-9, and diagnosis is based on DSM-5. Distinguishing Between “Baby Blues” and Postpartum Major DepressionCHARACTERISTICBABY BLUESPOSTPARTUM MAJOR DEPRESSIONDurationLess than 10 daysMore than two weeksOnsetWithin two to three days postpartumOften within first month; may be up to one yearPrevalence80 percent5 to 7 percentSeverityMild dysfunctionModerate to severe dysfunctionSuicidal ideationNot presentMay be present Diagnosis and Treatment Labs can also be considered, including TSH to rule out other causes of depressive symptoms Treatment can include both pharmacologic and non-pharmacologic methods such as psychotherapy (interpersonal, cognitive behavioral therapy) Selective serotonin reuptake inhibitors — SSRIs are widely prescribed in lactating women. Breastfeeding should not be discouraged during treatment with SSRIs.DRUGSTARTING DOSAGEUSUAL TREATMENT DOSAGEMAXIMAL DOSAGEADVERSE EFFECTSSelective serotonin reuptake inhibitorsCitalopram (Celexa)10 mg20 to 40 mg60 mgHeadache, nausea, diarrhea, sedation, insomnia, tremor, nervousness, loss of libido, delayed orgasmEscitalopram (Lexapro)5 mg10 to 20 mg20 mgFluoxetine (Prozac)10 mg20 to 40 mg80 mgParoxetine (Paxil)10 mg20 to 40 mg50 mgSertraline (Zoloft)25 mg50 to 100 mg200 mgSerotonin-norepinephrine reuptake inhibitorsDesvenlafaxine, extended release (Pristiq)50 mg50 mg100 mgHeadache, nausea, diarrhea, sedation, insomnia, tremor, nervousness, loss of libido, delayed orgasm, sustained hypertensionDuloxetine (Cymbalta)20 mg30 to 60 mg60 mgSame as selective serotonin reuptake inhibitorsVenlafaxine, extended release (Effexor XR)37.5 mg75 to 300 mg300 mgSame as desvenlafaxine Question number 3: Why is this knowledge important for you and your patients? Sometimes patients aren’t willing or open to discussing this topic. In other cases, it may not even be touched upon by providers following up with the patients. But especially with everything going on this year with the pandemic, mental health is vital to a patient’s overall well-being. It also affects maternal functioning, and ultimately the well-being of the child It can lead to lack of breastfeeding, lack of maternal-infant bonding, problems with abnormal child development, problems with infants sleeping properly and also receiving the proper vaccinations. Suicide can also occur, however this rate is very low in the post-partum period Question number 4: How did you get that knowledge?I got interested in the topic because of the patients I have seen in clinic. I consulted reliable sources such as UpToDate, our day-to-day companion in clinic; American Academy of Family Physician; and the United States Preventive Services Task Force, which is our main source of preventive services offered in Family Medicine. Question number 5: Where did you get the information from?An article by Dr Viguera about Postpartum depression in UpToDate, updated on 11/20/2018. I also consulted an article about safe infant exposure to antidepressants in UpToDate. AAFP has a very good source of information about Postpartum depression. See details below. Edinburgh Postnatal Depression ScaleEdinburgh Postnatal Depression Scale. © 1987 The Royal College of Psychiatrists. The Edinbugh Postnatal Depression Scale may be photocopied by individual researchers or clinicians for their own use without seeking permission from the publishers. The scale must be copied in full and all copies must acknowledge the following source: Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry. 1987;150:782–786. Written permission must be obtained from the Royal College of Psychiatrists for copying and distribution to others or for republication (in print, online or by any other medium). Translations of the scale, and guidance as to its use, may be found in Cox JL, Holden J. Perinatal Mental Health: A Guide to the Edinburgh Postnatal Depression Scale. London: Gaskell; 2003. Speaking Medical: Borborygmusby Max Uschuk, MS4 We all have been in a silent exam and your stomach decides to demonstrate the sound of a humpback whale mating call. That’s borborygmus. What is borborygmus besides an interesting word to say? Technically speaking it is peristaltic movement of gas and fluid through the intestines causing an audible sound that is loud enough to be heard by the naked ear. When someone says their stomach is growling or rumbling, that is borborygmus or borborygmi (plural), not to be confused with bowel sound or peristaltic sounds which require a stethoscope to be heard. Is it medically pertinent? Many things can cause borborygmus. An empty stomach around 2 hours post prandial starts to signal the brain that it is fasting, it triggers peristaltic waves every 90-230 min, and contents are moved through the intestines and function to inhibit migration of bacteria from the large intestine to the small intestine. This movement can cause borborygmus. When someone swallows air while talking, eating or drinking it can increase borborygmus. Incomplete digestion of foods such as milk, gluten, fruits and vegetables, bean, legumes, and high fiber foods can increase borborygmus. Now, this can be normal but when paired with bloating, pain, diarrhea or constipation it can be indicative of a pathological process. Some pathologies such as celiac disease, colitis due to infection or necrotizing colitis, diverticulitis, irritable bowel syndrome, carcinoid syndrome or basically anything that really irritates the intestines can cause borborygmus. From the Practical Medicine Series; General Surgery, “the presence of stormy peristalsis or borborygmus in the absence of fever may be considered pathognomonic to intestinal obstruction as it never occurs in adynamic ileus” Thank you for listening and I hope you get to use the word borborygmus sometime soon. ____________________________Espanish Por Favor: Spanish Last Namesby Dr Claudia Carranza“Hola, me llamo Fernando Hernandez Guerrero Fernandez Guerrero.”That’s a fictional name from Fuller House, but sometimes that’s how Hispanic names sound like to English speakers. Hi, this is Dr Carranza in our section Espanish por favor, today instead of bringing you a word of the week I wanted to discuss a topic with everyone. It’s the topic of last names! In the States, people usually have one last name, unless once married they chose to hyphenate their last name. Well, in the Hispanic culture we usually have 2 last names. The last names we have are first, our father’s last name, and our second, our mother’s last name. So, for example, my name is Claudia Carranza, but the name given to me at birth was: Claudia Roxana Carranza Guzman. I don’t think I have ever met anyone in Peru (where I’m from) that only had one last name. Dr Arreaza brought up an interesting point, which is what if people in Latin American cultures have one last name? I’ll let him expand on this topic. Dr Arreaza: Having only one last name may have a negative social connotation. When someone has one last name in Venezuela it usually means that you are a “natural son”, or illegitimate, or born from a single mother. Dr Carranza: In Peru, at least what I saw growing up, if a child only had one parent then they took the full first and second last name of that parent. So, guys when you meet a Hispanic patient with two last names, remember that their 1st last name is the one they will usually go by, not the second. So, for my name Claudia Roxana Carranza Guzman, you would call me: Claudia Carranza, not Claudia Guzman. Hope this helps when you are trying to figure out what last name to use when you see a patient or have a coworker with 2 last names!____________________________For your Sanity: by Steven Saito and Tana ParkerDoctor: I have bad news, and very bad news.Patient: What's the bad news?Doctor: You only have 24-hours to livePatient: And the really bad news?Doctor: I’ve been trying to contact you since yesterday._______________________________Now we conclude our episode number 20 “Baby Blues”. Dr Der Mugrdechian reminded us to screen for post-partum depression using the Edinburg Postnatal Depression Scale and make sure it is not “baby blues.” Max taught us the word borborygmus, just a fancy way to say “very loud stomach growling,” and Dr Carranza explained that the name you see at the end of a looooong Spanish name may not be the actual last name. The actual last name is the name before the last, I know it may be confusing, but it’s OK to ask your patients their preferred last name. This is the end of Rio Bravo qWeek. We say good bye from Bakersfield, a special place in the beautiful Central Valley of California, United States, a land where growing is happening everywhere.If you have any feedback about this podcast, contact us by email RBresidency@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. This podcast was created with educational purposes only. Visit your primary care physician for additional medical advice. Our podcast team for this episode is Hector Arreaza, Alyssa Der Mugrdechian, Claudia Carranza, Lisa Manzanares, and Max Uschuk (pronounced Use-Chuck). Audio edition: Suraj Amrutia. See you soon! _____________________References:Use of 13-Valent Pneumococcal Conjugate Vaccine and 23-Valent Pneumococcal Polysaccharide Vaccine Among Adults Aged ≥65 Years: Updated Recommendations of the Advisory Committee on Immunization Practices, Weekly, November 22, 2019 / 68(46);1069–1075, https://www.cdc.gov/mmwr/volumes/68/wr/mm6846a5.htm#T1_downShared Decision-Making for Administering PCV13 in Older Adults, AMIT A. SHAH, MD; MARK R. WALLACE, MD; and HEATHER FIELDS, MD, Mayo Clinic, Scottsdale, Arizona, Am Fam Physician. 