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In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Jup Kuipers, Boomer Anderson, Dr. Allen Bookatz, and Dr. Scott Sherr explore a difficult question: can we influence the biology of an aging brain carrying APOE4 risk? APOE4 is not simply a diagnosis, and a genetic result does not tell us what is happening in someone's brain today. The team looks at how APOE4 may affect lipid transport, microglial behavior, vascular integrity, glucose utilization, mitochondrial function, circadian biology, and epigenetic maintenance. The discussion also lays out a practical three-phase framework: establish the phenotype, reduce ongoing stressors, restore circadian and bioenergetic alignment, and track whether cognitive, functional, metabolic, vascular, and biological age measures actually improve over time. Join us as we delve into: APOE4 Risk vs Diagnosis: What one versus two APOE4 copies may mean, and why genotype is not the same as the current clinical stage. Cellular Energy and Epigenetic Maintenance: Why disrupted energy metabolism can affect the conditions needed for normal transcription and epigenetic maintenance. Circadian Biology, NAMPT and NAD+: How CLOCK and BMAL1 influence NAMPT and the NAD+ salvage pathway, and why disrupted circadian rhythms can affect cellular maintenance. Health Optimization Medicine vs Disease-Centered Prevention: Why the HOMe approach focuses on the cellular environment and the conditions that create and sustain health. The Three-Phase Clinical Framework: How to establish a baseline phenotype, reduce exposomic stressors, restore circadian and bioenergetic alignment, and track outcomes over time. The Skeptical Position: The team considers the argument that APOE4-driven pathology may be too genetically determined for lifestyle and metabolic tuning to meaningfully change the trajectory. What Does a "Reset" Actually Mean?: Why a reset is a claim that needs to be demonstrated through durable improvements in cognition, function, and biomarkers over time. This episode is for you if: You have undergone genetic testing and want to better understand what an APOE4 result does and does not tell you. You are interested in the relationship between APOE4, brain aging, metabolism, vascular health, and mitochondrial function. You want to understand how circadian biology, NAD+ salvage, and epigenetic maintenance may intersect with brain health. You are interested in a measurement-based Health Optimization Medicine approach to genetic risk. You want to understand why phenotype, longitudinal tracking, and objective biomarkers matter when evaluating interventions. You can also find this episode on… YouTube: https://youtu.be/byEspMGRbtI Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, and Jodi Duval sit down to discuss what happens when the body's cellular defense systems remain activated after the original threat has passed. Fatigue and brain fog are often treated as problems that require more stimulation, more exercise, or more supplements. But what if low energy is sometimes an adaptive response? The HOMeHOPe faculty explores the Cell Danger Response, how mitochondria and purinergic signaling respond to threats, and why pushing harder can sometimes work against recovery. The discussion also introduces a practical three-phase approach to moving from persistent cellular defense toward greater metabolic and bioenergetic flexibility. Join us as we delve into: Why Cells Get Stuck in Survival Mode: How infection, toxin exposure, tissue injury, and other stressors can shift cellular priorities toward defense, and what happens when those signals persist after the original crisis. The Cell Danger Response: How mitochondrial function, ATP signaling, inflammation, and purinergic pathways can change during cellular stress. Why More Energy May Not Be the Answer: Why fatigue can sometimes represent an adaptive biological response rather than simply a deficiency that can be corrected with more stimulants or supplements. ATP Has Two Different Messages: How intracellular ATP supports cellular work while extracellular ATP can act as a danger signal through purinergic receptors. The Three Phases of Recovery: How exposomic unburdening, assessment of intracellular and metabolic function, and reinforcement of cellular safety can provide a framework for recovery. Measure, Don't Guess: Why organic acids, acylcarnitines, redox markers, amino acids, micronutrient patterns, and membrane lipids can help identify metabolic constraints and guide targeted interventions. Circadian and Autonomic Regulation: Why morning light, sleep, appropriately graded activity, autonomic regulation, and circadian timing are part of restoring biological capacity. The Limits of the Cell Danger Response Model: Where the evidence is mechanistic or emerging, why the framework should not be used to explain every chronic symptom, and why stronger clinical evidence is still needed. This episode is for you if: You work shifts, overnight schedules, or other situations where acute sleep deprivation is sometimes unavoidable. You want to understand how sleep loss affects brain energy metabolism and cognitive performance. You are interested in the relationship between creatine, phosphocreatine, ATP, and brain function. You want to understand the potential and limitations of using creatine during acute cognitive stress. You are interested in cellular bioenergetics and the Health Optimization Medicine approach to precision health. You can also find this episode on… YouTube: https://youtu.be/0mn-8B6K0bU Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Dr. Jup Kuipers explore how acute sleep deprivation affects brain energy metabolism and whether creatine monohydrate can help preserve cognitive function when sleep loss is unavoidable. Rather than relying on stimulants like caffeine or modafinil to push through fatigue, the team examines whether directly supporting the brain's phosphocreatine and ATP systems can maintain cellular energy and cognitive performance during acute sleep deprivation. The discussion looks at recent research on single-dose creatine, brain bioenergetics, blood-brain barrier transport, clinical dosing, and the limits of using creatine as an acute rescue tool. Join us as we delve into: Sleep Deprivation as a Bioenergetic Crisis: Why acute sleep loss is more than simply feeling tired, and how depletion of phosphocreatine and ATP can affect executive function and cognitive performance. The Creatine Rescue Effect: What a 2026 randomized crossover study found when healthy participants received a single dose of creatine after prolonged sleep deprivation. Creatine, ATP & the Brain: How creatine acts through the creatine kinase system to help maintain high-energy phosphates during acute metabolic stress. The Blood-Brain Barrier Under Stress: Why sleep deprivation may change the conditions for creatine transport into the brain and create a window for acute supplementation. The Clinical Protocol: What the episode discusses regarding single-dose creatine monohydrate, timing before an acute cognitive stress period, hydration, magnesium, and other cofactors. Creatine Is Not a Substitute for Sleep: Why acute creatine rescue may help preserve cellular function during unavoidable sleep loss, but cannot replace the restorative functions of deep sleep and REM sleep. Health Optimization vs. Disease Prevention: Why HOMeHOPe approaches acute physiological stress by supporting cellular function before the system reaches a state of failure. This episode is for you if: You work shifts, overnight schedules, or other situations where acute sleep deprivation is sometimes unavoidable. You want to understand how sleep loss affects brain energy metabolism and cognitive performance. You are interested in the relationship between creatine, phosphocreatine, ATP, and brain function. You want to understand the potential and limitations of using creatine during acute cognitive stress. You are interested in cellular bioenergetics and the Health Optimization Medicine approach to precision health. You can also find this episode on… YouTube: https://youtu.be/LvEBMroaLA4 Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers explore a misunderstood cause of chronic fatigue and leaky gut: the bioenergetic failure of your colonocytes. While many practitioners throw random probiotic strains and anti-inflammatory herbs at gut issues, metabolomic research shows this approach fails to address the root problem. The team explains how a starved microbiome forces gut cells to switch energy systems, leaking oxygen into the colon, destroying strict anaerobes, and allowing endotoxins to flood the bloodstream and drain your cellular vitality. From holobiont metabolomics to targeted mucosal protocols, this discussion reframes gut health through the lens of mitochondrial beta oxidation rather than simply managing inflammation. Join us as we delve into: The Gut Hypoxia Trap: How starved colonocytes switch to anaerobic glycolysis and leak oxygen into the gut, killing off the strict anaerobes that make butyrate. The Endotoxemia Dilemma: How opportunistic bacteria pry apart tight junctions, allowing lipopolysaccharides (LPS) into the bloodstream and locking your cells into a permanent Cell Danger Response. Why Probiotics Fall Short: Why conventional protocols fail to repair the mucosal shield and how to properly signal Akkermansia muciniphila with complex polyphenols. The 4-Step Clinical Protocol: How to use stool metabolomics, pomegranate ellagitannins, oral tributyrin, and L-glutamine to rebuild the gut barrier from the ground up. Pathogenesis vs Salutogenesis: Why Health Optimization Medicine focuses on restoring root cause physiological health rather than perpetually suppressing symptoms. This episode is for you if: You are dealing with chronic fatigue, brain fog, and unyielding food intolerances despite taking probiotics. You want to understand the true biochemical mechanism behind leaky gut and systemic endotoxemia. You are a practitioner looking to replace guesswork with objective metabolomic testing and precision mucosal protocols. You can also find this episode on… YouTube: https://www.youtube.com/watch?v=_wZH8tJTFWw&feature=youtu.be Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval explore one of the most overlooked causes of declining cellular energy: the structural breakdown of the mitochondrial membrane. While many people invest in premium longevity supplements like NAD+, NMN, and CoQ10 to improve energy production, emerging research suggests these compounds cannot overcome a damaged mitochondrial membrane. The team explains how age-related phosphatidylcholine depletion weakens the mitochondrial lipid bilayer, causing proton leakage, oxidative stress, and reduced ATP production, even when the biochemical machinery appears intact. From membrane lipidomics and clinical metabolomics to phosphatidylcholine replacement and methylation support, this discussion reframes mitochondrial health through the lens of structural integrity rather than simply adding more fuel. Join us as we delve into: The Leaky Mitochondria Problem: Why declining phosphatidylcholine causes proton leaks that reduce ATP production and accelerate mitochondrial aging. Why NAD+, NMN & CoQ10 Sometimes Fail: How expensive mitochondrial supplements cannot restore energy when the mitochondrial membrane itself has become structurally compromised. Pathogenesis vs. Salutogenesis: Why Health Optimization Medicine focuses on building the biology of health instead of simply preventing disease. Clinical Metabolomics & Membrane Lipidomics: How measuring functional biomarkers provides deeper insight into cellular health than conventional blood tests alone. Phosphatidylcholine Replacement Therapy: Why rebuilding mitochondrial membranes with pharmaceutical-grade phosphatidylcholine, methyl donors, and chronobiology may improve bioenergetics. The Prevention Paradigm Shift: Why optimizing membrane integrity may become a foundational strategy for supporting healthy aging and cellular resilience. This episode is for you if: You are taking NAD+, NMN, CoQ10, or other mitochondrial supplements but still struggle with fatigue or poor recovery. You want to understand why mitochondrial membrane health may be more important than simply increasing energy substrates. You are interested in clinical metabolomics, membrane lipidomics, and the future of precision lifestyle medicine. You want to learn how phosphatidylcholine and methylation support contribute to healthy mitochondrial function. You can also find this episode on… YouTube: Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, our clinical team (Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Jodi Duval, and Dr. Jup Kuipers) takes a deep dive into the shocking new 21-year pre-diabetes follow-up study (DPPOS) published in the Journal of the American Medical Association on June 15, 2026. Moving past the mainstream longevity hype surrounding Metformin as an anti-aging cure-all, the faculty breaks down why chemically poisoning your enzymes is a profound mismatch for healthy, active individuals. From the bioenergetics of exercise to the clinical application of precision metabolomics, this roundtable shifts the conversation from off-label drug prescriptions to cultivating true cellular safety and mitochondrial hormesis. Join us as we delve into: The Metformin Illusion: The long-term results of the DPPOS study proving Metformin completely failed to outperform a placebo for