POPULARITY
5 episodes with hydrogen sulfide
5 episodes with hydrogen sulfide
3 episodes with hydrogen sulfide
4 episodes with hydrogen sulfide
2 episodes with hydrogen sulfide
2 episodes with hydrogen sulfide
2 episodes with hydrogen sulfide
2 episodes with hydrogen sulfide
2 episodes with hydrogen sulfide
In this encore episode, we go through the pathophysiology of hydrogen sulfide (H₂S)-dominant small intestinal bacterial overgrowth (SIBO), focusing on its role in intestinal motility disruption, microbial dysbiosis, and epithelial barrier dysfunction. We detail the interplay between the enteric nervous system (ENS), interstitial cells of Cajal (ICCs), and migrating motor complex (MMC) in regulating small intestinal transit and how excess H₂S modulates smooth muscle activity, inflammatory signaling, and gastrointestinal transit time. Lastly, we detail symptoms and related SIBO subtypes.Topics:1. Introduction to Hydrogen Sulfide Dominant SIBO - Overview of hydrogen sulfide (H₂S) SIBO - Sulfate as an electron acceptor - H₂S production, sulfur-containing amino acids - Physiological roles of H₂S vs. in excess 2. Hydrogen Sulfide and Gastrointestinal Motility - Impact on transit time - Association with IBS-like symptoms, diarrhea 3. Intestinal Motility and Regulation - Role of the ENS, ICCs, smooth muscle cells, and neurotransmitters in motility 4. The Enteric Nervous System (ENS) and Gut Motility - ENS as the "second brain" and its control over digestion - Myenteric and submucosal plexuses: regulation of peristalsis, secretion, blood flow - Gut-brain axis involvement via vagus nerve signaling - ICCs as pacemaker cells generating slow-wave electrical activity - MMC's role in clearing debris and bacteria 5. Dysregulated Motility and SIBO Development 6. Overlapping Symptoms Across SIBO Subtypes - Shared symptoms - Hydrogen and H₂S-dominant SIBO vs. IMO 7. Gastric Acid and Its Role - HCl secretion by parietal cells and its role in digestion and microbial defense - Hypochlorhydria and bacterial overgrowth 8. Conclusion - Root cause approach.Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
Think you might have IBS or Small Intestine Bacterial Overgrowth—but diet changes aren't helping?There's a lesser-known type of SIBO that's often missed: Hydrogen Sulfide SIBO.Unlike the hydrogen or methane types, hydrogen sulfide is a neurotoxin that can trigger strange symptoms—like nerve pain, bladder irritation, or even fibromyalgia-like pain. It also plays a major role in the gut-skin connection.But it often doesn't show up on standard SIBO tests, making it hard to diagnose.I'm joined by Dr. Allison Siebecker (renown SIBO expert) to dive into this complex gut issue that can also play a role in messing up your skin (since SIBO is tied to rosacea, psoriasis, and histamine intolerance).⭐️Mentioned in This Episode:- Find Dr. Siebecker
In this encore episode, we detail the pathophysiology of intestinal methanogen overgrowth (IMO), hydrogen-dominant small intestinal bacterial overgrowth (H₂-SIBO), and hydrogen sulfide-dominant SIBO (H₂S-SIBO), discussing their mechanistic interactions and overlap. We discuss methanogenic archaea, as well hydrogen sulfide- and hydrogen-producing microbes and their contributions to altered gastrointestinal motility, epithelial barrier function, and neuromuscular signaling. We detail host endogenous defense mechanisms, including gastric acid secretion, pancreatic enzymatic activity, bile flow, intestinal motility, and more.Topics:1. Introduction- Overview of intestinal methanogen overgrowth (IMO), hydrogen sulfide-dominant SIBO, and hydrogen-dominant SIBO - Discussion of overlap 2. Intestinal Methanogen Overgrowth (IMO)- Characterized by an overabundance of methane-producing archaea - Methane and intestinal transit- Bloating, abdominal discomfort, constipation - Associated with irritable bowel syndrome with constipation (IBS-C) 3. Overlap Between IMO and SIBO Subtypes- Hydrogen as a substrate for methane and/or hydrogen sulfide production- Shared potential root causes 4. Small Intestinal Bacterial Overgrowth (SIBO) and Protective Mechanisms- The small intestine remains relatively free of bacteria due to protective mechanisms - Gastric acid secretion - Pancreatic enzymes and bile - Intestinal motility- Structural abnormalities 5. Hydrogen-Dominant SIBO - Increased hydrogen and intestinal transit- Potential symptoms, diarrhea, postprandial bloating - Different forms of SIBO can coexist 6. Hydrogen Sulfide-Dominant SIBO - H₂S and intestinal motility- H₂S and intestinal epithelial integrity- Symptoms, associations with IBS diarrhea 7. Host Defense Mechanisms Regulating Microbial Balance- Gastric acid secretion, pancreatic enzyme activity, bile flow, intestinal motility, and more 8. Gastric Acid and Its Role in Microbial Regulation- Parietal cells secrete hydrochloric acid (HCl) and intrinsic factor - Chief cells secrete pepsinogen, conversion into pepsin in acidic conditions - Gastric acid, digestion and antimicrobial defense 9. Hypochlorhydria - Low gastric acid impairs microbial defense- Reduced acidity disrupts digestion and downstream pancreatic enzyme and bile release 10. Pancreatic Enzymes and Their Role in Microbial Regulation- Pancreatic enzymes, digestion, antimicrobial activity - Enzymes modify chyme to limit fermentable substrates that fuel microbial proliferation 11. Intestinal Motility - Coordinated contractions propel food, microbes, and waste through the GI tract - The enteric nervous system (ENS) and gut motility- The myenteric plexus controls peristalsis, while the submucosal plexus regulates secretion and absorption 12. Conclusion- Intestinal methanogen overgrowth (IMO), hydrogen-dominant SIBO, and hydrogen sulfide-dominant SIBO - Overlap in symptoms and microbial interactions - Host defense mechanisms, including gastric acid, pancreatic enzymes, and motility - Intestinal motility and ENS function in microbial homeostasis - Hydrogen sulfide as a gasotransmitterGet Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
In this episode, we detail the pathophysiology of intestinal methanogen overgrowth (IMO), hydrogen-dominant small intestinal bacterial overgrowth (H₂-SIBO), and hydrogen sulfide-dominant SIBO (H₂S-SIBO), discussing their mechanistic interactions and overlap. We discuss methanogenic archaea, as well hydrogen sulfide- and hydrogen-producing microbes and their contributions to altered gastrointestinal motility, epithelial barrier function, and neuromuscular signaling. We detail host endogenous defense mechanisms, including gastric acid secretion, pancreatic enzymatic activity, bile flow, intestinal motility, and more.Topics:1. Introduction- Overview of intestinal methanogen overgrowth (IMO), hydrogen sulfide-dominant SIBO, and hydrogen-dominant SIBO - Discussion of overlap 2. Intestinal Methanogen Overgrowth (IMO)- Characterized by an overabundance of methane-producing archaea - Methane and intestinal transit- Bloating, abdominal discomfort, constipation - Associated with irritable bowel syndrome with constipation (IBS-C) 3. Overlap Between IMO and SIBO Subtypes- Hydrogen as a substrate for methane and/or hydrogen sulfide production- Shared potential root causes 4. Small Intestinal Bacterial Overgrowth (SIBO) and Protective Mechanisms- The small intestine remains relatively free of bacteria due to protective mechanisms - Gastric acid secretion - Pancreatic enzymes and bile - Intestinal motility- Structural abnormalities 5. Hydrogen-Dominant SIBO - Increased hydrogen and intestinal transit- Potential symptoms, diarrhea, postprandial bloating - Different forms of SIBO can coexist 6. Hydrogen Sulfide-Dominant SIBO - H₂S and intestinal motility- H₂S and intestinal epithelial integrity- Symptoms, associations with IBS diarrhea 7. Host Defense Mechanisms Regulating Microbial Balance- Gastric acid secretion, pancreatic enzyme activity, bile flow, intestinal motility, and more 8. Gastric Acid and Its Role in Microbial Regulation- Parietal cells secrete hydrochloric acid (HCl) and intrinsic factor - Chief cells secrete pepsinogen, conversion into pepsin in acidic conditions - Gastric acid, digestion and antimicrobial defense 9. Hypochlorhydria - Low gastric acid impairs microbial defense- Reduced acidity disrupts digestion and downstream pancreatic enzyme and bile release 10. Pancreatic Enzymes and Their Role in Microbial Regulation- Pancreatic enzymes, digestion, antimicrobial activity - Enzymes modify chyme to limit fermentable substrates that fuel microbial proliferation 11. Intestinal Motility - Coordinated contractions propel food, microbes, and waste through the GI tract - The enteric nervous system (ENS) and gut motility- The myenteric plexus controls peristalsis, while the submucosal plexus regulates secretion and absorption 12. Conclusion- Intestinal methanogen overgrowth (IMO), hydrogen-dominant SIBO, and hydrogen sulfide-dominant SIBO - Overlap in symptoms and microbial interactions - Host defense mechanisms, including gastric acid, pancreatic enzymes, and motility - Intestinal motility and ENS function in microbial homeostasis - Hydrogen sulfide as a gasotransmitterThank you to our episode sponsors:1. Shop Fresh Press Farms'Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection here. 2. Shop CYLN's full skincare line here.Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
In this episode, we go through the pathophysiology of hydrogen sulfide (H₂S)-dominant small intestinal bacterial overgrowth (SIBO), focusing on its role in intestinal motility disruption, microbial dysbiosis, and epithelial barrier dysfunction. We detail the interplay between the enteric nervous system (ENS), interstitial cells of Cajal (ICCs), and migrating motor complex (MMC) in regulating small intestinal transit and how excess H₂S modulates smooth muscle activity, inflammatory signaling, and gastrointestinal transit time. Lastly, we detail symptoms and related SIBO subtypes.Topics:1. Introduction to Hydrogen Sulfide Dominant SIBO - Overview of hydrogen sulfide (H₂S) SIBO - Sulfate as an electron acceptor - H₂S production, sulfur-containing amino acids - Physiological roles of H₂S vs. in excess 2. Hydrogen Sulfide and Gastrointestinal Motility - Impact on transit time - Association with IBS-like symptoms, diarrhea 3. Intestinal Motility and Regulation - Role of the ENS, ICCs, smooth muscle cells, and neurotransmitters in motility 4. The Enteric Nervous System (ENS) and Gut Motility - ENS as the "second brain" and its control over digestion - Myenteric and submucosal plexuses: regulation of peristalsis, secretion, blood flow - Gut-brain axis involvement via vagus nerve signaling - ICCs as pacemaker cells generating slow-wave electrical activity - MMC's role in clearing debris and bacteria 5. Dysregulated Motility and SIBO Development 6. Overlapping Symptoms Across SIBO Subtypes - Shared symptoms - Hydrogen and H₂S-dominant SIBO vs. IMO 7. Gastric Acid and Its Role - HCl secretion by parietal cells and its role in digestion and microbial defense - Hypochlorhydria and bacterial overgrowth 8. Conclusion - Root cause approach.Thank you to our episode sponsors:1. Check out Ulyana Organics'Tallow Wild Yam Cream and Healing Facial Oil, and use code CHLOE10 10% off your order.2. Shop the Scalp Cleanser and Scalp Essence from T Stem Care. Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
