Podcasts about results no

Are you ready to embark on a journey to enhance your self-esteem? Dive deep into your subconscious while you sleep to rewrite the programming of your mind, because you deserve to feel great. During this subconscious sleep reprogramming, you will hear and internalize positive affirmations. As your conscious mind drifts off to sleep, your unconscious mind will absorb these affirmations, just like planting a seed in fertile soil. By implanting these thoughts deep into your subconscious, you'll wake up feeling revitalized, refreshed, and ready to face the day. Are you prepared? Make this a daily practice for optimal results.

New York's presidential primary went under the radar as the suspense of the race fades. Also, the No Label party opts not to run.

Happy Easter! Dr. John R.Lott from Crime Prevention Research Center. Biased AI results? NO!

Today is a big day for us and for golfers everywhere! 18,130 shots later, we can finally reveal the #1 Driver of the season! 37 Drivers tested and over 420 hours of research put into finding the best for your bag. Tony and Chris are diving deep into what's new for Most Wanted scoring and who came out on top for Distance, Forgiveness and who released the most accurate driver of the year! Let's get it! CLICK MORE

The final year of the four-team College Football Playoff joins the inaugural year as the only two seasons in which a Southeastern Conference team didn't play in the national championship game. Is the matchup between the Michigan Wolverines and Washington Huskies good or bad for the sport? Relive the greatest season in Tennessee football with behind-the-scenes stories about the 1998 National Championship Team. Click below for Celebrate '98: The Untold Stories Behind the Tennessee Vols' 1998 National Championship. Available in soft and hard copy. Personalized, autographed copies available! https://shop.offthehooksports.com/ SUPPORT OUR SPONSORS  Andy Mason Elite Realty Real estate experts with over four decades combined experience in East Tennessee. Best prices. Best service in the Knoxville area. https://www.andymasonrealestate.com/ Apex Apparel Group Design. Brand. Market. Your Way! Unique products to promote your business with unparrelled customer service. https://apexapparelgroup.com/ Brainerd Golf Course and Brown Acres Golf Course Golf Chattanooga's best public courses. Tee times available! Just click below. https://secure.east.prophetservices.com/ChattanoogaV3/(S(bulxf3daupdyu2kxqnwdabs2))/Home/nIndex?CourseId=2,1&Date=2023-5-3&Time=AnyTime&Player=99&Hole=Any Campbell Cunningham Taylor and Haun Enjoy Life Better When You See Better! LOCAL vision service for Lasik, cataract surgery and regular eye examination. https://www.ccteyes.com/ Chatt Mortgage Congratulations! Your home search just got easier. Buying a home in Chattanooga has never been easier with Chattanooga Mortgage. https://chattmortgage.com/ City Heating and Air 50 years in East Tennessee. Integrity Matters! Don't trust a fly-by night HVAC company to tell you that you need a new unti that could cost thousands or more. http://www.cityheatandair.com Dynasty Pools and Spas Imagine having the best spas - made right here in the USA - in your backyard. Well, they're here! Now open, Dynasty Pools and Spas has their brand new showroom open in Athens with the best hot tubs and spas on the market. Delivery? Yes, they can do that. Complete support, spa cover and chemicals to keep your spa bubbling at it's best. That's Dynasty Pools and Spas. Amazing discounts for first responders, military and even some blemished models that can save you a ton and no one will ever notice. Dynasty Pools and Spas! Go to dynastyspas.com or stop by there incredible new showroom in Athens. Dynasty Pools and Spas. Harrell Group Security Solutions Leadership. Experience. Specialization. Addressing problems through unique, mission specific mitigation techniques. Also, making your children safer one school at a time. https://www.harrellgrp.com/ Hemp House The premier hemp dispensary online with a wide variety, great selection and strict standards to ensure you only receive the best in CBD or Delta products. https://hemphousechatt.com/ Meridian Insurance Covering Your World. Are you paying too much for insurance. Probably so. Click below for a free quote. https://www.chandahasyoucovered.com/ Rick Terry Jewelry Designs We want to be your Jeweler! Looking for affordable game-day jewelry. How about the fire opals? A Tennessee tradition. https://rickterryjewelry.com/ Sport Treasures Carrying Over 5-million Sports Treasures….and so much more! Follow on Facebook for the best sports memorabilia. Daily updates! https://www.facebook.com/SportsTreasuresTn/ Sports Clips It's a game changer! Everyone needs the MVP treatment! Use promo code 2500 for $3 off! https://sportclips.com/us-tn-chattanooga-tn501?utm_source=SOCi&utm_medium=GMB TN Cider Company The original hard cider of the Smoky Mountains. Use the promo code “HAT” to receive some free sway with your cider order. Available most anywhere in the U.S. https://www.tncidercompany.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

When we assigned each of our members their own individual coach, I thought it was the best idea we had ever come up with. And it absolutely flopped. We had created an adult babysitting service. In this episode, I share how you can empower your clients, not cripple them by making it so easy they don't have to do anything themselves. BOOK A FREE 15-MINUTE CONSULTATION CALL TO START, GROW OR SCALE YOUR ONLINE FITNESS BUSINESShttps://vincedelmonte.ca/pccall

Contributor: Jared Scott MD Educational Pearls: Should we use opioids to treat low back and neck pain? The OPAL Trial, published in The Lancet, in June 2023, attempted to answer this very question. Objective: Investigate the efficacy and safety of a short course of opioid analgesic (oxycodone-naloxone) for acute low back pain and neck pain. Trial Design: Triple-blinded, placebo-controlled randomized trial, conducted in Emergency and Primary Care in Sydney, Australia, involving adults with 12 weeks or less of low back or neck pain. Participants: 347 recruited adults (174 in the opioid group, 173 in the placebo group) with at least moderate pain severity. Intervention: Participants were assigned to receive either an opioid or a placebo for up to 6 weeks. Primary Outcome: Pain severity at 6 weeks measured with the pain severity subscale of the Brief Pain Inventory (10-point scale). Results: No significant difference in pain severity at 6 weeks between the opioid group (mean score 2.78) and placebo group (mean score 2.25). Adverse events were reported by 35% in the opioid group and 30% in the placebo group, with more opioid-related adverse events in the opioid group (e.g., constipation). Conclusion: Opioids should not be recommended for acute non-specific low back pain or neck pain, as there was no significant difference in pain severity compared with the placebo. The study calls for a change in the frequent use of opioids for these conditions. Pharmacy Pearl: Why was naloxone mixed with oxycodone? Naloxone is an opioid receptor antagonist, meaning it can block the effects of opioids. When combined with oxycodone, naloxone's presence discourages certain forms of opioid misuse. Additionally, naloxone can bind to opioid receptors in the gut and improve symptoms of Opioid Induced Constipation (OIC). This is the same idea behind Suboxone (buprenorphine/naloxone).   References Jones CMP, Day RO, Koes BW, Latimer J, Maher CG, McLachlan AJ, Billot L, Shan S, Lin CC; OPAL Investigators Coordinators. Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial. Lancet. 2023 Jul 22;402(10398):304-312. doi: 10.1016/S0140-6736(23)00404-X. Epub 2023 Jun 28. Erratum in: Lancet. 2023 Aug 19;402(10402):612. PMID: 37392748. Camilleri M, Lembo A, Katzka DA. Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits. Clin Gastroenterol Hepatol. 2017 Sep;15(9):1338-1349. doi: 10.1016/j.cgh.2017.05.014. Epub 2017 May 19. PMID: 28529168; PMCID: PMC5565678. Summarized by Jeffrey Olson MS2 | Edited by Jorge Chalit, OMSII  

