Podcasts about phytocannabinoid

A behavioural neuroscientist in Saskatoon is uncovering marijuana's effects on fetal brain development.  After recently winning a five-year CIHR grant of $960,076 in the spring of 2024, Dr. John Howland's lab at the University of Saskatchewan is expanding its work examining prenatal exposure to cannabis smoke. Howland's teams will assess the way cannabis exposure alters higher brain functions like memory and learning in both rats and mice. Compared to cannabis injections in the past, the professor of Anatomy, Physiology and Pharmacology at the College of Medicine said exposing rodents to high-potency smoke for up to 15 minutes at a time provides a more realistic picture of marijuana's effects on fetal brain development.  Over their lives, Howland will measure changes in cortical limbic circuitruity, for both rodent mothers and their offspring.  “The cortex is definitely involved, but we also look at other areas like the hippocampus and the amygdala,” said Howland. “There's pretty good evidence that they are at least subtly affected after gestational exposure to cannabis.” Now, it's a matter of quantifying which circuits cannabis affects in the rodent brain — under circumstances as close to real-life human exposure as Howland's laboratory can create.  "It's not simple," said Howland. He notes a wide variety of phenotypes of THC and CBD strains are now available at retailers, each with its own characteristics and potential interactions with neurons.  “These receptors are involved in many discrete events during brain development,” he said. "We're hoping to be more controlled and more specific."  Howland's team is also searching for ways to stem damage from high-potency strains, while exploring therapies like exercise to counteract cannabis exposure and help future generations grow healthier brains.   He said cannabis may be legal -- but that does not make it safe. "It turns out a lot of things that are legal like alcohol and tobacco aren't that safe during pregnancy either," said Howland. "I think more knowledge has to be helpful as women make these decisions for themselves.”

On the latest episode of The Cannabis Conversation, we're joined by Dr. Callie Seaman, Research Director and Formulation Chemist at AquaLabs - nutrient solution provider to the hobby and medical horticultural market, and UK licensed medical cannabis cultivation research facility. We investigate some of the biggest cannabis myths, including why cannabis should not be seen as a cure, why THC should not be demonised, and why we need to be more realistic about what cannabis can achieve. 

This week, we're joined by Valentino Parravicini, Chief Scientific Officer at Oxford Cannabinoid Technologies - British pharmaceutical company developing a portfolio of next-generation prescription cannabinoid medicines.In this episode, we explore the potential use of cannabis-based medicines as a replacement for prescription opioids, their safety profile, and their use cases as analgesics. 

In this episode, we're joined by Andrew Sears, Business Development Associate at Seedrs - Europe's biggest crowdfunding platform.We explore how equity crowdfunding fits into the wider cannabis investment landscape in the UK, and what Seedrs is doing to help UK cannabis startups grow.

This week we're excited to welcome Mags Houston and Dr. Anne Katrin Schlag from Drug Science - independent science led drugs charity based in London.Together, we explore how ProjectTwenty21 is progressing, some of the initial findings from the participating patient set, alongside digging into the true value of real-world data as a form of medical evidence opposed to randomised controlled trials.The Cannabis Conversation is sponsored by Lumino  - a boutique HR and Recruitment Agency specialising in building high performance teams for the European Cannabis Industry. They work in three main verticals: Commercial, Medical and Plant Facing.Get in touch at www.luminorecruit.com/

In our latest episode, we're joined by Paul Steckler, Managing Director for Canopy Growth International. We discuss the challenges of fitting cannabis production into a traditional pharmaceutical medical framework, along with some of the biggest UK-centric, economic and market challenges associated with operating within this space.

This week's episode comes to you from Odense in Denmark, where we're joined by Connor Jensen Murphy and Justin Ihnken from Danish full service cannabis testing and analysis lab, QNTM Labs.We examine the importance of continuity, standardisation, and frameworks with the context of cannabis laboratory testing, and how QNTM Labs are helping to bring pharmaceutical testing standards to the European medical cannabis industry.About QNTM LabsQNTM Labs is an advanced analytical laboratory providing research, development, and regulatory compliance services for pharmaceutical companies.Founded in 2020 and headquartered in Odense, Denmark, QNTM is dedicated to developing innovative analytical methods while maintaining the highest quality levels to forge new industry standards.As global sentiment is increasingly focused on quality data, QNTM Labs is determined to improve transparency and access to robust scientific analysis, working hand-in-hand with global cultivators, API manufacturers, and pharmaceutical industry stakeholders through analytical testing, contract research and clinical trials support.About Justin IhnkenJustin Ihnken is the Chief Executive Officer and Co-founder of QNTM Labs, a state-of-the-art GMP-certified laboratory dedicated to supporting plant-based pharmaceuticals. Outside of QNTM Labs, Justin also currently sits on the Board of Directors for the American Club of Copenhagen.Prior to founding QNTM Labs, Justin worked in Copenhagen for Danish global shipping conglomerate, A.P. Møller-Mærsk, where he was responsible for interest rate portfolio management and derivative trading, as a part of the company's global treasury team. Before moving to Denmark in 2018, Justin built his professional career in institutional banking in New York City, within fixed income trading and interest rates.  Justin completed his education at Seton Hall University's Stillman School of Business where he studied Mathematical Finance. About Connor Jensen MurphyConnor Jensen Murphy co-founded QNTM Labs in March 2020 and is currently the company's Chief Operating Officer.  Connor has spent his career advising middle-market and founder-owned companies in corporate restructuring and M&A transactions.Prior to starting QNTM, Connor was a VP on EY's Investment Banking team in Copenhagen focused on M&A transactions. Before moving to Copenhagen, he was based in San Francisco, California and also worked with EY's Investment Banking group. Connor holds a B.A. from Colgate University where he studied Environmental Economics.ResourcesFollow QNTM Labs on LinkedIn: https://www.linkedin.com/company/qntmlabs/QNTM Labs Website: https://qntmlabs.com/Connect with Connor on LinkedIn: https://www.linkedin.com/in/connor-jensen-murphyConnect with Justin on LinkedIn: https://www.linkedin.com/in/justin-ihnken

On this week's episode, we're joined by Professor Mike Barnes, Neurologist, Director of Maple Tree Consultancy, and Chairman of The Medical Cannabis Clinicians SocietyWe explore the future of Medical Cannabis in the UK by investigating current prescribing practices, stakeholder challenges, and how the government can help develop the industry.→ View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e135About Professor Mike BarnesProfessor Mike Barnes is a neurologist and cannabis physician. He has worked in cannabis for 20 years, initially with GW Pharma on the first cannabis medicine - Sativex. He oversaw the first UK cannabis prescription for the child Alfie Dingley in 2018 and, after the law change in November 2018, then launched the Medical Cannabis Clinicians Society in November 2018 which now has over 250 clinical members. In 2021 he launched the Cannabis Industry Council with over 100 members across the sector. He runs a medical cannabis consultancy with Hannah Deacon who is the UK's best-known campaigner and mother of Alfie Dingley. He is the Clinical Director of the T21 project.Quotables‘[Cannabis'] medical history is actually more prominent and more robust… than its recreational history' 09:36‘It's down to education. And I think it's Tony Blair that said, education, education, education. And that's the same with cannabis. It's absolutely essential to educate the doctors first, educate politicians after say second, but it's mainly the conservatism of medical professionals holding it back now' 27:45ResourcesThe Medical Cannabis Clinicians Society Website: https://www.ukmccs.org/Professor Barnes' LinkedIn: https://www.linkedin.com/in/michael-barnes-6048b223/Maple Tree Consultants LinkedIn: https://www.linkedin.com/in/michael-barnes-6048b223/#Cannabis Industry Council Website: https://cannabisindustrycouncil.org/Professor Mike Barnes' Website: https://www.profmichaelbarnes.co.uk/

