Podcasts about LAD

Play Episode Listen Later Oct 3, 2021 43:06

Quelques infos supplémentaires sur l'actualité de la santé mentale :Le numéro national de prévention du suicide a été lancé le vendredi 5 octobre 2021, annonce Olivier Véran. "Gratuit, accessible 7 jours sur 7 et 24h/24, depuis tout le territoire national, ce numéro permettra d'apporter une réponse immédiate aux personnes en détresse psychique et à risque suicidaire", a précisé le ministre.À partir de 2022, les séances chez un psychologue en ville seront donc remboursées. Le montant de la première consultation sera fixé à 40 euros, les autres à 30 euros. Il n'y aura aucun reste à charge pour les patients.Mercredi 29 novembre, le tribunal de Los Angeles a décidé de retirer la tutelle de Britney Spears à son père Jamie dont il abuse depuis 2008.Depuis peu, des célébrités telles que Britney Spears, Simone Biles, Billie Eilish et bien d'autres, tentent d'alerter les médias et le public sur l'importance de la santé mentale. Pression musicale, sportive ou médiatique, ces stars se sentent-elles enfin libérées ? Quels obstacles doivent-elles encore surmonter aujourd'hui ? Clémentine Gallot et Kaoutar Harchi nous exposent les dessous de ce sujet peu traité par les médias mainstream dans ce nouvel épisode de Quoi de Meuf. Les références entendues dans cet épisode : I May Destroy You de Michaela Coel (2020)“Les Français face à la vague psy du Covid-19”, La Dépêche (2021)Team USA : Scandale dans le monde de la gymnastique de Bonni Cohen et Jon Shenk (2020)Liye Fu and Cristian Danescu-Niculescu-Mizil and Lillian Lee Cornell University, “Tie-breaker: Using language models to quantify gender bias in sports journalism” (2016)Framing Britney Spears de Samantha Stark (2021)#MonPostPartum porté par Illana Weizman, Ayla Saura, Morgane Koresh et Masha Sacré. Illana Weizman, “Ceci est notre post-partum. Défaire les mythes et les tabous pour s'émanciper”, Marabout (2021)Paul B. Preciado, “Je suis un monstre qui vous parle”, Grasset (2020)Week-end, “Les thérapies en ligne: la révolution du self-care ?” (2021)Les comptes Instagram qui parlent de santé mentale : @freud.intensifies ; @millennial.therapist ; @lapsydufutur ; @anxietyjoshAudrey Chabal, “Instagram : le nouveau divan des psys”, Elle (2021)Virginie Ollagnier, “Nellie Bly”, Glénat (2021)Le bal des folles de Mélanie Laurent (2021)En thérapie de Eric Toledano et Olivier Nakache (2021)Fleabag de Phoebe Waller-Bridge (2016)Girls de Lena Dunham (2012)Crazy ex-girlfriend de Rachel Bloom et Aline Brosh McKenna (2015)Euphoria de Ron Leshem, Daphna Levin et Tmira Yardeni (2019)This way up de Aisling Bea (2019)L'album Happier than ever de Billie Eilish (2021)Jean-Victor Blanc, “Pop & Psy”, Plon (2019)Le podcast Mad Chat de Sandy Allen (2019)Scenes from a marriage de Hagai Levi (2021)Mona Chollet, “Réinventer l'amour. Comment le patriarcat sabote les relations hétérosexuelles”, La Découverte (2021)Quoi de Meuf est une émission de Nouvelles Écoutes. Rédaction en chef : Clémentine Gallot. Journalistes chroniqueuses : Emeline Amétis, Kaoutar Harchi, Anne-Laure Pineau, Pauline Verduzier. Montage et mixage par Laurie Galligani. Prise de son par Adrien Beccaria à l'Arrière Boutique. Générique réalisé par Aurore Meyer Mahieu. Réalisation et coordination : Cassandra de Carvalho et Mathilde JoninSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Circulation September 28, 2021 Issue