reducing multimorbidity risk, while intensive lifestyle intervention reduced multiple chronic disease risks by over 20%. Mitochondrial Blockade: How Metformin's inhibition of Complex I of the electron transport chain chemically throttles your cells, cutting cardiovascular fitness gains (VO2 max improvements) in half compared to exercise alone. The mTOR Obstacle: Why daily off-label Metformin use actively blunts muscle hypertrophy and strength gains in response to resistance training by blocking key adaptation pathways. The Rating of Perceived Exertion (RPE) Spike: How chemically throttling your mitochondria drives up lactic acid, leaving active biohackers with nagging, unexplained fatigue during workouts. Pathogenesis vs. Salutogenesis: Why functional and preventive medicine remain trapped in disease-centered thinking, and how Health Optimization Medicine shifts the focus to detecting and correcting cellular imbalances. The 3-Phase Metformin Transition Protocol: A step-by-step clinical sequence using early morning circadian anchors, urinary organic acid testing, targeted orthomolecular cofactors, and pulsed phytoceuticals strictly on rest days. This episode is for you if: You are currently taking Metformin or berberine off-label for anti-aging but feel like your gym gains and recovery have plateaued. You want to understand the exact biochemical mechanisms of how daily chemical inhibitors block the cellular stress signals required for exercise adaptations. You want to learn how to transition off chronic metabolic blockades and restore biological peak quality of life naturally. You can also find this episode on… YouTube: https://youtu.be/v1e132gqY_k Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Jup Kuipers, and Jodi Duval take a deep dive into the gut-brain-microbiota axis. Moving past the simplistic, pathogenic "pill-for-an-ill" approach of conventional psychiatry and the mainstream hype around over-the-counter probiotics, the faculty breaks down why establishing enteric safety must always precede biochemical optimization. Join us as we delve into: The Tripartite Axis: How the enteric microbiota, gut barrier, and central nervous system communicate at a molecular and metabolomic level to dictate brain state and mood. Epigenetic Signaling: How gut microbes act as active metabolic factories, fermenting dietary fibers into short-chain fatty acids (SCFAs) like butyrate that cross the blood-brain barrier to upregulate BDNF and support synaptic plasticity. The IDO Serotonin Hijack: How gut-driven inflammation activates indolamine 2,3-dioxygenase (IDO), shunting tryptophan down the kynurenine pathway to produce neurotoxic quinolinic acid instead of serotonin and melatonin. The Microglial Fire: How circulating cytokines cross the blood-brain barrier at the circumventricular organs, placing the brain's microglia into an active defense state that triggers cognitive fatigue and brain fog. The 3-Phase Gut-Brain Protocol: Why seeding probiotics into inflamed soil fails, and how to logically sequence clearing overgrowth, rebuilding mucosal integrity with L-glutamine, and seeding validated strains. This episode is for you if: You are running on high-dose over-the-counter probiotics for mood issues but feeling no relief or worsening symptoms. You want to understand the exact cellular and biochemical mechanisms connecting leaky gut to leaky brain and psychiatric distress. You want a practical, clinically sequenced blueprint to restore gut barrier safety before attempting to optimize your neurochemistry. You can also find this episode on… YouTube: https://youtu.be/A43LDN6FgvA Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
Today we have Dr. Scott Sherr, an internal medicine physician who specializes in Hyperbaric Oxygen Therapy. Scott is the director of Integrative Hyperbaric Medicine and Heath Optimization at Hyperbaric Medical Solutions. It is a division of Hyperbaric Medical Solutions, an independent, hyperbaric oxygen therapy provider that aims to educate people about the benefits of hyperbaric oxygen therapy via telemedicine consulting. He also is COO of Troscriptions, which provides physician-formulated products including popular methylene blue products. In today’s interview, Scott talks about how he uses Hyperbaric Oxygen Therapy (HBOT) to treat a number of health conditions. He also shares how he incorporates methylene blue into some of his treatment strategies and explains how HBOT is now being used as a complementary treatment for autoimmune diseases by helping reduce inflammation, improve blood flow and support immune function. Show notes: [00:03:29] Dawn tells Scott that she heard a story that Scott had his spine adjusted when he was just five minutes old. She asks Scott if he can share what happened. [00:04:15] Dawn mentions that Scott grew up in New York on Long Island and that as a child he spent a lot of time at his father's chiropractic office. Dawn asks Scott about his father and his practice. [00:05:38] Ken notes that Scott was into sports as a kid and asks him to talk about his childhood and what he was like as a kid. [00:07:09] Dawn notes that after high school, Scott left New York for the West Coast, landing at UCLA. Dawn asks Scott to talk about what led him there. [00:08:00] Dawn explains that Scott initially started to major in biology but quickly changed majors. Scott explains why he changed majors. [00:08:41] Dawn asks Scott why he chose to attend the University of Maryland for medical school after graduating from UCLA. [00:09:26] Dawn asks Scott about the story of how he met his wife at the University of Maryland. [00:09:50] Dawn pivots back to Scott's love of music, mentioning that Scott and three other medical school students at Maryland formed a band called The Airport Rocking Chairs. Scott describes how the band came together and how they performed at gigs around the Baltimore/D.C. area. [00:11:16] Ken asks Scott to talk about how his early ambition upon entering medical school was to find a way to bridge the gap between conventional and alternative/chiropractic medicine. [00:12:54] Ken explains that in Scott's third year of medical school, he did rotations at the University Shock and Trauma Facility. Ken asks Scott to talk about why this was such an important experience for Scott. [00:14:32] Dawn explains that hyperbaric chambers are used to treat injuries like necrotizing fasciitis and severe wounds. Dawn asks Scott to talk about finding a hyperbaric chamber in the basement of the University Shock and Trauma Facility and how that led to his fascination with the potential for hyperbaric oxygen therapy. [00:15:51] Dawn asks Scott to talk about how his initial research on hyperbaric therapies led him to conclude that they were being vastly underutilized in conventional medicine. [00:16:31] Dawn mentions that people are likely familiar with hyperbaric oxygen therapy (HBOT) in terms of treating divers suffering from decompression sickness. She asks Scott to give a primer on the mechanisms by which HBOT affects the body and why it has potential to treat other conditions besides decompression sickness. [00:19:38] Ken asks Scott to talk more about other conditions, both acute and chronic, that HBOT might be helpful in treating. [00:22:51] Dawn asks about Scott's experience as a hospitalist, which is an internal medicine physician who acts as a primary care physician in a hospital, and how this experience gave him a unique perspective on the strengths and limitations of modern medicine. [00:25:13] Ken asks Scott if it's fair to say that his experience as a hospitalist was foundational in developing his understanding of patient care and healthspan. [00:26:51] Dawn explains that when Scott's wife received a fellowship at Stanford University, Scott eventually left his career as a hospitalist to serve as the medical director for a hyperbaric medicine facility in the San Francisco Bay area. Dawn asks Scott to talk about how this experience deepened his understanding and expertise in hyperbaric oxygen therapy. [00:28:26] Ken asks Scott to talk about his relationship with Dominic D'Agostino, who was our recent guest on STEM-Talk episode 196, and who is very active in the field of hyperbaric oxygen therapy. [00:30:48] Dawn mentions that during Scott's work as a hospitalist, he began to develop a more integrated approach to hyperbaric medicine, taking nutritional status, sleep patterns, mitochondrial function, and a number of other factors into consideration. Doing this work, Scott noticed that a number of patients would require weeks or months of preparation before beginning HBOT, contrary to the status quo of the time. Dawn asks Scott to talk about his insights and how this experience changed his views on medicine. [00:33:19] Dawn asks Scott to talk about the evolution of his work in developing an integrative hyperbaric medicine model and how he caught the attention of HBOT practitioners around the world. [00:35:21] Ken notes that interest in hyperbaric oxygen therapy has grown substantially in the last 20 years and goes on to mention that a particularly promising application of HBOT is as a complementary treatment for autoimmune diseases, being shown to reduce inflammation, improve blood flow and support immune function. Ken asks Scott to talk in depth about HBOT in the context of autoimmune disease treatment. [00:39:13] Following up on Scott's mention of epigenetic changes following HBOT, Ken asks if this has been directly measured and if so, how long are these changes sustained. [00:41:14] Dawn asks Scott about the potential for HBOT to be used for athletes looking to speed up their recovery times from injuries. [00:43:19] Dawn asks Scott if there are certain populations who should avoid HBOT. [00:46:27] In order to optimize HBOT, Dawn explains that Scott works with people to tailor their treatment to their individual needs and asks Scott to walk listeners through how this process works in practice. [00:50:00] Ken notes that most HBOT studies describe dosages of HBOT in terms of oxygen concentration, oxygen pressure and number of sessions. He asks Scott how he defines a “dose” biologically and what metrics he uses to tell whether a patient has received enough treatment to induce durable change? [00:53:40] Ken asks Scott if his experience treating patients has informed him on different characteristics that can predict whether a patient will have a robust response to HBOT. [00:56:01] Dawn mentions that the benefits of HBOT are often explained in terms of either improved oxygen delivery or improved mitochondrial signaling and neuroplasticity. Dawn asks Scott what mechanisms are most important in the context of chronic neurological disease. [00:58:04] Dawn asks Scott for his thoughts on the hyperoxic-hypoxic paradox (HHP) as an explanation of HBOT-induced adaptation. [01:00:28] Ken asks Scott if he could only measure three variables before and after HBOT treatment, what would they be. [01:03:43] Ken goes on to asks Scott what he sees as the most important unanswered question in HBOT today. [01:06:22] Dawn mentions that in 2017 Scott met Dr. Ted Achacoso, who is the founder of Health Optimization Medicine. Dawn asks Scott to explain how Ted introduced him to a fundamentally different framework for understanding health. [01:10:08] Circling back to the topic of bridging the gap between conventional and alternative medicine, Dawn mentions that Scott has become part of a practice that isn't afraid to tap into therapies that break from conventional medicine. As an example, Dawn explains that Scott sometimes integrates psychedelic therapy with HBOT. Dawn asks Scott to talk about the framework he uses, combining HBOT with psychedelic therapy. [01:13:56] Ken mentions that Scott also incorporates methylene blue into some of his treatment strategies, Ken directs listeners interested in learning more about how methylene blue can improve cognitive function and energy production to listen to STEM-Talk episode 191 with Francisco Gonzalez-Lima. Ken asks Scott to talk about his use of methylene blue in his practice. [01:20:15] Dawn asks Scott where people can go to learn more about him and his practice. [01:22:33] Ken asks Scott if he has any new projects looming on the horizon. [01:23:54] Dawn closes our interview with Scott by asking if he still plays guitar and if his old band The Airport Rocking Chairs have any plans for a reunion. Links: Scott Sherr bio Learn more about IHMC STEM-Talk homepage Ken Ford bio Ken Ford Wikipedia page Dawn Kernagis bio