This week we have pro triathlete Jeanni Metzler who has been all over the podiums at IRONMAN 70.3 races all year.  Jeanni joining us to talk about her 2nd place at St George beating out friend and competitor Taylor Knibb.  The 29 year old pro lives in Boulder with her husband Taylor "BigMetz" and dog Milli. Show Sponsor: VENGA CBD   We're huge fans of Venga CBD. It really helps us recover more quickly from our workouts, have less soreness, sleep better and reduce inflammation.   Highlights: Nano-emulsified CBD making it water-soluble for high bioavailability. Phytocannabinoid rich CBD containing over 110 cannabinoids, 10 times that of typical industrial hemp. No THC. This is NOT an isolate - our CBD is whole hemp plant CBD. Curcumin added as an additional herbal extract to target inflammation.    Just go to https://vengaendurance.com/303podcast to order yours today. First-time order is 30% off with code (303PODCAST).  We've also added 50% off your first month's subscription with code (303SUBSCRIPTION).   In Today's Show Feature interview with Jeanni Metzler (2nd at St George) Endurance News 2021 IRONMAN Chattanooga Results Study Women's Hearts Respond -Differently to Marathon Training Than Mens What's new in the 303 Still a couple of triathlons in October and Cold weather riding tips Video of the Week Ironman Chattanooga Highlights   Interview Sponsor: UCAN Take your performance to the next level with UCAN Energy and Bars made with SuperStarch®  UCAN uses SuperStarch instead of simple sugars to fuel serious athletes.  UCAN keeps blood sugar steady compared to the energy spikes and crashes of sugar-based products.  Steady energy equals sustained performance!   You put in the training, so don't let nutrition limit your performance.  Use UCAN in your training and racing to fuel the healthy way, finish stronger and recover more quickly!  Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co   Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co,    Interview with Jeanni Metzler (aka Metzler) Jeanni Metzler (formerly Seymour) is a multiple 70.3 winner who also moved up to the full distance in 2019 with a podium finish at IRONMAN Texas.   Born and raised in South Africa, she now lives and trains alongside her husband and fellow pro Justin Metzler in Boulder, and she has claimed emotional victories in both locations.   Tracing her journey to Colorado, she says: "My cousin got me into road cycling when I was about 17 and then introduced me to a local triathlon group in Johannesburg, the rest was history!"   She won her age group at her first 70.3 race in Buffalo City, East London in 2011. Taking up the chance to be a professional in 2012 as she turned 20, she had to make a drastic decision to give herself the best chance of success.   Jeanni explains: "I left South Africa with pretty much nothing - but, with the support of my family, I was able to make a life for myself as a professional athlete in the United States."   The first couple of years were tough, but her breakthrough moment came late in 2015 when she won IRONMAN 70.3 Austin thanks to a storming run. This was to become a common theme.   Jeanni came back a year later to defend her title and then won the inaugural 70.3 Xiamen race that November.   She was on her way now, and the wins started to stack up. In 2017 there were four 70.3 titles at Liuzhou, Monterrey, Boulder and Los Cabos, as well as a first top-10 in the 70.3 World Championship in Chattanooga. Just for good measure, she grabbed a Challenge Iceland title too.   But it was the triumph in her adopted home of Boulder which struck a chord and showed how far she'd come. She had previously been sixth in 2015 and runner-up in 2016.   There were also two significant returns to her country of birth in 2018, first to win 70.3 South Africa (at the scene of that 2011 age-group success) and then to place seventh in the 70.3 World Championship at Port Elizabeth.   Our News is sponsored by Buddy Insurance. It's big time training and racing season.  Buddy Insurance is the kind of peace of mind so you can enjoy your training and racing to their fullest.  Buddy's mission is simple, to help people fearlessly enjoy an active and outdoor lifestyle.  You can now get on-demand accident insurance to make sure you get cash for bills fast and fill any gaps between your current coverage.  Go to buddyinsurance.com and create an account.  There's no commitment or charge to create one.  Once you have an account created, it's a snap to open your phone and in a couple clicks have coverage for the day.  Check it out!   Endurance News:   Results (ironman.com)   Ironman Chattanooga for Sept 25, 2022 on Oct 4th 12p.   Study Women's Hearts Respond -Differently to Marathon Training Than Mens BRITTANY HAMBLETON SEPTEMBER 29, 2021 Over the last several decades, female athletes have often been left out of sports science research, and the majority of studies have focused primarily on young, healthy males as subjects. It has only been in recent years that researchers have begun to include women in their studies, and, perhaps not surprisingly, some differences are beginning to emerge. A recent study looking at the differences between male and female marathoners found that women's hearts actually respond differently than men's after training for a marathon.   The study The paper, entitled “Sex differences in cardiovascular adaptations in recreational marathon runners,” aimed to examine various changes in heart function in male and female marathoners and recreational athletes. The researchers included 52 marathoners (28 females and 24 males) who had completed five to seven marathons over three years and 49 recreationally active adults (25 females and 24 males) as controls.   The researchers studied the hearts of each participant, focusing on three main measurements:   Left ventricle function: the left ventricle pumps oxygen-rich blood to the rest of the body. Aortic stiffness: occurs when the elastic fibers within the arterial wall (elastin) begin to fray due to mechanical stress. Ventricular-vascular coupling: the ratio of arterial to left ventricle elastance, a key determinant of cardiac performance. The results After studying the hearts of all the participants, the researchers found that women who have completed multiple marathons do not have reduced left ventricle function or aortic stiffness compared to male marathoners or female recreationally active athletes (both of which are good things). Interestingly, they appear to have better ventricular-vascular coupling compared to the other test groups, which means their hearts are more mechanically efficient after undergoing a marathon training cycle. In other words, women's hearts may respond better to marathon training than men's.   The reason for this is unclear, but the researchers believe it could have something to do with the estrogen levels in female athletes. Studies show that estrogen positively modulates cardiac hypertrophy (the heart's tendency to get bigger with training), lowers blood pressure and decreases arterial stiffness, all of which make for a healthier, stronger heart.   The researchers conclude the studying by acknowledging that future studies are needed to better understand the influence of sex hormones (in particular, estrogen) on cardiovascular adaptations in marathon runners. This will create a greater understanding of how women adapt to marathon training and may lead to better training protocols for female distance runners in the future.   Brownlees Step Aside, Alex Yee is The New Heir to The British Tri Throne – Triathlete   What's New in the 303:   Still a Couple of Triathlons in Colorado in October The Last Call Triathlon at Boyd Lake near Loveland was the last triathlon along the front range but there are still a couple of opportunities to race in Montrose and Alamosa. The Black Canyon Triathlon (Montrose) October 2nd and the Splashland Triathlon (Alamosa) October 19th are still on the calendar. These are pool based triathlons and in Alamosa the pool is a hot springs–and the swim is last.   With fall colors peaking in the high country, a trip to either venue will be full of color and adventure. We caught up with Montrose resident Julie Burdick who participates in all of the Southwestern Triathlon Series triathlons to learn more. As a busy mom of twins and recovering from Covid, she is looking forward to this week's triathlon more than ever.   Ready for Some Cold Weather Riding? Some “Pro Tips” on Embrocation Products Posted on September 29, 2021 By Val Sanford   With cooler weather heading our way (finally) and cyclocross season upon us, now might be the time to try embrocation to help warm those muscles up. Here are some “pro tips” from a top maker–Bluerub.     PERFORM BETTER IN COLD WEATHER   If you cycle in cold weather, use an embrocation product like bluerub's MUSCLE to increase your comfort while riding. You'll add warmth and increased circulation to your legs, so you can ride farther and go longer.    HOW EMBROCATION WORKS   Embrocation products blend warming ingredients like capsicum, mint essential oils, clove oil, black pepper essential oil, camphor, and menthol to signal the body to “warm-up” the area where it was applied. When used before cold-weather exercise, it acts as a signal to tell the body to increase circulation to the legs. You'll feel the cold less, and your legs will thank you.   7 PRO-TIPS FOR USING EMBROCATION   EMBRO AFTER YOU KIT UP You've got the idea now that embrocation is all about warming! So you'll want to put on your kit first. That will keep all those warming oils away from the parts of your body you definitely don't want to ‘warm-up.” Think capsicum blended into your chamois. Yikes!   APPLY ABOUT 30 MINUTES BEFORE YOU RIDE Typically, you'll feel the effects of embrocation about 30 minutes after you apply it. But everyone's body is different, so you'll want to do some experimentation before a big race. This means you'll need to be thinking about your pre-race/pre-ride routine and make sure you've given yourself plenty of time.   Remember, though, that embrocation products won't replace your warm-up. You'll still need to stretch, warm-up, and do your pre-ride physical routine.   Pro-tip: Apply CHAMOIS first, for the obvious reasons.   REALLY WORK IT IN I've heard some say they channel their inner massage therapist to really work the embrocation into the muscles and to thoroughly cover the skin. Roll down your socks, roll up the legs of your bibs, and really spend a few minutes working it in. While legs are the most common spot, you can apply to your lower back, shoulders, neck, and ankles.   When you use something that is also a recovery product, like MUSCLE, you'll get a double benefit from the massage in helping relieve any leftover pre-ride stiffness or soreness in your muscles. You can even reapply after your shower to give sore spots some relief.   Pro-tip: not all embrocation products are non-staining. So do a spot test before going all-in on your favorite kit.   AVOID YOUR EYES, MOUTH, AND OTHER SENSITIVE PARTS You know how much you hate it when you've been cutting peppers and then touch your eye or your lip? Well, that's what it'll feel like if you touch your eyes after applying embro. Wash your hands with warm soap and water, or use a wipe (although this may not get all of it off your hands). You can also use single-use gloves to apply and then toss. It's not an eco-friendly solution, but it can save you on a race when you don't have access to warm, soapy water.   Pro-tip: Fill your bottles, pack your phone, snacks, and other essentials before applying embrocation, just to be on the safe side.   KEEP YOUR LEGS WARM Embrocation creams don't actually add any extreme cold-weather protection to your legs. So if you're riding in chilly weather – especially if there's a breeze — you'll need to protect your legs from the elements. Try using knee warmers or even thermal tights (with our without embrocation). Be mindful of how cold it is and be aware of how it's affecting you.   Pro-tip: Use an embrocation even when the weather isn't cold. It is a great transition solution between cool weather when tights are too much, yet you want a little extra warmth before getting out for a ride.   SHAVE YOUR LEGS Embrocation products come in a variety of forms: oils, balms, salves, creams. bluerub's MUSCLE's is a lightweight cream that goes on smoothly. If your legs are hairy, it can get caught in the hair and not be thoroughly or evenly applied. The embrocation will wash off more fully and easily on smooth skin. Plus, you know you look great with shaved legs! (Try SHAVE for smooth, soft skin.)   Pro-tip: Don't apply on just-shaved legs. Give your pores a little breathing room before using warming oils like those in an embrocation product.   WASH BEFORE YOU SHOWER I love settling into a hot, steamy bath after being outside in the cold, wet weather. But hot water can reactivate the essential oils and give you the surprise of your life! Okay, not the surprise of your life, but you could definitely feel like jumping out of the water!   Use warm, soapy water to remove the embrocation before getting into a hot shower or bath. No-rise wipes can help but may not get all the oils off, so test it to be sure.   Pro-tip: Don't use the same washcloth to wash your face. Some people like using a loofah to help remove the embrocation. Just like your washcloth, keep it 'embrocation only' to avoid any accidental application to your face or nether parts.   So those are our pro-tips for using embrocation cream during cold weather rides.    Video Of The Week: Ironman Chattanooga 2021 Highlights   Closing: Thanks again for listening in this week.  Please be sure to follow us @303endurance and of course go to iTunes and give us a rating and a comment.  We'd really appreciate it! Stay tuned, train informed, and enjoy the endurance journey!

