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Marre de vendre ton temps ? Tu plafonnes en revenu freelance ? Tu veux scaler sans t'épuiser ?Dans cet épisode, je te montre 7 façons de pricer pour ne plus jamais facturer au TJM.➡️ Tu n'as pas le temps de prospecter pour ton activité de freelance ? Découvre l'outil Cli3nts pour prospecter à ta place sur Linkedin!
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Después de toda la polémica del partido de la final de futbol salvadoreño, estuvimos al aire para hacer un enlace con "Tiro Libre" con Roberto Bundio y Alex Pineda.
durée : 03:03:26 - Les Nuits de France Culture - par : Albane Penaranda - En 1995, l'émission "Vladimir Jankélévitch : un homme libre" propose un hommage au philosophe disparu dix auparavant. Ses proches, ses élèves, et lui-même, grâce aux archives, témoignent d'une pensée et d'une vie singulière. Une émission de Christine Goémé diffusée en juin 1995. - réalisation : Antoine Larcher - invités : Vladimir Jankélévitch Philosophe (1903-1985); André Comte-Sponville Philosophe français; Laurence Hansen-Love Professeure agrégée de philosophie, spécialiste de philosophie politique et morale; Robert Maggiori Philosophe, journaliste de "Libération" et co-fondateur et président du Jury des Rencontres philosophiques de Monaco
L'Europe qui avance aussi du côté de Canberra où l'accord de libre-échange est remis sur la table après la rencontre post-papale entre von der Leyen et Albanese
durée : 00:59:07 - Entendez-vous l'éco ? - par : Aliette Hovine, Bruno Baradat - Entre 1850 et 1914, le monde s'ouvre aux échanges comme jamais auparavant, porté par le libéralisme anglais. Mais cette première mondialisation, dont l'acmé est le Traité de Cobden-Chevalier en 1860 entre la France et l'Angleterre, est en réalité inégale et encadrée par des États puissants. - réalisation : Françoise Le Floch - invités : Léo Charles Maître de conférences en sciences économiques à l'Université de Rennes 2 ; David Todd Professeur d'histoire à Sciences Po Paris et chercheur associé au Centre for History and Economics à l'université de Cambridge
Este episodio no es una guerra contra el alcohol.Es una declaración de amor hacia mí.Te comparto desde mi parte más honesta y vulnerable por qué decidí iniciar un reto de 100 días sin alcohol.No porque sea malo, sino porque ya no va con la mujer en la que me estoy convirtiendo.No me considero abstemia, me considero libre.Libre de necesitar algo externo para relajarme, pertenecer o disfrutar.Libre de esa copa que se había vuelto una muleta social.Aquí te cuento cómo me he sentido en estos primeros días, qué he descubierto sobre mí, cómo afecta el alcohol a tu sistema nervioso y a tu capacidad de manifestar... y por qué hoy, desde el amor propio, digo:“Hoy no brindo con vino… brindo por mí.”
Audio Devocional "Crezcamos de Fe en Fe" - Ministerios Kenneth Copeland
«Cristo nos redimió de la maldición de la ley, y por nosotros se hizo maldición (porque está escrito: «Maldito todo el que es colgado en un madero»)» (Gálatas 3:13) Tú ya sabes lo que pasó: Satanás, en forma de serpiente, se le acercó a la esposa de Adán y la engañó para que desobedeciera a Dios. Aunque Adán no fue engañado, hizo lo mismo que ella. Ese día, cuando Satanás vino al huerto, no tenía ningún poder. Tuvo que entrar sigilosamente, sin hablar de manera directa con Adán, sino con su esposa. Adán estaba allí, y debió haberlo echado fuera. Pero no lo hizo. En vez de eso, desechó el mandato que Dios le había dado y obedeció a Satanás; y cuando lo hizo, Satanás se convirtió en su señor. Al doblar su rodilla ante Satanás, Adán le otorgó la autoridad que Dios le había conferido al hombre. Él hizo a Satanás el gobernador ilegítimo de la Tierra. Las cosas cambiaron de inmediato. El pecado entró al mundo por un hombre, y por el pecado, la muerte; así la muerte pasó a todos los hombres (Romanos 5:12). De repente, la Tierra y todo lo que había en ella fueron malditos. Quizás digas: “Entiendo. ¿Vamos a vivir bajo esa maldición el resto de nuestra vida? ¿No había nada que Dios pudiera hacer?” ¡Sí lo había, y lo hizo! Él envió a Jesús. Gracias a Jesucristo Dios nos libró de la maldición (Gálatas 3:13). Tú fuiste rescatado del señorío de Satanás en el momento en que hiciste a Jesucristo el Señor de tu vida. Fuiste redimido de la maldición. No dije que la maldición ya no está allí afuera. De hecho, lo está. Puedes verla a tu alrededor. Pero ahora tienes una opción. Posees autoridad sobre ella en el nombre de Jesús, y puedes resistirla. Dios ya ha hecho todo lo que el amor puede hacer. Envió a Jesús para redimirte de la maldición. El resto está en tus manos. Ahora debes apropiarte de lo que ha sido creado para ti. Lectura bíblica: Romanos 5:12-21 © 1997 – 2019 Eagle Mountain International Church Inc., también conocida como Ministerios Kenneth Copeland / Kenneth Copeland Ministries. Todos los derechos reservados.
Cette semaine, la 5e de Couv’ vous propose une libre antenne manga. Louvoyant entre les ponts du mois de mai, nous prenons le temps de savourer les nouveautés (comme Tower Dungeon par exemple). Mais on... L'article Libre antenne – La 5e de Couv – #5DC – Saison 10 épisode 35 est apparu en premier sur La 5e de Couv' - Le podcast de débat autour du manga !.
