Live Well Be Well

Watch the FULL podcast here: https://youtu.be/bj0-zUDFkxcWorried that your HRV looks “low” on your wearable? I ask what a low HRV actually means, why different devices produce different numbers, and when a change is worth paying attention to.This clip explores how to interpret heart rate variability without getting lost in the daily noise. We discuss why HRV is a legitimate health metric with decades of research behind it, yet the absolute score is not comparable across devices or people because different technologies use different calculations. I'm taking a closer look at establishing a personal baseline over 21–30 days, why a four-day rolling view can reduce anxiety, and why consistent shifts over seven or more days matter more than one-off dips. We cover the role of genetics (around 20 percent of HRV), how lifestyle often explains age-related changes, and sex differences including a dip in the 40–50 window likely linked to menopause that later rebounds in the dataset referenced. You'll also hear why stability can reflect resilience, why big swings can be a red flag even when the number is “high,” and how resting heart rate and overnight respiratory rate fit into the bigger picture. I share my own readings (HRV around 10–13 on one device, resting heart rate at 45) and experiences using No Watch, Oura, and Eight Sleep, plus a mention of devices commonly used for HRV. As a nutritionist and health communicator, I focus on practical takeaways: use one device consistently, track trends, and avoid cross-device comparisons.***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/***Let's be friends!

Watch the FULL podcast here: https://youtu.be/Lw6iZbZBiw8Thinking about TRT for low testosterone? This clip takes a closer look at who genuinely benefits from testosterone replacement therapy, what current evidence suggests about safety, and why fertility planning is crucial.I'm exploring with my guest how to distinguish primary from secondary hypogonadism, why symptoms plus true biochemical low testosterone are needed for a diagnosis, and the point that if total testosterone is above 12, TRT isn't indicated. This discussion focuses on updated data around prostate and cardiovascular risk, key contraindications such as active prostate cancer, polycythemia, and heart failure, and the reality that exogenous testosterone suppresses FSH and sperm production, acting like a male contraceptive and not always fully reversible. We also cover off-label options like clomiphene and hCG to support endogenous testosterone when fertility is a priority, the importance of screening for metabolic issues like dyslipidemia and prediabetes, lifestyle considerations, and the social pressures that drive recreational use. There's a brief reflection on age-related declines, the idea that testosterone may drop after men have children, and how broader environmental factors might fit into the picture.As a nutritionist and health communicator, I aim to connect the science with practical, balanced advice so you can discuss options confidently with your clinician.***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/***Let's be friends!

You've been told your phone is just a tool. But what if it's quietly rewiring your motivation, eroding your focus, and crowding out the single chemical your brain craves most - connection?This week on Live Well Be Well, neuroscientist and author TJ Power joins me to explore the science of dopamine, focus, and digital balance. TJ, who developed the DOSE model - dopamine, oxytocin, serotonin, endorphins - reveals how our screen habits are reshaping the brain's chemistry and stealing the satisfaction we once got from real connection.Drawing on his research in neuroscience and mental wellbeing, TJ explains how constant notifications, multitasking, and morning scrolling deplete dopamine, dull our motivation, and even affect emotional regulation. We discuss how to retrain your attention, protect your mornings, and strengthen the part of your brain responsible for self-control and flow.Here's what we dive into:The real data on phone addiction: how an average of 5.5 hours a day and 175 pickups rewires your dopamine system, and why under 3 hours supports better focus and happiness.Dopamine vs. Oxytocin - the neuroscience behind loneliness in the digital age, and how conversation and physical presence can restore deep fulfilment.Serotonin and sleep - how screen time late at night blocks natural serotonin cycles, sunlight absorption, and mood regulation.What is “brain rot”? TJ explains the neuroscience of effortless dopamine, gray matter changes, and why too much stimulation can damage attention networks.ADHD, attention, and environment - how our hunter-gatherer brains are struggling in a high-dopamine world, and what to do about it.AMCC (anterior mid-cingulate cortex) - your brain's “willpower muscle.” Learn how small acts of resistance build real discipline and creativity.Morning habits for dopamine balance - why checking your phone first thing drains focus, and how “computer before phone” rewires productivity.Practical digital boundaries - from the app TJ uses to track pickups (aiming for 50 a day) to phone-free meals that boost oxytocin and presence.Love,Sarah Ann

Watch the FULL podcast here: https://youtu.be/C--vYFyHAEwWhat if your PMS symptoms aren't just about hormones? In this episode, we dive into the cultural, biological, and emotional influences that shape your period experience - from why girls often grow up ashamed of their first cycle to how partners can play a powerful role in reducing PMS stress. You'll learn what a “normal” period really looks like, the green flags that indicate a healthy cycle, and the red flags that may signal something more serious. We also cover practical solutions for painful periods, from heat therapy and yoga to gentle movement that actually helps reduce inflammation. Whether you're struggling with cramps, irregular cycles, or simply want to feel empowered in understanding your body, this conversation offers knowledge every woman should have.Hazel WallaceListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠Watch the full episode on YouTube⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Watch the FULL podcast here: https://youtu.be/XXwgXDeOYJINot sure where to start with your health? The most effective first step, as I discuss here, is to identify the single habit acting as your biggest performance anchor and remove that brake before adding more tips and hacks. This clip explores the “brake vs accelerator” approach to health, why a singular focus outperforms scattered efforts, and how to choose the one area that's genuinely holding you back.As a nutritionist and health communicator, I'm exploring with my guest how to pinpoint your biggest thorn in the side - whether that's body composition, mental health, sleep, eating practices, or even micronutrient habits - and make that your priority. We discuss coaching insights from elite athletes and everyday people, the value of setting six-week, six-month, yearly and decade-long goals, and when it makes sense to overhaul lifestyle as one action-focused goal rather than chasing outcomes. The conversation also touches on immediate vs delayed gratification and why removing anchors reduces wear and tear before you ever need the accelerator.Dr. Andy GalpinListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