This week we have pro triathlete Jeanni Metzler who has been all over the podiums at IRONMAN 70.3 races all year.  Jeanni joining us to talk about her 2nd place at St George beating out friend and competitor Taylor Knibb.  The 29 year old pro lives in Boulder with her husband Taylor "BigMetz" and dog Milli. Show Sponsor: VENGA CBD   We're huge fans of Venga CBD. It really helps us recover more quickly from our workouts, have less soreness, sleep better and reduce inflammation.   Highlights: Nano-emulsified CBD making it water-soluble for high bioavailability. Phytocannabinoid rich CBD containing over 110 cannabinoids, 10 times that of typical industrial hemp. No THC. This is NOT an isolate - our CBD is whole hemp plant CBD. Curcumin added as an additional herbal extract to target inflammation.    Just go to https://vengaendurance.com/303podcast to order yours today. First-time order is 30% off with code (303PODCAST).  We've also added 50% off your first month's subscription with code (303SUBSCRIPTION).   In Today's Show Feature interview with Jeanni Metzler (2nd at St George) Endurance News 2021 IRONMAN Chattanooga Results Study Women's Hearts Respond -Differently to Marathon Training Than Mens What's new in the 303 Still a couple of triathlons in October and Cold weather riding tips Video of the Week Ironman Chattanooga Highlights   Interview Sponsor: UCAN Take your performance to the next level with UCAN Energy and Bars made with SuperStarch®  UCAN uses SuperStarch instead of simple sugars to fuel serious athletes.  UCAN keeps blood sugar steady compared to the energy spikes and crashes of sugar-based products.  Steady energy equals sustained performance!   You put in the training, so don't let nutrition limit your performance.  Use UCAN in your training and racing to fuel the healthy way, finish stronger and recover more quickly!  Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co   Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co,    Interview with Jeanni Metzler (aka Metzler) Jeanni Metzler (formerly Seymour) is a multiple 70.3 winner who also moved up to the full distance in 2019 with a podium finish at IRONMAN Texas.   Born and raised in South Africa, she now lives and trains alongside her husband and fellow pro Justin Metzler in Boulder, and she has claimed emotional victories in both locations.   Tracing her journey to Colorado, she says: "My cousin got me into road cycling when I was about 17 and then introduced me to a local triathlon group in Johannesburg, the rest was history!"   She won her age group at her first 70.3 race in Buffalo City, East London in 2011. Taking up the chance to be a professional in 2012 as she turned 20, she had to make a drastic decision to give herself the best chance of success.   Jeanni explains: "I left South Africa with pretty much nothing - but, with the support of my family, I was able to make a life for myself as a professional athlete in the United States."   The first couple of years were tough, but her breakthrough moment came late in 2015 when she won IRONMAN 70.3 Austin thanks to a storming run. This was to become a common theme.   Jeanni came back a year later to defend her title and then won the inaugural 70.3 Xiamen race that November.   She was on her way now, and the wins started to stack up. In 2017 there were four 70.3 titles at Liuzhou, Monterrey, Boulder and Los Cabos, as well as a first top-10 in the 70.3 World Championship in Chattanooga. Just for good measure, she grabbed a Challenge Iceland title too.   But it was the triumph in her adopted home of Boulder which struck a chord and showed how far she'd come. She had previously been sixth in 2015 and runner-up in 2016.   There were also two significant returns to her country of birth in 2018, first to win 70.3 South Africa (at the scene of that 2011 age-group success) and then to place seventh in the 70.3 World Championship at Port Elizabeth.     Our News is sponsored by Buddy Insurance. It's big time training and racing season.  Buddy Insurance is the kind of peace of mind so you can enjoy your training and racing to their fullest.  Buddy's mission is simple, to help people fearlessly enjoy an active and outdoor lifestyle.  You can now get on-demand accident insurance to make sure you get cash for bills fast and fill any gaps between your current coverage.  Go to buddyinsurance.com and create an account.  There's no commitment or charge to create one.  Once you have an account created, it's a snap to open your phone and in a couple clicks have coverage for the day.  Check it out!   Endurance News:   Results (ironman.com)         Ironman Chattanooga for Sept 25, 2022 on Oct 4th 12p.   Study Women's Hearts Respond -Differently to Marathon Training Than Mens BRITTANY HAMBLETON SEPTEMBER 29, 2021 Over the last several decades, female athletes have often been left out of sports science research, and the majority of studies have focused primarily on young, healthy males as subjects. It has only been in recent years that researchers have begun to include women in their studies, and, perhaps not surprisingly, some differences are beginning to emerge. A recent study looking at the differences between male and female marathoners found that women's hearts actually respond differently than men's after training for a marathon.   The study The paper, entitled “Sex differences in cardiovascular adaptations in recreational marathon runners,” aimed to examine various changes in heart function in male and female marathoners and recreational athletes. The researchers included 52 marathoners (28 females and 24 males) who had completed five to seven marathons over three years and 49 recreationally active adults (25 females and 24 males) as controls.   The researchers studied the hearts of each participant, focusing on three main measurements:   Left ventricle function: the left ventricle pumps oxygen-rich blood to the rest of the body. Aortic stiffness: occurs when the elastic fibers within the arterial wall (elastin) begin to fray due to mechanical stress. Ventricular-vascular coupling: the ratio of arterial to left ventricle elastance, a key determinant of cardiac performance. The results After studying the hearts of all the participants, the researchers found that women who have completed multiple marathons do not have reduced left ventricle function or aortic stiffness compared to male marathoners or female recreationally active athletes (both of which are good things). Interestingly, they appear to have better ventricular-vascular coupling compared to the other test groups, which means their hearts are more mechanically efficient after undergoing a marathon training cycle. In other words, women's hearts may respond better to marathon training than men's.   The reason for this is unclear, but the researchers believe it could have something to do with the estrogen levels in female athletes. Studies show that estrogen positively modulates cardiac hypertrophy (the heart's tendency to get bigger with training), lowers blood pressure and decreases arterial stiffness, all of which make for a healthier, stronger heart.   The researchers conclude the studying by acknowledging that future studies are needed to better understand the influence of sex hormones (in particular, estrogen) on cardiovascular adaptations in marathon runners. This will create a greater understanding of how women adapt to marathon training and may lead to better training protocols for female distance runners in the future.   Brownlees Step Aside, Alex Yee is The New Heir to The British Tri Throne – Triathlete   What's New in the 303:   Still a Couple of Triathlons in Colorado in October The Last Call Triathlon at Boyd Lake near Loveland was the last triathlon along the front range but there are still a couple of opportunities to race in Montrose and Alamosa. The Black Canyon Triathlon (Montrose) October 2nd and the Splashland Triathlon (Alamosa) October 19th are still on the calendar. These are pool based triathlons and in Alamosa the pool is a hot springs–and the swim is last.   With fall colors peaking in the high country, a trip to either venue will be full of color and adventure. We caught up with Montrose resident Julie Burdick who participates in all of the Southwestern Triathlon Series triathlons to learn more. As a busy mom of twins and recovering from Covid, she is looking forward to this week's triathlon more than ever.   Ready for Some Cold Weather Riding? Some “Pro Tips” on Embrocation Products Posted on September 29, 2021 By Val Sanford   With cooler weather heading our way (finally) and cyclocross season upon us, now might be the time to try embrocation to help warm those muscles up. Here are some “pro tips” from a top maker–Bluerub.   PERFORM BETTER IN COLD WEATHER   If you cycle in cold weather, use an embrocation product like bluerub's MUSCLE to increase your comfort while riding. You'll add warmth and increased circulation to your legs, so you can ride farther and go longer.    HOW EMBROCATION WORKS   Embrocation products blend warming ingredients like capsicum, mint essential oils, clove oil, black pepper essential oil, camphor, and menthol to signal the body to “warm-up” the area where it was applied. When used before cold-weather exercise, it acts as a signal to tell the body to increase circulation to the legs. You'll feel the cold less, and your legs will thank you.   7 PRO-TIPS FOR USING EMBROCATION   EMBRO AFTER YOU KIT UP You've got the idea now that embrocation is all about warming! So you'll want to put on your kit first. That will keep all those warming oils away from the parts of your body you definitely don't want to ‘warm-up.” Think capsicum blended into your chamois. Yikes!   APPLY ABOUT 30 MINUTES BEFORE YOU RIDE Typically, you'll feel the effects of embrocation about 30 minutes after you apply it. But everyone's body is different, so you'll want to do some experimentation before a big race. This means you'll need to be thinking about your pre-race/pre-ride routine and make sure you've given yourself plenty of time.   Remember, though, that embrocation products won't replace your warm-up. You'll still need to stretch, warm-up, and do your pre-ride physical routine.   Pro-tip: Apply CHAMOIS first, for the obvious reasons.   REALLY WORK IT IN I've heard some say they channel their inner massage therapist to really work the embrocation into the muscles and to thoroughly cover the skin. Roll down your socks, roll up the legs of your bibs, and really spend a few minutes working it in. While legs are the most common spot, you can apply to your lower back, shoulders, neck, and ankles.   When you use something that is also a recovery product, like MUSCLE, you'll get a double benefit from the massage in helping relieve any leftover pre-ride stiffness or soreness in your muscles. You can even reapply after your shower to give sore spots some relief.   Pro-tip: not all embrocation products are non-staining. So do a spot test before going all-in on your favorite kit.   AVOID YOUR EYES, MOUTH, AND OTHER SENSITIVE PARTS You know how much you hate it when you've been cutting peppers and then touch your eye or your lip? Well, that's what it'll feel like if you touch your eyes after applying embro. Wash your hands with warm soap and water, or use a wipe (although this may not get all of it off your hands). You can also use single-use gloves to apply and then toss. It's not an eco-friendly solution, but it can save you on a race when you don't have access to warm, soapy water.   Pro-tip: Fill your bottles, pack your phone, snacks, and other essentials before applying embrocation, just to be on the safe side.   KEEP YOUR LEGS WARM Embrocation creams don't actually add any extreme cold-weather protection to your legs. So if you're riding in chilly weather – especially if there's a breeze — you'll need to protect your legs from the elements. Try using knee warmers or even thermal tights (with our without embrocation). Be mindful of how cold it is and be aware of how it's affecting you.   Pro-tip: Use an embrocation even when the weather isn't cold. It is a great transition solution between cool weather when tights are too much, yet you want a little extra warmth before getting out for a ride.   SHAVE YOUR LEGS Embrocation products come in a variety of forms: oils, balms, salves, creams. bluerub's MUSCLE's is a lightweight cream that goes on smoothly. If your legs are hairy, it can get caught in the hair and not be thoroughly or evenly applied. The embrocation will wash off more fully and easily on smooth skin. Plus, you know you look great with shaved legs! (Try SHAVE for smooth, soft skin.)   Pro-tip: Don't apply on just-shaved legs. Give your pores a little breathing room before using warming oils like those in an embrocation product.   WASH BEFORE YOU SHOWER I love settling into a hot, steamy bath after being outside in the cold, wet weather. But hot water can reactivate the essential oils and give you the surprise of your life! Okay, not the surprise of your life, but you could definitely feel like jumping out of the water!   Use warm, soapy water to remove the embrocation before getting into a hot shower or bath. No-rise wipes can help but may not get all the oils off, so test it to be sure.   Pro-tip: Don't use the same washcloth to wash your face. Some people like using a loofah to help remove the embrocation. Just like your washcloth, keep it 'embrocation only' to avoid any accidental application to your face or nether parts.   So those are our pro-tips for using embrocation cream during cold weather rides.    Video Of The Week: Ironman Chattanooga 2021 Highlights   Closing: Thanks again for listening in this week.  Please be sure to follow us @303endurance and of course go to iTunes and give us a rating and a comment.  We'd really appreciate it! Stay tuned, train informed, and enjoy the endurance journey!

This week, we welcome back  Dominic Day & George Kruis to the show, international Rugby players, and Co-Founders of wellness brand for athletes - fourfive CBD.We examine the changing attitudes towards cannabis in professional sport, how CBD can be used to aid recovery from sports injuries, and how regulators view the substance.→ View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e132About George KruisGeorge Kruis is a professional rugby player with 12 years of experience playing International and club level rugby. His love for the sport and his exceptional skills have led him to not only gain three European titles and four Premiership trophies for English Premiership club Saracens; but also achieve over 45 caps for England during 2 World Cups and a British and Irish Lions tour.About Dominic DayDom Day was a professional rugby player for 14 years. He played in the 2015 Rugby World Cup for Wales, and has over 250 top flight games to his name. His long rugby career has taken him around the globe to places including Australia and Japan, finishing his career as a proud member of the English Premiership club Saracens where he fell in love with George & CBD.Quotables‘Nutrition is a hard market to break into… you have to be a cut above the rest' 09:50‘There is a necessity to look beyond painkillers and opioids' 17:50ResourcesVisit fourfive CBD's Website: https://fourfive.com/Join Dominic on Linkedin: https://www.linkedin.com/in/dominic-day-7a8a7770/Join George on Linkedin: https://www.linkedin.com/in/george-kruis-400032b9/Follow fourfive CBD on Instagram: https://www.instagram.com/fourfiveuk/?hl=en 

This week, we're joined by Sébastien Béguerie, entrepreneur and founder of Kanavape, Alpha-Cat and Golden Buds. Together we examine the methodologies and tests involved in the quality control of cannabis, their challenges, and the barriers to achieving consistent quality. Sébastien also shares his reflections on the Kanavape case - a significant milestone for the European CBD industry.→ View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e125About Sébastien BéguerieSebastien is one of Europe's leading experts in medical cannabis and CBD with more than 10 years of experience in cannabis production, regulation, education, and advocacy. Sébastien Béguerie holds an MSc in Plant Sciences, from Wageningen University Research in The Netherlands where he was kindly sponsored by Bedrocan. In 2009, he co-founded the first national medical Cannabis French patient association -  "l' Union Francophone pour les Cannabinoids en Médecine” (UFCM). Together with the association, Sébastien organises the international medical Cannabis conference in Strasbourg. In 2011 Sébastien founded his Alpha-cat in Europe, who manufacture cannabinoid testing kits and CBD products. In 2015, Sébastien created and launched the famous Kanavape brand in Europe which was the first CBD -cigarette to be sold in the region. In 2020 Sebastien started Golden Buds a new CBD brand mixing Californian CBD product innovation, with French luxury.ResourcesFollow Sébastien on LinkedIn: https://www.linkedin.com/in/sebastienbeguerie/?originalSubdomain=frFollow Sébastien on Instagram: https://www.instagram.com/alphacat_420/?hl=enGolden Buds Website: https://www.goldenbuds.eu/Alpha-Cat Website: https://www.alpha-cat.org/  

