Podcasts about Permutation

Episode 166 Chapter 26, Early Computer Music (1950–70). Works Recommended from my book, Electronic and Experimental Music  Welcome to the Archive of Electronic Music. This is Thom Holmes. This podcast is produced as a companion to my book, Electronic and Experimental Music, published by Routledge. Each of these episodes corresponds to a chapter in the text and an associated list of recommended works, also called Listen in the text. They provide listening examples of vintage electronic works featured in the text. The works themselves can be enjoyed without the book and I hope that they stand as a chronological survey of important works in the history of electronic music. Be sure to tune-in to other episodes of the podcast where we explore a wide range of electronic music in many styles and genres, all drawn from my archive of vintage recordings. There is a complete playlist for this episode on the website for the podcast. Let's get started with the listening guide to Chapter 26, Early Computer Music (1950–70).  from my book Electronic and Experimental music.   Playlist: EARLY COMPUTER MUSIC (1950–70)   Time Track Time Start Introduction –Thom Holmes 01:40 00:00 1.     Tones from Australia, 1951. All produced using the CSIR Mark 1 computer built at the CSIR's radio-physics division in Sydney. The computer had a speaker—or hooter—to signal when operations were completed. A clever programmer thought of manipulating the signal tones into a melody. 02:18 01:42 2.     Alan Turing's computer music. 1951. Recording made of tones generated by the mainframe computer at the Computing Machine Laboratory in Manchester, England. Snippets of the tunes God Save the King, Baa, Baa Black Sheep, and Glenn Miller's swing classic In the Mood. Plus, the voices of computer lab members listening to the sound as it was recorded. Original acetate recording from 1951 restored by University of Canterbury composer Jason Long and Prof Jack Copeland. 01:55 02:36 3.     Max Mathews, “Numerology” (1960). Introduced by a narrator. From the album Music From Mathematics, Bell Telephone Laboratories. While working at Bell Labs in telecommunications research, Max Mathews was one of the earliest computer engineers to use a general-purpose computer to program music and digitally synthesize musical sound. His programming language Music I allowed composers to design their own virtual instruments, a breakthrough during those pioneering days of computer music. “Numerology” was composed to demonstrate the various parameters, or building blocks, available to the composer using this programming language: vibrato (frequency modulation), attack and decay characteristics, glissando, tremolo (amplitude modulation), and the creation of new waveshapes. 02:49 04:38 4.     John Robinson Pierce, “Beat Canon” (1960). Introduced by a narrator. From the album Music From Mathematics, Bell Telephone Laboratories. Played by IBM computer and direct to digital sound transducer. 00:52 07:28 5.     James Tenney, “Noise Study” (1961). So named because “each of the ‘instruments' used in this piece includes a noise-generator.” 04:24 08:20 6.     “Bicycle Built For Two (Accompanied)” (1963) From the demonstration record Computer Speech - Hee Saw Dhuh Kaet (He Saw The Cat), produced by Bell Laboratories. This recording contains samples of synthesized speech–speech artificially constructed from the basic building blocks of the English language. 01:17 12:42 7.     Lejaren Hiller, “Computer Cantata, Prologue to Strophe III” (1963). From the University Of Illinois. This work employed direct computer synthesis using an IBM 7094 mainframe computer and the Musicomp programming language. 05:41 14:00 8.     J. K. Randall, “Lyric Variations For Violin And Computer” (1965-1968). J. K. Randall's piece had a complex section that pushed the limits of computer processing power at the time. Although the section consisted of only 12 notes, each note was 20 seconds long. Each note overlapped with the next for 10 seconds, making the total length of the section only about 2 minutes. But this required 9 hours to process on one of the fastest computers of the day. 03:34 19:40 9.     John Robinson Pierce, “Eight-Tone Canon” (1966). “Using the computer, one can produce tones with overtones at any frequencies.” Produced at Bell Telephone Laboratories. 03:53 23:14 10.   Pietro Grossi, “Mixed Paganini” (1967). “Transcription for the central processor unit of a GE-115 computer of short excerpts of Paganini music scores. Realized at Studio di Fonologia musicale di Firenze (Italy). 01:46 27:08 11.   Pietro Grossi, “Permutation of Five Sounds” (1967). Recording made on the Italian General Electric label. Realized at Studio di Fonologia musicale di Firenze (Italy). Distributed in 1967 as a New year gift by Olivetti company. 01:33 28:54 12.   Wayne Slawson, “Wishful Thinking About Winter” (1970). Produced at Bell Telephone Laboratories. 03:53 30:26 13.   John Cage and Lejaren Hiller, “HPSCHD” excerpt (1967-1969). The piece was written for Harpsichords and Computer-Generated Sound Tapes. Hiller and Cage staged a lively public performance in 1968 at the University of Illinois in Urbana. The first 10,000 individual recordings came with an insert in the form of a computer printout insert designed to allow the listener to program their own performance. And I quote from the jacket: "The computer-output sheet included in this album is one of 10,000 different numbered solutions of the program KNOBS. It enables the listener who follows its instructions to become a performer of this recording of HPSCHD. Preparation of this material was made possible through the Computing Center of the State University of New York at Buffalo." I happen to have three copies of this album, each with the printout. 07:20 34:16 14.   Jean-Claude Risset, “Computer Suite From "Little Boy" (1968).  Realized at Bell Laboratories. 04:28 41:46 15.   Peter Zinovieff, “January Tensions” (1968). Zinovieff's notes, from the album: “Computer composed and performed. This piece is very much for computer both in its realization and composition. The rules are straightforward. The computer may begin by improvising slowly on whatever material is first chooses. However, once the initial choices are made then these must influence the whole of the rest of the composition. The original sounds must occasionally be remembered and illustrated but a more and more rigid structure is imposed on the randomness. The piece was electronically realized and composed in real time by an 8K PDP8/S and electronic music peripherals.” 09:48 46:12 16.   Barry Vercoe, “Synthesism” (1969). Realized in the Computer Centers of Columbia and Princeton Universities using MUSIC 360 for the IBM 360 mainframe computer. Vercoe authored this musical programming language. 04:33 56:00 17.   Charles Dodge, “The Earth's Magnetic Field” excerpt (1970). Composer Charles Dodge helped close the gap between computer music and other electronic music practices in 1969– 70 by working on computer code at Princeton University and then traveling to Bell Labs to have the code synthesized by a mainframe computer. The work, “Earth's Magnetic Field” (1970) was an outcome of this process. Dodge realized this piece by fusing computer composition with synthesis, one of the earliest examples of a practice that would become the norm many years later but that was quite difficult at the time. He used a “general- purpose sound synthesis program” written by Godfrey Winham at Princeton University. Every sound in the piece was computed into digital form using the IBM/ 360 model 91 at the Columbia University Computer Center and then converted into analog form at the Bell Telephone Laboratories. 07:45 01:00:32 18.   Irv Teibel, "Tintinnabulation (Contemplative Sound)" from Environments (New Concepts In Stereo Sound) (Disc 2) (1970 Syntonic Research).  One side of the record is a rare work of purely electronic computer music in a series that otherwise consisted of natural ambient sounds. It used computer-generated bell sounds, falling back on Teibel's experience processing sounds on an IBM 360 mainframe computer at Bell Labs. The record was promoted for meditation. A sticker on the cover read, "A Sensitizer for the Mind." From the liner notes: “As an illustration of the possibilities currently under examination, Syntonic Research decided to experiment with bell sounds as an environmental sound source. . . . Tintinnabulation can be played at any speed, from 78 to 16 rpm, in full stereo. At different speeds, the sounds change in tone and apparent size, although the harmonics remain unchanged. The effect, unlike real bells, is fully controllable by the use of your volume, bass, and treble controls.” 30:10 01:08:16   Additional opening, closing, and other incidental music by Thom Holmes. My Books/eBooks: Electronic and Experimental Music, sixth edition, Routledge 2020. Also, Sound Art: Concepts and Practices, first edition, Routledge 2022. See my companion blog that I write for the Bob Moog Foundation. For a transcript, please see my blog, Noise and Notations. Original music by Thom Holmes can be found on iTunes and Bandcamp.

"The Strangest Security Tape I've Ever Seen" written by powerhawkmash  "Diluted" written by Hattey TRIGGER WARNINGS AVAILABLE AT BOTTOM OF SHOW NOTES. MAY CONTAIN SPOILERS. LinkTree for all of my social media, YouTube, Patreon etc. Leave me a voice mail! ‪(323) 546-8764‬ Ad Free version and bonus episodes available on Patreon You can send your stories to: scareyoutosleep@gmail.com Music by Epidemic Sound and Co.AG TW: Story 2 “Diluted”: Harm to a mass of people in a public space Learn more about your ad choices. Visit megaphone.fm/adchoices

"The Strangest Security Tape I've Ever Seen" written by powerhawkmash  "Diluted" written by Hattey TRIGGER WARNINGS AVAILABLE AT BOTTOM OF SHOW NOTES. MAY CONTAIN SPOILERS. LinkTree for all of my social media, YouTube, Patreon etc. Leave me a voice mail! ‪(323) 546-8764‬ Ad Free version and bonus episodes available on Patreon You can send your stories to: scareyoutosleep@gmail.com Music by Epidemic Sound and Co.AG TW: Story 2 “Diluted”: Harm to a mass of people in a public space Learn more about your ad choices. Visit megaphone.fm/adchoices

The Love Train is unusually eclectic Saturday at 1 PM... DJ Permutation took a deep dive in the record bin, and found some post-punk dub with New Age Steppers, Roma hip hop with Azucar Moreno, Swedish rap with Just D, bookended by Funky Nassau and a little bit of House. Funky it will be!

