Podcasts about ap1

Our picks for the top 10 best sounding speakers from the past 12 months. Marc and Brian rundown their best speaker picks from cheapest to most expensive. In preparation for the upcoming AXPONA show in Chicago, the pt.AUDIO staff presents some of the best speaker listens since the last show. Much has been updated, revealed and redeemed. Also don't forget to check out the show sponsor of this episode: Tidal Audio and The Voice That Is along with Audio Ultra and Artisan Fidelity will be at the Chicago Marriott Schaumburg April 11th and 12th from 10am to 5pm where they will feature three big rooms and the world premier of the new AP1 speaker. Also available for a listen will be the Contriva G3 and Piano G3 speakers, the new Ferios G2 mono amplifiers, the Contros Digital Music Converter, the Prisma preamplifier, TIDAL x Bugatti MP1 and MC1 electronics, Turnbull Audio Cables and more. Season 12 Merch is now available! The pt.AUDIO Record Weight In Walnut : 230 Gram S12E3 Sponsors: NORDOSTdotCOM - A Clear Choice For The Best Connection SCHIITdotCOM - Audio Components Designed & Built in Texas, Starting At $49 AXPONAdotCOM - North America's Audio Expo ZMFHEADPHONESdotCOM - Traditional Craft, Modern Acoustics

Denna fredags Börslunch fokuserar på det som talar för Europa och Sverige, samt investeringar som kommer gynna tillväxten. Men vilka fler möjligheter finns det för Sverige och dess industri? Europa och dess börser har levererat starkare än USA sedan valet.Kommer ljusglimtar i arbetsmarknaden och industrin bli större eller är nu USA:s ekonomi går in i en övergångsperiod? I studion gästar Danske Banks senior strateg Maria Landeborn och Martin Nilsson, förvaltare på AP1.

In part 1 of this episode, we explore the Global Asset Owner Peer Study on best practices conducted by the Thinking Ahead Institute, in partnership with the Future Fund. With insights from 26 major funds managing over $6 trillion, the study explores emerging trends, challenges, and best practices in asset ownership. Join us for expert insights from Kristin Magnusson Bernard, Chief Executive Officer of AP1 and study participant, and Roger Urwin, Co-founder of the Thinking Ahead Institute and chief architect of the study. Tune in to gain valuable perspectives from industry leaders on navigating the future of investments in an increasingly complex world. And keep an ear out for part 2 of this episode, out in October. Resources mentioned: Summary report: Global Asset Owner Peer Study Report Virtual event series: Systems Curriculum

On today's episode of The Rush, we welcome fellow Raider, Nate Hobbs! Together the guys talk about what it's like to play with Maxx, playing for Antonio Pierce, Raiders top 5 hoopers, and more! Make sure you subscribe so you never miss an episode of The Rush.Our first merch drop is LIVE, get yours now: https://playmakerbrand.com/collections/the-rushThis episode is brought to you by BetterHelp. Give online therapy a try at betterhelp.com/RUSH and get on your way to being your best self.Save up to 60% off buying last minute for sports, concerts, comedy, theater, etc. Download the Gametime app, create an account, and use code THERUSH for $20 off your first purchase - terms apply. Download now: Gametime.coJoin this channel to get access to perks:https://www.youtube.com/channel/UCedY1vE461NhTXPDfa1r4eA/joinWelcome to "The Rush” where I'll be giving you all an inside look at what really goes on during the season. Stay tuned for weekly breakdowns following Raiders games and a celebration of fellow QB hunters around the leagueChapters:00:00-3:13 Intro3:13-5:20 Nate's community work5:20-7:00 Louisville7:00-9:10 Jack Harlow9:10-10:30 GameTime Ad10:30-15:30 Nates Motivation15:30 - 18:30 Raiders Coaches18:30-19:40 BetterHelp Ad19:40-21:56 Gus Bradley21:56-23:12 Rich Bisaccia23:12-24:20 Playing with Maxx24:20-28:20 Raiders Defense28:20-30:36 Draft Experience30:36-39:40 Nate's Rookie Year39:40-41:00 Maxx' Rookie Year41:00-43:00 Maxx working with rookies43:00-45:00 Believing in yourself45:00-46:10 Maxx working with Jordan and Kobe's trainer46:10-48:48 The Media48:48-51:40 NFL players in the NBA51:40-56:13 Davante Adams & Jakobi Meyers56:13-58:00 Hardest WR's to guard58:00-1:03:00 Raiders starting 5 basketball team1:03:00-1:05:40 Derrick Rose1:05:40-1:09:40 What is Nate working on in the offseason?1:09:40-1:14:28 Offseason Expectations1:14:28-1:17:11 Maxx's offseason approach1:17:11 - 1:21:00 Raider's Defense this year1:21:00 -1:23:00 Playing for AP1:23:00 - 1:24:30 Mount Rush1:24:30 - 1: 26:00 Most Underrated Corners in NFL1:26:00 - 1:28:57 Garrett Wilson1:28:57 - 1:32:30 Keepin' It Creel1:32:30 - 1:33:30 Rush Mail1:33:30 - 1:35:08 Outro#raiders #raidernation #maxx #maxxcrosby #natehobbs Learn more about your ad choices. Visit megaphone.fm/adchoices Hosted on Acast. See acast.com/privacy for more information.

In Episode #4, of IPE's new Leaders in Investment podcast series, IPE editorial director Liam Kennedy interviews Kristin Magnusson Bernard – CEO, AP1. “The main challenge of 2024 will be maintaining the trust in what you do for your beneficiaries so that you are a credible guardian of their wealth.”  The Stockholm-based fund manages around a quarter of the €175bn capital bufferthat backs Sweden's national income pension system. Bernard reflects on AP1 and its investment thinking, as well as on the reasons behind a planned reform of the AP funds. This episode of Leaders in Investment is sponsored by PGIM. About the IPE Podcast series Leaders in Investment In this new podcast series from IPE and IPE Real Assets, members of our editorial team speak to leading figures in the institutional investor community to curate a library of in-depth, focused content.  Conversations with chief investment officers and other asset-owner leaders will range across beliefs, objectives, investment philosophy, strategy and outlook. Engaging with asset owners both in Europe and beyond, this series will provide unique access to the thinking that guides their decisions.See omnystudio.com/listener for privacy information.

Kaum hat man das erste Lehrjahr hinter sich gebracht, man auch schon die Abschlussprüfung Teil 1 vor der Brust. Diese fließt zumindest mit 30 % in die Endnote ein und sollte daher nicht auf die leichte Schulter genommen werden. Aber was genau erwartet einen in der Theorie- und Praxis? Welche Inhalte des 1. und 2. Ausbildungsjahres werden denn nun vorwiegend abgefragt?In dieser Podcastfolge stehen die Elektroniker für Betriebstechnik im Mittelpunkt. Und als gelernter Betriebstechniker teilt Giancarlo the Teacher wertvolle Einblicke in die Inhalte der AP1 und gibt praktische Tipps, wie angehende Elektroniker sich optimal darauf vorbereiten können. Von grundlegenden Schaltungen, bis hin zu fortgeschritteneren Konzepten erklärt er die Schlüsselelemente, die Prüflinge beherrschen sollten. Dabei wird ein besonderer Wert auf praxisnahe Beispiele gelegt, um das Verständnis zu vertiefen.https://www.paypal.com/donate/?hosted_button_id=9UW85PQWLBWZSSupport this podcast at — https://redcircle.com/elektrotechnik-podcast/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