This week's guest, Mo Gawdat, former Google [X] Chief Business Officer and author of Solve for Happy, returns with a world-first: EMMA, an AI designed to help humans find and nurture true love. Why? Because loneliness is now epidemic, love has been commercialised, and so many of us feel burnt out by dating. EMMA aims to change the economics of love by deeply getting to know you, matching on values and compatibility (not just looks), and then coaching the relationship that follows. It's about repairing the system and reminding AI what makes humanity worth protecting: our capacity to love.Together we explore:The real crisis in modern love: short relationships, high divorce, and “dating fatigue,” plus Mo's stark maths on why ~95% of romantic encounters now end in breakup.EMMA's purpose: an AI that explicitly refuses to be your “AI girlfriend/boyfriend,” and instead helps you fall in love with another human - while learning, at scale, how humans love.How EMMA works: a gentle onboarding (seven questions, one short video intro), minimal photos to avoid the “meat market,” and a best-friend style of matching and follow-up.Matching for depth, not dopamine: EMMA narrows 30,000 swipes to a handful of highly compatible options - turning each date into an enjoyable, insight-rich experiment.The Empathy Observer: coaching you to consider the other person's experience and strengthen the “you-with-you” relationship first - the foundation for any love that lasts.Why India's relationship outcomes look so different from the West, and how expectations shape love.Expert Modes (including GRACE): support for conscious breakups, co-parenting, and even money - one of the top reasons couples split.Mo's own lessons in vulnerability, presence, and what it means to truly “show up.”Love,Sarah Ann

Watch the FULL podcast here: https://youtu.be/AySFUeR1pw8Are NAD+ drips or NMN supplements a smart way to support longevity? I connect what NAD+ actually is with what current human studies show and why dosage, delivery and safety still have big question marks.This clip takes a closer look at what NAD+ (nicotinamide adenine dinucleotide) does in cellular energy, why interest has grown around aging, and how much of the hype is based on animal data rather than robust human trials. I'm exploring with my guest the difference between oral supplements and IV drips, including why IV bypasses digestion but still may not deliver NAD+ where it's needed inside cells, and the fact that effective dosing schedules are unknown. We discuss reported side effects from IV drips like flushing and rapid heart rate, the theoretical concern that excessive NAD+ could support cancer cell proliferation in certain contexts, and how high-dose single nutrients can disrupt balance when nutrients normally work in synergy. As a nutritionist and health communicator, I weigh the evidence against the costs and risks, and point to practical options with stronger support for mitochondrial health: exercise such as HIIT and zone 2 training, possibly cold exposure, investing in mental health, and dietary precursors from foods like green vegetables, fish, mushrooms and edamame.Dr Rupy Aujla in conversation with Sarah Ann Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Watch the FULL video here: https://youtu.be/hsaGZXiEbNsMost women don't realize how much their hormones shape their metabolism and recovery or how wearables often get it wrong. In this clip, Dr. Stacy Sims breaks down what really happens to your insulin sensitivity and immune system throughout your cycle, why progesterone makes you temporarily more insulin resistant, and why that's completely normal.She also exposes how continuous glucose monitors and fitness trackers often mislead women built on male-based data, their algorithms can cause unnecessary stress and confusion.Dr. Stacy SimsListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

From growing up on food stamps to becoming one of the youngest full professors in the US, Dr. Andy Galpin's story is nothing short of extraordinary. A world-leading human performance scientist, Andy shares the values of hard work and ambition instilled by his parents and how those principles carried him from adversity to academic success.But this isn't just a story of resilience. Andy takes us deep into the science of human performance – from understanding what truly anchors your progress, to why consistent habits matter more than hacks, and how sleep remains the most powerful (and overlooked) tool we have for health and longevity.Together we explore:The importance of addressing ‘performance anchors' before chasing optimisationNervous system health, stress load, and what HRV really tells usCold plunges, saunas, and whether they actually improve resilienceHydrogen water: hype or help?Why sleep is the cornerstone of health, and the environmental factors that shape itPractical strategies to improve recovery, energy, and performanceThis conversation is both deeply human and highly practical - inspiring you to re-think how you approach your health, performance, and success.Love,Sarah Ann