In this episode of the Health Optimization Medicine Podcast, Dr. Allen Bookatz, Dr. Ted Achacoso, and Jodi Duval tackle the widespread trend of supplement fatigue. As biohacking becomes a mindset of treating symptoms with heavy stimulants and endless pills, the faculty breaks down why forcing adaptation on an exhausted system only drives the body deeper into a chronic state of inflammatory defense. From the biophysics of the Cell Danger Response (CDR1) to practical parasympathetic upregulation, this roundtable shifts the focus from treating disease to establishing true autonomic safety. Join us as we delve into: The Cell Danger Response (CDR1): How a sympathetic fight-or-flight state physically stiffens cell membranes and halts aerobic respiration. The Vagal Superhighway: How sympathetic dominance halts gut motility, triggers dysbiosis, and blocks neurotransmitter synthesis. The Autonomic Safety Protocol: The critical importance of chronobiology, early morning sunlight, and circadian anchors. Vagal Upregulation & GABA Support: Utilizing transcutaneous auricular vagus stimulation (taVNS), L-theanine, and Kava to quiet the central alarm and exit CDR1. The Myth of Extreme Hormesis: Why intense stressors like ice baths and strict fasts act as active threats, not adaptation triggers, when your cells are already depleted. This episode is for you if: You are running on a continuous cycle of intense workouts, strict fasts, and multiple wearables, yet feel more exhausted. You want to understand why your cells cannot use nutrients for energy production when they perceive an active attack. You want to learn how to pulse carefully calibrated hermetic stressors only after restoring baseline energy reserves. You can also find this episode on… YouTube: https://youtu.be/uE3LhioxwZQ Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, our faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, Dr. Allen Bookatz, and Jodi Duval, tackle the recent trend of therapeutic plasma exchange and "blood washing". Moving past the mainstream marketing of plasmapheresis as a longevity cure-all, the team breaks down why mechanical filtering is only a surface-level fix for microplastic toxicity. From the autonomic anxiety caused by biological lockdown to the clinical application of precision metabolomics, this roundtable shifts the conversation from invasive procedures to measurable, cellular safety signals. Join us as we delve into: The Protein Corona: How circulating microplastics masquerade as pathogens, triggering localized purinergic signaling and the release of extracellular ATP. The Cell Danger Response (CDR1): Why the body halts oxidative phosphorylation and locks down the cell membrane when invaded, and why blood washing can't touch toxins stuck inside tissue matrices. The Problem with Plasmapheresis: The clinical realities and physiological costs of invasive vascular filtering, including the removal of essential immunoglobulins and clotting factors. The True Detox Protocol: Utilizing organic carbon binders (humic and fulvic acids), phase two liver conjugation (glucuronidation/sulfation), and barrier integrity support to properly excrete microplastics. Pulsed Antioxidant Support: When and why to use targeted NAD, alpha-lipoic acid, NAC, and ubiquinol to transition cells out of a defensive lockdown. This episode is for you if: You are considering expensive therapies like plasmapheresis to clear environmental toxins. You want to learn how to test your cellular metabolomics for organic acids and brain inflammation. You want to understand how your unique exposome interacts with your cellular safety mechanisms. You can also find this episode on… YouTube: https://youtu.be/5b4jWqByRAU Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, and Jodi Duval) tackles one of the most paradoxical trends in modern biohacking: sleep tracking. Moving past the mainstream obsession with daily device scores, the team breaks down the biochemical realities of how tracking your HRV might actually be sabotaging your sleep architecture. From the autonomic anxiety caused by digital wearables to the clinical application of precision chronobiology, this roundtable shifts the conversation from algorithmic scores to measurable, cellular safety signals. Join us as we delve into: The Orthosomnia Epidemic: Why waking up to a red recovery score immediately triggers your prefrontal cortex, activates your HPA axis, and flattens your diurnal cortisol curve. The HRV Paradox: Understanding the actual biological markers of Heart Rate Variability and why an algorithmic score doesn't dictate your physical reality. The Cell Danger Response: How the body is only able to sleep when it feels safe, and why the ultimate "detox" might just be a sleep divorce. Your "Do This on Monday" Protocol: Dr. Ted's clinical sleep anchoring technique, and why prioritizing sleep as the first activity of your day changes your entire circadian rhythm. Precision Cellular Nutrients: The clinical difference between taking generic sedatives and utilizing precision magnesium, glycine, and even strategic carbohydrates (like honey) to optimize GABA and melatonin. This episode is for you if: You are experiencing worsening sleep anxiety and chronic insomnia despite meticulously tracking your data every night. You want to learn how to test your cellular metabolomics for brain inflammation instead of relying on a generic smartwatch algorithm. You want to understand how your unique chronobiology dictates your sympathetic and parasympathetic balance. You can also find this episode on… YouTube: https://youtu.be/n71oG96M1Ek Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, the core faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz) tackles one of the most misunderstood topics in modern nutrition: fiber. Moving past the mainstream trend of "fiber-maxing," the team breaks down the actual biochemical realities of how different forms of fiber interact with your unique gut microbiome. From the surprising hormonal impacts of over-consuming fiber to the rise of localized conditions, this roundtable shifts the conversation from generic dietary rules to precise, measurable, cellular data. Join us as we delve into: The Classification of Fiber: Understanding the biological differences between soluble fiber (which breaks down into calories) and insoluble fiber (which adds bulk to stool). The Fiber Maxing Trap: Why forcing massive amounts of psyllium husk, acacia powder, and green drinks can aggravate conditions like Small Intestinal Bacterial Overgrowth (SIBO) and IBS. The Estrogen Heist: The hidden clinical correlation between high-fiber diets (60g+ per day) and the cessation of menstruation (amenorrhea) in female athletes. Short-Chain Fatty Acids (SCFAs): The crucial roles of propionate, acetate, and butyrate as genetic signalers and the primary fuel source for your large intestine. The Gut as an Immune Organ: Why managing the "gut-associated lymphoid tissue" (GALT) forms the basis of roughly 80% of human immune system function. This episode is for you if: You are experiencing worsening gas, bloating, and discomfort despite eating a "clean, high-fiber" vegetarian or whole-food diet. You want to learn how to test your stool for real-time butyrate levels instead of relying on generic probiotic protocols. You want to understand how your unique gut ecosystem mirrors a complex, balancing rainforest. You can also find this episode on… YouTube: Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz reunite in person in Washington, D.C.. Moving away from traditional classifications of illness, the team breaks down a powerful paradigm shift: chronic disease and aging are not separate processes—chronic disease is aging. Drawing from the pioneering frameworks of biogerontologist Aubrey de Grey and the SENS Research Foundation, they discuss how flawed metabolism inherently accumulates structural damage long before a clinical diagnosis ever appears. Join us as we delve into: •The Metabolism Flaw: How the very process keeping us alive produces reactive oxygen species and damage that eventually leads to tissue breakdown and pathology. •Reclassifying Disease: Moving past the old congenital vs. infectious vs. chronic model to target metabolism directly. •The $30,000 Stem Cell Mistake: Why dropping thousands on mesenchymal stem cells (MSCs) or exosomes is a waste of money if your body is trapped in a cellular defense posture. •The Cell Danger Response (CDR): Understanding Robert Naviaux's work on how ancient defense mechanisms shut down growth and repair under stress. •Morbidity Compression: Shifting your biology back to your optimal 21-to-30-year-old baseline to maximize healthspan and ensure you live vibrant before a rapid, peaceful end. This episode is for you if: •You want to understand why biohacking shortcuts like stem cells require metabolic priming to actually work. •You are tired of "normal" lab ranges meant for a sick population and want true, age-optimized biomarkers. •You want to stop guessing what vitamins or antioxidants your body needs and start measuring your exact metabolomic fingerprint. You can also find this episode on… YouTube: https://youtu.be/DygsezbmZxM Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty (Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers) dive deep into the unseen world inside your stomach. Moving beyond simple probiotics, they discuss the gut as a "post-natal organ" and explore how the trillions of microbes inside you actually dictate your cravings, your mood, and your immune system.
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the science and clinical application of creatine. Moving beyond its reputation as just a performance supplement for "gym bros," Boomer Anderson, Dr. Scott Sherr, Dr. Allen Bookatz, and Dr. Ted Achacoso break down how creatine functions as a critical cellular battery buffer. Join us as we delve into: How creatine bypasses the "methylation tax" by saving the body from depleting SAMe reserves to produce energy. Why muscle is a metabolic determinant of resilience and not just a cosmetic feature. The evolutionary mismatch that increases our cellular energy demands due to a highly sympathetic, stressed lifestyle. The role of creatine in brain health is particularly important for supporting working memory, mitigating cognitive fatigue, and protecting against excitotoxicity. This episode is for you if: You are curious about how to support your body's cellular energy and mitochondrial function. You follow a vegetarian or plant-based diet and want to understand your specific creatine supplementation needs. You want to understand the difference between maintaining muscle for aesthetic reasons versus metabolic health. You are looking for strategies to mitigate mental fatigue and sleep deprivation. You can also find this episode on... YouTube: https://youtu.be/R4x9tu56FXg Find more from Health Optimization Medicine and Practice (HOMeHOPe):Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions:Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the HOMe Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz explore a foundational principle of Health Optimization Medicine: What's toxic to the cell is toxic to every organ. Through real clinical cases — including mercury toxicity, arsenic exposure, and environmental toxin accumulation — the team reveals how modern medicine often misses the root cause of disease by focusing on isolated organ systems instead of cellular function. From chronic low-level toxin exposure to acute breakdown events, this episode highlights how toxins disrupt mitochondrial energy production, leading to widespread dysfunction across the body. Most importantly, the conversation emphasizes the role of metabolomics in identifying these hidden stressors early — before they manifest as disease. Join us as we delve into: • Why toxins affect every organ through the cell • A real case of mercury toxicity missed by multiple specialists • How chronic exposure becomes acute illness • Why traditional medicine misses root causes • The role of mitochondria in energy production and health • How metabolomics detects early toxicity and dysfunction This episode is for you if: • You want to understand the root cause of chronic illness • You're exposed to environmental toxins (food, water, air) • You're interested in preventative and optimization-based medicine • You want to take a proactive approach to long-term health You can also find this episode on…Youtube: https://youtu.be/CMhFC5IUKl0 Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Ted Achacoso, Dr. Scott Sherr, and Jodi Duval explore mental health through the lens of health optimization medicine. Rather than viewing mental health as a set of diagnoses, the conversation reframes it as a function of cellular health — where brain function is driven by mitochondrial performance, inflammation, nutrient status, and environmental inputs. From neurotransmitter imbalances to brain inflammation and the gut-brain-microbiome axis, this episode breaks down how modern stressors, lifestyle, and environment impact mental health at the cellular level. Most importantly, the team explains why true mental health optimization must begin with optimizing the health of the cell. Join us as we delve into: • Why mental health should be viewed at the cellular level • The role of mitochondria in brain energy and signaling • Brain inflammation and its impact on mood and cognition • The gut-brain-microbiome axis and neurotransmitter production • Why stress, sleep, and environment drive mental health outcomes This episode is for you if: • You struggle with brain fog, anxiety, or low mood • You want a deeper, root-cause understanding of mental health • You're a practitioner looking beyond traditional psychiatry • You want to optimize cognitive performance and resilience You can also find this episode on…YouTube: https://youtu.be/5xqAzkMUpBs Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Dr. Ted Achacoso, and Jodi Duval as they break down one of the most important frameworks in Health Optimization Medicine — the Cell Danger Response (CDR). Originally developed by Dr. Robert Naviaux, the Cell Danger Response explains how cells respond to threat, adapt for survival, and either resolve or become "stuck" — leading to chronic disease. This episode walks through the three stages of the CDR, how mitochondria act as both sensors and signaling hubs, and why many modern conditions — from inflammation to chronic illness — are actually stalled healing processes. Most importantly, the