INT: Estamos refletindo numa série de mensagens sobre o Reino de Deus e nos três últimosdomingos vimos que as Escrituras nos apresentam o crescimento do Reino de Deus na história.Vimos as manifestações do Reino de Deus no A.T, o Reino revelado em Jesus Cristo, como oReino que foi aproximado (Mc 1.14-15) e o Reino de Deus na vivência do apóstolo Paulo.Hoje, os nossos olhos se voltarão para a maneira como João tratou desse tema. Em seusescritos, o Reino de Deus aparece 14 vezes, cinco no evangelho de João e nove no Apocalipse.Com a consciência de que João experimentou a alegria de pertencer e de proclamar o Reino deDeus, vamos destacar 4 considerações do apóstolo sobre o Reino de Deus:1)O Reino de Deus só é acessível aos que foram regenerados (Jo 3.3-5)1.1-Ainda que o Reino se manifeste sobre os que não creem e até mesmo rejeitam o governode Deus, só os regenerados o enxergam e entram nele na perspectiva da salvação.1.2-O Senhor Jesus foi enfático ao dizer a Nicodemos que os que não nascerem de novo nãopoderão ver o Reino de Deus, e foi João quem registrou essas palavras.1.3-Essa verdade é importante porque combate a ideia do universalismo e desmonta a falsaideia do tradicionalismo religioso que não valoriza a necessidade de uma conversão genuína.2) O Reino de Deus não é estabelecido na história com as armas deste mundo (Jo 18.36)2.1-Ao afirmar a Pilatos que o seu Reino não era desse mundo, Jesus estava afirmando que oReino de Deus não se estabelece com as armas desse mundo.2.2-Meu Reino não é deste mundo não é sinônimo de alienação, mas de poder superior, demanifestações que não estão submissas a qualquer governo humano e João testemunhou isso(At 4.23-31)3) O Reino de Deus promove comunhão e serviço entre os seus cidadãos (Ap 1.9)3.1-Os irmãos a quem João dirigiu a sua mensagem revelada por Jesus, foram chamados decompanheiros no sofrimento, no Reino e na perseverança.3.2-É essencial que entendamos que o Reino de Deus tem na Igreja, o seu sinal mais visível (Ap1.6; 5.10). Ela não é o Reino, mas ela é do Reino, sinalizando-o na história, porque Deus aconstituiu num Reino de sacerdotes.3.3- Venha o Teu Reino é a oração da Igreja!4)O Reino de Deus se tornará absoluto quando o mal for extirpado da história (Ap 12.10)4.1-O Reino de Deus se consumará na história quando Cristo vier em glória (1 Jo 3.1-3)4.2-E Nessa manifestação gloriosa de Jesus Cristo, o mal será banido da história para sempre(Ap 11.15; 12.10)Aplicações:1.Você já nasceu de novo? (Jo 3.3-5)2.Como cidadão do Reino de Deus, você tem vivido a alegria da comunhão e os compromissosda perseverança, do serviço e do sofrimento pelo Reino? (Ap 1.9)3.Você crê que o Reino de Deus se consumará, todo o mal será banido da história e Deusenxugará dos seus olhos toda lágrima? (Ap 21.1-7)

Our region offers a beautiful bounty of fresh fruits to keep us delighted through each season. This week, Tony and Chef Cindy take us through, season by season, some of their favorite fruits and way ways to incorporate more of them into your routine. Chef Wolf's Clafoutis recipe:oven 400 degreesabout 25 minutesbrush molds with butter and dust with sugar Quantity:3.5 oz Sugar3 TBSP Flour, AP1/2 tsp Baking Powder1/4 tsp Bakins SodaPinch of Salt3 each Whole Eggs3 oz Milk4 oz Melted Butter2 cups Berries or diced peaches or nectarines or bing cherries Method:1. Sift together dry ingredients2. Beat eggs by hand and add to dry ingredients3. Slowly stir in milk and melted butter4. Divide fruit among molds5. Pour batter on top6. Bake until set   This is a rebroadcast.See omnystudio.com/listener for privacy information.

Welcome to Bid Nerds, the show where car enthusiasts John Polnik and Michael Deeb predict and reconcile the results of the latest car auctions. In this episode, we'll be discussing the BaT auction results of a 2000 Honda S2000. This iconic roadster is powered by a 2.0-liter VTEC inline-four engine that produces 240 horsepower and 153 lb-ft of torque, paired with a 6-speed manual transmission. The car is capable of reaching 60 mph in just 5.4 seconds and has a top speed of 150 mph. The Honda S2000 is a rare and highly sought-after vehicle, with only around 65,000 produced worldwide during its production run from 1999 to 2009. This particular model, a 2000 S2000, features the original AP1 body style and is finished in Silverstone Metallic paint. As always, we'll be predicting and reconciling the auction results, discussing the car's history and condition, and offering our expert insights into the market trends and value of this exciting sports car. And don't forget, this episode of Bid Nerds is sponsored by Gaudin Porsche, Gaudin Classic, and The Romi Show Youtube channel. So sit back, relax, and let's dive into the world of car auctions!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.14.532536v1?rss=1 Authors: Rolland, L., Faucherre, A., Mancilla Abaroa, J., Drouard, A., Jopling, C. Abstract: Myocardial damage caused for example by cardiac ischemia leads to ventricular volume overload resulting in increased stretch of the remaining myocardium. In adult mammals, these changes trigger an adaptive cardiomyocyte hypertrophic response which, if the damage is extensive, will ultimately lead to pathological hypertrophy and heart failure. Conversely, in response to extensive myocardial damage, cardiomyocytes in the adult zebrafish heart and neonatal mice proliferate and completely regenerate the damaged myocardium. We therefore hypothesized that in adult zebrafish, changes in mechanical loading due to myocardial damage may act as a trigger to induce cardiac regeneration. Based, on this notion we sought to identify mechanosensors which could be involved in detecting changes in mechanical loading and triggering regeneration. Here we show using a combination of knockout animals, RNAseq and in vitro assays that the mechanosensitive ion channel Trpc6a is required by cardiomyocytes for successful cardiac regeneration in adult zebrafish. Furthermore, using a cyclic cell stretch assay, we have determined that Trpc6a induces the expression of components of the AP1 transcription complex in response to mechanical stretch. Our data highlights how changes in mechanical forces due to myocardial damage can be detected by mechanosensors which in turn can trigger cardiac regeneration. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.14.532574v1?rss=1 Authors: Madan, V., Albacete Albacete, L., Jin, L., Scaturro, P., Watson, J. L., Muschalik, N., Begum, F., Boulanger, J., Bauer, K., Kiebler, M. A., Derivery, E., Bullock, S. L. Abstract: The dynein motor complex mediates polarised trafficking of a wide variety of organelles, intracellular vesicles and macromolecules. These functions are dependent on the dynactin complex, which helps recruit cargoes to dynein's tail region and activates motor movement. How dynein and dynactin orchestrate trafficking of diverse cargoes is unclear. Here, we identify HEATR5B, an interactor of the AP1 clathrin adaptor complex, as a novel player in dynein-dynactin function. HEATR5B is one of several proteins recovered in a biochemical screen for proteins whose association with the human dynein tail complex is augmented by dynactin. We show that HEATR5B binds directly to the dynein tail and dynactin and stimulates motility of AP1-associated endosomal membranes in human cells. We also demonstrate that the HEATR5B homologue in Drosophila is an essential gene that promotes dynein-based transport of AP1-bound membranes to the Golgi apparatus. As HEATR5B lacks the coiled-coil architecture typical of dynein adaptors, our data point to a non-canonical process orchestrating motor function on a specific cargo. We additionally show that HEATR5B promotes association of AP1 with endosomal membranes in a dynein-independent manner. Thus, HEATR5B co ordinates multiple events in AP1-based trafficking. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.27.525517v1?rss=1 Authors: Kinghorn, K., Gill, A., Marvin, A., Li, R., Quigley, K., le Noble, F., Mac Gabhann, F., Bautch, V. L. Abstract: FLT1/VEGFR1 negatively regulates VEGF-A signaling and is required for proper vessel morphogenesis during vascular development and vessel homeostasis. Although a soluble isoform, sFLT1, is often mis-regulated in disease and aging, how sFLT1 is trafficked and secreted from endothelial cells is not well understood. Here we define requirements for constitutive sFLT1 trafficking and secretion in endothelial cells from the Golgi to the plasma membrane, and we show that sFLT1 secretion requires clathrin at or near the Golgi. Perturbations that affect sFLT1 trafficking blunted endothelial cell secretion and promoted intracellular mis-localization in cells and zebrafish embryos. siRNA-mediated depletion of specific trafficking components revealed requirements for RAB27A, VAMP3, and STX3 for post-Golgi vesicle trafficking and sFLT1 secretion, while STX6, ARF1, and AP1 were required at the Golgi. Depletion of STX6 altered vessel sprouting in a 3D angiogenesis model, indicating that endothelial cell sFLT1 secretion is important for proper vessel sprouting. Thus, specific trafficking components provide a secretory path from the Golgi to the plasma membrane for sFLT1 in endothelial cells that utilizes a rare clathrin-dependent intermediate, suggesting novel therapeutic targets. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

- Để nâng cao hiệu quả sản xuất nông nghiệp, nhiều giống cây trồng mới đã được đưa vào thử nghiệm tại đồng đất vùng cao của tỉnh Cao Bằng. Trong số này, gai xanh AP1 là một trong những cây trồng bước đầu mang lại hiệu quả kinh tế cao, mở ra hướng đi mới trong phát triển kinh tế, giảm nghèo cho người dân. Chủ đề : Cây gai xanh AP1, phát triển kinh tế, nông dân Cao Bằng --- Support this podcast: https://anchor.fm/vov1sukien/support