Circulation on the Run

Play Episode Listen Later Sep 27, 2021 29:39

This week's episode features a panel discussion. Please join author Harmony Reynolds, editorialist David Newby, and Associate Editors Nicholas Mills and Sandeep Das as they discuss the articles "Natural History of Patients with Ischemia and No Obstructive Coronary Artery Disease: The CIAO-ISCHEMIA Study, "Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity," and editorial "Forget ischemia, it's all about the plaque." Dr. Greg Hundley: Welcome listeners to this week's, September 28th, issue of Circulation on the Run. And I'm Dr. Greg Hundley, Director of the Poly Heart Center at VCU Health in Richmond, Virginia, and associate editor at Circulation. And this week, listeners, we have an outstanding feature discussion. It's actually forum where we're going to discuss from Dr. Reynolds two papers pertaining to the ischemia trial. One looking really at the functional importance of stress testing, the other looking at the anatomical importance of cardiac CT scanning. We're going to have two of the associate editors along with Dr. Reynolds, each that handled the two papers and also a guest editorialist that will help put the entire paper together. Well, before we get to that, we're going to start and review some of the other papers in this issue. And let's grab a cup of coffee and get started. Dr. Greg Hundley: The first comes to us from Dr. Maliheh Nazari-Jahantigh from Ludwig Maximilian University in Munich, Germany, and it pertains to atherosclerotic plaque rupture. So the necrotic core of an atherosclerotic plaque is partly formed by ineffective efferocytosis, which increases the risk of an atherosclerotic plaque rupture. And in cell biology, efferocytosis comes from the Latin word effero, which means to take to the grave or to bury. And it's really the process by which apoptotic cells are removed by phagocytic cells. And so therefore, it can be regarded as the burying of "dead cells." Now MicroRNAs contribute to necrotic core formation by regulating efferocytosis as well as macrophage apoptosis. We also know that atherosclerotic plaque rupture occurs at an increased frequency in the early morning, indicating that diurnal changes occur in plaque vulnerability. Now all those circadian rhythms play a role in atherosclerosis, the molecular clock output pathways that control plaque composition and rupture susceptibility are unclear. Dr. Greg Hundley: And so these authors investigated this phenomenon. And what they found, interestingly, their results suggest that the molecular clock in atherosclerotic lesions induces a diurnal rhythm of apoptosis regulated by circadian Mer 21 expression in macrophages that is not matched by efferocytosis, and thereby increasing the size of the necrotic core of these plaques. So clinically, the implications are that a macrophage death clock controlled by mer 21 may enhance lesion growth and susceptibility to plaque rupture indicating that the molecular clock can have detrimental effects under pathologic conditions. And additionally, the molecular clock in lesional macrophages may contribute to the circadian pattern of myocardial infarction, which could be a target for preventive measures to limit the mismatch between apoptosis and efferocytosis and thus reduce plaque vulnerability in the early morning. Dr. Greg Hundley: Well, our second paper comes to us also from the world of preclinical science, and it's from Professor Thomas Braun from the Max Planck Institute for heart and lung research. And this particular paper pertains to pulmonary hypertension. And as we know, pulmonary hypertension and chronic obstructive pulmonary disease, or COPD, originate from a complex interplay of environmental factors in genetic predispositions and little is known about developmental abnormalities or epigenetic dysregulation that might predisposed individuals to develop pulmonary hypertension or COPD in adults. So these authors screen a cohort of human pulmonary hypertension in COPD patients for changes of histone modifications by immunofluorescent staining. And also, they developed knockout mouse lines targeting cardiopulmonary progenitor cells and different heart and lung cell types. Dr. Greg Hundley: Now molecular, cellular and biochemical techniques were applied to analyze the function of SUV420H1-dependent epigenetic processes in cardiopulmonary progenitor cells and their derivatives. Well, what did they find? So the investigators found that loss of SUV420H1 in cardiopulmonary progenitor cells caused a COPD-like pulmonary hypertension phenotype in mice, including formation of perivascular tertiary lymphoid tissue, and goblet cell hyperplasia, hyperproliferation of smooth muscle cells and myofibroblast, impaired alveolarization and maturation of defects of the microvasculature leading to massive ripe ventricular dilation and premature death. Dr. Greg Hundley: Now mechanistically SUV420H1 bound directly to the five prime upstream in regulatory element of Superoxide Dismutase 3 gene to repress its expression and increased levels of the extracellular Superoxide Dismutase 3 enzyme in SUV420H1 mutants increased hydrogen peroxide concentration causing vascular defects and impairing alveolarization. So what can we take away, listeners, from this clinically? Well, the author's findings reveal a pivotal role of histone modifier SUV420H1 in cardiopulmonary co-development and uncover developmental origins of cardiopulmonary diseases. And now these results suggest that this study will facilitate the understanding of pathogenic events causing pulmonary hypertension in COPD and aid the development of epigenetic drugs for treatment of other cardiopulmonary diseases. Dr. Greg Hundley: Well, listeners, what else is in, we call it, the mail bag, but some of the other articles in the issue? Well, doctors Varricchi and Wang exchanged letters regarding the prior article, the role of IgE FcεRI in pathological cardiac remodeling and dysfunction. And our own Sara O'Brien highlights articles from our circulation family of journals. Professor Ross has a Research Letter regarding the effects of walnut consumption for two years on lipoprotein subclasses among healthy elders findings from the WAHA randomized controlled trial. And then finally, Dr. Maurer has a really nice On My Mind piece that raises concerns pertaining to the use of cardiac scintigraphy and screening for transthyretin cardiac amyloidosis. And now listeners, we're going to turn to that forum discussion where we have an author, our associate editors and an editorialist discussing two really important papers from the ischemia trial. Dr. Greg Hundley: Well, listeners, we are very excited today to discuss in sort of the forum feature, two papers pertaining to the ischemia trial. And with us this day, we have Dr. Harmony Reynolds from New York University Grossman School of Medicine in New York city; two of our associate editors, Dr. Nick Mills from university of Edinburgh in Scotland; and Dr. Sandeep Das from UT Southwestern; and then also an editorialist, Dr. David Newby, who's also University of Edinburgh in Scotland. Welcome to everyone. Dr. Greg Hundley: Harmony, we're going to start with you. And in the first paper, the natural history of ischemia and no obstructive coronary artery disease, can you describe for us a little bit of the context of what shaped this question for you, what hypothesis did you want to test? And then describe for us a little bit your study population and your study design. Dr. Harmony Reynolds: Sure. Thanks so much for having me here to discuss these papers. I'm really appreciative of the attention from circulation, and I'm excited for this discussion today. So in this first natural history paper, we were looking at ischemia with non-obstructive corona arteries, INOCA, the kind of thing that used to be called cardiac syndrome X. And we know this is an extremely common problem. It's defined by having signs or symptoms of ischemia and no 50% or greater lesion on coronary imaging. And we also know from prior invasive studies that the mechanisms of this are overwhelmingly microvascular coronary disease and provokable coronary spasm. Some patients prove to be normal and invasive testing, but most will have some objective abnormality. Dr. Harmony Reynolds: We know this problem is associated with a higher risk of cardiovascular events and with high costs, but what we didn't know was whether the symptoms and ischemia on stress testing are tracking together in these patients. So if we're trying to treat these patients, should we be doing serial stress testing and targeting the medical therapy to ischemia abrogation or should we just be making their symptoms go away? And would this provide any long range insights for us into when we can figure out the symptom are truly ischemic in nature? Dr. Harmony Reynolds: So we decided to use the ischemia trial, and we had a fantastic platform for that in ischemia because, as you know, patients were screened in part for randomization using coronary CT angiography. And even though these patients had moderate or severe ischemia, some had no obstructive coronary disease on that CT coronary angiogram. And those are the patients that we enrolled in CIAO-ISCHEMIA. They had an assessment of angina at baseline, and they had to be symptomatic at some point. They didn't have to be symptomatic at the moment. They were enrolled in CIAO, but they had their stress test generally to evaluate ischemic symptoms. And they had their stress echocardiogram read by a core lab. Importantly, that core lab did not know the result of that CT scan. So they read them like all the other ischemia stress echoes. And then these patients had an angina and ischemia assessment with a repeat stress echo at one year. Dr. Greg Hundley: And what did you find? Dr. Harmony Reynolds: There were a number of interesting findings from this study. The first thing was that the severity of ischemia in the CIAO patients with INOCA was very similar to the ischemia patients who had obstructive coronary disease. So that tells us that the INOCA problem can happen with quite a lot of ischemia, and that had not been as well delineated before. Another finding expected, but we did find that is that there were many more women in the INOCA group, two thirds of our child population was female. And in ischemia, overall, it was closer to a quarter. We found that the symptoms and the ischemia were quite changeable. So at one year, the stress echocardiogram was normal in half of the child participant and only 23% still had moderate or severe ischemia. Angina had improved in 43%, and it worsened in 14%. There was an awful lot of change over one year, but the change in angina and the change in ischemia did not track together. And that was a bit of a surprise to me. Dr. Greg Hundley: Very nice. Well, Nick, I know serving it as an associate editor, you see many papers come across your desk. What attracted you to pushing this paper forward for publication? Dr. Nicholas Mills: Thanks, Greg, and congratulations. Harmony, we love the papers you've been sending from ischemia trial, which genuinely is changing clinical practice all over the world. And it's been great to see the secondary analysis and follow-up papers. So this paper attracted me because it addresses an area where I still don't fully understand in clinical practice, what recommendations to make for my patients and what tests to arrange. As you say, INOCA is more common in women. I think these patients have largely been understudied over many decades, and there remains a lot of uncertainty. I liked it because you had a core lab, blinded core lab analysis with systematic follow up and it was a really well-done study. It reassured me in many ways because it told me that actually a lot of these patients, their symptoms get better, sort of irrespective of what we do. The treatments didn't seem to track within improvements of symptom, nor did the severity of ischemia, and that I think provides a lot of reassurance to our patients who are in this situation. Dr. Nicholas Mills: Of course, there is a group there who continue to have moderate to severe ischemia a year later. And I think this trial helps us understand maybe how we should study this group more, understand the heterogeneity that you've observed in this population in order to really try and resolve that and resolve their ongoing symptoms. But for the majority, four in five patients, they're going to do well and they're going to get better over time. And I think that's an important message from this study. Dr. Greg Hundley: Thank you so much, Nick. Well, Harmony, we're going to come back to you. You have a second paper, the outcomes in the ischemia trial really based on coronary artery disease and ischemia severity. Can you describe for us, again, working us back through, what were some of the constructs that you really wanted to address here? What was your hypothesis? And again, how did this study population maybe differ a little bit in this second paper? Dr. Harmony Reynolds: Thanks so much. So this paper tracked outcomes based on the severity of ischemia and the severity of coronary artery disease on the CT coronary angiogram now in randomized patients in the ischemia trial. So all of these had obstructive coronary disease and they were selected for randomization. And the premise of the ischemia trial was partly that we would be able to select patients who might benefit from revascularization and from an invasive strategy really based on how much ischemia they had on the stress test. Moderate or severe ischemia was required for randomization and for entry into the trial, but a core lab read those stress tests independently and independently assessed ischemia. And in some cases, when the site thought there was moderate or severe ischemia, the core lab did not agree. And the core lab independently decided whether it was moderate or severe. So we wanted to understand whether the ischemia severity at the time of trial entry influenced outcomes and influenced the outcomes by randomization treatment assignment. Dr. Harmony Reynolds: Similarly, about half of the patient had a CT that was interpretable for the number of vessels disease. And we wanted to understand in the context of all those prior stable ischemic heart disease trials, showing a lot of heterogeneity by the amount of coronary disease, whether in ischemia as well, there would be heterogeneity of the treatment effect based on how much coronary disease you started with. So the ischemia population, and this is almost the entire randomized cohort, but it's important to recognize for the CT analysis that only about three quarters of the patients had CT. They didn't get a CT, if your GFR was too low or if you had known coronary anatomy. And among those Cts, not every CT is perfectly interpretable for the number of vessels disease. These are sicker patients. These are not the super stable patients who have a low prevalence of disease. These were pretty sick, multi-vessel coronary disease patients, and they couldn't always hold their breast all that well. There was a lot of calcification in these. Dr. Harmony Reynolds: So for example, if there was motion artifact in the right coronary artery, we wouldn't be able to quantify the number of vessels disease. And that left us with a cohort of about half of our ischemia population, but that's still a giant cohort of several thousand patients. So that's how our study. Dr. Greg Hundley: Very good. And what did you find here? Dr. Harmony Reynolds: Here, we found that more severe ischemia was not associated with outcomes. Now that does go along with the COURAGE study in which after you adjust for clinical characteristics, ischemia was not associated with outcomes. But still it came as something of a surprise that even severe ischemia was not associated with a higher risk of outcomes than moderate or mild ischemia. We also found that in the coronary disease group, no matter how you measure the severity of coronary disease, the Duke prognostic index, the number of vessels disease, the segment involvement score, the segment stenosis score, all of these measures were very strongly associated with our outcomes, whether it was all cause mortality MI or our composite. Dr. Harmony Reynolds: When it came to treatment effect, we found that the ischemia severity were no relationship to treatment effect. There was no ischemia subgroup in which there appeared to be an advantage with an invasive strategy. But in the coronary disease group, and again taking into account the caveats of not everybody had a CT interpretable for the number of vessels disease, in those with the most severe coronary disease, that's the Duke 6 subgroup. And they had multi-vessel severe disease, either two vessel including the proximal LAD at 70% or three vessels with 70% stenosis. There was no benefit on mortality. But if we looked at the composite endpoint of cardiovascular death or MI, there appeared to be some advantage to the invasive strategy. Dr. Greg Hundley: Very good. Well, Sandeep, similar to Nick, working as an associate editor and meeting weekly, what attracted you to this particular paper? And why did you want to really see it come forward to be published? Dr. Sandeep Das: So first of all, I want to echo Nick's comments that these are great papers, and thanks very much for sending those our way and letting us have sort of first crack at them before they're released to the world. And I also want to comment on the side that Harmony and her team were just absolutely fantastic to work with in this process. From having been on the other side when you get 300 different comments from the editors and reviewers and you respond to them thoroughly and with grace, that's a feat in and of itself. So I want to shout out Harmony and her team for just being fantastic partners, because really we see ourselves as sort of the author's partners in kind of making the paper as good as it can be as the best it can be. Dr. Sandeep Das: So I'll admit upfront, I think it's kind of fashionable for people to say, well, I knew that this was going to show this, I knew this all from COURAGE, and this is not surprising to me. But I'll admit that I was surprised. And so this has been practice-changing for me, so this whole evolution post ischemia. And I really feel like a little bit of an existential crisis because I'm not sure I understand what ischemia means anymore. You ask me five years ago, I would've been very confident that I knew the answer to that. So you know what, really, as soon as this paper crossed our desk, I thought, wow, this is something we want to keep, this is something that's going to be really important to practice of cardiology. It's going to be really important to our readers. It's a great paper from a great group. This is something we want. So really it was never a question of, well, am I interested or am I not? I was interested from reading the abstract. Dr. Sandeep Das: So the question then became what are the real important questions that we need to sort of tease out and help elucidate for the clinician for the reader? And really for me, the question has always been, is there a subset of people where... So in my heart of hearts, I always kind of thought that burden of ischemia, if there was enough burden of ischemia, that it probably did help to revascularize that, right? I definitely practiced that way, right? There was some sort of number where I would start to say, that's a lot of ischemic myocardium and maybe we need to do something about that. Even though I know my intellectual brain says, no, there's no data that supports this, I really kind of thought it was true. And so Harmony and her team put another nail in that coffin here because it doesn't seem to be true, which to me was interesting and different and practice-changing. Dr. Sandeep Das: So the real questions here were sort of to tease out the interaction between anatomic severity, and we've all known that sort of anatomic burden of disease is proportional to adverse outcomes. That's not surprising. But the question then is, can we tease out a group where there may be benefit to revascularization? So there's a real interesting sort of interplay here between degree of ischemia and anatomic burden of disease. And is there a subset with enough of an anatomic burden of disease where you really may be interested in going after that to improve heart outcomes? So that's what I thought this was really fascinating paper. Dr. Greg Hundley: Very good. Well, David, we're going to turn to you next as the editorialist and asking you to sort of put the results of each of these two studies together. One, kind of highlighting for us how functional imaging might be useful to identify whether ischemia is present or not. And then the second study, really defining for us an association between anatomy and outcomes. So putting these all together, could you share your thoughts with us regarding these two papers? Dr. David Newby: Yes. Thank you. So I think that the CIAO-ISCHEMIA is very interesting, isn't it? And those clinicians were often challenged with symptoms versus our objective tests and trying to work out exactly what's going on, and it is. And such an important group as Harmony says, I can't agree more. We have a lot of morbidity here. As Nick said, I think the short term, a lot of the patients do seem to get better with just conservative management is good, but there's a core group that clearly are a problem. And as Harmony highlighted, you've got people with terrible regional wall-motion abnormalities on stress echo and yet no angina, others with no angina with no apparent difficulty on repeat testing. And then you've got a core group that has both, and it is fascinating to try and unpick that. And clearly, the symptoms are not correlating with our tests, and that's not the patient's fault. Dr. David Newby: And very often, no, no, you're wrong, can we say that to the patient? No, no, the patient is right and our tests are wrong, and we've got to work out how best to manage them. And I have a bit of analogy with Takotsubo cardiomyopathy as well, I think is at play here. I mean, here, you've got people with stable pain. We're not coming in as an acute emergency, but they're having regional wall motion abnormalities at times. They're getting a lot of symptoms. And we see similar things with Takotsubo, which is, I suppose, a much more flurry thing. I know that's something close to Harmony's his heart too. Excuse the pun. But this ischemia relationship, these regional wall motion abnormalities with chest pain, particularly in women, is something we really need to get our heads around and understand what's going on. It just reflects our ignorance, I think, of knowing exactly how to manage these patients. Dr. David Newby: And so for me, ischemia testing is about symptoms. It's about working out what's going on with the patient. It doesn't always give us the answer, but I certainly think that the role of ischemia testing is more about the symptoms. Dr. David Newby: And then when it comes to the second paper and outcomes with the ischemia trial, I absolutely was delighted to see those findings. I have to say place to what my prejudice is, I suppose, as someone that's been working with CT. And I suppose the slightly obvious thing is that the more disease you have, the more you will benefit from an intervention. And plaque and the burden of plaque is critical to that because how do you have a heart attack? Well, you have to have plaque, right? And it has to rupture. So the more plaque you have, the more likely you are. And I think that the analysis is again reinforcing what we've learned from some of the imaging trials with PROMIS and SCOT-HEART. Actually, the more plaque you have, the worse you are. Dr. David Newby: And yes, ischemia predicts risk, but ischemia predicts risk through its association with plaque burden, not through ischemia itself. And what I think we're seeing very nicely being played out in ischemia trial is the risk is definitely much stronger for CT than it is for imaging. And that's very clear, and that's exactly what PROMIS found exactly what SCOT-HEART found as well, and it's a rise robust finding. The interaction with the treatment effect that I find also fascinating and again plays to some of the bypass surgery trials that we've seen, bypass surgery tends to prevent spontaneous MIs and, even in some cases, mortality. And we're seeing trends in ischemia for mortality, can't over call them. I'd love to see what happens in 10 years. But I think in terms of the prevention of MIs, I'm putting all my money in one basket, which is the bypass surgery, 25% of course of patients revascularized that way. I don't believe that PCI is going to prevent the myocardial infarction. So I think all my money is in that box. Dr. David Newby: But it's absolutely fascinating data. It is all about the plaque if you're talking about prevention of clinical events downstream. And I think that's where the dichotomy is, scheme is about symptoms and understanding the patient's problems in terms of symptomatic improvement. If you want to improve their long term outcome, it's all about the plaque, understanding the burden of plaque and what you can do to hopefully prevent downstream event. Dr. Greg Hundley: Great. Thank you so much. And so listeners, we're going to ask each of our speakers today in really 20 or 30 seconds to go through and identify what do they think is the next study really to be performed in this space? So Harmony, we're going to start with you and then Nick, Sandeep and then finish up with David. Harmony? Dr. Harmony Reynolds: Thanks. Well, when it comes to INOCA, I would like to see more studies in the vein of CorMicA. So I'd like to see routine invasive testing to define the underlying pathophysiology problem and then targeted medical therapy interventions, and I'd like to see outcome trials. There's one outcome trial going on. It's a challenge because the event rate, though very important and higher than in the general population for sure, is low enough that these trials have to be quite large, and we look at ischemia with a relatively high event rate. And even so it's a stable population and that had to be large, this would have to be even larger. So we're going to need more mechanistic studies in order to lead to the treatment trials that will really influence practice. Dr. Harmony Reynolds: And in terms of the severity of coronary disease, this is a tough one. We felt like ischemia was a lift, and I'm not sure that there will be another huge stable ischemic heart disease trial. But sure, I'd love to see in people selected by CT for their advanced severity of coronary disease, whether an invasive management strategy makes a difference compared to medical therapy. I don't know that we'll see that one come to pass, but you never know. Dr. Greg Hundley: Nick? Dr. Nicholas Mills: Yeah. I agree. We need more mechanistic research, but I'd like to see more non-invasive methods to understand the mechanistic basis of this condition because CorMicA has caught an invasive protocol for a condition, which we know is benign and who most patients get better without any treatment. I would also like to see randomized blinded studies of treatment effects and because there are too many observational on blinded studies here. And I think the outcome has to be patient-focused and symptoms. Dr. Greg Hundley: Sandeep? Dr. Sandeep Das: Yeah. So everything that's been raised so far are fantastic comments and really on point. For me, I think if we can tease out the population that may benefit to get back to Dave's earlier comment that there's possibly not going to be a little humble here, there's possibly a population that has extensive, extensive CVD that could benefit from bypass surgery. And I think that that hasn't really been firmly demonstrated yet, although it's been suggested strongly. So that I think is an interesting study, and I hope that that gets done as a trial, but I can understand that it'd be a giant undertaking. And then the other thing I think is just algorithmic approaches that are driven by anatomical studies like SCOT-HEART and things like that, where we really try to make decisions based on the anatomical approach and pretend like the last 15 years never happened and that we kind are starting fresh with our best approach to how to treat these patients. Dr. Greg Hundley: And finally, David. Dr. David Newby: Yeah. I'm actually going to agree with everybody there, and I'm rooting for this trial actually because that's the one I want to do is look at advanced coronary disease on noninvasive imaging, irrespective of symptoms. And that's the big call actually if you've got no symptoms to put yourself through a bypass, because it's bypass, it's not standing. Bypass, we need. I'd also love to see some substudy coming out of ischemia. I think you're doing them. I hope you are looking at plaque burden and plaque characteristics because I think that's another level of complexity. We're so obsessed with stenosis, actually. And again, even anatomical and ischemia testing plays to that, it's not just about stenosis, stenotic arteries have big plaque burdens, et cetera. And it's not bypassing them, it's bypassing all the nonobstructive plaque and the obstructive plaque that has given you the benefit of revascularization with surgery. So I think you need to think about a really nice cool trial where we can do that trial even in the presence of nonobstructive disease, but big plaque burden, adverse plaque characteristics, and think about bypass. Dr. Greg Hundley: Very nice. Well, listeners, we want to thank Dr. Harmony Reynolds for bringing us these two really informative studies from the ischemia trial, and also our associate editors, Dr. Nick Mills and Dr. Sandeep Das for providing their perspective and our editorialist, Dr. David Newby, who really helped us organize our thoughts and put both of these two studies into great perspective highlighting in the first that functional testing can really help us identify the presence or absence of ischemia. And then our second study highlighting the association between CT coronary angiography and the identification of the anatomic severity of disease with cardiac outcomes. Dr. Greg Hundley: Well, on behalf of Carolyn and myself, we want to wish you a great week and we will catch you next week on the run. This program is copyright of the American Heart Association 2021. The opinions expressed by speaker in this podcast are their own and not necessarily those of the editors or of the American Heart Association. For more, visit ahajournals.org.

#146 - QDM de Poche - Le livre "Réinventer l'amour" de Mona Chollet

Nerds, Geeks, and the Kitchen Sink

Play Episode Listen Later Sep 26, 2021 20:33

Être féministe et hétérosexuelle, toujours compatible en 2021 ? L'autrice et journaliste Mona Chollet marque le début de cette rentrée littéraire avec un nouveau best-seller : “Réinventer l'amour. Comment le patriarcat sabote les relations hétérosexuelles". Après "Chez soi" et "Sorcières", l'autrice propose une réflexion sur l'impact du patriarcat au sein des relations hétérosexuelles. Entre charge mentale et violences conjugales, Mona Chollet nous appelle à revendiquer notre place dans la définition de ce que nous appelons l'Amour. Clémentine Gallot et Emeline Amétis se sont penchées sur cette œuvre et nous en parlent dans ce nouvel épisode court de Quoi de Meuf. Les références entendues dans cet épisode : Mona Chollet, “Réinventer l'amour. Comment le patriarcat sabote les relations hétérosexuelles”, La Découverte (2021)Mona Chollet, “Sorcières. La puissance invaincue des femmes”, La Découverte (2018)Mona Chollet, “Chez soi. Une odyssée de l'espace domestique”, La Découverte (2015)Mona Chollet, “Beauté fatale. Les nouveaux visages d'une aliénation féminine “, La Découverte (2015)Elizabeth Jane Ward, “The tragedy of heterosexuality”, New York University Press (2020)Colette Dowling, Cendrillon et l'argent. Le nouveau combat des femmes”, Édition Grasset (1999)Monique Wittig est une romancière, philosophe, théoricienne et militante féministe lesbienne française. Elle a considérablement marqué la théorie féministe grâce au concept de “contrat hétérosexuel”. Adrienne Rich est une poétesse, essayiste, professeure d'université et théoricienne féministe américaine.Carol Gilligan et Naomi Snider, “Pourquoi le patriarcat ?”, Flammarion (2021)Annik Houel est une psychologue et féministe française, professeure émérite en psychologie sociale à l'université Lumière Lyon 2. Elle est membre de l'Association nationale des études féministes, qu'elle présida pendant plusieurs années, et co-fondatrice du Centre Louise Labé. Houel Annik, Patricia Mercader, et Helga Sobota, “Crime passionnel, crime ordinaire”, Presses Universitaires de France (2003)Marie-Carmen Garcia, “Amours clandestines : nouvelle enquête - L'extraconjugalité durable à l'épreuve du genre”, PUL (2021)Liv Stromquist, “Les sentiments du Prince Charles”, Rackham (2010)Quoi de Meuf est une émission de Nouvelles Écoutes. Rédaction en chef : Clémentine Gallot. Journalistes chroniqueuses : Emeline Amétis, Kaoutar Harchi, Anne-Laure Pineau, Pauline Verduzier. Mixage et montage par Laurie Galligani. Prise de son par Adrien Beccaria à l'Arrière Boutique. Générique réalisé par Aurore Meyer Mahieu. Réalisation et coordination par Cassandra de Carvalho et Mathilde Jonin. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 - The Hailon System