#lakeforestillinois #lakeforestpodcast #petejansons #lakeforestsurvey Pete Jansons, Joe Weiss and Rick Lesser Discuss Lake Forest Illinois Hyper Local Topics 0:00 1:33 Pre Show 3:14 School Teacher Contract agreed upon so easy 17:03 Israel 31:30 Lake Forest Survey Results put card up 44:57 Heart of Glass Blondie Tribute Show Schaumburg October 28 7:30pm 49:00 Joe Weiss Addresses City Council re Elawa Farm 56:22 Lake Forest homeless update --- Send in a voice message: https://podcasters.spotify.com/pod/show/lakeforestpodcast/message Support this podcast: https://podcasters.spotify.com/pod/show/lakeforestpodcast/support

Top-performing CISOs shared with me their hacks for creating a team atmosphere, getting excellent and consistent results, and creating buy-in from management for their budgets, projects, and big ideas. This discussion goes beyond risk management into the realm of performance excellence. Impact Leaders Pod Training for Cyber Teams is a unique 8-week program to up-level performance in information technology professionals and teams. Participants grow leadership, emotional intelligence, teamwork, and performance excellence while excelling at their daily job responsibilities. For more information contact Steve or visit impactleaderscoaching.com Visit https://securityweekly.com/csp for all the latest episodes! Follow us on Twitter: https://www.twitter.com/cyberleaders Follow us on LinkedIn: https://www.linkedin.com/company/cybersecuritycollaborative/ Show Notes: https://securityweekly.com/csp-137  

[This episode is available on Video Podcast via YouTube] Have you ever wondered why sometimes it feels like you just keep falling back into the same cycles and patterns? No matter how hard you try, what new approach you take or how many changes you make- it's like you just keep winding up with the same results?  In this weeks podcast episode, "Why you keep getting the same results, no matter how hard you try: Paradigms, Principles & Beliefs" I talk about what creates these perpetual experiences in our lives.  Our paradigms are the lens through which we view the world and take actions from. Our principles are the beliefs that reinforce those paradigms. And our beliefs are shaped through our conditioning.  When we can understand how our principles are dictating our results, we will begin to become more conscious of what principles we are operating by. Sometimes the principles we uphold are outdated or no longer serve what we value- thats why its important to do a regular audit of them! Key takeaways: What creates your paradigm of life? The role of principles in creating results - How values affect your choices Exploring the money principle: money is hard to make An alternate way to view creating results quickly Values based living is about sustainability! If you enjoyed this episode get in touch with me & stay in my world on Instagram @_nicolaaay Chat soon! Curious about working with me? Here are the ways we can work together:  ✨[GROUP PROGRAM] 12 weeks of embodying the best version of you. Join myself & an intimate group of women on an intentional journey towards self discovery, re-alignment & equipping. The goal of this program is to help you take back ownership over your life & upskill with the tools to be able to confidently navigate your own mind and emotions no matter what life throws at you. From this program, you'll walk away clear & confident on how to live a life aligned to what you value & how to be free from the external pressure to be anything than your authentic self. This is about liberation FROM THE INSIDE OUT. Apply for the next round here. ✨ [PRIVATE MENTORSHIP] Are you a high functioning woman in business who's tired of hustling your way to results? Stop trading what you value for results. Learn how to build your business in FLOW. Apply for my 6mo of private coaching with me. Click⁠ here⁠ to book a FREE CONSULTATION where I'll show you exactly what a custom roadmap could look like for you to go from building a business that runs you to one that supports you and the freedom-based life you want.

Whether you're at home, on the road, or just do not have access to workout equipment, this Physical Friday is just for you. Today we go over the COUNTDOWN WORKOUT. Often called 11s or 21s, all you need for this workout is two exercises! Let's use PUSH-UPS and SQUATS as an example. Start by doing 10 push-ups. After those 10 reps, do 1 squat. Then you will do 9 push-ups and 2 squats. Next do 8 push-ups and 3 squats. Repeat these steps until you finish with 1 push-up and 10 squats! If this is too easy, increase the reps to something more challenging (11, 21, 31...)! Let us know how you like this workout! Tag @tom_rowland_podcast and @tomrowland and share your progress. Join the Black Rifle Coffee Club and get 25% Off Your First Month by Using BLASTOFF25 For the supplements and nutrition Tom uses click here For my favorite electrolytes click here Salt Strong Insiders Club: https://bit.ly/RowlandMembership Learn more about your ad choices. Visit megaphone.fm/adchoices

Meet Michelle, She joined The Mentorship Program last year. Before... Suffered: Chronic Fatigue Syndrome Symptoms: Extreme fatigue, symptom flareups, brain fog, and cognitive issues. Struggles: Non- acceptance, loss of identity, mum guilt, pushing & crashing, no energy, self-doubt, no boundaries/people pleasing After... Results: No more mum guilt, aligned mum, more energy, stabilised health, no more pushing & crashing, living life fully, changing life path. If you want to find out how mother of one Michele went from suffering daily to overcoming Chronic Fatigue Syndrome and living fully, click below to watch her full interview. Click here for the transcript Here are 4 ways we can help. 1. Join our free community to meet others, be inspired, and get more recovery info - https://www.facebook.com/groups/cfshealthrecoveryhub 2. Watch the newly released past members "Guest Panel" Workshop where they share their top 5 recovery secrets - https://www.cfshealth.com/guestpanelreplay 3. Get our free most popular recovery trainings:- Find your baseline - Stop pushing and crashing - https://www.cfshealth.com/baseline - The 3 stages of recovery and what to do in each one - https://www.cfshealth.com/the3stages - The "9 do's and don'ts" PDF - to decrease symptoms and improve energy - https://www.Cfshealth.com/pdf 4. Want help professionally with a step-by-step recovery plan specific to you? Fill out the application form and the team will send you the details - https://www.cfshealth.com/form