Send us a Text Message.In this episode of the Gut Health Dialogues, host Alyssa Simpson shares an inspiring client consultation whose remarkable journey to improved gut health will resonate with anyone struggling with identifying their type of SIBO.Beth discovered Alyssa through the Monash app, seeking help after years of restrictive eating due to following a low FODMAP diet. Despite her efforts, she continued to experience debilitating symptoms. Beth's journey underscores the importance of identifying the root cause of gut issues and finding the right treatment. Her transformation offers hope and practical insights for anyone facing similar challenges.Why You Should Listen:Discover how specific diets can address unique gut health issues.Learn the importance of proper diagnosis and personalized treatment.Get inspired by Beth's success and find hope for your own journey.Listen now to gain valuable tips and strategies for managing SIBO and enhancing your overall gut health.Grab your freebies here:Start your Low FODMAP diet with easy, family-friendly meals that won't cause complaints: First Week on FODMAP Meal Plan.Equip yourself with essential tools, including food apps, supplement suggestions, and more: IBS Resource Guide.Explore deeper strategies to address the root causes of your digestive issues: Functional Nutrition Blog Post.Connect with Alyssa here:FB: https://www.facebook.com/nutritionresolution/ Pinterest: https://www.pinterest.com/alyssasimpsondietitian/ IG: https://www.instagram.com/nutritionresolution LinkedIn: https://www.linkedin.com/in/alyssasimpsonrdn/ Book a free consultation to discuss personalized gut health solutions: 15-Minute Scheduling Link
Addressing adverse food reactions goes way beyond simply cutting out the culprits, so I'm thrilled to have Dr. Tom Fabian join us again on New Frontiers to highlight the interventions that will move the needle for our patients. We explore the mechanisms through which specific strains can either exacerbate or alleviate both immune-mediated and non-immune-mediated food reactions, and discuss the fascinating connection between circadian rhythms of mast cells and intestinal permeability, feeding times and increased susceptibility to food reactivity. We look at why some patients may be more sensitive to symptoms and how histamine-producing microbes may lead to visceral hypersensitivity. But we also talk strategy, with one pearl after another, such as the potential of Lactobacillus reuteri in attenuating immune-mediated food reactions, the role of butyrate and indole in stabilizing mast cells, and using specific polyphenols to calm the immune system and promote a health microbiome. For any practitioner or health-savvy individual grappling with these issues, this is an episode you won't want to miss. ~DrKF Head over to https://www.drkarafitzgerald.com/fxmed-podcast/ for the transcript, a COMPLETE LIST OF SHOW NOTES and all the FxMed resources. GUEST INFORMATION Thomas Fabian, PhD, CNTP https://tinyurl.com/sd845cye Dr. Fabian serves as a translational science consultant and science advisor with Diagnostic Solutions Laboratory and is a leading expert on the role of the microbiome in health, immune function, chronic disease, and aging. THANK YOU TO OUR SPONSOR Diagnostic Solutions Laboratory https://bit.ly/2IEhVrS *SPECIAL OFFER FOR FxMED LISTENERS* Diagnostic Solutions Laboratory invites you to download the GI-MAP Interpretive Guide at https://tinyurl.com/5ekvrchr. This helpful guide can help you better understand and interpret test results for your patients. Download and follow along with the episode. SHOW NOTES Understanding food allergy through neuroimmune interactions in the gastrointestinal tract https://tinyurl.com/2kstjrzp The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes https://tinyurl.com/5n7ymaj4 DSL Webinar: Neuroinflammation and the Gut-Brain Connection https://tinyurl.com/ykeeehnk Mechanisms Underlying Food-Triggered Symptoms in Disorders of Gut-Brain Interactions https://tinyurl.com/yhb5ddyc FxMED RESOURCES Gut Healing in Aging & Disease: Emerging Roles of the Microbiome and Diet in Intestinal Barrier Regeneration with Tom Fabian, PhD, CNTP https://tinyurl.com/h3rtumbs Hydrogen Sulfide in Health, Disease & Longevity with Dr. Tom Fabian https://tinyurl.com/25fmk83n Latest Insights into the Role of the Gut Microbiome in Healthy Aging with Dr. Tom Fabian https://tinyurl.com/bdz5u7vz CONNECT WITH DrKF Facebook: https://www.facebook.com/DrKaraFitzgerald/ YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Bio Age Lab Test: https://tinyurl.com/b7bjmfj9 Bio Age Self Assessment Quiz: https://tinyurl.com/4z8f7ucc
The Perfect Stool Understanding and Healing the Gut Microbiome
Explore the often overlooked diagnosis of hydrogen sulfide SIBO (small intestine bacterial overgrowth) and its diverse array of symptoms, including food intolerances, inflammation, diarrhea and abdominal pain, shedding light on its association with conditions like IBD, colorectal cancer and Parkinson's Disease. Gain invaluable insights into testing, treatment and dietary adjustments crucial for managing hydrogen sulfide SIBO and reclaiming gut health. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, Twitter, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up a free 30-minute Gut Healing Breakthrough Session. Show Notes
Unlock the hidden truths behind the dualistic nature of Hydrogen Sulfide as our expert guests, Dr. Nirala Jacobi and Dr. Kathleen Janel joins us in our latest episode "High Dose Sulfur for IBS". This episode is a deep dive into the dichotomy that exists within our gut, exploring how this compound can simultaneously pose as a health aid and a health threat. Come join us as we learn about its role in various illnesses like Small Intestinal Bacterial Overgrowth (SIBO), Irritable Bowel Syndrome (IBS), and Inflammatory Bowel Disease (IBD) and understand how an imbalance of this compound leads to these disorders. We will also shed light on how sulfur, commonly seen as a villain in the narrative of gut disorders, can be used as a superhero in the treatment of these conditions. Dr. Kathleen Janel, who has been a pioneer in this revolutionizing treatment approach, will share her insights and personal success stories utilizing high doses of sulfur for more than two decades. Don't miss this intriguing transformational health journey as we challenge the conventional belief systems about sulfur and its role in gut health.
Arbor Quist, PhD is an environmental epidemiologist interested in community-driven research that addresses climate and environmental injustice. Quist recently completed her PhD in epidemiology at the University of North Carolina at Chapel Hill. Her dissertation examined how hurricane flooding and industrial swine operations, separately and jointly, affect acute gastrointestinal illness. Her research has focused on the ways in which climate change-related disasters exacerbate health disparities. Quist has also worked with communities after hurricane flooding to examine well water contamination and mold concerns in North Carolina to promote community resilience and preparedness. She has also worked on projects examining the neurobehavioral effects of oil spills. Currently, Quist is examining the health effects of oil drilling in South Los Angeles and metal mixture exposure patterns in residents near oil wells.Learn more about this episode and others at pphs.usc.edu/podcastStay in the loop - subscribe to the Preventive Dose newsletter for monthly news straight to your inbox.Follow us on social - find us at @uscpphs Instagram TikTok Facebook LinkedIn X YouTube
#291 Dr. Goldenberg is passionate about how we evaluate and utilize evidence. He is an active researcher with numerous publications in high-impact scientific journals such as JAMA and the BMJ and is an Associate Research Investigator at the Helfgott Research Institute. He is faculty for the Academy of Integrative Health and Medicine and the Helfgott Research Institute where he teaches critical evaluation of the medical literature and advanced evidence synthesis. His love for teaching integrative evidence-based medicine led him to found the DrJourncalClub website and Podcast. He received his Doctorate in Naturopathic Medicine from Bastyr University and his Bachelor's in Molecular Biology with honors from the University of Pennsylvania. He is a past President of the Gastroenterology Association of Naturopathic Physicians and a Fellow of the American Board of Naturopathic Gastroenterology. His clinical focus is on integrative approaches to gastroenterology conditions with a special focus on small intestinal bacterial overgrowth. He sees patients virtually at the Goldenberg GI Center. His interest in evidence has taken him from clinic to courtroom, recently co-founding three businesses focusing on brain injury litigation and forensic epidemiology. In this episode we cover What is hydrogen sulfide and what is its function in the body When does hydrogen sulfide become a problem and what may one experience if they have H2S overgrowth Joshua's insight from his current research on Hydrogen Sulphide SIBO How is Joshua currently testing for it? He sheds light on the new at-home handheld devices for SIBO testing Treatment strategies for Hydrogen sulphide SIBO And so much more