“This is the company that really changed the access the rest of the United States had to get fresh, leafy greens.”   Lori Taylor (5:28-5:35)   Even though Tanimura & Antle wasn't “officially” launched until 1982, the families that make up this incredible fresh produce team have a legacy that stems from 100 years of growing experience. The Tanimura family and Antle family lived 40 miles apart from each other, with the Tanimura family emigrating from Japan and the Antle family migrating to California from Oklahoma during the Dust Bowl in the 1920's. During World War Two, the Antle family agreed to watch over the Tanimura's land while some of the Tanimura family was placed in internment camps and two of the brothers fought in the war.  When the war was over, the two families had an unmatched partnership and bond and decided to join forces; the Tanimuras growing the lettuce and the Antles marketing and selling it under their brand.     What started as a relationship between two families with a love for produce has now grown into a global company with 30,000 acres on the west coast, 7,000 employees annually, and sales across the Nation and internationally. Brian Antle, who got his start on the farm at the ripe age of 14 when he would get paid to move sprinkler pipes (a vital part of irrigation), jokes that “the plan was to get to 100,000 cases of produce a week.”  The company now sells almost 140,000 boxes a day and about 40 million cases a year!   Tanimura & Antle's core products are iceberg lettuce, romaine, red and green leaf, cauliflower, broccoli and celery. They also have organic produce, greenhouse grown produce, and an Artisan line of products that are uniquely branded for their different taste profiles, colors, qualities and crunchability. The Artisan family of specialty produce includes their Artisan Lettuce, Artisan Romaine, Artisan Sweet Gem, Artisan Baby Iceberg, Artisan Sweet Red Onions and Artisan Sweet Broccoli.   “They were the first company that put iceberg lettuce on a rail car on ice and shipped it from California to New York City and it arrived fresh. From there, as they say, the rest is history.” Lori Taylor (5:45-5:56)   The cool thing about Tanimura & Antle is the many ‘firsts' the company has ignited for the produce industry. Their family was the first to pack and wrap a head of lettuce in cellophane. They were also the first to use cardboard boxes and cool produce in vacuum cooling tubes prior to shipping, allowing the entire produce industry to move away from needing to ice everything and use rail cars.  Speaking of innovation, Tanimura & Antle even breeds their own seed genetics! The company can tailor their lettuce, to have a certain color, size or taste. They can also breed plants to become more resistant to certain disease or mildew pressures. Innovations in seed genetics ultimately allows Tanimura & Antle to harvest more product for consumption and decrease food waste at the field level. This is all done through natural plant breeding, none of these seeds are genetically modified organisms (GMOs).  Tanimura & Antle truly strives to find sustainability in every corner of their operations!     Another innovative practice of the company is the use of automated technology. Tanimura & Antle has a group of diversified businesses, one of those being Stout, a company focused on “smart farm equipment”. With the cost and shortages of skilled agricultural labor, farmers are being challenged with doing more with less every day. Tanimura & Antle is investing in machines that can help supplement these labor shortages, such as machines that eliminate weeds in the field using artificial intelligence and computer vision systems. Machines like this will allow farmers to [AP1] utilize the employees in areas of agricultural production that cannot be automated, such as harvesting or operating these new machines.  While this type of innovation can sometimes be viewed as eliminating jobs, they're not.  Innovations like this allow farmers to supplement the shortages within their work force in order to continue to feed the world.    “The ground is the most valuable asset we have next to our employees. Without either one, there is no sustainability.” Brian Antle (29:16-29:23)   One key to Tanimura & Antle's success is how much they value the ground they grow on. They're constantly rotating their crops and focus on keeping the ground healthy. Without healthy soil, they know they cannot grow a healthy crop. Tanimura & Antle views their employees as their #1 asset.  They ensure their employees are taken care of by providing things like a low cost employee housing complex, access to full health benefits, a matched 401k and one of the their proudest innovations, an Employee Stock Ownership Plan (ESOP).  They were one of the first major grower shippers to adopt an ESOP in the United States!  In 2017, the Tanimura and Antle families made the decision to make their employees official business partners and sold a portion of the company to the employees, creating the ESOP.  The ESOP allows employees to earn ownership stocks of the company through years of service and loyalty to the company.   When it comes to enjoying their produce, make sure to try one of their Artisan or Greenhouse Grown vegetables. You can find Tanimura & Antle in most major grocery retailers across North America, and if not, be sure to ask your local produce manager to put Tanimura & Antle's branded items on your grocery store shelf!  How to get involved Join The Produce Moms Group on Facebook and continue the discussion every week!  Reach out to us - we'd love to hear more about where you are in life and business! Find out more here.    If you liked this episode, be sure to subscribe and leave a quick review on iTunes. It would mean the world to hear your feedback and we'd love for you to help us spread the word!

As many people throughout the country continued to stay home in an effort to slow the spread of COVID-19,one father-daughter duo,Deepak Bajrachary,a prolific singer,lyricist and musician and Cherisa Bajrachary, an aspring singer were making our hearts melt with their heartwarming singing session in helping spread joy and positivity through Online show “The Musical Medicine show” during lockdown.At the time, they didn’t think that their performance would reach beyond their close friends and family, But to their surprise, the numbers kept rising and audience showered so much love and support.The show succeeded in giving out the message that no matter how the gruelling lockdown and all the anxiety makes reconnecting with our loved ones is more important than ever. In order to give the show a continuity & to reach wider audience, both have now been hosting it as a weekly musical show officially in AP1. This show aims to present the musical viewpoints between the people from different generation while also promoting a number of young musical talents hailing from different parts of the country. This show also provide a great insight on the beautiful relationship of father and daughter duo, their strong bonding and yet as an indivisual, how each percieve/compare the old versus new music to their own musical idealogies. Despite the different tastes in music, both Duo certainly agrees at one point that music is a great healer and all of us respond to it.   live at https://www.facebook.com/thedeepeshshow https://www.youtube.com/thedeepeshshowhttp://www.twitter.com/thedeepeshshow   Podcastshttps://www.thedeepeshshow.com   #DeepakBajracharya #CherishaBajracharya #TMMS #TheDeepeshShow #NepaliPodcast  #aeglobal #giftmandu #wowpal #liveinterview

In this episode, we’re going to cover a small topic of the CWAP certification. We’re taking a look at the frame exchanges that occur during 802.11r or Fast BSS Transition. In our scenario we’ll use my iPhone which associates to AP1 and roams to AP2. Without 802.11r, the roam will take additional time to complete. […] The post CTS 251 – Fast BSS Transition Frame Exchanges (CWAP) appeared first on Clear To Send.

In the third episode of Allocator's Corner, I had the opportunity to sit down with Helen Idenstedt who is portfolio manager idiosyncratic alternative investments at the first Swedish national pension fund - AP1. The role of the portfolio that Helen runs is to serve as a diversified source of alpha within the broader AP1 mandate – a mandate that currently has around 350 billion SEK in assets under management. During the session, we discussed how to manage so-called idiosyncratic risk using alternative investment strategies, the process behind her manager selection, what the portfolio looks like today and how ESG has received increased attention in the alternatives space as of late. We also had the chance to discuss a new mandate linked to private debt strategies that Helen has just started allocating assets to.

Wie schon der Episodentitel vermuten lässt, kommt es in dieser BVBeben-Folge so, wie es jeder der selber das Duell gegen Barca gesehen hat erwarten sollte. Man ist verzweifelt, überfordert, bedient. Die Kurzanalyse zum Duell gegen die Katalanen gibt es natürlich trotzdem, einen kleinen Ausflug in Richtung Sancho ( Der eigentlich am Podcast teilnehmen wollte aber einfach nicht erschien) und die deprimierendste Spielvorschau dieser Podcastreihe. Lasst es uns hinter uns bringen und dann reden wir nächste Wcche nochmal, JA? Liebe Grüße, Sad Guy Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten.

Wie schon der Episodentitel vermuten lässt, kommt es in dieser BVBeben-Folge so, wie es jeder der selber das Duell gegen Barca gesehen hat erwarten sollte. Man ist verzweifelt, überfordert, bedient. Die Kurzanalyse zum Duell gegen die Katalanen gibt es natürlich trotzdem, einen kleinen Ausflug in Richtung Sancho ( Der eigentlich am Podcast teilnehmen wollte aber einfach nicht erschien) und die deprimierendste Spielvorschau dieser Podcastreihe. Lasst es uns hinter uns bringen und dann reden wir nächste Wcche nochmal, JA? Liebe Grüße, Sad Guy...