Intergalactic Radio

Play Episode Listen Later Sep 25, 2021 21:56

In this episode Tyko and Lad interview a weird stranger. Also, Guy is missing... Today's show is sponsored by Infinite Hard, other brands may say they're hard, but... we're... harder.

system lad tyko

Playstation Showcase + Deathloop + Malignant

Play Episode Listen Later Sep 19, 2021 86:18

The Playstation Showcase blew our minds! In this episode we break down all the games that were announced, as well as going deep on the first few hours of Deathloop! We also give a sneak peak of Umar Ditta's fantastic Lad #3, which will soon be available at : https://umarditta.gumroad.com/ Please, SUPPORT THIS COMIC! We finish our conversation by discussing the new James Wan film "Malignant" Join our Discord and chat with us and other listeners!: discord.gg/mHQZd47xvy Get us on Twitter @geekssinks @dkrefft and @cdstein69 Like us on Facebook and get into the conversation! Email us at nerdsgeekssinks@gmail.com Check out our online store for MERCH! www.redbubble.com/people/nerdsgeekssinks

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#145 - La rentrée littéraire 2021

Play Episode Listen Later Sep 19, 2021 41:01

Les chroniqueuses de Quoi de Meuf reviennent en force pour cette 5ème saison qui s'annonce pleine de rebondissements. 521 romans ont été publiés en 2021 : on retrouve entre autres ceux de Christine Angot, de Natasha Trethewey ou encore de Salomé Kiner. Clémentine, Pauline, Anne-Laure, Kaoutar et Émeline nous débriefent cette rentrée littéraire. Les références entendues dans cet épisode : Camille Kouchner, “La familia grande”, Éditions du Seuil (2021)Christine Angot, “Le Voyage dans l'Est”, Flammarion (2021)Salomé Kiner, “Grande couronne”, Bourgois (2021)La série The White Lotus de Mike White (2021)Natasha Trethewey, “Memorial Drive”, Éditions de l'Olivier (2020)Amandine Gay, “Une poupée en chocolat”, La Découverte (2021)Une histoire à soi d'Amandine Gay (2021)Ouvrir la voix d'Amandine Gay (2017)Laura Nsafou, “Nos Jours Brûlés”, Albin Michel (2021)Maryse Condé, “L'Evangile du nouveau monde”, Buchet Chastel (2021)Maryse Condé, “La vie sans fards”, JC Lattès (2012)Maryse Condé, “Moi Tituba sorcière noire de Salem”, Gallimard (1988)Jean Hegland, “Dans la forêt”, Gallmeister (2018)Corinne Royer, “Pleine Terre”, Actes Sud (2021)Jean Hegland, “Apaiser nos tempêtes”, Éditions Phébus (2021)Ananda Devi, “Le rire des déesses”, Éditions Grasset (2021)Agnès Desarthe, “L'éternel fiancé”, Éditions l'Olivier (2021)Roukiata Ouedraogo, “Ouagadougou pressé”, Sarbacane (2021)Quoi de Meuf est une émission de Nouvelles Écoutes.Rédaction en chef : Clémentine Gallot. Journalistes chroniqueuses : Emeline Amétis, Kaoutar Harchi, Anne-Laure Pineau, Pauline Verduzier. Mixage et montage par Laurie Galligani. Prise de son par Adrien Beccaria à l'Arrière Boutique. Générique réalisé par Aurore Meyer Mahieu. Réalisation et coordination par Cassandra de Carvalho et Mathilde Jonin. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ressusciter des mammouths, élections historiques, le pass sanitaire... Actus du jour

Radio foot internationale

Play Episode Listen Later Sep 17, 2021 9:17

Chaque jour, en moins de 10 minutes, un résumé de l'actualité du jour. Rapide, simple, efficace. SOURCES ÉLECTIONS ALLEMAGNE : Le Monde, France 24, BoursoramaMAMMOUTHS : Sciences et Avenir, France 24, National Geographic HARCELEMENT 2010 : Libération, BFM TVVIRUS DE MARBURG : Le Monde, OMS COVID-19 : Le Huffington Post, La Dépêche ROBERT BADINTER : BFM TV, Libération, INAÉcriture : Blanche Vathonne - Paul Bonnaud - Manon Tallien de Cabarrus - Hugo Travers Montage : Camille Paulet Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out.

france pass jour lad actus avenir rapide sanitaire historiques

Radio Foot Internationale - L'OM monte sur le podium !

Play Episode Listen Later Sep 13, 2021 48:30

Au sommaire de Radio Foot ce lundi, Ligue 1, l'OM monte sur le podium ! Victorieux 2-0 à Monaco, les Olympiens ont réalisé un joli coup grâce notamment à Bamba Dieng auteur d'un doublé ! Le jeune attaquant sénégalais formé à Diambars a impressionné, peut-il être l'un des hommes forts de l'attaque marseillaise cette saison ? Monaco nouvelle chute ! Pourquoi les hommes du Rocher ont-ils pris la fâcheuse habitude de patiner en début de saison ? Nice, défense de fer ! Troisième victoire de rang à Nantes (0-2) et toujours pas le moindre but encaissé depuis le début de la saison ! « La meilleure attaque, c'est La Défense » bonne recette pour s'immiscer dans la bataille au titre ? Premier League : CR7 fait chavirer Old Trafford ! Un doublé pour son retour, le Portugais va-t-il réussir son pari et redonner du lustre au Red Devils? Et de pour Mo Salah ! 100 buts en 162e apparition dans l'élite avec le maillot de Liverpool. Cinquième joueur le plus rapide atteindre ce seuil en Angleterre. Tottenham chute devant Crystal Palace, première victoire de Patrick Vieira à la tête du club de la banlieue sud de Londres. Le Français a-t-il enfin pris ses marques ? Liga: Benzegol pour fêter le retour à Barnabeu ! De nouveau magistral face au Celta Vigo en signant un triplé et une passe décisive, l'attaquant Merengue est-il dorénavant la grande Star de cette Liga ? Camavinga, une première madrilène et un but ! Entrée réussie pour le jeune milieu bleu ? Pour en débattre autour d'Olivier Pron, nos consultants du jour Nabil Djellit, Carine Galli et Salim Baungally — David Fintzel — TCR : Laurent Salerno

Épisode 60 : Le témoin protégé qui a évité un nouvel attentat

Expliquez-nous le monde

Play Episode Listen Later Sep 10, 2021 10:02

Le procès des attentats du 13 novembre a de quoi donner le tournis : 9 mois d'audiences, pour entendre des témoignages qui resteront dans l'Histoire. Parmi eux celui de Sonia qui a empêché Abdelhamid Abaaoud de commettre un nouvel attentat à La Défense, on vous explique !

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Un suppositoire pour soigner le Covid-19, procès historique, Bitcoin légalisé... Actus du jour

jesus christ quatre lad chemins avec m haack picardie jules verne viiie

Play Episode Listen Later Sep 7, 2021 9:39

Chaque jour, en moins de 10 minutes, un résumé de l'actualité du jour. Rapide, facile, accessible. SOURCES :PROCÈS ATTENTATS : France Info, BFM TV, Le Point TRAITEMENTS COVID : La Dépêche, La Dépêche, Le JDD, France Info, France 3BELMONDO : France Info, Le MondePRÉOCCUPATIONS FRANÇAIS : Le MondeSTATUE CHRISTOPHE COLOMB : Ouest France, France 24BITCOIN SALVADOR : France 24, Les Echos PRISON VIETNAM : L'Est républicain, Reuters Écriture : Blanche Vathonne - Paul Bonnaud - Manon de Cabarrus - Hugo Travers Montage : Stanley Duplan Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out.

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Chemins d'histoire-Etrusques et étruscologie, avec M.-L. Haack, 05.09.21

Chemins d’histoire

Play Episode Listen Later Sep 5, 2021 56:37

Quatre-vingt-troisième numéro de Chemins d'histoire, deuxième numéro de la troisième saison, émission animée par Luc Daireaux Émission diffusée le dimanche 5 septembre 2021 Thème : Etrusques, étruscologie, étruscomanie, du VIIIe siècle avant Jésus-Christ à nos jours Invitée : Marie-Laurence Haack, professeure d'histoire ancienne à l'université de Picardie-Jules Verne, autrice d'A la découverte des Etrusques, La Découverte, 2021.

La Chine force les jeunes à travailler, Kim Jong Un convoqué, polémique à Marseille... Actus du jour

Play Episode Listen Later Sep 3, 2021 9:50

Chaque jour, en moins de 10 minutes, un résumé de l'actualité du jour. Rapide, facile, accessible. SOURCES : SYRIE ESPIONNAGE VACCINS : Mediapart, L'Express, France 24 INTERNET CONTRÔLÉ EN CHINE : Le Monde, 20 Minutes, Le Point, Le Point OURAGAN IDA : New York Times, LCI MARSEILLE ENSEIGNANTS : Le Monde, LCI, Le ParisienCORÉE DU NORD : Le Monde, La Dépêche Écriture : Anais Lochon - Paul Bonnaud - Manon de Cabarrus - Hugo Travers Montage : Stanley Duplan See acast.com/privacy for privacy and opt-out information.

france force kim jong un travailler jour marseille lad la chine actus lci les jeunes rapide jong-un le point mique

Un cube nazi recherché, Macron à Marseille, New York inondé... Actus du jour

Play Episode Listen Later Sep 2, 2021 10:13

Chaque jour, en moins de 10 minutes, un résumé de l'actualité du jour. Rapide, facile, accessible. MACRON À MARSEILLE : Le Monde, Le Point, Ouest France, France Inter, La Dépêche CUBE D'URANIUM NAZI : Washington Post, Business AM, L'ObsNEW YORK INONDÉ : France Info, BFM TV, NY TimesAVORTEMENT AU TEXAS : Le Monde, NY Times, LibérationMACRON ET MCFLY & CARLITO : BFM TVÉcriture : Anais Lochon - Paul Bonnaud - Manon de Cabarrus - Hugo Travers Montage : Stanley Duplan See acast.com/privacy for privacy and opt-out information.

new york new york times nazis cube macron jour marseille france inter lad actus rapide recherch le point bfmtv ouest france

MLB DFS Strategy 9/1/2021

Play Episode Listen Later Sep 1, 2021 51:56

We get another action-packed slate today for DraftKings and FanDuel. You'll want to be locked into the Awesemo MLB DFS Strategy Show. Join Josh Engleman and Adam Scherer as they navigate the MLB daily fantasy options on 9/1/21 for The MLB DFS Strategy Show. The guys will go game-by-game identifying the top plays of the day. Don't miss all of their top picks. Subscribe to our Fantasy Football channel http://awese.moe/FFSub Subscribe to our Sports Betting channel http://awese.moe/OddsSub Get access to exclusive Awesemo promos, giveaways, and featured content for FREE by joining our daily newsletter: https://www.awesemo.com/email/NEW USERS! Click the link here to get 25% OFF your first week of Awesemo+ Platinum! http://awese.moe/MLBSTRATEGYSHOWMLB STRATEGY SHOW - 0:00BAL (+213) @ TOR (10.0) - 5:21NYY (-270) @ LAA (8.5) - 12:09BOS (-100) @ TB (7.5) - 19:28OAK (-165) @ DET (9.5) - 23:16CLE (+112) @ KC (9.0) - 30:00CHC (+148) @ MIN (9.0) - 34:50PIT (+287) @ CWS (8.5) - 41:00MIL (+152) @ SF (7.5) - 45:47ATL (+190) @ LAD (7.5) - 49:06Awesemo's MLB DFS & Betting Strategy + ToolsMLB Props Tool: https://www.awesemo.com/mlb/mlb-player-props/MLB Betting Model: https://www.awesemo.com/mlb/mlb-power-rankings/MLB DFS Primer: https://www.awesemo.com/mlb/mlb-dfs/How To Win DFS Tournaments: https://www.awesemo.com/gameplan/how-to-win-at-dfs-tournaments/How To Use MLB Fantasy Cruncher https://www.awesemo.com/mlb/optimizing-your-mlb-dfs-process-with-fantasy-cruncher-the-fantasy-crunch/MLB DFS Projections: https://www.awesemo.com/mlb/mlb-dfs-projections-for-draftkings-and-fanduel/MLB DFS Rankings: https://www.awesemo.com/mlb/awesemos-mlb-rankings/MLB Ownership Projections: https://www.awesemo.com/mlb/mlb-draftkings-ownership-projections/MLB DFS Top Stacks: https://www.awesemo.com/mlb/mlb-dfs-top-stack-for-draftkings/MLB DFS Top Pitchers: https://www.awesemo.com/mlb/mlb-dfs-top-pitcher-for-draftkings/#Baseball #DailyFantasy #Picks #MLBDFS #MLBNews #MLBLineups #MLBWeather #MLBDFSPicks #DraftKings #FanDuel More Awesemo PlatformsYouTube | http://awese.moe/youtubeTwitter | @Awesemo_Com | http://awese.moe/TwitterInstagram | @Awesemo_Com | http://awese.moe/IGFacebook | @AwesemoCom | awese.moe/FBFacebook Group | http://awese.moe/FBgroupApple Podcasts | http://awese.moe/podSpotify | http://awese.moe/SpotifyTwitch | http://awese.moe/Twitch