This week we're joined by Rhys Cohen, Australian Cannabis Consultant, and Editor at Large of Cannabiz Australia.In this episode, Rhys gives us a high level overview of cannabis down-under, including its changing public perceptions, patient access to medical products, and progress towards decriminalisation. → View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e110About RhysRhys has delivered consulting projects to most of Australia's leading cannabis companies and has worked extensively with the Lambert Initiative for Cannabinoid Therapeutics at the University of Sydney. He has presented at numerous industry events including ACannabis (2021); Prohibition Partners Live (2020); and New Frontier Global Cannabis Town Hall (2020). His industry analysis has been cited by Deloitte Access Economics; the Victorian Department of Economic Development, Jobs, Transport and Resources; the Commonwealth Office of Drug Control; the Commonwealth Senate Standing Committee on Community Affairs; and the International Journal of Drug Policy. Rhys has also appeared in ABC News; The Australian Financial Review, The Age; The Sydney Morning Herald; and MJBiz Daily. He is the editor-at-large for Australia's leading industry news platform Cannabiz. And he sits on the Advisory Board of market intelligence and research company FreshLeaf Analytics.Quotables‘[In Australia] the existence of the medical properties of cannabis are not disputed by anyone' 06:31Once it becomes easy and cheap enough here is no reason why other people who aren't medicinal cannabis patients could start accepting cannabis on prescription. That combined with the public change in attitudes towards cannabis legalisation more generally… I think we're approaching a point in which we're going to start having the initial conversation about cannabis law reform' 32:00ResourcesJoin Rhys on LinkedIn: https://www.linkedin.com/in/rhyscohen/Rhys's Website: https://www.rhyscohen.com/Join Rhys onTwitter: https://twitter.com/rhyscohenCannabis Australia: https://www.cannabiz.com.au/

How do synthetic cannabinoids compare to naturally occurring ones??This week we're joined by pharmacologist Dr Saoirse O'Sullivan and pharmacist Dr Andy Yates, experienced cannabis scientists and advisors to Artelo Biosciences.In this episode we take an in-depth look into cannabinoids, exploring the three classes - endocannabinoids, phytocannabinoids and synthetic cannabinoids in detail, alongside the uses, benefits and limitations of each type.→ View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e106About Dr Saoirse O'Sullivan, Ph.DProfessor Saoirse Elizabeth O'Sullivan received her doctorate from Trinity College Dublin in 2001 and moved to the University of Nottingham in 2002 as a Research fellow where she began researching cannabinoid pharmacology through basic and clinical research.  She was made Lecturer in 2007, Associate Professor in 2011 and Full Professor in 2019.  She has nearly 50 peer-reviewed articles and 3 books chapters on the topic of cannabinoid pharmacology dating back to 2004.  Her specific interests are on the therapeutic potential of cannabis-based medicines in cardiovascular disease, stroke, cancer, diabetes, and inflammatory bowel disease.  Her research methodologies span from cellular and animal models, to human healthy volunteer studies, systematic reviews and early phase clinical trials.  In 2016, she was named the International Cannabinoid Research Society Young Investigator of the Year.  In 2017, Saoirse set up an independent consulting company called CanPharmaConsulting Ltd, and through this, acts as scientific advisor to companies like Artelo Biosciences, CBDScience Group, Therapix Biosciences and Dragonfly Biosciences, helping to turn cannabinoid science into new medicines. She also develops educational tools around the use of cannabis-based medicines for higher learning institutes. She is a long-standing member of, and general secretary to, the International Cannabinoid Research Society. She works with charities, patient groups, healthcare professionals to educate on the benefits of cannabis-based medicines.  Saoirse has worked with the BBC and is an expert witness for the police.About Dr. Andy Yates, Ph.DDr. Andy Yates has more than 15 years experience in the pharmaceutical industry including 10 years as an executive at AstraZeneca. He held key roles within the medical affairs, commercial, business development and strategy functions for AstraZeneca's in-line and development portfolio. Dr Yates has been extensively involved in the life-cycle management of key multi-billion dollar products leading to the funding and initiation of significant development programmes. Whilst in business development he led evaluations and transactions that resulted in multiple collaborative agreements with academia, biotechnology and peer pharma. Dr. Yates is a UK registered pharmacist who received his PhD in cannabinoid medicinal chemistry from the University of Nottingham.QuotablesWhen I started in 2002, I thought it was complex, so I can't imagine what it's like for somebody coming into this area now, it is so complex. Cannabinoids work on so many different targets in our body. 06:00‘There will always be a group of people within the cannabis community who view synthetics as bad' 36:20ResourcesFollow Saoirse on LinkedIn: https://www.linkedin.com/in/professor-saoirse-o-sullivan-98b6bb53/Follow Andy on LinkedIn: https://www.linkedin.com/in/andy-yates-4985aa1/Follow Artelo Biosciences Twitter: https://twitter.com/ArteloBioArtelo Biosciences Website: https://artelobio.com/

This week we're delighted to be joined by Vera Twomey, mother of Ava (who suffers from Dravet Syndrome, a rare form of epilepsy), medical cannabis advocate, activist, and author of ‘For Ava...'.From the perspective of a mother and caregiver, Vera shares the difficulties and frustrations faced accessing cannabis in Ireland, the importance of access to medical cannabis for children, and the extreme lengths she went to to find medicine for her child.About VeraVera Twomey has spearheaded the campaign for access to medical cannabis in Ireland firstly on behalf of her daughter Ava Barry and subsequently on behalf of thousands who continue to seek access to medication for their family members.Vera's commitment and dedication to the advocacy for cannabis has become known across the UK Europe and North America. Vera has spoken within the House of Commons and The European parliament as well as all around the Rep of Ireland and Northern Ireland on the topic of medical cannabis.Her extraordinary book "For Ava" details the struggle and dedication she exhibited to achieve access to medication for her daughter. A regular speaker surrounding the issue of medical cannabis Vera Twomey can be credited with bringing the issue of cannabis into the public sphere in Ireland. Her exceptional determination and can-do attitude can be given significant credit for the positive changes made by the government to move the issue of cannabis in the Rep of Ireland forward.From Cork County in Ireland Vera lives with her family and continues to lobby tirelessly for fair access to cannabis medicine for all. → View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e103Quotables‘When we started on this journey we were so alone, we didn't know where to turn' 30:40‘I never intended to be known for issues surrounding cannabis, but when there are children involved… morally it is the right thing to do to share that with other parents to give them the opportunity to maybe find some improvement for their child's life' 31:17ResourcesJoin Vera on Twitter: https://twitter.com/veras1Buy Vera's Book: https://www.amazon.co.uk/Ava-incurable-reluctant-activist-campaign/dp/1781176833Dravet Syndrome UK: https://www.dravet.org.uk/

Nachdem wir in der letzten Woche genauer über das menschliche Endocannabinoid-System gesprochen haben. Stellen wir euch heute das erste und vermutlich bekannteste Phytocannabinoid vor. Delta-9-Tetrahydrocannabinol, kurz THC. Was bewirkt dieses Cannabinoid im menschlichen Körper, was für Nebenwirkungen hat es und wie kann es in der Medizin eingesetzt werden? All diese Fragen beantworten wir in dieser Folge! Wir freuen uns auf Kommentare von euch! Studien und Artikel: https://pubmed.ncbi.nlm.nih.gov/24407485/ https://www.medicalnewstoday.com/articles/323403 https://pubmed.ncbi.nlm.nih.gov/20590574/ https://www.medicalnewstoday.com/articles/322764 ✂- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Shop und Blog: https://hightere-gedanken.de/ wo wir noch zu finden sind: http://tree.hightere-gedanken.de ✂- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Ihr wollt uns finanziell unterstützen? Direkt bei PayPal: https://paypal.me/pools/campaign/112776516820811019 Den nächsten Amazon Einkauf über unseren Link (*): https://amzn.to/3sqklAU ✂- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - #highteregedanken #nutzhanf #cannabispodcast #aufklärung #pottcast #podcast ✂- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ►Unser Equipment im Überblick(*) Unsere DAW: https://amzn.to/3cLZmDn Für die DAW Steuerung: https://amzn.to/2LodjMF Audiointerface: https://amzn.to/2LRizYF https://amzn.to/38MqMGX Mikrofone: Rode: https://amzn.to/3sjV9fD https://amzn.to/2KhwxCS Cameras: GoPro: https://amzn.to/39uUq2z Canon: https://amzn.to/3bHG7dx Gimbal: https://amzn.to/3bCxz7H https://amzn.to/3bHGlRV https://amzn.to/3oHwgIw ✂- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ► Music by Smilez https://www.youtube.com/channel/UCWZwzh4yg-anvI19JCIlkNw (*)Bei diesen Links handelt es sich um Affiliate Links. Wenn ihr über diese Links etwas kauft, unterstützt ihr meine Arbeit, ohne dass es euch einen Cent mehr kostet – vielen Dank!

This week's show is a very special one for us - we're celebrating our 100th episode!In this show, we flip the script with one of our early guests - Thomas Gray from Lumino (formerly Blume Jobs) - interviewing Anuj.In this special episode Anuj reflects on what he's learnt over the last 100 episodes, how things are shaping up in the cannabis industry, and how he's looking to help people in this space. We'd like to take this opportunity to say a big thanks for all your support, and we look forward to sharing the next 100 episodes with you!→ View full show notes, summary, and access resources here: https://www.canverse.global/shownotes/e100About ThomasThomas Gray is a Co-founder and CEO of Lumino, a recruitment consultancy focused on exclusively aligning talent within the emerging European Cannabis Industry. With a background in founding and operating an NGO followed by working in financial services in the City. Thomas got involved in the cannabis industry in 2018 as a consultant for one of the early London based medical cannabis companies before founding Lumino (FKA Blume Jobs) in early 2019. Since inception, Lumino has supported clients across Medical, Business Ancillary and Plant Touching functions, in aligning specialised talent such as Master Growers, QP's, Specialist Doctors, Commercial Directors & Marketeers and many more industry specific roles. With sustained growth in the sector forecast, Thomas looks forward to welcoming more professionals to the industry in 2021 and being able to share Lumino's extensive insights with more innovative companies.Quotables‘It felt like an area which could really have a positive influence on the world, which is actually really what I Was looking for in life away from big companies. I was drawn to the challenge of overcoming the stigma that cannabis has' 06:10‘The last two years I've been doing this has felt a bit like an MBA - I've learned so much about businesses work and the world works' 13:20‘I'm really passionate about creating a better quality industry' 28:29There are lots of passionate advocates in the space but sometimes they can be too exuberant and blinkered about the wonderful benefits of cannabis 18:00ResourcesFollow Anuj on LinkedIn: https://www.linkedin.com/in/anujdes/Follow Thomas on LinkedIn: https://www.linkedin.com/in/thomas-c-s-gray/Follow The Cannabis Conversation on LinkedIn: https://www.linkedin.com/company/35533897/admin/Follow Lumino on LinkedIn: https://www.linkedin.com/company/lumino/Lumino Website: https://luminorecruit.com/Canverse Website: www.canverse.global