2020 Feb 1;101(3):134-135. https://www.aafp.org/afp/2020/0201/p134.html Viguera, Adele MD. “Postpartum unipolar major depression: Epidemiology, clinical features, assessment, and diagnosis” UptoDate. Last updated 11/20/2018. Mary C Kimmel, MD, Samantha Meltzer-Brody, MD, MPH, “Safety of infant exposure to antidepressants and benzodiazepines through breastfeeding” UptoDate. Last updated 11/10/2019. KATHRYN P. HIRST, MD, and CHRISTINE Y. MOUTIER, MD, University of California, San Diego, School of Medicine, La Jolla, California. “Postpartum Major Depression”, Am Fam Physician. 2010 Oct 15;82(8):926-933. https://www.aafp.org/afp/2010/1015/p926.html
Contact Sunlighten Saunas for their Special Listener Sale during the month of June for Father's Day! Call 877-292-0020 Check out the supplements Ashley James recommends: takeyoursupplements.com Magnesium Soak: Use coupon code LTH at Livingthegoodlifenaturally.com IT'S HERE! Learntruehealth.com/homekitchen Use coupon code LTH for the listener discount! Check out IIN and get a free module: LearnTrueHealth.com/coaching Dr. Judy Mikovits’ Plague of Corruption https://www.learntruehealth.com/dr-judy-mikovits-plague-of-corruption Highlights: Genetically modified foods cause different diseases such as cancer Vaccines are manufactured as one size fits all and are injuring some people Vaccines contaminated with lots of viruses Wearing a mask causes oxidative stress after some time Is wearing a mask necessary to prevent you from getting COVID-19? Or is it doing more harm to the body than good? In this episode, Dr. Judy Mikovits uncovers some things that the mainstream media is not reporting. She talks about vaccinations, coronavirus, and wearing a mask. She also enumerates the things we should be doing to have a healthy immune system. [00:00:00] Ashley James: Welcome to the Learn True Health podcast. I’m your host, Ashley James. This is episode 436. I am so excited for today’s guest. We have with us, for me, this is like having a celebrity on the show, Dr. Judy Mikovits. I heard your interview with Robyn Openshaw, whom I’ve had on the show before. Then I started hearing you pop up in other places and many other alternative health interviews. The information you have to share is amazing, but what I’ve been equally as surprised is the pushback from the mainstream media, how they are trying to discredit you. You have such a strong background in science, and they’re trying to discredit you. That makes me feel like you’re on to something. They don’t want people to know your information. You came out with a book called Plague: One Scientist’s Intrepid Search for the Truth about Human Retroviruses and Chronic Fatigue Syndrome and that is fascinating. So many people suffer from chronic fatigue syndrome that would love to know more about how they could support their body’s ability to heal itself and come back into balance. Recently, in April, you released with your co-author Plague of Corruption: Restoring Faith in the Promise of Science. I’d love to talk about both your books today, and I’d also love to talk about wearing masks, about the coronavirus, and also about the background that you have that educates you in your interpretation of the current events that are going on. Welcome to the show. [00:01:47] Dr. Judy Mikovits: Thanks so much, Ashley. It’s a delight to be here. [00:01:51] Ashley James: Absolutely, yes. [00:01:52] Dr. Judy Mikovits: In fact, our first book Plague, Kent Heckenlively co-authored that with me, it actually came out in November of 2014 and the paperback came out in 2017. What’s interesting about that is the paperback has new material in the front of the look all about what I didn’t know about the Plague of Corruption surrounding what happened to me about the events in Plague. We called it Plague because we associated a new family of AIDS-like viruses with contagious retroviruses from mice, not only with chronic fatigue syndrome. After our first paper was published about chronic fatigue syndrome, it became clear that these viruses, there was a large family of viruses, not only from mice, but from monkeys and other things that had heavily contaminated the blood supply then were associated with not only chronic fatigue syndrome but cancers, autism, autoimmune disease, Lou Gehrig’s disease, and multiple sclerosis—just a nightmare. [00:03:12] Ashley James: Oh my goodness. That is revolutionary to be able to see that viruses could be the contributor of or the trigger for those illnesses. Why isn’t this more widespread? Why isn’t this information being more widely accepted? [00:03:30] Dr. Judy Mikovits: Obviously, the problem is that the government caused it. The paper was celebrated when it came out because doctors everywhere saw it because it was published on October 8th in our science paper of the discovery of this new family of human retrovirus. What I should say is we didn’t necessarily discover it, the sequences, parts of those viruses had been described about two, three years earlier in men with an aggressive form of prostate cancer that was really not familial that appeared to be infectious. My background is cancer research, drug development, and immune therapy. That’s what I did at the National Cancer Institute for 22 years including my last job. From 1999 to 2001, before I left to go to industry, was the lab of antiviral drug mechanism. My job, in that job at the National Cancer Institute as a director of an internationally recognized program, was to understand how HIV/AIDS-associated cancers. How to cure them? What were biomarkers? What was driving cancer in some people with HIV like Kaposi sarcoma will remember, brain cancers, some kinds of lung cancers, or leukemia? There were other viruses associated. We learned that Kaposi sarcoma, which ended up being a herpes virus, collaborating with the HIV and so you could target both. We’ve made great strides since 1999 in curing HIV/AIDS-associated, not only malignancies but other diseases such that we now know quite well, we see it on TV every day, you can have HIV and never get AIDS. This was my background that you asked for. It’s experience started with a biochemistry degree from the University of Virginia, started to develop immune therapies. Remember, vaccines are immune therapies. What that means is my entire life’s work is based on the idea, the hypothesis, the fact now that we know is the fact that you can educate the immune system to prevent and treat infectious and chronic diseases including cancer. My first job was to purify type 1 interferon and that interferon was the first immune therapy used. It’s actually, still to this day, a fabulous prevention strategy for even coronaviruses and other retroviruses and would have been a treatment for AIDS. But the Plague of Corruption, the reason we wrote the second book, is what we realized in August of 2014 when our first book was impressed. What I realized when I first met one of my heroes Dr. Brian Hooker who uncovered, who dogged criminal scientist William Thompson of the CDC who admitted their studies were fraud, who admitted they covered up the fact that if you gave vaccines to black boys MMR in that particular study if you gave MMR to black boys before they were three years old, they had a four-fold higher risk of developing autism and even being killed by those vaccines by SIDS. Here in 2020, nobody seems to recognize that for 20 years from 2001 when they covered up the data in a paper that William Thompson was an author on and then they had a date a burning party, this is what Dr. Brian Hooker uncovered. He’s really the hero in all of this because had I never met him on August 31, 2014, we would have never realized that the Plague of Disease is this explosion in cancer and chronic diseases that we see today was in fact caused by