« Contrairement à ce qu'on peut penser, Feydeau c'est une écriture très fine et très aigüe, avec des mécaniques de précisions incroyables. C'est un très bon exercice pour le metteur en scène de se confronter à ces structures implacables, qui vous obligent à travailler différemment et à revenir à la compréhension de la narration d'une histoire. Avant de faire rire, Feydeau raconte des histoires. » L'Hôtel du Libre-Échange, c'est une nuit de quiproquos, de rendez-vous ratés, d'amours escamotés et d'infidélités consommées... Vingt ans après avoir mis en scène La Puce à l'oreille, Stanislas Nordey retrouve l'univers de Georges Feydeau avec l'une de ses œuvres majeures. Cette production réunit sur la scène du Théâtre de l'Odéon à Paris une troupe de quatorze comédiens et commédiennes hors pair - un nombre important et apprécié - dont Hélène Alexandridis, Marie Cariès, Claude Duparfait ou encore Cyril Bothore. Invité : Stanislas Nordey, comédien et metteur en scène. « L'hôtel du libre-échange » est à voir au Théâtre de l'Odéon jusqu'au 13 juin 2025.► Pour approfondir les thèmes abordés dans la pièce, un séminaire intitulé « Genre, sexualité et vaudeville » est organisé le mercredi 21 mai 2025 à 18h00 au Salon Roger Blin de l'Odéon. Ce séminaire, en partenariat avec Sorbonne Université, réunira des experts pour discuter des questions de genre et de sexualité dans le contexte de la pièce.► Pour en savoir plus sur le parcours de Stanislas Nordey, un livre d'entretiens avec Fréderic Vosier : Stanislas Nordey, Locataire de la parole publié aux Solitaires intempestifs.La programmation musicale : ♦ « Clair de Lune », Pierre Kwenders ft Pierre Lapointe & NegoO.
CNTE anuncia que el lunes permitirán el libre tránsito en algunas casetasMiles de personas se manifiestan en La Haya para reclamar medidas frente a IsraelMás información en nuestro Podcast
Pint of Science et Les mystères de lʹUNIL Les brèves du jour Lʹhistoire évolutive des lémuriens Notre libre arbitre est-il réellement libre?
durée : 00:07:39 - Le Masque et la Plume - L'Hôtel du libre-échange de Feydeau revisité par Stanislas Nordet : une proposition audacieuse qui divise. Modernité et accessibilité pour certains, contresens et langue phagocytante pour d'autres. Une mise en scène à découvrir à l'Odéon.
durée : 00:48:08 - Le Masque et la Plume - par : Rebecca Manzoni - Une nuit mouvementée dans un hôtel discret ; l'adaptation de Shakespeare par le Munstrum Théâtre ; le stand-up d'Umut Köker autour de ses origines ; Un mariage à Beyrouth dans les années 70 en pleine guerre ; une parodie musicale queer du film Titanic ; un cabaret qui adapte l'auteur Hanokh Levin. - invités : Laurent Goumarre, Pierre Lesquelen, Sandrine Blanchard, Fabienne Pascaud - Laurent Goumarre : Producteur de radio français, journaliste au quotidien Libération, Pierre Lesquelen : Critique à I/O Gazette et Détectives sauvages, dramaturge et enseignant-chercheur, Sandrine Blanchard : Journaliste et critique pour Le Monde, Fabienne Pascaud : Journaliste chez Télérama - réalisé par : Guillaume Girault
Nous sommes aujourd'hui avec Amandine Chaignot, une cheffe libre et talentueuse qui respire la joie de vivre. Passionnée par le terroir et la nature, elle partage désormais sa vie entre ses adresses parisiennes, Pouliche et le Café de Luce, et sa toute nouvelle auberge nichée au cœur du Perche. Pour co-animer ce nouvel épisode de Business of Bouffe, Philibert est accompagné de Samir Ouriaghli, sourceur d'épices et fondateur d'Ankhor.À travers ce podcast, nous cherchons à comprendre comment Amandine, après avoir fait ses armes auprès des plus grands chefs, a pris son indépendance pour exprimer son propre style et créer des lieux singuliers qui lui ressemblent.Pour cela, on prend évidemment le temps de revenir sur son parcours atypique. Issue d'un milieu académique, et après une formation scientifique, c'est un job de serveuse dans une pizzeria qui éveille sa passion pour la cuisine. Malgré sa vocation tardive, Amandine vise les sommets et enchaîne avec brio les expériences dans les plus beaux palaces parisiens auprès de Jean-François Piège, Eric Frechon ou encore Yannick Alléno.Puis c'est le grand saut vers l'indépendance : Amandine nous raconte l'ouverture de Pouliche et du Café de Luce, ses propres restaurants parisiens. Avec ses deux associés Pierre-Julien et Grégory Chantzios (Kalios, Eleni Group), elle crée des restaurants à son image où elle affirme enfin son style : une cuisine exigeante, instinctive et responsable. En 2024, elle va encore plus loin et elle rénove, avec l'aide de tout un village, une ancienne bâtisse percheronne pour en faire un lieu de vie campagnard, à la fois bistrot convivial et table gastronomique.Cet épisode a été enregistré avec la participation exceptionnelle de Nina Métayer, Émeline Aubry, Bernard Leprince et Pierre-Julien Chantzios. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Chapingo inaugura exposición sobre la milpa y plantas ancestrales de México Rosa Icela asistirá a ceremonia del Papa León XIV en El VaticanoPapa León XIV pide dignificar a migrantesMás información en nuestro podcast
El programa semanal de mundoplus.tv donde hablamos de las plataformas de streaming, televisión de pago y todo lo parecido. En el nuevo formato intercalamos rumores, consultas y divagaciones entre las noticias así que para no perderte nada recomendamos ver el programa entero, pero así como destacados en el programa de hoy: 0:00:00 - Inicio, Presentación, Comentarios y Preguntas del Chat - Movistar Plus+ consigue el mayor aumento de abonados en 3 años - Disney+ baja de precio para clientes de Movistar Plus+ - Netflix alcanza 94 millones de usuarios con anuncios y lanza su propia plataforma publicitaria - La NBA llega a Prime Video en España - Warner Bros. Discovery recupera la marca HBO Max para su plataforma de streaming - Estos son los cuatro canales que acaba de añadir Orange TV Libre - SkyShowtime lanza una promoción del 40% - LaLiga adjudica a Dazn el partido en abierto durante las dos próximas temporadas - Más noticias en mundoplus.tv - Divagaciones varias, conclusiones y despedida FIN Este programa se graba en directo todos los Jueves a las 21H en nuestros canales de Twitch y YouTube [ / mundoplustv ]( / mundoplustv ) y [ / @mundoplustv ]( / @mundoplustv ) anímate a participar en el directo.