team explains how clinicians and individuals can identify where the body is "stuck" and what to do (and NOT do) to support proper resolution. Join us as we delve into: What the Cell Danger Response (CDR) is and why it matters The 3 stages: defense, repair, and resolution How mitochondria act as sensors — not just energy producers Why inflammation is a protective response, not the problem How chronic disease reflects a "stalled" healing process This episode is for you if: You're dealing with chronic inflammation or unresolved health issues You want to understand the root cause of disease beyond symptoms You're a practitioner looking for a systems-based framework You want to optimize health by working with your biology, not against it You can also find this episode on… YouTube: https://youtu.be/NWEq32hlZrE Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval as they explore chronobiology — and how modern life is disrupting the body's natural rhythms. From jet lag and shift work to late-night scrolling and irregular meals, the conversation dives into what Dr. Ted calls "circadian pollution" — the mismatch between our biology and the environments we've created. More importantly, the team breaks down simple, powerful tools to re-entrain your body clock using light, food timing, and movement — all foundational principles in Health Optimization Medicine. Join us as we delve into: What chronobiological re-entrainment actually means The difference between the brain clock and organ clocks How light, food, and movement act as biological time signals Why late-night eating creates "metabolic jet lag" How modern life creates circadian disruption This episode is for you if: You struggle with sleep, fatigue, or inconsistent energy You travel frequently or work irregular hours You want to optimize your circadian rhythm naturally You're looking for simple, zero-cost ways to improve health You can also find this episode on… YouTube: https://youtu.be/WcheAJNzq2k Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Jodi Duval, Dr. Allen Bookatz, and Dr. Ted Achacoso as they explore the future of clinical intelligence — and why medicine must move beyond single biomarkers to understanding networks within the body. Rather than chasing isolated lab values like glucose, cholesterol, or testosterone, the conversation shifts toward a systems-based approach — where every biomarker is part of a dynamic network of relationships. From metabolomics to hormone balance, this episode explains why optimizing health requires understanding how different systems interact, adapt, and influence each other in real time. Join us as we delve into: Why single biomarkers are only "nodes" in a larger biological network The concept of nodes and edges in human physiology How glucose, thyroid, and metabolic systems are interconnected Why cholesterol, inflammation, and B vitamins must be viewed together The risks of optimizing one biomarker (like testosterone) in isolation This episode is for you if: You've been told to "fix" a single lab value but still feel off You want to understand your lab results in a deeper, systems-based way You're a practitioner looking to move beyond reductionist medicine You're interested in metabolomics and the future of health optimization You can also find this episode on… Youtube: https://youtu.be/CMbdZEnnuGo Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026:https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://www.homehope.org/ Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://www.troscriptions.com/
In this episode of the Health Optimization Medicine Podcast, join Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval as they explore the hidden cost of convenience and comfort in modern life. From ultra-processed foods and low-fiber diets to sedentary lifestyles and technology-driven comfort, the conversation dives into how convenience is quietly reshaping our biology. The HOMeHOPe Faculty explains why small daily habits — like eating whole foods, moving regularly, and embracing mild discomfort — are essential for maintaining cellular health and resilience. Rather than trying to "hack" health with quick fixes, the discussion emphasizes consistent lifestyle behaviors that support the microbiome, metabolic function, and long-term health optimization. Join us as we delve into: • Why fiber is the fastest disappearing macronutrient in modern diets • The role of gut microbiota and short-chain fatty acids in health • Why habits like sleep, eating, and exercise cannot be "banked" • The physiological consequences of ultra-convenient lifestyles • Practical ways to introduce beneficial stress back into daily life This episode is for you if: • You want to understand how convenience affects human physiology • You're interested in the role of fiber and gut health in disease prevention • You want practical ways to improve resilience and metabolic health • You're curious about the philosophy behind Health Optimization Medicine You can also find this episode on… YouTube: https://youtu.be/6wLPUuLQgcY Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://www.homehope.org/ Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://www.troscriptions.com/
Today, I'm joined by the incomparable Dr. Ted Achacoso—a true pioneer in shifting healthcare from "what's wrong with you" to "what's right with you." Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can't ignore, and how something as simple as a toxicity panel can completely change your health trajectory. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Science, laughter, and Dr. Ted's background ... 00:00:38 Early curiosity, accelerated medical pathway ... 00:07:20 Reframing healthcare: from disease to wellness ... 00:14:04 Cell danger response and importance of metabolomics ...00:16:15 Case study: toxicity panel as diagnostic game-changer ... 00:35:17 Patient motivation and behavioral change ... 00:44:20 Vitamin D: its underestimated power and role ... 00:51:12 Vitamin D paradox, genetics, and medication effects ... 01:00:34 Daily longevity habits and mindset ... 01:22:03 Longevity in one word: balance ... 01:33:05 Home Hope resources and closing ... 01:35:20 Our Amazing Sponsors: Tro Mune by Troscriptions - Cold season doesn't have to take you out. I use Tro Mune—a nightly buccal troche with 75 mg cordycepin—to build immune resilience while I sleep. Take ½–1 before bed, and use it before you get sick or right when you feel it. Troscriptions.com, use NAT10, and get 10% off your first order. Digestive Bitters by Just Thrive - One capsule before eating helps your body absorb more nutrients, ease digestion, and leave you feeling light instead of weighed down. Head over to Justthrivehealth.com/discount/NAT and use code NAT20 for 20% off. Tranq Dart by Wizard Sciences - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. I take it about 30 minutes before bed, and it helps my body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off. Sleep smarter, not harder. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
In this episode of the Smarter Not Harder Podcast, the HOMeHOPe Faculty — Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz — reunite for a timely and insightful roundtable on play, presence, and practitioner power in the age of AI. From microdosing in medicine to using ChatGPT in clinical care, this conversation explores how fun, flow, and forward-thinking frameworks can reinvent healthcare from the inside out. Join us as we delve into: • How "play" transforms clinical performance, creativity, and resilience • The promise and pitfalls of AI like ChatGPT and Gemini in modern medicine • HOMeHOPe's model of proactive care — and why health optimization starts before symptoms • From burnout to breakthrough: how clinicians can reclaim joy and curiosity in practice This episode is for you if: • You're a clinician feeling trapped between protocols and possibility • You want to integrate fun, flow, and fulfillment into your professional life • You're curious about AI in healthcare — and how to use it responsibly • You're done with sick-care and ready to optimize health before disease strikes You can also find this episode on… Youtube: https://www.youtube.com/watch?v=gzgJ81OZ2lM Find more from Smarter Not Harder: Website: Smarter Not Harder Podcast Instagram: https://instagram.com/troscriptions/ HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org/ Get 10% Off your Troscriptions order with code POD10 at https://troscriptions.comGet daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, Boomer Anderson, Dr. Scott Sherr, Dr. Ted Achacoso, Jodi Duval, and Dr. Allen Bookatz come together for a powerful HOMeHOPe Faculty roundtable exploring the gut — not just as a digestive organ, but as the root of mood, metabolism, immunity, and long-term vitality. This conversation blends systems biology, ancient medicine, and cutting-edge diagnostics to give you a radically holistic view of gut health and what it really takes to heal from within. Join us as we delve into: • How gut health influences brain function, mood, and clarity • The role of trauma and stress in gut dysfunction • Stool testing, diagnostics, and when "more data" isn't better • Probiotics, fiber, and the personalized approach to microbiome support This episode is for you if: • You're chasing mental clarity or performance through your gut • You've tried "gut protocols" but still feel off • You want a clinical, systems-based approach to GI health • You're ready to go beyond buzzwords and into the real science of the microbiome You can also find this episode on… YouTube: https://youtu.be/G4BHp6d9T00 Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast?utm_source=youtube&utm_medium=video&utm_campaign=snh_podcast_homehope_2025_10_09&utm_content=weekly_episode Instagram: https://instagram.com/troscriptions/ Get 10% Off your purchase of the Gut-Immune System Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions order with code POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, the HOMeHOPe Faculty — Dr. Ted Achacoso, Dr. Scott Sherr, Jodi Duval, and Dr. Allen Bookatz — gather for an eye-opening and deeply personal roundtable on the real impact of small lifestyle changes. From hydration to circadian biology, sleep divorces to grayscale screens, this episode breaks down the science behind everyday habits that create extraordinary transformation. Join us as we delve into: Why hydration timing may matter more than hydration amount How “sleep divorces” saved marriages and improved HRV When working out less leads to more energy and fat loss The grayscale phone hack that reclaims your dopamine and your sleep This episode is for you if: You think lifestyle change has to be hard, expensive, or dramatic You're curious why patients resist the simplest habits — and how to get them to comply You've tried “healthy” changes and wondered why they didn't work You're ready to fall in love with feeling well — and want to help others do the same You can also find this episode on…YouTube: https://youtu.be/KVRtjQ9pCgE Find more from Smarter Not Harder:Website: https://troscriptions.com/pages/podcast Instagram: https://instagram.com/troscriptions Get 10% Off your purchase of the Metabolomics Module by using *PODCAST10* at https://homehope.org Get 10% Off your Troscriptions purchase by using *POD10* at https://troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
Discover the latest science and proven strategies I've personally tested to finally conquer jet lag so you can adapt faster, boost your energy, and arrive clear-minded and ready to perform.New episodes every Friday!Episode brought to you by: Alive Waters (Code: ASHLEY)Episode brought to you by: ARAZA BeautyHyperlinked show notes at www.ashleydeeley.com/jetlag1:06: Fluoride is more electronegative than oxygen (this means, do not drink tap water before, during, or after your flight!)1:34: Temperature minimum (brought to you by Andrew Huberman's episode on jetlag)3:00: Theralux (not available on Amazon)3:30: Avoid sugar, alcohol, and carbs three days before a flight and during the flight3:46: Non-negotiables: wearing a hat and blue blockers5:47: Fast on all domestic flights (fast as long you can on international flights)6:14: Echo hydrogen water bottle 6:31: Quinton minerals - Quintessential 3.3 Sachets7:03: Never consume LMNT or Liquid IV8:00: Move every hour on the hour, plus drink 8-10 oz of water every hour on the hour (except when sleeping)8:41: Dr Jack Kruse says "here's how to stay grounded while flying"9:21: My VivaRays blue blockers10:14: Don't wear contact lenses while traveling10:45: Don't use air vent from above (as it's mixed with engine air)11:17: Matthew Walker says: sleep first when you get on a plane, not last12:03: Change settings on your device to emit an orange or red hue To set your iPhone screen to red, navigate to Settings > Accessibility > Display & Text Size > Color Filters, turn on Color Filters, select Color Tint, then slide Intensity and Hue all the way to the right14:00: Melatonin from Synchronicity Health14:16: Melatonin suppository (called the Sandman from Mitozen)15:50: Calm your nervous system (parasympathetic state) for travel16:09: 4-7-8 breathing by Dr. Andrew Wiel16:46: NuCalm (my FAVORITE jet lag hack)18:21: Apollo Neuro device19:27: KAATSU device20:22: VieLight redlight device Supplements for travel:21:51: Vitamin B622:09: 5-HTP22:21: Glycine22:46: MyVitalC23:43: Organic Astaxanthin24:04: NAD+ and Glutathione bonus — Geroge Gavin: Founder of Synchronicity Health, episode 9325:58: Vitamin C from Cymbiotika / Vitamin C from BodyBio26:05: NAC26:06: CoQ10 26:09: Fish oil (THE ONLY fish oil I recommend!!!) 26:50: Glucosamine26:59: Methylene blue28:12: Dr. Tom Rogers, episode 71 on methylene blue28:35: CBD suppository (save 20% on first order with this link) 29:12: Dr. Ted Achacoso (his interview with Ben Greenfield - jet lag: start at 53:20 - Rolls Royce for hacking jet lag - uses Human Growth Hormone, thyroid hormone, testosterone at 50mg, digestive enzymes, & EPO)29:19: Portable oxygen concentrator, according to the FAA, here the approved portable oxygen concentrator brands (many require a prescription)These are apparently best brands:Inogen One (prescription required) Sequel Eclipse (prescription required) Airsep Lifestyle (or buy here too / or buy here)31:30: Progesterone (to assist females with sleep, males need a MUCH lower does) 31:49: Estrogen (for women with achy joints)31:58: DHEA 32:32: TimeShifter app32:56: DSIP peptide (Delta Sleep Inducing Peptide)33:27: Grounding/Earthing upon arrival34:19: Wear silicone ear plugs and an eye mask34:38: Travel neck pillowComprehensive Supplement Guide:Stimulant:Methylene BlueNAD+MyVitalC (ESS60)Anytime:Quinton mineralsAstaxanthinGlutathioneCoQ10Vitamin CNACFish OilGlucosamineDHEAEstrogen (for women)Sleep Aid:MelatoninCBD suppository5-HTPGlycineVitamin B6Progesterone (for women)Where to find Ashley Deeley:WebsiteInstagramFacebookYouTubehello@ashleydeeley.com