heavily contaminated blood supply since the 80s, since the earliest days of HIV/AIDS through vaccines, which all liability had been removed from in 1986. They were heavily contaminated by lots of viruses, not just the family we discovered—mycoplasma, mold, think of chronic Lyme disease, and Borrelia. You don’t get a bull’s-eye, why? Because you injected it, you weren’t infected with it. [00:08:58] Ashley James: I watched the Vaxxed documentary and that’s something I think everyone should watch no matter where they stand on vaccines. I think we need to step back and just be okay with taking in information that may go against our current belief system. If we’re holding so firmly onto our belief system that it becomes dogma, then we blind ourselves to a new truth that may arise. I’m not asking anyone to be in anti-vaxxer or a pro-vaxxer or whatever. I’m just asking people to open their minds enough to let new information in. I wasn’t expecting to actually receive much new information going into watching the documentary Vaxxed, but it absolutely floored me when I learned about what you just talked about where you can look at the numbers and clearly see that African-American children have a huge disadvantage when given the MMR vaccine over other people with different genetics. Genetics come into play. Can you explain that a bit further? How certain people with different genetics are affected by vaccines, and why are we giving the same vaccines to all children across the board if we’re seeing that there’s more damage being done to certain people of genetic makeup? [00:10:31] Dr. Judy Mikovits: There are genetic and epigenetic. That means environmental susceptibilities and that’s one of the saddest parts about the story Vaxxed. I appreciate you saying to watch that because, in fact, there’s a second movie called Vaxxed 2: The People’s Truth. Polly Tommey, who was in the first movie and her son severely injured by a vaccine. He was an African-American. One of the things I should clarify is that white boys had two-fold, a higher fold risk if given the vaccine before a certain age. One of the reasons goes back to those cancer-causing viruses and the susceptibilities for the prostate cancer because what happens is, genetically, we have a lot of different enzymes in our immune systems that degrade RNA viruses. This is what MMR. Those are three different RNA viruses. We inject them in a single shot along with, for a while, mercury but certainly other contaminants, which we’ve uncovered over the last few years since there’s no liability now for 30 years and no safety testing has been done. This is another thing that people don’t realize. Anyway, your detox machinery—your liver, your kidneys, and your immune system—doesn’t fully develop until you’re at least three or four years old. As people think back, I’m 62 years old and I didn’t get a measles vaccine because I had a measles infection. I had the disease and therefore I had immunity from life. I would never, even if exposed, have an issue again. That remains true to this day. In fact, MMR, it’s not only blacks but it’s dark-skinned—Mexican, people around the equator—they have different responses to the pathogens in their environment. They have a single nucleotide difference in one of the key degradation, so it breaks down. It’s an enzyme that when it sees RNA or RNA viruses in the blood, it just acts like a Pac-Man because RNA in the blood is a very bad thing. You want RNA in your nucleus. You don’t [love 00:13:07] your cell and it’s protected by two membranes the nuclear membrane and the cellular membrane. When RNA and DNA, your blueprints for making proteins and regulating all of your gene expression, end up in the blood and in the cytoplasm of your body, it says uh-oh, that’s a danger-associated molecular pattern—remember, I’m a molecular biologist—or a pathogen-associated molecular pattern. It goes and uses different kinds of enzymes that recognize those different patterns and it just chews it all up like a Pac-Man. There’s a single change that makes the enzymes in blacks, Mexicans, and people near the equator have 50% less activity. That is they don’t chew up those RNA viruses as quickly. We don’t really know why. Nobody really knows why. In fact, if those data hadn’t been covered up for political reasons in 2001, we in the Cancer Institute who knew nothing about autism, which was 1 in 10,000 kids and when I graduated from the University of Virginia in 1980. My minor was in children retardation, that kind of thing, for children and looking at those kinds of things to try and understand exactly the questions you’re asking. It was educational. Why are some kids sick, developmental disorders, and things like that? Autism wasn’t even in those books in 1976 to 1980, in our textbooks. What we learn, if we don’t cover up data that reveal inconvenient truth, is we could actually prevent so much injury. That was what was so devastating to me. The realization in 2014 is oh my God, you covered up that those data for 20 years. We didn’t understand why there were differences because we didn’t even understand RNA cells and the immune system or these pathways. New technology, new data, and new opportunities for healing diseases, and understanding the causes. We thought there was no problem with GMOs and it sounds like a good idea. We can feed the world, but in fact, you can’t genetically modify organisms without having them harm other organisms because they are they harm the gene regulation of the entire, whether it be plant or an animal. These are things that are designed by God for a purpose to be used as food. Now we know GMOs can actually contribute and cause cancer and all of the diseases we’re talking about and this is the problem. If all you had to do was wait until black boys were three years old and wait to administer that shot, well nobody administered a single shot anywhere to me until I was five years old. I think I got the oral polio vaccine in kindergarten and of course, we got smallpox, which was then cowpox under the arm. That’s all we got in my life. We got nothing at puberty. We got nothing in 7th grade. We got nothing to go to college. We got nothing at all. I didn’t get another vaccine until I was working with AIDS patients. I was encouraged to get a hepatitis B vaccine, which I did because I was of childbearing age but my boss at the time who was 46 or 50, he said, “No, thanks. I don’t need it. I’m not going to have any more kids. I don’t need to worry about these things.” It’s very interesting how our world has changed. This is why I really appreciate you encouraging people to watch these movies and read these books. There is no such thing as an anti-vaxxer. Every one that is called an anti-vaxxer now is an ex-vaxxer because they were injured and the government didn’t take care of them as the National Vaccine Injury Compensation Program of 1986. What that did was remove all liability from pharmaceutical manufacturers, pharmaceutical companies, from doctors, and from anybody giving vaccine saying hey, we don’t understand those genetic and epigenetic susceptibilities. Vaccines are unavoidably unsafe, so for the greater good, we’re going to remove all liability. But the government is going to compensate the injured. That program has been so corrupted over the last 30 years. As a part of that program, the government—the HHS, NIH, NIAID, we hear National Institute of Allergy and Infectious Disease—they were told it was their job to make them safe. To do the safety testing, to see if the combinations, to see if the age ranges, and to do the safety studies in the appropriate populations you were giving the vaccines. We learned only last year by dog at work by Bobby Kennedy in the Children’s Health Defense organization and Del Bigtree of the ICAN decide, that not a single safety test has been done. Not a single safety test or efficacy test has been done. The vaccines aren’t looked at in any way. Every year they roll out a flu vaccine. They don’t look at it at all. They don’t do any safety testing. They don’t do any testing to see if these mouse viruses, monkey viruses, or coronaviruses. The flu vaccine they rolled out on Italy in 2019 had four different live attenuated that means weakened strain. Live attenuated, that means they make a virus, that means you make a virus, that means you’re being injected with four different strains of influenza, and they grow they manufacture the little virus factory are dog kidney cells. Dog kidney cells have lots of coronaviruses. Dogs, all animals, even a flu vaccine grown in chicken eggs have coronaviruses. Here, we don’t look at them at all. We’re talking about a coronavirus that