On this week's show we're joined by Kenzi Riboulet-Zemouli, drug policy advocate, leading researcher, president of FAAAT, and advisory board member of the European Industrial Hemp Association.Kenzi gives us a high-level overview of international drug control, including the treaties and conventions which manage it, and the politics involved. We also take a look at the recent historic removal of Cannabis from Schedule IV of the 1961 Single Convention on Narcotic Drugs.→ View full show notes and summary here: https://www.cannabis-conversation.com/blogs/episode93About KenziBased in Barcelona, Kenzi is a French-Algerian interdisciplinary researcher and advocate for sustainable drug policy reforms. He co-founded the French NGO NORML France and the think-tank FAAAT. Focused on Action research (matching scholars and citizens) as a catalyser for legal and social changes, Kenzi has been particularly involved in studying alternative pathways for Cannabis policy reform, linking international law with local grassroots initiatives. His work articulates around ethics, human rights aspects, fair trade components, and criteria of sustainability of legally-regulated use, production, and markets of internationally controlled and/or psychoactive plants, fungi, products or substances. Quotables[The vote] is the most powerful symbol that we have seen in drug policy so far and that we will see in the next decade 32:00ResourcesFollow Kenzi on LinkedIn: https://www.linkedin.com/in/teluobir/Follow Kenzi on Twitter: https://twitter.com/teluobir?lang=enKenzi's Website: https://kenzi.zemou.li/Join Kenzi on Patreon: https://www.patreon.com/teluobir

On today's show we're joined by the incredibly brave Michelle Kendall - advocate, medical cannabis patient and creator of documentary 'Schedule 1'. Michelle shares with us her incredible personal journey of using medical cannabis to manage ovarian cancer, including how a protocol of high dose THC shrunk the size of her tumour, kept her cancer in remission, and helped her manage symptoms. → View full show notes and summary here: https://www.cannabis-conversation.com/blogs/episode90About MichelleMichelle Kendall never expected to be a Cannabinoid Oncology pioneer, but after fighting terminal ovarian cancer for 5 years, that is where she landed.  3 years into her diagnosis she was introduced to Cannabis, and to her utter shock it shrank her tumour.  A passion for science led her to peer reviewed pre-clinical literature, where she was astonished by the anti tumour properties of Cannabis compounds.  Out of medical options, she hopes Cannabis will keep her in remission. QuotablesWe have to think of cannabis as a giant basket of pharmacology, there are 550 compounds, and it appears that so many of them are biologically pharmacologically active 26:35If I was a graduate student right now, I would be getting myself trained up in cannabinoid pharmacology as fast as I could - it's going to keep researchers busy for a decade 24:40The fact that we have to fight so hard for the science of something that is so groundbreaking and saving people's lives is just pathetic 25:35ResourcesWatch Schedule 1 Documentary: https://www.schedule1movie.com/Follow Schedule 1 Documentary on Instagram: https://www.instagram.com/schedule1movie/Follow Schedule 1 Documentary on Twitter: https://twitter.com/schedule1movie

Where did modern cannabis research start?This week we're honoured and privileged to be joined by the legendary Professor Raphael Mechoulam - heading up the Medical Chemistry department at the Hebrew University of Jerusalem. Dubbed ‘the godfather of cannabis research', Prof. Mechoulam has been a pioneer in the field, and over many decades has had a major influence on our understanding of the cannabis plant with his groundbreaking research and discoveries. In this very special episode of The Cannabis Conversation, we explore the history of cannabis research, alongside taking a detailed look at the function and physiology of the endocannabinoid system.→ View full show notes and summary here: https://www.cannabis-conversation.com/blogs/episode80About Prof. MechoulamDr. Raphael Mechoulam is an award-winning Israeli organic chemist who has been studying the cannabis plant for over 50 years. Dr. Mechoulam is best known for discovering the Endocannabinoid System and first isolating the two primary compounds, CBD and THC. He is a professor of Medicinal Chemistry at the Hebrew University of Jerusalem in Israel and has published over 350 scientific articles, primarily focused on the chemistry and pharmacology of Cannabinoids. His work has awarded him with many honors and awards, including the Israel Prize (2000), NIDA Discovery Award (2011) and many others.ResourcesProf. Raphael Mechoulam's Wikipedia Page: https://en.wikipedia.org/wiki/Raphael_Mechoulam‘Dr Raphael Mechoulam and his revolutionary cannabis research' - Article by Medical Cannabis Network:https://www.healtheuropa.eu/dr-raphael-mechoulam-revolutionary-cannabis-research/93049/‘Cannabinoid pharmacology: the first 66 years' paper by Roger G Pertwee: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1760722/

View full show notes here: https://www.cannabis-conversation.com/blogs/episode66This week we're joined by Mark Reinders, CEO of HempFlax Group who are the largest independent grower and processor of industrial hemp in Europe. Mark is also a board member for The European Industrial Hemp Association (EIHA).Together, we discuss the uses and applications of industrial hemp including its use in home insulation, as a bioplastic, and as a building material.About MarkMark is the CEO of HempFlax, Europe's largest independent hemp grower and processor. Mark has been at HempFlax since 2008 and was appointed CEO in 2016. HempFlax has operations across Europe, with over 2,400 hectares of hemp expected to be harvested in 2020.Raised in a farming family, Mark holds bachelor's degrees in agribusiness and crop production from Het Van Hall Instituut and a Master of Science degree in management from Nyenrode University.From 2016 to 2019, Mark served as president of the European Industrial Hemp Association, Europe's foremost coalition of the industrial hemp-processing industry. He continues to sit on its board of directors today.Episode SummaryHempFlax was founded in 1993 by Ben Dronkers with the aim of restoring the age-old crop to its former glory and reviving the industrial hemp industry. In the process, HempFlax has grown from 140 hectares of industrial hemp fibre in 1994 to 2500 hectares in 2017, in 2020 they expect to cultivate 3500 hectares. Their cultivation takes place in the Netherlands, Germany and Romania with their factories located in Oude Pekela, Netherlands and Alba Iulia, Romania.HempFlax are currently providing industrial hemp for use in car production to BMW, Mercedes, Bugatti, Jaguar and Bentley.Mark's father was a hemp farmer so he grew up around the crop. Mark strengthened this knowledge through interning at the company in 2000. It was in 2007 when Ben asked Mark to rejoin the team.Mark is a board member for EIHA, who are lobbying in Brussels for the recognition of Hemp amongst other activities. In The Netherlands, industrial hemp is prohibited unless it is grown for fibre and seeds, leaves and flowers are not allowed to be harvested. Across the border in Germany, this is allowed.New applications for industrial hemp are constantly being developed, it has an incredible amount of uses.It can be used as a construction material for houses, insulation, car parts, scooters, furniture and reusable cups.It can also be used as animal bedding or litter which is completely safe for animals and humans due to its lack of additives and minimal processing.The hemp plant thrives in almost any climate, it grows very quickly with little maintenance. No chemicals are required to grow it as it is resistant to pests and diseases.It consumes little water per kilo of fibre, much less than cotton, whose cultivation can be extremely harmful to the environment.Hemp also stores carbon dioxide during its growth, which is great for balancing the C02 levels in the environment.40% of the worldwide carbon dioxide emission is caused by construction and heating and cooling buildings. Traditional Fibreglass insulation is difficult to work with, it can be harmful to the skin and even inhaled. Hemp fibre on the other hand is non toxic and uses 10x less energy in its production than Fibreglass.HempFlax are also working within Bioplastics, by combining

Our guest, Dr. Roger Pertwee, has been studying cannabinoids for multiple decades. We discuss how cannabinoid therapy could work for PTSD, Pain & Multiple Sclerosis. Along with how different cannabis compounds can have an amplifying or dampening modulation effect on our Endocannabinoid System, impacting the effects we experience. Links to books mentioned, Handbook of Cannabis & Endocannabinoids Link to Join Email List Community for insights we don’t share anywhere else. Link to Periodic Contact Page

How and why has the status of cannabis changed over time?This week we're joined by the legendary Steve DeAngelo, internationally renowned cannabis activist and advocate who founded some of the biggest names in the business including The Arcview Group, Harborside Dispensaries and Steep Hill Labs.In this episode, Steve discusses why cannabis reform is finally happening, his non-profit campaign - The Last Prisoner Project, and why he believes cannabis will become the most valuable commodity in the world.

Learn about the basics of CBD and cannnabis, how it can improve your health, research supporting its health benefits, and why you could be using it wrong The information provided in or through this podcast, Website, blog, or newsletter is for educational and informational purposes only and solely as a self-help tool for your own use. Purchase CBD oil products: https://www.nutritionrewired.com/products Erin on WBZ radio: https://www.iheart.com/podcast/1002-jay-talking-28654274/episode/ketogenic-diet-52706673/ Erin on Vive Nutrition talking about CBD: https://podtail.com/podcast/vive-nutrition-radio/all-you-need-to-know-about-cbd-with-registered-die/ Erin on MOP Podcast talking CBD: https://podcasts.apple.com/us/podcast/009-the-truth-about-cbd-oil-with-erin-kenney/id1496203184?i=1000469821039 Russo, E.B. (2011). Taming THC: Potential Cannabis Synergy and Phytocannabinoid-terpenoid Entourage Effects. British Journal of Pharmacology, 163(7), 1344–1364. Gallily, R., Yekhtin, Z., Hanus, J.O. (2015) Overcoming the Bell-Shaped Dose-Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Pharmacology & Pharmacy, 6, 75–85. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120982/

How easy is it to protect your ideas in the cannabis industry?This week we are joined by Jane Hollywood (Senior Patent Attorney) and Robert Stephen (Partner) from CMS, International Law Firm. Listen in as we explore intellectual property in the cannabis space, delving into what intellectual property actually is,  which types of protection are available, and how to go about protecting your ideas.Episode SummaryIntellectual property is ‘something you create with your mind', this could be a story, an artistic work, a poem, a symbol etc.There are a number of different types including registered and unregistered rights, these differ with the type of material you have created. One of the main rights are patents which are registered rights intended to protect technical innovations or new solutions to a technical problem.Plant variety rights are able to protected for new and innovative varieties. Trademarks are also available for products or services which are attributed to a particular seller or retailer. Design rights and trade secrets are also protected. Registered property means you have to make an application with the relevant independent body. Registrations are only given if you meet certain criteria.Copyright is an unregistered right, and is automatically given when you create certain works.Intellectual property rights tend to be national rights, patents are given within certain geographical areas such as Great Britain or Germany. A patent gives the right to exclude, not practice. 18 months after you file a patent application, it is published.Within the cannabis industry, things like breeding and strains are kept as trade secrets.In terms of medical cannabis, products which have specific mentionable and innovative qualities such as a sustained release are able to be patented.It is difficult to patent a naturally occurring plant. Many farmers see patenting certain plants too strict as it makes it difficult to breed other varieties in the future. In the USA, plant patents are available with breeders exemptions. Plant variety rights only protect particular varieties whereas patents provide broader protection. Genetic sequences are not patentable unless there is a utility for it. The IP within the cannabis industry is comparable to the agriculture industry, there are no new developments within the industry regarding things that are ‘patent-able'.It is difficult to gain a trademark across the whole of the US for cannabis-related products. Jane and Rob suggest that if you are a business in the Cannabis space the best way to protect yourself is to first audit your services and/or products, identifying what you are doing differently. From there you need to work out what you have which is protectable and what other people within the niche are doing. There is a lot to be learned from competitors. ResourcesJoin Rob on LinkedIn: https://www.linkedin.com/in/robertjohnstephen/Join Jane on LinkedIn: https://www.linkedin.com/in/jane-hollywood-b3ab9315/CMS Website: https://cms.law/en/gbr/Cannabis and Intellectual Property article from Forbes: https://www.forbes.com/sites/kevinmurphy/2019/09/26/why-building-intellectual-property-in-the-cannabis-industry-is-so-difficult/#6206ae3e1fd