In this episode of the Smarter Not Harder Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the quirky and often embarrassing health practices they've experimented with in the pursuit of optimization. From unusual bedtime routines to unconventional supplement regimens, the Faculty share candid stories that highlight both the humor and challenges of living a biohacker's lifestyle. Join us as we delve into: The surprising rituals that embarrass family and friends What extreme supplement use taught Dr. Ted about metabolomics Sun exposure experiments gone wrong (and right) How personal quirks led to the development of real health optimization frameworks This episode is for you if: You're curious about the behind-the-scenes realities of health hackers You've ever felt “weird” about your wellness practices You want to learn from the Faculty's successes and missteps You're interested in how experimentation leads to better health frameworks You can also find this episode on… YouTube: https://youtu.be/WbWc1Rtmo3o Find more from Smarter Not Harder: Website: https://www.troscriptions.com/pages/podcast Instagram: https://www.instagram.com/troscriptions HOMeHOPe Symposium: https://homehope.org/homehope-symposium Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, Dr. Ted Achacoso, Dr. Jup Kuipers, Dr. Scott Sherr, Dr. Allen Bookatz, Jodi Duval, and Boomer Anderson come together for a HOMeHOPe Faculty roundtable exploring the beliefs they held about health and medicine a decade ago—and what they've learned since. With a mix of personal anecdotes, clinical shifts, and humorous hindsight, the team unpacks how science, biohacking, and real-world experience have reshaped their perspectives. Join us as we delve into: • Why saturated fat, vitamin D megadosing, and antioxidants aren't always what they seem • The myth of genetic determinism and the rise of epigenetics • Raw veganism, brisket awakenings, and detox smoothie fails • Bulletproof coffee, microbiota, and the lessons of quantified self experiments This episode is for you if: • You believed the hype of 2015 wellness trends • You're curious how leading health professionals think differently now • You want practical insight into what *actually* works in functional health • You appreciate candid, vulnerable stories from elite health experts You can also find this episode on… YouTube: https://youtu.be/2xQDt_-sSmc Find more from Smarter Not Harder: Website: https://www.troscriptions.com/pages/podcast Instagram: https://www.instagram.com/troscriptions HOMeHOPe Symposium: https://homehope.org/homehope-symposium Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this live round-table episode of the Smarter Not Harder Podcast, Boomer Anderson sits down with Dr. Scott Sherr, Dr. Ted Achacoso, Jodi Duval, and Dr. Allen Bookatz to explore how syncing your biology with circadian rhythms may be more powerful than any 3-day fast. From defining ultradian and infradian rhythms to tackling jet lag, hormone timing, and shift work, the team shares clinical stories and practical tactics you can use to reset your internal clock and optimize recovery, metabolism, and mood. Join us as we delve into: Why circadian rhythm alignment may be more effective than prolonged fasting The science of sleep anchoring, Zeitgebers, and peripheral clocks How your sleep, hormones, and hunger cues are dictated by light and food timing Simple tools to reset your rhythms—even after sleep debt or night shifts This episode is for you if: You're struggling with brain fog, low energy, or poor sleep despite “getting 8 hours” You want to learn practical tools for syncing your biology to light and food You're a night shift worker, traveler, or new parent trying to reset your rhythm You believe that healthspan starts with consistent daily habits—not heroic interventions You can also find this episode on… YouTube: https://youtu.be/AC_j9ZLHUnM Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at homehope.org Get 10% Off your Troscriptions order by using POD10 at troscriptions.com Get daily insights from the hosts by following @troscriptions on Instagram.
In this episode & live round-table of the Smarter Not Harder Podcast, Boomer Anderson sits down with Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz to unpack the shift from “sick-care” to genuine health-care. Drawing on stories from primary care, the ER, and longevity practice, they explain how the Health Optimization Medicine (HOMe) model uses metabolomics, gut testing, and evolutionary biology to keep you thriving—long before disease strikes. Join us as we delve into: Why traditional, disease-centered medicine struggles with chronic conditions The HOMeHOPe framework and its focus on cellular & holobiome health Real-world cases that reveal the cost of treating symptoms instead of root causes How medical education must evolve to create a true “standard of care for health” This episode is for you if: You're frustrated by the limits of conventional check-ups You want practical ways to apply lab data beyond “normal” reference ranges You're a practitioner ready to integrate proactive, personalized strategies You believe healthspan—not just lifespan—should be the goal You can also find this episode on…YouTube: https://youtu.be/EMDOXr43Xg8 Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at homehope.org Get 10% Off your Troscriptions order by using POD10 at troscriptions.com Get daily insights from the hosts by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, Jodi Duval leads a powerful conversation with Dr. Ted Achacoso, Dr. Scott Sherr, and Dr. Allen Bookatz about burnout in clinical practice—and how to actually prevent it. From saying no to draining patients to finding joy in curiosity and community, the team shares practical tools for sustaining a long, fulfilling career in medicine. Join us as we delve into: Why it's okay (and sometimes necessary) to fire patients Daily rituals and mindset shifts that protect your energy How practitioner community can prevent isolation and overwhelm Curiosity, compassion, and fun as the ultimate burnout antidotes This episode is for you if: You're a health practitioner feeling stretched thin You struggle with boundaries or people-pleasing in your practice You want to build a career that supports your life—not consumes it You're curious how other experts stay grounded and energized You can also find this episode on... YouTube: https://youtu.be/D-Xa2y5kL10 Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, the Troscriptions and HOMeHOPe faculty get personal. Dr. Scott Sherr, Dr. Ted Achacoso, and Jodi Duval go behind the curtain on what they're actually taking, testing, and tossing when it comes to supplements. From methylene blue pessaries to kratom gummies, designer peptides to custom troches—this roundtable reveals how experienced clinicians approach their own protocols, and the often messy process of self-experimentation. Join us as we delve into: The real story behind what's in their supplement drawers How the team thinks about sourcing, stacking, and individual response Why clinical integrity requires “I tried it first” energy How experiments sometimes fail—and why that matters This episode is for you if: You want to see how the experts actually apply what they preach You're supplement curious and tired of cookie-cutter stacks You're interested in self-experimentation with clinical guardrails You like your protocols with a side of honesty and humor You can also find this episode on… YouTube: https://youtu.be/SqiPu8rhH80 Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, we dive into the outrageous, unexpected, and sometimes uncomfortable experiments our hosts have tried in the name of health optimization. From gallbladder flushes and vitamin D megadosing to powerlifting with a colonic and hiking mountains while microdosing, this episode is full of real (and ridiculous) stories. Boomer Anderson, Dr. Scott Sherr, Dr. Ted Achacoso, Jodi Duval, and Dr. Allen Bookatz share the protocols they've tested so you don't have to — and what they actually learned from pushing the limits. Join us as we delve into: Gallbladder cleanses, colonics, and detox stories gone wrong High-altitude hypoxia and the limits of willpower Hormone overloads, supplement misadventures, and questionable decisions What happens when doctors test their own advice This episode is for you if: You've ever wondered what not to do in the name of health You enjoy honest, hilarious stories from doctors and experts who walk the talk You're curious about the weirder side of biohacking You want to laugh while learning what actually works (and what definitely doesn't) You can also find this episode on… YouTube: https://youtu.be/1MeVFueqxJg Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at homehope.org Get 10% Off your Troscriptions order by using POD10 at troscriptions.com Get daily insights from the hosts by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, Boomer Anderson, Dr. Scott Sherr, and Dr. Ted Achacoso dive deep into the topic of hydration, debunking common myths and offering practical tips. They clarify the effects of caffeine and alcohol as diuretics and discuss the misconception about clear urine indicating proper hydration. They explore the evolutionary aspects of water's role in biology and provide specific recommendations for daily water intake, emphasizing the importance of a little salt and possibly sugar for optimal hydration. The conversation also covers various methods for ensuring clean and effective hydration, including filtration systems and the importance of not drinking calories. Join us as we delve into:- The physiology of hydration – Where water actually goes in your body - Diuretic myths debunked – Coffee, alcohol and coconut water exposed - Electrolyte optimization – How to make your own medical-grade hydration solution - Travel hydration protocols – Why you're dehydrating faster than you think This episode is for you if:- You want to optimize cellular hydration for peak performance - You're tired of contradictory advice about water intake - You've wondered if structured water systems are worth the investment - You need science-backed hydration hacks for travel or workouts You can also find this episode on…YouTube: https://youtu.be/s_s3lRNwaqA Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
Dr. Achacoso is double board certified in Nutritional Medicine and Interventional Endocrinology and is a world-renowned anti-aging, hormone, and mitochondrial expert. He also happens to be one of the most intelligent people alive (this isn't an exaggeration—he's known for having one of the highest IQ scores ever recorded!). So, while our discussion is a bit geeky and in-depth, it's truly worth your time…especially as we condense Dr. Achacoso's brilliance into practical steps for optimizing your mitochondria and beating fatigue! This podcast was first released in May 2018
In this episode of the Smarter Not Harder Podcast, the HOMeHOPe team recaps the key health trends and significant moments of 2024. Featuring Jodi Duval, Dr. Ted Achacoso, Boomer Anderson, and Dr. Scott Sherr, the discussion covers complex adaptive systems, metabolomics, the FDA's stance on MDMA, and the rise and challenges of GLP-1s in obesity management. They also delve into the evolving mental health landscape, the role of GABA, and the advancements in AI. Join us as we delve into: + The evolving world of psychedelics + Health and technology trends on the rise + Building a global community of health professionals + The crossroads of disease treatment & health optimization This episode is for you if: - You're fascinated by the role of AI in advancing healthcare - You're intrigued by the evolution of mental health discourse post-COVID - You're keen to explore metabolomics and health optimization medicine - You're interested in understanding the impact of psychedelics in medical practice You can also find this episode on… YouTube: https://youtu.be/UkwDpJ-ztJQ Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
Ultraculture With Jason Louv. Drted Assemble Logic 3.