somehow escaped and one person traveled around the globe and hit 190 countries overnight in what really appears to be what drove this plandemic, and I’m just going to keep calling it that because it has little to do with an infectious virus that we’re exposed to by the natural route. It probably has everything to do with a coronavirus, a novel engineered virus from Wuhan, China as we all clearly know now that has in the cell line it was grown in. It was the Vero E6 kidney cells. They were manufacturing growing that virus up in large stocks and shipping it around the world to other investigators in Switzerland, in North Carolina, in Wuhan, and at Fort Detrick. All of this is funded by Tony Fauci and NIAID. Here, you’re manufacturing that in monkey kidney cells. Well, that’s where we get HIV. That’s simian immune deficiency virus is the ancestor of humans. How do animal viruses jump into humans? That’s the big question. Our studies in 2011 said the most likely way mouse cancer-causing and neuro-immune disease-causing retrovirus contagious jumped into humans was by vaccines. Because we’re injecting them. You don’t need to be exposed if you’ve injected them. This is the problem. Nobody’s shown one piece of evidence that said the flu vaccines, particularly, in Italy and here in the United States that the program, over the last four years with contaminated while they were doing that research. Remember, they were doing that research in the same facilities where they’re manufacturing vaccines— polio vaccines. Vero monkey kidney cells are what we grow polio vaccines in. MMR and live attenuated viral vaccines hepatitis, chickenpox, these vaccines are grown in animal tissue. What our book, Plague of Corruption, raised the horrible question. The whole thing about mixing animal tissues and injecting them into immune incompetent, meaning you’re compromised because you’re very young and you haven’t developed that machinery as I just said. You’re compromised because you’re very old and your immune system has been cleaning up these things forever and it gets overwhelmed. What are we doing is we’re taking the most vulnerable parts of our society and we’re injecting them with animal tissues and we’re driving these pandemics literally around the world. This knowledge, all while we were doing these flu vaccines in 2012 through 2018, we were doing these studies with China in the US, in China, at Harvard, and in Switzerland and sending these cell lines, these little virus factories, containing these coronaviruses, these bat viruses, and these monkey viruses and they were recombining. Things got unleashed in contaminated water supplies, feces of animals. We don’t realize we don’t only vaccinate humans, we vaccinate our food, we vaccinate our animals, we vaccinate our herds, and their viromes then wake up and can infect humans in the form of GMOs like bovine growth hormone. There’s a whole chapter in our book about my work in pharmaceuticals on the GMOs and how they were damaging human cells. It’s just the explosion of disease is because this has been covered up now for at least two decades. [00:24:27] Ashley James: This cover-up must be global. I’m just thinking back to what you said about when looking at the results with those people of color that when they’re vaccinated with the MMR before the age of three, if you look at the raw data, people can see that statistically, they suffer a greater vaccine injury like autism than those who are not from the equator or they’re genetic, their ancestors aren’t from the equator or near the equator. That’s been covered up for 20 years. My question was going to be like who in the United States covered it up? But it’s not just the United States. It’s every country around the world has been using these vaccines and every country must also have been covering it up. That’s just as a global cover-up. [00:25:29] Dr. Judy Mikovits: Think about what we’re doing right now. The WHO, sure it is a global cover-up. There have been groups in Sweden and in Somalia with the Gardasil injury and this fraud by Merck. These immune mechanisms don’t just go that way. We see a lot of people in the UK, Ireland, and Sweden because they don’t get a lot of sunlight. Vitamin D receptors are quite different, vitamin D signaling is quite different in people from the equator and people in Minnesota or Sweden because you don’t get a lot of sunlight. Vitamin D receptors have to act like amplifiers if you don’t get much sunlight because that’s how we convert vitamin D into the active form that controls more than 300 immune reactions and counting. Yet if you’re near the equator where you get a lot of sun, your vitamin D receptors have to act as resistors. One is amplifiers, one resistor. One molecule looks like 1000 if your genetics are from certain countries, and one molecule looks like 1/1000 if you’re from near the equator. These are things we just simply don’t know about. What we do with vaccines is say one size fits all. It doesn’t fit all and we give the same. Why would we give we didn’t develop? This is always the royal we. The guy who discovered and made the hepatitis B vaccine, a scientist doctor, was horrified when he learned we gave it to hours old babies. That’s not what he intended that work to be done for. This is the big problem is the scientists like me, the rank and file, we’re doing this to cure cancer. My whole life was to use natural products, use plants, educate the immune system, eat healthily, don’t get yourself any toxins, stay out of the way, and we’ll save everything. I helped work on those immune therapies. I developed those things. I encouraged my own family to get the Gardasil shot because we thought they’d done the right studies. We thought they’d done a saline control. They didn’t do anything at all. Worse than that, they covered up the damage done by these things. Yes, it’s a worldwide global—most of the vaccine manufacturers aren’t in the US. They’re in Europe, they’re in China. Think about the garbage that’s coming into this country and yet nobody ever looks at what’s being injected and forced into your arm or you don’t get an education. Now they hit the big detonates switch. I believe it’s because the royal we, these groups, we’ve been fighting for decades. Brian Hooker spent 15 years dogging William Thompson—tell the truth, tell the truth. How can anybody call me an anti-vaxxer? Really? We discovered half of the immune system in the therapies. We saved millions from HIV by our discoveries on how HIV can cause disease. We have TV commercials for HIV prophylaxis. That means pre-exposure prophylaxis. You can live your lifestyle any way you want and should you come in contact with somebody with HIV, we have therapies, we have prevention strategies. We have those same prevention strategies for coronavirus like 70-year old drug hydroxychloroquine, the anti-malarial drugs that we know low dose is fabulous for anti-inflammatory diseases. Coronaviruses don’t hurt you by themselves. It’s the inflammation, it’s the fire. We know those mechanisms. That’s what we’ve been doing. That’s what I’ve been doing for 40 years and probably closer to 50 years because I started doing it when I was 12 years old. I never looked back from junior high school when my grandfather died of lung cancer. I’m thinking, why don’t we save somebody. Cancer was a closet disease. Okay, you don’t smoke; okay, you don’t expose yourself to asbestos. Now we learned that they injected in the polio vaccines knowingly from 55-65, gave millions of people simian virus 40, which is lung cancer, mesothelioma, a cancer-causing virus, and many different kinds of cancers. We isolated in 2009 mouse viruses, monkey viruses, and bird gamma retroviruses. In MMR 5, a study was done in 2019 by an independent group called Corvelva in Italy. They showed dozens of human viruses, dozens of horse viruses, and dozens of other viruses. You don’t need an infectious virus if you injected it. This is why I particularly wanted to come onto your show today because if we don’t want to see round two, three, four, or five of your COVIDS, the worst thing any person can do is get a flu shot, a pneumonia shot, or a Prevnar shot. If we get those shots this year if people don’t wake up and they say I’m going to get my shot to prevent—no. When that sign, as we drive by on the highway here in California, says save lives, act responsibly. Yes, act responsibly. Do not get a vaccine. Do not wear a mask. The mask is immune-suppressing you. The mask is causing you to activate your latent, you’re silenced, your immune system has degraded those viruses. You wake them up. You get oxygen-depleted. You make yourself sick. Every one of