Wie schon der Episodentitel vermuten lässt, kommt es in dieser BVBeben-Folge so, wie es jeder der selber das Duell gegen Barca gesehen hat erwarten sollte. Man ist verzweifelt, überfordert, bedient. Die Kurzanalyse zum Duell gegen die Katalanen gibt es natürlich trotzdem, einen kleinen Ausflug in Richtung Sancho ( Der eigentlich am Podcast teilnehmen wollte aber einfach nicht erschien) und die deprimierendste Spielvorschau dieser Podcastreihe. Lasst es uns hinter uns bringen und dann reden wir nächste Wcche nochmal, JA? Liebe Grüße, Sad Guy

Hallo Freunde des gepflegten BVB-Talks. Natürlich gibt es im Moment dankbarere Aufgaben als sich mit dem BVB zu beschäftigen und vor allem mit dem Spiel gegen Paderborn am vergangenen Spieltag. Doch es hilft ja nichts und nach leichtem Verzagen konnte auch Julius Eid mit gebrochenem Herzen zur Aufnahme einer neuen Folge überredet werden. Denn das ist nun mal unser Job hier. Es gibt also die ausführliche Analyse der 3:3-Niederlage vom Freitag. Inklusive flammender Appelle. Aber das ist natürlich nicht alles. Denn heute Abend steht trotz aller Niedergeschlagenheit ein wahrlich großes Duell für unsere Borussia auf dem Zettel. Im Camp Nou gegen den FC Barcelona. Mit einem Punktgewinn (und der ist leider nicht allzu wahrscheinlich) könnte man einen großen Schritt Richtung KO-Phase der Königsklasse machen. Was wir bei den Katalanen erwarten? Und wie Christoph Albers auf sehr gute Witze reagiert? Hört rein und dann könnt ihr es euren Freunden erzählen. Liebe Grüße, El Corazon Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten.

Hallo Freunde des gepflegten BVB-Talks. Natürlich gibt es im Moment dankbarere Aufgaben als sich mit dem BVB zu beschäftigen und vor allem mit dem Spiel gegen Paderborn am vergangenen Spieltag. Doch es hilft ja nichts und nach leichtem Verzagen konnte auch Julius Eid mit gebrochenem Herzen zur Aufnahme einer neuen Folge überredet werden. Denn das ist nun mal unser Job hier. Es gibt also die ausführliche Analyse der 3:3-Niederlage vom Freitag. Inklusive flammender Appelle. Aber das ist natürlich nicht alles. Denn heute Abend steht trotz aller Niedergeschlagenheit ein wahrlich großes Duell für unsere Borussia auf dem Zettel. Im Camp Nou gegen den FC Barcelona. Mit einem Punktgewinn (und der ist leider nicht allzu wahrscheinlich) könnte man einen großen Schritt Richtung KO-Phase der Königsklasse machen. Was wir bei den Katalanen erwarten? Und wie Christoph Albers auf sehr gute Witze reagiert? Hört rein und dann könnt ihr es euren Freunden erzählen. Liebe Grüße, El Corazon

Hallo Freunde des gepflegten BVB-Talks. Natürlich gibt es im Moment dankbarere Aufgaben als sich mit dem BVB zu beschäftigen und vor allem mit dem Spiel gegen Paderborn am vergangenen Spieltag. Doch es hilft ja nichts und nach leichtem Verzagen konnte auch Julius Eid mit gebrochenem Herzen zur Aufnahme einer neuen Folge überredet werden. Denn das ist nun mal unser Job hier. Es gibt also die ausführliche Analyse der 3:3-Niederlage vom Freitag. Inklusive flammender Appelle. Aber das ist natürlich nicht alles. Denn heute Abend steht trotz aller Niedergeschlagenheit ein wahrlich großes Duell für unsere Borussia auf dem Zettel. Im Camp Nou gegen den FC Barcelona. Mit einem Punktgewinn (und der ist leider nicht allzu wahrscheinlich) könnte man einen großen Schritt Richtung KO-Phase der Königsklasse machen. Was wir bei den Katalanen erwarten? Und wie Christoph Albers auf sehr gute Witze reagiert? Hört rein und dann könnt ihr es euren Freunden erzählen. Liebe Grüße, El Corazon...

Under Pressure (Düm Düm Düm dö Dö Düm Düm). Das ist eigentlich ausreichend um die Situation für Lucien Favre beim BVB zu beschreiben. Aber da unsere beiden Moderatoren Julius Eid und Christoph Albers nicht viel mehr gelernt haben als zu reden, führen sie die Gesamtsituation natürlich auch in dieser Folge BVBeben deutlich wortgewaltiger aus. Gemeinsam wird auf das anstehende Bundesligaspiel gegen Paderborn geschaut und erklärt, warum das Tabellenschlusslicht ein taktisch dankbarer Gegner sein könnte. Und eben warum nicht nur ein Sieg für die Borussia und ihren Chefcoach zählt sondern auch die Art und Weise. Natürlich werden dann auch noch alle Hörerfragen beantwortet. All-In-One-Daycare presented by BVBeben. Genießt die Show. Liebe Grüße, der Nachbar von dem Einen.

Under Pressure (Düm Düm Düm dö Dö Düm Düm). Das ist eigentlich ausreichend um die Situation für Lucien Favre beim BVB zu beschreiben. Aber da unsere beiden Moderatoren Julius Eid und Christoph Albers nicht viel mehr gelernt haben als zu reden, führen sie die Gesamtsituation natürlich auch in dieser Folge BVBeben deutlich wortgewaltiger aus. Gemeinsam wird auf das anstehende Bundesligaspiel gegen Paderborn geschaut und erklärt, warum das Tabellenschlusslicht ein taktisch dankbarer Gegner sein könnte. Und eben warum nicht nur ein Sieg für die Borussia und ihren Chefcoach zählt sondern auch die Art und Weise. Natürlich werden dann auch noch alle Hörerfragen beantwortet. All-In-One-Daycare presented by BVBeben. Genießt die Show. Liebe Grüße, der Nachbar von dem Einen. Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten.

Under Pressure (Düm Düm Düm dö Dö Düm Düm). Das ist eigentlich ausreichend um die Situation für Lucien Favre beim BVB zu beschreiben. Aber da unsere beiden Moderatoren Julius Eid und Christoph Albers nicht viel mehr gelernt haben als zu reden, führen sie die Gesamtsituation natürlich auch in dieser Folge BVBeben deutlich wortgewaltiger aus. Gemeinsam wird auf das anstehende Bundesligaspiel gegen Paderborn geschaut und erklärt, warum das Tabellenschlusslicht ein taktisch dankbarer Gegner sein könnte. Und eben warum nicht nur ein Sieg für die Borussia und ihren Chefcoach zählt sondern auch die Art und Weise. Natürlich werden dann auch noch alle Hörerfragen beantwortet. All-In-One-Daycare presented by BVBeben. Genießt die Show. Liebe Grüße, der Nachbar von dem Einen....

Es geht uns schlecht. So richtig schlecht. Das Herz der beiden Moderatoren von BVBeben ist mal wieder ein kleines bisschen mehr zerbrochen. Denn nach vielversprechenden Auftritten in den letzten Wochen und unangenehm gutgelaunten Podcast-Folgen, hat der BVB beschlossen, die Stimmung mal wieder richtig runterzuziehen. Im Duell gegen den Konkurrenten aus Münchern zeigte man eine Leistung, die es eigentlich unmöglich macht von Konkurrenz zu sprechen. Sprechen müssen wir trotzdem wieder und tun das auch ausführlich in der neuesten Episode des Erfolgspodcasts BVBeben, Träger der Teilnehmerurkunde der Bundesjugendspiele 2002. Liebe Grüße, die Euphoriebremse. Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten.

Es geht uns schlecht. So richtig schlecht. Das Herz der beiden Moderatoren von BVBeben ist mal wieder ein kleines bisschen mehr zerbrochen. Denn nach vielversprechenden Auftritten in den letzten Wochen und unangenehm gutgelaunten Podcast-Folgen, hat der BVB beschlossen, die Stimmung mal wieder richtig runterzuziehen. Im Duell gegen den Konkurrenten aus Münchern zeigte man eine Leistung, die es eigentlich unmöglich macht von Konkurrenz zu sprechen. Sprechen müssen wir trotzdem wieder und tun das auch ausführlich in der neuesten Episode des Erfolgspodcasts BVBeben, Träger der Teilnehmerurkunde der Bundesjugendspiele 2002. Liebe Grüße, die Euphoriebremse.

Es geht uns schlecht. So richtig schlecht. Das Herz der beiden Moderatoren von BVBeben ist mal wieder ein kleines bisschen mehr zerbrochen. Denn nach vielversprechenden Auftritten in den letzten Wochen und unangenehm gutgelaunten Podcast-Folgen, hat der BVB beschlossen, die Stimmung mal wieder richtig runterzuziehen. Im Duell gegen den Konkurrenten aus Münchern zeigte man eine Leistung, die es eigentlich unmöglich macht von Konkurrenz zu sprechen. Sprechen müssen wir trotzdem wieder und tun das auch ausführlich in der neuesten Episode des Erfolgspodcasts BVBeben, Träger der Teilnehmerurkunde der Bundesjugendspiele 2002. Liebe Grüße, die Euphoriebremse....

