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#235 'Diced, Sliced and and Spliced the latest episode of aural torture from Anointing The Sick is now available to download. Kicking off with one of last years entries into the Doom Charts, the doomgaze of Troy The Band and finishing with stoners Snowburner. In between there are plenty of Name Your Price albums you can pick up from bandcamp, a bountiful harvest from the metal filth pit and a highlight of the year so far from sludgsters Negative 13.~Embrace The Sickness of ~Troy The Band #13 Feb 2024 Doom ChartsStrikerSinistrumRattenGhoulLas TrumienPissing RazorsNegative 13Wildweed NYP BandcampJunior Bruce NYP BandcampSun Preachers NYP BandcampWarpflesh NYP BandcampRot Away NYP BandcampBlind Effect NYP BandcampEartheater NYP BandcampSnowburner
VP Kamala Harris did a sit down interview with CBS's 60 Minutes over the weekend. The program proceeded to edit Harris's answers. They don't even make it look like they're objective. Help For Hurricane Helene victims: https://www.samaritanspurse.org Freedom Marketplace: https://freedommarketplace.net Join our Inner Circle: http://toddhuffshow.com/join Sign up for our newsletter: https://www.toddhuffshow.com Stack of Stuff: https://www.toddhuffshow.com/stack-of-stuff Email: todd@toddhuffshow.comPhone: 317.210.2830Follow us on…Instagram: @toddhuffshowFacebook: The Todd Huff ShowTwitter: @toddhuffshowLinkedIn: The Todd Huff ShowTikTok: @toddhuffshowSupport Our Partners:https://www.toddhuffshow.com/partners Links:https://www.mypillow.com/todd Promo Code: TODDhttps://mystore.com/toddhttps://faith-lit.com Promo Code: TODD for 15% offhttps://harvardgoldgroup.com Promo Code: TODD for $250 credithttps://www.nicnac.com - Promo Code TODD for 15% off your first purchasehttps://soltea.com - Promo Code TODD for $29.95 off your first orderhttps://zstacklife.com/todd - Promo Code TODD for 15% off your order
VP Kamala Harris did a sit down interview with CBS's 60 Minutes over the weekend. The program proceeded to edit Harris's answers. They don't even make it look like they're objective. Help For Hurricane Helene victims: https://www.samaritanspurse.org Freedom Marketplace: https://freedommarketplace.net Join our Inner Circle: http://toddhuffshow.com/join Sign up for our newsletter: https://www.toddhuffshow.com Stack of Stuff: https://www.toddhuffshow.com/stack-of-stuff Email: todd@toddhuffshow.comPhone: 317.210.2830Follow us on…Instagram: @toddhuffshowFacebook: The Todd Huff ShowTwitter: @toddhuffshowLinkedIn: The Todd Huff ShowTikTok: @toddhuffshowSupport Our Partners:https://www.toddhuffshow.com/partners Links:https://www.mypillow.com/todd Promo Code: TODDhttps://mystore.com/toddhttps://faith-lit.com Promo Code: TODD for 15% offhttps://harvardgoldgroup.com Promo Code: TODD for $250 credithttps://www.nicnac.com - Promo Code TODD for 15% off your first purchasehttps://soltea.com - Promo Code TODD for $29.95 off your first orderhttps://zstacklife.com/todd - Promo Code TODD for 15% off your order
Spliced by Brothers-In-Crime 01. Dua Lipa - Houdini 02. Diplo & Riva Starr ft. Karen Lomax - Heaven Or Not 03. Paul Russell - Lil Boo Thang 04. Becky Hill - Outside Of Love 05. Blessed Madonna ft. Clementine Douglas - Happier 06. Majestic, Jammin Kid & Celine Dion - Set My Heart Of Fire 07. Dua Lipa - Training Season 08. Galantis, David Guetta & 5 Seconds Of Summer - Lighter 09. Eliza Rose & Calvin Harris - Body Moving 10. Dua Lipa - Illusion 11. Ariana Grande - Yes, And? 12. Calvin Harris & Rag 'N' Bone Man - Lovers In Past Life 13. Badger & Natasha Bedingfield - These Words 14. Kygo w/ Ava Max - Whatever 15. Olly Alexander - Dizzy 16. Tate McRae - Exes 17. Teddy Swims - Lose Control 18. Sophie Ellis-Bextor - Murder On The Dancefloor 19. David Guetta & OneRepublic - I Don't Wanna Wait 20. Nathan Dawe - We Ain't Here For Long 21. Tate McRae - Greedy 22. Billy Gillies ft. Hannah Boleyn - DNA 23. NewEra - Birds In The Sky 24. Becky Hill - Never Be Alone 25. Cassö, RAYE & D-Block Europle - Prada MORE PLAYHOUSE ▶️ bit.ly/RA_PLAYHOUSE reactivateasia.com FIND US ON OUR SOCIALS! FACEBOOK
Join us in this episode as we sit down with Leo Segovio, a top expert in the space, to discuss a wide range of topics that are essential for E-commerce sellers. Leo shares his unique insights on how optimizing Amazon images can significantly impact indexing and ranking. He also opens up about his recent ventures, including a software project for influencer and affiliate marketing, and an intriguing Airbnb project in Italy. Additionally, Leo provides valuable tips for Amazon sellers looking to diversify their income by investing in real estate, highlighting the importance of strategic investments to complement a thriving Amazon business. Listen in as we explore the evolving landscape of influencer and affiliate marketing strategies. We discuss how leveraging platforms like TikTok, Instagram, and YouTube can empower brands by building robust affiliate networks. We highlight successful brands and share advanced techniques for optimizing listings to ensure better visibility on Google and Amazon. Practical tips for using press releases on high-authority domains to improve Google indexing are also discussed, offering listeners actionable advice to enhance their marketing efforts. Finally, we talk about the significance of Google indexing for Amazon sellers and the benefits of driving traffic from Google to boost Amazon rankings. We discuss the theory that paid traffic may hold more weight and the value of optimizing images with keywords to enhance discoverability. Additionally, we examine Amazon's evolving search algorithms and how intent-based optimization is changing the way products are discovered on the platform. This episode is packed with valuable insights and strategies to help Amazon sellers navigate the complexities of e-commerce and achieve greater success. In episode 568 of the Serious Sellers Podcast, Bradley and Leo discuss: 04:14 - Investing In Real Estate Investments 09:41 - Leveraging Creator Marketplace for Affiliate Networks 15:56 - Google Indexing for Amazon Sellers 18:16 - Google Traffic Boosts Amazon Ranking 24:01 - Google Indexing Boosts Product Visibility 26:46 - Search Algorithm Evolution and Intent-Based Optimization 29:13 - Optimizing Amazon Listings for Intent-Based Search Transcript Bradley Sutton: Today we've got one of the top minds in the entire Amazon game back on the show, Leo Segovia. He's going to be talking about a wide variety of topics, such as the impact on indexing and ranking by optimizing your Amazon images, and much, much more. How cool is that? Pretty cool, I think. Bradley Sutton: Hello everybody, welcome to another episode of the Serious Sellers Podcast by Helium 10. I'm your host, Bradley Sutton, and this is the show. That's a completely BS-free, unscripted and unrehearsed organic conversation about serious strategies for serious sellers of any level in the e-commerce world. And speaking of the e-commerce world, I'm on the other side of the world right now. For those of you listening, maybe I sound a little different. We are in the AVASK office here in Madrid, Spain, right in the middle of our Elite Workshop, and just about 15 minutes ago we had our very first speaker. All the other speakers are very mad at him because he started off and he set the bar really high with his talk, but we've got no stranger to the show, Leo Segovia. Leo, how's it going? Leo: Bradley, good morning. How are you doing? Bradley Sutton: Doing great, doing great. Leo: Awesome. Yeah, this morning was great. I'm actually happy this is my first time in Madrid. Yes, I actually just stopped once. I think I was on my way to Puerto Rico, but yes, I got to enjoy the city. Today I'm here at the AVASK office in Madrid, so happy to be here and happy to be your guest again. Bradley Sutton: Awesome, awesome. So now you know it's been a while since Leo's been on the show, so let's first just catch up with what you've been up to. Have you been launching products on Amazon? You've just been focused on building software. What have you been up to the last couple of years since you've been on the show? Leo: Yeah, it's been a crazy year for me actually. I've been involved in a couple of different projects. We are obviously always looking for new products to launch. What kept me very busy in the past year has been software that I've been working on for influencer and affiliate marketing, and actually this Airbnb project in the south of Italy, which has been kind of a roller coaster. Yeah. Bradley Sutton: So, you actually moved, I remember you went from Canada to Florida and then a few months ago you moved back to your home, uh, country of Italy, but then this was always meant to be kind of just like a like a winter, uh or summer home for you. Leo: Yeah, that is correct. Uh, I have a family in Italy. So, and recently their area of Italy is called Puglia, it's in the southeast was becoming more and more popular and more expensive, and so I decided to buy a property there so that we could spend a week or a month in the summertime, perhaps, when in Florida is too hot, you know, go inside of Italy. Invite some of my Amazon friends, you know, mastermind, and so that's the plan. Now, I was supposed to be there only for a couple of months, just to see what was going on, but when I got the keys, I realized that the place needed a lot of work, and so I've been stuck in Italy since November, actually, of last year, and I'll probably stay there until for two more months before going back to Miami. Bradley Sutton: What passport do you have? What country passports? I have Italian and Canadian passport. Okay, so then, when you bought this house, you use your like Italian citizenship? Leo: No, actually I well, I could participate to an auction because I bought this place at an auction. Not the $1 ones, it was more than that. But yes, because of my Italian citizenship it allowed me to participate to an auction. But everything that I'm doing is as a Canadian citizen. It works out better from tax perspective and all that. Bradley Sutton: Okay. So that's why I was asking about this, because I think this is, you know, like somebody might be jumping on the show. What are we talking about? Airbnb here? But as e-commerce entrepreneurs, Amazon sellers, maybe we make a little money, maybe we're not interested in exiting our business, but now we have extra money, like do we start other businesses? You know, maybe something that has nothing to do with Amazon, but I hear of more Amazon sellers doing something similar. Where they go you know, not necessarily Italy, but another country, buy a house and then so, as a Canadian citizen or as an American citizen I would assume it's about the same. What's the process of participating, like in this Italian auction to be able to buy this house? Leo: I think you need to have someone in Italy or a friend, someone with an Italian citizenship, in order to buy a place at auction. Otherwise, you just have to go to a real estate agent and buy a regular place. The reason for me it was convenient is because it was a good deal. If I was able to win the auction, and so in real estate, you make money when you buy, not when you sell. Right, if you buy for less, that's most likely guaranteed revenue or earnings whenever you sell, and so that's the reason why I did this. Now, I don't know exactly the process if I didn't have any Italian citizenship, but yeah, a lot of entrepreneurs you know, especially Amazon sellers whether, when they exit or you know if they're already doing quite well and they have good cashflow, they normally tend to invest in real estate Airbnb's. You secure yourself