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.10.527999v1?rss=1 Authors: Bailey, N., Baell, O., Payne, J., Humble, G., Geddes, H., Cahill, I., Hill, A. T., Chung, S., Emonson, M., Murphy, O., Fitzgerald, P. Abstract: Objectives: Mindfulness meditation (MM) is suggested to improve attention. Research has explored this using the 'attentional-blink' (AB) task, where stimuli are rapidly presented, and a second target stimulus (T2) is often missed if presented ~300ms after an initial target stimulus (T1). This research showed improved task-accuracy and altered neural activity after an intensive 3-month MM retreat. We tested whether these results replicated in a community sample of typical meditators. Methods: Thirty-one mindfulness meditators and 30 non-meditators completed an AB task while electroencephalography (EEG) was recorded. Between-group comparisons were made for task-accuracy, event-related potential activity (posterior-N2 and P3b), theta and alpha oscillatory phase synchronisation to stimuli presentation, and alpha-power. Primary aims examined effects within time windows reported by previous research. Additional exploratory aims assessed effects across broader time windows. Results: No differences were detected in task-accuracy or neural activity within our primary hypotheses. However, exploratory analyses showed posterior-N2 and theta phase synchronisation effects indicating meditators prioritised attending to T2 stimuli (p less than 0.01). Meditators also showed more alpha-phase synchronisation, and lower alpha-power when processing T2 stimuli (p less than 0.025). Conclusions: Our results showed multiple differences in neural activity that suggested enhanced attention in meditators. The neural activity patterns in meditators aligned with theoretical perspectives on activity associated with enhanced cognitive performance. These include enhanced alpha 'gating' mechanisms, increased oscillatory synchronisation to stimuli, and more equal allocation of neural activity across stimuli. However, meditators did not show higher task-accuracy, nor did effects align with our primary hypotheses or previous research. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Join Our private Facebook community https://www.facebook.com/groups/mensfatloss/   Today's episode is something that is not spoken about enough when it comes to getting results and the truth. This could be why you've never set healthy fitness habits and still continue to struggle. We have trainSHARPE'S MVP, our head coach Leigh on the show today and he lays out the truth from his personal experience and the root cause of the long-term struggle.    

I did an episode a long time ago on this, people got results, I was over the moon! So once again, enjoy!

In todays episode I jump on with Vassil, our Mindset Coach in GCA and we talk about how to break free of your past and choose values that make getting results easy and consistent.Check out Vassil: https://www.instagram.com/vassil_karamanov/Apply for Coaching: fritzhorstmann.comMore helpful content for your plant-based journey:1. Get access to my free Video Course - Fit Vegan Masterclasshttps://www.fritzhorstmann.com/free-course2. Join my free Facebook Group: Plant-Based Fitness Secrets - and you'll get my Fit Vegan Cookbook for free: https://www.facebook.com/groups/pbfitnesssecrets3. Follow my instagram for short & value packed content: @fritz_horstmann - for high level plant-based fat loss & muscle gain content@fritz_nutrition - for plant-based nutrition and recipe content@gamechanger_academy - for client results & testimonialsIf this was helpful for you, please consider subscribing and leaving a 5-Star Review on iTunes, so I can bring more amazing guests on to the show.Peace, Love & Vegainz!- Fritz

Dielle talks with Five Figure Freedom client Rhonesha Bontemps about the success she's had. Rhonesha took personal responsibility for her results, and she shares the strategies she used to make Five Figure Freedom work for her, even as a busy wife and mom.   Follow Dielle @diellecharon

More than 64 000 new COVID infections were detected around the country yesterday, another all-time high for Australia and some analysts are predicting they could reach the hundreds of thousands. The federal government has moved to scrap PCR tests to confirm new infections as its ability to accurately count cases is put to the test.

Australian News: 05 January 2022 – Wednesday Read by Selvi - ஆஸ்திரேலிய செய்திகள்: 05 ஜனவரி 2022 புதன்கிழமை வாசித்தவர்: செல்வி  

After our 1972 episode, we asked you to vote for the songs that you thought were worthy of the Hall of Songs. After that election ... we have results. But we're not giving anything away. Not this time! (You'll have to listen to find out more.)That said, we will say that a few songs that we expected better of are either off the ballot or very close to their end. Which songs? Again, you'll have to listen.Host: Timothy MalcolmHost: Christopher JonesMusic commentary and music history

The EFF have voted for the DA in all the councils - what is going on? What does this mean? Let's analyze.. Website: https://morningshot.co.za/ Merch: https://morningshot.co.za/store/ Coffee: https://morningshot.co.za/store/250g-Morning-Shot-Espresso-p390028965 Facebook: https://www.facebook.com/MorningShotZA Twitter: https://twitter.com/MorningShot1 Sources: https://www.news24.com/witness/news/ifp-withdraws-support-of-anc-at-ethekwini-20211122 https://www.news24.com/news24/southafrica/news/despite-having-no-coalition-agreement-the-da-scores-surprise-mayorship-of-joburg-20211122 https://www.news24.com/news24/southafrica/news/shocked-but-ready-for-the-job-ekurhuleni-mayor-tania-campbell-to-extend-hand-to-opposition-20211122

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281 Friday Rant: Process vs Results No guests. No script. #FridayRant on Construct Your Life Podcast. Subscribe to the show on your favorite podcast player today!! #rant

The AIDIF guys are joined by podcast host and 2x Olympic snowboarder Aimee Fuller. To discuss the physical and mental pressures of elite-level sport. In the news, the guys discuss school exam results, Kanye not dropping Donda, and Scarlette Johanson suing DisneySupport the show (https://www.patreon.com/aidifpod)

EP 2191 Jeff Altman, The Big Game Hunter offers more advice for creating resumes that get results. SUPPORTERS: Fiverr https://thebiggamehunter.us/fiverr Hire a freelancer. Do freelancing. Fiverr makes it easy to do both. I use it regularly. Maybe I'll wind up hiring you! Incorporate https://thebiggamehunter.us/incorporate If you start freelancing or a business, you need to follow the law. Incorporate makes it easy to set up your business legally. ABOUT JEFF ALTMAN, THE BIG GAME HUNTER Jeff Altman, The Big Game Hunter is a coach who worked as a recruiter for what seems like one hundred years. His work involves career coaching, as well as executive job search coaching, job coaching, and interview coaching. He is the host of “No BS Job Search Advice Radio,” the #1 podcast in iTunes for job search with more than 2100 episodes. Are you interested in 1:1 coaching, interview coaching, advice about networking more effectively, how to negotiate your offer or leadership coaching? Schedule a discovery call at my website, www.TheBigGameHunter.us Learn to interview like a pro. "The Ultimate Job Interview Framework" www.TheBigGameHunter.us/interviews Kindle and print versions are available on Amazon. Classes On Skillshare https://thebiggamehunter.us/Skillshare Become a freelancer or hire one on fiverr.com https://thebiggamehunter.us/fiverr. I use it and I may wind up hiring you! To set up your freelance business correctly, you may want to incorporate https://thebiggamehunter.us/incorporate Join Career Angles on Facebook and receive support, ideas, and advice in your current career and job. Connect with me on LinkedIn www.linkedin.com/in/thebiggamehunter Mention you listen to the podcast or watch my YouTube channel. If you are starting your search, order, “Get Ready for the Job Jungle” on Amazon. Job Search Going Nowhere? "Diagnosing Your Job Search Problems" for Kindle on Amazon and receive free Kindle versions of "No BS Resume Advice" and "Interview Preparation. Watch my videos on YouTube at JobSearchTV.com, the Job Search TV app for Roku, fireTV or a firestick or Bingenetworks.tv for Apple TV, and 90+ smart tv's. Since 2007, FlexJobs has been the #1 site for work at home opportunities www.TheBigGameHunter.us/flex Thinking of making a career change and need some ideas that fit you. CareerFitter offers a free test and if you want more you can upgrade for the paid version.https://thebiggamehunter.us/Career --- Support this podcast: https://anchor.fm/nobsjobsearchadviceradio/support