MLB DFS Strategy 8/30/21

One Thing In A French Day

Play Episode Listen Later Aug 30, 2021 58:21

We get another action-packed slate today for DraftKings and FanDuel, you'll want to be locked into the Awesemo MLB DFS Strategy Show. Join Greg Ehrenberg and Adam Scherer as they navigate the MLB daily fantasy options on 8/30/21 for The MLB DFS Strategy Show. The guys will go game-by-game identifying the top plays of the day. Don't miss all of their top picks for every matchup on the main slate. 15% off Awesemo+ NFL Annual http://awese.moe/BLITZ Subscribe to our Fantasy Football channel http://awese.moe/FFSub Subscribe to our Sports Betting channel http://awese.moe/OddsSub Get access to exclusive Awesemo promos, giveaways, and featured content for FREE by joining our daily newsletter: https://www.awesemo.com/email/NEW USERS! Click the link here to get 25% OFF your first week of Awesemo+ Platinum! http://awese.moe/MLBSTRATEGYSHOWMLB STRATEGY SHOW - 0:00PHI (8.5) @ WAS (+130) - 4:00BAL (9.5) @ TOR (-335) - 10:09BOS (8.5) @ TB (-135) - 17:11COL (8.5) @ TEX (+120) - 22:00NYY (8.5) @ LAA (+125) - 29:40SDP (9.5) @ ARI (+160) - 34:00MIL (7.5) @ SFG (+115) - 42:00ATL (8.5) @ LAD (-220) - 48:06HOU (8.5) @ SEA (+135) - 54:00Awesemo's MLB DFS & Betting Strategy + ToolsMLB Props Tool: https://www.awesemo.com/mlb/mlb-player-props/MLB Betting Model: https://www.awesemo.com/mlb/mlb-power-rankings/MLB DFS Primer: https://www.awesemo.com/mlb/mlb-dfs/How To Win DFS Tournaments: https://www.awesemo.com/gameplan/how-to-win-at-dfs-tournaments/How To Use MLB Fantasy Cruncher https://www.awesemo.com/mlb/optimizing-your-mlb-dfs-process-with-fantasy-cruncher-the-fantasy-crunch/MLB DFS Projections: https://www.awesemo.com/mlb/mlb-dfs-projections-for-draftkings-and-fanduel/MLB DFS Rankings: https://www.awesemo.com/mlb/awesemos-mlb-rankings/MLB Ownership Projections: https://www.awesemo.com/mlb/mlb-draftkings-ownership-projections/MLB DFS Top Stacks: https://www.awesemo.com/mlb/mlb-dfs-top-stack-for-draftkings/MLB DFS Top Pitchers: https://www.awesemo.com/mlb/mlb-dfs-top-pitcher-for-draftkings/#Baseball #DailyFantasy #Picks #MLBDFS #MLBNews #MLBLineups #MLBWeather #MLBDFSPicks #DraftKings #FanDuel More Awesemo PlatformsYouTube | http://awese.moe/youtubeTwitter | @Awesemo_Com | http://awese.moe/TwitterInstagram | @Awesemo_Com | http://awese.moe/IGFacebook | @AwesemoCom | awese.moe/FBFacebook Group | http://awese.moe/FBgroupApple Podcasts | http://awese.moe/podSpotify | http://awese.moe/SpotifyTwitch | http://awese.moe/Twitch

CYF 088 — Podcast enregistré à La Défense, quartier d'affaires

Cultivate your French

Play Episode Listen Later Aug 25, 2021 6:50

La Défense is a big business district located west of Paris. It's not far from where I live. It's only 4 minutes by train. And this is where I was on Monday afternoon. I had taken the girls to the cinema inside the enormous shopping centre. I had two hours to spare so I decided to record this episode right at the foot of the Grande Arche, the building that ends the « axe historique » of Paris. Then I walked and took photos of the different works of art that I had just mentioned in the episode. Including the statue of La Défense by Barrias which gave its name to the district. It was erected in 1883 to the glory of the French soldiers of the 1870 war with Prussia. You are listening to Cultivate Your French podcast One Slow French episode every week. My name is Laetitia, I'm French, I live just outside Paris and I share with you a small slice of my daily life here in France. All the information about the transcript,notes and photos is available at www.cultivateyourfrench.com

french france enregistr quartier lad prussia

Chemins d'histoire-Nouveaux regards sur la Saint-Barthélemy, avec J. Foa, 24.08.21

Chemins d’histoire

Play Episode Listen Later Aug 23, 2021 62:18

Quatre-vingt-deuxième numéro de Chemins d'histoire, premier numéro de la troisième saison, émission animée par Luc Daireaux Émission diffusée le mardi 24 août 2021 Thème : Nouveaux regards sur la Saint-Barthélemy (1572) Invité : Jérémie Foa, maître de conférences HDR à Aix-Marseille Université, chercheur auprès de l'Institute for Advanced Study de Princeton, auteur de Tous ceux qui tombent. Visages du massacre de la Saint-Barthélemy, La Découverte, septembre 2021.

advanced study institute hdr lemy nouveaux quatre lad visages chemins foa avec j saint barth

2023 — lundi 23 août 2021 — Podcast enregistré à La Défense

Play Episode Listen Later Aug 23, 2021 6:02

Aujourd'hui, un nouveau podcast enregistré en extérieur. Je suis, cet après-midi, lundi 23 août, à La Défense, au pied de la Grande Arche. La Défense, vous en avez peut-être déjà entendu parler. Peut-être sur ce podcast ou peut-être que vous êtes déjà venu. C'est le quartier d'affaires à l'ouest de Paris. C'est le premier quartier d'affaires d'Europe. C'est un drôle de nom vous ne trouvez pas, La Défense ? La suite du texte est dans le TRANSCRIPT, abonnez-vous! http://bit.ly/OneThingTranscripts

aujourd enregistr peut transcript lundi lad

MLB DFS Strategy 8/18/21

Play Episode Listen Later Aug 18, 2021 49:03

Wednesday brings 15 games to build daily fantasy baseball lineups on DraftKings and FanDuel. Join Josh Engleman and Adam Scherer as they navigate the MLB DFS options on 8/18/21 for The MLB DFS Strategy Show. The guys will go game-by-game identifying the top plays of the day, including Rafael Devers. Don't miss all of their top MLB DFS picks and FREE expert picks for every matchup on the main slate. Presented by OddsShopper.25% off Awesemo+ NFL Annual http://awese.moe/BLITZSubscribe to our Fantasy Football channel http://awese.moe/FFSubSubscribe to our Odds channel http://awese.moe/OddsSubNEW USERS! Click the link here to get 25% OFF your first week of Awesemo+ Platinum! http://awese.moe/MLBSTRATEGYSHOWEarly Slate - 0:00BOS (-101) @ NYY (10.0) - 11:37LAA (-136) @ DET (8.5) - 16:39BAL (+190) @ TB (9.0) - 21:10ATL (-198) @ MIA (7.5) - 26:13MIL (-112) @ STL (7.0) - 31:10SEA (-163) @ TEX (9.0) - 34:40OAK (+170) @ CWS (8.5) - 40:18HOU (-163) @ KC (9.5) - 45:15PHI (-135) @ ARI (8.5) - 50:20PIT (+235) @ LAD (9.0) - 35:50Awesemo's MLB DFS & Betting Strategy + ToolsMLB Props Tool: https://www.awesemo.com/mlb/mlb-player-props/MLB Betting Model: https://www.awesemo.com/mlb/mlb-power-rankings/MLB DFS Primer: https://www.awesemo.com/mlb/mlb-dfs/How To Win DFS Tournaments: https://www.awesemo.com/gameplan/how-to-win-at-dfs-tournaments/How To Use MLB Fantasy Cruncher https://www.awesemo.com/mlb/optimizing-your-mlb-dfs-process-with-fantasy-cruncher-the-fantasy-crunch/MLB DFS Projections: https://www.awesemo.com/mlb/mlb-dfs-projections-for-draftkings-and-fanduel/MLB DFS Rankings: https://www.awesemo.com/mlb/awesemos-mlb-rankings/MLB Ownership Projections: https://www.awesemo.com/mlb/mlb-draftkings-ownership-projections/MLB DFS Top Stacks: https://www.awesemo.com/mlb/mlb-dfs-top-stack-for-draftkings/MLB DFS Top Pitchers: https://www.awesemo.com/mlb/mlb-dfs-top-pitcher-for-draftkings/#MLBDFS #MLBNews #MLBLineups #MLBWeather #MLBDFSPicks #DraftKings #FanDuel #Picks #Awesemo #DailyFantasyBaseballFollow us onYouTube | http://awese.moe/youtubeTwitter | @Awesemo_Com | http://awese.moe/TwitterInstagram | @Awesemo_Com | http://awese.moe/TwitterFacebook | @AwesemoCom | http://awese.moe/IGFacebook Group | http://awese.moe/FBgroupApple Podcasts | http://awese.moe/podSpotify | http://awese.moe/SpotifyTwitch | http://awese.moe/Twitch

MLB DFS Strategy 8/16/21

Mile High Endurance Podcast

Play Episode Listen Later Aug 16, 2021 60:14

Monday delivers 10 games of night baseball to build daily fantasy baseball lineups on DraftKings and FanDuel. Join Greg Kaufman and Adam Scherer as they navigate the MLB DFS options on 8/16/21 for The MLB DFS Strategy Show. The guys will go game-by-game identifying the top plays of the day including Zack Wheeler. Don't miss all of their top MLB DFS picks and FREE expert picks for every matchup on the main slate.Stream begins at 11:00 a.m. ET sponsored by OddsShopper.25% off Awesemo+ NFL Annual http://awese.moe/BLITZSubscribe to our Fantasy Football channel http://awese.moe/FFSubSubscribe to our Odds channel http://awese.moe/OddsSubMLB Strategy Show - 0:00LAA (8.5) @ NYY (-280) - 3:50CHC (9.5) @ CIN (-220) - 8:09ATL (8.5) @ MIA (+140) - 15:45BAL (8.5) @ TB (-280) - 23:01OAK (9) @ CWS (-105) - 27:00HOU (10) @ KC (+135) - 33:43CLE (9.5) @ MIN (-130) - 40:00SD (12.5) @ COL (+115) - 46:49NYM (8.5) @ SF (-210) - 53:20PIT (9) @ LAD (-320) - 59:00NEW USERS! Click the link here to get 25% OFF your first week of Awesemo+ Platinum! http://awese.moe/MLBSTRATEGYSHOWAwesemo's MLB DFS & Betting Strategy + ToolsMLB Props Tool: https://www.awesemo.com/mlb/mlb-player-props/MLB Betting Model: https://www.awesemo.com/mlb/mlb-power-rankings/MLB DFS Primer: https://www.awesemo.com/mlb/mlb-dfs/How To Win DFS Tournaments: https://www.awesemo.com/gameplan/how-to-win-at-dfs-tournaments/How To Use MLB Fantasy Cruncher https://www.awesemo.com/mlb/optimizing-your-mlb-dfs-process-with-fantasy-cruncher-the-fantasy-crunch/MLB DFS Projections: https://www.awesemo.com/mlb/mlb-dfs-projections-for-draftkings-and-fanduel/MLB DFS Rankings: https://www.awesemo.com/mlb/awesemos-mlb-rankings/MLB Ownership Projections: https://www.awesemo.com/mlb/mlb-draftkings-ownership-projections/MLB DFS Top Stacks: https://www.awesemo.com/mlb/mlb-dfs-top-stack-for-draftkings/MLB DFS Top Pitchers: https://www.awesemo.com/mlb/mlb-dfs-top-pitcher-for-draftkings/#MLBDFS #MLBNews #MLBLineups #MLBWeather #MLBDFSPicks #DraftKings #FanDuel #Picks #Awesemo #DailyFantasyBaseballFollow us onYouTube | http://awese.moe/youtubeTwitter | @Awesemo_Com | http://awese.moe/TwitterInstagram | @Awesemo_Com | http://awese.moe/TwitterFacebook | @AwesemoCom | http://awese.moe/IGFacebook Group | http://awese.moe/FBgroupApple Podcasts | http://awese.moe/podSpotify | http://awese.moe/SpotifyTwitch | http://awese.moe/Twitch