Welcome to another episode of The Synthesis of Wellness Podcast! This episode covers almost everything you would want to know about different microbial overgrowths that can occur within the small intestines. Topics: 1. Introduction - Overview of different diagnoses related to gut dysbiosis - Types of intestinal microbial overgrowth: hydrogen dominant SIBO, hydrogen sulfide SIBO, IMO (intestinal methanogen overgrowth), SIFO (Small Intestinal Fungal Overgrowth), LIBO (Large Intestinal Bacterial Overgrowth) - Importance of the small intestine in nutrient absorption - Protective mechanisms against overgrowth: gastric acid secretion and intestinal motility 2. Prevalence and Risk Factors - Prevalence of SIBO among individuals with Irritable bowel syndrome, intestinal motility disorders, and chronic pancreatitis - Factors increasing SIBO prevalence: age, lower levels of stomach acid, slower gut motility - Female predominance in SIBO cases - Prevalence of undiagnosed SIBO and SIFO in the population 3. Symptoms and Malabsorption Issues - Common signs of small intestinal overgrowth: bloating, excessive gas, diarrhea, constipation, abdominal pain, and cramping - Nutrient malabsorption: fat-soluble vitamins (A, D, E, K), essential minerals (iron, calcium, magnesium), and B vitamins (B12, B1, B3) 4. Testing - Introduction to breath tests and stool tests - Trio Smart Breath Test for small intestinal overgrowth, assessing hydrogen, methane, and hydrogen sulfide levels - Unique testing options for SIFO using aspiration of small bowel fluids and urinary organic acids 5. Treatment Strategies for SIBO - Diet: Low FODMAP Diet and its impact on bacteria - Antimicrobial therapy using natural agents: Oregano oil, berberine, garlic, grapefruit seed extract - Probiotics for balancing gut bacteria - Prokinetics to improve gut motility 6. Treatment Strategies for IMO - Similarities with SIBO treatments - Elemental diet as a potential treatment - Reintroduction and Prevention Protocol - Use of intermittent fasting to stimulate the migrating motor complex 7. Treatment Strategies for SIFO - Addressing slow gut motility with prokinetics - Use of antifungals like fluconazole or herbal antifungals: artemisinin, oregano, garlic, olive leaf extract - Probiotic S. boulardii for reducing fungal colonization 8. Conclusion - Recap of the different small intestinal overgrowths: SIBO, IMO, & SIFO - Importance of identifying the specific type(s) for effective treatment - Understanding the symptoms, risk factors, and testing options for a personalized approach to wellness. Thanks for tuning in! If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram @synthesisofwellness, or use the link: https://www.instagram.com/synthesisofwellness/ Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, “Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome.” Hutchinson-Gilford progeria syndrome (HGPS) is a rare human disease characterized by accelerated biological aging. Current treatments are limited, and most patients die before 15 years of age. Hydrogen sulfide (H2S) is an important gaseous signaling molecule that is central to multiple cellular homeostasis mechanisms. Dysregulation of tissue H2S levels is thought to contribute to an aging phenotype in many tissues across animal models. Whether H2S is altered in HGPS is unknown. In a new study, researchers Stephen E. Wilkie, Diana E. Marcu, Roderick N. Carter, Nicholas M. Morton, Susana Gonzalo, and Colin Selman from the University of Glasgow, University of Edinburgh, Saint Louis University, and Karolinska Institute investigated hepatic H2S production capacity and transcript, protein and enzymatic activity of proteins that regulate hepatic H2S production and disposal in a mouse model of HGPS (G609G mice, mutated Lmna gene equivalent to a causative mutation in HGPS patients). “This study was designed and undertaken due to the lack of understanding in the mechanistic targets of known treatments against HGPS and considering the positive association between H2S and longevity in model organisms.” Here, the researchers employed the HGPS mouse model G609G to test the hypothesis that, in contrast to anti-aging increases in H2S production, the accelerated aging typical of progeroid mice is associated with reduced hepatic H2S production. G609G mice were maintained on either regular chow (RC) or high fat diet (HFD). HFD has been previously shown to significantly extend lifespan of G609G mice, and compared to wild type (WT) mice maintained on RC. RC-fed G609G mice had significantly reduced hepatic H2S production capacity relative to WT mice, with a compensatory elevation in mRNA transcripts associated with several H2S production enzymes, including cystathionine-γ-lyase (CSE). H2S levels and CSE protein were partially rescued in HFD fed G609G mice. The data acquired here confirmed some aspects of the relevance of H2S in HGPS but raises more questions about the specific mechanisms at play. “Regardless, the work presented here addresses an area of research that remains critically understudied and provides new evidence that the accelerated ageing phenotype observed in HGPS may be partially explained by a reduction in hepatic H2S levels.” DOI - https://doi.org/10.18632/aging.204835 Corresponding authors - Colin Selman - colin.selman@glasgow.ac.uk, and Stephen E. Wilkie - stephen.wilkie@ki.se Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204835 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, progeria, hydrogen sulfide, high-fat diet, ageing, lamin A About Aging-US: Launched in 2009, Aging publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at www.Aging-US.com and connect with us on social media. MEDIA@IMPACTJOURNALS.COM
In this episode Sheldon speaks with Master Hydrogen Sulfide Trainer Stan Smiley. In this conversation, Sheldon and Mr. Smiley speak about the hidden dangers on Hydrogen Sulfide (H2S), H2S training and detergent suicide. Don't miss this revealing episode.
Quizmasters Lee and Marc meet with Kyle Anne for a trivia quiz on topics including Biology, History, Greek Mythology, Television, Video Games, Sports, Movie Cameos and more! Round One BIOLOGY - Chardota, arthropoda and mollusca are all examples of which biological, taxonomic rank? CRUSTACEANS - Including claws, how many pairs of legs do crawfish typically have? GAME OF THRONES - "We do not sow" are the words of which major house of Westeros? GREEK MYTHOLOGY - In Greek mythology, who was the daughter of Zeus and Leto and the twin sister of Apollo, and was considered the goddess of wild animals, the hunt, vegetation and of chastity and childbirth? U.S. HISTORY - What U.S. president was known as the "Father of the Constitution"? 80's TELEVISION - On the original Magnum P.I., which famous actor and filmmaker played the role of Magnum's elusive benefactor? Round Two VIDEO GAMES - In Nintendo's Zelda franchise, what is the term for the sacred relic (and symbol of power, wisdom, and courage) that is also the official crest of the royal family of Hyrule? TECHNOLOGY - What is a loom mechanism for weaving small patterns and also a character in the Harry Potter series? BAD SMELLS - Due to a high amount of Hydrogen Sulfide in the atmosphere, which planet is believed to smell similar to rotten eggs? SPORTS - In what sport would you find a picador? HISTORICAL GARMENTS - When Ilhan Omar was sworn into congress, she wore what kind of head covering (marking the lifting of a 181 year-old ban prohibiting the wearing of any kind of headwear in the chamber)? SATURDAY NIGHT LIVE - One of the show's longest running cast members, which Saturday Night alum holds the record for delivering the line "Live, from New York, it's Saturday night" (approximately 75 times)? Rate My Question FRENCH WORDS - One of [Marc's] favourite words, "Portmanteau", has another meaning. What is it? CELEBRITIES - What stand-up comedian turned actor, whose film debut was in 1999, befriended an octogenarian homeless woman living in a laundromat, bringing her as his date to a number of his movies' premieres? Final Questions ETYMOLOGY - What modern technology word derives from the Czechoslovakian word for forced labor? BOARD GAMES - The basis for what two player strategy game by Milton Bradley was allegedly enjoyed by 18th Century Captain Cook so much that before becoming better known by its common name was originally known as "Captain's Mistress"? MOVIE CAMEOS - Which actor, while starring in a 1997 comedy film, made a cameo appearance in his own film as Fire Marshall Bill, a comedic character developed by the actor for a sketch comedy show? Upcoming LIVE Know Nonsense Trivia Challenges June 27th, 2023 - Ollie's Pub - 7:30 pm EST June 28th, 2023 - Point Ybel Brewing Co. - 7:30 pm EST June29th, 2023 - FathomsRestaurant & Bar - 6:30 pm EST You can find out more information about that and all of our live events online at KnowNonsenseTrivia.com All of the Know Nonsense events are free to play and you can win prizes after every round. Thank you Thanks to our supporters on Patreon. Thank you, Quizdaddies – Gil, Tim, Tommy, Adam, Brandon, Blake, Spencer, Rick G Thank you, Team Captains – Kristin & Fletcher, Aaron, Matthew, David Holbrook, Lydia, Skyler, Hayden Thank you, Proverbial Lightkeepers – Elyse, Kaitlynn, Frank, Trent, Nina, Justin, Katie, Ryan, Robb, Captain Nick, Grant, Ian, Tim Gomez, Rachael, Moo, Rikki, Nabeel, Jon Lewis, Adam, Lisa, Spencer, Hank, Justin P., Cooper, Sarah, Karly, Lucas, Mike K., Cole, Adam, Caitlyn H, Sam, Spencer, Stephen, Cameron, Clay, JB, Joshua, James, Paul, Marit, JV, Jesse, Nathan, Steve Thank you, Rumplesnailtskins – Mike J., Mike C., Efren, Steven, Kenya, Dallas, Issa, Allison, Kevin & Sara, Alex, Loren, MJ, HBomb, Aaron, Laurel, FoxenV, Sarah, Edsicalz, Megan, brandon, Chris, Alec, Sai, Tim, Andrea, Ian, Aunt Kiki, Clay, Littlestoflambs, Seth, Bill, Marc P., Holgast, Nora, Joe, Emily, Andrew H., Joe, Cara, Nathan, Joey, Brian K., Zoe, Kristy, Kinkalot If you'd like to support the podcast and gain access to bonus content, please visit http://theknowno.com and click "Support." Header photo by KoolShooters Special Guest: Kyle Anne.
In this episode, Sheldon tells you how to use the Instructor Development Course (IDC) to grow your business. He also introduces the Hydrogen Sulfide IDC class online in July with Stan Smiley as the instructor. Visit Primus.training for more details.
Toxicology Fellow Nik Matsler joins us again to discuss more gas poisonings. Do you know how to properly protect yourself from hydrogen sulfide in the prehospital setting? EMS providers- come learn how to recognize these patients and where you might find them and most importantly how to keep yourself safe. We'll also discuss nerve agents and how to recognize and treat these as well.