Was haben wir gelitten in den letzten Wochen, nach einem besonderen Fußball-Erlebnis geschmachtet. Und siehe da, wir wurden erhört. Lucien Favre und der BVB zauberten in der zweiten Halbzeit gegen Inter Mailand eine solch überzeugende Leistung aus dem Hut, oder Chapeau, wie der Trainer sagen würde, dass Julius Eid sogar eine ganze Kneipe hinter sich wusste. Wer wissen will wie das passieren konnte? Der sollte dringend reinhören. Fast schon unangenehm gut gelaunt wird nämlich auf das Duell gegen die Italiener zurückgeblickt. Und da man nicht nur in der Vergangenheit leben soll, wird auch der Blick in die Zukunft gewagt. Gemeinsam mit Gast Manuel Behlert blicken wir auf das anstehende Duell gegen den FC Bayern voraus. Man kann echt nix mit dieser Folge falsch machen. Liebe Grüße, Der Türsteher Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten.

Was haben wir gelitten in den letzten Wochen, nach einem besonderen Fußball-Erlebnis geschmachtet. Und siehe da, wir wurden erhört. Lucien Favre und der BVB zauberten in der zweiten Halbzeit gegen Inter Mailand eine solch überzeugende Leistung aus dem Hut, oder Chapeau, wie der Trainer sagen würde, dass Julius Eid sogar eine ganze Kneipe hinter sich wusste. Wer wissen will wie das passieren konnte? Der sollte dringend reinhören. Fast schon unangenehm gut gelaunt wird nämlich auf das Duell gegen die Italiener zurückgeblickt. Und da man nicht nur in der Vergangenheit leben soll, wird auch der Blick in die Zukunft gewagt. Gemeinsam mit Gast Manuel Behlert blicken wir auf das anstehende Duell gegen den FC Bayern voraus. Man kann echt nix mit dieser Folge falsch machen. Liebe Grüße, Der Türsteher

Was haben wir gelitten in den letzten Wochen, nach einem besonderen Fußball-Erlebnis geschmachtet. Und siehe da, wir wurden erhört. Lucien Favre und der BVB zauberten in der zweiten Halbzeit gegen Inter Mailand eine solch überzeugende Leistung aus dem Hut, oder Chapeau, wie der Trainer sagen würde, dass Julius Eid sogar eine ganze Kneipe hinter sich wusste. Wer wissen will wie das passieren konnte? Der sollte dringend reinhören. Fast schon unangenehm gut gelaunt wird nämlich auf das Duell gegen die Italiener zurückgeblickt. Und da man nicht nur in der Vergangenheit leben soll, wird auch der Blick in die Zukunft gewagt. Gemeinsam mit Gast Manuel Behlert blicken wir auf das anstehende Duell gegen den FC Bayern voraus. Man kann echt nix mit dieser Folge falsch machen. Liebe Grüße, Der Türsteher...

I avsnitt 77 av vår podcast Björnfällan välkomnar vi Martin Källström från Lynx Asset Management. Det blir ett spännande samtal om hans tid som ansvarig för alternativa investeringar på AP1, synen på risk, överoptimering vid backtest, maskininlärning, om traditionella trendföljande strategier fortfarande fungerar, volmageddon i februari 2018, trendföljande som diversifiering, grunden till varför trendföljande fungerar, positionshantering, riskkontroll, Lynx nya fond och mycket mer. Björnfällan är en ekonomi- och finanspodcast presenterad av CMC Markets riktad mot intressenter av aktiv handel. Programmet har ett öppet format och kommer varannan vecka att ta upp ämnen som berör trading, bolag och globala trender inom finansmarknaden. Programledare är Kristofer Berggren och Nils Brobacke. Följ oss på Twitter på www.twitter.com/cmcmarketsswe och ställ dina frågor till oss på hashtagen #björnfällan — CMC Markets är noterade på Londonbörsen och är en av världens största CFD-aktörer. Vi erbjuder handel i aktier, index, råvaror och valuta i fler än 10 000 produkter världen över. Vår handelsplattform har vunnit ett flertal priser. Testa ett demokonto på www.cmcmarkets.se Vår podcast ska endast ses som generell information och syftar inte till att ge handels- eller investeringsrådgivning eller personliga rekommendationer. Historisk avkastning är inte någon garanti för framtida avkastning. CMC ska inte hållas ansvarig för någon förlust som drabbar dig, direkt eller indirekt, från någon investering baserad på information i denna video. Kom ihåg att handel med CFDs innebär en hög risk och det kan vara så att det inte är en lämplig produkt för alla investerare. Förluster kan överstiga dina insättningar.