Taylor Knibb Boulder 70.3

Play Episode Listen Later Aug 14, 2021 76:30

This week we have one of the silver medalists from that very Olympic Mixed Relay, that's right pro triathlete, Olympian and Silver Medalist, not to mention 2nd place at her first IRONMAN 70.3 in Boulder this past weekend…Taylor Knibb. Show Sponsor: VENGA CBD Still loving the Venga CBD Super Sleep. It has Melatonin, CBD AND an all-new cannabinoid CBN that's been shown to promote sleep. You'll wake up well-rested and refreshed because Venga Super Sleep is all-natural and works with your body's systems to promote a great night's sleep. As with all of Venga CBD's products, Super Sleep is 100% THC-free and non-habit forming. Just go to https://vengaendurance.com/303podcast to order yours today. First-time order is 30% off with code (303PODCAST). We've also added 50% off your first month's subscription with code (303SUBSCRIPTION). In Today's Show Feature interview - Taylor Knibb Endurance News - Tim O'Donnell, Katie Compton What New in the 303 - Boulder 70.3; Triple Bypass next weekend Video of the Week - TO About His Heart Attack Interview Sponsor: UCAN Take your performance to the next level with UCAN Energy and Bars made with SuperStarch® UCAN uses SuperStarch instead of simple sugars to fuel serious athletes. UCAN keeps blood sugar steady compared to the energy spikes and crashes of sugar-based products. Steady energy equals sustained performance! You put in the training, so don't let nutrition limit your performance. Use UCAN in your training and racing to fuel the healthy way, finish stronger and recover more quickly! Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co, Interview with Taylor Knibb Taylor Knibb at 23, is the youngest woman ever to qualify for the U.S. Olympic Triathlon Team. She has been the USA Triathlon National Team's youngest member since she first made the team in 2017. Knibb was inspired to become a triathlete as a child after she watched her mom, Leslie Knibb, compete in an IRONMAN race and noticed the positive atmosphere. She tried a kids' race and was hooked on the sport from there, working her way through USA Triathlon's youth elite and junior elite pipelines. Up to this day, her favorite part of competing in triathlons is the camaraderie within the triathlon community, as well as the challenge of always growing and improving within the sport. In high school, she joined her school's cross-country team and swam for Nation's Capital Swim Club while continuing to compete in triathlons. She was named the Washington D.C. Gatorade Cross Country Runner of the Year and the D.C. State Athletic Association Runner of the Year in both 2014 and 2015. She was the 2015 and 2016 USA Triathlon Junior Elite national champion, the 2015 ITU Junior World Championships silver medalist, the 2016 and 2017 ITU Junior World Champion and the 2018 Under-23 World Champion— one of just three women ever to capture world titles at both the Junior and U23 levels. She also became the youngest woman to earn a spot on the podium at an ITU World Triathlon Series race in 2017, earning silver in Edmonton, Alberta, Canada. Knibb is a 2020 graduate of Cornell, where she ran NCAA track and cross-country for four years while balancing her elite triathlon career. She also joined the Cornell swim team her senior year. Today, Knibb trains in Boulder, Colorado, with Origin Performance Squad, an elite international training group coached by Ian O'Brien. Knibb considers the ITU Under-23 World Championships to be one of her favorite moments of her career because she accomplished a solid performance across all three disciplines. Elite Triathlon Career 2021: Won gold at the 2021 World Triathlon Championship Series Yokohama on May 15, qualifying for the 2020 U.S. Olympic Triathlon Team • Made her Olympic debut on July 27 in Tokyo, placing 16th in the women's individual event • Won a silver medal in the debut of Triathlon Mixed Relay at the Olympic Games, alongside U.S. teammates Katie Zaferes, Kevin McDowell and Morgan Pearson. Knibb is the youngest U.S. triathlete ever to win an Olympic medal. Our News is sponsored by Buddy Insurance. It's big time training and racing season. Buddy Insurance is the kind of peace of mind so you can enjoy your training and racing to their fullest. Buddy's mission is simple, to help people fearlessly enjoy an active and outdoor lifestyle. You can now get on-demand accident insurance to make sure you get cash for bills fast and fill any gaps between your current coverage. Go to buddyinsurance.com and create an account. There's no commitment or charge to create one. Once you have an account created, it's a snap to open your phone and in a couple clicks have coverage for the day. Check it out! Endurance News: Tim O'Donnell Heart Attack On March 12th, 2021 Tim suffered a heart attack during Challenge Miami. 80% of the main artery in his heart was blocked. Meaning he was only getting 20% of the blood he should have been to his heart. Called the Widow Maker as its the most lethal blockage. Its blockage of the LAD (left anterior descending artery) which is the main artery supplying the heart with blood. Katie Compton Receives a 4-Year Ban From Cycling for a Positive Doping Test Katie Compton has been banned from cycling for four years, retroactive to September 16, 2020, because of a positive doping test. In a statement, the cyclocross champion announced that she never knowingly took a banned substance, and she made the decision to retire back in March. Fifteen-time U.S. national cyclocross champion Katie Compton, 42, has received a four-year suspension on competition from the U.S. Anti-Doping Agency (USADA) after testing positive for a banned substance, the agency announced on August 11. Compton tested positive for an anabolic agent on an out-of-competition test taken on September 16, 2020. “Her urine sample was analyzed using a specialized test, known as Carbon Isotope Ratio testing, that differentiates between anabolic androgenic steroids (AAS) naturally produced by the body and prohibited anabolic agents of external origin. Anabolic agents have powerful performance-enhancing capabilities and can give an athlete an unfair advantage over fellow competitors,” the USADA statement explained. Compton's ban begins retroactively, from the day her positive sample was taken. That means all of her results, race points, and prizes received since September 16, 2020, are forfeit. Compton released a statement addressing the USADA's announcement. She said her results for that sample originally came back negative for any banned substances. USADA decided to re-test it after her Athlete Biological Passport (bio-passport) was flagged for an “irregularity.” The second test of the sample came back positive for an anabolic androgenic steroid, Compton said. “This news comes with great heartache and sadness, and it is the worst possible way to end my cycling career. I need to preface this news with the fact that I have always been a clean athlete, and I am proud of how much I have accomplished racing clean and being very careful with whatever I put into my body, especially after dealing with so many health issues throughout my life. I provided a sample for USADA in September 2020 that came back negative for any banned substances, it was not even atypical. That news was communicated to me in the same way it has always been via a letter from USADA. I've received that same letter after every test I've submitted for the last 19 years. In early February of 2021, after returning from a difficult race season, I learned that the same sample from September was re-analyzed due to a bio-passport irregularity and found to be positive for an exogenous anabolic steroid. This was devastating news to me as I have never intentionally or knowingly put anything like that into my body. I know how delicate women's hormones are, and I would never choose to take anything to jeopardize my health and, as a result, suffer irreparable damage to my endocrine system. And not only that, I never took anything for ethical and moral reasons; I've been a strong proponent of clean sport my entire career and feel doing anything to enhance one's own natural ability is cheating, full stop.” Compton also said that she decided to retire in March. You can read her full statement here. What's New in the 303: Boulder 70.3, Course Record Smoked, Electric Crowd, Close Women's Pro Race The male winner, Sam Long who grew up a few miles away, capped a perfectly imperfect day by setting a new course record. The temperature, cooler than predicted, helped keep the day from blowing up. The winds and smoke played havoc with some, but they ushered in many stories and memories on a course shared by a recent Olympian, top pro's and 2,500 age group athletes from all over the country. Emma Pallant-Browne won the women's race and moved up six spots in the PTO rankings making her an almost shoe-in for a captains pick (to be announced Thursday) for the upcoming Collins Cup. Not only did she take home $7,500 for winning Saturday, she will make at least $18,000 by making the European Collins Cup team. Olympian Taylor Knibb's debut performance at a 70.3 could hardly be called beginners luck finishing second, but she did learn a few things like needing to master the water cup grab; check out this interview with her. It will be interesting if she might be a captains pick for the Collins Cup even though her ranking puts her far out of the field (because she has been racing short, ITU races). https://www.youtube.com/watch?v=MgPCrcBc7eQ Triple Bypass August 21 Packet Pick-up Please being a facemask, just in case local requirements change for indoor activity. You must present your ID. If you are picking up for another individual, you must show a copy (or photo) of their ID. It is no longer possible to change your pickup location. Elevation Cycles Highlands Ranch - Aug 13th, 3 - 6 pm and Aug 14th 12-5 pm Wheat Ridge Cyclery – Aug 13th, 3-6 pm, 14th and 15th 12-6 pm Trek Boulder - Aug 14th and 15th 12-5 pm Evergreen Bicycle Outfitters - Aug 19 and 20th from 2-7 pm Startline - Aug 21 5-7am Aid Stations There are four aid stations along the Triple Bypass. All aid and support locations can be found on this handy Google Map. Juniper Pass 6:30am-10:00am Georgetown Overlook 8:00am-12:00pm Loveland Valley 10:00am-2:00pm Summit County Church 11:00am-5:00pm There will be a divine mix of sweet and savory snacks, including gluten-free and vegetarian options. Loveland aid will have Etai's sandwiches to power you through and Base Hydro will be on course throughout. Special appearance by Eggland's Best! Video of the Week: I Had a HEART ATTACK // Part 1 Closing: Thanks again for listening in this week. Please be sure to follow us @303endurance and of course go to iTunes and give us a rating and a comment. We'd really appreciate it! Stay tuned, train informed, and enjoy the endurance journey!

Taylor Knibb Boulder 70.3

303Endurance Podcast

Play Episode Listen Later Aug 14, 2021 76:30

This week we have one of the silver medalists from that very Olympic Mixed Relay, that's right pro triathlete, Olympian and Silver Medalist, not to mention 2nd place at her first IRONMAN 70.3 in Boulder this past weekend…Taylor Knibb. Show Sponsor: VENGA CBD Still loving the Venga CBD Super Sleep. It has Melatonin, CBD AND an all-new cannabinoid CBN that's been shown to promote sleep. You'll wake up well-rested and refreshed because Venga Super Sleep is all-natural and works with your body's systems to promote a great night's sleep. As with all of Venga CBD's products, Super Sleep is 100% THC-free and non-habit forming. Just go to https://vengaendurance.com/303podcast to order yours today. First-time order is 30% off with code (303PODCAST). We've also added 50% off your first month's subscription with code (303SUBSCRIPTION). In Today's Show Feature interview - Taylor Knibb Endurance News - Tim O'Donnell, Katie Compton What New in the 303 - Boulder 70.3; Triple Bypass next weekend Video of the Week - TO About His Heart Attack Interview Sponsor: UCAN Take your performance to the next level with UCAN Energy and Bars made with SuperStarch® UCAN uses SuperStarch instead of simple sugars to fuel serious athletes. UCAN keeps blood sugar steady compared to the energy spikes and crashes of sugar-based products. Steady energy equals sustained performance! You put in the training, so don't let nutrition limit your performance. Use UCAN in your training and racing to fuel the healthy way, finish stronger and recover more quickly! Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co Use the code 303UCAN for 20% off at ucan.co/discount/303UCAN/ or ucan.co, Interview with Taylor Knibb Taylor Knibb at 23, is the youngest woman ever to qualify for the U.S. Olympic Triathlon Team. She has been the USA Triathlon National Team's youngest member since she first made the team in 2017. Knibb was inspired to become a triathlete as a child after she watched her mom, Leslie Knibb, compete in an IRONMAN race and noticed the positive atmosphere. She tried a kids' race and was hooked on the sport from there, working her way through USA Triathlon's youth elite and junior elite pipelines. Up to this day, her favorite part of competing in triathlons is the camaraderie within the triathlon community, as well as the challenge of always growing and improving within the sport. In high school, she joined her school's cross-country team and swam for Nation's Capital Swim Club while continuing to compete in triathlons. She was named the Washington D.C. Gatorade Cross Country Runner of the Year and the D.C. State Athletic Association Runner of the Year in both 2014 and 2015. She was the 2015 and 2016 USA Triathlon Junior Elite national champion, the 2015 ITU Junior World Championships silver medalist, the 2016 and 2017 ITU Junior World Champion and the 2018 Under-23 World Champion— one of just three women ever to capture world titles at both the Junior and U23 levels. She also became the youngest woman to earn a spot on the podium at an ITU World Triathlon Series race in 2017, earning silver in Edmonton, Alberta, Canada. Knibb is a 2020 graduate of Cornell, where she ran NCAA track and cross-country for four years while balancing her elite triathlon career. She also joined the Cornell swim team her senior year. Today, Knibb trains in Boulder, Colorado, with Origin Performance Squad, an elite international training group coached by Ian O'Brien. Knibb considers the ITU Under-23 World Championships to be one of her favorite moments of her career because she accomplished a solid performance across all three disciplines. Elite Triathlon Career 2021: Won gold at the 2021 World Triathlon Championship Series Yokohama on May 15, qualifying for the 2020 U.S. Olympic Triathlon Team • Made her Olympic debut on July 27 in Tokyo, placing 16th in the women's individual event • Won a silver medal in the debut of Triathlon Mixed Relay at the Olympic Games, alongside U.S. teammates Katie Zaferes, Kevin McDowell and Morgan Pearson. Knibb is the youngest U.S. triathlete ever to win an Olympic medal. Our News is sponsored by Buddy Insurance. It's big time training and racing season. Buddy Insurance is the kind of peace of mind so you can enjoy your training and racing to their fullest. Buddy's mission is simple, to help people fearlessly enjoy an active and outdoor lifestyle. You can now get on-demand accident insurance to make sure you get cash for bills fast and fill any gaps between your current coverage. Go to buddyinsurance.com and create an account. There's no commitment or charge to create one. Once you have an account created, it's a snap to open your phone and in a couple clicks have coverage for the day. Check it out! Endurance News: Tim O'Donnell Heart Attack On March 12th, 2021 Tim suffered a heart attack during Challenge Miami. 80% of the main artery in his heart was blocked. Meaning he was only getting 20% of the blood he should have been to his heart. Called the Widow Maker as its the most lethal blockage. Its blockage of the LAD (left anterior descending artery) which is the main artery supplying the heart with blood. Katie Compton Receives a 4-Year Ban From Cycling for a Positive Doping Test Katie Compton has been banned from cycling for four years, retroactive to September 16, 2020, because of a positive doping test. In a statement, the cyclocross champion announced that she never knowingly took a banned substance, and she made the decision to retire back in March. Fifteen-time U.S. national cyclocross champion Katie Compton, 42, has received a four-year suspension on competition from the U.S. Anti-Doping Agency (USADA) after testing positive for a banned substance, the agency announced on August 11. Compton tested positive for an anabolic agent on an out-of-competition test taken on September 16, 2020. “Her urine sample was analyzed using a specialized test, known as Carbon Isotope Ratio testing, that differentiates between anabolic androgenic steroids (AAS) naturally produced by the body and prohibited anabolic agents of external origin. Anabolic agents have powerful performance-enhancing capabilities and can give an athlete an unfair advantage over fellow competitors,” the USADA statement explained. Compton's ban begins retroactively, from the day her positive sample was taken. That means all of her results, race points, and prizes received since September 16, 2020, are forfeit. Compton released a statement addressing the USADA's announcement. She said her results for that sample originally came back negative for any banned substances. USADA decided to re-test it after her Athlete Biological Passport (bio-passport) was flagged for an “irregularity.” The second test of the sample came back positive for an anabolic androgenic steroid, Compton said. “This news comes with great heartache and sadness, and it is the worst possible way to end my cycling career. I need to preface this news with the fact that I have always been a clean athlete, and I am proud of how much I have accomplished racing clean and being very careful with whatever I put into my body, especially after dealing with so many health issues throughout my life. I provided a sample for USADA in September 2020 that came back negative for any banned substances, it was not even atypical. That news was communicated to me in the same way it has always been via a letter from USADA. I've received that same letter after every test I've submitted for the last 19 years. In early February of 2021, after returning from a difficult race season, I learned that the same sample from September was re-analyzed due to a bio-passport irregularity and found to be positive for an exogenous anabolic steroid. This was devastating news to me as I have never intentionally or knowingly put anything like that into my body. I know how delicate women's hormones are, and I would never choose to take anything to jeopardize my health and, as a result, suffer irreparable damage to my endocrine system. And not only that, I never took anything for ethical and moral reasons; I've been a strong proponent of clean sport my entire career and feel doing anything to enhance one's own natural ability is cheating, full stop.” Compton also said that she decided to retire in March. You can read her full statement here. What's New in the 303: Boulder 70.3, Course Record Smoked, Electric Crowd, Close Women's Pro Race The male winner, Sam Long who grew up a few miles away, capped a perfectly imperfect day by setting a new course record. The temperature, cooler than predicted, helped keep the day from blowing up. The winds and smoke played havoc with some, but they ushered in many stories and memories on a course shared by a recent Olympian, top pro's and 2,500 age group athletes from all over the country. Emma Pallant-Browne won the women's race and moved up six spots in the PTO rankings making her an almost shoe-in for a captains pick (to be announced Thursday) for the upcoming Collins Cup. Not only did she take home $7,500 for winning Saturday, she will make at least $18,000 by making the European Collins Cup team. Olympian Taylor Knibb's debut performance at a 70.3 could hardly be called beginners luck finishing second, but she did learn a few things like needing to master the water cup grab; check out this interview with her. It will be interesting if she might be a captains pick for the Collins Cup even though her ranking puts her far out of the field (because she has been racing short, ITU races). https://www.youtube.com/watch?v=MgPCrcBc7eQ Triple Bypass August 21 Packet Pick-up Please being a facemask, just in case local requirements change for indoor activity. You must present your ID. If you are picking up for another individual, you must show a copy (or photo) of their ID. It is no longer possible to change your pickup location. Elevation Cycles Highlands Ranch - Aug 13th, 3 - 6 pm and Aug 14th 12-5 pm Wheat Ridge Cyclery – Aug 13th, 3-6 pm, 14th and 15th 12-6 pm Trek Boulder - Aug 14th and 15th 12-5 pm Evergreen Bicycle Outfitters - Aug 19 and 20th from 2-7 pm Startline - Aug 21 5-7am Aid Stations There are four aid stations along the Triple Bypass. All aid and support locations can be found on this handy Google Map. Juniper Pass 6:30am-10:00am Georgetown Overlook 8:00am-12:00pm Loveland Valley 10:00am-2:00pm Summit County Church 11:00am-5:00pm There will be a divine mix of sweet and savory snacks, including gluten-free and vegetarian options. Loveland aid will have Etai's sandwiches to power you through and Base Hydro will be on course throughout. Special appearance by Eggland's Best! Video of the Week: I Had a HEART ATTACK // Part 1 Closing: Thanks again for listening in this week. Please be sure to follow us @303endurance and of course go to iTunes and give us a rating and a comment. We'd really appreciate it! Stay tuned, train informed, and enjoy the endurance journey!

Ep 52: Requiem for a Dream

What's the Script?

Play Episode Listen Later Aug 12, 2021 50:21

Your wildest dreams have just come true! You're listening to What's the Script? the podcast where Stuart McPherson and Stephen Buchanan try to guess the plots of films they've never seen and this week they're trying to guess the plot of Darren Aronofsky's Requiem for a Dream. The movie might be bleak but this podcast episode isn't! Lots of fun to be had including - chat about recent cinema trips (The Purge and Space Jam), some out-of-sorts LAD banter and Mrs Alfridge has some things to say about Paddy McGuinness. Find us on Patreon.com/whatsthescript from just £3 to support the show and get access to twice as many monthly episodes and join in the fun of our "Stu & Steve Write a Film" adventure. You can follow us on Twitter @whatsthescript_, email us (a jpeg image of your face, or otherwise) on whatsthescriptpod@gmail.com and as always we'd love it if you left us a glowing 5 star review on iTunes too. Byeee!