In this episode of the Smarter Not Harder Podcast, Dr. Ted discusses the profound connection between your gut and your brain. He reveals how the health of your gut microbiome can directly influence your mood, mental clarity, and even your risk of neurodegenerative diseases. *Join us as we delve into:* + The gut as a "second brain": Dr. Ted explains how your gut has its own nervous system, produces neurotransmitters, and communicates with your brain. + Gut dysbiosis and its consequences: Learn how an imbalanced gut microbiome can lead to inflammation, brain fog, and contribute to conditions like anxiety and depression. + Leaky gut and neuroinflammation: Discover the connection between a compromised gut lining and inflammation throughout the body, including the brain. + Optimizing gut health for brain health: Dr. Ted shares practical tips, dietary changes, and innovative therapies to improve your gut microbiome and support optimal brain function. This episode is for you if: - You struggle with mood imbalances, anxiety, or brain fog. - You're interested in the cutting-edge science of the gut-brain axis. - You want natural, proactive strategies to optimize your mental and physical health. - Get ready to learn how the health of your gut can unlock a healthier, happier you! *You can also find this episode on…* Youtube: https://youtu.be/NXcOFA8jPN8 *Find more from Dr. Ted Achacoso:* Facebook: facebook.com/drtedachacoso/ Instagram: instagram.com/tedace/ *Learn more about Smarter Not Harder:* Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this weeks episode of "Pushing the Limits" I interview one of my idols in the world of health optimisation medicine, hyperbaric oxygen therapy and cellular health Dr Scott Sherr, a repeat guest to the show. In this episode we go deep into the benefits of: Hyperbaric Oxygen Therapy, what it does, the pathways it affects from: Stem cell production to inflammation downregulation to lymphatic support to angiogenesis We discuss the health issues this powerful therapy can benefit We discuss protocols, the different types of chambers and pressures and how to build a foundational health protocol around the person's treatment. We also do a deep dive into one of my favorite research subjects at the moment - Methylene Blue and it's myriad of effects in the body and how it may help support: energy production by bypassing the first two complexes in the electron transport chain in the mitochondria what ailments it may help with from alzheimers and cognitive declines to TBI to UTI's to depression to athletic performance to carbon monoxide poisoning, mitochondrial dysfunction to malaria and it's use as the world's first antibiotic and more We dive into it's long history and where the current science stands on this exciting compound. We look at how it has a biphasic response curve and how it works as both an antioxidant and pro oxidant and why pharmaceutical grade is crucial. Then we dive into the GABA system and how it affects recovery and sleep and formulations that support this system besides taking actual GABA that alone doesn't cross into the blood brain barrier. We also discuss Dr Scott's and Dr Ted Achacoso's non profit educational arm https://homehope.org/ where doctors and practitioners can advance their learning in the holobiont. They provide the framework for doctors and health care practitioners to learn how to optimize their clients' health, rather than treat disease. Health Optimization Medicine (HOMe) was founded in the Philippines by Dr. Theodore Achacoso after realizing that illness medicine, in which he is trained and excels as an interventional neuroradiologist and pharmacologist, was reactive, interventional, and could benefit from an entirely different approach: one that optimized health rather than treated disease. Over several years, he became an expert in the intricacies and power of metabolomic, gut, and hormone optimization, along with the additional pillars of what became HOMe. How to find Dr Scott and his work You can visit Dr Scott's hyperbaric oxygen therapy clinics at https://www.hyperbaricmedicalsolutions.com Visit his supplement company Troscriptions where they have formulations including methylene Blue among others here You can use the code LISA His hyperbaric educational company One Base Health here Transcription products from Dr Scotts company are not available for New Zealanders unfortunately however if you are interested in getting methylene Blue please reach out to us directly at support@lisatamati.com BIO Dr. Scott Sherr is a Board Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe) and a specialist in Hyperbaric Oxygen Therapy (HBOT). He graduated Summa Cum Laude from UCLA as an undergraduate and Magna Cum Laude with Alpha Omega Alpha distinction from the University of Maryland Medical School. Dr. Scott is the founder of HOMe-SF, the first HOMe clinic in the United States, and is also the Chief Operating Officer of Health Optimization Medicine and Practice (HOMe/HOPe)–USA, a nonprofit education company. The HOMe/HOPe essential certification (plus two advanced modules in Peptides and Cannabis) teaches doctors and healthcare practitioners how to detect and correct the root causes of health, not disease. In addition, Dr. Scott is also COO of Smarter Not Harder, the for-profit arm of HOMe/HOPe. SNH is the company behind Troscriptions, a line of buccal troches that are Democratizing Enlightenment by addressing the bottlenecks along the path to optimal health. They have several products on the market including Blue Cannatine, Just Blue, Tro Calm, and Tro Zzz Dr. Scott's clinical practice includes HOMe as its foundation plus an integrative approach to hyperbaric oxygen therapy that includes cutting-edge and dynamic HBOT protocols, comprehensive laboratory testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new and ancient), and more. Dr. Scott lives in Louisville, CO with his wife and his 4 children. Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with: Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals Nutristat Omega 3 to 6 status and more Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission. Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to https://www.buymeacoffee.com/LisaT to donate $3 Lisa's Anti-Aging and Longevity Supplements Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world. This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life. Subscribe to our popular Youtube channel with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge" Check them all out at https://shop.lisatamati.com/collections/books Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here: Use code "tamati" at checkout to get a 10% discount on any of their devices. Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38 Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa and team
In this episode of the Smarter Not Harder Podcast, Dr. Ted Achacoso, a pioneer in Health Optimization Medicine and Practice (HOMe/HOPe), dives into the revolutionary perspective of health as an active, ongoing process rather than simply the absence of disease. *Join us as we delve into:* + The Cell Danger Response (CDR): How it drives our body's reactions to stress, both internal and external. + Multi-omics approaches: The tools (like clinical metabolomics) that uncover imbalances before major diseases manifest. + Evolutionary medicine: Understanding our health needs in the modern world based on how our bodies evolved. + The importance of balance: Fine-tuning nutrition, inflammation, and other key systems for true health, not just feeling "not sick" This episode is for you if: - You're interested in proactive approaches to health and longevity. - You want to understand the cutting-edge science behind optimizing your well-being. - You're frustrated with traditional medical approaches that focus solely on treating symptoms. - You're curious about how your environment, diet, and even mindset influence your health at the cellular level.
In this episode of the Smarter Not Harder Podcast, host Boomer Anderson is joined by guest Dr. Ted Achacoso to give one-cent solutions to life's $64,000 questions that include: What is the importance of understanding clinical metabolomics and measuring nutrient levels in the optimization of health, and how does this counter fear-based narratives surrounding multivitamin use and cancer risk? How does viewing health and illness at the right level, and understanding the role of vitamins, minerals, and cofactors in cancer treatment challenge conventional wisdom and contribute to a new perspective on health and wellness? How can a shift in mindset from the notion that supplements don't work to recognizing their essential role for overall health, as well as the concept of the body as a self-regulating ecosystem, encourage a fresh, informed approach to health? What We Discuss: (0:04:03) - The need to understand clinical metabolomics levels for better health decisions (0:18:21) - The survival instinct of cells and their link to cancer, and the use of vitamins and minerals in cancer treatment (0:22:44) - The surprising truth of studies, emphasizing the role of education and the necessity to understand how studies work (0:29:23) - Health optimization medicine and how body wisdom can be used for optimal health, and the importance of listening to our bodies and understanding individual needs through clinical metabolomics Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, host Boomer Anderson is joined by Dr. Ted Achacoso and Dr. Scott Sher to give one-cent solutions to life's $64,000 questions that include: Why is sleep essential for both our physical and mental health and what techniques can be employed to optimize sleep quality? How to improve sleep quality and which supplements help? What changes in lifestyle can cause alterations in an individual's chronotype and sleep patterns? What We Discuss: (0:02:00) - Why sleep is vital for our physical and mental health, and the consequences of sleep deprivation, and the significance of REM sleep and a proper sleep schedule. (0:14:09) - Sleep optimization techniques, the role of metabolomic data in health enhancement, and the impact of light, water, and magnetism on synchronizing our circadian rhythms. Dr. Ted's sleep anchoring technique. (0:25:01) - Sleep optimization methods like the role of blackout blinds, temperature control, and ways to deal with difficult partners. Plus the potential of supplements like melatonin to address sleep issues. (0:32:53) - Strategies to optimize sleep, the role of exercise, and the use of supplements like melatonin and magnolol bark. (0:44:02) - How to improve sleep and manage stress effectively, including stopping work before bed, using supplements to improve sleep, and understanding Dr. Bruce's chronotypes. (0:49:20) - How lifestyle and job changes can affect chronotypes and the importance of recognizing and adjusting to changing sleep needs. Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, host Boomer Anderson is joined by Ted Achacoso and Scott Sher to discuss the first Health Optimization Medicine and Practice symposium, and give one-cent solutions to life's $64,000 questions that include: How does the Health Optimization Medicine (Home Hope) approach use science and technology to detect and correct imbalances in our bodies, and how can it benefit individuals from elite athletes to cancer patients? What is the pivotal role of GABA, cannabinoids, microbiota, and ketones in health optimization? What is the future of health optimization symposiums and how does the concept of community play a significant role in the learning and sharing of knowledge in this field? What We Discuss: 03:00 - Explanation of how Health Optimization Medicine (HomeHope) uses science and technology to detect and correct imbalances in our bodies 06:45 - Discussion on how the Home Hope approach can benefit individuals ranging from elite athletes to cancer patients 12:10 - In-depth talk about the pivotal role of gut health in our overall wellbeing 15:30 - Explanation of how GABA, cannabinoids, and microbiota play a pivot role in health optimization 24:10 - Insights from the Health Optimization Medicine Symposium 33:00 - Predictions for the future of health optimization symposiums 36:50 - Discussion on how the concept of community plays a significant role in the learning and sharing of knowledge in the health optimization field Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, our guest Dr. Jack Kruse joins our host Dr. Ted Achacoso to give one-cent solutions to life's $64,000 questions that include: How has the COVID-19 pandemic influenced the shift towards decentralized medicine and what role does patient informed consent and medical freedom play in this shift? What is the impact of centralized medicine on naturopathic doctors, chiropractors, and Eastern medicine practitioners, and how can this be addressed by decentralized medicine? What are the implications of technology on public health, specifically in terms of electronic health records and how it can potentially undermine or enhance the healthcare system? Dr. Jack Kruse is a neurosurgeon and CEO of Optimized Life, a health and wellness company dedicated to helping patients avoid the healthcare burdens we typically encounter as we age. He is a member of the American Association of Neurological Surgeons, the Congress of Neurologic Surgeons, and Age Management Medicine Group. As a neurosurgeon, Dr. Kruse's research has been published in respected dental and medical journals. What We Discuss: (0:01:21) - Navigating the Future of Healthcare with Decentralized Medicine (0:09:15) - Medical Sovereignty and its Role in Shaping Decentralized Medicine (0:24:31) - Impact of Decentralized Medicine on Modern Healthcare Systems (0:34:16) - The Fallacy of Statins and Proposing a Shift towards Decentralized Medicine (0:42:21) - Implementing a Tripartite System for Efficient Healthcare Administration (0:46:41) - Penalties for Doctors in the Decentralized Medicine Landscape (1:02:35) - Journey into the Core Principles of Decentralized Medicine (1:17:53) - Envisioning the Future of Medicine Through Decentralization (1:32:48) - Evolution of Medical Education in the Era of Decentralized Medicine (1:40:59) - Photosynthesis, Geographical Latitudes, and Potential Extinction Events (1:47:04) - Understanding the Quantum Effects of Light and Psychedelics (1:59:59) - Quantum Coherence and its Role in Mitochondrial Functioning (2:11:59) - Embracing Decentralized Medicine: Advice for a Healthy Life (2:22:01) - A Sneak Peak into the Upcoming Film Depicting Jack's Life and Contributions to Medicine. Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Jack Kruse: Instagram: https://www.instagram.com/drjackkruse Website: https://jackkruse.com/ Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, our guest Dr. Bobby Azarian joins our host Dr. Ted Achacoso to give one-cent solutions to life's $64,000 questions that include: How does the neuroscience of belief and cognitive biases, such as confirmation bias and the Dunning-Kruger effect, impact our resistance to changing beliefs and our approach to epistemic foraging? In what ways can understanding the concept of hierarchical emergence in the universe, and viewing everything from ant colonies to nations as a single organism, contribute to our understanding of consciousness, self-modeling, and mental resilience? How can the exploration of theories such as the Bayesian brain hypothesis, neuroDarwinism, terror management theory, and Cleodynamics enhance our understanding of the human mind, the universe, and the potential for predicting chaotic events? Dr. Robert Azarian (Bobby Azarian) is a science journalist and a cognitive neuroscientist who received his PhD from George Mason University. He has written for publications such as The Atlantic, The New York Times, BBC, Scientific American, Slate, HuffPost, Quartz, and Aeon, and he writes the blog “Mind in the Machine” for Psychology Today. His recent book is called The Romance of Reality: How the Universe Organizes Itself to Create Life, Consciousness, and Cosmic Complexity. What We Discuss: (0:05:15) - Neuroscience of Belief and Epistemic Foraging (0:14:57) - Hierarchical Emergence in the Universe (0:22:36) - Neuro Darwinism and Terror Management Theory (0:29:57) - Predicting Behavior Through Network Analysis (0:38:41) - Bayesian Brain Hypothesis and Psychoplastogens (0:42:53) - Defining Life (0:56:24) - Exploring Consciousness and the Self (1:12:30) - Health Optimization Medicine and Omega Point (1:26:53) - Synthesis of Thermodynamics, Information, Evolution (1:35:10) - Energy and Information in Thermodynamics and Evolution (1:42:48) - Evolutionary Theory and Unifying BVSR (1:51:09) - Evolutionary Cooperation and the Energy Problem (1:59:18) - Living Life Smarter, Not Harder (2:10:30) - Encouraging Reading and Personalized Knowledge Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Bobby Azarian: Twitter: https://twitter.com/bobbyazarian Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, our guest Dr. Kiran Krishnan joins our host Dr. Ted Achacoso to give one-cent solutions to life's $64,000 questions that include: What are the most exciting clinical developments in the field of gut microbiota and probiotic supplementation? How do outer membrane vesicles violate the dogma that bacteria and human cells should not communicate directly? Why is the gut microbiota now considered an organ in the body that is postnatal, or an organ that grows right after birth? Kiran Krishnan is a Research Microbiologist and has been involved in the dietary supplement and nutrition market for the past 17 years. He comes from a strict research background having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa. He left University research to take a position as the U.S. Business Development and Product Development lead for Amano Enzyme, USA. Amano is one of the world's largest suppliers of therapeutic enzymes used in the dietary supplement and pharmaceutical industries in North America. Kiran also established a Clinical Research Organization where he designed and conducted dozens of human clinical trials in human nutrition. What we discuss: (0:00:04) - Gut microbiota and probiotics revolution (0:17:21) - Gut microbiota and organ function (0:25:30) - Bifidobacterium longum's impact on mood (0:31:22) - Gut bacteria and brain development (0:45:55) - Microbiome and covid-19 risk factors (0:51:41) - Inter-kingdom communication and implications (1:12:09) - Probiotics' impact on inflammation and microbiome (1:17:19) - Microbiome analysis in clinical trials (1:24:02) - Microbiome's role in addiction and autoimmunity (1:37:30) - Microbiome functionality and redundancy (1:42:10) - Foundational organisms and future projects (1:55:10) - Advancing phytoceuticals and extraction processes (2:11:47) - Advancements in gut microbiota science Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Kiran Krishnan: Instagram: @kiranbiome Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In this episode of the Smarter Not Harder Podcast, our guest Dr. Ted Achacoso joins our host Dr. Scott Sherr to give one-cent solutions to life's $64,000 questions that include: What is GABA, and why do we need it? How is GABA synthesized? What are some of the conditions and syndromes that are related to GABA deficiency? Dr. Ted is the founding pioneer of Health Optimization Medicine and Practice, a 501(c)3 nonprofit organization dedicated to helping doctors and practitioners learn how to optimize for health rather than treat disease. He is also the founder of Smarter Not Harder Inc, makers of Troscriptions. He went to med school at the age of 18, and is trained in interventional neuroradiology, toxicology and pharmacology. He is also trained in anti-aging medicine, nutritional medicine, and is an expert in hormone balancing. What we discuss: (0:02:14) - Understanding GABA (0:14:21) - GABA receptors and their subtypes (0:24:03) - GABA's role in brain function (0:35:20) - Sleep-inducing substances and their effects (0:41:33) - Health optimization and balanced living Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Ted Achacoso: https://homehope.org Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
Get ready to fill your cups – literally and figuratively – with the knowledge and insight of Shawn Wells and Daniel Solomons, the minds behind UPDATE, an incredible new caffeine alternative which just may have become the official beverage of The Life Stylist podcast. Shawn Wells is known as The World's Greatest Formulator. He's a biochemist and dietician who is nearly 1,000 supplements into his career, using something like 25 unique ingredients patented. He's also a biohacker, himself, and the author of the bestselling book, The Energy Formula. Daniel Solomons is a former investment banker from Sydney, Australia. He moved to New York City to launch UPDATE and change the energy drink market forever. They've spent the last three years working out how to create the best, healthiest possible, energy solution – an evolution to caffeine. If you're feeling energized by the ideas presented in this conversation, shop with 10% off at drinkupdate.com/luke. DISCLAIMER: This podcast is presented for educational and exploratory purposes only. Published content is not intended to be used for diagnosing or treating any illness. Those responsible for this show disclaim responsibility for any possible adverse effects from the use of information presented by Luke or his guests. Please consult with your healthcare provider before using any products referenced. This podcast may contain paid endorsements for products or services. 00:00:07 — Meeting Our Guests & Mapping the Journey • How Shawn became The World's Greatest Formulator • Background work in biochemistry, nutrition, and clinical settings • From conceptualization to commercialization • Caffeine as a $1 trillion market • Other caffeine-focused brands in the space • Testing and experimenting with nootropic ingredients • Incorporating paraxanthine into the formulation • Shawn's personal pain-to-purpose journey • Luke honors Shawn's vulnerability with his own • Radical Redemption & Total Transformation w/ Tah & Kole Whitty #331 • The moment he anchored love in his heart and soul • Daniel's personal journey of opening up to the world • His unique experience with ayahuasca • Letting go of expectation attached to psychedelic journeys • The Condor Approach by Tah Whitty and Kole Whitty • Integration Is Not Optional: Future of Psychedelic Coaching & Humanity's Healing w/ Tah + Kole #442 00:57:56 — Getting the UPDATE: What, Why & How? • Chemistry deep dive – what is paraxanthine? • Shop: Get 10% off at drinkupdate.com/luke • How caffeine metabolizes and why it's important • Why bigger person ≠ bigger dose • Why your sleep is not at risk • Protecting the brain with new neurons • Have both — cleaner energy and better sleep • Is adrenal fatigue real? (Yes) • Biochemical addiction to stress 01:51:42 — Stacking Ingredients for the Ultimate Nootropic • Breaking down some of the stacked ingredients in UPDATE • Myth busting taurine's role in our bodies • Improving the formula for flavor • Luke's raw liver smoothies • What water is used in UPDATE? • Shop: Get 10% off at drinkupdate.com/luke • The natural beauty of green tea's formulation • 5HTP's role in the recipe – a key to swagger • Deploying activated B12 for neurological benefit • DMSO: The Most Suppressed Natural Remedy & Best-Kept Secret in the World? w/ Amandha Vollmer #480 • What is the future vision for UPDATE? • UPDATE as a post-journey recovery stack • Luke asks about paraxanthine and microdosing • Shawn introduces something new: echo dosing More about this episode. Watch on YouTube. THIS SHOW IS BROUGHT TO YOU BY: RHIZAL. RHIZAL's goal is to reconnect you with your feet, and your feet with the Earth. We're crafting grounded, barefoot, natural shoes you'll actually want to wear. Get 10% off your RHIZAL grounded shoes at rhizal.co/luke10. AND… ARMRA. Transform your health starting at its foundation. ARMRA Colostrum™ protects, rebuilds, and strengthens your body's barriers for defense against everyday threats and enhanced vitality. Go to tryarmra.com/LUKE or enter LUKE to get 15% off your first order. AND… ALITURA NATURALS. Your skin is the largest organ and it needs to be treated like another mouth. If you're as careful about what you put on your skin as you are about feeding your body, then you've got to check out my good friend and previous podcast guest's skincare line, Alitura Naturals. Alitura was created out of desperation after it's founder, model, and actor, Andy Hnilo, found his face unrecognizable after getting hit and run over by two cars. Alitura, latin for ‘feeding and nourishing,' was created out if a small studio apartment, purely out of necessity to heal Andy's scarring and abrasions. Carefully sourced with research proven ingredients containing natural, organic, nutrient-rich ingredients that feed and nourish your skin, so you can look as vibrant as you feel. And as a special gift for my listeners, use code “LIFESTYLIST” for 20% off and FREE SHIPPING in the US on your order at alituranaturals.com. AND… NOOTOPIA. Get four of the best brain-boosting mushroom extracts, plus collagen protein and Peruvian cacao, in Nootopia's new Collagenius. Go to nootopia.com/lukegenius and use code 'LUKE10' for 10% off. Resources: • Shop: Get 10% off at drinkupdate.com/luke • Instagram: @drinkupdate • Instagram: @shawnwells • Instagram: @danielsolomons_ • Are you ready to block harmful blue light, and look great at the same time? Check out Gilded By Luke Storey. Where fashion meets function: gildedbylukestorey.com • Join me on Telegram for the uncensored content big tech won't allow me to post. It's free speech and free content: www.lukestorey.com/telegram Related: • Trippy Tales: Amanita Muscaria Mushroom Micro + Macrodosing w/ Wild Forager, Laughing Dragon #483 • DMSO: The Most Suppressed Natural Remedy & Best-Kept Secret in the World? w/ Amandha Vollmer #480 • Integration Is Not Optional: Future of Psychedelic Coaching & Humanity's Healing w/ Tah + Kole #442 • Radical Redemption & Total Transformation w/ Tah & Kole Whitty #331 • Dissolving The Ego, Ketamine Therapy, & The Core Of Consciousness w/ Dr. Ted Achacoso #291 • Luke Solo Q&A Show: My Favorite Spiritual Tools & Supplements, EMDR, Hypnosis #241 • Mindset & Emotional Freedom: The Inner Work Of Biohacking w/ Dave Asprey #237 The Life Stylist is produced by Crate Media.