For episode 82 Raphael speaks to online fitness business owner Azarria White (Twitter: @Azarria_White Instagram: @AzarriaWhite website: FitnessWithZ.com) about the importance of entrepreneurs scheduling their meals, how everyone is NOT your clientele, investing big for big results, getting clear on what you want, removing emotion from your business, getting comfortable with being uncomfortable, and much more! Black Billionaire Banter: Pharell Williams' partnership with Amazon & Georgia Tech for the "Your Voice is Power" initiative Pick up the brand-new ebook from the creators of Tweet Talk, "Don't Be A Little B*!" ebook at https://gumroad.com/l/DontBeBook NEW courses: Understanding My Taxes: Individuals, Understanding My Taxes: Stock and Options Trading, Maximizing Opportunities in Mutual Funds (and ETFs) Be sure to join the Todd Capital Business Development Mastermind Group Pick up the carryall duffle bag from the brand new luggage brand, Views, launched by Tweet Talk co-host Charles. Follow us on social media: Twitter- Charles @RealToddBillion Raphael @WorkMoneyLife Instagram: Podcast- @TweetTalkPodcast Charles- @ToddBillion @Todd.Capital @BlessABlackMan Views Luggage brand @views.at.todd.capital Learn how to make money trading stock options, from Todd Capital! This show's sponsors: Premium shoes need premium shoelaces from Get Laced Laces at GetLacedLaces.com All-natural body care products from Pure Body Co at ShopPureBodyCo.com Okiyefa Shades- The finest shades to fit your style: OkiyefaShades.com --- Send in a voice message: https://anchor.fm/tweettalk/message Support this podcast: https://anchor.fm/tweettalk/support

It's another Wellness Wednesday episode and Momma... I'm sharing some amazing tips and tricks to help you easily fuel your body daily in a healthier way without dieting or food prepping! WHATTT??!! Oh yeah you read that right! I know you already have a lot going on everyday, and finding ways to eat better can be an inconvenience and sometimes even feel a bit difficult. Join me as I help guide you on healthy ways that will fuel your body, simplify healthy eating, and make your life a whole lot easier! Happy listening.If you loved this episode please subscribe and leave a great review on ITunes or Apple Podcast.  Thanks for listening! Connect with me: Instagram: msreneseyvetteFacebook: Renese YvetteE-mail: reneseyvette@gmail.comWebsite: abundantlyempoweredyou.com

At exactly four months, I am now at a place where I can record another podcast episode. So much has happened in these past months.... In this episode I will remind you of ways of checking in with yourself. I will share with you a few personal things that happened in my life. I will mention events that unfolded in the United States. I will also share four tips for making it through the rest of this year healthy. Finally, I will thank each of you for listening to this podcast and ask you to join me for season 2. --- Send in a voice message: https://anchor.fm/lovelylincke/message

No Name NonSense Podcast Our thoughts on the Election and Pres. Trump Email: HCannonC@gmail.com Instagram: @DJTunez25; @Ricardo77Marti; @jas.b.allen Facebook and YouTube: Head Cannon Circus Spotify Playlist: DJ Tunez & Corny J DSP: Head Cannon Circus --- Support this podcast: https://anchor.fm/jason-allen10/support

For those of us who have already voted, and for those who are casting our ballots today, how are we looking at this year's election? Are we viewing it through the framework of faith, hope and love in a Savior who holds everything together and is sovereign over all things? Tuesday on Mornings with Eric and Brigitte, Pastor of City Rev Church in Pembroke Pines, Robey Barnes joins us to remind us that whatever the outcome of today's election, God is in control. City Rev Life Podcast See omnystudio.com/listener for privacy information.

In this episode you'll learn about…Discomfort and talking TED. (1:47)Commit yourself so deeply there's no turning back. (6:47)Two lessons learned from his first keynote. (14:17)The true Adventure Man. (23:06)Balancing Surrender & No Matter What. (29:47)What discomfort is Sterling hunting? (34:53)

Jimmy Barrett and Shara Fryer take you through the stories that matter on the morning of 06/18/2020. Voters won't accept the 2020 election results — no matter who wins. Joining Jimmy and Shara to discuss the issue is Political strategist Chris Wilson, President and CEO of WPA Intelligence. We’re all wondering, when will things start to feel “normal” again? Now imagine running a business that relies heavily on in-store foot traffic to hit sales goals and projects, and think about how anxious they are to have that question answered. Calling in to talk with Jimmy and Shara is Trae Bodge.Political analyst Chris Begala calls in to talk about The Trump Pollster John McLaughlin: Mainstream Media Polls ‘Skewed’ to ‘Water Down the Trump Vote’.

https://www.johnelite.com www.johnelitedating.com

Should the phrase "no pain, no gain" be your training motto?