Safety Wars Live March 16, 2023 Jim discussed Hydrogen Sulfide, OSHA and EPA news, and the apology of Dr. Naomi Wolf. We really encourage people to get along and resolve conflicts whether it is in your workplace, in society or politically. If you or someone you know is contemplating suicide please seek help. For all of your consulting and training needs give us a call at 845-269-5772 or drop us an email at Jim@safetywars.com. WE NOW HAVE A LIVE SHOW EVERY Weekday AT 8 TO 9 PM EST ON SAFETYFM.COM WE ARE AVAILABLE ON YOUR FAVORITE PODCAST PLATFORM AS SAFETY WARS. #Jimpoesl #safetywars #safetyfm #jayallen #HOP #Humanandorganizationalperformanc #safety #osha #safetywarslive #jcptechnicalservices #safetytraining #mediabias #happyholidays #suicide #coldstress #smartgoals #disasterprep #forklifts #energypolicy #2023 #HappyNewYear #REspirators #supervisortraining #Firstaidcpraed #suddencardiacarrest #bills #bengals #sexualharrassment #scaffolding #scaffoldingcollapse #workplacedeath #constructionsafety #nuclearwar #nuclear #radiological #disasterresponseworker #poweroutage #earthquakes #Fire #war #nuclear #bullying #politicalassasination #OSS #CIA #SimpleSabotage #911calls #sabotage.
What is your approach to hydrogen sulfide SIBO? In this episode of the Love Your Gut Podcast, I talk about the three types of SIBO, testing for Hydrogen Sulfide SIBO, symptoms to look out for, and how Hydrogen Sulfide SIBO works. Tune in to hear more about the changes you could make to improve your symptoms, various diets and their effects on SIBO, and the importance of increasing variety in our diets. Topics Covered in This Episode:Why hydrogen sulfide is toxic to your mitochondria [0:02]What is SIBO? What is hydrogen sulfide SIBO (HSI)? [1:50]Testing for diagnosing hydrogen sulfide SIBO? [10:20]Common symptoms of IBS SIBO? [12:40]What can you do to help hydrogen sulfide symptoms? [18:38]What are polyphenols and how do they help?[23:42]Where is the sulfur coming from in the gut? [25:27]What we use with our clients that we find helpful [34:55]Recommendations:Trio Smart Test.Bimuno.XOS+ GOS Prebiotic.SunFiber, Thorne FiberMend.The Healthy Happy Gut Cookbook.Increase prebiotic fibre, polyphenols, and resistant starch to your diet.Decrease saturated fats and animal proteins.Increase variety in fibre and color.I would love to connect on Instagram or drheatherfinley.co
In geologic history, extinctions have occurred after high levels of atmospheric CO2, when oceans are stratified and archae were well fed and proliferated, producing hydrogen sulfide, a poison often called "swamp gas." Here Franz Oeste, Brian von Herzen and Paul Beckwith discuss the possibility that current conditions on earth are leading to such an extinction. They are not much worried, believing that the proliferation of phytoplankton will help cool the planet, and it is the heat that causes ocean stratification, which is the condition necessary for these other dire conditions to arise. For the video, audio podcast, transcript, and comments: https://tosavetheworld.ca/episode-539-is-swamp-gas-in-our-future
In this episode, Sheldon continues the conversation with Certified H2S Master Instructor, Stan Smiley. Stan gives stories of his time in oil and gas, emergency response, and case studies related to H2S exposure. If you are exposed to hydrogen sulfide, then this is a must listen episode for understanding this common hazard.
Happy New Year! It's 2023 and Sheldon starts the year off with a important interview with H2S Certified Master Trainer, Stan Smiley. Mr. Smiley is one of a rare group of safety educators that bear the distinction of excellence in this by being designated as a Hydrogen Sulfide (H2S) Master Instructor®, numbering less than 123 worldwide and of those, one of 41 currently certified. Primus Global Media will host a H2S Instructor Development Course this February 15-17, 2023. For more information: primus.training
Hydrogen sulfide gas produces the characteristic smell of rotten eggs, sewers, stockyards, and landfills. The petroleum industry produces thousands of tons of the stuff each year as a byproduct of the processes that remove sulfur from petroleum, natural gas, coal, and other products. The industry faces substantial fines for emitting hydrogen sulfide, but remediation is […]
In this New Frontiers in Functional Medicine® podcast, Dr. Tom Fabian delivers a well-justified challenge to our current thinking and a chance to build a more nuanced approach that will improve patient results around the topic of hydrogen sulfide, a compound that we have typically thought of as the “problem child” behind certain difficult SIBO cases. However, there is a LOT more to know about it, such as its ability to convert to potent antioxidant compounds, and its therapeutic roles in cardiovascular and metabolic disorders (diabetes and NAFLD), neurodegenerative disorders, and more. But how do we start to both broaden and nuance our approach to assessing hydrogen sulfide status? And what interventions can not only supply the substrates for beneficial hydrogen sulfide production, but also help achieve that all-important balance between too little and too much. Listen in to find out, and let us know what you think! ~DrKF
We're taking a trip back to high school chemistry in this episode! The chemical compound H2S, better known as the gaseous chemical Hydrogen Sulfide--the one that puts off a "rotten eggs" smell, is found in many natural environment settings. However, did you know that Hydrogen Sulfide is produced in small amounts in our bodies? This over-looked compound has a variety of important physiological effects, especially as we age. Dr. Chris Hine has been studying these benefits and how H2S may actually help stave off Glioblastoma (GBM)! Both Dr.'s Hine and Lathia have been hard at work at the Lerner Research Institute at Cleveland Clinic finding out-of-the-box ways to better treat or help prevent brain cancers such as GBM. In this episode, we take a deeper look into their work. Season Presenting Sponsor: Gamma Tile (GT Medical Technologies) Episode Sponsors: OncoSynergy, Inc. & Highmark BCBS of WNY
Unless you're new around here, you might have noticed it's been a while since our last episode. In fact, you may have thought you'd never hear from me again. But NO! I'm popping back into your podcast feed with a very important year of SIBO in review: an update on all the things that have happened in the world of IBS research since we hung up our mics after the end of the 4th and final season of the podcast. I am so thrilled to have a return guest, the king of SIBO himself, Dr. Mark Pimentel. If you're been down the SIBO rabbit hole for a while now, Dr. Pimentel likely needs no introduction. He's the director of The Pimentel Lab at Cedars-Sinai in Los Angeles, where he researches many pieces of the puzzle related to IBS, gastrointestinal motility and bacterial overgrowths. He's published dozens of studies on these subjects, and it's fair to say that much of the data-backed information we've covered throughout the 4 seasons of this podcast, has been discovered through Dr. Pimentel's work. He was last on the show almost 2 years ago in February 2020, and in that interview he promised that there would be many exciting developments for those with Post-Infectious IBS, Methane overgrowths, and Hydrogen Sulfide SIBO. So today we're going to hear a little status update. Resources, mentions and notes: The SIBO Made Simple Book – ON SHELVES NOW!! Submit your book receipt to join Gut Heal Bootcamp Pay it forward: write a book review on Amazon to support my work (you don't have to have bought it there) Join the SIBO Made Simple Facebook Community Page Subscribe to the newsletter (and receive a free low FODMAP cookbook) Follow me on Instagram to keep the conversation going Check out my blog for free recipes and SIBO resources This episode is brought to you by SIBO Made Simple – THE BOOK! Part patient guide and part cookbook (complete with over 90 low FODMAP recipes), this is your trusty road map to become your own intestinal detective, gut problem solver, and critter-free kitchen crusader. To find out more details about the podcast bonuses and to submit your receipt, click here. We are also brought to you by Kean Health, one of the companies that is making it super easy to stop guessing and start testing. KEAN HEALTH's Gut+ test gives me the literal inside scoop on what is going on in my gut, along with personalized, actionable takeaways based on my results. What I love about them is that they take complex intricate science and make it doable to make real lasting changes to my life based on the information. Right now Kean Health is offering 20 percent % OFF WITH CODE PHOEBE15. Click here to learn more.
The deadline to register to vote is coming up and never has it been more difficult to become registered. Sour gas – Hydrogen Sulfide – it stinks and it's deadly. But is the Texas Railroad Commission following the law to protect the public. And “Missing in Brooks County” – how the death toll of U.S. immigration policy deserves to be acknowledged and documented.
Linh wonders why hot springs smell bad, and Dimitri tries his best to explain it… slowly… Check out Linh's app, Not Phở, a cook that introduces the user to Vietnamese cuisine, especially dishes other than Phở. It runs on iPhone, iPad, and Mac. It also have an iMessage sticker pack so that you can share with all your friends and family. App Store: https://apps.apple.com/app/apple-store/id1525104124?pt=14724&ct=Podcast&mt=8 Follow us on Twitter: https://twitter.com/LinhAndDimiChan Follow Dimitri on Twitter: https://twitter.com/dimitribouniol Follow Linh on Twitter: https://twitter.com/linhbouniol Reference: - https://theskepticalchemist.com/why-hot-springs-smell-bad-hydrogen-sulfide/
In this episode, Dr. Goldenberg discusses his important work in the area of Hydrogen Sulfide SIBO. There is so little published data on this topic and, in an effort to remedy this, he has created a hydrogen sulfide SIBO registry where practitioners can upload information on cases that they have diagnosed whether it be an empirical diagnosis, based on a flat-line lactulose breath test, or identified on a TrioSmart breath test. It takes a couple of minutes and is super easy. So if you have hydrogen sulfide cases--go to this link (or just click it) and get that data entered. It will help us all!https://nunm.edu/research/studies/sibo-registry/Also, if you'd like to learn more about Dr. Goldenberg and his practice, go to or click this link:https://goldenberggicenter.com/It's a great episode on Hydrogen Sulfide SIBO. Enjoy!
In this episode, I interview Dr. Mark Pimentel who is a leading researcher in the field of IBS and SIBO. Dr. Pimentel has done many great things in the field of gastroenterology, not the least of which is the development of a clinical breath test for hydrogen sulfide. Before the test was available, clinicians were forced to make an educated guess on whether their patient was suffering from hydrogen sulfide SIBO. Now with the ability to test the hydrogen sulfide levels, the next big question to answer is this: What is the best treatment? Dr. Pimentel and his research group are working on this and hopefully we'll have the answer soon. A brief but information-packed episode.