2021/22 Pre-Season: Midfielders

Bang Average

Play Episode Listen Later Aug 8, 2021 58:59

Arguably the most important position in drafts this season, Mike and John delve deep into the middle of the field, including new Man City signing Jack the Lad, newcomer Jadon Sancho and mid-tier options like Rodri, Gilmore and Lingard

gilmore arguably lingard lad preseason man city rodri midfielders jadon sancho

The Gun Room: Episode 20

The Gun Room

Play Episode Listen Later Aug 6, 2021 13:58

The 2021 Barret Jackson Auto Auction in Las Vegas was one to remember. With a record-breaking $48 million in sales, it would seem that there is quite a market for unique automobiles. It has always intrigued me that in the auto world it seems that the items of the highest auction block value can be relatively new production cars or just as easily classics from 70 years ago. In this most recent auction, three wildly different autos broke the 1 million dollar ceiling. They were a 2015 Mclaren P1, a 1957 Mercedes 300SL Roadster, and a 2019 Ford GT. All amazing vehicles, feats of modern engineering and technology, lovingly cared for, and I'd imagine prized possessions of their owners. I am Joel Penkala and this is 10 Minutes on the Philosophy of Gun Restoration. You might be saying, what's this got to do with guns, but bear with me. From what I can gather, the McLaren and the Ford GT are likely original condition vehicles. The GT had 21 miles on the odometer so that's a safe bet. The 2015 McLaren probably had more miles, but chances are it was still near original. Now we come to the 1957 Mercedes 300SL. The Mercedes, though a stunning original example, is clearly no longer in original condition. I pulled a bit from the write up on the auction website “After a careful mechanical overview, new sway bar bushings and new motor mounts were installed, and the brakes were serviced, cleaned and adjusted. During the brake inspection, it was noted that there were no leaks and correct materials were used during restoration. Finished in the iconic 300SL color combination of DB 180 Silver Gray Metallic with a red leather interior. The silver paint was mixed with the correct metallic flake and was uniformly applied. The finish remains glossy and smooth with only light signs of use since the restoration.” I would argue that based on this single example (forgive the small sample size) that restored vehicles can and do command attention and dollars on the auction block. It seems though, in the world of classic firearms, a “restored” version commands a different value than one in “original condition” even if “proper finish and the correct materials” are used during restoration. I'll admit that I am looking at this question of gun restoration from the ruby lens of my own experience. I got into gunsmithing and have spent countless hours performing restoration services on my own guns. Dad and I were always looking for a ”gunsmith special”; a shotgun or rifle that was abused and misused, but still had the potential to be brought back. This desire was motivated by our own financial limitations, or I should say my financial limitations restricted what I could buy. Any gun in high condition was hard to justify. Not to mention they did not afford the opportunity to do what it was that we set out to do- work on guns. Tear them down, learn how they work. Fix parts, replace parts, make parts. We endeavored to find a project that represented a challenge and pitted our own abilities (pun intended) against these relics relegated to the parts pile. It would be hard to condemn us for what we did. The majority of our projects were inoperable, sold to us as ‘parts guns'. More than once I had to sign a paper that stated that I would not use a gun I was buying until I had it looked at by a competent gunsmith. But, in my reading, I would come to find that there was a contingent of folks in the gun world that seemed to question the philosophy of restoration. If they didn't, why was it so important that a Parker I looked at on gunsinternational was a “DelGrego restoration”. And why is that restoration deemed less valuable than an original gun? Perhaps I am a victum of my own desire, creating my own reality so to speak. I know that even in those early days I could recognize a ‘hack job' garage special. A replaced forearm that is clearly not to original spec. Maybe made of maple instead of walnut. Or an action that has been blued where the original was case color- or worse, spraypainted black. I'd like to think that the work we did was at the very least, in the image of the guns original condition. Sure I didn't have the ability to case harden the action on my single shot 20ga project. It was early in the Dad and Lad gunsmithign days, and heat treating was beyond our abilities at the time. Even still, we determined how to chemical color the action using some heat and products at our disposal. Is it truly original? No of course not, but the results provided created a gun that is far more pleasing to the eye. I have had the opportunity to hold a number of restorations, from a variety of talented folks. I do believe that if a restoration is completed in a way that remains true to how the guns were delivered from the factory, there is merit to this work. There is so much nuance to this process though, starting from knowing exactly what a gun looked like, from the factory. What shades and colors were produced by factory case hardening? Were the patterns striped or blotchy? Were the barrels a deep dark blue or were they more black? Shiny or a bit dull? What checkering patterns were used and what lines per inch were they? I am as guilty of this lack of knowledge as any other hack job garage smith. I don't necessarily know what the gun looked like when I start my work. Perhaps this is because I understand that my work will never be a true restoration in that sense. I am in the business of bringing a gun back from the grave. Perhaps, with a lifetime of practice, I could hone my skills to the level of factory original. At this point in time, I don't have the desire or inclination to replicate the work of the original craftsmen. My restorations are my own and will carry my mistakes and lack of abilities along with them. A field grade LC Smith, 12 gauge, with no case color, little blue, and checkering so worn that the lines are nearly gone carries little value. When the gun came to me it was inoperable. I am in the process of recutting the checkering, and to be honest, rather than sanding off what is clearly non-original lines, I am simply chasing what is there. This would be a travesty for some folks, and so it may be. It is my belief that this gun might have had a worse fate if it had not landed in my hands. A restored field grade LC does not carry the value to justify the cost (aka time) to do a proper restoration. Unless of course, the gun carries other value- sentimental value most likely- that might justify the expense. In my time working in a gunsmithing shop, there were several guns that came to us needing copious amounts of work, that would far exceed the value of the gun- restored or not. It was my job to explain to those folks that they were on the losing end of a deal, and to do so gently so as not to offend anyone's sensibilities. Typically the discussion would go about as I have laid out so far though the x-factor was always the history with the gun. Was it your fathers, or grandfather's? Had it been handed down over many generations? I saw guns that had been damaged at the hands of their current custodians. The guilt of damaging a family heirloom is a strong motivator to open one's wallet and spend the money required to make repairs. History and provenance always factor into perceived value. The Mclaren sold at the Barret Auction was owned by Deadmau5, a very successful DJ. I am sure that the celebrity history of the vehicle added to its value. The same way that a particular F Grade AH Fox Shotgun could sell for a whopping $862,500. Now, at the time of this podcast, William Larken Moore has a very fine 12 gauge AH Fox FE for sale- a Philly gun made in 1907. It's likely that you guessed what I am driving at- the difference between these two guns mechanically may be small, but the difference between these guns owners is very large indeed and reflected in their price. I suspect that the William Larken Gun was never owned by Teddy Roosevelt. For fun, I looked at the most expensive Fox on Gunsinternational. A $64,000 12 gauge Fox made for William Gough, serial number 6500. William Gough was an engraver himself and an engraver's son. He worked on Fox, Parker, Winchester, Remington, Marlin, Colt, Meriden, and Aubrey and is a celebrity of note in the gun world. The most interesting thing about this gun though - it is a copy. It has been upgraded and made to look like the original gun. This is noted in the Gunsinternational listing but brings up the not so pretty topic of fakes, imitations, humped-up guns. The underbelly of the gun world- and the art world, fashion world, car world, and so on. I do believe this is part of the issue folks have with restorations. For all but the well trained, a gun can be made to look original, or more than original, a Field Grade gun can be upgraded to a lettered grade. Or as is the case here, upgraded to mirror a gun with history- with provenance. And herein lies the bigger issue with restored guns. Its a catch 22 of sorts. A good restoration is one that brings the gun back to its original condition- as it was the day it left the factory. And the best restoration may pass as an original. The problem is when people take advantage of the fact that restorations can be done so well, it is nearly, if not completely impossible to tell the difference. It is worth noting that in Europe, particularly in England, it was commonplace to send your gun back to the maker for upkeep. They did not call this a restoration- primarily because the gun was returning to the maker- the original manufacturer - for reapplication of the original finish. Barrels were rebrowned or reblacked. Stocks were attended to- dings and dents steamed and removed, checkering pointed and oil finishes reapplied. Although I am sure there are original examples of guns from across the pond, it is clear that most guns were cleaned up over the years and the view of what it meant to have a gun in original condition is rather different than here in the states. Most guns here never made it back to the factory for refurbishing- either because the service was not offered or because the maker was no out of business. The complexities of the collector gun world abound. Original, restored, or upgraded, with provenance and celebrity status or not, guns like cars will always have a value that is not simply based on their mechanics. Upgrading a gun may be a gateway to have a facsimile of an original, at a fraction of the price, although like many human endeavors it is when nefarious intent clouds one's vision that this practice goes off the rails. It is one thing to upgrade a gun and represent it as such. It is completely different to upgrade a gun and/or knowingly misrepresent it as original. The world of firearms restoration is multifaceted, the idea of upgrading guns even more so. I believe that there is certainly a place for firearm restoration. The idea of bringing something back to life appeals to those of us who enjoy shotguns and rifles both in the field AND when they are apart on our bench. Not to mention the joy I find when I hunt with a gun that I have restored to function. There is something special in those moments afield, which for me, have been inextricably woven into the fabric of my life.

5 Cheap Growth Stocks with Top Rank

Zacks Market Edge

Play Episode Listen Later Aug 5, 2021 30:37

Ben Graham knew the PEG ratio was a powerful tool in value stock screening. (1:00) - Finding Stocks With Growth and Value (5:10) - Benjamin Grahams Hot Takes On Growth: Long Term Investing (13:50) - Tracey's Top Stock Picks (27:30) - Episode Roundup: ABG, GPI, LAD, CRMT, COG, ANF, ECHO Podcast@Zacks.com

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5 Cheap Growth Stocks with Top Rank

Value Investor

Play Episode Listen Later Aug 5, 2021 30:36

Ben Graham knew the PEG ratio was a powerful tool in value stock screening. (1:00) - Finding Stocks With Growth and Value (5:10) - Benjamin Grahams Hot Takes On Growth: Long Term Investing (13:50) - Tracey's Top Stock Picks (27:30) - Episode Roundup: ABG, GPI, LAD, CRMT, COG, ANF, ECHO Podcast@Zacks.com

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MLB DFS Strategy 8/4/21

Pitcher List Fantasy Baseball Podcast

Play Episode Listen Later Aug 4, 2021 43:49

Wednesday offers another packed night of baseball with 15 games featured all day to build daily fantasy baseball lineups on DraftKings and FanDuel. Join Greg Ehrenberg and Adam Scherer as they navigate the MLB DFS options on 8/4/21 for The MLB DFS Strategy Show. The guys will go game-by-game identifying the top plays of the day including Jose Altuve. Don't miss all of their top MLB DFS picks.Stream begins at 11:00 a.m. ET.Interested in sports betting? Check out our NEW Sports Betting YouTube Channel here: https://www.youtube.com/channel/UCDRCFbG3JeON668XOrIWq7Q/?sub_confirmation=1Early Slate - 0:00BAL (+215) @ NYY (9.5) - 28:04PHI (-105) @ WAS (9.5) - 34:42CLE (+175) @ TOR (9.5) - 37:30NYM (-155) @ MIA (7.5) - 41:10BOS (-150) @ DET (9) - 44:15LAA (-180) @ TEX (8) - 47:20KC (+210) @ CWS (8.5) - 52:30ATL (-115) @ STL (9) - 57:15CHC (+140) @ COL (11) - 1:00:57SF (-180) @ ARI (8.5) 1:04:30HOU (+185) @ LAD (9) - 1:09:10Awesemo's MLB DFS & Betting Strategy + ToolsMLB Props Tool: https://www.awesemo.com/mlb/mlb-player-props/MLB Betting Model: https://www.awesemo.com/mlb/mlb-power-rankings/MLB DFS Primer: https://www.awesemo.com/mlb/mlb-dfs/How To Win DFS Tournaments: https://www.awesemo.com/gameplan/how-to-win-at-dfs-tournaments/How To Use MLB Fantasy Cruncher https://www.awesemo.com/mlb/optimizing-your-mlb-dfs-process-with-fantasy-cruncher-the-fantasy-crunch/MLB DFS Projections: https://www.awesemo.com/mlb/mlb-dfs-projections-for-draftkings-and-fanduel/MLB DFS Rankings: https://www.awesemo.com/mlb/awesemos-mlb-rankings/MLB Ownership Projections: https://www.awesemo.com/mlb/mlb-draftkings-ownership-projections/MLB DFS Top Stacks: https://www.awesemo.com/mlb/mlb-dfs-top-stack-for-draftkings/MLB DFS Top Pitchers: https://www.awesemo.com/mlb/mlb-dfs-top-pitcher-for-draftkings/#MLBDFS #MLBNews #MLBLineups #MLBWeather #MLBDFSPicks #DraftKings #FanDuel #Picks #Awesemo #DailyFantasyBaseballFollow us onYouTube | http://awese.moe/youtubeTwitter | @Awesemo_Com | http://awese.moe/TwitterInstagram | @Awesemo_Com | http://awese.moe/TwitterFacebook | @AwesemoCom | http://awese.moe/IGFacebook Group | http://awese.moe/FBgroupApple Podcasts | http://awese.moe/podSpotify | http://awese.moe/SpotifyTwitch | http://awese.moe/Twitch

Mondialisation : le « dernier clou dans le cercueil » ? JACQUES SAPIR | YVES PEREZ

Sputnik France

Play Episode Listen Later Aug 3, 2021 50:40

Accusée d'aggraver les inégalités et le désastre écologique sur fond de pandémie mondiale, la globalisation économique et financière se voit mise en cause en différents endroits de la planète. La démondialisation est-elle déjà en cours ? S'agit-il d'une désoccidentalisation ? Marque-t-elle le grand retour du politique sur le technique ? À l'occasion de la réédition de « La Démondialisation » de Jacques Sapir (Seuil/Points, 2021), Russeurope Express reçoit Yves Perez, économiste, professeur émérite de l'Université catholique de l'Ouest à Angers et auteur des « Vertus du protectionnisme » (L'Artilleur, 2020). Une émission produite et co-animée par Clément Ollivier. Retrouvez tous les numéros de #RusseuropeExpress sur le site de Sputnik : https://fr.sputniknews.com/radio_sapir Abonnez-vous au podcast pour ne jamais manquer un épisode : ▶ iTunes : https://podcasts.apple.com/fr/podcast/russeurope-express/id1460834246 ▶ Google Podcasts : https://podcasts.google.com/?feed=aHR0cHM6Ly9mci5zcHV0bmlrbmV3cy5jb20vZXhwb3J0L3JzczIvcG9kY2FzdC9yYWRpb19zYXBpci8%3D ▶ Spotify : https://open.spotify.com/show/3myZ9T0TgFs38kWzso3mai ▶ Deezer : https://www.deezer.com/fr/show/363002 ▶ SoundCloud : https://soundcloud.com/sputnik_fr/sets/russeurope-express ▶ Ou copiez l'adresse du flux RSS dans votre application de podcast : https://fr.sputniknews.com/export/rss2/podcast/radio_sapir/