Dicen que en el amor todo se vale… ¡hasta dejar que tu pareja se acueste con alguien más si tú no puedes cumplirle! ¿Te suena loco o eres de los que ya vive en modo open mind? En este episodio de El Bueno, La Mala y El Feo hablamos de las relaciones donde uno da permiso para que el otro busque fuera lo que en casa no encuentra. ¿Es amor moderno o ya es pasarse de lanza? ¡Prepárate porque este tema viene con fuego, pelos y señales! Mantente al día con los últimos de 'El Bueno, la Mala y el Feo'. ¡Suscríbete para no perderte ningún episodio!Ayúdanos a crecer dejándonos un review ¡Tu opinión es muy importante para nosotros!¿Conoces a alguien que amaría este episodio? ¡Compárteselo por WhatsApp, por texto, por Facebook, y ayúdanos a correr la voz!Escúchanos en Uforia App, Apple Podcasts, Spotify, y el canal de YouTube de Uforia Podcasts, o donde sea que escuchas tus podcasts.'El Bueno, la Mala y el Feo' es un podcast de Uforia Podcasts, la plataforma de audio de TelevisaUnivision.
Entre Libros 002 Cómo Ser Una Mujer Libre en Cristo - Cynthia Heald by CCRTV
Entre Libros 003 Cómo Ser Una Mujer Libre en Cristo - Cynthia Heald by CCRTV
Entre Libros 004 Cómo Ser Una Mujer Libre en Cristo - Cynthia Heald by CCRTV
Stoppé par la justice, le chantier contesté de l'autoroute A69 Toulouse-Castres pourrait bien être relancé grâce au Parlement. Ce jeudi, le Sénat a voté largement une proposition de loi en ce sens. Écoutez la réaction de Geoffrey Tarroux, porte-parole de l'association "La Voie est libre". Ecoutez L'invité pour tout comprendre avec Yves Calvi du 15 mai 2025.Distribué par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
Stoppé par la justice, le chantier contesté de l'autoroute A69 Toulouse-Castres pourrait bien être relancé grâce au Parlement. Ce jeudi, le Sénat a voté largement une proposition de loi en ce sens. Écoutez la réaction de Geoffrey Tarroux, porte-parole de l'association "La Voie est libre". Ecoutez L'invité pour tout comprendre avec Yves Calvi du 15 mai 2025.Distribué par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
¿Has salido alguna vez de un buffet con el vientre tenso como tambor de guerra, preguntándote en qué momento perdiste el control? Tranquilo, no fue un desliz personal. Fue una emboscada. En el episodio 195 del podcast de Keto Real, desenmascaramos al buffet moderno: ese templo del “todo incluido” que, paradójicamente, incluye sobrepeso, inflamación y un leve sentimiento de derrota.
El primer trimestre de 2025 experimentó un decrecimiento interanual de un 29.3% respecto al número de vacacionistas extranjeros. Sus 4 principales países emisores se contrajeron Canadá bajó un tercio y Rusia la mitad, según cifras oficiales.
Gerardo Ortega, de gerardoortega.es y analista jefe en Trive, repasa las cotizaciones de Mapfre, IAG, Microsoft, Telefónica y Siemens Energy
learn how to say 'free' in French
durée : 00:23:29 - Les goûts d'ici en Béarn Bigorre - La fédération de la Boulangerie des Pyrénées Atlantiques organise la Fête du pain 2025 cette semaine au sein de quartier libre à Lescar.