passive income from that, and it's always a good investment. Bradley Sutton: So then would I have to have all cash though to once the auction closed, I can finance over there. Leo: Okay. So that's an interesting thing. I was going to finance the project. I ended up buying a cash because it just made more sense for me, but in Italy they actually give you a mortgage as long as you can prove that you have income outside of Italy. Bradley Sutton: Okay. And then so you calculated out, like how much you can maybe get an Airbnb. And then so have you calculated hey, for the other months of the year where I'm not staying here, I need to rent this place out x amount of time of the year. And it's going to be worth it, have you like, and did that analysis? Leo: Yeah, so in this specific region of Italy and the location of what I bought in August for a place with a pool and four or five bedrooms, you can charge 5,000 to 6,000 euros a week. So you make your money in the summertime. Ideally, as an investor, you don't want to go and spend time in the summertime there, but you want to go, perhaps either early, like May or September, when the season starts to kind of slow down and so you don't take out money from your profits, right? So my plan is to rent it out June, July and August. If I have some good offers in September, maybe I'll rent it out, otherwise I'll go myself there in September or May, but, yeah, normally throughout the year. Leo: You know Italy is a destination where you have a lot of tourism during summertime, unless you're in Rome or Venice or Florence, which is always busy throughout the year. You know south it's a summer destination, right. So you get a lot of tourism summertime. Wintertime dies down, so you probably can get us or what you can get in the summer. But you know it works out well because if you have a small apartment, for example, in a big city, and you are charging, you know, 200, 300 a night? Um, at the end of the year you make the same money. So with this kind of properties is a little bit of a different um investment. I went more on the luxury kind of market, hoping to work only with Americans. You know foreign tourism, but in my opinion it's a great one. Bradley Sutton: Okay, so there you have it, guys. You know, like, maybe you've had some success on Amazon and you're thinking of what kind of things to invest in. You know, getting a property at a low price and maybe fixing it up even though it's a headache a little bit, you know could be the route that you want to go. Now you know we're going to talk a lot about some really cool Amazon strategy coming up, but you've been developing some software lately for a while now. That's not necessarily for on Amazon, but it helps Amazon sellers. Can you talk about that a little bit? Leo: Yeah, I've been working. The software is called Spliced. I've been working on this for about two years now and I was supposed to be already in market, and the reason why I'm late is because of what I just explained. It took me, you know, it took resources and energy a little bit off the other project, but now we're ready to go, and the reason why I built this software is, you know, Bradley, you know I have Convomat, which was my first software that I built, and then Amazon changed it to iOS, and so I had to find a way to pivot. But I already knew that influencer and affiliate marketing was the way to go, also for us Amazon sellers, in order to have a little bit more control over the traffic, over the business and the revenue that we drive to our brands. And so, with Spliced, my goal is to leverage the creator's marketplace, which is huge between TikTok and Instagram and YouTube, and leverage that to build affiliate networks for your own brand. Leo: There are already a lot of sellers out there that are doing a good job when it comes to affiliate marketing. Look at a brand like Goalie. Goalie, one of the key strategies for Goalie was actually the affiliate marketing, and so with Spliced, my goal is to allow brands to look up into our marketplace, which has already been built with we have over 20 million creators and then approach them with an affiliate partnership instead of just UGC content. This is the reason why we didn't build in Spliced, just UGC campaigns. There's already plenty out there of softwares that you can use for UGC, but in my opinion, if you have a solid affiliate network, you can keep launching new products, relaunching the same products. We use it for reviews. If you need something like that and you have more control over your business, and if you decide to launch your D2C website, you can leverage the same network and start pushing traffic off of Amazon. So there are a lot of reasons why I believe people should use a platform like that. It's like building an email list, but instead you're actually leveraging the creator marketplace. Bradley Sutton: Okay, yeah, interesting, I think TikTok how it works, people's eyes are really open to more of influencer marketing. I mean, it's basically influencer marketing. There's not really SEO on TikTok, or it's not even. Even if you understand the hashtags, it doesn't necessarily guarantee the rally. It's a numbers game like getting you know. You get out to 25 influencers and maybe 24 do nothing, and then one person, even though they're small, they get on the For you page or something like that and literally can bring thousands and thousands of dollars. There's somebody I've been helping with, you know, shipping their products and they're you know they're doing me sometimes some days a thousand fifteen hundred units of sales for like this planner and it was a hundred. They didn't spend any for PPC on TikTok 100%. You know they just push the product to influencers and then one here and one there just goes viral and it just means a lot of business. Leo: Yeah, I think you know it's probably right now a big hype. I mean the TikTok shops everyone is talking about them working with affiliates and it's probably one of the oldest marketing strategies, if we want to call it that way. You know the affiliate marketing works because of the power that the individual creator in this case has to influence people right, and so people want to buy from people, and if you, as a brand, do a good job in recruiting a few super affiliates in this case we're talking about good creators that will turn into affiliates, then you have to worry less about that promotion part of you know launching new products. Bradley Sutton: Interesting, interesting. Okay, now let's move a little bit back towards the Amazon world and actually I'm going to go a little bit off of Amazon, but it's something that you talked about today in your speech and we're not going to go too deep into it. If you guys want to really hear his presentation, you have to be an Elite member. So you Elite members definitely make sure to look out for the recording on that. But one thing you were talking about when it comes to images, but the way you discovered this was you said you were checking indexing on Google. So we know, on Amazon, if you want to check indexing, you just use Helium 10 index checker, right? Or if you don't have Helium 10, you can use the old school method of put the ASIN plus the keyword and then search and see if it comes up. For just rudimentary index checking for keywords. If you want to see if your Amazon product is indexed on Google, how do you even see if you are? Leo: Yeah, so normally on Google you will copy your URL, search it on Google. You can also do a site column with your URL and then Google will show only search results that are related to the domain you're searching. But if you type the whole domain, the whole URL, the canonical URL of your Amazon listing, if you are indexed, it will show there. Bradley Sutton: But what about if you're? Can you look if you're indexed for a specific keyword? Leo: So if you're indexed for a specific keyword, then you want to put that URL plus the keyword and then or amazon.com/dp/your ASIN, or you can also do ASIN in quotes plus the keyword and then you will see if you get, if you're indexed on Google from that keyword. It works in a similar way. Um, but yeah, the presentation we touched a lot on you know the details of what was going on Google which was dependent on, uh, the way that the listing was optimized on Amazon. Bradley Sutton: You talked about some advanced strategy. We'll talk a little bit about that, about like images and stuff. But without the images, is there a way to force yourself to be indexed on Google, like, for example, if you create a custom canonical URL, just insert the keywords and then if you actually happen to you know, like maybe run some Google ads, get some conversions on that, will that index you for that keyword on Google? Leo: Yeah, so, based on some experiments that I've done, the easiest way to get indexed on Google is to publish some press releases on domains with good authority score domain rank and have your you know pointing a link to your listing with the anchor text that you potentially also want to rank for using that specific canonical tag that you get from your Amazon listing. So the reason why this works better is because normally Google indexes across these websites. Like you know, if you publish through PR, news or something like that, they will be crawled, and so Google will find these links and then follow your Amazon listing, which obviously, as a consequence, would be indexed. Bradley Sutton: Okay, interesting. Now, taking it a step further, why should an Amazon seller even be concerned about indexing on Google like, um? Obviously, if you're running Google ads, you know your goal is to get direct sales from it. But just being ranked organically, um, what kind of bumps do you see on sales? Or how does it help a to be ranked high? I'm not just index. I mean index doesn't do much if you're ranked on page 30 or something, but how does ranking organically for a keyword? What's the potential there for helping sales? Leo: So there, are a few reasons why you want to be indexed on Google, and for the most, let's start from the most advanced ones, right? Advanced sellers they normally try to send traffic to Amazon, especially during the launch period, using external traffic, right? So Google, we know, is a good referral that tends to help your rankings, and so Amazon tends to reward you if they see traffic coming from Google. So if you're not indexed, you lose a chance to show Amazon that you are getting traffic from Google. Now, I have a theory that paid traffic has a little bit more weight than organic, but the reason why you want to be indexed and the reason why you might want to be indexed for certain keywords is so that when you drive traffic through the URL to Amazon, you can actually give attribution to that keyword. That's number one, right? So you can actually use these URLs as your two-step. Leo: Number two if you do a good job with your indexation and your listing is optimized, you actually also appear in the images, right? And so if people are looking for specific products, sometimes I search on Google using images because I'm looking for specific products that might be hard to find on Amazon, but if I look through the Google images and I find the product, then I go to Amazon, and so if you're not indexed, you're also not going to be able to be found there, and Google images actually gets a ton of traffic. So here are some of the reasons why, two of the reasons why. I can think of many more, but the most important are these ones. Google is still one of the largest search engine, and so missing out on that opportunity, I'm afraid it causes a lot of missed visibility for an