Inflammation isn't always the enemy, it's your body's defense system. But when it gets out of control, it can silently drive arthritis, heart disease, gut issues, and even mental health struggles. In this episode, we break down what the Dietary Inflammatory Index (DII) actually shows, why plant protein and fiber lower inflammation, and how animal protein may raise it.Discover the foods with the strongest anti-inflammatory effects from herbs and spices like turmeric and oregano, to olive oil, nuts, seeds, oily fish, berries, and polyphenol-rich vegetables. Learn why balance is key, and how simple daily habits (movement, stress management, sleep) impact your inflammation levels just as much as diet.We also unpack why the Mediterranean diet remains one of the best-studied anti-inflammatory eating patterns worldwide.Rupy AujlaListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***If you enjoyed this episode you might also like:How to Increase Protein in Your Diet and Why It Matters for Longevity & Hormone Health | Dr Rupyhttps://youtu.be/AySFUeR1pw8***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Are your supplements actually helping you, or just draining your wallet? In this episode, Dr. Stacy Sims breaks down the truth about three of the most popular supplements women buy: collagen, magnesium, and creatine.You'll learn which type of collagen (if any) really supports joint health, why most collagen powders don't count toward your daily protein, and the surprising reason women should be cautious with “vegan collagen.” Dr. Sims also explains which form of magnesium actually improves sleep and muscle relaxation — and why so many products don't deliver results. Finally, she reveals why creatine is one of the most powerful yet overlooked supplements for women, especially in perimenopause, supporting energy, mood, gut health, and performance.Dr. Stacy SimsListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***If you enjoyed this episode you might also like:Dr. Stacy Sims EXPOSES the Myths Hurting Women's Health | Fasting, Protein & Exercisehttps://www.youtube.com/watch?v=E1uksGzoick***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Most conversations about fertility focus on women. But here's the truth: up to 50% of infertility cases are male and men's reproductive health is a powerful window into their overall wellbeing, longevity, and disease risk.This week's guest, Professor Suks Minhas, world-leading consultant urologist and expert in male fertility is here to change how we think about men's health. With decades of clinical and research expertise, he reveals why sperm counts are falling, what it really says about men's health today, and the practical steps every man can take to protect his future.Together we explore: – Why male infertility makes up half of cases and why it's rarely discussed – The surprising links between sperm health, testosterone, and metabolic disease – DNA fragmentation: the overlooked cause of “unexplained infertility” – How lifestyle, stress, alcohol, and obesity directly affect fertility– The role of endocrine disruptors and environmental toxins in declining sperm quality – Fertility preservation: should men also consider freezing their sperm? – Testosterone replacement therapy (TRT): who it helps, who it harms, and why it can act as a male contraceptive – Actionable, evidence-based ways to optimise male fertility and long-term healthThis isn't just a conversation about reproduction. It's a wake-up call for men's health, fertility, and longevity. Whether you're thinking about children, or simply want to future-proof your health, this episode gives you the clarity to take action.Love,Sarah Ann

Can your menstrual cycle really change how you train, recover, and build strength - or is that just fitness hype? In this clip, we dive deep into the latest research on exercise and the menstrual cycle. While some studies suggest a small dip in performance during your period and more strength potential around ovulation, the evidence is mixed and often misunderstood. The real takeaway? Every woman's body responds differently. This conversation explores how athletes and everyday women can use cycle awareness as a guide - not a strict rulebook - when it comes to training, recovery, and performance. Whether you're running marathons, lifting weights, or fitting workouts around work and family, this discussion will help you understand what's fact, what's myth, and how to tune into your own body.Hazel WallaceListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:What Men AND Women Must Know About Women's Hormones, Periods & Fertility | Dr Hazel Wallacehttps://youtu.be/C--vYFyHAEw***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

How much protein do you actually need per day? In this clip, we break down the science of protein requirements by body weight and show what that looks like in real food examples. From Greek yogurt and nuts to tempeh and chicken, here's a practical, evidence-based guide to daily protein intake.Rupy AujlaListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:How Much Protein Do You Really Need for Longevity? | Evidence-Based Guide with Dr. Rupy Aujlahttps://www.youtube.com/watch?v=AySFUeR1pw8***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

You've been taught to think of your period as just that - a period. A monthly inconvenience to be managed with tampons and painkillers.But what if your menstrual cycle is actually a vital sign? A powerful, daily indicator of your brain, gut, and metabolic health that you've been taught to ignore?This week's guest, Dr. Hazel Wallace - medical doctor, nutritionist, and author of Not Just a Period is here to dismantle the myths that keep women in the dark about their own bodies. Drawing from her own frustrating journey to a PCOS diagnosis, she reveals why so much of what we're told about our hormones is wrong, and how understanding your cycle is the key to unlocking better health, energy, and performance.Together we explore:- Why your cycle is so much more than just fertility- The hidden ways hormones impact your mood, sleep, cravings, and even your gut- Why dismissive advice like “lose weight” or “cut carbs” is failing millions of women- The truth about training and your cycle: when to push, when to rest, and how to listen to your body- Amenorrhea: the real reasons you might lose your period (it's not just stress)- How to advocate for yourself in a medical system that too often dismisses women's pain- Practical, evidence-based tools to support your hormones with nutrition and lifestyleThis isn't just a conversation about periods. It's a roadmap to hormonal literacy and self-advocacy. If you've ever felt confused, dismissed, or powerless over your own body, this episode will give you the clarity and confidence to finally take back control.Love,Sarah Ann

Cordyceps mushrooms have been used for centuries, but what does modern science reveal about their effects on energy, oxygen uptake, and fertility? In this clip, we explore the evidence, separating tradition from data to uncover whether cordyceps can truly enhance vitality.Dr. Catalina Fernández Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:Can These Mushrooms Heal Your Gut, Stop Alzheimer's, & Fight Cancer? | Dr Catalina Fernándezhttps://www.youtube.com/watch?v=FM44DD_Cc78***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Bleeding gums might be more than a dental issue. they could signal hidden risks for Alzheimer's, heart disease, and even cancer. In this episode, we unpack how the oral microbiome drives inflammation, plaque buildup, and systemic disease. Could flossing actually add years to your life?Dr. Katie LeeListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:The No.1 Oral Microbiome Expert: How Your Mouth Could Be Causing Infertility! | Dr. Katie Leehttps://www.youtube.com/watch?v=J3BCy4e5co4***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Protein is at the forefront of health and longevity research. But how much do you really need? And is it just about muscles, or does protein hold the key to aging well, preventing frailty, and protecting long-term health?This week's guest, Dr. Rupy Aujla, NHS GP, nutritional medicine expert, and founder of Doctor's Kitchen, takes us inside the science of protein, inflammation, and longevity. From his own story of reversing atrial fibrillation through lifestyle change, to the cutting-edge research that's shifting how we think about diet and healthspan, Rupy brings both expertise and lived experience.Together we explore: – How much protein you really need: why the old 0.8 g/kg guideline is outdated and what to aim for now – Protein timing: how protein distribution impacts muscle, bone, and immune health – Women, fertility & menopause: how aging changes protein needs and why women may benefit from more – Beans, lentils, and plants: why plant proteins are powerful but not always enough – Anti-inflammatory eating: what the Dietary Inflammatory Index reveals – Silent killers of aging: how falls and frailty shorten lifespan even more than many chronic diseases – Longevity fads vs facts: NAD drips, supplements, and what really works – Practical eating: a simple framework to build plates high in protein and flavorLove,Sarah Ann