Milei ha revolucionado Argentina, pero ¿es suficiente para Hispanoamérica? En este episodio, analizamos cómo las ideas de la Escuela Austríaca y las enseñanzas de Salamanca están dando forma a un futuro económico diferente. Sin embargo, hay dos barreras clave: la falta de industria propia y la debilidad de una Hispanoamérica dividida. ¡Escucha el análisis completo y comparte tu opinión!❌ X: x.com/ConstanDeMiguel
Milei ha revolucionado Argentina, pero ¿es suficiente para Hispanoamérica? En este episodio, analizamos cómo las ideas de la Escuela Austríaca y las enseñanzas de Salamanca están dando forma a un futuro económico diferente. Sin embargo, hay dos barreras clave: la falta de industria propia y la debilidad de una Hispanoamérica dividida. ¡Escucha el análisis completo y comparte tu opinión!❌ X: x.com/ConstanDeMiguel
Los especialistas de ESPN debaten sobre la idoneidad de quien parte como favorito para ser el nuevo técnico del Real Madrid. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Tenemos Papa, León XIV, que sigue la estela de Francisco que concebía la Iglesia como un hospital de campaña. Y hace unas semanas en un hospital de campaña, en la parroquia de Santa Anna en pleno centro de Barcelona. Allí conocemos las historias terribles de 3 mujeres que llegaron huyendo de la violencia de sus países y encontraron aquí la explotación y el maltrato. La otra cara de la Iglesia es el poder económico. En España la iglesia es la principial inmobiliaria del país. Hablamos con Asunción Villaverde de Europa Laica para repasar los beneficios fiscales que tiene y otros abusos. Acabamos escuchando a voluntarios del Banco de Alimentos de Madrid, se necesita 25 mil voluntarios para la campaña de recogida de final de mayo
El programa semanal de mundoplus.tv donde hablamos de las plataformas de streaming, televisión de pago y todo lo parecido. En el nuevo formato intercalamos rumores, consultas y divagaciones entre las noticias así que para no perderte nada recomendamos ver el programa entero, pero así como destacados en el programa de hoy: 0:00:00 - Inicio, Presentación, Comentarios y Preguntas del Chat - Max crece en número de suscriptores durante el primer trimestre del año - Orange TV Libre, la nueva televisión por streaming abierta a todos por solo 7,99€/mes - Fútbol y Fórmula 1 impulsan las audiencias de la televisión de pago en España - Netflix estrena diseño renovado, recomendaciones dinámicas y búsqueda avanzada - Más noticias en mundoplus.tv - Divagaciones varias, conclusiones y despedida FIN Este programa se graba en directo todos los Jueves a las 21H en nuestros canales de Twitch y YouTube [ / mundoplustv ]( / mundoplustv ) y [ / @mundoplustv ]( / @mundoplustv ) anímate a participar en el directo.
La verdadera libertad no es ausencia de problemas, es vivir bajo la sangre del Cordero. Jesús no solo te salvó del pecado, también te rompió el yugo de esclavitud. Hoy puedes vivir sin temor, sin opresión, sin cadenas. Solo necesitas pararte firme en la libertad que Él ya conquistó para ti.
durée : 02:02:04 - Les Nuits de France Culture - par : Philippe Garbit - Par Twefik Hakem - Avec Radouane Ainad Tabet, Jean Amrouche, Annie Rey-Goldzeiguer, Bachir Boumaza, Yacine Kateb, Ferhat Abbas, Daho Djerbal, Mehdi Lalaoui, Edwy Plenel, Jean Daniel et Mohammed Harbi - Réalisation Laurent Rousseaux - réalisation : Mydia Portis-Guérin
It's a major milestone as Steven and Shaun hit their 1000th episode of Double Tap! In this special edition, they're joined by executive producer Marc Aflalo for a surprise celebration packed with heartfelt tributes from major names across the accessible tech world. You'll hear messages from Amos Miller (Glidance), Mike Buckley (Be My Eyes), Kelly MacDonald (AMI), and even Chris Patnoe from Google and of course Mr. F.But that's not all — Steven delivers an impassioned rant about the state of radio in 2025. From inaccessible DAB radios to smart speakers demanding sign-ins, he questions why a traditionally blind-friendly medium has become so complicated. The conversation then shifts to digital ownership, AI tools like Gemini and Copilot, and how listener feedback shapes every episode. Expect laughs, honesty, and a deep appreciation for community in this milestone moment.Chapter Markers00:00 – Introduction02:10 – Surprise video: Messages from Glidance, Be My Eyes, Google & more06:30 – Reflections on what Double Tap has become09:00 – Steven's full-blown rant on radio accessibility12:30 – Why DAB and smart speakers fail blind listeners18:20 – The problem with owning digital media in 202521:45 – Resurgence of DVDs & physical media explained26:30 – When power goes out: The critical case for accessible radios28:45 – Listener Scott asks about TalkBack on Samsung35:30 – Gemini Live: Using AI with your camera40:20 – Carl's diabetes accessibility tips for CGMs47:30 – Libre app, Sweet Dreams, and audiographs explained49:45 – Larry shares a simple iOS app library tip51:00 – Renée asks: How do you know a site is inaccessible?54:00 – The web is a Wild West for screen reader users56:00 – Final reflections and thank yous from Steven and Shaun Find Double Tap online: YouTube, Double Tap WebsiteJoin the conversation and add your voice to the show either by calling in, sending an email or leaving us a voicemail!Email: feedback@doubletaponair.comPhone: 1-877-803-4567
Entre Libros 001 Cómo Ser Una Mujer Libre en Cristo - Cynthia Heald by CCRTV
durée : 00:48:28 - Affaires sensibles - par : Fabrice Drouelle, Franck COGNARD - Aujourd'hui dans Affaires sensibles, la commune libre de Christiania à Copenhague - réalisé par : Frédéric Milano
Tous les matins à 7H10 et 9h45, on vous donne des bonnes nouvelles.