Show #476   Good morning, good afternoon and good evening wherever you are in the world, welcome to EV News Daily for Sunday 19th May 2019. It’s Martyn Lee here and welcome to another Saturday Special interview.   Thank you to MYEV.com for helping make this show, they’ve built the first marketplace specifically for Electric Vehicles. It’s a totally free marketplace that simplifies the buying and selling process, and help you learn about EVs along the way too.   Hello to new Patreon supporters - firstly on Patreon it's just NATHAN. Plus thanks to new Producer PHILLIP STONE and Producer DR FRANK KEARNEY.   VOLKSWAGEN BRINGING 48V MHEV TO EIGHT-GENERATION GOLF The eighth-generation of the bestselling Volkswagen Golf bestseller will feature a 48V mild hybrid electric drive system. In 2018, Volkswagen announced at the Vienna The Group is now delivering on its promise and bringing the technology into series production this year with the eighth generation Golf, one of the best-selling vehicles in the world. Initially, the 48V hybrid drive will be available with the EA211 evo family, 1.0 and 1.5l displacement and dual-clutch gearbox (DSG)." reports Green Car Congress: "Compared to current Plug-in Hybrids (PHEV), for example in the Golf GTE and Passat GTE, the MHEV drive equipped with 48V technology offers a reduced range of functions, but is significantly more cost-effective. While the Plug-in Hybrid (PHEV) charges the battery via the grid with a plug, the MHEV does not have a battery that can be recharged via a plug, but is equipped with a 48V belt starter generator."   https://www.greencarcongress.com/2019/05/201900518-golf48.html   TESLA INSURANCE INFO LEAKED InsideEVs says: "Our Twitter friends @TheTeslaShow have uncovered the very first bit of real information on Tesla's planned car insurance program. This leaked bit of code has now vanished, but thanks to the quick work of @TheTeslaShow, we've got the info right here for you. Tesla (well, mainly Elon Musk) seems to think this insurance offering will be a huge addition for the automaker, though others disagree, as the insurance business is indeed a tricky one to conquer. Regardless, it seems Tesla is pushing forward with this and now we have some concrete proof."   "Introducing Tesla Insurance. Select Tesla Insurance for low rates and one seamless experience. Match your existing coverage or select a new plan with an instant quote."   https://insideevs.com/news/350174/tesla-insurance-info-leak/   CHEVY BOLT EUV ELECTRIC CROSSOVER CAUGHT IN THE WILD "[GM has] said it will build another crossover alongside the Bolt, which is rumored to be called the Bolt EUV (as a trademark dug up by GM Authority could suggest), and is almost certainly what you see in the photos caught by our spy photographer, above." according to Autoblog: "This definitely looks more like a legitimate crossover than the Bolt (which Chevy also, questionably, refers to as a crossover), but beyond its more upright stance, it's hard to tell what this thing actually looks like under that thick cladding and camouflage. We expect it to be larger than the current Bolt, but it's hard to tell by how much until some of the camo comes off. We can see that there's no exhaust, and the video below confirms it runs silently as expected for an electric car. We don't have official word yet, but based on intel and GM's general timeline, we could likely see a production version of the vehicle you see in these spy photos come late next year."   https://www.autoblog.com/2019/05/17/chevy-bolt-euv-electric-crossover-spy-photos/?guccounter=1   BOLT MOBILITY UNVEILS $9,999 ELECTRIC CAR "Usain Bolt, the world’s fastest human, is backing an electric car startup based in Florida called Bolt Mobility. This past week, the company unveiled its first car, the B-Nano, which it says it has been working on in secret for the past two years." reports Clean Technica: "According to AutoBlog, the B-Nano — which resembles the Renault Twizy in size and simplicity — is intended to be used much like the two wheeled vehicles used in bike sharing schemes. Short trips of between 2 and 15 miles are its design envelope. No maximum range or top speed is specified by the company. But the battery — whatever size it is — is engineered to be easily swapped out for fresh battery quickly and easily. Just who would be doing the swapping and where and for how much are questions with no answers at present. What is known is that the base model of the B-Nano will sell for a mere $9,999. Reservations are being accepted now for just $999."   https://cleantechnica.com/2019/05/19/bolt-mobility-unveils-9999-electric-car-designed-for-car-sharing-in-cities/   QUESTION OF THE WEEK   David Allen If I must make a decision, then it is imperative hardware is right at the outset. Once the car is in the field, it gets VERY expensive to fix, replace, or upgrade hardware. Software, thanks to OTA updates, can be fixed, and features can be added, but only to the limits of the hardware.   Rich Fowler Hardware! Specifically, seats! Software can't fix a terrible seat. My analogy is  that if you play cards, the hardware is the deck, and the software is the rule set. If the deck is missing half the cards, you can't play a lot of games you want to play with it, and you have to invent some other game with a different set of rules. That new game may or may not be more fun, but it's not the game you were looking for when you bought the deck in the first place.   John Fruhwirth Since you are forcing us to choose between hardware and software as being more important in our EVs, I'm coming down on the side of hardware. Why? because hardware is the necessary basis/foundation for software. Without hardware to run on, software is useless. However, the reverse is not true. Hardware is definitely useful without software as we can compensate for the lack of software with our wet/brain ware. So, while software is nice, hardware is a must. However, the combination of hardware and software is where it's at and gives us the biggest bang for our transportation bucks.   Ron KeRENski I think the right answer, for where we are in the EV market evolution, is actually hardware.  Assuming a starting point with comparable software capabilities, the right hardware in a car rolling off of the line today means that software improvements over the next 5-10 years can reach backwards to owners.  Nothing builds brand loyalty like not being left behind and improving the resale value of my trade-in due to a high demand, used market.   Will Adams  since you aren’t allowing the correct answer it has to be Software that is more important. Great software can make bad hardware work, but really bad software can make even the best hardware unusable   Howard Smith Hardware is the most important part to get right on an EV. Hardware reliability provides value because the car will last longer. EV owners have to pay more upfront for their cars; they need to be durable over the long run. Software is easily updated; hardware is not.   David Nye This is a very easy one to answer, no fence sitting necessary. Hardware is king, it must be right from day one.  Software finessing and “polishing” can follow later with OTA updates. Tesla is of course the classic example- early release software in Teslas has at times had it’s issues, and of course critics, but it just keeps getting better and better. The Tesla you drive today will only be better in a year’s time. Imagine if you had to keep visiting the service centre for hardware fixes!   Rob Crawford If your EV has FSD, then the hardware is more important. Simpley because it's the hardware that allows the car to drive in FSD mode. Without the hardware FSD isn't possible. And the hardware must be strong, rugged dependable to function perfectly, immatating what a driver can do only better. Now... I can answer the same question about the importance of the software. Software also plays an important part when it comes to FSD, without over the air updates, then the FSD will lag, and won't run correctly, as designed. So my answer is both Hardware and Software are important for the safest in functionality of an EV, especially pertaining to FSD. Software is important to the functionality of EVs in general.  An ICE car couldn't even function as a self driving car.   Tony Goodwin After a lot of thought, on balance hardware - in particular the fitment of sensors and processing power allowing for additional functionality - is much more important than software. Hardware changes post-delivery will likely be both difficult and expensive to fit and always require a dealer visit, whereas software can add capabilities to existing hardware as techniques are refined and "AI" knowledge iterates. It is also possible to do this OTA as well as being carried out at dealerships.   Victor Wood Hardware is the most important to get correct. Software can always be updated relatively easily whereas hardware is not something that can be easily and cheaply swapped out.  The cost of looking out say an autopilot hardware swap out must be sky high compared to the cost of pushing software over the air.  For cars like mine where there is no OTA updates it’s still cheap to do a software update as in effect it’s “only” the time to put the software onto an SD card and to put that in the car that causes costs. The last 2 updates for my Ioniq I did myself after getting the software on an SD card from the dealer. It took 15 minutes.   Andrew Beshera Hardware is more important over software because software is cheaper & easier to update.   Andrew Jacobs Software is easily more important because you can have the best hardware in the world and bad software will render it useless. If you have great software and poor hardware, the software is going to improve the hardware limitations. Just look at the YouTube videos where people cover cameras to see how well autopilot works. Autopilot mainly uses the front forward stereo cameras. Even with the others blocked it can still work. Software is king.   Bill Pollock HARDWARE is the most important thing to get right off the start. Hardware is expensive to upgrade, and often can not be done.  I do however think that hardware should be designed to be as swapable as possible.  For example, as battery tech improves, we should be able to upgrade with minimal intrusion. BTW-The Tesla Model 3 is not an easy battery to swap.  The tech has to basically dismantle the interior of the car to get at fasteners. The S and X batteries were designed for easy replacement.  I hope they Y has corrected this Model 3 shortfall.   Michael McClure This is a no brainer. Hardware is static; software is not.I drive a 2015 Tesla Model S with AP1 that I picked up used last year. That’s old hardware, but I keep getting OTA updates all the time that make it feel ‘new’.   Aaron Patel Hardware. You can't change the number of cells in your battery once it's sitting in your driveway. Autopilot software can be okay today but then gets incrementally better month after month until it's great. I just reached 1 year in my Model 3 and the day after I picked it up I got a software update that added automatic wipers. Cabin overheat protection, Nav on Auto, TeslaCam, Sentry Mode, Atari games, dog mode...... 28,000 miles later, the car keeps getting better!     COMMUNITY And thanks to MYEV.com they’ve set us another Question Of The Week. Keep your comments coming in on email and YouTube…   Does the location of production influence your buying decions? And why?   I want to say a heartfelt thank you to the 214 patrons of this podcast whose generosity means I get to keep making this show, which aims to entertain and inform thousands of listeners every day about a brighter future. By no means do you have to check out Patreon but if it’s something you’ve been thinking about, by all means look at patreon.com/evnewsdaily     PHIL ROBERTS / ELECTRIC FUTURE (PREMIUM PARTNER) BRAD CROSBY (PREMIUM PARTNER)   DAVID ALLEN (PARTNER) OEM AUDIO OF NEW ZEALAND AND EVPOWER.CO.NZ (PARTNER) PAUL O’CONNER (PARTNER) ALAN ROBSON (EXECUTIVE PRODUCER) ALEX BANAHENE (EXECUTIVE PRODUCER) ALEXANDER FRANK @ https://www.youtube.com/c/alexsuniverse42 ANDERS HOVE (EXECUTIVE PRODUCER) ARILD GEIR SKAALSVEEN (EXECUTIVE PRODUCER) ASHLEY HILL (EXECUTIVE PRODUCER) BÅRD FJUKSTAD (EXECUTIVE PRODUCER) BARRY PENISTON (EXECUTIVE PRODUCER) BOB MUIR / GINGERCOMPUTERS.COM IN DUNDEE (EXECUTIVE PRODUCER) BORISLAV BORISOV (EXECUTIVE PRODUCER) BRENT KINGSFORD (EXECUTIVE PRODUCER) BRIAN THOMPSON (EXECUTIVE PRODUCER) BRIAN WEATHERALL (EXECUTIVE PRODUCER) CESAR TRUJILLO (EXECUTIVE PRODUCER) CHRIS BENSON (EXECUTIVE PRODUCER) CHRIS HOPKINS (EXECUTIVE PRODUCER) CRAIG COLES (EXECUTIVE PRODUCER) CRAIG ROGERS (EXECUTIVE PRODUCER) DAMIEN DAVIS (EXECUTIVE PRODUCER) DARREN BYRD (EXECUTIVE PRODUCER) DARREN SANT FROM YORKSHIRE EV CLUB (EXECUTIVE PRODUCER) DAVE DEWSON (EXECUTIVE PRODUCER) DAVID BARKMAN (EXECUTIVE PRODUCER) DAVID FINCH (EXECUTIVE PRODUCER) DAVID PARTINGTON (EXECUTIVE PRODUCER) DAVID PRESCOTT (EXECUTIVE PRODUCER) DIRK RUTSATZ (EXECUTIVE PRODUCER) DON MCALLISTER / SCREENCASTSONLINE.COM (EXECUTIVE PRODUCER) ENRICO STEPHAN-SCHILOW (EXECUTIVE PRODUCER) FREDRIK ROVIK (EXECUTIVE PRODUCER) FREEJOULE AKA JAMES (EXECUTIVE PRODUCER) GEORGE CLARGO (EXECUTIVE PRODUCER) JACK OAKLEY (EXECUTIVE PRODUCER) JAMES STORR (EXECUTIVE PRODUCER) JASON FAN (EXECUTIVE PRODUCER) JEFF ERBES (EXECUTIVE PRODUCER) JERRY ALLISON (EXECUTIVE PRODUCER) JILL SMITH (EXECUTIVE PRODUCER) JOHN BAILEY (EXECUTIVE PRODUCER) JON AKA BEARDY MCBEARDFACE FROM KENT EVS (EXECUTIVE PRODUCER) JON KNODEL (EXECUTIVE PRODUCER) JON TIMMIS (EXECUTIVE PRODUCER) JUAN GONZALEZ (EXECUTIVE PRODUCER) KEN MORRIS (EXECUTIVE PRODUCER) KEVIN MEYERSON (EXECUTIVE PRODUCER) LARS DAHLAGER (EXECUTIVE PRODUCER) LAURENCE D ALLEN (EXECUTIVE PRODUCER) LEO (EXECUTIVE PRODUCER) LESZEK GRZYL (EXECUTIVE PRODUCER) LOUIS HOPKIN (EXECUTIVE PRODUCER) LUKE CULLEY (EXECUTIVE PRODUCER) MARCEL LOHMANN (EXECUTIVE PRODUCER) MARCEL WARD (EXECUTIVE PRODUCER) MARLIN SCHELL (EXECUTIVE PRODUCER) MARTIN CROFT (EXECUTIVE PRODUCER) MATT PISCIONE (EXECUTIVE PRODUCER) MATTHEW ELLIS (EXECUTIVE PRODUCER) MATTHEW GROOBY (EXECUTIVE PRODUCER) MAZ SHAR (EXECUTIVE PRODUCER) MIA OPPELSTRUP (EXECUTIVE PRODUCER) MICHAEL PASTRONE (EXECUTIVE PRODUCER) MIKE ROGERS (EXECUTIVE PRODUCER) MIKE WINTER (EXECUTIVE PRODUCER) NATHAN GORE-BROWN (EXECUTIVE PRODUCER) NEIL E ROBERTS FROM SUSSEX EVS (EXECUTIVE PRODUCER) OHAD ASTON (EXECUTIVE PRODUCER) PAUL SEAGER-SMITH (EXECUTIVE PRODUCER) PAUL STEPHENSON (EXECUTIVE PRODUCER) PETE GLASS (EXECUTIVE PRODUCER)  PHIL MOUCHET (EXECUTIVE PRODUCER) PHILIPPE CALVE (EXECUTIVE PRODUCER) RAJ BADWAL (EXECUTIVE PRODUCER) RAJEEV NARAYAN (EXECUTIVE PRODUCER) RALPH JENSON (EXECUTIVE PRODUCER) RENÉ SCHNEIDER (EXECUTIVE PRODUCER) ROB COOLING / HTTP://WWW.APPLEDRIVING.CO.UK/ (EXECUTIVE PRODUCER) RUPERT MITCHELL (EXECUTIVE PRODUCER) SARAH MCCANN (EXECUTIVE PRODUCER) SARI KANGASOJA (EXECUTIVE PRODUCER) SEIKI PAYNE (EXECUTIVE PRODUCER) STEVE JOHN (EXECUTIVE PRODUCER) STUART HANNAH (EXECUTIVE PRODUCER) THE LIMOUSINE LINE SYDNEY (EXECUTIVE PRODUCER) TIM GUTTERIDGE (EXECUTIVE PRODUCER) WALTER MACVANE (EXECUTIVE PRODUCER) ZACK HURST (EXECUTIVE PRODUCER)   You can listen to all 475 previous episodes of this this for free, where you get your podcasts from, plus the blog https://www.evnewsdaily.com/ – remember to subscribe, which means you don’t have to think about downloading the show each day, plus you get it first and free and automatically. It would mean a lot if you could take 2mins to leave a quick review on whichever platform you download the podcast. And if you have an Amazon Echo, download our Alexa Skill, search for EV News Daily and add it as a flash briefing. Come and say hi on Facebook, LinkedIn or Twitter just search EV News Daily, have a wonderful day, I’ll catch you tomorrow and remember…there’s no such thing as a self-charging hybrid.   CONNECT WITH ME! EVne.ws/itunes EVne.ws/tunein EVne.ws/googleplay EVne.ws/stitcher EVne.ws/youtube EVne.ws/iheart EVne.ws/blog EVne.ws/patreon   Check out MYEV.com for more details: https://www.myev.com