Learn about 12 powerful spices that help balance inflammation and support a strong immune system. In this conversation with Kanchan Koya, you'll discover why chili lovers might live longer, and simple ways to add these spices to soups, teas, and everyday meals for better health.Dr. Kanchan KoyaListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:Surprising Spice Benefits that HELP FIGHT Chronic Disease and Diabeteshttps://www.youtube.com/watch?v=hi0zgZ61Op0***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Is your mouthwash, toothpaste, or morning routine actually harming your oral health? In this conversation with Katie Lee, we explore the surprising truth about swishing water vs. mouthwash, the hidden risks of essential oils and oil pulling, and the heated debate on fluoride in toothpaste and tap water. Dr. Katie LeeListen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:The No.1 Oral Microbiome Expert: How Your Mouth Could Be Causing Infertility! | Dr. Katie Leehttps://www.youtube.com/watch?v=J3BCy4e5co4***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

We're not taught how to protect our brains.We're not taught how food, sleep, and stress shape memory and mood.We're not taught why dementia is rising or that prevention starts decades earlier.But we should be.This week's Brain Health Masterclass brings together leading neurologists, scientists, and longevity experts to explore what really keeps our minds sharp. From anxiety and PTSD to dementia, menopause, psychedelics, gut-brain connection, and even the oral microbiome, you'll learn why your daily choices matter more than you think.In this conversation, I'm joined by world-leading voices, including:Dr. Lisa Feldman Barrett – neuroscientist redefining how emotions shape the brainDr. William Li – physician-scientist on food as medicine and brain regenerationDan Buettner – founder of the Blue Zones uncovering the world's longest-lived communitiesDr. Sarah McKay – neuroscientist bringing clarity to women's brain healthDr. Chris Palmer – psychiatrist linking nutrition, metabolism, and mental healthDr. Rick Doblin – pioneer in psychedelic research for trauma and healingDr. Katie Lee – oral microbiome researcher revealing surprising links to dementiaDrs. Ayesha & Dean Sherzai – neurologists on preventing Alzheimer's with lifestyleTogether we explore:- The Brain's #1 Job (It's Not What You Think)- How gut health, diet, and even flossing impact dementia risk- What Blue Zones teach us about friendship, purpose, and longevity- The myths of menopause brain fog, and the resilience science reveals- Can psychedelics safely rewire trauma circuits?- Daily habits that protect memory, mood, and cognitionLove,Sarah Ann

Do you really have a food allergy or is it just an intolerance? In this conversation with Will Bulsiewicz, you'll learn the crucial difference between food allergies, FODMAP intolerances, and histamine sensitivity, and why misdiagnosing yourself can lead to unnecessary restrictions and fear.Dr. Wil BulsiewiczListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:No.1 Gut Scientist: Insane Fiber Benefits to HEAL YOUR GUT & Beat Disease | Dr Will Bulsiewiczhttps://www.youtube.com/watch?v=8X3b4Hzq75k***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Is zone 2 training actually effective for women? In this conversation with Dr. Stacy Sims, she breaks down the science behind Zone 2 and explains why women may need to rethink how they train for fitness and longevity.Dr. Stacy SimsListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:Dr. Stacy Sims EXPOSES the Myths Hurting Women's Health | Fasting, Protein & Exercise https://www.youtube.com/watch?v=E1uksGzoick***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Plastics aren't just polluting the planet. They're showing up in our bodies in ways we never imagined. From our brain to our bloodstream, even fertility treatments, microplastics are everywhere.This week's guest, Dr. Robin Mesnage, toxicologist and researcher, reveals why microplastics and pesticides are far more pervasive than we realize, from our kitchen cupboards to our hospitals. Drawing on cutting-edge research, he explains how plastics interact with our hormones, fertility, and long-term health, while also giving empowering, practical steps to reduce exposure without fear or overwhelm.Together we explore: – How microplastics end up in our brain, heart, and reproductive organs – Why BPA-free labels often don't mean “safe” – The surprising truth about glass vs. plastic bottles – How IV drips and hospital environments expose us to hidden toxins – The fertility crisis: sperm count decline, egg retrieval, and endocrine disruptors – Pesticides, organic vs. non-organic food, and what's really worth paying more for – Practical, realistic swaps in the kitchen, home, and daily life to lower toxic load – Why small, sustainable changes are the most powerful path forwardLove,Sarah Ann