A veces sabemos que para que nuestra vida se transforme, debemos cambiar nuestros pensamientos. En este programa RevAna entrevista a Cristina Bonnet, coach de bienestar emocional que integra la ciencia y espiritualidad en el proceso de transformación
Beisbol de Grandes Ligas a pulso
Can you really manage diabetes accessibly as a blind user? In this powerful episode, Shaun dives into the search for an accessible blood glucose monitor—and gets an eye-opening response from Tess Lockton, a visually impaired parent of a child with type 1 diabetes. From the frustrating reality of so-called “talking monitors” to the pros and cons of continuous glucose monitors like Dexcom and Libre, Tess shares hard-earned insights every listener needs to hear.Also in this episode: Steven and Shaun talk Eero mesh networks, gigabit internet, and Sky Glass, before diving into your feedback on navigation tech, including a thoughtful message about GPS and accessibility from listener Doug.[Episode Summary]Shaun shares his struggles managing type 2 diabetes as a blind person and kicks off a deeper conversation about accessible diabetes tools. Listener Tess Lockton joins to discuss raising a child with type 1 diabetes while visually impaired—and how the tech designed to help often falls short. She breaks down her experiences with Dexcom and Libre systems, the challenges of getting accurate readings, and why even the best tech solutions still leave accessibility gaps.Meanwhile, Steven updates his home setup with Sky Glass and talks through the accessibility differences between SkyQ and the new system. The duo also nerd out over mesh networking and smart speakers—and highlight new listener feedback on GPS tech like StellarTrek and the missed potential of Soundscape-style navigation.[Chapters]0:00 – Shaun's glucose journey begins3:40 – Weekend updates: Eero mesh fixes and gigabit drama9:55 – Sky Glass, audio description, and setup accessibility18:10 – Double Tap's new newsletter partnership with Mindvault22:04 – Listener Tess Lockton joins to talk accessible diabetes tech24:20 – Living through diagnosis and hospital mishandling31:05 – Dexcom vs Libre: pros, cons, and accessibility flaws40:15 – Finger-prick demo: Why even “accessible” monitors fail52:10 – The hidden costs and pressure of using inaccessible tools56:30 – Final advice and offers of help from Tess[Relevant Links]Double Tap Newsletter: https://doubletaponair.com/subscribeNexus Voice Talking Blood Glucose Monitor: https://www.glucorx.co.uk/shop/nexus-voice-meter/Dexcom Continuous Glucose Monitoring: https://www.dexcom.comFreestyle Libre 3 System: https://www.freestyle.abbott/en-ca/products/what-is-free-style-libre.htmlRNIB (Royal National Institute of Blind People): https://www.rnib.org.uk
Inicia reparto de fertilizantes gratuitos en CDMX Marcha en favor de legalización de la mariguana De cara al Cónclave cardenales intensifican sus encuentros Más información en nuestro podcast
It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: A new Austrailian study aims to prevent type 1, the new twiist pump will integrate with Eversnse CGM as well as Libre, diabetes deaths are down in the US, Dexcom U is looking for college athletes, and more! Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX A world-first human trial of a drug designed to treat the underlying cause of type 1 diabetes has begun in Australia. University of Queensland researcher Ranjeny Thomas said the experimental drug — dubbed ASITI-201 — was designed to retrain the immune system so it no longer attacks the insulin-producing pancreatic cells, known as beta cells. The drug, given as an injection under the skin, combines fragments of a protein found in the beta cells of people with type 1 diabetes and vitamin D to calm the immune response. She said if effective, the drug would initially be given to patients with type 1 diabetes as soon as possible after diagnosis to preserve remaining pancreatic cells and reduce the amount of insulin needed. But eventually, if screening programs can be developed to pick up people at risk of developing type 1 diabetes, it may be possible to "prevent the progression of the disease altogether". The first in-human trial of 36 participants will test the safety of the drug, but blood tests will also determine the impact of the therapy on a patient's immune system and glucose tolerance. https://www.abc.net.au/news/2025-04-29/type-1-diabetes-drug-trial-auto-immune-disease-science/105223022 XX Diabetes deaths in the U.S. have fallen to some of the lowest rates in years, according to new preliminary figures published by the Centers for Disease Control and Prevention, reversing a surge in mortality that was seen during the COVID-19 pandemic. There were 26.4 deaths per 100,000 people from diabetes, according to early death certificate data for the third quarter of 2024 published this month by the CDC's National Center for Health Statistics. Death rates from diabetes peaked in 2021, according to CDC figures, at 31.1 deaths per 100,000 people for that year. Diabetes was the eighth leading cause of death in 2021. The CDC says the link between COVID-19 and diabetes may be to blame for that increase. "Data show an increase in mortality rates for all people during the COVID-19 pandemic, and research shows that people with underlying conditions, including diabetes, are more likely to become very sick from COVID-19 and have a higher risk of hospitalization and death," Christopher Holliday, head of the CDC's Division of Diabetes Translation, told CBS News in a statement. Holliday added that research shows the pandemic may also have made it harder for Americans to properly manage the disease, ranging from interruptions to physical activity to disruptions to routine medical care diagnosing and treating the disease. https://www.cbsnews.com/news/diabetes-deaths-lowest-levels-years-early-cdc-figures/ XX Big news for the Eversense CGM – they have their first pump partner. Sequel Med Tech says the twist pump will