This week on How to Love Your Body we are going to be talking about HEALTH and how to navigate it without it being rooted in diet culture. This week’s episode is brought to you by The UnDiet Academy - the 13 week group coaching program that brings you from dieting, binge eating, and thinking about food all day to living as an intuitive eater and finding wellness without the obsession. Doors are open now but they close on Wednesday (tomorrow!) at 6 pm pacific. This will not be happening again until mid next year!   Now let’s dive into today’s episode! Many women we talk to want health, wellness, energy, to FEEL GOOD, but they aren’t sure how that happens with intuitive eating and undieting without them slipping back into old dieting habits. Here’s how it works: There are 5 vital phases to go through to get to this place of balance and wellness without the obsession.   Phase 1 : The initial exit - This is where you are now - dieting, off the diets but not feeling great about it or immersed in intuitive eating and dieting CONTENT but not feeling like it’s clicking. The results? YOU ARE AWARE OF AN ALTERNATIVE. Awareness is always the first step. You are ready to stop the cycle and start this process! Phase 2: The diet mentality detox: Thinking as a dieter will always have you behaving as a dieter. WHen you begin to think differently you end up NATURALLY acting differently which is how transformation begins.  Trying REALLY HARD not to eat the whole box of cookies isnt freedom, finding that you’ve forgotten about that box of cookies for a few days IS the beginning of freedom. Phase 3: The inner self work - you probably already know the struggle with food and body is about MORE than the food you’re eating or the body you’re in. Working on deeper healing like - self worth, body image, self love, and finding genuine happiness and contentment in the life you have NOW, needs to happen in order to find peace with food. Inner peace allows you to let go of the desperation of trying to FIX yourself through diets etc. Phase 4: Embodying intuitive eating --  NOW is the time to begin focusing on actually eating food :) . Once you’ve done the mindset work and the inner work -- you can learn how to EMBODY intuitive eating, not have it just turn into another way of eating that you’re thinking about all day long. Results: No longer having to listen to every podcast, be in every free FB group, because you don’t think about food much anymore, OR intuitive eating, you dont need to think about it when it just occurs! It just HAPPENS! And that is true transformation. Phase 5: Wellness without the obsession - Here is where we get into today’s main topic. HEALTH --  Where does that come in?  Okay I’m thinking differently, and I have done some deeper work - I still have these health issues, how can I deal with them without going on a diet or feel restricted? THis is where phase 5 comes in - yes physical health is important to many people and if it’s something important to you then this is definitely a process you’re going to want to go through. Wellness without the obsession is all about implementing positive health behaviours REGARDLESS OF YOUR BODY SIZE. Why does this distinction matter? When you focus on weight it takes away the inherent value of the health behavior you’re trying to practice more of. Moving your body more but it doesn’t result in weight loss - WHAT’S THE POINT?? Of course there’s a point but if weight loss is always the goal - we get frustrated and we stop things that could be great for our physical wellness. “Research show, positive health behaviours regardless of body size, can reduce mortality risk to the point where there is NO difference between those in smaller or larger bodies” - Andrea Hardy RD So what are positive health behaviors that I can expect to have in my life once I go through the 5 phases and find wellness wihtout the obsession? Getting enough sleep Eating nourishing foods of all different kinds Having a healthy relationship with food free from binge eating, food obsession and body shame Taking care of your mental health Prioritizing feeling good in your body Moving your body Enjoying life without the constant chatter of should I eat this, I shouldn’t have eaten that running through your mind If you are knowing at this point that dieting is not going to work for you and not dieting feels pretty crappy too - wellness wihtout the obsession is likely just what you have been looking for. We’d love to help you get there.   If that sounds like something you want more information on don’t forget to take a look at The UnDiet Academy - our 13 week program to bring you from being stuck in just NOT DIETING and not feeling good in your body to TRULY embodying intuitive eating and have this whole food and body struggle be OVER! Doors close tomorrow at 6 pm pacific so go take a look now to see if its the right fit for you at thebodylovesociety.com/undiet

Episode Notes CommuniD The Podcast -Episode #20 _Abundant Results; No Cape Required_Frank McGhee has decades of impactful work with youth in Detroit. He often commands attention being mistaken for a minister or law enforcement type. Yet, there is no mistake that he is dedicated to helping youth overcome societal encumbrances... to Thrive. Listen as Audra chats with her CT Alum for a powerful dose of encouragement.CommuniD is hosted by Audra Carson the founder and leader of Izzie LLC. CommuniD is produced by Val Ward.

Popcorn Talk Network proudly presents a vodcast for your insider look into the day to day reporting of the hottest scoops, exclusives and reports from the leading reporters in the industry on all things movie news! It's Popcorn Talk Network's Meet the Movie Press, hosted by Forbes's Simon Thompson and friends! They will discuss the ever changing landscape of movie news and trade reporting. With discussions on everything from Marvel casting to landing exclusive stories on major Hollywood tent-poles. Movies The Upside A Dog’s Way Home Replicas News Globes Results For The First Time in Thirty Years, The Oscars Won’t Have a Host; The Avengers Might Assemble to Present at This Year’s Host-Less Oscars BAFTA Nominations The Favorite Leads With 12 John Lasseter is Now in Charge of Skydance Animation ‘Dune’ Will Reunite Dave Bautista With Denis Villeneuve as Beast; Stellan Skarsgard Boards Denis Villeneuve’s ‘Dune’ as Villain Baron Harkonnen ‘Venom’ Sequel Confirmed, Kelly Marcel Returning to Write, But Ruben Fleischer Won’t Direct Jordan Peele’s ‘Us’ Will Have Its World Premiere at 2019 SXSW Film Festival The Margot Robbie ‘Barbie’ Movie is Officially Happening as Warner Bros. Finalizes Deal With Mattel Brad Bird’s Next Project is an Original Live-Action/Animated Hybrid Musical With Michael Giacchino ‘Space Jam’ Sequel ‘Skate Jam’ Almost Happened, Starring Tony Hawk ‘Aquaman’ is Now the Highest Grossing DCEU Movie Follow @ShowBizSimon for Simon Thompson! Follow @DMovies1701 for Demetri Panos! Follow @TheOtherScottM for Scott Menzel! Subscribe to the podcast on iTunes! Make sure to subscribe to Popcorn Talk! - http://youtube.com/popcorntalknetwork HELPFUL LINKS: Website - http://popcorntalk.com Follow us on Twitter - https://twitter.com/thepopcorntalk Merch - http://shop.spreadshirt.com/PopcornTalk/ ABOUT POPCORN TALK: Popcorn Talk Network is the online broadcast network with programming dedicated exclusively to movie discussion, news, interviews and commentary. Popcorn Talk Network is comprised of the leading members and personalities of the film press and community including E!’s Maria Menounos. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

In this week's Beltway Beef podcast, NCBA's Senior VP, Government Affairs, Colin Woodall, reacts to Tuesday's midterm election results - both what they may mean in the upcoming lame-duck session and when Democrats retake control of the U.S. House in January.