Amazon seller at a listing level. Bradley Sutton: And then you've done some tests before where you noticed that if that Amazon can read what the search was from Google, so that when you get sales from a keyword in Google, it also potentially could help your Amazon ranking for that keyword, right? Leo: Yeah, that is correct. There was a test that we have done two years ago where everyone was talking about Google traffic and so we drove traffic straight from Google paid to Amazon without using any keyword in the URL, and then we noticed that for the keywords that we were actually bidding on, we saw a lift in ranking. I remember going from position I think it was 35 or so to position seven or five. So surprisingly we saw that Amazon was able to attribute that search query on Google and then the ranking as a result for the keyword was actually improving on Amazon as well. Bradley Sutton: Okay, interesting, interesting. Now let's switch and talk a little bit about images, because this also has to do with ranking on Amazon. It has to do with ranking on Google, getting indexed in Google. What has more of an impact with getting discovered or being able to be read by Google? Is it if you have an infographic and the actual words appear in the infographic, you know on the actual image, or is it the metadata, or it only works the best if you're doing both? Leo: In my opinion, you have to do both, and the reason is that right now, every search engine uses AI to detect subjects, text and everything on an image. You know, if you look, if you're a Facebook advertiser, you probably know that they've had this for a long time. If you add more text on an image than the image, the visual itself, your ad wouldn't have been approved, and so AI detection for images has been going on for a while. But now, since you know, ChatGPT came out and you know Lama from Facebook, we have, you know. We know we have a lot more information about this topic, and what we found is that the search engines, including Amazon and Google, they scan the content of your image and they're able to rank these images based on the content of that image, including subjects, context and in the subjects and text. Did I say that? Leo: So, basically, what Google cares the most on top of that is also the metadata, because the metadata helps the search engine classify that image. So, while the content itself helps them understanding okay, this is what this image is about the actual metadata is more technical for the crawlers, the engine themselves so that they can place you in certain categories. And so when it comes to Amazon, the content on the image right now, I noticed that through some different experiments, that is being used for ranking reasons. And so if you look at some products that don't have, for example, keywords on the images, they are less. You know there are multiple factors. Obviously, they play when it comes to rankings, but if you put two products side by side same ranking, same ratings, same being on market for the same time period, timeframe and same price one has text on images and keywords and one doesn't. Most likely the one with keywords on images is going to rank better. Bradley Sutton: Okay. So then what Amazon sellers should be doing is for their main images, or you know, the in their image carousel and their A+ content is I mean, obviously you can't have text in your main image. You know that's against terms of surface, although if you can have the packaging there, that's a good, that's a good opportunity. But then to get, hey, you use the right keywords, but then also, if you're using like photoshop or something you have and we're not going to go into detail, it's like there's a bunch of crazy stuff about copyright and there's fields there that he talks about in his presentation. You'll have to watch the Elite workshop for that. But you've been doing testing where it one has, it one doesn't, and then it gets you indexed on Google. You've actually seen where the ones who did it, their Amazon sales were like way higher than the ones who did it. Leo: Yeah, that is correct. We analyzed an e-brace on Amazon and this is, you know work that I was doing with a friend of mine, and we were trying to understand why these competitors were actually indexed on Google and they were indexed for certain keywords. Not the main keyword, but a variation of them. And so what I did I created this Google sheet where I was helping me understand which ones were indexed and for what keywords they were indexed and that led me to see that the ASINs that actually were indexed on Google were indexed for keywords that were present on the A+ banners. And so when we did that, what happened, this happened within 48 hours, we noticed that Google indexed that specific product image and they were actually featuring it as a search result on Google for the main search query, so that image wasn't used as a snippet or thumbnail for the listing itself. So the URL wasn't amazon.com/dp/ASIN, it was amazon.com/ the search you know embrace. Leo: So it took me to the search results page, but the image that they took as a featured image was actually the one of my client, and so that was very interesting because Google detected a refinement and it detected an update in that listing. It saw that that image was very relevant for the search query because of the way that we optimized it using metadata and then they used it as the main image on the Google search results. Now this, to me, is fascinating and is very important, because if you are a shopper and you're searching on Google for an e-brace and then you see this image, most likely that's psychological, most likely when you land on the Amazon search results page, you're going to go and find a product, you're going to go and click that product. So that added traffic, that added conversion rate, helped us recover the racing and the sales that we were losing. But that was a very interesting experiment that we did. Bradley Sutton: Interesting, okay. So again, if you guys want to get more information about that, that almost might be worth it just to subscribe to Helium 10 Elite for one week, just to get that presentation. So if you guys want to look into that, go to h10.me forward slash Elite and see it's only $99 extra, so make sure to sign up for that. Now, another thing that I think a lot of people have been talking about not just you, but you were one of the first ones to talk about semantic search and Cosmo and things like this, and we'll talk about what that means. But I think, just to set some groundwork, I think everybody understands that any search algorithm will evolve over time. That's the whole purpose. Like the companies who don't want to do well, they'll just keep their algorithm the same right. But anybody you know whether we're talking about Google, Facebook, TikTok has an amazing algorithm, Amazon. It changes over time and we've seen that. Bradley Sutton: You know, if we were searching five years ago on Amazon, it's different. And now if you've bought some how many of you who have bought something you search for a keyword that has to do with that and that thing that you bought is now at the top on your Amazon maybe not somebody else. That didn't happen like five, six years ago. Last year we showed an example of how you search a keyword that doesn't really exist. It's called noodle camera and no listing has the word noodle camera in it. But there was like maybe 30 listings that came up and it was like a stethoscope camera it looks like a noodle. So five years ago you put noodle camera it would say zero results because nobody has that in their listing and these listings don't have that keyword in there. But it's showing up because Amazon shows history that, oh, people don't know what this is called stethoscope camera but then they think it looks like a noodle. So now it's showing listing. So we've seen this even for a year. Now, first of all, Amazon science documents we've talked about it, but maybe 80%, 90%, never actually is 100% in production. Sometimes it goes into production, sometimes it doesn't. But what was it that made Cosmo so interesting these documents that talked about it, that you're like man. This is something that you think that Amazon is going to move towards. Leo: Yeah, the reason why, I think is something that would be applied at scale across the marketplace is because, as searchers, as buyers, as shoppers, our goal when we use a search engine is to find a product or information that we need in order to solve a problem. And so, as a technology company in this case we're talking about Amazon their goal is to improve, like Bradley said, the algorithm in order to simplify that search result and give you exactly what you're looking for, by burning some steps in the middle, right. And so that's what Cosmo is designed for. Cosmo is designed to be a man in the middle, between yourself and the search results, right, when you work together with it to give feedback back and forth. And so what they do right now they learn. You type a search query, they give you some result, you refine that result by clicking on some products that you think are relevant. And what they do with this information? They start building this knowledge graph, right. So a classic example if you go on Wikipedia and for something, Wikipedia normally links to other relevant sources. That's what they call the knowledge graph, right? They know that this is relevant to that right. And so what cosmo is trying to do, instead of you having to refine the search. They're refining it for you. Leo: So the example that I give in my presentation this morning is that, if someone is searching for winter coat, we saw a product that ranks number one on Amazon that doesn't have the word winter coat in the title. But yeah, they're ranked number one, and so this is shocking, right, like everyone's like oh come. Title is supposed to be the most important element on the page when it comes to optimization and some SEOs, but this time Amazon understood that you are looking for something that keeps you, to keep you warm, right. So now we're shifting from a keyword-based search to intent-based search, and so, as sellers, right now, what we need to do is understand what is the actual intent behind the person. What am I selling this to? I'm selling this to someone that wants to stay warm, right, that's what the purpose of a winter coat is, and so, with that intent in mind, we need to optimize listings so that we can convey the message through images, through the title, bullet points and description, so that Amazon, the new Cosmo, understands that this product is something that helps people stay warm. Leo: And what I think is going to happen also because of the shift in the way that these search results are built, which is more intent-based, is that Amazon then will start recommending also related products. So if you're looking for, if you type in winter coat, they say, okay, well, this person is trying to stay warm and so let me show them also some winter gloves and winter socks and maybe some winter boots, and that will change everything right. They will change the way we advertise, they will change the way we try to be associated with other products. They will change the way we also promote our listings. So that's very interesting and fascinating, but I think it's a good thing for the buyer, right, while for our sellers might be challenging to figure out again, how do we optimize our listings keeping this semantic concept in mind for the buyer? And they've already proven. If you look at the Amazon science document in the research papers, they're already saying that they're seeing a lift in