The Love Train is going full DISCO for this episode. Kicking off with les grande dames Esther Phillips, Bettye LaVette and Anita Ward, then Salsoul, Frankie Smith and more... with Hot Chocolate on top. All vinyl, mixed with love. Yum.Original air date Saturday 2.17.2024 at 1 pm (est) on WOZO-LP 103.9 FM Radio in Knoxville, TN and streamed online at wozoradio.com

This is episode 34 of The Love Train Show with Dj Permutation that aired on Saturday February 10th, 2024 at 1 pm on WOZO-LP 103.9 FM radio in Knoxville, TN USA and streamed online at wozoradio.com Please consider a donation to help keep Knoxville's only true noncommercial nonprofit community run radio on the air. Our Venmo is WOZOFM and there is a paypal link on our website. Thank you!

This is The Love Train Show with Dj Permutation taht aired on Saturday February 3rd, 2024 at 1 pm on WOZO-LP 103.9 FM Radio in Knoxville TN and streamed online at wozoradio.com This is episode 033. Loaded with 70's and 80s soul, funk and RnB... Eddie Kendricks, The Bar-Kays, Isley Brothers, Gap Band, and an EDM prototype track from Planet Patrol. Wow.If you like this episode, please consider a financial donation to help wozo remain on the air. The Station's Venmo is WOZOfm and there is a paypal link on the website. Thank you.

This is the episode of The Love Train with Dj Permutation that aired Saturday January 6th 2024 at 1 pm mon WOZO-lp 103.9 fm in Knoxville, TN and streamed online at wozoradio.com it is described as:First Love Train of 2024, -Put the Needle on the Record! Rather funky with James Brown, an Earth, Wind & Fire mashup, Johan Kinde and Kym Mazelle. Nona Hendryxx early EDM remake of "Do What You Wanna Do" is S M O K I N G. Phew.

Connor runs down the different possibilities in the NFL this weekend. Wild scenarios are still in play for our nation's greatest sport.

In episode 37 of the quantum consciousness series, Justin Riddle takes a deep dive into Donald Hoffman's conscious agent model and relates it to the leading theories of quantum consciousness. The structure of this episode is an introduction to Hoffman's model of conscious agents, then an interview with Don Hoffman in November 2022, and finally some reflections on the implications of this model. Hoffman begins by describing the interface theory of perception: we have mistaken the external “physical” world to be fundamental reality. But this external world that we see around us is an evolved interface that was created through billions of years of evolution and cannot be trusted. The world you experience is like a video game – with icons, side quests, and abstract motivations to win victory points. The “real” world is not directly accessible to us through our perceptual systems and there is a great illusion at play. Hoffman then proposes his Conscious Agents theory, in which the universe is comprised of conscious beings interacting with each other. He describes these conscious agents as Markov Chains – probabilistic systems that move through a set of possible experience and action states while learning from their interactions with the world at large. Finally, he proposes that conscious agents are composed of conscious agents resulting in a fractal nested hierarchy of beings from the scale of the entire universe down to the Planck scale. This nested hierarchy is fundamental and now just needs to be mapped into modern particle physics in order to complete his theory of everything. Here, he introduces “decorated permutations” which are a way to map the Markov Models of his conscious agents into geometric structures. With this mapping, he claims to connect his agents to fundamental geometric forms at the core of reality, such as the amplituhedron, and then that amplituhedron can derive space-time, particle physics, and quantum mechanics. His theory is very Platonist in its essence and relies on a geometric depiction of reality. At the end of the episode, I praise the ability of Hoffman's theory to connect the nested hierarchies of beings into a substrate for mathematical forms to arise, but also caution that his model throws away the physical world and mental world to some degree to focus exclusively on the Platonic world of forms. Living within a hyperdimensional geometric form may result in the same nihilistic conclusions that our lives are just unfolding as sub-projections of this universal form. Can we salvage the human spirit from unmoving crystalline geometry? I hope you enjoy!

“Hear the sum of the whole matter in the compass of one brief word — every art possessed by man comes from Prometheus.” ― Aeschylus, Prometheus Bound https://rkblog.com/

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.31.535153v1?rss=1 Authors: Koenig, S. D., Safo, S., Miller, K. J., Herman, A. B., Darrow, D. P. Abstract: Background: Time series analysis is critical for understanding brain signals and their relationship to behavior and cognition. Cluster-based permutation tests (CBPT) are commonly used to analyze a variety of electrophysiological signals including EEG, MEG, ECoG, and sEEG data without a priori assumptions about specific temporal effects. However, two major limitations of CBPT include the inability to directly analyze experiments with multiple fixed effects and the inability to account for random effects (e.g. variability across subjects). Here, we propose a flexible multi-step hypothesis testing strategy using CBPT with Linear Mixed Effects Models (LMEs) and Generalized Linear Mixed Effects Models (GLMEs) that can be applied to a wide range of experimental designs and data types. Methods: We first evaluate the statistical robustness of LMEs and GLMEs using simulated data distributions. Second, we apply a multi-step hypothesis testing strategy to analyze ERPs and broadband power signals extracted from human ECoG recordings collected during a simple image viewing experiment with image category and novelty as fixed effects. Third, we assess the statistical power differences between analyzing signals with CBPT using LMEs compared to CBPT using separate t-tests run on each fixed effect through simulations that emulate broadband power signals. Finally, we apply CBPT using GLMEs to high-gamma burst data to demonstrate the extension of the proposed method to the analysis of nonlinear data. Results: First, we found that LMEs and GLMEs are robust statistical models. In simple simulations LMEs produced highly congruent results with other appropriately applied linear statistical models, but LMEs outperformed many linear statistical models in the analysis of suboptimal data and maintained power better than analyzing individual fixed effects with separate t-tests. GLMEs also performed similarly to other nonlinear statistical models. Second, in real world human ECoG data, LMEs performed at least as well as separate t-tests when applied to predefined time windows or when used in conjunction with CBPT. Additionally, fixed effects time courses extracted with CBPT using LMEs from group-level models of pseudo-populations replicated latency effects found in individual category-selective channels. Third, analysis of simulated broadband power signals demonstrated that CBPT using LMEs was superior to CBPT using separate t-tests in identifying time windows with significant fixed effects especially for small effect sizes. Lastly, the analysis of high-gamma burst data using CBPT with GLMEs produced results consistent with CBPT using LMEs applied to broadband power data. Conclusions: We propose a general approach for statistical analysis of electrophysiological data using CBPT in conjunction with LMEs and GLMEs. We demonstrate that this method is robust for experiments with multiple fixed effects and applicable to the analysis of linear and nonlinear data. Our methodology maximizes the statistical power available in a dataset across multiple experimental variables while accounting for hierarchical random effects and controlling FWER across fixed effects. This approach substantially improves power and accuracy leading to better reproducibility. Additionally, CBPT using LMEs and GLMEs can be used to analyze individual channels or pseudo-population data for the comparison of functional or anatomical groups of data. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.27.530244v1?rss=1 Authors: Veillette, J. P., Ho, L., Nusbaum, H. C. Abstract: Cognitive neuroscientists have been grappling with two related experimental design problems. First, the complexity of neuroimaging data (e.g. often hundreds of thousands of correlated measurements) and analysis pipelines demands bespoke, non-parametric statistical tests for valid inference, and these tests often lack an agreed-upon method for performing a priori power analyses. Thus, sample size determination for neuroimaging studies is often arbitrary or inferred from other putatively but questionably similar studies, which can result in underpowered designs -- undermining the efficacy of neuroimaging research. Second, when meta-analyses estimate the sample sizes required to obtain reasonable statistical power, estimated sample sizes can be prohibitively large given the resource constraints of many labs. We propose the use of sequential analyses to partially address both of these problems. Sequential study designs -- in which the data is analyzed at interim points during data collection and data collection can be stopped if the planned test statistic satisfies a stopping rule specified a priori -- are common in the clinical trial literature, due to the efficiency gains they afford over fixed-sample designs. However, the corrections used to control false positive rates in existing approaches to sequential testing rely on parametric assumptions that are often violated in neuroimaging settings. We introduce a general permutation scheme that allows sequential designs to be used with arbitrary test statistics. By simulation, we show that this scheme controls the false positive rate across multiple interim analyses. Then, performing power analyses for seven evoked response effects seen in the EEG literature, we show that this sequential analysis approach can substantially outperform fixed-sample approaches (i.e. require fewer subjects, on average, to detect a true effect) when study designs are sufficiently well-powered. To facilitate the adoption of this methodology, we provide a Python package "niseq" with sequential implementations of common tests used for neuroimaging: cluster-based permutation tests, threshold-free cluster enhancement, t-max, F-max, and the network-based statistic with tutorial examples using EEG and fMRI data. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Insight source: The Spiral of Time series by Rav Dovber Pinson --- Send in a voice message: https://anchor.fm/emeteliram/message