Investing Fundas with Aditya Shrimankar is a weekly podcast that will help keep you abreast with investment ideas/economic data/business news etc. from India and abroad. The information is presented in a succinct manner helping you to get the essence of all the important bits in just a few minutes. This episode features the following: - Monopoly Lies - Big results with tiny improvements - No one is crazy - Start-up idea of the week - Mutual Fund Tip of the week

Want to get really big breakthroughs changes in your life, in a way that's filled with ease and grace? Do you keep quitting, even though you want to change? There's often a lot of things we don't see that are holding us back from making the changes in our lives that we'd like to see. … Continue reading BREAKTHROUGH RESULTS? NO SWEAT — Ep. 20 →

Welcome back for a 3rd appearance Aaron Dokos! If you haven't been keeping up with Aaron, he's recently had his knee replaced and he joins us on the show today to talk about what he's learned both mentally & physically through that process. He always is evolving at a fast rate so tune in and get ready for some serious knowledge bombs to be dropped today! https://www.facebook.com/groups/SantiagoDOKOS/ I'm participating in the Mark Divine's Courage Foundation BURPEES FOR VETS challenge to support their programs for veterans with PTS. I've committed to doing 100,000 burpees in 2018! I am pledging $0.02 for every burpee I do.  Check out my fundraising page and please consider making a donation or pledge per burpee to help me reach my goal of $25,000!!! Support Kenyon's Goal of Raising $25,000 for Veterans! Support the show by visiting our sponsors and affiliates!!! See all our recommended books and products in our Amazon shop: https://www.amazon.com/shop/zeroxcuses Are you looking to band together with like-minded alpha males who are looking to build discipline, regain control of your time, build wealth and ultimately live life on your terms? We have recently launched the Infinite Results Mastermind where you can do just that. If you are interested in committing to getting exactly what you want in your life then join us at the link below: Infinite Results Mastermind Are you looking to build rock-solid discipline? Regain control over your time? Build your bank account? Connect on a deep level with your family? If so and you're willing to invest the time, money and energy into reaching your goals checkout my discipline coaching program! I teach you the fundamental tools, strategies and tactics necessary to have discipline in every area of you life! It's by application only and I only have a few spots for this! Discipline Coaching Connect with us here: Check out our blog! Zero Xcuses Facebook Group: https://www.facebook.com/groups/ZeroXcuses/ Support this show by visiting the Zero Xcuses RECOMMENDED BOOKS AND PRODUCTS Amazon Page

The search for Barovia begins. Translation: The hunt for the oldest person available begins. Results: No old people were found, but Enna wandered off to a mysterious camp with strange people. What do these strange people want? Do these idiots truly know what trouble they got themselves into?

We are six nights away from a stacked WWE No Mercy card, but WWE Raw set the table! Sean Ross Sapp and Alex Pawlowski are here to talk all the news! Topics include - WWE Raw! - No Mercy predictions! - Bobby "The Brain" Heenan - SRS talks Billy Robinson - Paige return?

Robert Gerlach, a global expert on organizational creativity, has taught companies such as Microsoft, Samsung and BASF the fine art of inspiring creativity. Based in Stuttgart, Germany, Robert’s company – iQudo, recently conducted a landmark survey in the U.S. to discover the secret ingredients of company-wide creativity. The results were not what anyone expected. This week on Monday Morning Radio with reputation coach and host Dean Rotbart, Robert offers some of his best tips on how to inspire your business to be more creative. Photo: Robert Gerlach, iQudoPosted: January 18, 2016Monday Morning Run Time: 31 minutes 39 seconds Dean Rotbart will next present his popular Reputation Tool Chest Workshop at Wizard Academy on February 16th and 17th. Let Dean teach you to how to build an unparalleled online reputation for you or your business. Registration is limited, so don't delay.

The world is shocked, and many disappointed, that Israeli Prime Minister Benjamin Netanyahu has been re-elected despite attempts to discredit him in the media. Israel is moving away from a two state solution a viable reality, ensuring Jerusalem remains the undivided capital, and Judea and Samaria are settled with God's people, in accordance with the word of God.

The world is shocked, and many disappointed, that Israeli Prime Minister Benjamin Netanyahu has been re-elected despite attempts to discredit him in the media. Israel is moving away from a two state solution a viable reality, ensuring Jerusalem remains the undivided capital, and Judea and Samaria are settled with God's people, in accordance with the word of God.

Purpose: The purpose of this study was the intraindividual comparison of a 1.0 M and two 0.5 M gadolinium-based contrast agents (GBCA) using equimolar dosing in dynamic and static magnetic resonance angiography (MRA) of the supra-aortic vessels. Materials and Methods: In this institutional review board-approved study, a total of 20 healthy volunteers (mean +/- SD age, 29 +/- 6 years) underwent 3 consecutive supra-aortic MRA examinations on a 3.0 T magnetic resonance system. The order of GBCA (Gadobutrol, Gadobenate dimeglumine, and Gadoterate meglumine) was randomized with a minimum interval of 48 hours between the examinations. Before each examination and 45 minutes after each examination, circulatory parameters were recorded. Total GBCA dose per MRA examination was 0.1 mmol/kg with a 0.03 mmol/kg and 0.07 mmol/kg split for dynamic and static MRA, respectively, injected at a rate of 2 mL/s. Two blinded readers qualitatively assessed static MRA data sets independently using pairwise rankings (superior, inferior, and equal). In addition, quantitative analysis was performed with signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) evaluation as well as vessel sharpness analysis of static MRA using an in-house-developed semiautomated tool. Dynamic MRA was evaluated for maximal SNR. Statistical analysis was performed using the Cohen kappa, the Wilcoxon rank sum tests, and mixed effects models. Results: No significant differences of hemodynamic parameters were observed. In static MRA, Gadobutrol was rated superior to Gadoterate meglumine (P < 0.05) and equal to Gadobenate dimeglumine (P = 0.06) with good to excellent reader agreement (kappa, 0.66-0.83). In static MRA, SNR was significantly higher using 1.0 M Gadobutrol as compared with either 0.5 M agent (P < 0.05 and P < 0.05) and CNR was significantly higher as compared with Gadoterate meglumine (P < 0.05), whereas CNR values of Gadobutrol data sets were not significantly different as compared with Gadobenate dimeglumine (P = 0.13). Differences in CNR between Gadobenate dimeglumine and Gadoterate meglumine were not significant (P = 0.78). Differences in vessel sharpness between the different GBCAs were also not significant (P > 0.05). Maximal SNR in dynamic MRA using Gadobutrol was significantly higher than both comparators at the level of the proximal and distal internal carotid artery (P < 0.05 and P < 0.05; P < 0.05 and P < 0.05). Conclusions: At equimolar doses, 1.0 M Gadobutrol demonstrates higher SNR/CNR than do Gadobenate dimeglumine and Gadoterate meglumine, with superior image quality as compared with Gadoterate meglumine for dynamic and static carotid MRA. Despite the shortened bolus with Gadobutrol, no blurring of vessel edges was observed.