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ITD 23 - Splashes and Ripples

Play Episode Listen Later Aug 2, 2021 87:38

With about 2 months remaining in the regular season, Shwebsi and Jordan reconvene to discuss the big splashes that teams made at the trade deadline, and the subsequent ripple effects that will be felt in your deep leagues during the home stretch. Timestamps: Quick hits: Bradley Zimmer (3:53), Rodolfo Castro (4:20), Giants love (5:30), Tyrone Taylor (8:21), Brendan Rodgers (9:38), Luis Arraez (10:22), Luis Patino (11:52), Tanner Houck (15:28) Team-by-team deep league trade ripples: ATL (18:01), ARI (19:34) , BAL (21:06), BOS (21:55), CHC (24:23), CWS (29:35), CLE (30:59), COL (34:35), DET (36:40), HOU (37:50), KC (41:28), LAA (43:39), LAD (46:02), MIA (47:32), MIL (51:47), MIN (54:17), NYM (56:49), NYY (59:04), OAK (59:57), PHI (1:02:03), PIT (1:03:46), SDP (1:05:55), SFG (1:08:28), SEA (1:10:26), STL (1:14:04), TB (1:14:40), TEX (1:17:28), TOR (1:19:03), WSH (1:19:52) ---- If you want to join us as we prep and record the podcast LIVE every Sunday night, join us starting at 9:00 pm EST over on twitch.tv/shwebsi. We may even answer your question or give you a shoutout live on the show! Be sure to follow us on Twitter @InTheDeepPL, and feel free to send any mailbag questions to inthedeeppl@gmail.com. Follow us each individually on Twitter: Chris - @Shwebsi Jordan - @BuntSingles Get PL+ and join our Discord: https://pitcherlist.com/plus

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Giants Recap

Astros Baseball

Play Episode Listen Later Aug 2, 2021 14:58

This episode covers the Giants series , standings, matchup vs LAD, and more. Brought to you by Ram Shirts and Dugout Mugs --- Send in a voice message: https://anchor.fm/astrosbaseball/message

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7/30/21 Dodgers vs. Diamondbacks FREE MLB Pick

PlaybyPlay

Play Episode Listen Later Jul 30, 2021 0:43

LA Dodgers vs. Arizona Diamondbacks MLB Pick Prediction 7/30/2021 by Tony T. Dodgers at Diamondbacks—MLB free pick is LA Dodgers on the run line -1.5 runs at -115. Getting the start for LAD will be Tony Gonsolin. The righthander has allowed one earned run or fewer in seven of his eight starts. He allowed two earned runs in two starts against the Diamondbacks this year working 7 2/3rd innings. Zac Gallen the starter for the Diamondbacks. He did deal with an in season injury. Past three starts righthander allowed eleven earned runs in 11 2/3rd innings. Huge step down in class for LAD after facing the Giants on the road for a three game series. Diamondbacks bullpen has struggled at home with an ERA 5.18, WHIP 1.52 and opponents batting average .288. Play LA Dodgers run line -1.5 runs at -115.

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250 MEXICO: Er Cancún for amerikaniseret?

Radiovagabond med Palle Bo fra rejse hele verden rundt

Play Episode Listen Later Jul 28, 2021 25:45

Hola fra Cancún, Mexico I denne episode besøger jeg et af de mest turistede steder i Mexico: Cancún på den Caribiske kyst i landet. Lad os starte med svaret på et spørgsmål, du meget vel kan få stillet i en pub-quiz på et tidspunkt: Hvad er tættest på Cuba – Key West i Florida eller Cancún her i Mexico? Hvis du kigger på et kort, kan man forledes til at tro, at det er Cancún. Men det er faktisk ikke tilfældet. Key West er 151 km fra det tætteste punkt af Cuba, og Cancún er 206 km fra øen. Skål… og selv tak! Efter jeg næsten aldrig havde fundet ud til den rigtige gate i Monterrey. fordi alle skilte og højttalerudkald kun var på spansk, befandt jeg mig på flyet og sippede til en kølig Cuba Libre – for at komme i den rigtige stemning. Og kort derefter kunne jeg kigge ned på mit kommende hjem med hvide strande, palmer og et azurblåt hav. Og jeg kunne ikke vente med at komme ned på jorden og udforske stedet, der tiltrækker vildt mange amerikanere og efterhånden også en masse europæere. TOUCHDOWN I CANCÚN De to første ting, der var på min liste over ting at foretage mig i Cancún var at komme ud at dykke, og besøge et kunstmuseum. Mit største problem var, hvad jeg skulle foretage mig først (#firstworldproblems). Jeg kløede mig i nakken og besluttede mig for at gøre begge dele – på samme tid. Men først… 7 OVERRASKENDE FAKTA OM CANCÚN Du brænder ikke fødderne på strandsandet Du ved, hvordan man ofte brænder fødderne, når man går rundt på en tropisk sandstrand. Det kommer ikke til at ske her i Cancún. Sandet på den 20 km lange hvide sandstrand er faktisk ikke sand. Det er knuste koraller, som ikke bliver varme som sand – selv i høj solskin. Der boede kun tre mennesker her Cancún er en kæmpe turistmagnet, der tiltrækker hele 700.000 mennesker hvert år. Det er næsten lige så mange, som der bor her. I dag har Cancún et befolkningstal på 888.797 mennesker, men det har bestemt ikke været tilfældet altid. Så sent som 1979 var det officielle befolkningstal 3. Ikke 3000. Ikke 300. Nej kun tre mennesker. Nu er det altså ganske anderledes. Byen har 4674 hoteller og omkring 30.000 hotelværelser. Cancún har et kæmpe mexicansk flag Hvis du er i den pulserende hotel-zone, vil du bemærke et enormt stort mexicansk flag – eller som de kalder det her gran Bandera Mexicana. Det er fremstillet af det samme stof, der bruges til at lave faldskærme, nok for at gøre det lettere, men det er nu stadig ret tungt. Selve flaget vejer 228 kg og det krævede 40 bomstærke mexicanske soldater at trække det op i en 105 meter høj flagstang. Du kan opleve lignende kæmpeflag i andre mexicanske byer, som en del af et program, der blev startet i 1999, som de kalder “banderas monumentales”, spansk for ”monumentale flag”. Stranden forsvandt efter en orkan Da Orkanen Wilma ramte Cancún i 2005 blev 12 km af stranden helt ødelagt. Den forsvandt – og Cancún uden en strand er ikke helt den samme turistattraktion. Derfor blev der kastet meget tid og penge i at få den genskabt fra 2009-2010. De trak ubegribelige mængder sand op fra havbunden og det kostede næsten 450 millioner kroner at genskabe den smukke strand. Skildpadderne kommer hjem lægger æg på stranden Hvert år I maj vender tusindevis af skildpadder tilbage til, hvor de selv kom til verden, for at lægge æg på stranden i den populære hotelzone her i Cancún. Heldigvis gør både hotelejere, medarbejdere og selv turister en masse for at passe på at deres reder og æg ikke kommer noget til. Så hvis du kommer i maj, så vær forberedt på at store dele af stranden er spærret af, for at padderne kan få lidt privatliv. Svøm med tonsvis af hvalhajer Mellem maj og september har du muligheden for at opleve tonsvis af hvalhajer. Bogstaveligt. Nogle af dem er så store som busser, men de er ganske harmløse, og vil gerne lade dig tage på en svømmetur med dem. Verdens næststørste koralrev er her Vi kender jo alle Australiens berømte Great Barrier Reef som den største koralrev i verden. Men nummer to er lige her: Maya Barrier Reef er det næststørste koralrev i verden og en af Cancúns største attraktioner. Enestående marineliv, smukke koraller og krystalklart turkisblåt vand. Fantastisk til snorkling og dykning. CANCÚNS KUNSTMUSEUM PÅ HAVBUNDEN Apropos dykning, så er det noget, jeg nyder utroligt meget. Derfor gik jeg på jagt efter en dykkeoplevelse, kort efter jeg ankom. Jeg fandt en – som ovenikøbet samtidig er et besøg på et kunstmuseum. To fluer med ét smæk. Takket være den kreative britiske skulptør, Jason deCaires Taylor og fem dygtige mexicanske kunstnere, så det berømte Cancún Underwater Museum dagens lys – eller rettere havets bund mellem Cancún og Isla Mujeres. Det er en masse skulpturer, der får en til at gispe efter vejret, så det var godt, at jeg var udstyret med en tank på ryggen med rigelig luft. Museet består af mere end 500 skulpturer i naturlig størrelse, hvilket gør det til en af de største og mest imponerende undervands kunst-installationer i verden. Da jeg var blevet registreret på dykkercentret, fik jeg muligheden for at sludre lidt med de andre, jeg skulle dykke med. Mine ”diving-buddies”. Cancún Underwater Museum er en blanding af skulpturer, fra en gruppe personer, der står i en cirkel og kigger mod himlen, en gruppe mænd, der ligger på knæ med hovedet begravet i sandbunden, til to skulpturer med en ny og en gammel Boble-Folkevogn. Men måske det mest imponerende var en gruppe på næsten 450 beton-mennesker i naturlig størrelse, der stod sammen i en stor gruppe. Det var så syret og næsten uhyggeligt at svømme rundt om dem og over dem – sammen med farvestrålende fisk, søstjerner og skildpadder. Mange af skulpturerne har smuk koral voksende på dem, og faktisk var en af grundene til at de lavede det også for at beskytte koraller. Man ville lave et andet sted, at dykke, så det nærliggende koralrev bliv skånet en smule. For at få skulpturerne ned på havbunden uden, de kom noget til, måtte de have en 40 ton special-kran placeret på en færge. Herfra blev de langsomt sunket ned på havbunden og placeret de rigtige steder. Det hele er lavet i pH-neutral marine-cement, og efter de blev lavet på landjorden, blev de renset grundigt, så der ikke var kemikalier, der kunne skade vandet, dyrelivet eller korallerne. Der er tænkt på det hele, og det var virkelig imponerende – og er et ”must-see”, hvis du har dykkercertifikat. Og hvis ikke, så kan du stadig se en del på en snorkeltur eller fra en båd med glasbund. Men dykning er den bedste made at opleve det – og jeg var næsten i trance, mens jeg svømmede rundt dernede. Det er den mest surrealistiske dykkeoplevelse, jeg har haft til dato. ISLA MUJERES Isla Mujeres (kvinde-øen) er et andet fantastisk sted at besøge, hvis du er i Cancún. Den lille søvnige (men også livlige) ø, er blevet ret populær de seneste år. Perfekt for en dagstur. Den er blot en 20 minutters færgetur fra Cancún, hen over skulptur-parken. Et par dage efter mit dyk, sprang jeg på færgen sammen med en god ven, som var taget hertil fra Danmark for at opleve det sammen med mig. Straks da vi sætter fødderne øen løber vi på José. En af de lokale, som meget gerne vil sælge en oplevelse eller to til os. Og naturliglig vis er det ”special price for you, my friends”. Vi bed på og efter morgenmad, gik vi tilbage til José og købte en snorkeltur til 125 kr. pr. person. Prisen på skiltet var 220 kr. pr. person, så enten fik vi en god pris, eller også er de bare smarte og laver skilte med højere priser. Du kan gøre det samme: Hoppe af færgen og finde en José eller to. Eller også kan du kigge på denne TripAdvisor-liste med masser af forslag. Isla Mujeres er en smuk, stille tropeø, hvor tingene kører lidt langsommere end i Cancún. Øen er kun 8 km lang og 600 meter på det bredeste punkt. Selve byen, man ankommer til, er ganske lille (kun 4x6 gader) og nem at udforske til fods. Men selvom den er lille, er der masser at foretage sig. Du kan bruge dagen på aktiviteter i vandet, shopping, udforske og måske møde nye venner. BILLEJE FRISTRATIONER Efter at være kommet tilbage til Cancún, planlagde vi at besøge en anden populær seværdighed i området. Men da det er lidt udenfor byen, havde jeg besluttet at leje en bil. Det er noget, jeg gør ofte, og for det meste noget, der er meget nemt. Men ikke her. Jeg havde bestilt og betalt for billejen online, og da jeg kom for at hente den startede forvirringen. De ville have, at jeg skulle betale stort set det samme en gang mere for en forsikring, jeg ikke havde brug for. Jeg var der en et par timer, men til sidst lykkedes det, og dagen efter trillede vi vestpå mod de fantastiske Maya-ruiner ved Chichen Itza, med mexicansk radio i højttalerne. Inden vi kom helt derud, stoppede vi for at få en kop kaffe, og her lod vi os besnakke til at købe en pakkeløsning, som inkluderede parkering, frokost og billetter til templet – noget, der sparede os både penge og en masse tid i lange køer. BESØGER MAYA-RUINER VED CHICKEN ITZA Chichen Itza er et af de mest besøgte arkæologiske steder i Mexico – hvert år besøgt af 2,5 millioner. Du kan komme dertil fra Cancún med bil, bus eller ved at booke en tur-pakke. Det er bare 200 km vest for Cancún. Du kan oversætte Chichen Itza fra mayasprog til ”Ved kanten af brønden, hvor de vise mænd fra havet bor”, og det blev betragtet som en af de vigtigste bystater i Amerika, i tiden før den spanske invasion. I dag er det meget kendt for et sted med velbevarede ruiner, og endnu mere kendt efter det blev valgt som et af de New 7 Wonders of the World i 2007. Chichen Itza er opdelt i to dele: Gamle Chichen og Chichen Itza, og du kan se i alt 26 maya ruiner. Jeg mødte en maya fyr ved navn Santos, som faktisk kunne tale sproget. Han lærte mig at sige ”hvad koster det” på mayasprog, hvilket var praktisk at vide i dette område med mange boder. Den store pyramide, som kaldes El Castillo, er den mest imponerende maya bygning her på stedet. Dette tempel dominerer midten af området. Mens jeg gik rundt om pyramiden bemærkede jeg en meget underlig lyd. Når man står et bestemt sted og klapper kommer der et meget besynderligt ekko tilbage. Naturligvis optog jeg det, så lyt nu til episoden, hvis du ikke allerede har gjort det. Det koster 170 kr. for voksne og 25 for børn, at komme ind i dette UNESCO World Heritage site. Måske er det en god investering at bruge en smule mere på at have en guide ved din side. Eller du kan gøre som jeg gjorde: Stoppe for at få en kop kaffe inden du ankommer, og lytte til, hvad de prøver at sælge dig. Måske er det en god løsning, de tilbyder dig. IS CANCÚN FOR AMERIKANISERET? Jeg har hørt folk sige, at Cancún er så overrendt af amerikanere, at det ikke er ”det rigtige Mexico”. Ja, Cancún er berygtet for at være ret ”amerikaniseret”, men hvis du spørger de lokale, siger det, at det blot er en anden side af Mexico. Mexico er et stolt og meget mangfoldigt land, så tag det med et gran salt, når folk siger, at ”Cancún ikke er det rigtige Mexico”, for det er det. Det er lige så rigtigt som andre dele af landet. Jeg har tilbragt noget tid i Monterrey uden mange turister, og så oplevet noget helt andet her i Cancún, og jeg er glad for at jeg fik oplevet begge sider af Mexico. Men jeg er slet ikke færdig med dette land, så jeg kommer tilbage. NEXT STOP: FLORIDA Nu tager jeg til Florida, hvor jeg vil besøge Key West, Miami, Naples, Orlando og et par andre steder. Det bliver i den sidste episode i denne sæson. Mit navn er Palle Bo og jeg skal videre. Vi ses.