those viruses goes right through any one of those masks and you’re making people sick and thinking you’re helping them, but most importantly, you’re killing yourself. If you get a flu shot or Prevnar, they give them on the same day and they act like they only gave you the flu shot, Prevnar right now is 23 different microbial antigens with a screamingly heavy dose of microbial upper respiratory infection causing pneumonia, causing antigens with a heavy dose of aluminum. You inject that in one arm, in the other arm you give those live attenuated flu cause that kind of upper respiratory infection, that cough in an immune-compromised person, in somebody, an old person who’s already on all kinds of drugs. We have no idea how much garbage is in those needles. Nobody knows what’s in those needles because nobody’s been allowed to test them, but Corvelva in Italy in 19, in 18 got samples of these vaccines and did the kinds of studies with the technologies and showed how many heavy metals. That stuff is so caustic. They found the metal from the needle in the people’s blood. You could see red blood cells from other animals in the people in the Gardasil shot in the [inaudible 00:33:36] paper of 2017. I can provide these to you so you can post them for all the world to see, but it’s absolutely horrific what’s being done. This is why we need to talk right now and we need to tell everybody to wake up. If you’ve ever had the flu or you’ve ever had the flu vaccine, you’re as protected from getting a bad disease as you’re ever going to get. We know that the coronavirus, even this engineered SARS-CoV-2 with HIV sequences in it from that cell line they grew it in, even with that, most people are healthy. Healthy people don’t spread disease. There’s no such thing as an asymptomatic carrier. Just as you said, yeah, it’s a worldwide effort. If your listeners, watch thehighwire.com with Del Bigtree from last Thursday, you will see the World Health Organization official who said, “Oh, wait a minute, we made a mistake. Oh, yeah, it’s very rare that an asymptomatic person will spread disease so you don’t have to wear the mask. We know that every single thing Fauci says and the Deborah Birx and Robert Redfield, they’ve gone back on and shown to be wrong. Robert Redfield said, “Well, the mask and the distancing, that stopped influenza this year.” No, it didn’t. No, it didn’t. The people that got the flu vaccine and wore the mask died and they called it COVID-19. When you watch those two shows, you’ll watch how the brave nurses and doctors undercover are realizing they’re killing the people in the hospitals. They’re killing them with the protocols that have nothing to do with the coronavirus, with ventilators that have nothing to do with what the person is presenting with. You’re walking and then your relatives can’t see you. They cremate you. They don’t do an autopsy. It’s all a big cover-up. It’s a plandemic and a Plague of Corruption. The single most important thing we can all do to prevent round two is never get another vaccine until they do the studies and they prove everything we’re saying is wrong. That’ll take a few years and then we’ll realize we can regain our health. That’s the only thing. I can guarantee you, I do these cases in vaccine court. The flu vaccine killed far more people this year than the coronavirus, than COVID-19. It’s difficult to sit here as a scientist. Hey, they’ll take this down as soon as I put it up. We’ve offered. I’ve sat here for the last three months and said I’ll talk to anybody, Here, show me the data. What did that WHO official do? See the data keep revealing. It’s not just my data. I don’t do any data. Hey, I lost my job a long time ago. I haven’t worked in a lab in a decade. All you have to do is read the literature. All you have to do is look around. Wait a minute, the WHO stopped hydroxychloroquine based on two fraudulent papers in Lancet. We commissioned fraud and really quickly, a whole bunch of papers come out so you mass prevent this. What about the four decades of research, the OSHA, and the federal regulations that say don’t wear a mask if your oxygen drops from 23%, which is what’s in the air or something close to that to 17%—you do brain damage. That’s 15 minutes in a mask, or if you’re an old person, this is Peggy Hall, thehealthyamerican.org. I’m saying things that your listeners can look up. Lookup The Highwire show. This isn’t me talking. This is all of us doing every we can to save humanity and our way of life. Every measure they’ve made is based on a model that didn’t turn out to work out, and every word I’ve said for four decades is based only on data. I show you the data. I’ve shown you the data in our papers. I’ve heavily referenced, we have heavily referenced both books, not one word from Fauci. Answer it. Don’t take science the journal and say Judy Mikovits is now a bartender because she couldn’t get a job. Yeah, I’m a chemist and yeah, I make a great drink. I’m a Staff Commodore and a volunteer at a yacht club in Ventura, California where I joined in 2000. I was the Commodore in 2006. Yeah, it’s volunteer so I make an occasional drink, but the way it’s spun is Judy Mikovits is the person who never did anything. The data don’t show that. I don’t care what you say about me, just show the data. They won’t show the data and the news will censor everything. Show us. Your audience can think well, wait a minute, she’s right. We never wore a mask before. Why would you immune suppress? Dr. Russell Blaylock, a fabulous clinician, probably a little my age or a little older, wrote a very beautiful paper about all the immune suppression with masks. That very memory immune, CD4 memory response you need to remember you saw a pathogen before that pathogen-associated molecular pattern. That is quickly extinguished with a mask. [00:39:29] Ashley James: Can you explain that? Can you just dive into that a little bit and explain it? Explain why wearing a mask is harmful? You’ve talked about the lower oxygen, but how does it actually negatively affect the immune system? [00:39:43] Dr. Judy Mikovits: Because the immune system, we’re meant to live with it at a certain level of oxygen. Oxidative stress, we have lots of antioxidants in healing plants, right? When inflammation, white blood cells go off in inflammation because there’s a problem, it’s like sending fire trucks to the fire. When you’re inflamed, when you’ve seen a toxin or a pathogen, your white blood cells wake up and you go to the site of tissue injury. The major antioxidant intracellularly in between your nucleus and your cellular membrane is glutathione. Glutathione is quickly taken up when you aren’t breathing enough oxygen because you’ve created oxidative stress so now you need more of your most potent antioxidant glutathione. You make that out of three amino acids and glycine is the critical one because glyphosate, which is Roundup, now all our food is poisoned with glyphosate. We don’t get as much healthy building blocks of those three amino acids to make up glutathione for your cells. You’re crippling your antioxidant in your cells and all of a sudden, pathogens get in. If you don’t get vitamin D and vitamin C those are your extracellular and those stimulates. When you’re wearing a mask you’re depleting your oxygen, your alarm signal goes off and says oxidative stress. You’ll get dizzy, you’ll get migraines. What is pain? Pain is inflammation. Pain is dysregulation of your endocannabinoid in your immune system so it says hey we got a really big problem over here, send out more troops. You deplete your CD4 T-cells. I’m telling you the way I hope you can see it visually and not as a chemist. You deplete the CD4 T-cells because you exhaust them. You say I’m under siege. No, you’re not under siege, you’re just not breathing air. It goes into something called lactic acidosis so your mitochondria take oxygen in the respiratory chain through the eight different complexes in your mitochondria. The powerhouses in the cytoplasm cell that’s what makes ATP, that’s what makes energy. You’re getting less if you’re not breathing air. If you’re compromised anyway because you’re inflamed because you’ve gotten a vaccine, vaccines are made to inflame. Turn on the immune system to fight the invader they’re injecting, the antigen they’re injecting. That gives you a memory response. If you’re compromised you can’t clear it, you can’t make enough as we’ve been talking. We’re not plants. We don’t do photosynthesis for energy. There are many, many more than one mechanism, but the point with OSHA’s safeguarding and Peggy Hall and thehealthyamerican.org will show this in Orange County, she won. She won the OSHA