conversion rate when Cosmo is applied to a search result page. So we must pay attention to these and monitor certain. It's challenging right now to understand where this is applied, but we need to monitor better the Amazon marketplace and then evolve and adapt as Cosmo gets released into more categories. Bradley Sutton: Not to be controversial here, but to me it's almost it's different, but it's not different. Like, at the end of the day, Amazon wants to make money, right, so that winter coat that became number one. It's not number one necessarily because of new algorithm, because it would not be number one unless that is one of the best converting ones, because that's what gives Amazon the best chance to make money. But I think where the difference here is, or what's something that's quote unquote new, is it gives people more at bats. Like maybe I never. Even if I didn't have winter coat in my title, it might've been almost impossible for me to get on page one. But now Amazon is all right, let's just throw it here. Oh, shoot, look at that, how well it's converting. Let's go ahead and push it all the way to the top, whereas maybe you know, four years ago, you know, unless you were super optimized for a certain keyword, you would never even have the ad back. Like you would never even be able to get on page one, you know, outside of PPC or something. So to me that's like the difference, but something also. Again, I keep saying I don't want to be controversial, but it's going to be because there's a lot of people I respect in the industry who have been talking a lot about things that and I agree mostly with them. But I completely disagree when they say things like, oh, tools like maybe Helium 10, if they don't change it's going to be out of date. To me, I cannot see a world where the traditional forms of keyword research, are going to be not as important In the future, if Amazon is super intuitive, of course that's going to evolve. Bradley Sutton: But the main reason we do keyword research is to get indexed and to also make our listing. Initially because the Amazon algorithm is based on buyer interaction, right. So once it's been out there for three, four weeks, they have so many data points and how people searched and what they clicked on and stuff that. Okay, now we can start doing advanced algorithms. But to even get it in the right pages you had to have done the regular keyword research to show Amazon. Because when you're brand new, day zero of your listing, Amazon has no idea what it is. It goes by the image, it goes by what you have in the title and how you have it. So my personal opinion is that no like. Of course, little things are going to change with keyword research here or there, but the main core of hey, let me find the most important keywords. That's not going to change because you have to tell Amazon on day one what is your product. Leo: So, Bradley, I agree with you and I think there is one important detail that is the link between what you're saying and what this all semantic stuff is about. Right, the reason why that winter coat might be ranking number one, even though the winter coat is not in the title is attributes of the winter coat. You know Amazon right now, which before they probably weren't doing before Cosmo, right, they're looking at the attributes. So most likely they are ranking this one very well because it contains, uh, goose feathers, or they have 300 grams of goose feathers per square meter or whatever foot, and so they now are using these attributes to understand is this product warmer than this one? So, while the keyword research tools are always going to be needed, what I think is an opportunity for companies like Helium 10 is now provide additional information to the seller together with the main keywords. That helps also the listing be more relevant for Cosmo, using attributes related to those keywords. So, if the keyword is winter coat, what are the main attributes of coats? Right? What does a coat have to have? Waterproof, has to be warm. What kind of feeling? Is it polyester? Is it goose feathers? Also, is it long or short? Things like that are going to be the difference between the traditional keyword research tools and the semantic powered keyword research tools. If you guys give the sellers the same list of keywords and, by the way, here are some attributes related to these keywords, that will help Amazon Cosmo understand more about your product. I think that's the winner, in my opinion. Bradley Sutton: Yeah, and in his presentation he talked a lot about different things you can do to be more semantically relevant and you know, using ChatGPT, so some really good features there. But that's important because you know, the it's not just, we're not just talking about Amazon SEO, it's also going to help you on Google and Bing and these, these other things and there's things that just the human mind we can't process, but a computer can process and tell you hey, this is, this is the keywords with the buyer intent and this is the most important, this is how you can relate yourself. So, regardless of how much of this Amazon develops, it's already important now for outside of Amazon indexing. Now, before we get into your last strategy, and I have just a couple of questions for you if people want to get more information, reach out to you, find out about your new project you're working on, or just reach out to you. How can they find you out there? Leo: I have my own website right now. It's leosgovio.com, so you can reach out to me on through my website. Bradley Sutton: And spell that, because it's not spelled exactly as you might think. Leo: It's l-e-o and then s as in Sam, g as in George, o, v as in Victor, i o. Yeah, over there I have some information also about the semantic SEO stuff. So if you're more interested about this, I'd be happy to share my knowledge in depth, and LinkedIn is one of the platforms that I use the most. Bradley Sutton: Excellent. All right Favorite Helium 10 tool? Leo: Magnet Bradley Sutton: If you were a head of product at Helium 10, what is one tool or function that you would bring that we do not have currently? Leo: I believe I will combine what we just discussed about into one tool, and so it's an hybrid between a listing analyzer powered with recommendation based on the semantic stuff. Bradley Sutton: And your 30 to 60 second tip can be about anything for sellers out there. Leo: Leverage. Try to think about your current strategy when it comes to product inserts. To leverage it for UGC. Bradley Sutton: All right guys. If you want more information, go to leosgovia.com. Check them out in the Helium 10 Elite, the Q2 workshop replay. But thank you, guys, so much for joining us and we'll definitely be reaching out to Leo next year to see what he's been up to. Leo: Thanks, Bradley, I appreciate you having me again and, yeah, looking forward to the next one. Bradley Sutton: Adios desde España.
Spliced by Brothers-In-Crime 01. Depeche Mode - Never Let Me Down Again 02. Yazoo - Only You 03. Erasure - Sometimes 04. Yazoo - State Farm 05. Pet Shop Boys - Domino Dancing 06. Pet Shop Boys - West End Girls 07. Erasure - It Doesn't Have To Be 08. Depeche Mode - Enjoy The Silence 09. Depeche Mode - Policy Of Truth 10. Kraftwerk - The Robot 11. New Order - True Faith 12. New Order - Bizarre Love Triangle 13. Pet Shop Boys - What Have I Done To Deserve This 14. Depeche Mode - Strangelove 15. Erasure - Stop! 16. Erasure - Chains Of Love 17. Human League - Don't You Want Me 18. Erasure - Oh L'Armour 19. Pet Shop Boys - In The Night 20. Pet Shop Boys - Opportunities 21. Depeche Mode - World In My Eyes 22. Kraftwerk - The Model 23. Erasure - Victim Of Love 24. Erasure - Heavenly Love 25. Pet Shop Boys - Always On My Mind 26. Depeche Mode - Behind The Wheel 27. Pet Shop Boys - Suburbia 28. Yazoo - Don't Go 29. Depeche Mode - Just Can't Get Enough 30. Depeche Mode - Master & Servant 31. Visage - Fade To Grey 32. Erasure - Blue Savannah 33. Yazoo - Situation 34. New Order - Blue Monday 35. Kraftwerk - Tour De France 36. Yello - Oh Yeah 37. Depeche Mode - A Question Of Time 38. Erasure - Make Me Smile 39. OMD - Enola Gay MORE RETRO MIXTAPES ▶️ bit.ly/RA_Retro reactivateasia.com FIND US ON OUR SOCIALS! FACEBOOK
(Spliced from Sunday night's LIVE!) Ryan Lowe returns to Home Park for the first time since his departure for Preston North End a week after beating Steven Schumacher's Stoke City! #pafc | #pnefc Hosted on Acast. See acast.com/privacy for more information.
(Spliced from Wednesday Night's LIVE) Joe, Sam and Jon join Aaron and discuss Saturday's trip to Ewood Park as Plymouth Argyle face John Eustace's Blackburn Rovers in a game neither side can ill afford to lose as the EFL Championship season draws closer to the end. #pafc | #rovers Hosted on Acast. See acast.com/privacy for more information.
CanaryCryRadio.com Canary Cry Radio #162 - 09.25.2023 Christians Who Attend Burning Man - 2023 Church Intelligence Report Basil's Voyage Through the World's Premiere Transformative Event! The Show Operates on the Value 4 Value Model: http://CanaryCry.Support Join the Supply Drop: http://CanaryCrySupplyDrop.com Submit Articles to NewsTalk: http://CanaryCry.Report Join the T-Shirt Council: http://CanaryCryTShirtCouncil.com Resource: Index of MSM Ownership (Harvard.edu) Resource: Aliens Demons Doc (feat. Dr. Heiser, Unseen Realm) Tree of Links: http://CanaryCry.Party RECKONING! From Basil's muddy boots of Burning Man to your ears! This is how the bleeding edge of Christian apologetics looks like in the 21st century! Last year in 2022, Last year in 2022, Basil experienced podcast tragedy at Burning Man when he lost all the SD cards containing vital interviews and conversations he captured from the annual transformative event held in the Black Rock Desert. A discouraged Basil didn't have any plans to attend this year's Burning Man, until news starting coming out that tickets were being sold for 1/10th of the normal cost. Seeing it as a sign from God, Basil packed up and headed out to Black Rock Desert once again! Of course, the 2023 Burning Man event was a Mainstream Media and Alternative Media playground, as bad weather reports began to trickle out of the desert. Both sides of the media decided to tailor the news to their own messaging: Mainstream Media pushed the Climate Change angle on why Burning Man flooded out, while Alternative Media not only pushed untruths about the situation on the dirt (like Ebola breakout), but did so with religious fervor and judgment justified by false information. Both were guilty of sensationalism. On this episode, we do not leave any room for speculation! We get a mere 5 hour report documenting informed and grounded Christians spending time in the midst of the “hive mind” gathering information for the church, but also sharing the truth that sets us free, the Gospel of Jesus Christ, when opportunities are presented. These are actual boots-on-the-ground reporting from the catalyst of culture! hear live sounds from inside the Burning Man Temple, at the Man burn itself, and the voices of random people attenting the event. We structured the episode around a post-burn conversation between Basil, Carl Teichrib and Bob Worley. Spliced in are raw audio sound from inside the Burning Man Temple, at the Man burn itself, and the voices of random people living amogst the dirt at Burning Man 2023. If you ever wondered what it means to make disciples of all nations and to fulfill the Great Commission, you need to listen to this episode! Share it with all of your friends and family who may get triggered when they hear that this is an episode of Jesus followers attending Burning Man! We do our best to live up to our tagline, “Think Outside The Cage!” CHAPTER TIMESTAMPS 00:00:00 - Introductions & E.P : Sir Jacob Hi-Line Hoss and Knight of the Issachar Pursuit 00:16:11 - Chapter 1: Basil Searching for Carl and the Camp of the Unknown God 00:45:41 - Chapter 2: Convo with Carl and Bob 01:20:57 - Chapter 3: The Research…and “sparkle ponies” 01:30:06 - Chapter 4: The Survey 02:05:28 - Chapter 5: Anamalia 02:14:04 - Chapter 6: The Chapel of Babel 02:35:50 - Chapter 7: Pharmakeia 02:43:20 - Chapter 8: The Temple Burn 03:18:27 - Chapter 9: The Man Burn, Raw Audio 03:23:25 - Chapter 10: The Media Psyop 03:48:04 - Chapter 11: Bob the Burn Evangelist 04:31:31 - Chapter 12: How to Share the Gospel at Burning Man 04:40:07 - Chapter 13: Closing Thoughts 04:46:38 - Canary Cry Playlist Canary Cry Playlist: LittleOwen - Don't Give Up Psalm40 - Revelation5 Marty B - Glorify James M - Canary Cry Awaits (Fly Away) Past Episodes CCR 144: Metamorphosis – Burning Man 2019 (September 10, 2019) CCR 137: Truthstream for the Mind w/ Melissa Dykes (November 30, 2018) CCR 134: After Burning Man w/ Carl Teichrib (September 29, 2018) CCR 132: Camp of the Unknown God (August 8, 2018) FLYBY: Burning Man '18 – Boots on the Ground! (September 27, 2018) CCR 078: Transformative Events with Carl Teichrib (November 1, 2014) Additional Reports on Patreon CCConvo 008: Basil's Burn Report! CCConvo 009: Basil's Burn Audio Tour! - 09.26.2019