integrate with Senseonics Eversense 365 continuous glucose monitor (CGM). This collaboration would make twiist the first AID system compatible with Eversense 365, the world's first and only one-year CGM. Sequel and Senseonics say they have already started their work to integrate the latest-generation, 365-day implantable sensor with twiist. They expect to make the integrated offering available in the third quarter of this year. This marks the second CGM integration for Sequel, which partnered with Abbott and its FreeStyle Libre platform earlier this year. This week we also got a peek at the packaging and delivery of the twist as the first people posted about wearing it. We'll follow up and learn more about this newest insulin pump in the us. Senseonics, meanwhile, brought the first year-long CGM to market last year, launching Eversense 365 with its global distribution partner, Ascensia Diabetes Care, in October 2024. The system also received clearance as an integrated CGM (iCGM) system, meaning it can work with compatible medical devices. Those include insulin pumps as part of automated insulin delivery systems. https://www.drugdeliverybusiness.com/sequel-senseonics-integrate-cgm-insulin-pump/ XX Medtronic has announced the U.S. Food and Drug Administration (FDA) approval for the Simplera Sync sensor for use with the MiniMed 780G system. With this approval, the MiniMed 780G system now offers more flexibility for users of the company's most advanced insulin delivery system featuring Meal Detection technology with both the Guardian 4 sensor and Simplera Sync sensor. The Simplera Sync is a disposable, all-in-one sensor that requires no fingersticks with SmartGuard or overtape and features a simple, two-step insertion process. It is the company's newest addition to its CGM portfolio, which expands options and provides greater flexibility for users. The MiniMed 780G system's adaptive algorithm automatically anticipates, adjusts, and corrects glucose levels every 5 minutes, 24/7 – working around the clock so users can focus on what matters. It's the only system featuring Meal Detection technology, which detects rising sugar levels and delivers more insulin as needed to help users keep glucose levels in range more often – even when users occasionally forget to dose insulin for snacks or meals or underestimate their carbs. The system uses a “treat to target” approach and flexible glucose targets as low as 100 mg/dL, which, combined with its adaptive algorithm allows it to more closely mirror the glucose levels of someone not living with diabetes. Real-world data of the system shows global users consistently achieve time in range above international targets of 70% when using optimal settings (active insulin time of two hours and 100 mg/dL target glucose). It is also the only system that works with the world's only infusion set that lasts up to 7 days so that users only have to change their infusion set once per week and can experience 96% fewer injections compared to multiple daily injections. “We're committed to driving innovation that makes life easier for those living with diabetes so they can forget about their diabetes as much as possible throughout the day,” said Que Dallara, EVP and president of Medtronic Diabetes. “Our MiniMed 780G system delivers advanced diabetes technology for so many around the world, and we're excited to continue evolving this experience with expanded CGM options —including our Simplera Sync sensor, which we look forward to bringing to people living with diabetes in the U.S.” A limited launch of the Simplera Sync sensor will begin in the U.S. in the fall of 2025. Today, the MiniMed 780G system can be used with the Guardian 4 sensor. Like this:https://med-techinsights.com/2025/04/29/simplera-sync-sensor-for-minimed-780g-now-fda-approved/ XX Front office changes at Insulet.. The former head of Johnson & Johnson's worldwide medtech business, Ashley McEvoy will take over as president and CEO from Jim Hollingshead, who has led Insulet since 2022. In its announcement of the leadership change, Insulet said that Hollingshead and the company mutually agreed to part ways, effective immediately. McEvoy served as worldwide medtech chairman at J&J from 2018 until her departure in late 2023, the culmination of nearly 30 years at the company and several executive roles—including president of its Ethicon division and group chairman of vision and diabetes care. Since then, she has also served as a board member at Procter & Gamble. https://www.fiercebiotech.com/medtech/insulet-taps-former-jj-medtech-head-ashley-mcevoy-be-ceo XX New free mobile game launched this week to make type 1 diabetes onboarding faster easier and less overwhelming. It's called Level One.. created by Level Ex (Powered by Relevate Health), the studio behind award-winning medical games for medical professionals. Level Ex CEO Sam Glassenberg created the game after a – quote - brutal onboarding experience when his daughter was diagnosed five years ago He says It took a year to understand how to manage this disease. So we fixed it. We built a game that can train your brain to do it in a matter of hours." The game is launching in partnership with leading diabetes organizations Beyond Type 1 and Breakthrough T1D Play, who are integrating Level One into their outreach and educational campaigns to support newly diagnosed families worldwide. Download Level One on the App Store: https://apps.apple.com/us/app/level-one-a-diabetes-game/id6739605694 Learn more: https://playlevelone.com https://www.prnewswire.com/news-releases/level-ex-launches-level-one-a-free-mobile-game-to-redefine-type-1-diabetes-onboarding-302440929.html XX Collagen is widely recognized for its role in maintaining healthy skin, but its importance extends far beyond that. As the most abundant protein in the human body, collagen provides essential structure and support to nearly all tissues and organs. Now, researchers at Carnegie Mellon's Feinberg Lab have made a major breakthrough