REST OF 7II II7 | 7TH SDA EVENT PSALMS 69 DAMASCUS SYRIA ZION JERUSALEM Vindication or Validation “Therefore thus says the Lord: I have returned to Jerusalem with compassion (lovingkindness and mercy). My house shall be built in it, says the Lord of hosts, and a measuring line shall be stretched out over Jerusalem [with a view to rebuilding its walls]. ‭‭Zechariah‬ ‭1‬:‭16 “Then I will encamp about My house as a guard or a garrison so that none shall march back and forth, and no oppressor or demanding collector shall again overrun them, for now My eyes are upon them. Zechariah‬ ‭9‬:‭8 Cry yet again, saying, Thus says the Lord of hosts: My cities shall yet again overflow with prosperity, and the Lord shall yet comfort Zion and shall yet choose Jerusalem.” ‭‭Zechariah‬ ‭1‬:‭17 Return to the stronghold [בִּצָּרוֹן biṣ·ṣā·rôn fortified place, castle of security and prosperity], you prisoners of hope; even today do I declare that I will restore double your former prosperity to you. [Ps. 40:2; Isa. 40:2.]” ‭‭‬Zechariah‬ ‭9‬:‭12‬ ‭ “For the law was given through Moses, but grace and truth came about through Jesus Christ.”‭‭ John‬ ‭1‬:‭17‬ “Your throne, O God, is forever and ever; the scepter of righteousness is the scepter of Your kingdom.” ‭‭Psalm‬ ‭45‬:‭6‬ “A glorious throne, set on high from the beginning, Is the place of our sanctuary (the temple).” Jeremiah‬ ‭17‬:‭12‬ ‭‬‬ late Middle English (in the sense ‘exchange, barter'): via Old French from Latin permutatio(n-), from the verb permutare ‘change completely' Permutation has not changed all that much since it was borrowed into Middle English from Anglo-French as permutacioun, meaning "exchange, transformation." Permutacioun traces back to the Latin verb permutare, meaning "to change thoroughly, exchange," and ultimately derives from the Latin mutare, "to change." Other descendants of mutare in English include commute, mutant, and mutual. Permutation also has a specific application in the field of mathematics relating to the ordering of a given set of objects. For example, permutations of items a, b, and c are abc, acb, bac, etc. The essence is the restoration | Tikkun and consummation | Olam of God's kingdom. Glorification | The Final Frontier Going Boldly Where The Last Man has Gone Before! Decrease time over target:  PayPal or Venmo @clastronaut Cash App $clastronaut

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.14.516465v1?rss=1 Authors: Pisani, S., Gunasekera, B., Lu, Y., Vignando, M., ffytche, D., Aarsland, D., Chaudhuri, K. R., Ballard, C., Lee, J.-Y., Kim, Y. K., Velayudhan, L., Bhattacharyya, S. Abstract: Background: Common neural underpinning of Parkinson's Disease (PD) psychosis across different structural magnetic resonance imaging (MRI) studies remains unclear to this day with few studies and even fewer meta-analyses available. Objectives: Our meta-analysis aimed to identify and summarise studies using MRI approach to identify PD psychosis-specific brain regions and examine the relation between cortical volume loss and dopaminergic and serotonergic receptor density. Methods: PubMed, Web of Science and Embase were searched for MRI studies of PD psychosis (PDP) compared to PD patients without psychosis (PDnP). Seed-based d Mapping with Permutation of Subject Images was applied in the meta-analysis where coordinates were available. Multiple linear regressions to examine the relationship between grey matter volume loss in PDP and receptor gene expression density (extracted from the Allen Human Brain Atlas) were conducted in R. Results: We observed lower grey matter volume in parietal-temporo-occipital regions from our meta-analysis (N studies =10, PDP n=211, PDnP, n=298). These results remained significant after adjusting for PD medications and for cognitive scores. Grey matter volume loss in PDP was associated with local expression of 5-HT1a (b=0.109, p=0.012) and 5-HT2a receptors (b=-0.106, p=0.002) also after adjusting for PD medications (5-HT1a, p = 0.005; 5-HT2a, p = 0.001). Conclusions: Widespread cortical volume loss in the parieto-temporo-occipital regions involved in information processing and integration, as well as attention, could result in PD psychosis symptoms. Neurobiological mechanisms implicating serotonergic receptors may also contribute to this condition. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

El capítulo final de esta gran aventura con Draco Studios, los héroes se enfrentan a su última prueba en la luna roja de Draka.  ¿Podrán con el majestuoso e inteligente Kuxcoatl?  Conoce todo lo que está haciendo Draco Studios aquí: https://www.backerkit.com/call_to_action/d40390e6-f2db-4470-b882-de307e15a5d5/landing?ref=TRpodcast https://linktr.ee/DracoStudios Sigue nuestra campaña de DnD en todas las redes sociales Facebook: https://www.facebook.com/TirandoRol1 Twitter: https://twitter.com/Tirando_Rol Instagram: https://www.instagram.com/tirando_rol1/ Música: Alexander Nakarada vía Patreon Tabletop Audio

Amon Tobin is an innovative electronic music producer specializing in sound design and production techniques.Arriving on the English scene in 1997, Amon's construction of jazz inspired, sampled driven output inspired listeners and critics alike.Amon Tobin has garnered substantial notoriety for his advanced production methods and cinematic compositions."Roots to Grooves" is a production of SIGNL.https://www.signlradio.comhttps://www.instagram.com/signlradiohttps://www.twitter.com/signlradiohttps://www.facebook.com/signlradiohttps://www.mixcloud.com/signlhttps://open.spotify.com/user/96mhz6qfjoztxbl2dpm0uj903?si=aAZpsoEnRAKdx85kr1QWhg

Nuestros héroes están dándolo todo en las habitaciones de la pirámide, pero cada reto y cada habitación se pone mucho más complicada que la anterior ¿Podrán sobrevivir? O peor ¿Qué pasará después de terminar de recorrer estas habitaciones? Conoce todo lo que está haciendo Draco Studios aquí: https://www.backerkit.com/call_to_action/d40390e6-f2db-4470-b882-de307e15a5d5/landing?ref=TRpodcast https://linktr.ee/DracoStudios Sigue nuestra campaña de DnD en todas las redes sociales Facebook: https://www.facebook.com/TirandoRol1 Twitter: https://twitter.com/Tirando_Rol Instagram: https://www.instagram.com/tirando_rol1/ Música: Alexander Nakarada vía Patreon Tabletop Audio

Los héroes han entrado a la pirámide de la iluminación, un lugar tan lleno de conocimientos como de peligros ¿Podrán encontrar una salida? ¿Encontrarán quién los trajo a este lugar y por qué? O la pirámide será su último lugar de descanso Conoce todo lo que está haciendo Draco Studios aquí: https://linktr.ee/DracoStudios Sigue nuestra campaña de DnD en todas las redes sociales Facebook: https://www.facebook.com/TirandoRol1 Twitter: https://twitter.com/Tirando_Rol Instagram: https://www.instagram.com/tirando_rol1/ Música: Alexander Nakarada vía Patreon Tabletop Audio

El paisaje brilla lleno de estrellas, pero la confusión crece, estos cuatro héroes están muy lejos de casa, pero, por más hermosa que sea la vista, es urgente salir ¿Que habrá al final de estas escaleras? Conoce todo lo que está haciendo Draco Studios aquí: https://linktr.ee/DracoStudios Sigue nuestra campaña de DnD en todas las redes sociales Facebook: https://www.facebook.com/TirandoRol1 Twitter: https://twitter.com/Tirando_Rol Instagram: https://www.instagram.com/tirando_rol1/ Música: Alexander Nakarada vía Patreon Tabletop Audio

Cuatro extraños despiertan en una habitación, sus recuerdos están borrosos y el lugar en el que se encuentran es bastante extraño ¿Qué diablos está sucediendo? ¿Están en peligro? Lo importante es trabajar en equipo y averiguar que sucede. Conoce todo lo que está haciendo Draco Studios aquí: https://linktr.ee/DracoStudios  Sigue nuestra campaña de DnD en todas las redes sociales Facebook: https://www.facebook.com/TirandoRol1 Twitter: https://twitter.com/Tirando_Rol Instagram: https://www.instagram.com/tirando_rol1/ Música: Alexander Nakarada vía Patreon Tabletop Audio

In this work, we present a symbolic symphony music generation solution, SymphonyNet, based on a permutation invariant language model. To bridge the gap between text generation and symphony generation task, we propose a novel Multi-track Multi-instrument Repeatable (MMR) representation with particular 3-D positional embedding and a modified Byte Pair Encoding algorithm (Music BPE) for music tokens. A novel linear transformer decoder architecture is introduced as a backbone for modeling extra-long sequences of symphony tokens. 2022: Jiafeng Liu, Yuanliang Dong, Zehua Cheng, Xinran Zhang, Xiaobing Li, Feng Yu, Maosong Sun Ranked #1 on Audio Generation on Symphony music https://arxiv.org/pdf/2205.05448v1.pdf

We discussed the Premier League title race, the top 4 race and the relegation battle, the crew also discussed the Scudetto title and top 4 race in the Uber Eats League

The Signal is Lost in Space ;) time for permutation! I stopped my contribution to Evosonic, thank u! my Show will continue under https://hearthis.at/thepermutation/ And Twitch (Coming Soon) so I will continue mix Weekly you may Like to follow me over there This Stream will end after 30 mins please Switch over to The Permutation stream