During our recent Happy Hour, we had an interesting discussion on a spate of recent incidents that brought us around to talking about a skunky compound This topic was given to us by a Specialist listener on our Monthly Happy Hour. Seems there is a stinky fruit that has been giving the local college some issues, so it gave us the opportunity to talk about the cause. Thank you to our sponsor: 908 Devices, First Line Technology, Argon Electronics and Red Wave Technologies Our subscription plans are blowing up (not literally). Head over to the website to upgrade your learning by enrolling in the Technician and Specialist levels for even more content. Register and enroll at THMG e-University here. Courses being added weekly! Our hazardous materials training manual is finally available on Amazon! Click here to get your copy. Don't forget to rate, review, and subscribe. Thanks! Thanks for listening and watching! Don't just get on the job, get into the job! Was talking about a few incidents he heard about where people were eating a fruit that smelled so bad that people called the FD to investigate. The fruit is called Durian Fruit [Show pic of Durian fruit] The Durian Fruit is ugly. It's like a sea urchin. Its big, thorny, and super stinky! It depends on what side of the fence you sit, there are the people that think it smells a pleasant smell. Some say it smells like gym socks. [kind of like how europeans find our chocolate] It has been found that the overall odor of durian pulp could be mimicked by only two compounds: fruity smelling ethyl (2S)-2-methylbutanoate and roasted onion-like smelling 1-(ethylsulfanyl)ethane-1-thiol. Did you say Thiol?! Why yes I did… Then lets talk about some thiols and what they are It's a sulfur compound. Technically it's an organosulfur compound. Basically is a sulfur-hydrogen group thats attached to an organic molecule OR an alkyl group. Now this group can be called a few things, all meaning the same. You could say thiol group, sulfhydryl group or a sulfanyl group. All mean the same. All stinky. Oddly enough thiols are an analogue of alcohols. The word thiol means a mix of the works alcohol and sulfur in Greek. You may be asking yourself, where would I find some of these little bombs? You can find it in Hydrogen Sulfide or mercaptans. Now taking a look purely at the periodic table, you would find the Sulfur element immediately south of the Oxygen element. Meaning I would assume it has many of the same properties as oxygen (and I think we're pretty comfortable with oxygen as an element) But the SH functional group is MUCH different than an OH function. The purely SH group is what they would call a sulfhydryl group in the IUPAC naming system. On a side note, the word mercaptan is an ancient word. Its from the latin language. So the older ones were named by saying an alkyl group, then “mercaptan”. Old skool. You may also find them in the brewing process as a bug in the software. When you add hops to the wort there is one specific one One of the unique properties of Thiols is that they don't form hydrogen bonds, so they have a low boiling point. What does that mean to you as a responder? [the low BP means high VP therefore its coming to find my nose] Right, The 2-buten-1- thiol above is one of the components of skunk spray. Mercaptan (aka Methanethiol) is purposely added to bottled gas and natural gas in order to reveal leaks. More places are asparagus, cabbage, red grapes, apples and peaches. Are they acidic or basic? They tend to be more basic. Are they flammable? They can be. The mercaptans are, but not everyone is.
My guest is Dr. Joshua Goldenberg, who is a researcher, teacher, naturopathic doctor, and founder of the Dr. Journal Club, LLC. He's an active researcher with numerous prestigious publications, and his research focuses on SIBO, irritable bowel syndrome, evidence-informed practice, and research methodology. He is a research investigator at the Helfgott Research Institute and Visiting Research Scholar at the University of Technology Sydney. He lectures widely and currently teaches post-graduate students at Helfgott in advanced evidence synthesis methods.
On today’s podcast, we will cover listener questions, including… Will an oral antifungal medication destroy my gut? Do you recommend bismuth thiol biofilm disruptors for hydrogen sulfide SIBO? Does curcumin really help with inflammation in rheumatoid arthritis? Is there enough research to support this? What should I do if I suffer from burning pain in my stomach, and HCl, apple cider vinegar, and digestive enzymes don't help? How do I get off of the PPI I'm taking when I have reflux and EOE? My eczema of 10 years cleared up while I was on the modified fast and diet from Healthy Gut, Healthy You, but it’s starting to come back as I add foods back in. What should I do? Do you recommend the peptide BPC-157 for gut issues? https://drruscio.com/answers-on-oral-antifungal-medication-bismuth-thiols-curcumin-stomach-acid My book Healthy Gut, Healthy You is available at https://drruscio.com/getgutbook/ If you're in need of clinical support, please visit https://austinfm.com/ Looking for more? Check out https://drruscio.com/resources
Hydrogen Sulfide is a type of SIBO which has been very common lately. In this podcast episode, Amy and Dr. DiNezza discuss more on the testing accuracy, Hydrogen Sulfide Symptoms observed in their clients, effect of Low Sulfur Diet, and how to manage hydrogen sulfide SIBO. Trio Smart Test Misinterpretation Hydrogen Sulfide SIBO Symptoms Low FODMAP vs PrebioticLow Sulfur Diet Keto Diet Binge Eating How to Manage Hydrogen Sulfide SIBO
Get the details on a new media! Mike and Derek French of Wateropolis discuss Cerapure-MAC, a combination of manganese dioxide, lead free copper-zinc alloy, and carbon. It removes iron, manganese & hydrogen sulfide. Not only that - it's bacteriostatic and filters down to 10-micron. Show Notes Cerapure-MAC
Dr. Preet Khangura discusses Hydrogen Sulfide SIBO (Small Intestinal Bacterial Overgrowth) and SIFO (Small Intestinal Fungal Overgrowth) with Dr. Ben Weitz. [If you enjoy this podcast, please give us a rating and review on Itunes, so more people will find The Rational Wellness Podcast. Also check out the video version on YouTube at https://www.youtube.com/user/weitzchiro/] […]
Hydrogen sulfide's reputation may be on the cusp of getting a facelift thanks to new research out of the Johns Hopkins University School of Medicine which suggests the foul-smelling gas may protect ageing brains cells against Alzheimer's.
Hydrogen sulfide's reputation may be on the cusp of getting a facelift thanks to new research out of the Johns Hopkins University School of Medicine which suggests the foul-smelling gas may protect ageing brains cells against Alzheimer's.
Until recently, there hasn’t been a reliable way to test for hydrogen sulfide SIBO, and SIFO (small intestinal fungal overgrowth) can complicate the clinical picture. In today’s podcast, Dr. Preet Khangura, a SIBO and SIFO expert, shares about a new test for hydrogen sulfide SIBO, key clinical signs and symptoms of hydrogen sulfide SIBO and SIFO, and how to manage treatment for patients with these disorders. https://drruscio.com/updates-on-hydrogen-sulfide-sibo-sifo My book Healthy Gut, Healthy You is available at https://drruscio.com/getgutbook/ Looking for more? Check out https://drruscio.com/resources
Welcome to the next episode of WIALD , a feature of The One Thing Podcast, that stands for What I AM LEARNING DAILY. Today, I speak about Hydrogen Sulfide Breath Testing which may be the missing gas or missing link in identifying dysbiosis, sibo, or IBS factors. I recently learned a lot about it and I am excited to share. #ibs #sibo #dysbiosis --- Support this podcast: https://anchor.fm/adam-rinde/support
I speak with the brilliant Dr. Siebecker on SIBO, motility, prokinetics and hydrogen sulfide. If you want to understand the most common cause of SIBO, the role that prokinetics can play within your program, or what the future holds for our understanding of hydrogen sulfide, then this episode is for you!
In today's episode I speak with Dr. Greg Nigh about hydrogen sulfide. We discuss what roles it plays in the body, the signs and symptoms of excessive levels of hydrogen sulfide, what causes issues in sulfur metabolism and how this might lead to an overgrowth of sulfate-reducing bacteria, as well as certain interventions that may be of benefit.
Question: Is hydrogen sulfide produced in the gut a bad thing, and what to do about it?I agree that most people that have this problem have some kind of deranged sulfur metabolism, but I don't see why that makes it a physiological adaptation rather than a pathological condition. The correlation is probably a direct result of the predominance of sulfur-metabolizing bacteria in the gut, which is a bad thing that is actually causing the derangement of sulfur metabolism. Well, you could go the antibiotic route. And I think metronidozole, and let me see if I can dig this up quickly because I have done a lot of research on this issue for one of my clients. Okay. So from the research I was looking at, metronidozole is very effective against sulfur-metabolizing bacteria. But isn't that reliably delivered to the stool and maybe could be used as an enema. But I think generally, it is used. And then I think there's one other one that's sometimes used. I forgot what the other one is. I think it's... Okay. I can't find it. Anyway, you can go the antibiotic route under the guidance of a prescribing specialist. This Q&A can also be found as part of a much longer episode, here. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. There are two ways to discuss this episode: Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.
On this episode the guys talk about construction and remodeling waste. The days of throwing everything into a dumpster and sending it to a landfill are gone! Tune in and find out ways to recycle construction waste. (2:22) Why we gettin trashy? (3:07) Tonnage nugget (4:35) Common dumpster size and what it holds (6:19) Options that AREN'T the landfill (8:29) Hydrogen Sulfide - from trashy to funky (9:21) Wood in the dumpster (11:01) Drywall recycling (12:45) Recycling carpet (15:09) Why don't people recycle? (17:07) Roofing and shingles (19:09) metals (20:35) The "Compound Effect" works everywhere (21:16) Cardboard (23:23) Plastics!! (25:35) Concrete, brick and masonry...oh my! (26:25) A job site dumpster!!! WATCH and CHAT LIVE each Friday @ 5p by following this link: https://www.facebook.com/BlueCollarRealEstate/live/ _ _ _ _ _ _ _ _ _ _ _ _ _ _ SUBSCRIBE / RATE / REVIEW
ArcelorMittal South Africa on Wednesday said it will pay a fine of 3.64 million rand ($219,658) relating to charges of exceeding hydrogen sulfide minimum emissions standards at its coke plant in 2016. Chief executive of ArcelorMittal South Africa, Kobus Verster said they acknowledge that emissions at their Vanderbijlpark plant exceeded permissible H2S levels for a period of time in the past and steps were taken to address the problem but unfortunately the initiatives implemented did not adequately resolve the problems. Learn more about your ad choices. Visit megaphone.fm/adchoices
Today's podcast comes from this blog post, Hydrogen Sulfide SIBO.