federal safeguards—says if you wear a mask, regardless of who you are, your oxygen blood drops below 17. You can put a little measuring thing in there and everybody’s going to be different. My husband and I have lung diseases that he’s had for years and I was born with. That’s why my voice sounds like this. I have a deviated septum, which means I can’t breathe through my nose at all. If you drop below 17, the little alarm will go off and that’s doing brain damage. That’s going to make you dizzy. If you wear a mask sitting in a closed car, what exactly are you going to get sitting in a closed car with the person you shared spit with for 20 years? That doesn’t make any sense. That’s like driving drunk because you’ve inflamed yourself. It’s called acidosis at a point 15, 20 minutes, you’re dizzy, you’re confused, you go over the lane. You’re already 90-year-old going over the lane. I know my husband’s 82, he drives badly. It’s like really? If you have a car crash, whose fault is it? Is it the government or did you die of COVID-19? No, you don’t wear a mask in a car with all the windows rolled up getting pollution from the car. It’s sitting in traffic in LA in the heat or think of even a healthy young man. We know people and they talk to me because I’m me, but we know people who work in your local Lowe’s store. They climb up ladders all day long and they wear that mask. They get a headache and by the time they get home at night, they’re in pain, they feel horrible, they have migraines, they can’t breathe, and they’re exhausted. The next day they go back to work and they fall off the ladder. I can’t even imagine putting a construction worker at the top of a ladder on a building and leaving him in the hot sun here in California. No, this has nothing to do with human health. You don’t walk down a beach. You breathe air. You ground your feet in the soil, in the microbe, all those nice microbial sequences in the soil from things that naturally degrade—marine biomes, plants naturally degrade. That’s natural immune-boosting through your skin, your immune system. You don’t hide in your house with Clorox, those spray cleaners. I sat at a coffee shop where all the employees this morning had masks on because they’re required by law. In comes the Terminix guy to spray. I’m like oh no. I just pointed to a couple of doctors who were with me and I pointed at him. I could cry looking at this. I see people spraying baseball stadiums to let everybody in and cleaning, cleaning, cleaning. What’s in those toxic cleaners? You’re going to concentrate that on your mask. That’s going to further inflame your throat. People ask me, do you wear a mask? Yeah, I wore masks in my life. I wore masks in 2017 when I lived in Ventura, California, as I do now, and the Thomas fires. The smoke was so heavy that you couldn’t breathe for days. Yeah, we had lung diseases and we got those exact N95 masks to stop the smoke. You stop other things from damaging your lungs. People say well they wear them in China. Yeah, it’s heavily polluted. Yeah, they wear them in China. Places where they’re heavily polluted. Places where they’re heavily concentrated. There are a lot of people with a lot of different things in pollution. It’s not drive yourself and drive the inflammation in your throat. I couldn’t wear a mask 10 seconds before that ringer would go off and I don’t wear one. I didn’t wear one. I worked for 25 years, in fact, it’s probably closer to 40 years, isolating those very retroviruses I mentioned. Those cancer-causing and AIDS-causing viruses from sick people. We wear masks in surgery situations to keep everything sterile, but you don’t wear them in the hallways of the hospital. You don’t compromise your own immune system. I never wore a mask working with a patient ever and I isolated HIV. I never got it either because the last thing I wanted to do was immune suppress myself. [00:47:42] Ashley James: I felt like people were being a little sensitive when it came to masks. I kind of was like oh, masks aren’t a problem. They’re not going to lower my oxygen levels. I had this little medical mask. The kind that like dental hygienists would wear. I used it to go into Whole Foods. I’ve only been wearing it quickly, get some groceries, get out because they have signs everywhere. The times I went to the grocery store and refused to mask I would just get dirty looks the whole time. I don’t need that. I’m going to just blend into the crowd, wear a mask, and get out. The last time I did, this was a few weeks ago, I nearly collapsed. It was really scary because I didn’t really believe that a mask could make me faint. I’m not sick, I’m a healthy person. But standing in line, I’ve been wearing it for maybe 15 minutes, I started to blackout. I couldn’t see anymore. I was fainting, basically. I tore the mask off and it took me hours to recover. My heart was racing, I was so terrified. I was just absolutely terrified. I can’t imagine what the workers who are being forced to wear a mask eight, nine hours a day are going through. Now to hear what you say that it really does lower the oxygen levels in our blood and cause inflammation, cause the body to have to eat up our glutathione, which is a very costly thing for the body to make, especially if someone’s nutrient-deficient like selenium, for example, recycles the body’s glutathione. Most people are deficient in that mineral. Someone who may be nutrient to deplete in certain nutrients, it would cause them quickly to have ill health even further. Right now, we’re so focused on keeping the immune system healthy. If we watch the mainstream media it’s like Armageddon out there. If we follow the mainstream media we are terrified for our lives. Then we listen to doctors and PhDs like yourself who have been in this world from a scientist’s perspective for years and you’re saying masks are harmful in terms of how they’re being recommended to be used right now, that it is actually not helping us, and that we should be focusing on making sure we have our vitamin D and our vitamin C, making sure we’re eating organic non-GMO foods, making sure we’re getting out in the sunlight and fresh air. [00:50:28] Dr. Judy Mikovits: Correct. [00:50:30] Ashley James: What other things can we do to boost our immune system and stay healthy from the scientist’s perspective, from your perspective since you have studied the immune system for so many years? [00:50:43] Dr. Judy Mikovits: A critical thing you just mentioned—minerals. We’re so mineral-depleted in zinc, magnesium, and manganese. Our soil has been heavily depleted. It’s contaminated with glyphosate. What you want to do more than anything is I would encourage a mineral supplement. I use products from different places but my mineral supplements are Quinton minerals and one other, I forget the name of them. You just get a really good, and I don’t just mean magnesium or manganese because you throw the balance of all of them. You want 97 different minerals mixed together just like nature in seawater. You want iodine with kelp because radiation is a huge issue in our inner health anyway, so all of these things are contributing to us being sicker, being susceptible, and being immune suppressed immune-compromised because our Earth’s been getting more polluted. With kelp that you can buy in your health food store. Things like liver bitters and detox for your liver. Keep your liver healthy, keep your kidneys healthy, so get a good mineral supplement. I’m looking through here to see what I usually take. The best precursor to glutathione supplement I know is called ProImmune. That’s Ted Fogarty MD product HBOT, a hyperbaric oxygen therapy. Saunas to detox. Detox all you can. You mentioned a lot of simple things. Just get out in the sunshine and take a walk. Don’t over-exercise because that becomes stress. When you’re sick, certainly, stay home. I use cannabinoids to calm the flames. I call that the dimmer switch on the immune system. I get a lot of things from quicksilverscientific.com. That’s Chris Shade’s company. [00:53:14] Ashley James: I’ve had him on the show. He’s got a glutathione as well—oral glutathione. [00:53:21] Dr. Judy Mikovits: That’s what I was going to say. He’s got a new product that he just gave A, D, K, and E because usually you can’t get vitamins A, D, K, and E except from fats, except from meats because you’ll be deficient in those if your food is contaminated. We eat healthy farm-grown. I mean all the way from eggs and meat we know our farmer. My friend, Dr. Zach Bush, said a few years ago on a Del Bigtree show, he said, “Forget your doctor, know your farmer.” Get good healthy eggs. It’s difficult in this world to be vegan because