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Dis weer tyd vir Francois se boekklub. Diekeer praat ons oor Greg Egan se Permutation city. Greg Egan se webwerf Wiki artikel oor Permutation City

Amon Tobin on the Virtual Sessions presented by The DJ Sessions 12/14/21 About Amon Tobin - Amȯn Tȯbin was born in Brazil, but spent his formative years in the UK. He came up through the breakdancing and hip-hop scenes in the 1980s, and the jungle and drum and bass scenes of the 1990s, before establishing a sound and a style that was singularly his own. He first emerged with a string of 12" singles on the small London label 9Bar Records, and his breakthrough first album, Adventures in Foam, led to his signing to Ninja Tune in 1996. For the next several years, he pushed the boundaries of found sound to the limits in acclaimed albums such as Bricolage (1997), Permutation (1998), Supermodified (2000), and out from out Where (2002), and pushed other compositional tactics forward in albums like Foley Room (2007) and ISAM (2011). Foley Room explored the role of sound design and field recordings, culminating in an acclaimed performance at the birthplace of musique concrete, the GRM in Paris. He also produced several original scores, ranging from the cult film Taxidermia to the video game blockbuster Splinter Cell: Chaos Theory, and created numerous dancefloor-oriented singles and albums under the alias Two Fingers. Tobin's 2011 album ISAM, an acronym for "Invented Sound Applied to Music," utilized advanced synthesis processing and production techniques traditionally reserved for sound design in film. It proved an influential contribution towards recent approaches to music production in electronic music. It also paved the way for a radically new kind of audiovisual performance. Hailed by major media outlets including Wired, Rolling Stone, NPR, and many others around the world, ISAM received global acclaim as a landmark in audiovisual performance. Projection mapping, which had been the domain of static and mostly corporate visual showcases, was configured for the first time to uniquely narrate the musical performance of an album. ISAM reshaped audience's expectations of electronic music concerts, and premiered at some of the world's most prestigious venues, from the Sydney opera House to the olympia in Paris to the London Hammersmith, and many international festivals including Sonar, MUTEK and Moogfest. The depth and scope of Amon Tobin's work have been a major inspiration to many. From the Kronos Quartet to Diplo, he achieved respect among artists within and outside electronic music. He established a reputation for musical ingenuity unconfined by genre, and over two decades remains one of the most visionary electronic artists of his generation. — Geeta Dayal About The DJ Sessions - With over 2,200 episodes produced over the last eleven years “The DJ Sessions”, a Twitch and Mixcloud “Featured Partner”, has featured international artists such as: BT, Robert Babicz, Camo & Krooked, Amon Tobin, SNBRN, Simon Patterson, Lindsey Stirling, Mako, Morgan Page, Jes, Cut Chemist, Yves Larock, Judge Jules, DubFX, DJs From Mars, Rudosa, Thievery Corporation, Sander Van Dorn, GAWP, Hollaphonic, Kissy Sell Out, Somna, David Morales, Roxanne, JB & Scooba, Massimo Vivona, Moulinx, Futuristic Polar Bears, Many Few, Joe Stone, Reboot, Truncate, Scotty Boy, Jody Wisternoff, Benny Bennasi, Dance Loud, Christopher Lawrence, Oliver Twizt, Ricardo Torres, Alex Harrington, 4 Strings, Sunshine Jones, Elite Force, Revolvr, Kenneth Thomas, Paul Oakenfold, George Acosta, Reid Speed, TyDi, Donald Glaude, Jimbo, Ricardo Torres, Hotel Garuda, Bryn Liedl, Rodg, Kems, Mr. Sam, Steve Aoki, Funtcase, Dirtyloud, Marco Bailey, Thousand Fingers, Dirtmonkey, Crystal Method, Beltek, Dyro, Andy Caldwell, Darin Epsilon, Kyau & Albert, Kutski, Vaski, Moguai, Blackliquid, Sunny Lax, Matt Darey, and many more. In addition to featuring national/international artists “The DJ Sessions” featured hundreds local top DJs from their homebase of Seattle. We have also undergone a massive upgrade in our TDJS studios and to our TDJS Mobile Studio to full HD streaming and HD audio to make the quality of the shows even better than before. Along with that we have launched a new website that now features our current live streams and past episodes in a much more user friendly mobile/social environment. About The DJ Sessions Event Services - TDJSES is a WA State Non-profit charitable organization that's main purpose is to provide music, art, fashion, dance, and entertainment to local and regional communities via events and video production programming distributed through broadcast television and the internet for live and archival viewing. "The DJ Sessions" is a Twitch "Featured Partner" and MixCloud "Featured Partner" series and has been recognized by Apple twice as a "New and Noteworthy" and "Featured Video” podcast. UStream and Livestream have also listed TDJS as a "Featured" stream in their lineups. The TDJS combined live streaming/podcast audience is over 125,000 viewers per week. For all press inquiries regarding “The DJ Sessions”, or to schedule an interview with Darran Bruce, please contact us at info@thedjsessions.com

Roanoke helps criminals disappear, however it seems Roanoke has disappeared himself. Plus Liz finally chooses a side.  Support the Show! Be sure to #FillTheFedora on Patreon. Case Profile for #139 Roanoke Katarina and Liz are teaming up to get the answers they have been searching for their entire lives and in the season opener they need this week’s blacklister Roanoke to help them out.   A criminal mastermind that helps other criminals disappear, Roanoke is tasked with helping Katarina with her escape plan, or so the FBI thinks. Turns out Roanoke is living his life out in a nursing home and Katarina has used the man’s name to invoke a plan to kidnap her father and Liz’s grandfather Dom, right from under Red’s nose.  Meanwhile the task force is is played like a fiddle in this elaborate scheme all the way up to the bitter end when Liz and Ressler finally connect face to face, literally.  Having chosen her side will Liz get the answers she is seeking?  Will we finally learn the truth behind Red? Who is the mysterious N-13 agent and what does any of it have to do with the Sikorski Archive?  All great questions as we jump both feet in to season 8 of the Blacklist.  Be sure to answer our profiling question of the week: Given this week's episode who do you think Red is? Visit our feedback page to leave a response or call +1 (304) 837-2278. Roanoke in Pictures Here are a just a few of our favorite scenes from this week. Red's Rhetoric for Roy Cain Welcome to Red’s Rhetoric that part of the show where we relive some of those wise or witty stories from Red that may or may not have greater significance not only in the show but also in life.  Then you can vote for your favorite here. This week our first story comes when Red is enamored by a cat. Our second comes when Red and Cooper have a parenting conversation on how best to raise Liz. Which was your favorite? If you want to rescue all the crying kittens vote #RedCat or if you truly know what lies ahead for Liz vote #RedDestiny. The Music for Roanoke Season 8 opens with a little jazzy swing from Amon Tobin and the song “Bridge” off his Permutation album from 1998.  We finish the episode with the classic and only version of “Landslide” that should ever be played from Fleetwood Mac as Keenler fans scream in delight around the world.   You can hear these songs via the official Blacklist playlist on Spotify or the same playlist recreated by us on Apple Music.  Keep Connected Each week of The Blacklist Exposed will take a deep look at both the minor and major plot lines to this fantastic series. Be sure to subscribe and review us in Apple Podcasts, Stitcher, or through whichever podcast app you prefer. Also check out our other Golden Spiral Media Podcasts. A special thanks to Veruca Crews for creating our podcast cover art. If you love it, be sure to check out the rest of her Blacklist and other artwork on her tumblr page. Thanks for listening! We’ll talk to you soon. In the meantime, be sure to keep yourself off, The Blacklist.  Send Us Feedback: Check out our Feedback Form! Call our voicemail: (304)837-2278 Email Us Connect With Us: Facebook Community Twitter Instagram Tumblr Troy's Twitter Aaron's Twitter Subscribe to The Blacklist Exposed: Apple Podcasts,  Google Podcasts,  Spotify,  Pandora,  RSS Feed

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.28.360099v1?rss=1 Authors: Nonis, S. G., Haywood, J., Schmidberger, J. W., Bond, C. S., Mylne, J. S. Abstract: Over 30 years ago, an intriguing post-translational modification was discovered to be responsible for creating concanavalin A (conA), a carbohydrate-binding protein found in the seeds of jack bean (Canavalia ensiformis) and commercially used for carbohydrate chromatography. Biosynthesis of conA involves what was then an unprecedented rearrangement in amino acid sequence, whereby the N-terminal half of the gene-encoded conA precursor is swapped to become the C-terminal half of conA. The cysteine protease, asparaginyl endopeptidase (AEP), was shown to be involved, but its mechanism was not fully elucidated. To understand the structural basis and consequences of conA circular permutation, we generated a recombinant jack bean conA precursor (pro-conA) plus jack bean AEP (CeAEP1) and solved crystal structures for each to 2.1 [A] and 2.7 [A] respectively. By reconstituting the biosynthesis of conA in vitro, we prove CeAEP1 alone can perform both the cleavage and cleavage-coupled transpeptidation to form conA. CeAEP1 structural analysis reveals how it is capable of carrying out both these reactions. Biophysical assays illustrated that conA is more thermally and pH stable than pro-conA, consistent with fewer intermolecular interactions between subunits in the pro-conA crystal structure. These findings elucidate the consequences of circular permutation in the only post-translation example known to occur in nature. Copy rights belong to original authors. Visit the link for more info