Comics with Umar Ditta

Nerds, Geeks, and the Kitchen Sink

Play Episode Listen Later Jul 26, 2021 94:54

Comics writer Umar Ditta joins DK and Chris for a great chat about Umar's fantastic work on Untethered and Lad. We had a small amount of technical issue with the sound so be gentle, but the episode is perfectly listenable, we think! The show finishes off with a very fun comics pitching session. Which fantasy comic idea would you most like to see? Let us know! Get Umar's comics over at: https://umarditta.gumroad.com/ or https://t.co/JDFjAAvfpX?amp=1 @umarditta on Twitter to stay up to date on what Umar is working on Join our Discord and chat with us and other listeners!: discord.gg/mHQZd47xvy Get us on Twitter @geekssinks @dkrefft and @cdstein69 Like us on Facebook and get into the conversation! Email us at nerdsgeekssinks@gmail.com Check out our online store for MERCH! www.redbubble.com/people/nerdsgeekssinks

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Where to Find the Best Stock Deals Right Now

Zacks Market Edge

Play Episode Listen Later Jul 22, 2021 33:53

These companies have some of the lowest P/Es among the Zacks Rank Strong Buy stocks. (1:00) - Finding Cheap Stocks In A Beaten Down Market (7:15) - Tracey's Top Stock Picks (22:45) - Bonus Stocks To Keep On Your Radar (28:30) - Episode Roundup: OROVY, SWBI, KBH, CWH, WGO, DKS, HIBB, VSTO, WTI, DOW, LAD, PAG, GPI

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Where to Find the Best Stock Deals Right Now

Value Investor

Play Episode Listen Later Jul 22, 2021 33:53

These companies have some of the lowest P/Es among the Zacks Rank Strong Buy stocks. (1:00) - Finding Cheap Stocks In A Beaten Down Market (7:15) - Tracey's Top Stock Picks (22:45) - Bonus Stocks To Keep On Your Radar (28:30) - Episode Roundup: OROVY, SWBI, KBH, CWH, WGO, DKS, HIBB, VSTO, WTI, DOW, LAD, PAG, GPI Podcast@Zacks.com

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Liam Mitchell- Announcement

What a Lad

Play Episode Listen Later Jul 18, 2021 23:36

One of NZ rugbys biggest names is off! Liam Mitchell the Hurricane and Manawatu Turbo legend, has decided to head off shore with a deal that no one saw coming. He tell's all exclusively to the What a Lad podcast just because he is an absolute lad. Many of you will already know the Liam Mitchell story from his What a Lad episode in season 1, where he shared is journey from being in the 4th XV at school, to becoming the leader of the Manawatu Bucketheads and then becoming an official Turbo the following year! Now the great lad known as Chippy is off to ply his trade in Italy but as you'll hear thats about as much as he knows of the deal. It's always good getting good lads on the podcast, if you enjoy this episode then please give it share it's very much appreciated.

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Why Megalodon Was So Huge, Misophonia in the Brain, Trivia

Curiosity Daily

Play Episode Listen Later Jul 16, 2021 13:58

Learn about how huge Megalodon was and why some people have misophonia, a severe hatred of sounds. Plus: a trivia game! Dive deeper into all your favorite Shark Week shows with Shark Week's Daily Bite Podcast hosted by Luke Tipple: Listen on Apple Podcasts: https://podcasts.apple.com/us/podcast/shark-weeks-daily-bite/id1527053422 Listen on Spotify: https://open.spotify.com/show/0dfzM1ktSB1mSKD5z4Qujm?si=R8rNBksMRS-JrgMs9JIJ5g&dl_branch=1 Learn more: https://www.discovery.com/shark-week/everything-you-need-to-know-about-the-daily-bite-podcast Please vote for Curiosity Daily in the 2021 People's Choice Podcast Awards! Register at https://podcastawards.com, select Curiosity Daily in the categories of Education and Science & Medicine, and then click/tap "save nominations" at the bottom of the page. Voting in other categories is optional. Your vote is greatly appreciated! Here's just how huge Megalodon was by Grant Currin Body size of the extinct Megalodon indeed off the charts in the shark world. (2020). EurekAlert! https://www.eurekalert.org/pub_releases/2020-10/tfg-bso092120.php ‌Body, jaw, and dentition lengths of macrophagous lamniform sharks, and body size evolution in Lamniformes with special reference to “off-the-scale” gigantism of the megatooth shark, Otodus megalodon. (2020). Historical Biology. https://www.tandfonline.com/doi/full/10.1080/08912963.2020.1812598?scroll=top&needAccess=true ‌Fletcher, T. (2021, January 11). Giant ancient sharks had enormous babies that ate their siblings in the womb. The Conversation. https://theconversation.com/giant-ancient-sharks-had-enormous-babies-that-ate-their-siblings-in-the-womb-152903 ‌Baby Megalodons Were 6-Foot-Long Womb Cannibals, Study Suggests. (2021). The New York Times. https://www.nytimes.com/2021/01/10/science/megalodons-baby-shark.html Episodes referenced in Curiosity Challenge Trivia game: Skipping stones: https://omny.fm/shows/curiosity-daily/stress-during-pregnancy-might-affect-the-babys-sex-skipping-stones-overspending Bats: https://omny.fm/shows/curiosity-daily/bats-map-the-world-by-time-not-distance Things we overlook: https://omny.fm/shows/curiosity-daily/why-we-always-forget-that-less-is-more-leidy-klotz-subtract-the-untapped-science-of-less A severe hatred of sounds may come down to a sensitive brain connection by Kelsey Donk Supersensitive connection causes hatred of noises. (2021). EurekAlert! https://www.eurekalert.org/pub_releases/2021-05/nu-scc052421.php Kumar, S., Dheerendra, P., Erfanian, M., Benzaquén, E., Sedley, W., Gander, P. E., Lad, M., Bamiou, D. E., & Griffiths, T. D. (2021). The motor basis for misophonia. The Journal of Neuroscience, JN-RM-0261-21. https://doi.org/10.1523/jneurosci.0261-21.2021 Follow Curiosity Daily on your favorite podcast app to learn something new every day withCody Gough andAshley Hamer. Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers. See omnystudio.com/listener for privacy information.

Sexy Wittig

Camille

Play Episode Listen Later Jul 15, 2021 50:04

Elle s'appelait Monique. Lesbienne, écrivain, militante et une des fondatrices du MLF, elle n'apparaissait pas aux côtés de ses contemporaines au Panthéon des féministes françaises. Jusqu'à ce que la quatrième vague du féminisme et le militantisme sur les réseaux sociaux portent aux nues sa pensée politique. Qui était celle qui a un jour affirmé que « les lesbiennes ne sont pas des femmes » ? Dans cet épisode hors-série, enregistré en direct et en public au Binge Audio Festival, Camille Regache reçoit la documentariste radio Clémence Allezard, qui a signé pour l'émission de France Culture « Une vie, une oeuvre » le portrait d'une guerillère qui l'obsède, « Monique Wittig, (1935–2003), écrivain et lesbienne révolutionnaire ». POUR ALLER PLUS LOINLes travaux de Clémence Allezard, notamment « Sortir les lesbiennes du placard », La Série Documentaire (France Culture, 2019), « Violé·es : une histoire de dominations », La Série Documentaire (France Culture, 2021). Pour comprendre la pensée théorique de Wittig, l'épisode « Contraint·es à l'hétérosexualité » un épisode avec Ilana Eloit (Camille, Binge Audio, 2019). L'article « Wittig n'était pas une femme » signé Ilana Eloit dans La Déferlante (numéro 2, 2021). Pour découvrir les Gouines Rouges, le magazine lesbien Well well well (numéro 3, 2016). RÉFÉRENCES CITÉESMa soeur sauvage (Gille Wittig, 2008), L'Opoponax (Monique Wittig, 1964), Les Guérilleres (Monique Wittig, 1969), Le corps lesbien (Monique Wittig, 1973), Le voyage sans fin (Monique Wittig, 1985).CRÉDITSCamille est un podcast de Binge Audio animé par Camille Regache. Cet épisode a été enregistré le 10 juillet 2021 lors du Binge Audio Festival à Wonderland (Paris, 12e). Musique : Solène Moulin. Prise de son et réalisation : Mathieu Thévenon. Production : Lorraine Besse et Anaïs Daïkha. Edition : Camille Regache. Identité graphique : Sébastien Brothier (Upian). Direction des programmes : Joël Ronez. Direction de la rédaction : David Carzon. Direction générale : Gabrielle Boeri-Charles. See acast.com/privacy for privacy and opt-out information.

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Manhunter with Umar Ditta

The Best Little Horror House in Philly

Play Episode Listen Later Jul 12, 2021 104:31

It's just you and me now, sport.... because we're profiling Michael Mann's Manhunter, man! Author of Lad: the Homecoming and the commissioner of cozy Umar Ditta is here and we're discussing Mann's expressionist approach to rejecting realism, Heat being the Paddington 2 of 1995, David Lynch's potential direction and wondering... what if Bane was in Manhunter? This and more only on the Best Little Horror House in Philly! Check out the patreon at Patreon.com/littlehorrorphl to get bonus episodes and more, and send in questions and the like to bestlittlemailbag@gmail.com!

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DC Pride 2021 Celebration - Part 2 (feat. DC Pride #1's creators)

Gotham Outsiders: A Batman Bookclub

Play Episode Listen Later Jul 12, 2021 47:31

In this special episode of Gotham Outsiders: A Batman Bookclub, we celebrate DC Pride #1 with creators from the issue: Steve Orlando, Luciano Vecchio, Ariana Maher, and Enrica Eren Angiolini. Steve: @thesteveorlando (Twitter), @the.steve.orlando (Insta) Luciano: @LucianoVecchio (Twitter), @lucianovecchioart (Insta) Ariana: @CommentAiry Eren: @ErenAngiolini Chris: @themythofpsyche TJ: @troyfin2 Gotham Outsiders: @GothamOutsiders Music and edited by: Nick Oyler Logo: Aliza Layne

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Give God Your Lunch

Hopewell Baptist Church

Play Episode Listen Later Jul 11, 2021 35:32

Below is a excerpt from the sermon... John 6:1–11 “After these things Jesus went over the sea of Galilee, which is the sea of Tiberias. 2. And a great multitude followed him, because they saw his miracles which he did on them that were diseased. 3. And Jesus went up into a mountain, and there he sat with his disciples. 4. And the passover, a feast of the Jews, was nigh. 5. When Jesus then lifted up his eyes, and saw a great company come unto him, he saith unto Philip, Whence shall we buy bread, that these may eat? 6. And this he said to prove him: for he himself knew what he would do. 7. Philip answered him, Two hundred pennyworth of bread is not sufficient for them, that every one of them may take a little. 8. One of his disciples, Andrew, Simon Peter's brother, saith unto him, 9. There is a lad here, which hath five barley loaves, and two small fishes: but what are they among so many? 10. And Jesus said, Make the men sit down. Now there was much grass in the place. So the men sat down, in number about five thousand. 11. And Jesus took the loaves; and when he had given thanks, he distributed to the disciples, and the disciples to them that were set down; and likewise of the fishes as much as they would.” Father, would You bless now, this time we have? Just a little bit of time, a lot of preparation. Some people have traveled an hour just to get to church. Some single parents got some kids ready all by themselves just to get here. Bus drivers drove buses, people cleaned buildings, choir and special music rehearsed. Thank You for all the labor., and here we are — we've got a few minutes to talk about Your Word. It's miracle-working. Do a miracle in our hearts today. Lord, I pray that you would feed us just like You fed these hungry people years ago. In Jesus' name, we ask, Amen. I have been on this mountain where this miracle took place… not during the time of the miracle(!), but it's that place many of you saw on the Israel trips we've taken. They call that the Hill or the Mount of the Loaves and Fishes. The Catholic church has actually built a building over the place where the lad handed the lunch to Jesus, or so they say. Like they know that was the exact place. Who knows? But what a wonderful miracle took place on this hillside. You say, Pastor, what's the background to the story here? It said, “after these things.” So, what had happened? Jesus, of course, Who had been born in Bethlehem — it's 30 years later, and He turns water into wine. And word starts getting out. This Guy is a miracle worker. In John 4, He heals someone. Remember, the woman at the well? He heals her soul, and she tells the whole city. In John chapter 5, a man is laying at a pool, and Jesus reaches down and tells him to pick up his bed and heals him. Now all these things are starting to get out. Good news back then traveled fast. And so, they had heard about Jesus raising the dead, healing, the blinded eyes, healing the cripple, and word had come out. So now everywhere Jesus went there were multitudes. He was like a rock star. It was like when a famous politician — when news got out, they wanted to be there and maybe see a miracle. Not only that, they wanted to hear him speak. One of the guards said, “No man ever spoke like this before.” And sometimes Jesus would hold people spellbound for three days. They wouldn't leave. They wouldn't eat. They just sat there and listened to His words. By the way, that's part of what's going to happen up in Heaven. We'll get to sit at His feet and hear Him speak, and He'll know your name. He'll know all about you, and we will never have to leave His presence. So, now the crowds are starting to come. Jesus and his disciples get off the boat. Now they're heading up the hill. Thousands of people — men are stopping their jobs: They're stopping their pottery. They're not watching the sheep. They're stopping their construction. They're heading up, taking the days off work. They're just mobbing Jesus. And there's a little lad the story. The Bible doesn't give his name. “Lad” probably means he wasn't quite a young man. He could have been in 5th or 6th grade, maybe young junior high. He was simply called “a lad.” No name, but he was in the crowd. I can imagine him coming to his mother that day saying, “Hey mom, can I have off school today? I hear Jesus is in town. I want to hear Him, and I want to see Him do a miracle.” His mom, being like most moms, probably would have said, “No, you have school today.” “Well, I heard the disciples can sign off for us, and we can get an excuse. The disciples will sign, and it'll be like a field trip. You know, this is like history, mom.” “Okay, I'll let you go. How long you're going to be gone?” “I don't know. Jesus talks for a long time. Maybe I can stand in line and get His autograph or get a little selfie. Maybe someone would draw a picture of us together or something. Mom, I just want to stay all day.” And I imagine the mom probably at that time said, “Well you're going to need a lunch.” And I imagine the boy said, “Mom, I don't want to bring a lunch. No one else is bringing a lunch.” Son, I don't want you to be hungry. No son of mine is going to starve while he's watching Jesus preach.” And so, he had a little lunch, and he goes. The Lord I want to just give you several thoughts about the story quickly. Number one, we see the Lord. The Bible said, “He saw that the people were hungry.” I want to say this: He sees your need. Maybe no one knows what you need this morning, but Jesus sees it. Jesus sees past the eyes. He sees past the outside. He sees past the hurts. He sees past all that, and He sees this is something they need. The word love simply means seeing a need and meeting it. And that's what Jesus does.

#139 - Les bons comptes font les bonnes féministes