What does the FSA's announcement about CBD mean for the industry in the UK?This week we are joined by Dr Parveen Bhatharah and Dr Sarah Gaunt from The Association For The Cannabinoid Industry where they occupy the roles of Regulatory Lead and Global Regulatory Services Partner. Join us as we discuss the most recent updates to the Novel Foods Regulations by The Food Standards Agency. We explore what the new regulations mean for businesses who are currently operating within the CBD industry and for those who plan to in the future.Episode SummaryNovel Food Regulations are a European regulations which govern what can and can't be sold as a food product.Before the food can be legally marketed in the EU, novel foods are required to have a pre-market safety assessment and authorisation under the Novel Foods Regulation (Regulation (EU) No 2015/2283)The regulation applies to any food and food ingredient that hadn't been used in the EU for human consumption to a significant degree before May 1997. The food must also be either: food ingredients with a new or intentionally modified primary molecular structureCBD was introduced to the Novel Food Regulations only last year, meaning products which were on the market previous to the introduction did not necessarily undergo necessary safety assessments.On 13th February 2020, the FSA updated its rules around the retail of CBD products, making it clear that companies who already have products on the market will need to file a retrospective application by March 31st 2021 otherwise their products will be taken off the market.New products must go through the standard Novel Foods application, authorisation and approval, the same as any other foods on the market.Products which ‘break the rules' will have to deal with the Trading Standards Association, who have the power to remove products from the market.The Novel Foods Regulations apply to anyone who sells CBD products, regardless of if they are bought from a wholesaler, produced in-house, or white labelled.The person at the end of the supply chain who puts the product on the shelves (the seller) is ultimately responsible for making sure their products are safe.To file an application, you need to submit a dossier to The European Commission including data about the safety of your products, manufacturing practices and ingredients. Once your product is validated by the European Commission, it is passed on to the Food Standards Agency who conduct a risk assessment.The burden of responsibility falls mostly on the brands themselves who are supplying the manufactured goods and it is their responsibility to make sure their supply chains are transparent and following good manufacturing practice.Key safety studies must be carried out on raw ingredients, is it a brand responsibility to make sure that their suppliers are safe.Other examples of novel foods include Chia Seeds, which are a recent health food but were not historically in our diet or sold commercially.There are plans to launch a kitemark for CBD indicating quality and cannabinoid safety.ResourcesJoin The ACI on LinkedIn: https://www.linkedin.com/company/association-for-the-cannabinoid-industryAssociation For The Cannabinoid Industry Website: https://www.theaci.co.uk/Novel Foods Regulations Guide to CBD:https://www.food.gov.uk/business-guidance/cannabidiol-cbd

The benefits of CBD for your mental health are astounding. It has become a useful treatment protocol in conjunction with counseling, meditation, medication, and more. There is so much information out there but do you really know how it works? How it's formulated specifically for mental health benefits? Join geneticist Dr. Dave Vigerust, CEO and Forumulator Sanjeev Javia, and Orthopedic Surgeon, Dr. Jim Silliman, with Kristin to talk about this life changing addition to your mental health treatment. Sanjeev Javia has an undergraduate degree from the University Of Michigan in Biology and Biopsychology and a graduate degree in Business Administration from the Thunderbird School of Global Management. In addition to these educational certifications he frequently attends continued educational courses focusing on dietary supplement formulation, sales and marketing strategy development, and corporate development at institutions such as Harvard University, Arizona State University, Thunderbird School of Global Management, and Southwest School of Naturopathic Medicine. He has also completed his Aromatherapy, the medicinal use of essential oils, training at the Applied Aromatic Institute.Sanjeev began his nutritional and wellness career by becoming a partner at XELR8 Inc, a nutritional supplement company founded in Denver. The original business model was to develop a premier line of nutritional supplements exclusive to professional athletes and medical professionals. Sanjeev was responsible for all research and development of products and athlete acquisition. He developed 21 products at XELR8 which included energy and hydration drinks, protein powders, and an entire line of vitamins and minerals. XERL8 had 800 professional and Olympic athletes using their products and they were in at least 28% of the professional sports teams training and recovery rooms. XELR8 grew and then branched out from professional athletes and sold their products to retail channels such as GNC, High Health, and BodyBuilding.com, and Vitamin Cottage, and the network marketing channels.After the sale of XERL8, Sanjeev was asked to develop a Nutrition Science Center for the prestigious sports medicine and orthopedic group, Steadman Hawkins Clinic, in Greenville, South Carolina. The center was part of the Musculoskeletal Health and Wellness Institute at the Greenville Hospital System. At the Greenville Hospital System, Sanjeev assembled a team of nutritionist and performance coaches to compliment their 32 sports medicine an orthopedic surgeons and 45 physical therapists. He did research in the areas of Diabetes, Obesity, AutoImmune Diseases, and Neurological disorders. In addition to his research he further developed and headed the go to market strategy as President of a SpeedFlex Training, an exercise and therapy machine. In Greenville he directed 2 Childhood Obesity studies, 1 Parkinson and MS study, and wrote 4 research grants to the U.S Department of Defense in traumatic brain injury and elite exercise performance/conditioning.In 2010, Sanjeev founded Javia Wellness Group (JWG) in Scottsdale, AZ . Javia Wellness Group is a firm that is focused on bringing nutritional and wellness products and concepts to market for its clients. Leveraging Sanjeev’s experience in all critical areas of health and wellness, JWG is has been able to provide innovative solutions and ideas to those developing products or services in health related spaces. JWG has been able to develop, formulate, research, assist in manufacturing and co-packaging, and design entire sales and marketing strategies for their clients. With over 18 years of experience and the development of over 86 products in the performance, disease management, skin care, and popular areas such as weight management, JWG has provided turn key solutions.Sanjeev is also a sought after educational and research international speaker and frequent guests on radio and television. He is a continual speaker for the American Association of Orthopedic Surgeons, American Association of Naturopathic Physicians, and development groups such as Women’s Conversations. He also is a frequent guest on nutritional and wellness radio shows featuring Dr. Joel Wallach, Best Selling Author Jordan Rubin, and Nutritional Pharmacist Ben Fuchs.Dr. Jim Silliman has had an extensive career in healthcare as a practicing physician, Medical Director, hospital and physician administrator, and business development leader.A magna cum laude graduate of the University of Louisville Medical School, he completed his residency in Orthopedic Surgery at the University of Texas Southwestern Medical Center and completed fellowships in sports medicine and knee surgery in Lake Tahoe, California, and shoulder surgery, Vail Colorado. Dr. Silliman was also a Professor and Program Director of the Orthopedic Residency Program at UT Southwestern Medical Center.Dr. Silliman served as the Executive Director of the Steadman Hawkins Sports Medicine Foundation in Vail, and Senior Associate at the Steadman Hawkins Clinic where he managed every aspect of the business for one of the leading orthopedic surgery organizations in the world. While at Steadman Hawkins he was part of a team of Physicians caring for the Denver Broncos Football and Rockies Baseball organizations. He also served five years as a Team Physician for the U.S. Ski Team.Dr. Silliman served as the Program Medical Director of the Greenville Health System, currently Prisma Health, one of the largest hospital systems in the nation with 7 medical campuses, 15,000 employees, and 600 physicians. There he created the Musculoskeletal Health And Wellness Institute which included a team of 32 sports medicine physicians, 90 physical therapist, 12 performance coaches, over 50 athletic trainers and 10 nutritionist and dieticians. The center was the first of its kind pioneering in preventative and holistic medicine in the musculoskeletal practice of medicine.He is also founder and past President of the Hawkins Research Foundation, one the premier sports medicine research centers in the world.He also founded eMed Ventures, Inc., a venture capital firm that focused on emerging health care technologies that improved hospital and physician interaction and facility management and workflow.The last several years, Dr. Silliman has focused much of his work in the field of personalized medicine. Developing technologies and lab outcomes in the areas of pharmacogenetics and infectious disease testing to create better outcomes for patients.Dr. Silliman has served as a Chairman, Director and Advisor on numerous Boards of Directors. He is also a former member of the American Academy of Orthopedic Surgeons and the American Medical Association. Jim has given dozens of presentations in conferences and symposiums across America and has been published in a variety of peer-reviewed medical publications.www.proze.comProze offers a 20% discount on all of their formulations for Mental Health News Radio listeners. Use PROMO CODE: mentalhealth20

A series not just for Budtenders. THC has an impossibly wide range of medicinal benefits. However the right dose of THC mixed with other cannabis compounds for specific medical benefits is difficult to pinpoint. Another roadblock, most consumers assume THC is only responsible for the high/ euphoric effects. We’ll explore the exact bodily processes that THC can positively impact, in simple language that everyone can understand, to help you discover the true potential of this incredible molecule. Link to [Periodic Budtender Sessions] FB Group Paper Discussed [1] “Cannabis Pharmacology: The Usual Suspects and a Few Promising Leads” by Dr. Ethan Russo and Jahan Marcu Ph.D.

How easy is it to get a medical cannabis prescription in the UK?We're joined this week by Dr. Leon Barron, General Practitioner with a strong interest in medical cannabis, and founder of the Primary Care Cannabis Network - a platform for dialogue, debate and education to help further the conversation and strengthen the voice of UK GPs within medical cannabis.In this episode, we explore how medical cannabis could potentially be used in Primary Care within the NHS, the barriers faced when accessing medical cannabis, and the safety of cannabinoids for pain management.About Dr Leon BarronDr Barron is a GP based in London, UK.  His interests within General Practice include mental health and managing complex symptoms that often combine physical, psychological and social components. A holistic approach to his clinical practice has led to an interest in medical cannabis as an alternative therapy for patients who have not found conventional therapies to be effective.Dr Barron is an executive committee member of The Medical Cannabis Clinicians Society which provides high quality, balanced education and expert support to inform clinicians about the current state of evidence with regard to the efficacy of cannabis and its side effects. He is also the founder of The Primary Care Cannabis Network which offers a platform for GPs with an interest in medical cannabis. He continues to undertake regular NHS work and is a visiting tutor for undergraduate medicine at University College LondonEpisode SummaryDr Barron became interested in Medical Cannabis two years ago after hearing about cases in the media. At the same time, his relative in Israel was responding well to Medical Cannabis as a treatment which further sparked his interest.Leon explored the topic further by researching and finding scientific journals on PubMed where he came across the work of the early cannabis scientists.He identified ways in which medical cannabis could change clinical practice within the UK and then went on to meet a number of cannabis experts and specialists within the UK such as Mike Barnes who fuelled his interest.As of November 1st 2018, cannabis based drugs for medical use was made legal within the UK as prescribed by specialist doctors, by prescription only. GP's are not able to issue prescriptions.Leon encounters 2-3 patients per week in his general practice who ask about medical cannabis. He has also noticed a great interest from patients in CBD products.In the UK, the general view of practitioners is that a patient should have tried conventional therapies before being offered a cannabis based medication.For somebody who is experiencing pain, the first referral a patient would get (on the NHS) would be to a pain specialist, who are unlikely to prescribe cannabis based medication due to lack of knowledge. Another option is being seen privately, where the patient will have to fund the cost of the medication themselves, making this a dead end option for many. Another option would be to enrol in the 2021 trial which is being run by Drug Science. The aim is to enrol 20,000 patients by the end of 2021 and aims to create a body of evidence for the tolerability and effectiveness of medical cannabis. Medical cannabis in the UK is unlicensed, which some doctors see as a barrier to prescribing it. With this being said, unlicensed medicines are used across the NHS in many instances where there is no suitably licensed medicine which will meet the needs of the patients.Dr. Barron is a committee member for the UK Medical Cannabis Clinicians Society, an independent community of medical cannabis pioneers - the first prescribers of this