Aims: Transesophageal echocardiography (TEE) is the gold standard for the detection of thrombi in patients with atrial fibrillation (AF) before undergoing early electrical cardioversion (CV). However, TEE generates inconclusive results in a considerable number of patients. This study investigated the influence of contrast enhancement on interpretability of TEE for the detection of left atrial (LA) thrombi compared to conventional TEE and assessed, whether there are differences in the rate of thromboembolic events after electrical cardioversion. Methods: Of 180 patients with AF (51 females, 65.2 +/- 13 years) who were referred to CV, 90 were examined with native imaging and contrast enhancement within the same examination (group 1), and 90 were examined with native TEE alone and served as control (group 2). Cineloops of the multiplane examination of the LA and LA appendage (LAA) were stored digitally before and, in group 1, after intravenous bolus application of a transpulmonary contrast agent. Images of group 1 were assessed offline and the diagnosis of LA thrombi was made semi-quantitatively: 1= thrombus present; 2=inconclusive result; 3=no thrombus. The presence of spontaneous echocontrast (SEC) was registered and flow velocity in the LA appendage (LAA-flow) was measured. All patients in whom CV was performed were followed up for 1 year or until relapse of AF. CV related adverse events were defined as any thromboembolic event within 1 week after CV. Results: No serious adverse events occurred during TEE and contrast enhanced imaging. In group 1 atrial thrombi were diagnosed in 14 (15.6%) during native and in 10 (11.1%) patients during contrast enhanced imaging (p

Background: Climacteric increases the risk of thrombotic events by alteration of plasmatic coagulation. Up to now, less is known about changes in platelet-(PMP) and endothelial cell-derived microparticles (EMP). Methods: In this prospective study, plasma levels of microparticles (MP) were compared in 21 premenopausal and 19 postmenopausal women. Results: No altered numbers of total MP or EMP were measured within the study groups. However, the plasma values of CD61-exposing MP from platelets/megakaryocytes were higher in premenopausal women (5,364 x 10(6)/l, range 4,384-17,167) as compared to postmenopausal women (3,808 x 10(6)/l, range 2,009-8,850; p = 0.020). This differentiation was also significant for the subgroup of premenopausal women without hormonal contraceptives (5,364 x 10(6)/l, range 4,223-15,916; p = 0.047; n = 15). Furthermore, in premenopausal women, higher plasma levels of PMP exposing CD62P were also present as compared to postmenopausal women (288 x 10(6)/l, range 139-462, vs. 121 x 10(6)/l, range 74-284; p = 0.024). This difference was also true for CD63+ PMP levels (281 x 10(6)/l, range 182-551, vs. 137 x 10(6)/l, range 64-432; p = 0.015). Conclusion: Climacteric lowers the level of PMP but has no impact on the number of EMP in women. These data suggest that PMP and EMP do not play a significant role in enhancing the risk of thrombotic events in healthy, postmenopausal women. Copyright (C) 2012 S. Karger AG, Basel

Background: Sentinel lymph node biopsy (SLNB) has become the standard care for melanoma and is an important diagnostic procedure. It has been doubted whether lymphoscintigraphy detects the correct sentinel lymph node (SLN) when excision of the tumor and SLNB are not performed at the same time. This would imply that this sequential approach may have an increased risk of undetected micrometastases resulting in a worse outcome. Objective: The purpose of the present study was to compare the outcome of melanoma patients having received excision of the tumor and SLNB either at the same time or consecutively. Methods: A total of 854 patients with cutaneous melanoma were enrolled in this retrospective study between September 1996 and November 2007. Disease-free (DFS) and overall survivals (OS) were estimated using the Kaplan-Meier product limit method and were analyzed by the log rank test. Results: No statistically significant difference was found regarding DFS, progression rates and OS in patients with primary tumor excision and SLNB at the same time compared with patients with excisional biopsy of primary tumor and SLNB at different times. Conclusion: These data suggest that excisional biopsy of the primary tumor does not prevent the correct SLN mapping in melanoma patients. Copyright (C) 2010 S. Karger AG, Basel

Background: Three genes have been confirmed as major joint susceptibility genes for endocrine autoimmune disease: human leukocyte antigen class II, cytotoxic T-lymphocyte antigen 4 and protein tyrosine phosphatase non-receptor type 22. Recent studies showed that a genetic variation within the interferon induced helicase domain 1 (IFIH1) locus (rs1990760 polymorphism) is an additional risk factor in type 1 diabetes and Graves' disease (GD). Methods: The aim of the present study was to investigate the role of the rs1990760 polymorphism within the IFIH1 gene in German patients with GD (n = 258), Hashimoto's thyroiditis (HT, n = 106), Addison's disease (AD, n = 195) and healthy controls (HC, n = 227) as well as in 55 GD families (165 individuals, German) and 100 HT families (300 individuals, Italian). Furthermore, the interaction between rs1990760 polymorphism with human leukocyte antigen (HLA) risk haplotype DQ2(DQA*0501-DQB*0201), the risk haplotypes DQ2/DQ8 (DQA*0301-DQB*0302) and the status of thyroglobulin antibody (TgAb), thyroid peroxidase antibody (TPOAb) and TSH receptor antibody (TRAb) in patients and families were analysed. Results: No significant differences were found between the allele and genotype frequencies for rs1990760 IFIH1 polymorphism in patients with GD, HT, AD and HC. Also no differences were observed when stratifying the IFIH1 rs1990760 polymorphism for gender, presence or absence of thyroid antibodies (GD: TRAb and HT:TPOAb/TgAb) and HLA risk haplotypes (DQ2: for GD and HT, DQ2/DQ8: for AD). Furthermore the transmission analysis in GD and HT families revealed no differences in alleles transmission for rs1990760 IFIH1 from parents with or without HLA risk haplotype DQ2 to the affected offspring. In contrast, by dividing the HT parents according to the presence or absence of thyroid Ab titers, mothers and fathers both positive for TPOAb/TgAb overtransmitted the allele A of IFIH1 rs1990760 to their HT affected offspring (61.8% vs 38.2%; p = 0.05; corrected p [pc] = 0.1). However, these associations did not remain statistically significant after correction of the p-values. Conclusion: In conclusion, our data suggest, no contribution from IFIH1 rs1990760 polymorphism to the pathogenesis of either Graves' disease, Hashimoto's thyroiditis or Addison's disease in our study populations. However, in order to exclude a possible influence of the studied polymorphism in specified subgroups within patients with autoimmune thyroid disease, further investigations in larger populations are needed.