Interstitial cystitis or painful bladder syndrome has been dubbed the evil twin of endometriosis, and often goes undiagnosed because the pain from the two in the pelvic can sometimes overlap and blur. I only realised that the bladder issues I was experiencing weren’t endo related when my endo symptoms resolved after I changed my diet. Over the years, my bladder pain has only worsened and has now evolved to that point where I experience pain pretty much 247. Histamines and oxalates can sometimes be behind bladder pain, and so this led me down a path of trying an elimination diet under the guidance of a nutrition at the start of this year. I started sharing my story on IG, but as the story unfolded, I decided it would be better to go quiet on the matter and share it once I was on the other side. So finally - I’m ready to talk! In today’s episode I discuss - The symptoms I was experiencing which motivated me to seek further help and try an elimination diet. Oxalates and histamines, what they are and which foods I had to avoid on this elimination diet. How I found the elimination diet - what I tried, what worked, what didn’t work. What my symptoms are like now and which ones worsened (yes, really!). The root causes we identified as being the culprits behind my bladder pain. Hydrogen Sulfide type SIBO and bladder pain. Biofilms - what they are and how they’re related to bladder pain. The next steps on my healing journey. Let's get social! Come say hello on Instagram and Facebook or sign up to my newsletter. If you feel like you need more support with managing endometriosis, you can join Your EndoLife Coaching Programme. A 1-to-1 three month health and life coaching programme to help you thrive with endometriosis. To find out more about the programme and to discuss whether it could be right for you, email me at hello@thisendolife.com or visit my website. I am now offering one-off two hour sessions for those of you who aren’t quite ready for a 12 week coaching programme. This intensive deep dive session will kick start your journey to living and thriving with endometriosis and give you a plan that you can take forward and work on alone. Click here to find out more about the programme. My cookbook This EndoLife, It Starts with Breakfast is out now! Get 28 anti-inflammatory, hormone friendly recipes for living and thriving with endometriosis. Order your copy here. This episode is also sponsored by my free guide ‘Managing Endometriosis Naturally’. This guide is perfect for anyone just starting out on this journey of managing and reducing their symptoms. Download here. This episode is sponsored by The Pod Farm. Learn all about how to start your own podcast with the complete course from The Pod Farm. Aimed at beginners, this course takes a simple and straightforward approach to planning, equipment buying, setting up, recording, editing and hosting your own podcast. With hours of audio and video materials, and downloadable guides and useful links, this multimedia approach aims to have something for every kind of learner. From now until April 15, newsletter subscribers get 20% off the course price. Visit www.thepodfarm.com to enroll or find out more This episode is sponsored by BeYou. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches and CBD range. Click here to find out more and to shop: https://beyouonline.co.uk Show Notes The Endometriosis Belly Part 2 Dr Becky Campbell
Understanding the Dangers of Hydrogen Sulfide Gas. Hydrogen sulfide (H2S) gas is produced as a result of the microbial breakdown of organic materials in the absence of oxygen. It can be found in tanks, vaults, voids, and other confined spaces at industrial facilities including power plants. Besides being flammable and corrosive, H2S is also colorless and toxic, even in relatively low concentrations, so it is extremely hazardous to workers. In fact, it is the second-most-common cause of workplace inhalation fatalities behind carbon monoxide. H2S is noticeable initially by its rotten egg smell, but the gas can deaden senses making it difficult for workers to detect without a gas monitor. Veriforce CEO Colby Lane and Chris Detillier, senior safety analyst with Veriforce, were guests on The POWER Podcast. Veriforce is a leading provider of software and services that enhance workforce and community safety. Among its offerings is a training course called H2S Clear, which provides students with life-saving information while meeting the compliance requirements of ANSI/ASSP standards. “It's extremely toxic. As little as 700 parts per million can cause someone to immediately collapse, and they can die from it,” Detillier said. “So, it is very important to have a good training program in place.” Lane explained that Veriforce's training model essentially credentials and accredits instructors. Then, those instructors provide the training to actual workers. Detillier said he's received a lot of positive feedback every time he's taught a “train-the-trainer” class for H2S Clear. “We've had guys that have been in the industry for years—some of them who have previously been through H2S training—and after class would tell me how much that they learned from the class and appreciate the content that we have in there.”
In this installment I discuss hydrogen sulfide as the chemical that has gained prominence over the past few years in chemical suicides. I also talk about onscene indications of hydrogen sulfide, as well as proper PPE selection when mitigating these situations. I briefly discuss chemical suicide awareness for other chemicals aside from hydrogen sulfide. Other topics in this installment pertain to chemical characteristics, dangerous chemical levels, and antidotes to treat viable victims. Enjoy!Online Fire Engineering "Chemical Suicide Awareness" Article Link: https://www.fireengineering.com/2015/11/23/280628/chemical-suicide-awareness/#gref
It’s the season 3 finale Q&A episode! And I have a dream guest here with me to answer all your lingering SIBO queries: the king of SIBO himself, Dr. Mark Pimentel. If you’ve already been down the SIBO rabbit hole, Dr. Pimentel likely needs no introduction. He’s the director of The Pimentel Lab at Cedars-Sinai in Los Angeles, where he researches many pieces of the IBS puzzle, including gastrointestinal motility and bacterial overgrowths. He’s published dozens of studies on these subjects, and it’s fair to say that much of the data-backed information we’ve covered in the first 3 seasons of this podcast, has been discovered through Dr. Pimentel’s work. There were a few recurring macro themes to your questions, so in today’s episode, we’re going to focus on Post-Infectious IBS, Methane overgrowth, and Hydrogen Sulfide SIBO. If you don’t hear your question, don’t stress—there’s a big possibility I’ve covered it in a past episode already. Those who are new here might want to backtrack and listen to season 1, where we cover a lot of SIBO 101 topics related to the aftermath of a diagnosis. The podcast will be on hiatus until the fall while I focus on putting the finishing touches on the SIBO Made Simple book (!!). In the meantime, stay in touch via instagram (I’m @phoebelapine) and by subscribing to my newsletter. Of course, subscribing to the podcast is the best way to be sure you’ll know when new episode start airing again. A quick taste of what we’ll cover: The proper definition of IBS, Post-Infectious IBS and SIBO Why the IBS Smart Test is useful and how to decide when to use it versus a lactulose SIBO breath test How long it takes for Post-Infectious IBS antibodies to be cleared from the body Precautions those diagnosed need to take when traveling abroad Advice for methane SIBO and constipation sufferers and the latest research about what a different beast it is Atrantil as a treatment for methane SIBO What percentage of people with SIBO have Hydrogen Sulfide and treatment plans And so much more... Resources, mentions and notes: Dr. Pimentel's website EP 27 | Bad Bacteria: Food Poisoning and Post-Infectious IBS Talley Meta-Analysis on SIBO in IBS Dr. Pimentel's new paper on IMO: Intestinal Methanogen Overgrowth SYN-010 Clinical Trial for Methane SIBO / IBS-C Atrantil - Digestive Support for Methane SIBO Phoebe’s book, The Wellness Project, on her journey with Hashimoto’s Join the SIBO Made Simple Facebook Community Page Subscribe to the newsletter (and receive a free low FODMAP cookbook) This episode is brought to you by 4 Weeks to Wellness, my online program for finding the sweet spot between health and hedonism. Need 4-weeks worth of easy low FODMAP recipes with a step-by-step meal plan laid out for you? You’ll receive a 20-recipe cookbook, complete with shopping lists, elimination diet guidance and reintroduction worksheets, in addition to the many other program resources like my symptom and activity tracker, lymphatic massage videos, doable desk stretches, and so much more. The 300+ people who have joined the tribe have reported clearer skin, calmer tummies, less bloat, tamer food cravings, and a general ease over their newfound habits. To find out more details about when the next session starts, click here. Use the code SIBOMADESIMPLE at checkout for $40 off! Disclaimer: The information in this podcast does not provide medical advice, professional diagnosis, opinion, or treatment. The information discussed is for educational purposes only and is not a substitute for medical or professional care.
Important news about Earth changes, earthquakes, volcanoes, extreme weather, anomalous events, and pictures and videos of UFOs, sky and space anomalies from around the world. If you have any pictures or videos you would like to share, email me or join our group. Links to all news stories can be found on my Facebook page.Now streaming on Spreaker and Google and iTunes Podcasts!https://www.spreaker.com/show/forbiddenhttps://www.google.com/podcasts?feed=...https://podcasts.apple.com/us/podcast...Subscribe on Bitmovio! http://v.bitmov.io/channel/forbiddenk...some music thanks to:https://www.bensound.com/Help support my research https://www.patreon.com/forbiddenknow...https://www.gofundme.com/5d7ccooOur new affiliate:Sedona UFO, Vortex and Food Tourshttp://sedonaufo.com/https://getthetea.comUse promo code: forbidden when you check out to get free shipping!Make sure your personal data is protectedVirtualshield.com https://virtualshield.com?rfsn=189156...email meforbiddenknowledgenews@gmail.comOur Facebook pagehttps://www.facebook.com/forbiddenkno...Our Facebook groupsForbidden Knowledge News https://www.facebook.com/groups/54641...Earth Changes, Natural Disasters, Extreme Weather, and Anomalous Events https://www.facebook.com/groups/22144...Thanks to Tbrat Brat and Justin Moats for monitoring LASCO, SDO, and other satellite imaging Thanks to Roberto Nuñez for sharing news, pictures and videos! Check out Roberto's Facebook page...https://www.facebook.com/roberto.nune...Thanks to:Alerta Roja
There is a third type of SIBO (besides hydrogen and methane-based SIBO) that currently does not have a test available: hydrogen sulfide SIBO. In fact, it can sometimes look like a flat line on a lactulose or glucose SIBO test. What can patients and clinicians do with the resources available? Guests Dr. Allison Siebecker, Gary Stapleton, and I discuss the testing methods available to assess and validate your likelihood of hydrogen sulfide SIBO, and their experiences in the clinic and in the lab, respectively. You’ll also learn some treatments that have shown promise. https://drruscio.com/?p=32910 My book Healthy Gut, Healthy You is available at https://drruscio.com/getgutbook/ Looking for more? Check out https://drruscio.com/resources
Mike Freemantle finds the connection between Land of Hope and Glory and the noxious, corrosive, flammable gas that stinks of rotten eggs
A certain type of SIBO, hydrogen sulfide, may be treated opposite to how we traditionally treat SIBO. Eating more carbs, less fat and more FODMAPs might be better for this type of SIBO. This is one reason why listening to your body is so important. Today I speak with Dr. Nirala Jacobi to elaborate. https://drruscio.com/hydrogen-sulfide-sibo-treatment/ My new book is finally available: Healthy Gut, Healthy You. Click here to learn more: https://drruscio.com/getgutbook/ Looking for more? Check out our resource page that includes how to become a patient, how to pick up a copy of my new book, how to sign up for my clinical training newsletter, and more. https://drruscio.com/resources
Three days on the road to Yellowstone results in the smell of Hydrogen Sulfide , bubbling mud, a bison siting, and free electricity for Middie!