The Totally Well Show with host Joyce Strong, RN, BSN from www.TotalWellCoach.com and her guest Dr. Mary Jo MacKinnon from Skeeter's Wellness Company discussing the ABC's of CBD.   (Previously named Nanabis!)  Learn more about Skeeter's Wellness Company at SkeetersWellness@gmail.com.  Originally aired on www.thegrotonchannel.org in Groton MA.Totally Well is a place where we get curious, ask questions and explore everything to do with health, wellness, fitness, personal development, helping people and all the things it takes to help you live a strong, joyous life.I work with people 1-on-1 for powerful, life-changing transformation. I’m happy to offer a one-time FREE DISCOVERY CALL during which I will provide you with 3 recommendations to help you take immediate action on your health. In addition, we will explore key strategies for how we can work together to help you find your healthy place.Reach out to Coach Joyce at @TotalWellCoach on all social media platforms. I love getting questions and DMs and making new connections! What do you need help with? What problem are you trying to solve! Your questions help me produce great content to help more people!Subscribe and share my TotalWellCoach YouTube Channel to see the video version of Totally Well.ASK FOR HELP! ❤ Do you want to create a Strong Joyous Life?

What actually is pain and can cannabis help?We're back this week with an extended episode on the topic of cannabis and pain. This week we're joined by Dr. Matt Brown, an award-winning pain consultant based in London, UK. Dr. Brown takes a strong interest in the use of cannabis for the treatment of chronic pain and has recently published a piece of research into using cannabinoids for cancer pain treatment.Listen in as we discover exactly what pain is, how cannabis may be able to help us cope with it, and the future for medical cannabis in the UK.____________________________________About Dr. Matt BrownMatt Brown is a consultant and clinician scientist in pain medicine based in London. He trained at King's College London, winning the War Memorial and Wolfson Foundation Scholarships and graduating with distinction.His clinical training in pain medicine was conducted at The Royal National Orthopaedic Hospital and the National Hospital for Neurology and Neurosurgery. Matt fulfilled his long-term interest in clinical research by gaining a National Institute for Health Research's Academic Clinical Fellowship. This enabled him to conduct novel, award-winning research into pain at both Imperial College and King's College, London. Subsequently Matt completed a Doctorate in Medicine at the Institute of Cancer Research (becoming the first anaesthetist in the Institute's history to do so and winning the Chairman's Prize at graduation).Matt has published and lectured widely on the subject of pain. His research interests include cannabis medical products in pain, pain in cancer survivors, persistent post-surgical pain and chemotherapy-induced peripheral neuropathy (CIPN).________________________________________________Episode SummaryAs a consultant and researcher in pain medicine, Dr. Brown's clinical work sees him encountering many self-medicating patients who have turned cannabis for pain management. Dr. Brown sees is at the responsibility of a doctor to ensure that patient safety is safeguarded and protected, which is why he considers many of the approaches taken by the royal colleges very sensible. He is an advocate for more research into the side effects of cannabis as it is still largely misunderstood.As defined by The International Association For The Study of Pain - pain is an ‘unpleasant sensory or emotional experience associated with potential tissue damage or described in terms of such damage'Pain also encompasses emotional distress which can in turn impact mood and mental healthDr. Brown looks at pain through a biopsychosocial model which is the idea that having pain impacts your social life and your psychological wellbeing too. Pain is a far more complex than a simple sensory process. Early pain research based on simple physiological research but the biopsychosocial model was adopted in the 60's and 70's. It is estimated that around 20-40% of people in the UK have suffered from chronic pain at some point in their lives. This has a huge impact on our economy when you think about the number of days work lost from pain. The burden of pain within our society will increase with our ageing population and an increased rate of cancer survivors. The number of pain specialists in the UK is very small.Pain can affect us all very differently due to differentiating levels of psychological robustness.Med Tech such as wearable devices, AI and smartphones can disrupt the way in which medicine is practised as it gives you the ability to monitor people more closely.A problem with pain research is quantifying data - do you measure by a numerical rating scale? The measure of pain is largely anecdotal.

There was so much to chat about on this week's episode, that we've decided to break into a two-parter. We're lucky to be joined by Gregor Zorn, a medical cannabis educator and co-founder of the European Cannabinoid Therapy Association. Together, in Part 1, we investigate the challenges of trying to fit medical cannabis into the standard western medical system, explore the endocannabinoid system and how it interacts with the rest of the body, and look into the ways in which this remarkable plant can be integrated into western healthcare.If you'd like to find out more about Gregor, and for resources mentioned within the episode, click through to our show notes here: https://www.cannabis-conversation.com/blogs/episode31shownotes⠀⠀Episode SummaryGregor studied Biology at the Biotechnical University of Ljubljana and specialised in nutrition, as a result of this, he became interested in holistic approaches to health and in turn, discovered cannabis and its therapeutic potential. Gregor attended a symposium in Ljubljana which was attended by numerous doctors from across the world who spoke about using cannabinoids in order to treat human conditions. He found the conference incredibly interesting and was inspired to start reading medical journals around the subject. Throughout his research, he realised he was becoming more concerned with its therapeutic uses and started a mission to learn as much as possible around the subject. Once he had become an expert in the subject, he began teaching doctors and patients. Gregor is the co-founder of the European Cannabinoid Therapy Association, a medical cannabis educator for medical professionals, students, and patients.Western medicine relies heavily on the use of synthetic pharmaceutical drugs and surgery alongside other medical procedures. It is focused mainly on treating the symptoms of a disease rather than looking for the root itself. For example, if you have a headache you may take some paracetamol to stop the pain rather than treating the problem which caused the headache (a headache is a symptom, not a cause).A good treatment outcome comes from taking care of the cause of the symptoms, not the symptoms themselves. Many pharmaceutical drugs have side effects, which are in turn treated by more drugs which can present more symptoms. The cycle goes on and on. Pharmaceutical drugs may also have a reduced efficacy over time which means they are less effective the more you use them.Opioids are a good example of this, over time you have to increase the dose to achieve the same effects. This is due to their mechanism of action within the body - over time you become tolerant of them and need more to give you the same effect. Cannabinoid receptors are not found in the areas of the body which control your breathing, with no receptors, they cannot bind. This can be linked to the fact that you cannot overdose on cannabis or THC. Opioids have receptors in these areas, which allows somebody to be able to overdose. Different types of cannabis can be grown for different reasons, for example those with tall strong stems are grown for their fibres, those with lots of seeds are grown to make oils, and those with a high number of cannabinoids are grown for therapeutic effects.Trichomes store cannabinoids, terpenes (aromatic smells of cannabis) and terpenoids, which are found on the surface of the plant. The cannabis plant is different to other plants in the way that it produces its active ingredients on its surface unlike other plants who store their active ingredients inside the leaves, stems or flowers.Each of us have an endocannabinoid system, just like we have an immune system. This system generally speaking provides balance o