This Episode: When Computer Music was Experimental, 1951-1971 Early Recordings of Computer Synthesis Playlist Tones from Australia, 1951. All produced using the CSIR Mark 1 computer built at the CSIR's radiophysics division in Sydney. Alan Turing's computer music. 1951. Recording made of tones generated by the mainframe computer at the Computing Machine Laboratory in Manchester, England. Snippets of the tunes God Save the Queen, Baa, Baa Black Sheep, and Glenn Miller's swing classic In the Mood. Plus the voices of computer lab members listening to the sound as it was recorded. Original acetate recording from 1951 restored by University of Canterbury composer Jason Long and Prof Jack Copeland. Incidentally, synthesizing music …. Beat Canon (1960) by Dr. J. R. Pierce. From the album Music From Mathematics, Bell Telephone Laboratories. Numerology (1960) by Max Mathews. From the album Music From Mathematics, Bell Telephone Laboratories. Noise Study (1961) by James Tenney, from Music for Mathematics, Bell Labs, 1961 expanded edition. Bicycle Built For Two (Unaccompanied and Accompanied versions) (1963) From the demonstration record Computer Speech - Hee Saw Dhuh Kaet (He Saw The Cat), produced by Bell Laboratories. Computer Cantata, Prologue to Strophe III (1963) by Lejaren Hiller. From the album Computer Music From The University Of Illinois (1963). This work employed direct computer synthesis using an IBM 7094 mainframe computer and the Musicomp programming language. Lyric Variations For Violin And Computer (1965-1968) by J. K. Randall. From the record A Mitzvah For The Dead For Violin And Tape / Lyric Variations For Violin And Computer on Vanguard Records. Permutation of Five Sounds (1967) by Pietro Grossi. From the album GE-115 - Computer Concerto on the Italian General Electric label. Realized at Studio di Fonologia musicale di Firenze (Italy). Distributed in 1967 as a New Year's gift by Olivetti company. Mixed Paganini (1967) by Pietro Grossi, also from the album GE-115. HPSCHD by John Cage and Lejaren Hiller (1967-1969). The piece was written for Harpsichords and Computer-Generated Sound Tapes. January Tensions (excerpt) by Peter Zinovieff. Computer performed and composed in his private studio outside of London. Synthesism (1970) by Barry Vercoe. From the album Computer Music released on Nonesuch. Realized in the Computer Centers of Columbia and Princeton Universities using MUSIC 360 for the IBM 360 mainframe computer. Vercoe authored this musical programming language. Wishful Thinking About Winter (1970) by Wayne Slawson. From the album Voice of the Computer: New Musical Horizons (1970). Produced at Bell Telephone Laboratories. Eight-Tone Canon (1970) by J.R. Pierce. From the album Voice of the Computer: New Musical Horizons (1970). Produced at Bell Telephone Laboratories. Computer Suite From "Little Boy" (1970) by Jean Claude Risset. From the album Voice of the Computer: New Musical Horizons (1970). Produced at Bell Telephone Laboratories. The Earth's Magnetic Field by Charles Dodge (1971). From Nonesuch Records. Every sound in the piece was computed into digital form using the IBM/ 360 model 91 at the Columbia University Computer Center, and then converted into analog form at the Bell Telephone Laboratories. Computer says farewell, Music from Mathematics (1960).   The Archive Mix in which I play two additional tracks at the same time, to see what happens. Capriccio N. 5 (1967) by Pietro Grossi. From the album GE-115 - Computer Concerto on the Italian General Electric label. Computer synthesized sound. Pitch Variations (1960) by Newman Guttman. From the album Music From Mathematics, Bell Telephone Laboratories. From the album Music From Mathematics, Bell Telephone Laboratories.   Read my book: Electronic and Experimental Music (sixth edition), by Thom Holmes (2020).  

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.01.321828v1?rss=1 Authors: Ekvall, M., Höhle, M., Käll, L. Abstract: Motivation: Permutation tests offer a straight forward framework to assess the significance of differences in sample statistics. A significant advantage of permutation tests are the relatively few assumptions about the distribution of the test statistic are needed, as they rely on the assumption of exchangeability of the group labels. They have great value, as they allow a sensitivity analysis to determine the extent to which the assumed broad sample distribution of the test statistic applies. However, in this situation, permutation tests are rarely applied because the running time of naive implementations is too slow and grows exponentially with the sample size. Nevertheless, continued development in the 1980s introduced dynamic programming algorithms that compute exact permutation tests in polynomial time. Albeit this significant running time reduction, the exact test has not yet become one of the predominant statistical tests for medium sample size. Here, we propose a computational parallelization of one such dynamic programming-based permutation test, the Green algorithm, which makes the permutation test more attractive. Results: Parallelization of the Green algorithm was found possible by nontrivial rearrangement of the structure of the algorithm. A speed-up - by orders of magnitude - is achievable by executing the parallelized algorithm on a GPU. We demonstrate that the execution time essentially becomes a non-issue for sample sizes, even as high as hundreds of samples. This improvement makes our method an attractive alternative to, e.g., the widely used asymptotic Mann-Whitney U-test. Availability: In Python 3 code from the GitHub repository https://github.com/statisticalbiotechnology/parallelPermutationTest under an Apache 2.0 license. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.10.285049v1?rss=1 Authors: Weinstein, S. M., Vandekar, S. N., Adebimpe, A., Tapera, T. M., Robert-Fitzgerald, T., Gur, R. C., Gur, R. E., Raznahan, A., Satterthwaite, T. D., Alexander-Bloch, A. F., Shinohara, R. T. Abstract: Many key findings in neuroimaging studies involve similarities between brain maps. While several statistical procedures have been proposed to test correspondence between maps, there remains no consensus on the correct framing of a null hypothesis or a suitable testing approach. We propose a simple yet powerful permutation-based testing procedure for assessing similarities between two modalities using subject-level data. Our proposed method is similar to traditional permutation procedures in that it involves randomly permuting subjects to generate a null distribution. However, it differs from other recently proposed methods that have involved spherical rotations of the cortical surface or spatial autocorrelation-preserving ''surrogate'' maps of the brain, which depend on strong and potentially unrealistic statistical assumptions. To address these issues, we first demonstrate in simulated data that our method is conservative in terms of type I error and has high power. Next, we illustrate that our method performs well for assessing intermodal relationships from multimodal magnetic resonance imaging data from the Philadelphia Neurodevelopmental Cohort. The proposed test rejects the null hypothesis for modalities for which there is known interdependence in structure (cortical thickness and sulcal depth) but not in cases where an association would not be predicted biologically (cortical thickness and activation on the n-back working memory task). In contrast to previous methods, our approach does not depend on strong statistical assumptions other than the independence of subjects. Notably, our method is the most flexible for analyzing intermodal correspondence within subregions of the brain and has the greatest potential to be used for generalizable statistical inference. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.28.272476v1?rss=1 Authors: Chen, N.-X., Fu, G., Chen, X., Li, L., Milham, M. P., Lui, S., Yan, C.-G. Abstract: Structural and functional neuroimaging have been widely used to track and predict demographic and clinical variables, including treatment outcomes. However, it is often difficult to directly establish and compare the respective weights and contributions of brain structure and function in prediction studies. The present study aimed to directly investigate respective roles of brain structural and functional indices, along with their contributions in the prediction of demographic variables (age/sex) and clinical changes of schizophrenia patients. The present study enrolled 492 healthy people from Southwest University Adult Lifespan Dataset (SALD) for demographic variables analysis and 42 patients with schizophrenia from West China Hospital for treatment analysis. We conducted a model fit test with two variables (one voxel-based structural metric and another voxel-based functional metric) and then performed a variance partitioning on the voxels that can be predicted sufficiently. Permutation tests were applied to compare the contribution difference between each pair of structural and functional measurements. We found that voxel-based structural indices had stronger predictive value for age and sex, while voxel-based functional metrics showed stronger predictive value for treatment. Therefore, through variance partitioning, we could clearly and directly explore and compare the voxel-based structural and functional indices on particular variables. In sum, for long-term change variable (age) and constant biological feature (sex), the voxel-based structural metrics would contribute more than voxel-based functional metrics; but for short-term change variable (schizophrenia treatment), the functional metrics could contribute more. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.02.232710v1?rss=1 Authors: Farine, D. R., Carter, G. G. Abstract: Generating insights about a null hypothesis requires not only a good dataset, but also statistical tests that are reliable and actually address the null hypothesis of interest. Recent studies have found that permutation tests, which are widely used to test hypotheses when working with animal social network data, can suffer from high rates of type I error (false positives) and type II error (false negatives). Here, we first outline why pre-network and node permutation tests have elevated type I and II error rates. We then propose a new procedure, the double permutation test, that addresses some of the limitations of existing approaches by combining pre-network and node permutations. We conduct a range of simulations, allowing us to estimate error rates under different scenarios, including errors caused by confounding effects of social or non-social structure in the raw data. We show that double permutation tests avoid elevated type I errors, while remaining sufficiently sensitive to avoid elevated type II errors. By contrast, the existing solutions we tested, including node permutations, pre-network permutations, and regression models with control variables, all exhibit elevated errors under at least one set of simulated conditions. Type I error rates from double permutation remain close to 5% in the same scenarios where type I error rates from pre-network permutation tests exceed 30%. The double permutation test provides a potential solution to issues arising from elevated type I and type II error rates when testing hypotheses with social network data. We also discuss other approaches, including restricted node permutations, testing multiple null hypotheses, and splitting large datasets to generate replicated networks, that can strengthen our ability to make robust inferences. Finally, we highlight ways that uncertainty can be explicitly considered during the analysis using permutation-based or Bayesian methods. Copy rights belong to original authors. Visit the link for more info