you need A, D, K, and E, but I do know that Chris Shade just came out with a new product that has those. He has a liposomal vitamin C. I’m not encouraging that we just supplement, supplement, supplement, just eat healthy food, but here in this day and age, we really do need to supplement glutathione. It’s from Quicksilver Scientific. They have something called ultra-binder. It’s charcoal, it’s a fulvic humic charcoal blend that I just shake. One little packet a day I think it cost, I don’t know. It can’t cost 50 cents. Maybe $1, who knows. I shake it up in the morning and I simply just take the ultra-binder in good clean water. We’ve got to have good clean filtered water. Fiji water, the brand name Fiji is great for removing aluminum. It’s a little bit of everything. That ultra-binder will even take out mercury and vaccine contaminants in things that we’ve been talking about and you can begin to detox. Just the most important thing is to keep away from inflammation. That by definition means I don’t care if the vaccine is the cleanest thing in the world, it’s intended to inflame. See, the way coronaviruses, let’s just say if that really had anything to do with COVID-19, which I don’t believe for a minute, the way coronaviruses cause damage is first they deplete your antioxidants. Antioxidant-rich foods like we’ve just mentioned—vitamin c. I have a cup of hot lemon water every day. Make sure your food is non-GMO and organic as possible because the soil becomes contaminated with glyphosate. I use ultra-binder. Just to eat as clean as you can so that ultra-binder will take out yesterday’s toxins. Even if you can’t eat clean—most processed foods and things you’re getting from the grocery store are loaded with glyphosate. The less processed food you can eat, the more fresh vegetables, fruits, blueberries, rich in antioxidants, the colors, the cyan, and the phytonutrients. This is the best we could do, but it’ll make you healthy. No such thing as social distancing. Please, hug people. Think of isolated babies. Think of the boy in the bubble, the those with primary immune deficiencies. Think of orphanages that we used to see visions of in Russia and things like that. They’re profoundly diseased and compromised because of a lack of touch. We’re human beings, and this is the worst thing about those face masks. No cloth face coverings. That just stops you from smiling, stops you from loving. Like you said, you get dirty looks. We’re made to smile. Anger is immunosuppressive. Fear is immunosuppressive. They’re not immune boosting. Those are horrible emotions. We’re generating this hate and it’s driving the compromising of our own immune system such that when they release the next thing on us, we will be susceptible. Hopefully, we won’t. I could say this from a lot of experience because it really doesn’t matter what they release. I’ve worked with everything. I’ve worked with Ebola. I’ve worked with the XMRVs. When your audience reads our two books, you’ll see from the first book Plague that the lab workers got infected. In 2011, we realized these cancer-causing viruses and neuro-immune disease-causing viruses, Lou Gehrig’s, Parkinson’s, chronic Lyme disease, and other things. These viruses and ME/CFS release devastating diseases were contagious that you could literally cough them on somebody, that you could get them from the air. I was the one in my laboratory, I made sure my students, the young people, didn’t get anywhere near the blood samples, didn’t do the work that generated aerosols that spread aerosols around. I did all the work and I got a boatload. I zero converted. I got a ton of XMRVs of these viruses in my body, in my blood. What measures do I take to keep myself well? I am not sick, I zero converted a decade ago, and I wouldn’t dare put on a mask. I hate to say it but I’m the people they want to kill. The people that they have liability for that they knowingly injected for decades with cancer-causing viruses, and I mean injected. If you think about it rationally, yeah, if I haven’t been on a plane, if I’ve been nowhere close to somebody in China, I didn’t go to a seafood market, I never went to one of the clusters of diseases—let’s just say New York City or Seattle where there were a few ground zero. I never went anywhere near any of those people. How exactly did I get exposed? When exactly? We didn’t do this with HIV. We did tell people don’t touch them, and that hurt them a great deal, injured their disease, and immune-compromised them. I didn’t obey that then either and I’m just fine, aren’t I? This is the point. We didn’t shut down the world. There are all the data that this coronavirus—yes, it caused a dangerous cost. Yes, there are compromised people who did die from exposure to it, but when you go watch those two shows I mentioned to you, The Highwire last week, in particular, they put the compromised in hospital wings who were clearly COVID negative in positive wings and then they stopped them from getting oxygen. You remember the cannula of oxygen you put in your nose when somebody needs oxygen or you put when you’re in an ambulance? What do they give you? They give you that little thing to breathe oxygen. They don’t intubate you. They don’t paralyze your breathing apparatus input. You can easily look at desaturation. All these things that oxygen desaturates. Just put the little thing on your finger and you can see how much oxygen you’re getting. You can see if you’re being compromised. Why aren’t we doing any of that? Why aren’t we taking care? Type I interferon 50-200 units. Type I interferon in a spray form, 50 to a couple hundred. Literally, a couple of hundred units a day sprayed in your nasal passages just like you would do a saline nasal spray will prevent anything that gets into your nasopharyngeal cavity from replicating any coronavirus. [01:01:52] Ashley James: Thank you so much for your time. I know you have to go. I am, of course, left with more questions. [01:01:59] Dr. Judy Mikovits: I’d be happy to talk to you again. You can tap Kent and talk to him a little bit to round out this one and then we’ll talk again, no problem. We can even take questions from your audience and go again. [01:02:09] Ashley James: That would be great. I’d love that. Yes, I definitely have more questions. I have them written down. And I know my listeners would have questions for you. I can’t wait to interview your co-author, Kent. It sounds wonderful. Thank you so much for taking the time today to educate us. We have to open our minds. I love the saying open your mind so much that your brain could fall out. Just open your mind and take in new information because that’s how we’re going to figure out how to best support our body’s ability to heal itself. The problem is when we listen to the mainstream there’s always an agenda. We have to protect ourselves from fear-mongering, but also stay safe. We want to stay safe, but we have to support our body’s ability to be healthy. You have so much great information. You have two books I highly recommend. The links to both your books, Plague and Plague of Corruption, will be in the show notes of today’s podcast at learntruehealth.com. Do you have anything you’d like to say to the listeners? Maybe homework to give them to wrap up today’s interview. [01:03:09] Dr. Judy Mikovits: Think about it really in a calm way and think about what I was saying as far as what do you do when you feel good? You go out to the ocean; you go out to the sand. You get tired, you get a little sunburned, you get a little exhausted, and you sleep really well. Those things that make you feel good. Just think, we never had to wear a mask in public. The silliness of you have to wear a mask when you enter here but as soon as you turn around and sit down, you don’t need one. That’s a control issue. That’s fear and anger. That’s intended to generate an emotional response. We don’t have to be emotional. We love each other. Nobody wants anybody to get sick. We want to spend our lives trying to heal people, that’s what we do. We just want to love each other. That’s how we stay well as a society and as families and individuals [01:04:10] Ashley James: Beautiful. Thank you so much. I can’t wait to have you back on the show. It’s been such a pleasure to have you here today. [01:04:16] Dr. Judy Mikovits: Thanks, Ashley. Get Connected With Dr. Judy Mikovits! Plague The Book Website Twitter Books by Dr. Judy Mikovits Plague Plague of Corruption
In today's quick hitter, I take less than 5 minutes to pass along an update from the CDC about prenvar in adults. RIP ol buddy, you served almost no one any good. NNT 26,000? Yikes. So you're telling me there's a chance!