www.EvaWorldwide.com   Whole Plant Hemp Phytocannabinoid Therapy https://www.learntruehealth.com/phytocannabinoid Phytocannabinoid therapy can be significantly helpful if you’re looking into alternative ways of healing. I’m sure most of you have heard the benefits of hemp to address health issues. But surprisingly, whole plant hemp phytocannabinoid therapy can also heal pets. My guest Nicole Davidsohn has an exciting story to tell regarding phytocannabinoid therapy as well as educate us on the other healing benefits of this wonderful hemp herb. Series Of Accidents The Eva company story began in spring 2014 with a series of accidents. Eva founder Dane Kemp was in a near-death experience because of a car accident but still came to work. He did, however, suffer from post-concussion syndrome. His partner and co-founder Nicole Davidsohn, on the other hand, was diagnosed with ulcerative colitis. Doctors initially thought it was a stomach flu. Even with a flu protocol it never stopped. Nicole Davidsohn was misdiagnosed. It was only after a colonoscopy that she discovered she had ulcerative colitis. “The biggest thing I noticed with ulcerative colitis was fatigue. The way that it hurt my life was that I just wanted to sleep all day and I had no appetite,” shares Nicole Davidsohn. Before Nicole Davidsohn was diagnosed, she was a raw vegan. After her diagnosis, Nicole Davidsohn was prohibited by her doctor to eat raw foods and vegetables. So, she ate boiled chicken and sweet potatoes to get back on track. A few months later, Nicole Davidsohn fell on a flight of stairs. She ended up with misplaced ribs and extreme pain throughout her nervous system. Nicole Davidsohn still did a high-intensity workout class but felt worse after. Hence, she was rushed to the E.R., stopped going to work and eventually went into depression spiraled by her injuries. Health Struggle Weeks went by, and Nicole Davidsohn tried the medication the doctors gave her. The medicines were really strong which made Nicole Davidsohn sick. She slept a lot, avoided the sun and noise. Dane Kemp convinced her to move into their home in Baltimore so his mom could help take care of her, but Nicole Davidsohn’s condition didn’t improve. One night, Dane Kemp suggested to Nicole Davidsohn that they go to Oaksterdam University in California. He initially wanted to take their cannabis seminar on the history of growing. It was timely because, in 2015, the industry was beginning to open up. Availability Nicole Davidsohn says cannabis helped Dane Kemp in the past with attention issues. But on the East Coast, it’s not easy to get. Even if Nicole Davidsohn had a medical card for her ulcerative colitis, it limited her to two grams per day of the only strain they had which was blue dream. Blue Dream is a strain to get you thinking, be creative and invigorate your mind. “You can’t just smoke any cannabis and get relief from it because you have to have the correct ratio of cannabinoids and terpenes to help you with your specific ailment. In D.C., the dispensary you go to is dependent on your address,” Nicole Davidsohn said. Seeing An Opportunity Because of this, Dane Kemp saw an opportunity and also saw a way to help people. Taking a seminar at Oaksterdam University, the couple learned so much about cannabis, cannabinoids, growing it, its history, starting a business, and learning about the industry. Nicole Davidsohn also called up an old friend in California who gave her a bag of medical cannabis goodies like edibles, vapes, and joints including a type of caramel popcorn which contained THC. It was the first time she used cannabis as real medicine. Nicole Davidsohn ate the popcorn at night and slept well. It did have Tetrahydrocannabinol or THC in it, but she wasn’t high when she went to class. Instead, she just used it after class. The THC popcorn ultimately made Nicole Davidsohn feel better. Going back home to the East Coast, the couple did some preparations to move back to the West Coast to start a new life and begin healing holistically. Cannabis Juice When Nicole Davidsohn was in California, she had been studying the work of Dr. William Courtney who was famous for cannabis juice. She eventually wanted to grow her own vegan cannabis plant and juice it. “So, I bought an aero garden, planted some seeds and started growing cannabis like a normal herb on the counter. When it was big enough, I stuck it in my juicer with some turmeric and ginger. It tasted great,” said Nicole Davidsohn. Cannabis has acidic cannabinoids in its raw form. THC is THC-A, so it has a carbon molecule on it. Nicole Davidsohn says that for it to become psychoactive, or to make you feel high, you need to heat it to 220 degrees Fahrenheit for a certain amount of time. “When you juice it, just like you would go outside and take a fresh apple off a tree, chop it up and put in your juicer. I would take the bud off the plant and put in the juicer,” Nicole Davidsohn said. “It extracts all the cannabinoids, terpenes and chlorophyll which is super healthy for you. You won’t get stoned.” Effects of Juicing First thing Nicole Davidsohn felt was that her eyes widened, and her brain cleared up. It gave her four to six hours of energy. One reason is that raw cannabis is full of nutrients. It’s also a complete protein with all the essential amino acids. It has a ton of vitamins and minerals, too. “The reason why I started juicing was to help my brain recover, but it was also to help get my colitis back in remission,” revealed Nicole Davidsohn. “I think because I needed the nutrients, it started to slow my digestion and bring my body back to homeostasis instead of an inflamed state. It didn’t heal my post-concussion syndrome. I went to speech therapy for that.” She adds, “Juicing is not the easiest thing in the world. I juice three times a week. But once I made a container of it, it last three days unless you vacuum seal it then it will last seven days. I wasn’t consistent at first. For the first year, I was juicing every month and taking other cannabinoids as well.” Birth Of Eva Starting the company Eva, they began as the first 100% comprehensively lab-tested dispensary delivery in Sonoma County. Both Dane Kemp and Nicole Davidsohn got familiar with the certificate of analysis on everything. Eventually, Eva was the only dispensary in California in 2015 to have their menu comprehensively third-party lab-tested. “The juice inspired the capsules that we have. I made one called Better Brain which has Bacopa, Matcha and the whole hemp plant flower in it. The speech therapy plus the juice and Better Brain capsules helped my brain to heal,” revealed Nicole Davidsohn. Mary The Dog Mary was Nicole Davidsohn’s a Pit/Dalmatian mix who received a terminal lymphoma diagnosis in October 2016. She was given three months to live with or without chemotherapy. Nicole Davidsohn was making the juice at the time and helping people with assorted health ailments. So, she thought of giving Mary the juice by incorporating it in her food. It was not long before Mary went from being fatigued to energized. “We also bought some CBD oils and mixed it with the whole plant. They were raw oils. But Mary did not respond the same way compared to when she was given the juice,” recalled Nicole Davidsohn. “I think because the oil is fat-soluble, and it takes a lot longer to digest and be absorbed.” Nicole Davidsohn continued to give Mary the juice with turmeric and ginger. The dog continued to stay energized and didn’t get sick. After Eva company developed Better Pet Relief for Mary’s cancer and arthritis, Mary’s cancer has gone into remission. The capsules also help manage Mary’s arthritis. Aside from this, Nicole Davidsohn also adds a little bit of black pepper extract into Mary’s diet to help in the absorption. Compatibility With Hemp Nicole Davidsohn explains that we have an endocannabinoid system. Endo means inside. We already have receptors and cannabinoids in our body. And cannabinoids are also found in the plant cannabis. But when we’re stressed out, we make fewer cannabinoids naturally. “When we take in external cannabinoids from hemp or cannabis, it’s like getting a multivitamin. So, it’s fulfilling that deficiency. I like to think of it as vitamins,” said Nicole Davidsohn. “When I think of the endocannabinoid system, I think like it’s just another set of receptors for a vitamin that we aren’t taking any more.” She adds, “I believe we have an epidemic of what I call endocannabinoid deficiency syndrome. When people are deficient in making their natural cannabinoids, they feel so much better when they ingest CBD oil, Eva CBD capsules or edibles.” Dementia First of all, Nicole Davidsohn says their capsules can’t cure, treat or manage any disease. For dementia, in particular, she suggests their product, Better Brain. Nicole Davidsohn also revealed that the element Bacopa was used in Ayurvedic medicine for thousands of years for dementia and there are studies behind it. But cannabis can also do that. All of Eva’s capsules contain whole flowers, so everything is raw. And it is made of organic hemp flowers. It aims to clear the brain and give you that phytocannabinoid nutrient in case you’re deficient in it which could also be causing memory loss. Nicole Davidsohn again assures everyone that the capsules will not get you stoned. Dosage According to Nicole Davidsohn, the capsules are formulated to last four hours. If you’re looking to last an entire day of super brain power, Nicole Davidsohn recommends taking one capsule when you wake up and another one in the afternoon. “The formulas are based on research I did to find the best dose of Bacopa, cannabinoids, and Matcha green tea,” Nicole Davidsohn said. “Bacopa is also an adaptogenic stress reliever. People use it for stress relief, and they also use it for pain relief.” Panic Attacks For panic attacks, Nicole Davidsohn highly suggests their Better Mood product. It contains Valerian Root, Lemon Balm, and Hemp. A little dose of Valerian Root helps you calm down. It’s used for insomnia, anxiety and increase GABA receptors. Nicole Davidsohn says Lemon Balm is safe even for kids. Many kids take Lemon Balm for anxiety and focus. Pain Medication Addiction Nicole Davidsohn says their formula may help someone with a pain medication addiction by employing phytocannabinoid therapy. As a person tapers off the hard pain drugs, Nicole Davidsohn suggests taking Better Relief Capsules. However, it is advisable to work with a doctor to help taper off the medications and increase the intake of raw cannabinoids with turmeric and ginger. “Many studies have shown how CBD and whole plant hemp can reduce the side effects of withdrawal by nourishing the endocannabinoid system,” said Nicole Davidsohn. “If we’re able to supplement the body with phytocannabinoids, it would help people get off pain medications more quickly.” Eva’s products are also safe for children because it is non-psychoactive. Nicole Davidsohn says all their capsules are whole herbs, whole plants, and raw vegan. Better Brain and Better Mood Capsules can help children focus better and address their emotional issues like anxiety. Nicole Davidsohn also says that one of the big things that children can benefit from phytocannabinoid therapy is to help them reduce toxin overload.  Full Spectrum Full Spectrum would be including all of the cannabinoids and the naturally present terpenes in the plant. Nicole Davidsohn says you can get a Full Spectrum extract which would be using the whole plant. “Take a whole hemp flower, put it in some olive oil, shut it and put it in a dark place. Shake it once every day. Leave it in the dark cupboard for two weeks,” advises Nicole Davidsohn. “Then strain the oil out from the flower, and now you have a Full Spectrum Tincture.” Full Spectrum means it contains all of the cannabinoids and all of the terpenes that are naturally present in the plant. Nicole Davidsohn reveals that their company uses therapeutic hemp, specifically grown to be phytocannabinoid-rich, organic and does not have any contaminants in it. Eva Products There have been many success stories of people who have benefitted from cannabis juice and Eva’s products. Other worthy products to check out from the Eva website is Better Sleep and Better Pet Relief. As mentioned previously, Better Pet Relief helped Nicole Davidsohn’s dog get on the road to recovery.  Contest I’m thrilled to announce that Nicole Davidsohn is generously giving away ten bottles of Eva’s herbal supplements. Go to the Learn True Health Facebook group to find out how you can win. Each of the ten winners will have the chance to choose the formula of their preference so make sure you check out our group.  Eva is also giving a 20% discount to Learn True Health listeners. Just type in the LTH discount code upon checkout at the Eva website. “I am grateful being on a podcast speaking about Eva, our goals and our passion and our love for the world. And I’m grateful for this show and listeners who listen with an open mind and are here to learn. The goal is to have a happier and healthier world than where we are now,” said Nicole Davidsohn. Bio Nicole Davidsohn was born in Los Angeles, CA and raised in Lancaster, CA.  She grew up the youngest of 4 becoming the first in her family to attend college at Antelope Valley Community College before transferring to UC Irvine on a full scholarship.   Nicole Davidsohn received her BA in Psychology in 2011 and later received national certifications in personal training and nutrition consoling. In 2015, she left the world of personal training and fitness to attend Oaksterdam University before moving west to start Eva with Dane Kemp. Get Connected With Nicole Davidsohn! 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VITALIBIS, INC. (OTC: VCBD), a technology based formulator of premium, full spectrum phyto-cannabinoid rich (PCR) products, along with safe personal care and certified organic nutritional products, today announced a letter to shareholders from the Company's President and CEO, Steven Raack, to provide an update on the Company's business activities.Dear fellow shareholder:For the last 2 quarters of 2018 we have engaged in a new chapter for Vitalibis. We moved from a “Vitalibis endeavors…” to a “Vitalibis is…” company. During the last 6 months many things have kicked off.Phase 1, version 1 of our website launchedOur first two wellness products landed in our warehouse and began shippingOur first batch of full spectrum, Phytocannabinoid rich (PCR) powder shippedWe began selling product through our Professional ProgramOur Ambassador Program launched and our numbers are growingWe achieved 2 consecutive quarters with increasing revenue.Our social mission in all 4 categories of AIR LAND WATER PEOPLE launchedOur Regional Sales Managers are engaging new Ambassadors and customersIt was a great thing to experience. All of our technology investment including Order, Ship and Pay processes worked with relatively no glitches. Whew. Great appreciation to all of our team members for making everything happen.For additional information, www.vitalibis.com This episode is brought to you via Stock Wave - a production company that provides audio & video services to variety of clients. Stock Wave may have been compensated for the production of this audio service.In trading, there can be no assurance that any prior successes or past results as to income earnings can be used as an indication of future success or results. Audio/video services by Stock Wave are for informational purposes only and do not purport to be a complete study of the featured company or other companies mentioned. Information used and statements of fact have been obtained from the featured company and other sources, but not verified nor guaranteed by Stock Wave, as to completeness or accuracy. Listeners are advised to use caution and seek the advice of qualified professionals before acting on any information provided by Stock Wave’s audio/video services. Listeners are also advised to perform their own due diligence when it comes to making investment decisions.

Artikel lesen: https://www.hanf-magazin.com/medizin/cannabinoide/anandamid-unser-organismus-kifft/ Dem THC sehr ähnliches endogenes Cannabinoid Beim Cannabis denken viele zuerst einmal an Kiffen und High sein. Dabei ist dieses High als Rauschwirkung auf ein einziges Phytocannabinoid zurück zu führen. Alle anderen Phytocannabinoide beeinflussen höchstens dieses High vom THC, machen für sich alleine jedoch nicht high. Beim Cannabis und den Cannabinoiden kann jedoch auch an das Endocannabinoid-System gedacht werden. Hier werden körpereigene Cannabinoide als sogenannte Endocannabinoide ausgeschüttet. Anandamid war das erste im Jahr 1992 entdeckte endogene Cannabinoid. Es ist dem Delta-9-THC sehr ähnlich. Kifft unser Körper?

Kate and Don interview Julianna Carella, CEO and Founder of Treatibles and Auntie Dolores. We discuss the use of hemp-derived phytocannabinoid nutraceuticals and their ability to offer dogs relief from anxiety, arthritis, pain, inflammation, seizures, nausea, motion sickness and even their ability to help those with cancer. We discuss the science behind these products, their safety, and what one should look for when selecting a Phytocannabinoid Nutraceutical for their pet.