What if your immune system was shaping your personality without you even knowing? In this clip, immunologist Dan Nicolau reveals surprising science behind the mind-body connection, how curiosity and forgiveness affect health, and why infections like toxoplasmosis can radically change behavior.Dan NicolauListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:The Brain Immune Expert: ALERT! Social Media Is Reprogramming Your Immune System | Prof Nicolauhttps://youtu.be/2zNw6pzv8qk***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Can medicinal mushrooms really support cancer treatment? Dr. Catalina Fernández explains how mushrooms may help strengthen the immune system, reshape the gut microbiome, and improve quality of life during conventional cancer care.Dr. Catalina FernándezListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:Can These Mushrooms Heal Your Gut, Stop Alzheimer's, & Fight Cancer? | Dr Catalina Fernándezhttps://youtu.be/FM44DD_Cc78***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

You might think depression looks like sadness, withdrawal, or losing all motivation. But what if it could also look like achievement, productivity, and relentless drive?This week's guest, Dr. Judith Joseph, psychiatrist, researcher, and author of High Functioning Depression, reveals why so many high performers silently struggle with emptiness, anxiety, and disconnection, despite looking like they “have it all.” Drawing from both her clinical expertise and lived experience, Dr. Joseph breaks down why society rewards overwork, how masking with busyness becomes a dangerous coping strategy, and why prevention, not crisis, is the future of mental health. Her work is reshaping how we understand success, resilience, and joy.Together we explore: – The hidden signs of high-functioning depression and why it's so often missed – Why constant productivity can be a coping mechanism for unresolved pain – How anxiety and depression overlap more than we realize – The role of social media, overstimulation, and Gen Z's rising mental health crisis – Why toxic relationships and lack of validation fuel burnout – Dr. Joseph's “5 V's” framework for reclaiming joy and building resilience – How to slow down, self-validate, and truly savor life without losing ambitionThis is not about lowering your standards. It's about rewriting the script on success, one where ambition and well-being can co-exist. If you've ever wondered why achievement alone doesn't make you feel fulfilled, this conversation will give you the clarity and tools to change that.Love,Sarah Ann

Doug Bopst opens up about the hidden costs of chasing perfection in fitness and life. From battling negative self-talk and saying yes to everything, to shifting his health priorities and repairing relationships, Doug shares lessons that go far beyond the gym.Doug BopstListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:From Drug Addiction to Fitness Inspiration - The Conversation That Saved His Life | Doug Bopsthttps://youtu.be/oT0c7BuvVfk***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Artificial sweeteners promise a “sugar-free” solution, but what does the science actually show? In this conversation with Emeran Mayer, we explore their impact on the gut microbiome, metabolism, and long-term health, along with how sugar cravings are formed and whether soda myths hold up. Dr. Emeran MayerListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:The Gut-Mind Doctor: The Mind & Food Strategies That Can Heal Your Gut Microbiome | Dr. Emeran Mayerhttps://youtu.be/yL5ZtoJAUBs***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

You think you know what's stopping you from living a truly fulfilled, meaningful life.You blame lack of time, not enough money, or the constant pressure to do more.But what if the real barrier is how you define wealth and the way society has programmed you to chase success?This week's guest, Robin Sharma, is a globally respected leadership expert, speaker, and bestselling author of The 5AM Club and The Wealth Money Can't Buy. His work has inspired millions worldwide, from billionaires and CEOs to athletes and creatives, to rethink success and build lives that feel truly rich.We explore: – Why “keeping death close” might be the secret to truly living– The 5 daily questions that set you up for gratitude, clarity, and meaning – How to move from chasing applause to cultivating joy, peace, and freedom – The 8 forms of wealth that money can't buy, and how to nurture them daily – Why releasing resentment is essential for creativity, health, and intimacy – Practical tools to overcome self-doubt, unworthiness, and toxic self-talk – The importance of relationships, self-compassion, and learning to savor lifeThis isn't about abandoning ambition. It's about redirecting it toward what actually fulfills you. It's about building a life so rich that when you look back, you know you didn't just exist... you truly lived.Connect with Robin Sharma:

In this heartfelt episode of Five Questions to Nourish the Mind, Body & Soul, Katie Lee opens up about courage, personal growth, and the profound lessons learned through life's biggest challenges. From a six-year journey to motherhood, to the smallest daily changes like honoring her body's need for rest.Dr. Katie LeeListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:The No.1 Oral Microbiome Expert: How Your Mouth Could Be Causing Infertility! | Dr. Katie Leehttps://www.youtube.com/watch?v=J3BCy4e5co4***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Could shifting your eating window radically improve your sleep, energy, and mental clarity? In this clip, we explore the science and personal experience behind eating in a 4–6 hour window, finishing meals by early afternoon. Learn how meal timing affects sleep quality, why hunger before bed can be a good thing, and the fine line between discipline and food restriction.Talmage JohnsonListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠⁠***If you enjoyed this episode you might also like:The 19-Year-Old Trying To Become The Oldest Man Alive: Inside The Blueprint Cult – Talmage Johnsonhttps://www.youtube.com/watch?v=aqO-LIavXxk***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

You think you know what's making you feel exhausted, anxious, or unwell.You blame stress, your hormones, or bad luck.But what if one of the biggest factors is in over half the food you eat and you've been told it's “healthy”?This week's guest, Milli Hill, is an award-winning journalist, speaker, and author whose latest work reveals the hidden role ultra-processed foods play in women's health. From autoimmune disease, depression, and infertility to painful periods, menopause symptoms, and chronic inflammation, her research exposes a truth that's been hiding in plain sight and asks why we've normalised women's suffering for so long.We explore: – Why women face higher rates of autoimmune disease, depression, and the role of ultra-processed food – How UPFs fuel inflammation, disrupt the gut microbiome, and affect long-term health – The marketing tricks behind “healthy” products that keep us hooked – Why reducing UPFs is about reclaiming nourishment, not restriction– Practical swaps that fit into busy lives without overwhelm – The cultural loss of cooking, eating, and connection, and how to bring it backYou deserve answers your doctor might not have given you. This conversation is about taking back control of what nourishes you, asking the questions women's health has ignored for too long, and making changes that support your body, mind, and future one choice at a time.Connect with Milli Hill: Website: https://www.millihill.co.uk/ Instagram: https://www.instagram.com/millihill/ Twitter/X: https://twitter.com/millihill Books: Give Birth Like a Feminist, The Positive Birth Book, My Period