Permutation is a noun that means ‘a major change.’ The Latin word permutare (per myoo TAR ay) means ‘to change thoroughly.’ Our word of the day has changed only slightly after being imported into English and retained the same basic meaning. It may help to think of a permutation as a mutation that significantly alters the thing it changes. When Donna said she’d give me a haircut that would change my life, I was expecting a dramatic new style. But instead of the permutation I was expecting, I wound up with a look that wasn’t that different than the one I had before.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.06.137976v1?rss=1 Authors: Westbrook, A., Ghosh, A., van den Bosch, R., Cools, R. Abstract: Striatal dopamine has been implicated in social behavior across humans, rodents, and non-human primates in artificial laboratory settings with highly-practiced tasks and fixed reward contingencies. Whether striatal dopamine drives naturalistic, spontaneous social behavior remains unclear. Here, we leverage day-to-day logs of unconstrained smartphone behavior and establish a novel link between smartphone social activity and individual differences in striatal dopamine synthesis capacity using [18F]-DOPA PET in (N=22) healthy adult humans. We find a strong relationship such that a higher proportion of social app interactions correlates with lower dopamine synthesis capacity in the bi-lateral putamen. Permutation tests and penalized regressions provide evidence that this link between dopamine synthesis capacity and social versus non-social smartphone taps is specific. These observations provide a key empirical grounding for current speculations about dopamine's role in digital social behavior. Copy rights belong to original authors. Visit the link for more info

Welcome to Radio64, Video Game Music Remix Radio! Hosted by duskvstweak Find many of these songs at ocremix.org/ Find past episodes at youtube.com/duskvstweak Listen live Monday, 6:00pm @ www.wraq.org/index.html 0:03 Mega Man X "Kuwanga Banga" PirateCrab 6:28 SimCity 2000 "SimFunkadelic" Dr. Velvet, HALO_ZERO 10:48 Zelda II: The Adventure of Link "Battle of the Hylian Hero" Random Hero 17:54 Donkey Kong Country "Permutation" Entheogen, injury, Nicole Adams 24:56 Pokémon Red Version "TEEM.ROKIT" Tweex 32:14 Wild Arms "What's Left" Radiowar 37:55 Super Meat Boy "Power of the Meat" Josh Whelchel, Melinda Hershey 44:41 Star Fox 2 "The Lost Legend of Lylat" DS 49:59 Final Fantasy VII "Adrenalyne Kyck" Big Giant Circles, Liontamer, zircon 55:54 Super Mario World "Super Mario Western Show" Hyadain

Dr. Julia Schaletzky explains why the U.S. is having a hard time testing everyone for the coronavirus. Plus: learn about how ketamine can help with depression and anxiety; and how an anonymous Anime fan on 4chan helped solve a 25-year-old math puzzle. Additional resources from Dr. Julia Schaletzky, Executive Director of the Henry Wheeler Center for Emerging and Neglected Diseases at University of California, Berkeley: Center for Emerging and Neglected Diseases (CEND) http://cend.globalhealth.berkeley.edu/ CEND COVID-19 Outbreak Watch http://cend.globalhealth.berkeley.edu/coronavirus-outbreak-watch/ Immunotherapy and Vaccine Research Institute (IVRI) https://ivri.berkeley.edu/ Department of Molecular & Cell Biology (MCB) faculty bio for Julia Schaletzky, PhD https://haas.berkeley.edu/biology-business/academics/faculty/ Follow @CENDUCBerkeley on Twitter https://twitter.com/CENDUCBerkeley Follow  Dr. Schaletzky’s CEND profile http://cend.globalhealth.berkeley.edu/julia-schaletzky-phd/ How can ketamine treat anxiety? by Ashley Hamer (Listener question from Brock in Utah) Chen, J. (2019, March 21). How New Ketamine Drug Helps with Depression. Yale Medicine; YaleMedicine.org. https://www.yalemedicine.org/stories/ketamine-depression/   Meisner, R. C. (2019, May 22). Ketamine for major depression: New tool, new questions - Harvard Health Blog. Harvard Health Blog. https://www.health.harvard.edu/blog/ketamine-for-major-depression-new-tool-new-questions-2019052216673   U.S. Department of Justice Drug Enforcement Administration (2017). Ketamine. In Drugs of Abuse: A DEA Resource Guide. (pp. 68.) https://www.dea.gov/sites/default/files/sites/getsmartaboutdrugs.com/files/publications/DoA_2017Ed_Updated_6.16.17.pdf#page=68  Gao, M., Rejaei, D., & Liu, H. (2016). Ketamine use in current clinical practice. Acta Pharmacologica Sinica, 37(7), 865–872. https://doi.org/10.1038/aps.2016.5   Ketamine vs. Esketamine for Depression. (2019). Psychology Today. https://www.psychologytoday.com/us/blog/two-takes-depression/201904/ketamine-vs-esketamine-depression   Office of the Commissioner. (2019). Understanding Unapproved Use of Approved Drugs “Off Label.” U.S. Food and Drug Administration. https://www.fda.gov/patients/learn-about-expanded-access-and-other-treatment-options/understanding-unapproved-use-approved-drugs-label   Makin, S. (2019, April 12). Behind the Buzz: How Ketamine Changes the Depressed Patient’s Brain. Scientific American. https://www.scientificamerican.com/article/behind-the-buzz-how-ketamine-changes-the-depressed-patients-brain/   An anonymous 4chan post helped solve a 25-year-old math puzzle by Grant Currin Sci-Fi Writer Greg Egan and Anonymous Math Whiz Advance Permutation Problem | Quanta Magazine. (2018). Quanta Magazine. https://www.quantamagazine.org/sci-fi-writer-greg-egan-and-anonymous-math-whiz-advance-permutation-problem-20181105/  Superpermutations — Greg Egan. (2018). Gregegan.Net. http://www.gregegan.net/SCIENCE/Superpermutations/Superpermutations.html  Anonymous 4chan Poster, Houston, R., Pantone, J., Vatter, V. (2018). A lower bound on the length of the shortest superpattern. Posted online. https://oeis.org/A180632/a180632.pdf Subscribe to Curiosity Daily to learn something new every day with Cody Gough and Ashley Hamer. You can also listen to our podcast as part of your Alexa Flash Briefing; Amazon smart speakers users, click/tap “enable” here: https://curiosity.im/podcast-flash-briefing

Neste episódio compartilho o que aprendi lendo a documentação do Scikit-learn sobre partial dependence plots e permutation importances. Se você quiser aprender a habilidade mais importante para trabalhar com Data Science, acesse http://CursoDeDataScience.com Juntei todas as minhas dicas de machine learning num e-book. Conheça http://www.ManualDeDataScience.com Me siga no Instagram e receba dicas exclusivas: http://www.instagram.com/mariofilhoml

In today's pod I'm joined by @RugbyKino and we walk our way through Round 6 of the Heineken Champions Cup to pick out the key matches and work out how we think the final eight will shape up. During the course of our chat I'll mention a chart he sent to me outlining all the different permutations possible at the weekend (and I mean ALL) so if you'd like me to send you a copy give me a shout at paganoblog@gmail.com and I'll be more than happy to send it on. --- Send in a voice message: https://podcasters.spotify.com/pod/show/harpinonrugby/message

Guest host Giselle joins us to talk about the birth of her baby, his time in the NICU, and the post-partum depression that she dealt with after he got home.

Die Fakultät kann auch rekursiv definiert werden, womit man eine mathematisch exaktere Definition erhält. Dieses Video erklärt dir, wie diese rekursive Definition funktioniert. Das Video steht unter CC-BY-SA 4.0.

Die Fakultät ist ein wichtiger Begriff der Kombinatorik, da mit ihr die Anzahl aller Anordnungen einer endlichen Menge bestimmt werden kann. In diesem Video erkläre ich dir die Fakultät, seine Definition und einige Beispiele. Dieses Video steht unter CC-BY-SA 4.0.

Hanouka, la permutation (06-12-19) by Rav Avraham IFRAH

Tasting 49 concludes our Massachusetts series with a bang. Trillium Brewing Company out of Boston was one of our most anticipated shows when we heard we'd be getting some goods from The Bay State. Give it a listen and see if it lived up to our expectations. Beer Line-up: Melcher Street (IPA), Vicinity (Double IPA), Morph (India Pale Ale), Fated Farmer Series: Red Currant (Barrel Fermented Wild Ale), Permutation 6.37 (Sour Ale with Orange Peel, Passionfruit, Guava, Vanilla, and Lactose), and Fated Farmer Series: Blueberry (Barrel Fermented Wild Ale). Local Spotlight was the Rented Tux Vanilla Porter from Thirsty Eye. We also tried their recommended Thirsty Eye version as well, which was a combination of that porter and their cold brew.   Break music is a little Phil Collins action. Intro and Exit Music provided by bensound.com

Tech Paf, c'est l'émission d'exploration du futur tel que le monde de la tech nous promet. Chaque semaine Marie Misset aborde une mutation en cours, en vous donnant des nouvelles des foufous de la… See acast.com/privacy for privacy and opt-out information.