CanaryCryRadio.comCanary Cry Radio #162 – 09.25.2023Christians Who Attend Burning Man – 2023 Church Intelligence ReportBasil's Voyage Through the World's Premiere Transformative Event!The Show Operates on the Value 4 Value Model: http://CanaryCry.Support Join the Supply Drop: http://CanaryCrySupplyDrop.com Submit Articles to NewsTalk: http://CanaryCry.Report Join the T-Shirt Council: http://CanaryCryTShirtCouncil.comResource: Index of MSM Ownership (Harvard.edu) Resource: Aliens Demons Doc (feat. Dr. Heiser, Unseen Realm)Tree of Links: http://CanaryCry.Party RECKONING! From Basil's muddy boots of Burning Man to your ears! This is how the bleeding edge of Christian apologetics looks like in the 21st century! Last year in 2022, Basil experienced podcast tragedy at Burning Man when he lost all the SD cards containing vital interviews and conversations he captured from the annual transformative event held in the Black Rock Desert. A discouraged Basil didn't have any plans to attend this year's Burning Man, until news starting coming out that tickets were being sold for 1/10th of the normal cost. Seeing it as a sign from God, Basil packed up and headed out to Black Rock Desert once again! Of course, the 2023 Burning Man event was a Mainstream Media and Alternative Media playground, as bad weather reports began to trickle out of the desert. Both sides of the media decided to tailor the news to their own messaging: Mainstream Media pushed the Climate Change angle on why Burning Man flooded out, while Alternative Media not only pushed untruths about the situation on the dirt (like Ebola breakout), but did so with fervor and judgment justified by false information. Both were guilty of sensationalism. On this episode, we do not leave any room for speculation! We get a mere 5 hour report documenting informed and grounded Christians spending time in the midst of the “hive mind” gathering information for the church, but also sharing the truth that sets us free, the Gospel of Jesus Christ, when opportunities are presented. These are actual boots-on-the-ground reporting from the catalyst of culture! We structured the episode around a post-burn conversation between Basil, researcher and author Carl Teichrib, and Bob Worley from the Camp of the Unknown God. Spliced in are raw audio sound from inside the Burning Man Temple, at the Man burn itself, and the voices of random people living amongst the dirt at Burning Man 2023.If you ever wondered what it means to make disciples of all nations and to fulfill the Great Commission, you need to listen to this episode! Share it with all of your friends and family who may get triggered when they hear that this is an episode of Jesus followers attending Burning Man! We do our best to live up to our tagline, “Think Outside The Cage!”CHAPTER TIMESTAMPS00:00:00 – Introductions & E.P : Sir Jacob Hi-Line Hoss and Knight of the Issachar Pursuit00:16:11 – Chapter 1: Basil Searching for Carl and the Camp of the Unknown God00:45:41 – Chapter 2: Convo with Carl and Bob01:20:57 – Chapter 3: The Research…and “sparkle ponies”01:30:06 – Chapter 4: The Survey02:05:28 – Chapter 5: Anamalia 02:14:04 – Chapter 6: The Chapel of Babel02:35:50 – Chapter 7: Pharmakeia 02:43:20 – Chapter 8: The Temple Burn 03:18:27 – Chapter 9: The Man Burn, Raw Audio03:23:25 – Chapter 10: The Media Psyop03:48:04 – Chapter 11: Bob the Burn Evangelist04:31:31 – Chapter 12: How to Share the Gospel at Burning Man04:40:07 – Chapter 13: Closing Thoughts04:46:38 – Canary Cry PlaylistCanary Cry Playlist:LittleOwen – Don't Give UpPsalm40 – Revelation5Marty B – GlorifyJames M – Canary Cry Awaits (Fly Away)Past Burning Man Episodes:CCR 144: Metamorphosis – Burning Man 2019 (September 10, 2019)CCR 137: Truthstream for the Mind w/ Melissa Dykes (November 30, 2018)CCR 134: After Burning Man w/ Carl Teichrib (September 29, 2018)CCR 132: Camp of the Unknown God (August 8, 2018)FLYBY: Burning Man '18 – Boots on the Ground! (September 27, 2018)CCR 078: Transformative Events with Carl Teichrib (November 1, 2014)Additional Reports on PatreonCCConvo 008: Basil's Burn Report!CCConvo 009: Basil's Burn Audio Tour! – 09.26.2019
Its time for Acoustic pleasure and this month once again we welcome those LA funkers 2 Reels. The lads have provided us with another quality mix with some exclusive edits for your musical enjoyment. Watch out for their brand new single Spliced coming soon with some really hot remixes. In the first hour your show host lays down some top tracks as always, another fantastic 2 hours of tunes for your musical enjoyment
A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, “Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?” A vast majority of breast cancers (~70%) are estrogen receptor-alpha positive (ER+), for which endocrine therapy is the common treatment. However, recurrence often occurs leading to tumor progression, metastasis and eventually patient death, and the underlying molecular mechanisms remain poorly understood. In this new editorial, researchers Chia-Chia Liu and Xiao-Song Wang from the University of Pittsburgh discuss their recent study regarding recurrent gene fusions — hallmarks of some cancers that resulted either from chromosomal rearrangements or from cis- or trans-splicing. “Importantly, selected oncogenic fusions have been matched with effective targeted therapy in several solid tumors. For instance, EML4-ALK, one of the most important oncogenic driver genes of non-small cell lung cancer (NSCLC) uncovered in recent years.” In addition to gene fusions resulting from genomic rearrangements, a read-through SLC45A3-ELK4 fusion transcript has been identified in prostate cancer which is associated with disease progression and metastasis. Although the whole genome and RNA sequencing provide an effective way to detect fusion genes, the downstream identification and validation of fusion genes or their products in solid tumors remains a major challenge. Through analysis of RNA-seq data from TCGA, the authors of this editorial and their co-authors recently identified a neoplastic fusion transcript RAD51AP1-DYRK4 in luminal B breast cancer (~17.5%) showing higher ki67 expression which is an indication of aggressive clinical characteristics. “In this study, we examined the utility of MEK inhibitor trametinib (Mekinist) currently used for treating melanoma with BRAF mutations, in blocking the MEK-ERK signaling driven by RAD51AP1-DYRK4 fusion. Interestingly [...] RAD51AP1-DYRK4 may endow sensitivity to MEK inhibition in luminal B breast cancer [13]. To our knowledge, this is one of the few non-traditional fusions generated by read-through events in the absence of DNA rearrangement that play an important role in tumorigenesis.” DOI - https://doi.org/10.18632/oncotarget.28438 Correspondence to - Xiao-Song Wang - xiaosongw@pitt.edu Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28438 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, luminal B breast cancer, RAD51AP1-DYRK4, MEK inhibitor, chimerical transcript About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ Twitter - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Media Contact MEDIA@IMPACTJOURNALS.COM 18009220957
Do you know the answers to these 80's questions? I bet you can't! In this week's episode, we take a slice of the live stream from this past week and talk with Tony D., about all things 80's. I do a little trivia game with Rick and Tony and as always, find ourselves laughing, giggling, and just enjoying a good 'ole time hanging out. As always, thank you for stopping by. Please visit our website: All About The Joy and add, like and share. I'd appreciate that greatly. Also, if you want to find me anywhere on social media, please check out the link in bio page. Music By Geovane Bruno, Moments, 3481Editing by Team A-JHost, Carmen Lezeth
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.27.525873v1?rss=1 Authors: Poth, V., Do, H. T. T., Foerderer, K., Tschernig, T., Alansary, D., Helms, V., Niemeyer, B. A. Abstract: Balanced Ca2+ homeostasis is essential for cellular functions. STIM2 mediated Store-Operated Ca2+ Entry (SOCE) regulates cytosolic and ER Ca2+ concentrations, stabilizes dendritic spine formation and drives presynaptic spontaneous transmission and ER stress in neurons. Recently identified alternative spliced variants expand the STIM protein repertoire, uncover unique functions and facilitate our understanding of tissue specific regulation of SOCE. Here, we describe an addition to this repertoire, a unique short STIM2 variant (STIM2.3/STIM2G) present only in old world monkeys and humans with expression in humans starting with the beginning of brainwave activity and upon synapse formation within the cerebral cortex. In contrast to the short STIM1B variant, STIM2.3/STIM2G increases SOCE upon stimulation independently of specific spliced in residues. Basal cluster formation is reduced and analyses of several additional deletion and point mutations delineate the role of functional motifs for Ca2+ entry, NFAT activation and changes in neuronal gene expression. In addition, STIM2.3/STIM2G shows reduced binding and activation of the energy sensor AMPK. In the context of reduced STIM2.3 splicing seen in postmortem brains of patients with Huntingtons disease, our data suggests that STIM2.3/STIM2G is an important regulator of neuronal Ca2+ homeostasis, potentially involved in synapse formation/maintenance and evolutionary expansion of brain complexity. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Piaf at the Gate review - A Christmas Carol - First fortnight, Spliced
This week, Jacob picks 1992's Glengarry Glen Ross. This movie has a star-studded cast including, Al Pacino, Jack Lemmon, Alec Baldwin, Alan Arkin, Ed Harris, Kevin Spacey, and Jonathan Pryce. We get into a tangent about Mamma Mia!, marketing, sales, and Cutco. Spliced between these tangents, we do actually talk about the movie; including the performances, the awesome writing, and much more! This movie was directed by James Foley. GD4AM: 83/100 IMDb: 7.7/10 Metacritic: 82/100 RT: 95% An examination of the machinations behind the scenes at a real estate office. This movie is currently streaming on Hulu. NEXT MOVIE REVIEW: North by Northwest - currently streaming on HBOMAX.