using their novel Freeform Reversible Embedding of Suspended Hydrogels (FRESH) 3D bioprinting technique. This method enables the precise printing of soft, living cells and tissues. Leveraging this technology, the team successfully created the first-ever microphysiologic system, also known as a tissue model, constructed entirely from collagen. This advancement opens new possibilities for studying disease and engineering tissue therapies, including potential treatments for conditions like Type 1 diabetes. Traditionally, small-scale models of human tissue, referred to as microfluidics, organ-on-chip devices, or microphysiologic systems, have been fabricated using synthetic materials such as silicone rubber or plastics. These materials were necessary due to limitations in earlier manufacturing techniques. However, because they are not biologically native, they fail to fully replicate natural tissue environments, restricting their effectiveness in biomedical research and therapeutic development. “Now, we can build microfluidic systems in the Petri dish entirely out of collagen, cells, and other proteins, with unprecedented structural resolution and fidelity,” explained Adam Feinberg, a professor of biomedical engineering and materials science & engineering at Carnegie Mellon University. “Most importantly, these models are fully biologic, which means cells function better.” Building Complex Tissues with FRESH Bioprinting In new research published in Science Advances, the group demonstrates the use of this FRESH bioprinting advancement, building more complex vascularized tissues out of fully biologic materials, to create a pancreatic-like tissue that could potentially be used in the future to treat Type 1 diabetes. This advancement in FRESH bioprinting builds on the team's earlier work published in Science, by improving the resolution and quality to create fluidic channels that are like blood vessels down to about 100-micron diameter. “There were several key technical developments to the FRESH printing technology that enabled this work,” described Daniel Shiwarski, assistant professor of bioengineering at the University of Pittsburgh and prior postdoctoral fellow in the Feinberg lab. “By implementing a single-step bioprinting fabrication process, we manufactured collagen-based perfusable CHIPS in a wide range of designs that exceed the resolution and printed fidelity of any other known bioprinting approach to date. Further, when combined with multi-material 3D bioprinting of ECM proteins, growth factors, and cell-laden bioinks and integration into a custom bioreactor platform, we were able to create a centimeter-scale pancreatic-like tissue construct capable of producing glucose-stimulated insulin release exceeding current organoid based approaches.” https://scitechdaily.com/scientists-bioprint-living-tissues-that-could-revolutionize-diabetes-treatment/ XX Another study showing the blood sugar benefit of walking after a meal. Skeletal muscle plays a central role in glucose uptake. Exercise stimulates glucose transport into muscle cells through insulin-independent pathways, notably through the action of glucose transporter type 4 (GLUT-4), which is responsible for transporting glucose from blood to skeletal muscles.4 This means that even without a robust insulin response, physical activity can facilitate glucose clearance from the bloodstream. These effects also occur without requiring high-intensity exercise, making postprandial walking accessible to a broad range of individuals, including those with limited exercise tolerance. multiple studies show that starting activity within 30 minutes after a meal is optimal. https://www.news-medical.net/health/Walking-After-Meals-Small-Habit-Big-Metabolic-Gains.aspx XX Dexcom brings back Dexcom U for a 4th years. This is a name, image and license program for college athletes with diabetes and includes a nationwide open call for passionate and inspiring college athletes to join its roster. Now through May 23, athletes, coaches, friends and family members can nominate candidates through an online submission. Those selected, along with the eight returning athletes from last year, will be invited to attend the Dexcom U Signing Day Camp this summer, hosted by Dexcom Warrior and Baltimore Ravens tight end Mark Andrews. https://www.hmenews.com/article/dexcom-u-returns-for-fourth-season
Tune in to this episode of the Security Token Show where this week Herwig Konings and Kyle Sonlin cover the industry leading headlines and market movements, including RWA DeFi vaults, venture funding coming back, and more RWA news! Company of the Week - Herwig: Particula Company of the Week - Kyle: KfW The Market Movements 1. Circle Rejects Ripple's $5B Acquisition Offer, New $20B Offer Reported: https://cointelegraph.com/news/ripple-circle-bid-rejected-bloomberg https://x.com/Cointelegraph/status/1918261724224098651 2. BlackRock Files to Tokenize $150B Treasury Trust Fund with BNY Mellon: https://www.coindesk.com/markets/2025/04/30/sec-filing-shows-blackrock-preparing-150-billion-tokenized-treasury-trust-offering 3. Particula Closes $5.5M Raise and Moves to USA: https://particula.io/particula-raises-5m-funding-round/ 4. Dinari Raises $12.7M Series A led by Hack VC and Blockchange Ventures: https://dinari.com/blog/12m-series-a-equities-onchain 5. Tether Attestation Report: More than 7.7 Tons of Gold Backing XAUT: https://crypto.news/tether-holds-more-than-7-7-tons-of-gold-backing-its-xaut-token/ 6. MetaWealth Now Registered in Lithuania as VASP: https://thepaypers.com/online-mobile-banking/metawealth-gains-a-virtual-asset-service-provider-licence-in-lithuania--1273351 7. Sony's Soneium and Plume Partner for Onchain Staking and Yield Opportunities: https://www.techinasia.com/news/sonys-blockchain-plume-partner-tokenized-yields The Token Debrief 1. Calastone Announces Fireblocks as Infrastructure Partner for Fund Tokenization: https://financefeeds.com/calastone-partners-with-fireblocks-to-launch-fund-tokenization-platform/ 