In this 5 Questions episode, we invite Simon Sinek to speak straight from the heart. From overcoming self-doubt to redefining his relationship with sugar, and learning how listening changed everything, each answer offers unexpected wisdom.Listen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠***If you enjoyed this episode you might also like:Simon Sinek: The ADHD Superpower - Why It's My Greatest Advantagehttps://youtu.be/6fnTHiI8oY0***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Struggling with gut health but not sure where to begin? Dr. Emily Leeming shares a practical guide with five easy, evidence-backed changes you can implement right now to support your microbiome, digestion, and even mental clarity. Learn how fiber, fermented foods, polyphenols, dietary diversity, and a simple breathing technique can transform your gut, and your overall health.Dr. Emily LeemingListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠⁠londonnootropics.com⁠⁠⁠⁠***If you enjoyed this episode you might also like:Is Your Partner Wrecking Your Gut Health? And How Fibre Can Heal You | Dr. Emily Leeminghttps://youtu.be/rqwdYiHktjA***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

You think you know what resilience looks like.You picture someone gritting their teeth, pushing through, holding on tight.Someone who climbs mountains without oxygen, survives avalanches, makes it to magazine covers.This week's guest, Cory Richards, did all of that. He isn't just a world-renowned climber and National Geographic photographer, he's someone who has been to the edge, and then even further inward. From becoming the first American to summit an 8,000m peak in winter, to childhood trauma, being institutionalised at 14, homelessness at 15, battling bipolar disorder, addiction, sexual exploration that blurred consent, and suicidal ideation, his story is a mirror to everything we hide, deny, and eventually must face. But what he discovered is that none of that was resilience at all. It was survival.In this unforgettable conversation, Cory opens up about the long descent after the summit, the messy, nonlinear path of healing, identity, and emotional truth. His memoir The Color of Everything isn't just a book. It's a reckoning. And here, with radical honesty, we unravel the questions we rarely give men, or ourselves, permission to ask.We explore: – What surviving an avalanche teaches you about control, surrender, and mortality – How bipolar II and trauma shaped his mind and nearly took his life – Why sex became a substitute for safety, and what real intimacy requires – The complicated truth of masculinity, shame, and public accountability – Why survival isn't the same as resilience and why real resilience starts with letting go– How self-sourced love, community, and curiosity are changing the way he livesLove,Sarah Ann

What if everything you thought about healing was incomplete? In this 5 Questions episode, Dr. Emilia Vuorisalmi shares the lesser-heard truth behind wellness trends, love addiction, emotional burnout, and the power of simply learning how to breathe again. We explore why self-worth, presence, and storytelling may be the most vital tools for health.Dr. Emilia VuorisalmiListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠londonnootropics.com⁠⁠⁠***If you enjoyed this episode you might also like:These 3 Hormones Could Be Why You're Addicted to Love | Dr. Emilia Vuorisalmihttps://youtu.be/tjms17l7hao***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

In this thought-provoking conversation, we explore the deep connection between meaning, wisdom, and growth. From the misunderstanding of meaning in modern culture to the importance of shared wisdom, we dive into how self-deception and trauma shape our lives. Is wisdom something we can cultivate alone? John VervaekeListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠⁠londonnootropics.com⁠⁠⁠***If you enjoyed this episode you might also like:Understanding the Loneliness Epidemic | Dr. John Vervaeke on Trust, Belonging & Meaninghttps://youtu.be/AbxCzAt6ZcM***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Your neurons can become younger.Your gut can reshape itself in five days.Your immune system can learn to fight cancer.This isn't theory. It's mycology.And it's about to change how you think about what your body can do.This week on Live Well Be Well, I sit down with Dr. Catalina Fernández de Ana Portela, a pioneering mycologist and oncologist who's spent 26 years unlocking the therapeutic power of mushrooms. From Lion's Mane and Reishi to Cordyceps, she's led clinical trials across cancer, autism, neurodegenerative disease, and fertility, quietly reshaping how we think about prevention, healing, and the intelligence of nature.In this episode, we explore:The real science behind Lion's Mane: neuroplasticity, contains GABA, and why your neurons can actually become youngerWhy Lion's Mane may support brain health, gut health, autism, Alzheimer's, multiple sclerosis, and Parkinson's treatmentHow Reishi could help reduce stress and anxiety, and modulate neurotransmitters like GABAThe real science behind putting mushrooms in your coffee (yes, it's more than a trend!)What Cordyceps does for energy, fertility, and performance, and how mushrooms support both male and female reproductive healthBreakthrough research on mushrooms in integrative oncology, including their effects on the gut microbiome and immune systemThe gut-brain axis: how mushrooms can reshape your microbiome in 5 days and support conditions from autism to cancerThe supplement quality crisis: why only 25% of products contain what they claim and how to find trustworthy brandsWhether you're curious about adding Lion's Mane to your morning coffee, wondering if Reishi could actually help your anxiety, or want to understand how mushrooms are being used alongside chemotherapy in clinical trials, this conversation will change how you think about what's possible. The question isn't whether mushrooms work. The science is undeniable. Now it's about finding the right approach for you.Love,Sarah Ann