We all knew Bethany and I couldn't go that long without recording something, so after finishing A Court of Silver Flames for our book club, we knew we had to record more of our thoughts! Thus, the ACOTAR bonus episode was born! Spliced up with some previously removed tangents with took in season 3, what we planned to be a short episode turned into an hour and a half of ACOTAR goodness!Enjoy! And we'll be back in a few weeks with the start of season 4.
On this weeks episode we dive into the new releases from No Pressure, Dagger Threat and of course the new singles from Turnover This weeks bands include: Borders, Darko (US), Counterparts, Death Grip, Turnover, Mire Lore, No Pressure, Dagger Threat, orphantwin, The Oklahoma Kid, Bleed From Within, thoughtcrimes, Bury Tomorrow, Spliced, Of Virtue, In Somni, Moments and Antagonist A.D.
On this week's episode, Chris and Sylvie mock God's design with animalistic abominations and unbridled gross-out humour with Nelvana's Spliced. While speculating on what the evil doctor's plan was for all his animal hybrids on his abandoned island, we chat about the show's animation style and classic inspirations and the long lost comedic art of "RAAAAANNNNNDOOOOOM" style jokes. Plus, Sylvie has some choice words for the recent Station Eleven adaptation and both wonder what kind of animal hybrid they would choose to be. Episode covered is Episode 6 "Honorary Freak" / "Come to the Dork Side." If you liked what you heard please consider giving us a like, share, follow, and rating on your podcatcher of choice to help us grow and reach a wider audience. Follow us on Twitter at https://twitter.com/CartoonNightPod?s=20 Theme song by https://soundcloud.com/hvsyn
You may think pairing Splice (2009) with The Wisher (2002) makes no sense, but here's a fun fact: The Wisher is also widely known as Spliced!
THIIIRD Waves is the sonic sibling of THIIIRD magazine. Bringing a bi-monthly mix of sound and thought to Soho Radio, it features topical discussions and interviews around a central theme exploring arts, activism, culture, entertainment, and community. Spliced with an eclectic mix of music influenced by cultural diasporas throughout and finished by a DJ set.Cancel culture is an ever provocative term and hot topic. There is a lot of fear surrounding 'being canceled' but who are the odds really stacked against? On this episode, we explore how we hold people and organisations accountable, and separate the art from the artist.This show was produced by Daniela Hornskov Sun.This is the Soho Radio podcast, showcasing some of the best broadcasts from our online radio station, right from the heart Soho London.Across our Music and Culture channels, we have a wide range of shows covering every genre, along with chat shows, discussions and special broadcasts.To catch up on all Soho Radio shows from both our music and culture channels head on over mixcloud.com/sohoradio or tune in live anytime at sohoradiolondon.com.This is a Soho Radio Productions Podcast.Support this show http://supporter.acast.com/soho-radio. See acast.com/privacy for privacy and opt-out information.
This week we talked about a new horror movie on Shudder called Slaxx and a new horror anthology from Image Comics, The Silver Coin, the first issue by Chip Zdarsky and Michael Walsh out now! We hit Mortal Kombat and close out our thoughts on The Falcon and the Winter Soldier series.
THIIIRD Waves is the sonic sibling of THIIIRD magazine. Bringing a bi-monthly mix of sound and thought to Soho Radio, it features topical discussions and interviews around a central theme exploring arts, activism, culture, entertainment and community. Spliced with an eclectic mix of music influenced by cultural diasporas throughout and finished by a DJ set.The arts industry is one of those sectors that rely on human interaction, whether it is to experience a live theatre performance, music in a venue or at a festival or even just popping into a gallery. So what happens when all those spaces disappear or at best become socially distanced.Max Golfar works for Hootananny the venue in Brixton as Music & Events Manager, he is a working DJ under the alias of Fizzy Gillespie and runs the event brand and label, Swing & Bass.This show was produced by Daniela Hornskov Sun.This is the Soho Radio podcast, showcasing some of the best broadcasts from our online radio station, right from the heart Soho London.Across our Music and Culture channels, we have a wide range of shows covering every genre, along with chat shows, discussions and special broadcasts.To catch up on all Soho Radio shows from both our music and culture channels head on over mixcloud.com/sohoradio or tune in live anytime at sohoradiolondon.com.This is a Soho Radio Productions Podcast.Support this show http://supporter.acast.com/soho-radio. See acast.com/privacy for privacy and opt-out information.
THIIIRD Waves is the sonic sibling of THIIIRD magazine. Bringing a bi-monthly mix of sound and thought to Soho Radio, it features topical discussions and interviews around a central theme exploring arts, activism, culture, entertainment and community. Spliced with an eclectic mix of music influenced by cultural diasporas throughout and finished by a DJ set.The arts industry is one of those sectors that rely on human interaction, whether it is to experience a live theatre performance, music in a venue or at a festival or even just popping into a gallery. So what happens when all those spaces disappear or at best become socially distanced.Max Golfar works for Hootananny the venue in Brixton as Music & Events Manager, he is a working DJ under the alias of Fizzy Gillespie and runs the event brand and label, Swing & Bass.This show was produced by Daniela Hornskov Sun.This is the Soho Radio podcast, showcasing some of the best broadcasts from our online radio station, right from the heart Soho London.Across our Music and Culture channels, we have a wide range of shows covering every genre, along with chat shows, discussions and special broadcasts.To catch up on all Soho Radio shows from both our music and culture channels head on over mixcloud.com/sohoradio or tune in live anytime at sohoradiolondon.com.This is a Soho Radio Productions Podcast.Support this show http://supporter.acast.com/soho-radio. See acast.com/privacy for privacy and opt-out information.
THIIIRD Waves is the sonic sibling of THIIIRD magazine. Bringing a bi-monthly mix of sound and thought to Soho Radio, it features topical discussions and interviews around a central theme exploring arts, activism, culture, entertainment and community. Spliced with an eclectic mix of music influenced by cultural diasporas throughout and finished by a DJ set.This is the Soho Radio podcast, showcasing some of the best broadcasts from our online radio station, right from the heart Soho London.Across our Music and Culture channels, we have a wide range of shows covering every genre, along with chat shows, discussions and special broadcasts.To catch up on all Soho Radio shows from both our music and culture channels head on over mixcloud.com/sohoradio or tune in live anytime at sohoradiolondon.com.This is a Soho Radio Productions Podcast.Support this show http://supporter.acast.com/soho-radio. See acast.com/privacy for privacy and opt-out information.
THIIIRD Waves is the sonic sibling of THIIIRD magazine. Bringing a bi-monthly mix of sound and thought to Soho Radio, it features topical discussions and interviews around a central theme exploring arts, activism, culture, entertainment and community. Spliced with an eclectic mix of music influenced by cultural diasporas throughout and finished by a DJ set.This is the Soho Radio podcast, showcasing some of the best broadcasts from our online radio station, right from the heart Soho London.Across our Music and Culture channels, we have a wide range of shows covering every genre, along with chat shows, discussions and special broadcasts.To catch up on all Soho Radio shows from both our music and culture channels head on over mixcloud.com/sohoradio or tune in live anytime at sohoradiolondon.com.This is a Soho Radio Productions Podcast.Support this show http://supporter.acast.com/soho-radio. See acast.com/privacy for privacy and opt-out information.
Jon McGoran discusses point of view, the pros and cons of first-, second-, and third-person point of view, and reader expectations based on considerations such as genre. He discusses the importance of narrative economy and triangulation--how one character's observations of another character can give the reader a lot of information about both the observed character and the observer. And he shares a formatting tip for helping to keep track of POV characters, and to see where POV shift occur throughout your manuscript. Jon McGoran is the author of ten novels for adults and young adults, including the award-winning YA science fiction thrillers SPLICED, SPLINTERED and SPIKED, and the acclaimed thrillers DRIFT, DEADOUT, and DUST UP. He cohosts THE LIARS CLUB ODDCAST, a podcast about writing and creativity. He is a freelance writer, developmental editor, and writing coach.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.10.376871v1?rss=1 Authors: Wilks, C., Schatz, M. C. Abstract: Abstract Motivation: Long read sequencing has increased the accuracy and completeness of assemblies of various organisms' genomes in recent months. Similarly, spliced alignments of long read RNA sequencing hold the promise of delivering much longer transcripts of existing and novel isoforms in known genes without the need for error-prone transcript assemblies from short reads. However, low coverage and high-error rates potentially hamper the widespread adoption of long-read spliced alignments in annotation updates and isoform-level expression quantifications. Results: Addressing these issues, we first develop a simulation of error modes for both Oxford Nanopore and PacBio CCS spliced-alignments. Based on this we train a Random Forest classifier to assign new long-read alignments to one of two error categories, a novel category, or label them as non-error. We use this classifier to label reads from the spliced-alignments of the popular aligner minimap2, run on three long read sequencing datasets, including NA12878 from Oxford Nanopore and PacBio CCS, as well as a PacBio SKBR3 cancer cell line. Finally, we compare the intron chains of the three long read alignments against individual splice sites, short read assemblies, and the output from the FLAIR pipeline on the same samples. Our results demonstrate a substantial lack of precision in determining exact splice sites for long reads during alignment on both platforms while showing some benefit from postprocessing. This work motivates the need for both better aligners and additional post-alignment processing to adjust incorrectly called putative splice-sites and clarify novel transcripts support. Availability and implementation Source code for the random forest implemented in python is available at https://github.com/schatzlab/LongTron under the MIT license. The modified version of GffCompare used to construct Table 3 and related is here: https://github.com/ChristopherWilks/gffcompare/releases/tag/0.11.2LT Copy rights belong to original authors. Visit the link for more info
THIIIRD Waves is the sonic sibling of THIIIRD magazine. Bringing a bi-monthly mix of sound and thought to Soho Radio, it features topical discussions and interviews around a central theme exploring arts, activism, culture, entertainment and community. Spliced with an eclectic mix of music influenced by cultural diasporas throughout and finished by a DJ set.This is the Soho Radio podcast, showcasing some of the best broadcasts form our online radio station, right from the heart Soho London.Across our Music and Culture channels, we have a wide range of shows covering every genre, along with chat shows, discussions and special broadcasts.To catch up on all Soho Radio shows from both our music and culture channels head on over mixcloud.com/sohoradio or tune in live anytime at sohoradiolondon.com.This is a Soho Radio Productions Podcast.Support this show http://supporter.acast.com/soho-radio. See acast.com/privacy for privacy and opt-out information.