2. Centrifuge Introduces RWA Launchpad: https://centrifuge.mirror.xyz/Ujcfp4flrFUGxLUEXiDlwZH1ZCfLmh4HMdXI1CUP-XQ 3. ERC3643 Association Announces Interoperable DvP Proof of Concept: https://www.linkedin.com/posts/erc3643_erc3643-activity-7323571899043659776-aPCX 4. Goldman Sachs to Expand Crypto Trading and Explore Crypto Lending & Asset Tokenization: https://www.coinspeaker.com/goldman-sachs-eyes-expansion-in-crypto-trading/ 5. Nairobi Securities Exchange (NSE) and DeFi Technologies Create Kenya Digital Exchange: https://coingeek.com/kenya-prepares-tokenizing-rwas-on-homegrown-exchange/ 6. Securitize and Gauntlet Use Morpho to Launch Vault for Apollo's ACRED: https://securitize.io/learn/press/securitize-and-gauntlet-launch-levered-rwa-strategy-on-apollo-diversified-credit-securitize-fund 7. Libre to Bring Institutions to TON with $500M Telegram Bond Fund ($TBF): https://www.librecapital.com/insights/libre-and-ton-foundation-launch-500m-telegram-bond-fund-tbf-on-ton-blockchain 8. Hilbert Group Announces Tokenized Bitcoin Yield Offering on Rebranded Syntetika Platform: https://finance.yahoo.com/news/hilbert-group-announces-launch-tokenized-082000090.html 9. KfW Moves from Issuer to Investor, Invests €10M in Berlin Hyp's €100M Covered Bond: https://www.kfw.de/About-KfW/Newsroom/Latest-News/Pressemitteilungen-Details_848192.html 10. Wormhole to Provide Interoperability for Mercado Bitcoin's $200M Pipeline and Invests in Offering: https://www.tronweekly.com/mercado-bitcoin-partners-with-wormhole/ 11. MultiBank to Tokenize $3B of MAG's UAE Real Estate on Mavryk: https://cointelegraph.com/news/multibank-mag-mavryk-3b-rwa-tokenization-launch 12. Liquid Noble Adds More Utility to $LGAU Tokenized Gold: https://coingeek.com/liquid-noble-revamps-for-improved-tokenized-bullion-trading/ 13. Solana Policy Institute, Superstate, and Orca Submit Proposal for Project Open: US Equities on Public Blockchains https://www.linkedin.com/posts/solana-policy-institute_project-open-wireframe-blueprint-4282025-activity-7323417793951895553-e_W0 14. Pakistan Approves First Tokenized Gold Solution under Fasset's Sandbox License: https://www.urdupoint.com/en/technology/fasset-secures-sandbox-license-to-launch-paki-1971443.html 15. Argentinian Regulator Presents Tokenization Framework: https://invezz.com/news/2025/04/27/latam-crypto-news-itau-to-invest-210m-in-bitcoin-and-argentinas-cnv-to-present-new-tokenization-regime/ 16. World Federation of Exchanges Releases Report on CBDC Impact on Tokenization: https://www.ledgerinsights.com/world-federation-of-exchanges-explore-cbdc-for-tokenization/ 17. Deloitte Predicts 25% of Cross-Border Payments Delivered Onchain by 2030, $50B in Savings: https://fintechmagazine.com/articles/deloitte-tokenised-networks-to-reshape-global-payments = Stay in touch via our Social Media = Kyle: https://www.linkedin.com/in/kylesonlin / Herwig: https://www.linkedin.com/in/herwigkonings/ Opinion articles, interviews, and more: https://medium.com/security-token-group Find the video edition of this episode on our Youtube Channel: https://www.youtube.com/@stmtvofficial STM Predicts $30-50T in RWAs by 2030: https://docsend.com/view/7jx2nsjq6dsun2b9 More STM.co Reports: https://reports.stm.co/ Join the RWA Foundation and Read the Whitepaper: RWAF.xyz ⏰ TABLE OF CONTENTS ⏰ 0:00 Introduction 0:16 Welcome 1:05 Market Movements 14:14 RWA Foundation Update 15:04 Token Debrief 26:04 Companies of The Week
Today's blockchain and cryptocurrency news Bitcoin is down slightly at $94,937 Eth is up 2% at $1,806 XRP, is up 3% at $2.23 The SEC ends investigation into PYUSD. Trump Media & Technology Group explores utility for TRUMP BlackRock files to offer tokenized shares. Libre plans to tokenize 500 million dollars in Telegram-issued bonds Bunq launches crypto trading in 6 countries. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this jam-packed episode, Dr. Jeremy Pettus and Dr. Steve Edelman team up with special guest Dr. David Ahn to break down the latest and greatest in diabetes technology for 2025. From extended-wear CGMs to fully automatic hybrid closed-loop pumps and dual-hormonal systems, this episode is your complete guide to what's available now and what's coming soon. Whether you're on MDI, using a pump, or considering a tech upgrade, this conversation will help you navigate the expanding world of devices—and find the right setup for you.Key Topics:Extended-Wear CGMs: The Dexcom G7 now lasts over 15 days—and the Eversense implantable sensor lasts a full year.Over-the-Counter CGMs: Learn about Dexcom Stelo and Abbott Lingo, designed for people without diabetes.New Pump Launches: Including Tandem Mobi, Beta Bionics iLet, Sequel Twist, and Medtronic's MiniMed™ 780G with Simplera Sync sensor.Medtronic Simplera Sync: What to know about its U.S. launch, wear time, and integration with the 780G system.Dual-Hormone Systems: Explore how glucagon is being used alongside insulin to prevent lows and simplify diabetes management.Ketone Monitoring: Continuous ketone sensors are on the horizon, and they could change how we detect and prevent DKA.Improved App Integration: Discover updates in CGM and pump interfaces for iPhone and Android, including Libre 3+ and universal app platforms.Customizing Your Combo: Why matching the right CGM with the right pump (or sticking with MDI) is more doable—and more important—than ever. ★ Support this podcast ★
¡Atención, atención! ¡Paren las orejas, que hoy celebramos a los reyes del hogar! ¡Sí, esos que brincan, gritan, lloran y comen como si el refri fuera bufet libre! ¡Feliz Día del Niño, raza!See omnystudio.com/listener for privacy information.
Un jeune orque orphelin, piégé dans une lagune depuis plus d'un mois au large de la côte de la Colombie-Britannique, est enfin libre.Traduction :An orphan orca calf that has been trapped in a lagoon for more than a month off the coast of British Columbia is finally free. Hosted on Acast. See acast.com/privacy for more information.