Background/Aims: To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining properties in humans.Methods: BBG was injected into the 11 rat eyes to evaluate toxic effects with balanced salt solution (BSS) serving as control. Retinal toxicity was assessed by retinal ganglion cell (RGC) counts and by light microscopy 7 days later. In addition, BBG was applied during vitrectomy for macular hole (MH) (n = 15) or epiretinal membranes (ERM) (n = 3) in a prospective, non-comparative consecutive series of patients. Before and after surgery, all patients underwent a complete clinical examination including measurement of best corrected visual acuity (VA) and intraocular pressure, perimetry, fundus photography and optical coherence tomography. Patients were seen 1 day before surgery and then in approximately four weeks intervals.Results: No significant reduction in RGC numbers and no morphological alterations were noted. A sufficient staining of the internal limiting membrane (ILM) was seen in patients with MH, while the staining pattern in ERM cases was patchy, indicating that parts of the ILM were peeled off along with the ERM in a variable extent. All MHs could be closed successfully. VA improved in 10 eyes (56%; 8/15 MH patients, 2/3 ERM patients), was unchanged in four eyes (22%; all MH patients) and was reduced in four eyes (22%; 3/15 MH, 1/3 ERM). No toxic effects attributable to the dye were noted during patient follow-up. The ultrastructure of tissue harvested during surgery was unremarkable.Conclusion: Brilliant Blue provides a sufficient and selective staining of the ILM. No retinal toxicity or adverse effects related to the dye were observed in animal and human studies. The long-term safety of this novel dye will have to be evaluated in larger patient series and a longer follow-up.

Background: ADAM33, the first asthma candidate gene identified by positional cloning, may be associated with childhood asthma, lung function decline and bronchial hyperresponsiveness. However, replication results have been inconclusive in smaller previous study populations probably due to inconsistencies in asthma phenotypes or yet unknown environmental influences. Thus, we tried to further elucidate the role of ADAM33 polymorphisms ( SNPs) in a genetic analysis of German case control and longitudinal populations. Methods: Using MALDI-TOF, ten ADAM33 SNPs were genotyped in 1,872 children from the International Study of Asthma and Allergy in Childhood (ISAAC II) in a case control setting and further 824 children from the longitudinal cohort Multicentre Study of Allergy (MAS). In both populations the effects of single SNPs and haplotypes were studied and a gene environment analysis with passive smoke exposure was performed using SAS/ Genetics. Results: No single SNP showed a significant association with doctor's diagnosis of asthma. A trend for somewhat more profound effects of ADAM33 SNPs was observed in individuals with asthma and BHR. Haplotype analyses suggested a minor effect of the ADAM33 haplotype H4 on asthma ( p = 0.033) but not on BHR. Associations with non atopic asthma and baseline lung function were identified but no interaction with passive smoke exposure could be detected. Conclusion: The originally reported association between ADAM33 polymorphisms and asthma and BHR could not be confirmed. However, our data may suggest a complex role of ADAM33 polymorphisms in asthma ethiology, especially in non atopic asthma.

Background: Photofrin II has been demonstrated to serve as a specific and selective radiosensitizing agent in in vitro and in vivo tumor models. We aimed to investigate the feasibility of a clinical application of Photofrin II. Material and Methods: 12 patients were included in the study (7 unresectable solid tumors of the pelvic region, 3 malignant gliomas, 1 recurrent oropharyngeal cancer, 1 recurrent adenocarcinoma of the sphenoid sinus). The dose of ionizing irradiation was 30-50.4 Gy; a boost irradiation of 14 Gy was added for the pelvic region. All patients were intravenously injected with 1 mg/kg Photofrin II 24 h prior to the commencement of radiotherapy. Magnetic resonance imaging (MRI) controls and in some cases positron emission tomography (PET) were performed in short intervals. The mean follow-up was 12.9 months. Results: No major adverse events were noted. Minor adverse events consisted of mild diarrhea, nausea and skin reactions. A complete remission was observed in 4/12 patients. A reduction in local tumor volume of > 45% was achieved in 4/12 patients. Stable disease was observed in 4/12 patients. 1 patient showed local disease progression after 5 months. Conclusion: The early follow-up results are encouraging regarding the feasibility of the application of Photofrin II as a radiosensitizing agent.

Background: Safe, effective and affordable drug combinations against falciparum malaria are urgently needed for the poor populations in malaria endemic countries. Methylene blue (MB) combined with chloroquine (CQ) has been considered as one promising new regimen. Objectives: The primary objective of this study was to evaluate the safety of CQ-MB in African children with uncomplicated falciparum malaria. Secondary objectives were to assess the efficacy and the acceptance of CQ-MB in a rural population of West Africa. Methods: In this hospital-based randomized controlled trial, 226 children ( 6 - 59 months) with uncomplicated falciparum malaria were treated in Burkina Faso. The children were 4: 1 randomized to CQ-MB (n = 181; 25 mg/kg CQ and 12 mg/kg MB over three days) or CQ ( n = 45; 25 mg/kg over three days) respectively. The primary outcome was the incidence of severe haemolysis or other serious adverse events (SAEs). Efficacy outcomes were defined according to the WHO 2003 classification system. Patients were hospitalized for four days and followed up until day 14. Results: No differences in the incidence of SAEs and other adverse events were observed between children treated with CQ-MB ( including 24 cases of G6PD deficiency) compared to children treated with CQ. There was no case of severe haemolysis and also no significant difference in mean haemoglobin between study groups. Treatment failure rates were 53.7% (95% CI [37.4%; 69.3%]) in the CQ group compared to 44.0% ( 95% CI [36.3%; 51.9%]) in the CQ-MB group. Conclusion: MB is safe for the treatment of uncomplicated falciparum malaria, even in G6PD deficient African children. However, the efficacy of the CQ-MB combination has not been sufficient at the MB dose used in this study. Future studies need to assess the efficacy of MB at higher doses and in combination with appropriate partner drugs.

Objective:The evaluation of the effects of repeated antenatal corticosteriod (CS) medication on birth size and size at the age of 4 years. Methods: 82 children exposed to CS initially between 26 and 28 weeks of gestation were matched with 82 controls of the same gestational age and sex. Results: No differences were observed between the CS and control groups with regard to weight, head circumference, and length at birth and at the age of 4 years. Conclusions: Our study failed to demonstrate that repetitive antenatal medication with CS in order to induce lung maturation has a negative im pact on intrauterine growth and growth in early childhood. Copyright (C) 2001 S. Karger AG, Basel.

Background: Workers on dredgers and lighters on rivers are exposed to the inhalation of aerosols and dusts. Objective: The aim of this study was to investigate effects of river silt aerosol and dust exposure on the respiratory health of dredging employees. Methods: Six era mi nations were performed over a period of 2 years at 4-monthly intervals in 54 seamen with higher silt aerosol exposure and 36 controls of the same employer. Results: No significant differences could be observed between the groups at any time of the study but there was an unexpected significant decrease in the age-corrected expiratory vital capacity (FVC), forced expiratory volume in 1 s (FEV1) and midexpiratory flow rate (MMEF25/75) over the six series in both groups. This may indicate a loss of effort of the participants in re-examinations since biological and technical influences were highly unlikely to be the cause of these findings. Conclusions: Ignoring this possible decline of effort in frequently repeated measurements may result in overestimating potential effects of occupational exposure. Copyright (C) 2000 S. Karger AG, Basel.