THIIIRD Waves is the sonic sibling of THIIIRD magazine. Bringing a bi-monthly mix of sound and thought to Soho Radio, it features topical discussions and interviews around a central theme exploring arts, activism, culture, entertainment and community. Spliced with an eclectic mix of music influenced by cultural diasporas throughout and finished by a DJ set.This is the Soho Radio podcast, showcasing some of the best broadcasts form our online radio station, right from the heart Soho London.Across our Music and Culture channels, we have a wide range of shows covering every genre, along with chat shows, discussions and special broadcasts.To catch up on all Soho Radio shows from both our music and culture channels head on over mixcloud.com/sohoradio or tune in live anytime at sohoradiolondon.com.This is a Soho Radio Productions Podcast.Support this show http://supporter.acast.com/soho-radio. See acast.com/privacy for privacy and opt-out information.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.02.279208v1?rss=1 Authors: Sahlin, K., Makinen, V. Abstract: Long-read RNA sequencing techniques are quickly establishing themselves as the primary sequencing technique to study the transcriptome landscape. Many such analyses are dependent upon splice alignment of reads to the genome. However, the error rate and sequencing length of long-read technologies create new challenges for accurately aligning these reads. We present an alignment method uLTRA that, on simulated and synthetic data, shows higher accuracy over state-of-the-art with substantially higher accuracy for small exons. We show several examples on biological data where uLTRA aligns to known and novel isoforms with exon structures that are not detected with other aligners. uLTRA is available at https://github.com/ksahlin/ultra. Copy rights belong to original authors. Visit the link for more info
This week I chat with actor Timmy Creed who has a one man show called Spliced that examines his relationship with our national game of hurling, showcases some of the wonders of the game, and confronts some difficult questions about the culture with GAA and team sports.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.23.234237v1?rss=1 Authors: Csaba, G., Berchtold, E., Hadziahmetovic, A., Gruber, M., Ammar, C., Zimmer, R. Abstract: While absolute quantification is challenging in high-throughput measurements, changes of features between conditions can often be determined with high precision. Therefore, analysis of fold changes is the standard method, but often, a doubly differential analysis of "changes of changes" is required. Differential alternative splicing is an example of a doubly differential analysis, i.e. fold changes between conditions for different isoforms of a gene. EmpiRe is a quantitative approach for various kinds of omics data based on fold changes for appropriate features of biological objects. Empirical error distributions for these fold changes are estimated from Replicate measurements and used to quantify feature fold changes and their directions. We assess the performance of EmpiRe to detect differentially expressed genes applied to RNA-Seq using simulated data. It achieved higher precision than established tools at nearly the same recall level. Furthermore, we assess the detection of alternatively Spliced genes via changes of isoform fold changes (EmpiReS) on distribution-free simulations and experimentally validated splicing events. EmpiReS achieves the best precision-recall values for simulations based on different biological datasets. We propose EmpiRe(S) as a general, quantitative and fast approach with high reliability and an excellent trade-off between sensitivity and precision in (doubly) differential analyses. Copy rights belong to original authors. Visit the link for more info
Rik Scott is the man behind the cool but anonymous voice heard on many of the UK's hottest radio stations. But behind that super-hip sound is a guy who has fallen apart on air and off. Elinor Hamilton talks to him about his mental health, multiple marriages and more. Recorded in May 2020. Produced by Karl Svenson at Tadah Media.
In this episode Matt Crawford speaks with author Daphne Geismar about her family's account of hiding during WWII in the Netherlands. This is a beautiful and heart wrenching book that should be read by all. Geismar gathered her family members personal diaries written before, during and after Nazi occupation. Spliced together to show how each relative experienced these horrible events differently this is a rich narrative that touches you deeply. Copies of handwritten diary pages, artifacts and drawings add even more intimacy and paint to this account. Please read this book.
Spliced audio taken from 8.13.20 Zoom call with business mentor and friend Suzanne VanOver. Conversations about what we have learned about CBD, why we choose the Young Living Brand of CBD and important information about how it is grown and developed. --- Send in a voice message: https://podcasters.spotify.com/pod/show/melissa-weeden/message
Long lines. Grumpy shoppers. Rude cashiers. Can we just stay home and get ready for Christmas from the comfort of our couches? Sure. But Christmas shopping can also give us opportunities, too, if we take them. Take 5 min to join me and let's talk about the joy we can spread in our shopping quests. Music: "Carol of the Bells" by Lady Jazzer Tribe of Music CC 3.0 by Share-alike, Spliced and de-amplified
Brought to you by @ThisIsCork - Recorded in The Long Valley, an interview with Timmy Creed, who wrote and performs 'Spliced' an autobiographical theatrical piece about his complex relationship with Hurling & The GAA; he loves it, he hates it, he learns it, he leaves, he comes back... www.spliced.ie for more information... Podcast produced and presented by Ronan Leonard @ronanfromcork
Locked On Bruins - Daily Podcast On UCLA Bruins Football & Basketball
Coming off the euphoria of Saturday's win over Arizona State, Bryan Fenley serves up the latest happenings on the Bruins Football Practice Field from Monday. Plus, Fenley jibber jabbers about the basketball team and brings you the most poignant things to come out of the team's Monday media availability session. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Locked On Bruins - Daily Podcast On UCLA Bruins Football & Basketball
Coming off the euphoria of Saturday's win over Arizona State, Bryan Fenley serves up the latest happenings on the Bruins Football Practice Field from Monday. Plus, Fenley jibber jabbers about the basketball team and brings you the most poignant things to come out of the team's Monday media availability session. Learn more about your ad choices. Visit megaphone.fm/adchoices
Episode 45 - The Perfect Orgy In this episode, Jay & Kay are joined by their friends Nate, Liv, Amy & Rory with guest audio appearances by Donny and Marie as they try to describe the sexy details of a 10 person orgy, which, as you can imagine, can be very difficult to recall because there are so many individual sexy experiences occurring simultaneously. The night evolved from what was supposed to be a private dinner between Donny & Marie and Jay & Kay but grew to include Nate & Liv, Amy & Rory as well as a very sexy single female named Sonja and our now well known artist friend Ryan. There is a lot of shared laughter in this episode and we work to try to minimize or explain inside jokes. If you are a veteran listener then you will know these important people in our lives and laugh along with us. If you're a new listener, you will be treated to what lifestyle friendships can and do become, tightly interwoven circles of trust and support. Technical note: About 45 seconds in to our cabin recording the input wire becomes partially removed creating a less powerful sound. This resolves after a few minutes. Spliced into our conversation are recordings from Donny and Marie, our guests from the Pacific Northwest who came to Washington DC for a vacation of our Nation's Capital. They wanted to see the Cherry Blossom Festival and tour the Smithsonian museums, but no vacation is complete without a 10-person orgy. They graciously share their memories with us, essentially making this two podcasts in one. As fun as the friendships are and as sexy as the orgy was, there are many great personal details sprinkled throughout. Introspective reflections and thoughtful musings permeate this episode. Those details, shared in the context of our move away from these friends, make Episode 45 my personal favorite and I hope you enjoy it as much as we enjoyed making it. -J & K Mentioned: Temptation and Desire with the @PLAYGRND crew- Feb 2020 - info@playgrnd.events Dr. and Sexy Thing Line 1/Line 2 Oregon TMS
We’re back with a jam-packed episode of theatre, art and movies. Kicking off with the latest Harry Potter, Wizarding world tale of The Crimes of Grindelwald, we then move to talk Pre-Raphaelites at the Tate Britain, Hadestown at The National Theatre and a few Widows and Freddie Mercury to finish. Spliced between them all, we […]
Don takes calls on small cap investing, portfolios, credit scores and more. Spliced in between these we hear why stocks are still the best place to put your money, the arguments against commodities as investment, and why money and happiness are not actually as disconnected as has often been said. Small cap value investing and why it’s so lucrative. Weighing DFA and Vanguard portfolios. Stocks versus commodities? Are you serious? Why money actually is strongly linked to happiness after all. Why diversified stocks always win out over trying to beat the market. Stock picking and underperformance as a chronically linked combination. Investing should never be speculative, it is not gambling. What’s the best way to pay off your credit card. 401411 — http://www.401411.com/ Vestory — http://vestory.com/ Vanguard —https://about.vanguard.com/ Paul Merriman — https://paulmerriman.com/ SEC — https://www.sec.gov/ DFA — https://us.dimensional.com/ Tesla — https://www.tesla.com/ Wall Street Journal — https://www.wsj.com MarketWatch — https://www.marketwatch.com/ Michael Oliver Article — https://www.marketwatch.com/story/the-stock-market-is-the-stupidest-asset-out-there-but-this-asset-is-hot-hot-2018-03-22
Perfection in minor key. Calling out to me. Forgotten realms of childhood memories. Terror in the night. Tossing and turning melodies. Given over to the fear. Suicide contemplation. Lost the war. Inside only nightmares remain. Devil inside. Taking blades along my spine. Spliced together, fading memories, of who I used to be.