J-Hotz, AKA Jordan Dixon-Hamilton, AKA Patriot J, AKA etc... is a young man with a very bright future. Between law school, making music, developing an online presence and multiple digital income streams, J has a lot going on, and he seems to be doing it with ease and style. We talked about the nature of the law, narrative, pattern recognition, collectivism vs individualism and a lot more. For a dude not even in his mid-twenties, Jordan has an impressive depth of knowledge and a good sense of the world. In this conversation, I play the perplexed old man with occasional insights and J-Hotz plays the hip youngster well-versed in the modern means and methods. It was a good chance for me to understand the perspectives of the "Always Had Internet and 9/11" crowd a little better, and I restrained myself from yelling at him to get off my lawn. Tune in for a very insightful conversation with a very promising young man. Want more from Jordan? Website Twitter Spotify Apple Music --- Send in a voice message: https://anchor.fm/logocentrifugal/message Support this podcast: https://anchor.fm/logocentrifugal/support

Best wishes and warm greetings to you and may God shower you with all the great things that you deserve, for He is risen! Yet another Easter Weekend... I'v'Put together something to ease people up on the roads, holidays ...etc... You will definitely love it, just volume up, cheer up, & dance !! Ladies & Gentleman I have put a tape 3 years ago called "Jazz'd Permutation" and today I present to you the "Reloaded" version ,,,, (Jazz'd Permutation Reloaded) Keep in Mind ........ :) “The piano ain't got no wrong notes.” ― Thelonious Monk "...lets deep deeper..."

Best wishes and warm greetings to you and may God shower you with all the great things that you deserve, for He is risen! Yet another Easter Weekend... I'v'Put together something to ease people up on the roads, holidays ...etc... You will definitely love it, just volume up, cheer up, & dance !! Ladies & Gentleman I have put a tape 3 years ago called "Jazz'd Permutation" and today I present to you the "Reloaded" version ,,,, (Jazz'd Permutation Reloaded) Keep in Mind ........ :) “The piano ain't got no wrong notes.” ― Thelonious Monk "...lets deep deeper..."

Best wishes and warm greetings to you and may God shower you with all the great things that you deserve, for He is risen! Yet another Easter Weekend... I'v'Put together something to ease people up on the roads, holidays ...etc... You will definitely love it, just volume up, cheer up, & dance !! Ladies & Gentleman I have put a tape 3 years ago called "Jazz'd Permutation" and today I present to you the "Reloaded" version ,,,, (Jazz'd Permutation Reloaded) Keep in Mind ........ :) “The piano ain't got no wrong notes.” ― Thelonious Monk "...lets deep deeper..."

Podcast 38: The Yearly Re-cap We do a year in review! (Shocker!) Everyone go check their untappd year in review and follow along with us! Dog friends Hercules and Jackson join us by destroying dog toys! Beer #1: Brut IPA - New Belgium (6.8% Brut *duh* IPA) Alex said the beer guy at Liberty beer said this was very forgettable. Very light body and seems under carbonated for the style. We talked about all our New Year celebrations. Alex had a rowdy time. Alex made some calculations about how much we all spent at Dancing Gnome this year (Hint: it's more than we would all like to admit) and our favorite beer people. Our first segment was about beer trends in 2018. - Sours were up first - Hazy IPAs were the top dog for sure - Milkshake IPAs Beer #2: Sparkler - Sixpoint (7% Brut IPA) Pours very cloudy but definitely has a lighter color and a lot of carbonation. Ryan discussed his favorite beers/breweries from his travels this year. Noble Creature was one of his highlights in Youngstown, OH. Alex had some fun in Cleveland this year. We all appreciate his discovery of Platform beer. Ryan recounted his trip to Jacksonville and how impressed he was with everyone in the chain restaurants having local state beers on tap. We explore the idea of online reviews and how much weight they carry in choosing your nightspot or food or whatever else. Segment 2: Favorite beers of the year! Sara: Underscore Passionfruit (Dancing Gnome), Stackhouse Imperial Stout (Charles Towne Fermentory), Permutation #52 (Trillium) Nick: Blueberry Cobbler J.R.E.A.M. (Burley Oak), Gnome's Soul (Barreled Souls/Dancing Gnome), Permutation #52 (Trillium) Ryan: dodged the question and said he liked can designs. Alex: Toucan Slam (Strange Roots), 3 Scoops Passionfruit/Lemonade/Mango (The Answer) Jake: Permutation #52 (Trillium), Very Green (Treehouse) Least Favorite beers: Sara: Mike (Magnify/DG collab) Alex: Lemon Ginger Saison (Platform) Nick: Gorilla Snacks (Burley Oak) Ryan: Nothing particular but he's not a fan of Christmas beers. Jake: His own homebrew was the worst, Backlash beers were very underwhelming, We covered the beer festivals we went to and the good/bad/ugly that came with them. From there we launch into some of the cool bars we visited this year. Segment 3: Podcast Trends Hairwatch 2018 - The story of one man's hair control or lack thereof Catchphrases - “Hello, and welcome!” Merch in 2019 - we're speaking this into existence Memes were fire this year. We hated some words this year Everyone chimes in on our love of Hitchhiker brewery and we're really excited to see what they bring in the new year. Our opinions were very mixed on them and we discuss our thoughts on what they should do. Dancing Gnome was up next on the roast. Some people think they need to sit on their beers a little longer. IPAs need to be fresh, but letting some DG beers sit in your fridge for a week allows it to develop differently. Jake joined us for the end of the cast, and even with good service his service still sucked. Segment 4: Looking forward - 2019 beer trends, festivals, guests and things Travel: Alex wants to get to Bend, OR, Columbus, OH, Ryan is going to Breckenridge, CO Dancing Gnome's Bird series (replacing the Flower series), Dead Sleep, Underscore and Black Clouds. Beer Fests: FreshFest, Dancing Gnome birthday party, Juicy Brews Late Night (Cinderlands/Hop Culture) Upcoming events - Nugget Nectar release this week! Grist House is opening a new location! Check their social media to get the scoop! Let's Get Munsoned - Breaking Brews No-Tap Bowling tournament 2/9/19 The wrap-up: Alex came out to Ryan first and then Nick and Sara which made for a good story. We all really enjoy putting this podcast on and really appreciate our newfound friends and cool people who interact with us. Thank you to everyone who listens to us and we hope you enjoy us as much as we enjoy all of you. Thank you all and cheers to great beers in 2019!

DECENTRALIZED RADIO: DCTVWe believe in an exciting and inevitable future where everything that we do will be fundamentally touched and transformed by blockchain technology and the world will be an infinitely better place to live, work, and play.Consequently, our mission is to accelerate the growth of blockchain within the public conscience, vernacular, and culture through awareness, education, and entertainment.In fact, our first explicit milestone is to get 1,000,000 new folks into blockchain, bitcoin, and cryptocurrency! This is just the first of many steps!If this resonates with you then join us; you are the vanguard.Subscribe on YouTube - https://www.youtube.com/channel/UCueLJ4vLHTwMpYILmdBjRlgFollow on Twitter - https://twitter.com/decentralizedtvFollow on Google + - https://plus.google.com/+DecentralizedTVOriginal Articles on Medium - https://medium.com/decentralizedtvEmail List - https://mailchi.mp/fa9de7339b0c/decentralized-newsSupport Decentralized TV original projects!Crypto Social Exchange - https://yen.io/The Bitcoin Pub - https://thebitcoin.pub/Crypto News - https://cryptoyum.com/Coin Prices and More - https://coinpuffs.com/Learn the Fundamentals of Bitcoin - https://10daysofbitcoin.com/Follow the best podcasts from the best minds in the Bitcoin and Cryptocurrency space on twitter.https://twitter.com/bitcoinpodcasts

NEWBD is back for a second year and Ben and Mo kick of season 2 with some happenings in local beer. They cover the meaning of the Permutation series from Trillium, some 2018 Goose Island variants, recap season 1 and talk about the We're Funked Fest and Newport Craft Beer Race coming up. Enjoy!!