In today's episode, we discuss getting rid of adult prevnar vaccination? What the evidence/experts say, and whether or not to expect a major guideline shift soon-ish? Pros and Cons, etc, etc, etc, Also, is recommending 10,000 steps daily to patients evidence based? (Spoiler: NOPE)
A look at this common and controversial topic. Hosts: Brian Gilberti, MD Audrey Bree Tse, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Acute_Otitis_Media.mp3 Download Leave a Comment Tags: Pediatrics Show Notes Background: The most common infection seen in pediatrics and the most common reason these kids receive antibiotics The release of the PCV (pneumococcal conjugate vaccine), or Prevnar vaccine, has made a big difference since its release in 2000 (Marom 2014) This, along with more stringent criteria for what we are calling AOM, has led to a significant decrease in the number of cases seen since then 29% reduction in AOM caused by all pneumococcal serotypes among children who received PCV7 before 24 months of age The peak incidence is between 6 and 18 months of age Risk factors: winter season, genetic predisposition, day care, low socioeconomic status, males, reduced duration of or no breast feeding, and exposure to tobacco smoke. The predominant organisms: Streptococcus pneumoniae, non-typable Haemophilus influenzae (NTHi), and Moraxella catarrhalis. Prevalence rates of infections due to Streptococcus pneumoniae are declining due to widespread use of the Prevnar vaccine while the proportion of Moraxella and NTHi infection increases with NTHi now the most common causative bacterium Strep pneumo is associated with more severe illness, like worse fevers, otalgia and also increased incidence of complications like mastoiditis. Diagnosis The diagnosis of acute otitis media is a clinical one without a gold standard in the ED (tympanocentesis) Ear pain (+LR 3.0-7.3), or in the preverbal child,
A look at this common and controversial topic. Hosts: Brian Gilberti, MD Audrey Bree Tse, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Acute_Otitis_Media.mp3 Download Leave a Comment Tags: Pediatrics Show Notes Background: The most common infection seen in pediatrics and the most common reason these kids receive antibiotics The release of the PCV (pneumococcal conjugate vaccine), or Prevnar vaccine, has made a big difference since its release in 2000 (Marom 2014) This, along with more stringent criteria for what we are calling AOM, has led to a significant decrease in the number of cases seen since then 29% reduction in AOM caused by all pneumococcal serotypes among children who received PCV7 before 24 months of age The peak incidence is between 6 and 18 months of age Risk factors: winter season, genetic predisposition, day care, low socioeconomic status, males, reduced duration of or no breast feeding, and exposure to tobacco smoke. The predominant organisms: Streptococcus pneumoniae, non-typable Haemophilus influenzae (NTHi), and Moraxella catarrhalis. Prevalence rates of infections due to Streptococcus pneumoniae are declining due to widespread use of the Prevnar vaccine while the proportion of Moraxella and NTHi infection increases with NTHi now the most common causative bacterium Strep pneumo is associated with more severe illness, like worse fevers, otalgia and also increased incidence of complications like mastoiditis. Diagnosis The diagnosis of acute otitis media is a clinical one without a gold standard in the ED (tympanocentesis) Ear pain (+LR 3.0-7.3), or in the preverbal child,
In the kickoff series of the Get Science Podcast, we’re focusing on scientific careers of people working in biopharma, and their different paths and opportunities taken as they hunt for potential cures to human disease.Vaccine research and development just like drug development is risky and challenging work in the pharmaceutical industry. But Kathrin Jansen, Senior Vice President and Head of Vaccine Research and Development at Pfizer, has risen to the upper echelons of the industry based on her flexibility, ability to trust her gut and her determination.Born in Communist East Germany, Jansen’s parents fled to the West where she grew up and eventually earned a PhD in biology at Philipps University in Marburg. She later came to the U.S. to do post-doctoral research at Cornell University. While she initially intended to work in small-molecule drug development, she pivoted to vaccines early on and since then has been involved in the development of three successfully licensed vaccines (Gardasil, Prevnar-13 and Trumenba).Learn more about Jansen’s career journey here.
What's the real truth on eggs? Good for you? Terrible for you? Let's see what the latest study says about eggs and your heart. Pneumonia is a leading cause of infectious death. There are new medicines in the works to treat it and 2 different vaccines available to prevent it. Do you need a pneumonia vaccine? Tanner does. Ready your hand squeezers! Apparently, stronger grip leads to longer life expectancy. We hope you join us as we dive deep into medicine so you don't have to. You stay safe (and informed) swimming in the shallows. We present the best studies and research in easy to understand and entertaining ways. We gladly accept show topics and ideas from our listeners: questions@healthfilesradio.com
Today, Gary and Tom delve into the insane price discrepancy between women's and men's haircuts, jowly automobile-dealer spokesmen, and bizarre names for pharmaceutical drugs. Plus viewer mail, a potential transgender-person social experiment, and a theremin!
Life of the School Podcast: The Podcast for Biology Teachers
Lindsey L’Ecuyer is a Biology teacher at Andover High School in Andover Massachusetts. For 9 years, Lindsey has taught Biotechnology, Forensics, Biology, Chemistry, and Anatomy & Physiology. Last spring, Lindsey was awarded a grant that from the Punchard Fund grant for advanced biotech equipment. Lindsey credits the broader Andover community for their continued support including grants from the Corbett Grant, Punchard Grant, AHS Parents Advisory Council, Andover Coalition for Education, and Andover Educational Improvement Association. Lindsey is very engaged at helping her students with real world science experiences that extend beyond the walls of her school building. These include taking her Forensics class to a behind-the-scenes-tour with Andover Police Detectives, initiating a BioBuilder Synthetic Biology Club, bringing the Biotechnology students to Pfizer for a site visit where the Prevnar pneumococcal vaccine is produced, and leading her students through the Wolbachia Project.. You can Follow Lindsey on twitter @ahsbiotech where she occasionally tweets about her work. Lindsey graduated from Stonehill College in 2006 where she received a degree in Biology, and she earned an M.Ed from Salem State University in 2011.
In this month's episode, we discuss the causes of diarrhea and the danger of dehydration. We give tips for how to know your child is ready for preschool or kindergarten, and discuss seasonal allergies. In our Health News segment, we discuss the PCV 13 (Prenar 13) vaccine, which replaces the PCV 7 vaccine. Finally, we give the answer to last month's medical trivia question -- What famous character in music history suffered from deafness and depression? Topic -- Time PCV 13 vaccine -- 1:48 Diarrhea and dehydration -- 5:36 Signs of Kindergarten Readiness -- 17:22 Seasonal Allergies -- 24:45 Medical Trivia -- 28:48 When you call our number (812-214-KIDS), you will be connected to our voicemail. Leave a question for the doctors and we may use your recorded message in an upcoming show! Listen Now: Kids Healthcast Episode 7 //