Ap1

While previewing the new stuff at this year's PGA Show coming up this week, Jeff extolls the virtues of the new Titleist AP irons. Whether the AP1, AP2, or AP3, one will be perfect for you, no matter how well you do or do not play

While previewing the new stuff at this year's PGA Show coming up this week, Jeff extolls the virtues of the new Titleist AP irons. Whether the AP1, AP2, or AP3, one will be perfect for you, no matter how well you do or do not play

News Is the new Last of Us 2 trailer TOO violent? Rumored Superman game coming from Rocksteady. Pub G has it’s preview program release date for 12/12/17 and will cost $30 for the preview. Shadow of Colossus got a release date of 2/5/18 $46K PS4 bundle sold in Tawaiin. PS4, PS plus membership for a year, PS-VR, Thrust Master Racing wheel, APIGA, AP1 racing seat, 4K sony TV, copy of grand torrismo sport, and a freaking car.  Kevin Spacey is probably leaving house of cards. Or they’re just gonna cancel it. But they aren’t going forward w/it. Apparently we’re getting an infinity war trailer by end of year. Fan Made Pickle Rick game removed from Steam, check out gameplay here - https://www.polygon.com/2017/11/3/16600350/rick-and-morty-piccled-ricc-steam-valve-pewdiepie-jim-sterling Rick & Morty co-creators started a podcast - https://www.polygon.com/2017/11/2/16598514/rick-morty-podcast-dan-harmon-jessica-gao-white-wongs Main Topics Super Mario Odyssey ( gameplay - https://www.youtube.com/watch?v=hUObvU9A_Cg ) Assassins Creed: Origins (gameplay - https://www.youtube.com/watch?v=A9OxAkVlZC0) Wolfenstein II: The New Colossus (gameplay - https://www.youtube.com/watch?v=gdR2obbtP7s)   Glitch Therapy is a video game podcast where we geek out in the latest in gaming news and culture.   Questions? Email us at GlitchTherapy@gmail.com   Want to keep listening to the show? Head on over to www.Patreon.com/glitchtherapy and donate at least $1 a month to get access to our post show that we do after every episode.   Music: "Memory" by Creo From the Free Music Archive CC BY ND   Thanks so much for listening, game on!

President of Titleist Golf, Steve Pelisek, joins us for episode #249 of the Worldwide Golf Shops Insider Podcast to introduce the new Titleist 818 line of hybrids and the distance iron side of the new 718 line in the 718 T-MB, 718 AP1, and 718 AP3. In the second part of this episode, we discuss the 818 H1 and H2 hybrids, the 718 T-MB, 718 AP1 and 718 AP3 irons, the different shapes and looks of the hybrids, how these clubs can benefit your game, what players are using on tour, how Titleist puts a new spin on these scoring clubs, and how who can benefit most from the new 818 line. Take a listen to our podcast and visit a Worldwide Golf Shops location near you to try out the 718 & 818 lines from Titleist.

Titleist 718 AP3, AP1, T-MB Irons Review compares the three 718 distance irons to find out which one is best for your game.

Daniel and Vincent solve the case of the Woman With Anal Area Discomfort, and discuss the multiple functions of a clathrin adapter protein in formation of rhoptry and microneme secretory organelles of Toxoplasma gondii. Hosts: Vincent Racaniello and Daniel Griffin Become a patron of TWiP. Links for this episode: Journal of Microbiology and Biology Education SciComm Issue (link) TWiP 19: Enterobius vermicularis, the pinworm Multiple roles of Toxoplasma gondii clathrin adaptor AP1 protein (PLoS Path) Image credit Letters read on TWiP 133 Case Study for TWiP 133 Seen while working in remote mountain makeshift mobile clinic in Dominican Republic, on Haitian border. Traveled 3 h by pickup truck, remote mountain town, womens centers. Set up makeshift mobile clinic in this center. Mother concerned about 6 yo girl, failure to thrive compared with sister, protuberant belly, frequent abdominal discomfort, going on over 1 year. No surgeries, no meds, first time ever seeing medical person. Mother and sister are family. Three children in family. Father does timber work. Very impoverished region, living in dirt floor home, drinking untreated water from local stream, go to bathroom outside, could be contamination. Diet: carbohydrate, plantains, rice, beans. On exam: lungs clear, heart fine, belly protuberant, liver and spleen not enlarged, some edema. Mother said noticed long motile worm in girls feces. Firm belly, not painful to her. Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees

Titleist 716 AP2 Irons Review reveals how additional tungsten lowers the CG to give a better performing AP1 and AP2.