How does emotional health influence your physical well-being? In this video, Kate Tolo shares her personal journey of how addressing emotional barriers helped transform her diet and overall health. Can emotional healing unlock lasting physical health? Watch to discover how emotional health is the key to unlocking a better, healthier you.Kate ToloListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠⁠londonnootropics.com⁠⁠***If you enjoyed this episode you might also like:The FIRST Woman To Follow Bryan Johnson's $2M Anti-Aging Blueprint | Why Kate Tolo Is Differenthttps://youtu.be/BJC_E_gXYMg***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

What does it cost to follow your own map?Dr. Emeran Mayer, pioneer of the mind-gut connection, shares the unexpected choices that defined his life from resisting conformity to overcoming early fears. In this short, reflective episode, he explains why one small change rewired his path and what he still struggles to make peace with.Dr. Emeran MayerListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots⁠**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at ⁠londonnootropics.com⁠***If you enjoyed this episode you might also like:The Gut-Mind Doctor: The Mind & Food Strategies That Can Heal Your Gut Microbiome | Dr. Emeran Mayerhttps://youtu.be/yL5ZtoJAUBs***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Trigger Warning:This episode includes discussion of trauma, suicide, abuse, and emotional processing in the context of psychedelic therapy. Please take care while listening. Viewer discretion is advised.You've been told psychedelics are poison.That healing trauma requires years of talk therapy.What if three sessions could change everything?This week on Live Well Be Well, I sit down with Dr. Rick Doblin, who has spent 39 years fighting for something most people thought impossible: bringing psychedelics back into medicine. As the founder of MAPS (Multidisciplinary Association for Psychedelic Studies), Rick has dedicated his life to proving that MDMA isn't just a party drug. It's a revolutionary treatment for trauma that could change how we understand healing itself.Rick doesn't just speak about psychedelics as science or policy. He's lived them, studied them, and helped thousands heal with them. His work isn't about escapism. It's about going deeper. Into the body. Into memory. Into parts of ourselves we've long avoided. And then, through compassion and skilled integration, coming out the other side, changed.We explore:Rick's first psychedelic experience and what it taught him about interconnectednessHow MDMA works in the brain to reduce fear and increase compassionWhy MDMA may be the most effective tool we have for PTSDThe three-phase therapy protocol and why context matters more than the drug itselfWhat went wrong with FDA approval and why Rick believes approval is inevitableThe difference between a "bad trip" and a meaningful oneWhy people with the most difficult childhoods often show the greatest improvement with MDMA therapyHow patients develop empathy (not forgiveness, but understanding) for their perpetratorsYour trauma doesn't define you. But learning to hold it with compassion might just set you free.Love,Sarah Ann

Sprouts are one of the most nutrient-dense, accessible foods on the planet. In this clip, Doug Evans explains how these tiny plants boost protein, reduce anti-nutrients, and grow without soil or sunlight, making them a simple, powerful upgrade to any diet.Listen to the full episode ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.***If you enjoyed this episode you might also like:The MOST Surprising Food That Fights Disease & Helps With Losing Weight | Doug Evanshttps://youtu.be/YRuYfCmIz74***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

What happens when you achieve everything you set out to, and still feel empty? In this conversation with Simon Sinek, he shares the painful turning point that led to Start With Why, how ADHD became his greatest asset, and why so many exceptional leaders carry hidden struggles. The answers aren't in performance, they're in self-awareness, vulnerability, and knowing how to ask the right questions.Listen to the full episode ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: ⁠Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots***If you enjoyed this episode you might also like:Simon Sinek: The ADHD Superpower - Why It's My Greatest Advantagehttps://youtu.be/_wopj2Qk-4c***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

You've been told your hormones make you irrational.That menopause means cognitive decline, your emotions are just chemistry gone wrong, and your brain is simply too complicated to understand.Science says otherwise.This week's guest, Dr. Sarah McKay, is a neuroscientist, author, and brain health expert who's spent her career dismantling the myths we've been told about women's brains. From the idea that we're slaves to our hormones to the fear that menopause means inevitable decline, Sarah brings data, nuance, and hope to conversations that have been shaped by outdated stereotypes for far too long.We explore:Why male and female brains are more similar than different, and how cultural context shapes the differences we do seeThe surprising truth about PMS: how rates vary from 12% in France to 90% in IranWhy the stereotype that women are "more emotional" isn't backed by scienceHow your brain actually changes during menopauseThe real relationship between hormones, sleep, and brain fogWhy early puberty affects girls and boys so differentlyWhat brain networks do when estrogen declinesThe truth about HRT and brain health: what the data actually showsHow expectations and cultural narratives create the experiences we haveSarah doesn't dismiss women's struggles or minimize real symptoms. Instead, she offers something more powerful: the understanding that our brains are not broken, fragile, or at the mercy of our biology. They're sophisticated, adaptive, and capable of remarkable reorganization throughout our lives.This isn't about toxic positivity or dismissing genuine challenges. It's about recognizing that the stories we've been told about women's brains, that we're irrational, unstable, or declining, aren't just wrong. They're actively shaping our reality.Love,Sarah Ann

Does understanding your menstrual cycle unlock better health, fertility, and performance? In this conversation with Dr. Stacy Sims, she breaks down the four phases of your cycle, reveals why anovulatory cycles are becoming more common, and explains how stress, diet, and lifestyle directly impact your hormones. From tracking your bleed patterns to understanding why women need different nutrition than men, this isn't just about periods. It's about optimizing your entire well-being.Dr. Stacy SimsListen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠.***If you enjoyed this episode you might also like:Dr. Stacy Sims on Perimenopause & How to Manage Symptoms | Fitness and Nutrition for WOMENhttps://www.youtube.com/watch?v=hsaGZXiEbNs&list=PLfXKbjBGaUhb8BME00cxF6YPp1J5EcO7j&index=18***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