In today's episode, Dr Nirala Jacobi welcomes back Dr Jason Hawrelak, to talk about Microbiome Restoration. Dr Hawrelak is a researcher, educator, naturopath, and nutritionist with over 16 years of clinical experience. He also practices at Gould's Natural Medicine - a 135-year-old natural medicine apothecary and clinic in Hobart, Tasmania, Australia. Dr Hawrelak completed his PhD examining the capacity of probiotics, prebiotics, and herbal medicines to modify the gastrointestinal tract microbiota. He is the senior lecturer in Complementary and Alternative Medicines at the University of Tasmania's School of Medicine where he coordinates the evidence-based complementary medicines programs. Dr Hawrelak also teaches the gastrointestinal imbalances unit, within the Masters of Science and Human Nutrition, and Functional Medicine Program at the University of Western States, in Portland, Oregon. Topics discussed include: The SIBO Doctor courses Microbiome Restoration - coming soon Regrowing vs killing in the microbiome. Colonic collateral when we are dealing with SIBO, and the necessity to restore the colonic ecosystem as part of the SIBO treatment. How do we learn to interpret the DNA readings and PCR reports? The SIBO Doctor Microbiome Restoration course A discussion of the modules offered in the Microbiome Restoration course Module 1 - Testing The difference between different labs Culturing vs DNA techniques Assessment, Interpretation, and Diagnosis Module 2 - Beneficial Bacteria, including Akkermansia Faecalibacterium prausnitzii Butyrate-producing microbes Hydrogen sulfide gas producers Module 3 - Pathobionts The good, the bad, the ugly Hydrogen sulfide producers Methanobrevibacter smithii coli Bacteroides Triple antibiotic therapy (for conditions such as H. Pylori and Blastocystis Hominis) and the impact on the colonic ecosystem balance of symbionts and pathobionts. Dietary changes vs probiotic supplements to elicit change in the gut microbiome. The complications between advising prebiotic nutrition for optimising microbiome restoration, whilst clients are on therapeutic diets such as the Low FODMAP diet - how to reconcile? Hydrogen sulfide breath testing - coming soon. High-fat content diets in SIBO, and how this can eventually feed hydrogen sulfide producing bacteria. Symptoms such as food reactivity and visceral sensitivity as a consequence of dietary choices in SIBO treatment, in regards to hydrogen sulfide producing bacterial blooms. The therapeutic benefits of Soy Isoflavones in relation to Methane and Hydrogen Sulfide producing SIBO patients. Equol producers - patients who have bacteria that convert soy isoflavones into the bioactive component, Equol. Adlercreutzia levels in people who eat soy products as a long-term dietary choice. Is there a connection between histamine intolerance, salicylate intolerance, and oxalate intolerance and microbiome disturbances? Post SIBO treatment food sensitivities - the colonic microflora patterns to observe. Hydrogen sulfide gas and how it causes visceral sensitivity, gut leakiness, and inflammation in the nerves. Dietary changes with people with sensitivities - a reiteration of start low, go slow. Is there any clinical significance to oxalobacter formigenes being elevated? What is the dietary impact of the extinction of oxalobacter formigenes? Testing levels of Proteobacteria to uncover the innate endotoxin load (proteobacteria - gram-negative bacteria that secrete proinflammatory endotoxins). The systemic repercussions of endotoxemia - leaky blood-brain barrier, gut damage, insulin sensitivity impacts, systemic inflammation, Alzheimer's, anxiety and depression links. Endotoxin (also known as Lipopolysaccharides - LPS) absorption and high-fat How do different Phyla respond to different diets? Potential outcomes of the ketogenic diet depending on the dietary nuances - decreased microflora diversity, increased hydrogen sulfide gas-producing bacteria, and increased numbers of proteobacteria. Akkermansia and constipation - why are these often seen together? Gut inflammation and mucus tend to increase Akkermansia if it is there - it is a mucin eater. Gut markers of inflammation, such as calprotectin. The vocabulary to use around probiotics - not re-seeding, but rather restoring. The importance of lactic and acetic acid production adjusting the pH of our microbiome to be hospitable to beneficial bacteria. D-Lactate considerations. Biogaia effectively reducing methane production, and also being used alongside proton pump inhibitors (PPIs) to prevent the development of SIBO. PPIs - when to use and when not to - listen to Dr Steven Sandberg-Lewis' podcast on SIBO and Functional GIT Exam Skills. Plantarum LP8 is being used in research to decrease Desulfovibrio, increase butyrate and bifidobacterium - can we use other strains of L. Plantarum to elicit similar changes? Plantarum strains to use in gut rehabilitation. Reuterin production. Dr Hawrelak's antimicrobial and dietary recommendations for treating Desulfovibrio. Resources Dr Hawrelak Probiotic Advisor Gould's Natural Medicine The SIBO Doctor Microbiome Restoration Course with Dr Jason Hawrelak [Opens 13 June] Sign Up for the Course and Live Q & A with Dr Hawrelak The SIBO Conference New Orleans - speakers mentioned Dr Richard McCallum Dr Matthew Bohm Labs mentioned Ubiome - microbiome DNA testing Genova Dr Satish Rao SIBO and comorbid SIFO D-Lactic Acidosis researcher Dr Steven Sandberg-Lewis Dr Steven Sandberg-Lewis' podcast on SIBO and Functional GIT Exam Skills
Dr Greg Nigh co-founded the Immersion Health Centre in 2014 after completing the Naturopathic Doctor program, and the Master of Science and Oriental Medicine Program. During his early years of work, he developed his interest and passion for researching and implementing alternative cancer therapies. Dr Nigh has spoken several times at the annual convention of the American Association of Naturopathic Physicians and the National Conference of the Oncology Association of Naturopathic Physicians on cancer cell metabolism. Dr Nigh is a prolific reader, researcher, and writer and has also contributed a chapter to the upcoming two-volume Foundations of Naturopathic Medicine textbook. Recently Dr Nigh and Dr Jacobi both presented on the SIBO SOS Summit. Dr Jacobi loved Dr Nigh's talk on hydrogen sulfide and has invited him on the show to discuss sulfur metabolism and his unique ideas about hydrogen sulfide and sulfur imbalances. Topics discussed include: How did Dr Nigh come to specialise in sulfur? All about sulfur metabolism. Sulfur chelates so well that it can get bound up in our bodies with toxic things. The GAPS diet, how it has high sulfur content, and why some patients may not feel well on the GAPS diet. Sulfur issues as the ‘canary in the coalmine' of toxicity issues in general. How the demand for sulfur is higher due to increased exposure to pollutants in modern life, and the impact this has on sulfur binding throughout the body and not just in phase 2 liver detoxification. How does endogenous sulfur processing, and sulfur production and reduction by certain gut bacteria, connect? Sulfur exposure is all dietary, and is metabolised to sulfate in the body. Sulfate is required in the body in a constant supply, and sometimes the metabolism of sulfur to sulfate is hindered. Heparan sulfate - every surface is in the body is lined with this. Elements that sulfur is used to build in the body. The primary, and alternative, pathway/s of sulfate production. Cystathionine beta synthase (CBS) pathway, what it generates (hydrogen sulfide) PAPS - the activated form of sulfate, and the pathways the body uses to get it. When people are reactive to sulfur or sulfur containing foods or thiols, they are not having an efficient process that ends up in PAPS - what are they reacting to in the pathway? If people cannot get the end product PAPS, then people can overgrow the sulfur fixing bacteria so that they produce higher levels of hydrogen sulfide and sulfide, which can be directly oxidised into sulfate by the mitochondria in the body. Dr Nigh's view is that the overgrowth of hydrogen sulfide bacteria can be seen as an adaptive overgrowth. How to reduce desulfovibrio with diet. Reasons why sulfate production can be shut down, one being glyphosate - a direct hit to sulfate production in the body, chelation of minerals that are needed for sulfur production, interference of specific amino acids involved in the sulfur cycle, and more. The impact of glyphosate on the sulfur production in the body is profound. Glyphosate - a toxic herbicide, the active ingredient in roundup. Glyphosate chelates molybdenum. We need tiny amounts of it, and if we only need tiny amounts it does not take much to chelate and use it up. Dr Nigh's view on testing. Patient symptom red flags that point to sulfur issues, for example: Hydrogen sulfide is a vasodilator, so has links to orthostatic hypotension. Any gut issues - warrants sulfur issue suspicion. Alcohol sensitivity Red, hot presentation Brain fog Histamine and sulfur overlaps. Histamine issue symptoms. Dr Nigh's protocols for enhancing sulfate production from sulfide. Taking the patient off sulfur foods for a week then gradual reintroduction. Detoxification protocols Infrared sauna Molybdenum supplementation Biotics Mo-Zyme Forte - food based tablet based on sprouted lentils 150mcg molybdenum Tablet chewed 2 times per day For those with bloating or gut issues Biotics Bio HPF - bismuth, demulcents, and others. Bismuth reduces hydrogen sulfide production in the gut. Butyrate The most underrated gut nutrient that there is. Biotics Butyric-Cal-Mag Apax EnteroVite Digestive enzyme Hydroxocobalamin injections or sublingually to lower hydrogen sulfide in the blood. Zinc acetate as a binder for hydrogen sulfide Glyphosate strongly chelates zinc. Detox support, coffee enemas, colonics, epsom salt baths (magnesium sulfate) - increasing sulfate transdermally, adrenal support if indicated Epsom salts (4 cups per bath) - a way to get sulfate in without the reactivity of digestion. Sensory deprivation tank option. Dr Yarnell's low sulfur diet Thiols and Dr Nigh's opinion on their reactivity for people. Red meat is the highest dietary source of sulfur and yet does not seem to have many people reacting to it, whereas garlic does. Why is this? Foods to watch - eggs, onion, kale, garlic, cabbage, brussel sprouts, cabbage, brassica family. Kale accumulates the heavy metal thallium (from waste-water used for crops). Do Allicin extracts still elicit issues in people with sulfur issues? Highly important to include any sulfur food items that are tolerated for the sulfur content (required by body). Dr Nigh's sulfur protocol and his success with SIBO patients. What is the connection between Dr Nigh's success with methane dominant SIBO clients and the sulfur protocol? How might glyphosate toxicity play into this? Methanobrevibacter smithii - not a pathogen, why? SIBO bacteria - why do we only grow certain bacteria? Dr Nigh's sulfur metabolism nuggets. Resources Dr Greg Nigh Immersion Health Portland, Oregon drnigh@immersionhealthpdx.com SIBO SOS Summit Dr Yarnell Naturopathic Foundations of Gastrointestinal Diseases? Foundations of Naturopathic Medicine Biotics Research Mo-Zyme Forte Bio HPF Apax EnteroVite