Episode 164 of The Independent Characters is late. Super late in fact. Let us explain: As you will hear in this episode we have an interview with Steel Wool - a video game company working on a great new game for Warhammer 40k. Unfortunately, we also talked a lot about this interview and its contents. Their announcement was subsequently delayed due to… reasons. As a result, we could not release the episode or even just remove the interview and release it on time, and in fact released it out of order (Episode 165 dropped a few days ago). We apologize for the delay and we have learned our lesson to never again tie an episode to a PR Announcement of a release! So with that out of the way, let's talk about what this episode actually contains! First we have a fairly long and meandering Hobby Progress discussion which also weighs in on a few new announcements from GW and other thoughts and ideas about the community. We then move into our (delayed) interview with Steel Wool about their new Betrayal at Calth video game! Trust us when we tell you that this thing is VERY cool. Listen to the interview and you will see why. We then have an interview with returning guests Kat and Caleb of CK Studios. They have some amazing events coming up and we get some insight into what they have going on. Last but certainly not least, we have a short discussion about our home campaign The Permutation of Arasys, which we have been playing through. We talk about the structure of the campaign, how it is going so far, and what our expectations are going forward. Again we apologize for the delays in releasing the show, but we really hope you enjoy what we have for you. Time Stamps: 0:00:00 - Show Intro and Host Introduction 0:07:15 - Workbench and Hobby Progress 1:04:15 - Steel Wool Interview 1:45:45 - CK Studios Interview 2:34:40 - The Permutation of Arasys Campaign 2:59:00 - Final Thoughts and Show Closing Relevant Links: KR Multicase - SPONSOR Tablewar! - SPONSOR Wargamma - SPONSOR Forge World Games Workshop The Black Library The Permutation of Arasys Campaign Files Betrayal at Calth Website Steam Page for Betrayal at Calth

Episode 164 of The Independent Characters is late. Super late in fact. Let us explain: As you will hear in this episode we have an interview with Steel Wool - a video game company working on a great new game for Warhammer 40k. Unfortunately, we also talked a lot about this interview and its contents. Their announcement was subsequently delayed due to… reasons. As a result, we could not release the episode or even just remove the interview and release it on time, and in fact released it out of order (Episode 165 dropped a few days ago). We apologize for the delay and we have learned our lesson to never again tie an episode to a PR Announcement of a release! So with that out of the way, let’s talk about what this episode actually contains! First we have a fairly long and meandering Hobby Progress discussion which also weighs in on a few new announcements from GW and other thoughts and ideas about the community. We then move into our (delayed) interview with Steel Wool about their new Betrayal at Calth video game! Trust us when we tell you that this thing is VERY cool. Listen to the interview and you will see why. We then have an interview with returning guests Kat and Caleb of CK Studios. They have some amazing events coming up and we get some insight into what they have going on. Last but certainly not least, we have a short discussion about our home campaign The Permutation of Arasys, which we have been playing through. We talk about the structure of the campaign, how it is going so far, and what our expectations are going forward. Again we apologize for the delays in releasing the show, but we really hope you enjoy what we have for you. Time Stamps: 0:00:00 - Show Intro and Host Introduction 0:07:15 - Workbench and Hobby Progress 1:04:15 - Steel Wool Interview 1:45:45 - CK Studios Interview 2:34:40 - The Permutation of Arasys Campaign 2:59:00 - Final Thoughts and Show Closing Relevant Links: KR Multicase - SPONSOR Tablewar! - SPONSOR Wargamma - SPONSOR Forge World Games Workshop The Black Library The Permutation of Arasys Campaign Files Betrayal at Calth Website Steam Page for Betrayal at Calth

Background: Genome wide association studies (GWAS) are applied to identify genetic loci, which are associated with complex traits and human diseases. Analogous to the evolution of gene expression analyses, pathway analyses have emerged as important tools to uncover functional networks of genome-wide association data. Usually, pathway analyses combine statistical methods with a priori available biological knowledge. To determine significance thresholds for associated pathways, correction for multiple testing and over-representation permutation testing is applied. Results: We systematically investigated the impact of three different permutation test approaches for over-representation analysis to detect false positive pathway candidates and evaluate them on genome-wide association data of Dilated Cardiomyopathy (DCM) and Ulcerative Colitis (UC). Our results provide evidence that the gold standard - permuting the case-control status - effectively improves specificity of GWAS pathway analysis. Although permutation of SNPs does not maintain linkage disequilibrium (LD), these permutations represent an alternative for GWAS data when case-control permutations are not possible. Gene permutations, however, did not add significantly to the specificity. Finally, we provide estimates on the required number of permutations for the investigated approaches. Conclusions: To discover potential false positive functional pathway candidates and to support the results from standard statistical tests such as the Hypergeometric test, permutation tests of case control data should be carried out. The most reasonable alternative was case-control permutation, if this is not possible, SNP permutations may be carried out. Our study also demonstrates that significance values converge rapidly with an increasing number of permutations. By applying the described statistical framework we were able to discover axon guidance, focal adhesion and calcium signaling as important DCM-related pathways and Intestinal immune network for IgA production as most significant UC pathway.

We discuss two-sample global permutation tests for sets of multivariate ordinal data in possibly high-dimensional setups, motivated by the analysis of data collected by means of the World Health Organisation's International Classification of Functioning, Disability and Health. The tests do not require any modelling of the multivariate dependence structure. Specifically, we consider testing for marginal inhomogeneity and direction-independent marginal order. Max-T test statistics are known to lead to good power against alternatives with few strong individual effects. We propose test statistics that can be seen as their counterparts for alternatives with many weak individual effects. Permutation tests are valid only if the two multivariate distributions are identical under the null hypothesis. By means of simulations, we examine the practical impact of violations of this exchangeability condition. Our simulations suggest that theoretically invalid permutation tests can still be 'practically valid'. In particular, they suggest that the degree of the permutation procedure's failure may be considered as a function of the difference in group-specific covariance matrices, the proportion between group sizes, the number of variables in the set, the test statistic used, and the number of levels per variable.

Welcome to YIP Snip! This week's topic is Improv! (Pre apology for Mary being sick this week!)Download YIP Snip Ep 5Or Listen Here: In This Episode: YIP on FacebookTed Talk Video that started this whole discussion!Thanks again Sara Arrell! Nadira Jamal ClassesLet me Google that for you!Hipmix about Improv Princess Farhana Blog about ImprovBackground Music:Artist: Amon Tobin -Amazon or Albums: Permutation & SupermodifiedSongs: Sordid, Nightlife, People like Frank, Sultan Drops, Slowly, Chocolate Lovely, Keepin' it Steel (The Anvil)

Background: The random forest (RF) method is a commonly used tool for classification with high dimensional data as well as for ranking candidate predictors based on the so-called random forest variable importance measures (VIMs). However the classification performance of RF is known to be suboptimal in case of strongly unbalanced data, i.e. data where response class sizes differ considerably. Suggestions were made to obtain better classification performance based either on sampling procedures or on cost sensitivity analyses. However to our knowledge the performance of the VIMs has not yet been examined in the case of unbalanced response classes. In this paper we explore the performance of the permutation VIM for unbalanced data settings and introduce an alternative permutation VIM based on the area under the curve (AUC) that is expected to be more robust towards class imbalance. Results: We investigated the performance of the standard permutation VIM and of our novel AUC-based permutation VIM for different class imbalance levels using simulated data and real data. The results suggest that the new AUC-based permutation VIM outperforms the standard permutation VIM for unbalanced data settings while both permutation VIMs have equal performance for balanced data settings. Conclusions: The standard permutation VIM loses its ability to discriminate between associated predictors and predictors not associated with the response for increasing class imbalance. It is outperformed by our new AUC-based permutation VIM for unbalanced data settings, while the performance of both VIMs is very similar in the case of balanced classes. The new AUC-based VIM is implemented in the R package party for the unbiased RF variant based on conditional inference trees. The codes implementing our study are available from the companion website: http://www.ibe.med.uni-muenchen.de/organisation/mitarbeiter/070_drittmi ttel/janitza/index.html.

Geek culture from a men's rights/red pill perspective. Special guest host: Wooly Bumblebee and xxToyedxx!! Show notes: http://www.avoiceformen.com/a-voice-for-men/tfi-attack-of-the-killer-attention-whores/ Topics include Fallout 3 and Fallout New Vegas, Anita Sarkeesian and other attention whores in the gaming industry such as Frag Dolls, Truth and Oblivion comics, Who Needs Feminism, Michael Coren, Michael Calleri, Violent abusive stalinist thugs, Suzanne Venker and the War on Men, Permutation of Ninjas, women are not always the gentler sex, Girl Writes What, White Knights, and more!

Harvey, JA (University of Chicago) Friday 27 January 2012, 14:00-15:00

Harvey, JA (University of Chicago) Thursday 26 January 2012, 14:00-15:00

Harvey, JA (University of Chicago) Friday 27 January 2012, 12:00-13:00

Lecture 5: Gusfield lectures about counting the number of inversions in a permutation. He introduces fast integer multiplication by divide and conquer.

In Lecture 4, students learn about solving a more complex recurrence relation by unwrapping. Gusfield also addresses the problem of counting inversions in a permutation.

Grade 11

Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observed. Recent works on permutation-based variable importance measures (VIMs) used in RF have come to apparently contradictory conclusions. We present an extended simulation study to synthesize results. Results: In the case when both predictor correlation was present and predictors were associated with the outcome (H(A)), the unconditional RF VIM attributed a higher share of importance to correlated predictors, while under the null hypothesis that no predictors are associated with the outcome (H(0)) the unconditional RF VIM was unbiased. Conditional VIMs showed a decrease in VIM values for correlated predictors versus the unconditional VIMs under H(A) and was unbiased under H(0). Scaled VIMs were clearly biased under H(A) and H(0). Conclusions: Unconditional unscaled VIMs are a computationally tractable choice for large datasets and are unbiased under the null hypothesis. Whether the observed increased VIMs for correlated predictors may be considered a "bias" - because they do not directly reflect the coefficients in the generating model - or if it is a beneficial attribute of these VIMs is dependent on the application. For example, in genetic association studies, where correlation between markers may help to localize the functionally relevant variant, the increased importance of correlated predictors may be an advantage. On the other hand, we show examples where this increased importance may result in spurious signals.