For the hundreds of days after the Miracle of the Mirage, the sky above the planet Moonlock was filled only with dust and color. While the occasional landed by and the odd satellite or station came briefly into view, the world was not--like many others in the system--a harbor for fleets or a rest stop for caravans. Perhaps, those on Moonlock thought, it was the planet's frightening proximity to Volition. Or maybe it was the tension of relationships on the surface, an awkward arrangement of Qui Err communities, NEH colonists, and of course, the militant "Particulars" who prowled the wastes looking for erratic phenomena to capture or destroy. It was not a particularly friendly world, Moonlock. So why should its skies be? But today, thousands of ships hang in orbit above the planet's capital city, the Sky Reflected In Mirrors. It is the Argosy, Spliced, flotilla of the NEH and the Church of the Self. And at the center of the fleet, is the Restitution of All Things, flagship of Our Profit, and current home to Fourteen Fifteen, errant member of The Notion. As Fourteen Fifteen goes about their business as a newly recognized citizen of the Hegemony, a twisting, clandestine ship slides past the many hundreds surrounding the Restitution: It is the Bolero Smooth, the awarding-winning vessel of Waltz Tango (Cache). And in its hold, deep in thought, is Grand Magnificent. He knows he has to rescue someone. But will it be his friend, or himself? This time on Twilight Mirage: The Restitution of All Things Pt. 1 I'ma try to swim from somethin' bigger than me Hosted by Austin Walker (@austin_walker) Featuring Art Martinez-Tebbel (@atebbel) and Jack de Quidt (@notquitereal) Produced by Ali Acampora (@ali_west) Cover Art by Craig Sheldon (@shoddyrobot) A transcription is available for this episode here.A full list of completed transcriptions is available here. Our transcriptions are provided by a fan-organized paid transcription project. If you'd like to join, you can get more information at https://twitter.com/transcript_fatt. Thank you to all of our transcribers!!
Helmet: Recorded & mixed by Branko Cosic Recorded at the Brightside, Brisbane, 30th April 2017 The original Helmet line up, consisting of Page Hamilton on guitar and vocals, Brisbane-born Peter Mengede on guitar, Henry Bogdan on bass and John Stainer on drums, formed in 1989 in New York City. Quickly signing to Amphetamine Reptile Records, they release their debut album Strap It On the year after. This led the band to be signed by Interscope Records in early 1992, with label mates including Primus, Nine Inch Nails, Dr. Dre and Snoop Dogg. Their first Interscope release Meantime (1992) was certified gold and remains Helmets biggest commercial success to date. Betty (1994) soon followed, bringing the band to our shores to play the now legendary Livid Festival 1994 line up featuring Beastie Boys, Superchunk, Frank Black and Tumbleweed. A falling out between Hamilton and Mengede in 1993 meant Peter didn’t make the trip out, but returned to reside in Brisbane in later years. This would be the first of many line up changes for the band, with Hamilton remaining the only constant member. Once touring Aftertaste over 1997-98, Helmet disbanded before reforming again in 2004 to release Size Matters. They have released a total of 8 studios albums and remain one of the most influential bands of the alternative rock movement. In 2017, Helmet returned to Brisbane for the first time since 2011, as part of their ‘Betty’ retrospective tour. This set features selections from the album as well as tracks from their latest LP Dead To The World and fan favourites from their lengthy back catalogue. Spliced in throughout the set is an interview conducted by Branko Cosic with founding member Page Hamilton.
This week we look at some automotive news coming from Subaru and Dodge. We also talk about the bad week of a GM employee and his driving ability (lack thereof). I also feature a great product, P3 Gauges, to spruce up your dashboard with a tuner's touch. Remember Buckle Up, Drive Hard but Drive Safe! Music Credits: On My Way by Alex (c) copyright 2013 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/AlexBeroza/42806 Ft: Donnie Ozone I dunno by grapes (c) copyright 2008 Licensed under a Creative Commons Attribution (3.0) license. http://dig.ccmixter.org/files/grapes/16626 Ft: J Lang, Morusque
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin The TWiPniks solve the case of the Man With AIDS, and explore how secretion of extracellular vesicles influences the social motility of Trypanosoma brucei. Become a patron of TWiP. Links for this episode: T. brucei exosomes and social motility (PLoS Path) Image credit Parasites Without Borders Letters read on TWiP 130 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase - WITH FREE SHIPPING - by going to blueapron.com/twip. Case Study for TWiP 130 Back in Peru. 24 yo female seen in ER, lives in rural area outside of big city, adobe house in highlands, thatched roof, dirt floor, 3000 meters. Quite ill with skin lesion for 48 h. 2 days before was pulling on pjs, felt sharp sudden pain in right upper leg. Next day found small living creature in pajamas, inguinal region. Developed red lesion, enlarged, developed black central dot. Then begins vomiting, comes to hospital. No fever, breathing fast 20, hr 70, bp 160/10, on exam see in right inguinal region an enlarging, necrotic area 1-2 cm, starting to look sick. Whites at 26000, left shift, 200 platelets, eosinophils 4%, bilirubin 3.5, creatinine 4.9 (going into renal failure, not making much urine). Hematocrit 14, BUN 59.7, CPK 227, RBCs and leukocytes in urine. No health problems, no surgeries, first interaction with health system. No toxic habit. Brings in the small creature! Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees
The One Word, Go! Show's 4th Annual Trick-or-Treatastic Halloweenathon continues with this year's spliced spooky story, where we each say a sentence and cut it together into a "coherent" story. Spoiler: It's not coherent. Keep listening all October long for more spooky extras and episodes! --- Submit your word! - Onewordgoshow.com Merchandise - Onewordgo.storenvy.com Voicemail Line - 1-844-OWG-SHOW // (1-844-694-7469) Twitter - Twitter.com/onewordgo Facebook - Facebook.com/groups/onewordgo Share:FacebookTwitterDiggRedditTumblrPinterestStumbleUpon
Carin Gorrell has been Editor in Chief of Yoga Journal since December, 2013. Prior to that she was the features director of Self magazine, the health editor at Redbook and a senior editor at First for Women and Psychology Today. She has directed a cover-to-cover redesign of Yoga Journal, creating new departments and columns to cover the yoga world in all its depth and breadth and addressing controversial topics trending in the yoga community. The new design earned the magazine a Maggie Award for Best Health & Fitness Consumer Magazine and a Nichee Award for Best Niche Consumer Magazine in 2015. We spoke of her ideas and plans for American yoga’s signature publication. Learn more about Carin Gorrell and Yoga Journal here: http://www.yogajournal.com/about_us/g
The One Word, Go! Show's 3rd Annual Trick-or-Treatastic Halloweenathon continues! Join Mat, Dan, Andrew, and Mélissa as they make up a spooky story on the spot about two young boys named Sven and Billy who get confronted by a mage and his wildebeest. Stay tuned all throughout the month of October, where we'll be posting ridiculous Halloween-themed "special" episodes all month long! Subscribe in iTunes so you don't miss a thing! --- Submit your word! - Onewordgoshow.com Merchandise - Onewordgo.storenvy.com Voicemail Line - 1-844-OWG-SHOW // (1-844-694-7469) Twitter - Twitter.com/onewordgo Facebook - Facebook.com/groups/onewordgo The One Word, Go! Show is an affiliate of The Webcast Beacon Network Share:FacebookTwitterDiggRedditTumblrPinterestStumbleUpon
The One Word, Go! Show's 2nd Annual Trick-or-Treatastic Halloweenathon continues! This time, Mat, Dan, Fish, Andrew, and special guest Kevin, write their very own Halloween story! Halloween themed extras will be posted all October long! --- The One Word, Go! Show is a proud affiliate of The Webcast Beacon Network! Submit your word! - Onewordgoshow.com Merchandise - Onewordgo.storenvy.com Voicemail Line - 206-337-5302 Twitter - Twitter.com/onewordgo Facebook - Facebook.com/onewordgo Share:FacebookTwitterDiggRedditTumblrPinterestStumbleUpon
Spliced mice and oral HIV vaccines by Ian Woolf, Dr Jodi Rowley from the Australian Museum Research Institute talks about her search for rare amphibians at Inspiring Science, Gemma Sharp's Three Minute thesis: "Paying for Lip Service", Production checked by Charles Willock, Produced and hosted by Ian Woolf Support Diffusion by downloading a free audio book from http://www.audibletrial.com/science
Join a Cuau-less Edgar and Josh as they discuss what movies they've recently watched and hear them review this weeks movie Spliced also known as The Wisher.
It's evil week on the podcast and we're looking at the dark side of getting things done. We'll help you become a productive dictator, get out-of-warranty repairs, free internet, and the best cheap pizza you can microwave. Looking for the show notes? You can find this episode at http://lifehacker.com/5951115 (after 5:00 PM PT) and all episodes at http://lifehacker.com/theshow (anytime). See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The human complement factor H is an important component in the control of the alternative pathway of complement activation. We have previously shown that at least three factor H homologous mRNA species of 4.3 kb, 1.8 kb and 1.4 kb in length are constitutively expressed in human liver. In addition, several factor Hrelated proteins have been detected in human sera using antibodies directed against the classical human factor H glycoprotein of 150 kDa.The structure of the additional polypeptides has not been shown so far. Circumstantial evidence suggests that the 1.8-kb mRNA might encode the 43-kDa factor H-like polypeptide. Here we report the isolation, characterization and eukaryotic expression of the first full-length cDNA representing the major 4.3-kb mRNA and the 1.8-kb mRNA of human factor H. We show that the 4.3-kb transcript encodes the 150-kDa-factor H glycoprotein and the 1.8-kb mRNA the 43-kDa factorH polypeptide. The identity of the two cDNA in a region of 1400 nucleotides suggests that the two factor H-related transcripts are derived from one gene by a process of alternative splicing.
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