In this episode Dr Nirala Jacobi is in conversation with Dr Christopher Shade. Dr Shade is the CEO and founder of Quicksilver Scientific, a lab that specialises in the environmental, biological, and analytical chemistry of mercury and all of its forms, and its interaction with sulphur compounds, particularly glutathione, and its enzyme systems. Dr Jacobi met Dr Shade at the Bioceuticals Research Symposium in Sydney, 2017, and was riveted by his presentation on detoxification. Topics discussed in this episode include: The liver, gallbladder, and GI connection, and how to align them so as to clear gastrointestinal issues. How failure to move bile is at the heart of detox reactions Bile as a detergent in the small intestine and how bile can be a core issue in SIBO. Bile acid destruction and fat malabsorption in SIBO. Emunctories and what this means. Drainage areas and how the extracellular space is cleared. Metal binder for the GI tract that is far better than chlorella - IMD microsilica Toxin conjugates and their interaction with bile salts. Phosphatidylcholine (PC), its requirement to fluidise the bile, and choline's relationship to cholestasis. Lipopolysaccharide (LPS) endotoxins from leaky gut (from SIBO) creating inflammation in the hepatocytes and the flow on effects from this. Phase 3 detoxification - The role of bile flow in lessening detoxification reactions through lowering toxic conjugate buildup in the blood, and instead moving them through the proper elimination channels. The importance of addressing emunctories in treating skin conditions. How LPS impairs phase 3 in the liver. Neurological consequences of leaky gut, SIBO, and of a backfiring liver. Neuroinflammation, LPS, and a leaky blood brain barrier. Movement of metals into the urinary flow and how it has nothing to do with glomerular filtration rate (GFR), even though this is what is commonly measured for kidney function. Organic anion transport peptide's (OATP) role in bringing toxic conjugates from the blood into the proximal tubular epithelial cells in the kidneys, then the movement of the toxic conjugates into the urinary flow through the MRP2 transporter. MRP2 and how LPS and metals can block it. How the same things that shut down liver transport of toxic conjugates, can also shut down kidney transport. Does LPS affect GFR? Active transport of toxins happens in the proximal tubules of the kidney, not in the glomerulus. Kidney disfunction and how SIBO can be related to proximal tubule damage in the kidney due to the build up of LPS. Proximal tubule function test available - Mercury Tri-Test from Quicksilver Scientific. Genetic Single Nuclear Polymorphisms (SNPs) and how the transport protein SNPs are commercially uncharted as yet. How inflammation blocks detoxification. Chronic infections turning down detoxification. Ways to address phase 3 detox. Address under-functioning gallbladder with PC, for example. Address leaky gut so that toxins dumped into small intestine do not recirculate. Strong bitters before meals. Take multi-toxin binder (30 minutes after taking bitters) - this is important to do 30 minutes after bitters. Dr Nirala Jacobi uses Toxaprevent, but not in SIBO-C patients. Dr Shade uses: Charcoal Clay Chitosan Metal binder eg. IMD (much stronger than chlorella), Chlorella. Acacia gum For leaky gut Low FODMAPS Bifidogenic prebiotic Powdered Aloe Marshmallow root Slippery elm Is there a test to assess phase 3 detox function? NRF2 upregulators and their role in cellular detoxification, to be implemented AFTER liver and kidney detoxification is streamlined. The importance of NRF2 and the effects it has on the body. Dr Shade's universal binder - Ultra Binder How to access Dr Shade's products. Dr Shade's recipe for a self made toxin binder. The importance of Myrrh in the bitters The bitter detoxifier in ayurvedic medicine, qi and blood mover in chinese and ayurvedic medicine, and strong antimicrobial. Cautions with long term myrrh supplementation. Other herbals bitters to include: Dandelion Solidago (Golden Rod) Gentian Dr Jacobi's bitters blend Dandelion Oregon grape Gentian Baical Skullcap Bitters as opening up the bile, tonifying the kidneys, and restoring ileocecal valve function. What is the function of bitter receptors on the ovaries? If SIBO clients are Hydrogen Sulfide dominant note that the bacteria involved here are bile loving, so any cholagogues will exacerbate the SIBO issue. Does charcoal absorb all of your minerals? Using charcoal as the primary binder - amounts to take and rationale for diversifying binder portfolio. Is mercury stored in biofilm? Is it advised to disrupt biofilm, or is it dangerous to do so? EDTA as a biofilm breaker. Plaques in the vascular system are actually biofilms. What mercury testing is offered at Quicksilver Scientific? Is it worth testing for mercury toxicity? When is it good to test people for mercury toxicity? How healing the GI tract can heal the kidneys. What is the evil of amalgam fillings? Why people with amalgams often have to urinate a lot at night. The body has it's own inbuilt chelating system - glutathione, glutathione-s-transferase, and the transport proteins. What are the myths of chelation agents? Is lipoic acid a chelator, or is it upregulating the body's natural chelation system? The importance of lining up all the drainage, and lining up all the phases of detoxification. Hydrotherapy for the lymphatics. The issues in Australia with lead and aluminum - Dr Shade's recommendation on how to test these areas: Nutripath's Blood Metals Assay Excess copper in the presence of low zinc can become synergistically toxic with all toxic metals. Whole blood vs intracellular for testing? How do you measure intracellular stores? Residence time in the blood of different metals. Dr Shade's last pearls of wisdom - start with drainage, then move to mobilisation after levels come down first with good drainage. Resources Quicksilver Scientific Dr Shade's Quicksilver Scientific Youtube channel Proximal tubule function test available - Mercury Tri-Test from Quicksilver Scientific. Tri-test is available through Nutripath Ultra Binder by Quicksilver Scientific for detoxification Bitter X by Quicksilver Scientific Klinghardt therapy
Today we will cover listener questions, which include antioxidants, gene-tailored diets, joint pain and gut health, hydrogen sulfide SIBO, probiotics during a hospital stay, and more…
For the past decade, Japan has been experiencing a decline in its population. Listen in as we talk about the crisis and what some of the reasons may be for this occurrence.Billy also shares his experience of when he returned to China. He talks about some of the things he did and shares some tips on how to survive if you ever plan to visit.Lastly, we look at the prospect of human hibernation. What would you do if you can freeze yourself without dying?Dating in Japanhttp://topdocumentaryfilms.com/no-sex-please-japanese/Man dies under his six-ton pile of porn magazineshttp://www.dailymail.co.uk/news/article-4278524/Man-dies-six-ton-pile-porn-magazines.htmlHydrogen Sulfide–induced Suspended Animationhttps://pure.uva.nl/ws/files/1632134/118399_07.pdfLemurs Hibernationhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010898/https://phys.org/news/2013-05-primate-hibernation-common-previously-thought.html▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬Follow us!Download: http://blog.faultylogix.comInstagram: https://www.instagram.com/faultylogixTwitter: https://twitter.com/Faulty_LogixFacebook: https://www.facebook.com/faultylogixiTunes: https://itunes.apple.com/ca/podcast/faulty-logix/id1160004810?mt=2#▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬Music:Early Riser Kevin MacLeod (incompetech.com)Licensed under Creative Commons: By Attribution 3.0 Licensehttp://creativecommons.org/licenses/by/3.0/
A return to the damaged bridge of the Konyechny brings new surprises, including new smells. And Christopher reveals the secret he's been keeping from Sophia. Support this podcast
A return to the damaged bridge of the Konyechny brings new surprises, including new smells. And Christopher reveals the secret he's been keeping from Sophia. Support this podcast
In this episode we begin to explore the most common chemicals that we in the streets respond to. We begin this with Hydrogen Sulfide. Please subscribe to all of our Haz Mat shows: The Haz Mat Guys Podcast, THMG Hot wash, THMG Instructors corner. You can now check us out doing the show live on Google Hangouts Live periodically. We also do a weekly round table discussion with experts from around the country live on Google Hangouts under The Haz Mat Guys Nation every Tuesday night at 21:15EST. You can find us on YouTube. Thanks for listening and watching!
In this episode we begin to explore the most common chemicals that we in the streets respond to. We begin this with Hydrogen Sulfide. Please subscribe to all of our Haz Mat shows: The Haz Mat Guys Podcast, THMG Hot wash, THMG Instructors corner. You can now check us out doing the show live on Google Hangouts Live periodically. We also do a weekly round table discussion with experts from around the country live on Google Hangouts under The Haz Mat Guys Nation every Tuesday night at 21:15EST. You can find us on YouTube. Thanks for listening and watching!
Carl White explains how the gaseous signaling molecule hydrogen sulfide suppresses calcium signaling in adipose tissue macrophages to limit inflammation.
The gasotransmitter hydrogen sulfide signals by sulfhydrating target proteins.
Life Lines - The Podcast of The American Physiological Society
Segment 1: What a Gas. University of Alabama – Birmingham researchers Jeannette Doeller and David Kraus talk about the amazing properties of hydrogen sulfide gas. Although it’s lethal in even minute quantities, our bodies produce it and use it to good effect. Episode 10 graphic courtesy of David Kraus. Begins at 1:15.Segment 2: Research Progress on Colon Cancer. John Carethers of the University of California San Diego explains his research findings on colon cancer and the role that the DNA mismatch repair system plays. Begins at 15:24.Total time: 25:10Body Notes, the theme music at the beginning and end of the show, was composed by APS member Hector Rasgado-Flores and was performed by the San Diego Chamber Orchestra.
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