In this special episode of the podcast, I (Matt) premiere my solo side-project podcast: Anthology. In this pilot episode, I introduce the concept for the podcast, its origin, and give some background on The Twilight Zone and my feelings about the show. I also review and analyze The Twilight Zone's first two episodes: Where is Everbody? & One for the Angels. Anthology will be added to iTunes soon. For now, like the Facebook Page and visit the homepage at http://anthologypod.com. Tweet me your thoughts on the podcast and The Twilight Zone itself @ObsessiveViewer. You can also reach me on Anthology's Facebook Page, email me at Matt(at)ObsessiveViewer(dot)com, or call and leave a voicemail for the show: (317) 762-6099. Runtime: 1:00:20   Direct Download Link: http://traffic.libsyn.com/anthologypod/AP1.mp3 Stream it here: http://directory.libsyn.com/episode/index/id/3711140   Timestamps Matt Custom Intro - 0:00 Introduction - 4:23   Where Is Everybody? - 18:05 Shocktober in Irvington Promo - 38:57 One For the Angels - 40:00   Outro - 57:25   Show Notes Obsessive Viewer Podcast - This week's promo clip came from The Obsessive Viewer podcast episode 112 - TV Second Seasons and Our 2-Year Podcast Anniversary Facebook: AnthologyPod - Like Anthology on Facebook Twitter: @ObsessiveViewer - Tweet me your thoughts on the show Anthology's Full Episode Archive Anthology's RSS Feed Obsessive Viewer Subreddit Obsessive Viewer - Check out plenty of reviews of movies, TV shows and industry commentary at the blog that started it all. Obsessive Book Nerd - Our “sister site” where you can find book reviews and commentary on the evolving world of reading.    

Golfalot Review the Titliest 712U Hybrid Iron

Golfalot Review the Titliest AP1 714 Irons

Golfalot Review the Titleist 712 AP1 AP2 Irons

Melanosomes are specialized pigment-producing organelles that arise from the endosomal system. A new study reveals that the clathrin adaptor AP-1 and the kinesin motor KIF13A combine to sort melanosomal cargo and position endosomes near to developing melanosomes where they deliver the cargo via direct tubular contacts. This biosights episode presents the paper by Delevoye et al. from the October 19th, 2009 issue of the Journal of Cell Biology, and includes interviews with authors Graça Raposo and Cédric Delevoye. Produced by Eun Choi and Ben Short. Subscribe to biosights via iTunes or RSS View biosights archive The Rockefeller University Press biosights@rockefeller.edu

Golfalot Review the Titleist 710 AP1 and AP2 Irons

Background: Total tau (T-tau) and beta-amyloid((1-42)) (A beta(1-42)) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia. Differential diagnosis from dementia with Lewy bodies (DLB) in clinical settings is difficult. Methods: The analytical performance of the INNOTEST (R) PHOSPHO-TAU((181P)) assay was validated in terms of selectivity, sensitivity, specificity, precision, robustness, and stability. Clinical utility of the assay alone, or combined with T-tau and AP1-421 for discrimination of AD (n=94) from patients suffering from DLB (n=60) or from age-matched control subjects (CS) (n=60) was assessed in a multicenter study. Results: CSF concentrations of tau phosphorylated at threonine 181 (P-tau(181P)) in AD was significantly higher than in DLB and CS. Discriminant analysis, a classification tree, and logistic regression showed that P-tau(181P) was the most statistically significant single variable of the three biomarkers for discrimination between AD and DLB. Conclusions: P-tau(181P) quantification is a robust and reliable assay that may be useful in discriminating AD from DLB.

Pathogenetische Bedeutung der induzierbaren Stickstoffmonoxid-Synthase für den akuten hyperoxischen Lungenschaden Die längere Applikation von Sauerstoff in höheren Konzentrationen führt zu einer oxidativen Schädigung der Lunge. In den letzten Jahren gab es auch Hinweise darauf, dass Stickstoffmonoxid (NO), produziert durch die induzierbare NO-Synthase (iNOS), an der Pathogenese des hyperoxischen Lungenschadens beteiligt sein könnte. Ziel der Studie war es, die Beteiligung von NO an der Entstehung des akuten Lungenschadens unter Hyperoxie in vivo zu untersuchen. Dazu wurden unter standardisierten, experimentellen Bedingungen iNOS-defiziente und Wildtyp-Mäuse erhöhten Sauerstoffkonzentrationen (60 und 100 %)über 24 bzw. 72 h ausgesetzt. Die Ergebnisse zeigen, dass nach 72 h unter 100 % Sauer-stoff sowohl in der Wildtyp- als auch in der iNOS-defizienten Gruppe ein deutlich vermehrter Zellschaden im Sinne einer Abnahme der Zellvitalität und einer Zunahme der LDH-Aktivität auftritt. Als Zeichen einer verstärkten inflammatorischen Reaktion kam es zu einer Erhöhung der Gesamtzellzahl und -proteinkonzentration in der Bronchiallavageflüssigkeit sowie zu einer vermehrten TNF-alpha-Expression, welche durch die Transkriptionsfaktoren NF-Kappa B und Aktivatorprotein 1 (AP1) vermittelt wurde. Diese Auswirkungen waren auch in den histologischen Schnitten zu beobachten. Als Zeichen vermehrten oxidativen Stresses war eine erhöhte Lipidperoxidation zu verzeichnen. Die genannten Beobachtungen waren bei den Wildtyp-Mäusen wesentlich ausgeprägter als bei den iNOS-defizienten Tieren, was auf die erhöhte iNOS-Expression zurückgeführt werden könnte. Aus der Gesamtheit der Daten lässt sich schliessen, dass unter akuter Hyperoxie die proinflam-matorische Komponente der iNOS zu überwiegen scheint, dadurch wird das Ausmaß der inflammatorischen Reaktion und die resultierende Lungenschädigung potenziert.

EBV is a γ-herpes virus which is able to infect human resting B-cells and to transform them into permanently growing lymphoblastoid cell lines (LCLs). EBNA2 (Epstein-Barr virus nuclear antigen 2) is one of the first viral proteins expressed after in vitro infection and interacts with different cellular proteins like RBP-Jκ and PU.1. The EBNA2 protein acts as a transcriptional activator of the viral Latent Membrane Proteins 1 and 2 (LMP1 and LMP2) and the viral nuclear genes EBNA1, EBNA3A, -3B, -3C, EBNA-LP. Additionally EBNA2 is also able to transactivate cellular genes like CD21, CD23 or c-myc. To study the different EBNA2 target genes and the function of EBNA2 a LCL was established (ER/EB2-5 cells, Kempkes et al., 1995) harboring an estrogen-inducible EBNA2. In the presence of estrogen the ER/EBNA2 fusion protein (estrogen receptor binding domain) is located in the nucleus were EBNA2 can transactivate its target genes, whereas in the absence of estrogen the ER/EBNA2 fusion protein is kept in the cytoplasm and therefore inactive. The cells proliferate in the presence of estrogen and they arrest in the absence resulting in a phenotype similar to resting B-lymphocytes. By using the ER/EB2-5 cell line I could clearly show that the cell surface molecule CD83, belonging to the immunoglobuline superfamily (Zhou et al., 1992), is upregulated after the activation of EBNA2. By using a derivative ER/EB2-5 cell line that constitutively expressed LMP1 I could show that CD83 is still expressed even in the absence of functional EBNA2 suggesting that LMP1, the viral target gene of EBNA2, is responsible for the induction of CD83. Therefore I analysed the activation of the CD83 promoter by LMP1. LMP1 is a transmembrane protein with a short intracellular N-terminus, 6 hydrophobic transmembrane domains and a long intracellular C-terminus, containing C-terminal activator regions CTAR1, 2 and 3. The different CTAR regions are responsible for activating genes via NF-κB, ATF, AP1 and STAT signaling pathways. For the activation of its target genes LMP1 uses the same signaling molecules (TRAF, TRADD) as family members of the TNF-R family (CD40, TNF-R1, TNF-R2). The CD83 promoter was activated by LMP1 as shown by promoter luciferase reporter assays in 293-T cells. The induction was not observed in the absence of a NF-κB binding site in a CD83 promoter mutant. Furthermore LMP1 mutants which are mutated in the binding regions for TRAF2 (CTAR1) or TRADD (CTAR2) are not able to transactivate the CD83 promoter. By co-transfection of LMP1 and dominant/negative IκB the CD83 promoter could not be activated because of inactivation of NF-κB. These experiments clearly demonstrate that the CD83 promoter is transactivated by LMP1 via NF-κB. Additionally to the regulation of CD83 I was also interested in the functional role of CD83. Until now only little is known about the function of CD83. CD83 seems to have a specific role in the decision to single positive CD4+ T-cells in the thymus (Fujimoto et al., 2002). I have tested a possible co-stimulatory function of CD83 to CD4+ T-cells by retroviral expression of CD83 in non-professional antigen presenting cells (RCC). Indeed CD83 expression increased the CD4+ response in comparison to CD80 or GFP retroviral infected RCC cells. In mixed lymphocyte reactions this co-stimulatory effect could not be clearly demonstrated although a soluble CD83-Ig showed a small inhibitory influence. The identification of a CD83 ligand molecule could give new insights into the function of CD83. Therefore a CD83-Ig fusion protein as well as a CD83-tetramer construct were generated and used to screen for a potential ligand of CD83. First results showed that the CD83-Ig fusion protein and the CD83-tetramer construct bound to CD4+ and to CD8+ T-cells of isolated PBMCs as well as to activated T-cells in a culture of mixed T-cell populations.