What if the drug that could save your life… already exists? In this powerful story from David Fajgenbaum, you'll hear how a man on the brink of death discovered an existing drug, never approved for his illness, that brought him back. But the real shock? No one profits from it, so no one's looking. Learn the hidden world of drug repurposing, AI-driven discovery, and the mission to match life-saving treatments to the people who need them most.Listen to the full episode ⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠.***If you enjoyed this episode you might also like:How AI is Revolutionizing Medicine | The Doctor Who Saved Himself With AI | Dr. David Fajgenbaumhttps://youtu.be/cE4ytfAw614***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠***Let's be friends!

Your gut isn't just about what you eat.It's about how you live, love, feel, and breathe.In this episode of Live Well Be Well, I sit down with Emily Leeming, PhD, gut-brain researcher at King's College London and registered nutritionist whose work bridges the gap between cutting-edge microbiome science and practical wellness, to uncover the hidden forces shaping your microbiome. We go far beyond food and supplements to explore how hormones, intimacy, stress, and human connection are quietly reshaping your gut health every single day.Emily reveals why men and women have fundamentally different gut microbiomes, how a 10-second kiss transfers 80 million microbes between partners, and why stress, trauma, and even loneliness might impact your gut health more than any probiotic.This isn't about achieving perfect gut health. It's about understanding that your microbiome is alive, responsive, and deeply interconnected with how you feel, relate, and move through the world.In this conversation, we explore: • Why men and women experience gut health differently • How estrogen fluctuations and menopause alter women's gut diversity • Why testosterone and sperm quality are linked to gut health in men • The surprising ways sex and cohabitation change your microbiome • How stress, loneliness, and trauma can shrink your microbiome • The emerging connections between ADHD, autism, and gut-brain signaling • Why breathwork is one of the most underrated tools for gut health • The truth about commercial gut testing versus listening to your body • What stool reveals that gut tests don't • The role of polyphenols, fibre & fermented foods in microbial diversity • How gardening, touch, and community naturally diversify your microbesYou'll leave with a completely reframed understanding of gut health. One that honors the emotional, social, and hormonal dimensions of wellness alongside the nutritional ones.Love,Sarah Ann

What if failure isn't the problem, but the solution? In this video, we unpack the neuroscience of fear, failure, and self-compassion. We explore how small changes like a single cup of greens or taking the first uncomfortable step can rewire the brain. This isn't about hacks. It's about mindset, values, and learning to see failure as information, not identity.The Brain DocsListen to the full episode ⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠.***If you enjoyed this episode you might also like:How to Prevent Alzheimer's and Boost Your Brain Health with These PROVEN Foods | The Brain Docshttps://youtu.be/HKEvPm11R3o***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠***Let's be friends!

What if inflammation didn't just come from your diet but from your digital habits? In this clip, Professor Dan Nicolau shares the overlooked connection between attention, immune response, and the subtle biological cost of modern screen use.Dan NicolauListen to the full episode ⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠.Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠.***If you enjoyed this episode you might also like:The Brain Immune Expert: ALERT! Social Media Is Reprogramming Your Immune System | Prof Nicolauhttps://youtu.be/2zNw6pzv8qk***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠***Let's be friends!

⚠️ Trigger Warning: This episode contains discussions of grief, trauma, death, childhood illness (including cancer), and environmental toxins. Listener discretion is advised — particularly for parents and caregivers of children affected by illness.If you've been navigating your health through routines, biohacks, or supplements but still feel disconnected, burnt out, or unwell, this conversation may shift everything.True healing is rarely about control. And it's almost never linear.In this episode, I sit down with Dr. Zach Bush, a triple board-certified physician in internal medicine, endocrinology, and hospice care, and founder of regenerative health company Farmer's Footprint, to rethink everything we've been told about medicine, longevity, and what it means to feel whole. Dr. Zach's research reveals how the human gut microbiome contains more biodiversity than any other ecosystem on Earth, including rainforests and coral reefs, and how this internal garden directly influences our capacity for creative thought, emotional resilience, and physical healing.This isn't just about symptoms or protocols. It's about connection to nature, to others, and most of all, to yourself.We explore how modern health has become more fragmented than ever, and why the root of healing might be much quieter, much simpler, and much more human than we've been led to believe. Dr. Zach explains how your body regenerates your entire gut lining every three days, why stress hormones function as internal antibiotics that destroy beneficial bacteria, and how forest bathing measurably shifts your nervous system from sympathetic overdrive to parasympathetic healing, which is why Japan now prescribes it as first-line treatment for depression.Together, we explore: • Why the body is always healing at rates we can barely comprehend, unless we get in the way • How the gut's biodiversity mirrors the richness of our inner and outer environments • What real nourishment means (and why food prepared with love heals differently than nutrients consumed alone) • The specific physiological changes that occur during forest bathing and why biodiversity exposure enhances creativity • How to practice presence in your body as medicine • Why multi-generational living is the only consistent factor across all Blue Zones for longevity • And why stillness, beauty, and presence are not luxuries but essential medicineYou'll come away with a deeper understanding of your body not as a project to manage, but as an ecosystem to listen to. Plus practical tools for reconnecting with the healing intelligence that's been with you all along. And maybe, like me, you'll find yourself exhaling, softening, and remembering what it means to live well and be well.Love,Sarah Ann