In today's trippy installment, I had the pleasure of sitting down with the man who calls himself the Laughing Dragon. He has turned the exploration of consciousness into a life path with the goal of uniting people through unconditional love. His disciplined lifestyle has the goal of holding the highest state of unconditional love possible. Prepare to be taken on a journey as Laughing Dragon shares his lessons from exploring the multiverse, sitting in ceremony with ayahuasca, and the transformative experiences available to expand our consciousness when partnering with plant medicine and psychedelics. The episode begins with Laughing Dragon opening up about his personal struggles early in life, including a challenging upbringing and overcoming insomnia and PTSD with the help of plant medicine and psychedelics. We dive deep into Laughing Dragon's captivating story, exploring how he stumbled upon the world of amanita muscaria mushrooms and what led him to embrace a path of shamanism. From there, we unravel the mysterious goals of the amanita muscaria experience and uncover the active ingredients responsible for its unique effects. Oh, and get ready for some mind-boggling folklore origins that connect Santa Claus himself to these magical mushrooms. Laughing Dragon also warns of the risks involved in microdosing amanita and imparts valuable lessons he's learned about consciousness from his daily ayahuasca use. If you're curious about foraging amanita muscaria in the United States or seeking microdosing recommendations, we've got you covered. And stay tuned to discover the intriguing story behind how Laughing Dragon earned his name. If you're curious about who psychedelics could help, how to use it, and ways to open a portal to other timelines, you're really going to dig this conversation. It's a wild ride, my friends. Let's dive in! DISCLAIMER: This podcast is presented for educational and exploratory purposes only. Published content is not intended to be used for diagnosing or treating any illness. Those responsible for this show disclaim responsibility for any possible adverse effects from the use of information presented by Luke or his guests. Please consult with your healthcare provider before using any products referenced. This podcast may contain paid endorsements for products or services. 00:00:07 — Laughing Dragon's Journey: Using Plant Medicine to Heal Trauma & Chronic Insomnia • Healing from a challenging upbringing and PTSD • How he got into the world of plant medicine and psychedelics • What led him to commit to a path of shamanism • When and how he turned a page on his health journey • Overcoming chronic insomnia • Discovering and dosing amanita muscaria • Goals of the amanita muscaria experience • Active ingredients that provide the experience • Animals and amanita mushrooms • How to identify amanita mushrooms • Looking out for dangerous mushrooms 00:24:32 — Amanita Muscaria: Legalities, Historical Relevance & Lessons in Consciousness • The legal situation of amanita muscaria • The Russian link to shamanism and embracing microcultures • Folklore origins that relate Santa Clause to amanita muscaria • Risks involved in microdosing amanita • Lessons learned about consciousness from daily ayahuasca use • Exploring different timelines in the multiverse • The key to changing humanity's consciousness 00:58:37 — The Spirituality of Death, Microdosing & The Birth of Laughing Dragon • Accepting death as a way to consciousness • Advice to anyone feeling hopeless in life • The spiritual implications of death by suicide • The process of foraging amanita muscaria in the U.S. • Microdosing and preparation recommendations • How gaba can physiologically impact REM sleep • The difference in consuming it in tinctures vs. tea • The story behind how he got his name More about this episode. Watch on YouTube. THIS SHOW IS BROUGHT TO YOU BY: JUST THRIVE. Nearly every American adult has insufficient levels of vitamin K2. Adding a daily dose of K2 to your supplement routine can lead to decreases in all cause mortality and cardiovascular risks. Get 15% off of Just Thrive's K2 with code LUKE15 at justthrivehealth.com. AND… BIOPTIMIZERS - the makers of Masszymes - are offering a challenge. This month only, get a FREE bottle of this best selling 100% plant-based, naturally-derived digestive enzymes - try and see all of the positive changes of enhanced digestion and nutrient absorption. All you have to do is pay a nominal shipping fee. That's it! Do not miss the opportunity, it is a limited time offer this month only. To get your free bottle, use code luke10 at masszymes.com/lukefree. AND… QUANTUM UPGRADE. Block harmful EMF with Quantum Upgrade's products. Their products stabilize the energy fields around you and work in the home, at the office, and even in your car. Get a 15 day free trial with code 'LUKE15' at quantumupgrade.io. AND… BON CHARGE. Enjoy the amazing benefits of infrared sauna in the comfort of your home at an affordable price. Burn calories, recover faster from aches and pains and calm your mind, body, and soul. Use the code LIFESTYLIST for 15% off at boncharge.com/lifestylist. Resources: • Catch Laughing Dragon at Psychedelic Awakening | Los Angeles, CA | July 27–29, 2023 • Website: amanitawarriors.com • Instagram: @amanitawarriors • You Tube: Amanita Warriors • Are you ready to block harmful blue light, and look great at the same time? Check out Gilded By Luke Storey. Where fashion meets function: gildedbylukestorey.com • Join me on Telegram for the uncensored content big tech won't allow me to post. It's free speech and free content: www.lukestorey.com/telegram Related: • Solving the Microdosing Mystery & the 3rd Wave of Psychedelics w/ Paul Austin #400 • Ketamine Therapy & the Psychedelic Medicine Revolution w/ Zappy Zapolin #393 • ‘Shroom Shaman Miracles & Mindful Meandering w/ Harry Paul #324 • Dissolving The Ego, Ketamine Therapy, & The Core Of Consciousness W/ Dr. Ted Achacoso #291 • Jungle Journeys: My Ayahuasca Awakening At Soltara (Part One) #262 • The Future Of Fungi: How Mushrooms Can Save Your Life (And The Planet) W/ Julian Mitchell #255 • The cosmic MD on LSD, Ayahuasca, & Nootropic Awakenings w/ Dr Ted Achacoso #227 • Welcome To The Jungle: My Ayahuasca Journey At Rythmia Part One #202 The Life Stylist is produced by Crate Media.
This is a special one, guys. It features my epic friends Tah and Kole. If you don't know their work yet, they host the Psychedelic Coach podcast and are co-creators of The Condor Approach, which is a psychedelic-informed certification for therapists, physicians, life coaches, and health experts. In addition to their next-level program, we unpack the many complexities behind this rapidly expanding field – from parsing language and potential legality outcomes to questions you should ask a facilitator candidate before embarking on your own journey. They are committed to building business structures that are contribution-driven and committed to reciprocity for indigenous communities. This dynamic duo is up to some great work guys, and we're gonna dig into it right here. Stick around for the outro as they surprise me with a live musical performance to close us out. Some of you will, no doubt, want to explore Tah and Kole's psychedelic-informed coaching program. You can do that by visiting lukestorey.com/tahkole. Use the code LUKE250 for $250 off the course! 00:05:07 — Catching Up With Tah & Kole Opening the conversation around psychedelics Radical shifts in what's possible Mas Vidal: Ayurveda and Yoga as a Way of Life #20 00:09:46 — Psychedelics in 2022 Harmful recreational drugs vs. plant medicine Emerging dysfunction in journey spaces Intention is everything Drug Use for Grown-Ups by Carl Hart Three levels of addiction Disintegration vs. integration 00:32:36 — Coaching, Facilitation & Ceremony Journey into stewardship Zero-harm integration model Laughing her way out of a ceremony Creating a place where people can be big VIDEO: Psychedelic Accessibility: Disability, Chronic Illness, & the Psychedelic Experience Luke and Alyson's experience with Wachuma The art of holding space Luke's first acid trip(s) 00:59:07 — The Condor Approach Trip sitter vs. space holder vs. facilitator vs. sherpa Psychedelic-informed coaching Ayauhasca's directions to Luke Intention ≠ outcome Get the course at lukestorey.com/tahkole – use LUKE250 for $250 off Optimizing our body's cues 5-day event in February (Austin) Kava Culture: Your Nervous System Solution w/ Cameron George #219 Modern issues in legislation, access, and proliferation Curiosity + courage = expansion Questions to ask your facilitator Modernizing while honoring tradition Integration is not optional Get the course at lukestorey.com/tahkole – use LUKE250 for $250 off 02:07:48 — Outro Musical Performance Mutual love for the shruti box Voice work of Maryn Azoff Voice work of @olox.life Transformational live music performance by Tah and Kole More about this episode. Watch on YouTube. THIS SHOW IS BROUGHT TO YOU BY: MAGNESIUM BREAKTHROUGH. According to the American Psychological Association, chronic stress is linked to the six leading causes of death. When most people think of stress, they think of their job, traffic, tense relationships, current events, things like that. But the root of so much of the stress we experience comes down to a deficiency in one overlooked nutrient — magnesium. So, if you're ready to help your body deal with stress, instead of putting a band-aid on it after the fact, you're going to want some Magnesium Breakthrough. During Bioptimizers' Black Friday special, you can use the code “luke10” for 25% OFF at magbreakthrough.com/luke. AND... TIMELINE NUTRITION. Mitopure is a breakthrough postbiotic that activates your body's natural defense against aging. Clinically proven to unlock the potent bioactive, Urolithin A. It is the purest form of Urolithin A, a molecule, which is only produced as a by-product when gut bacteria digest specific ingredients found in pomegranates. Go to “LUKE10” for 10% of any 2, 4 or 12-month Mitopure plans at timelinenutrition.com. AND… ORGANIFI RED. Recharge your mind and body with a delicious superfood berry blend of premium, organic superfoods that contain potent adaptogens, antioxidants and a clinical dose of cordyceps. Promote energy with zero caffeine and only 2 grams of sugar. Go to organifi.com/lifestylist and use code lifestylist for 20% off any item in the store. Resources: Instagram: @tahkole Podcast: The Psychedelic Coach Podcast Website: lukestorey.com/tahkole – Use code LUKE250 for $250 off the course! Are you ready to block harmful blue light, and look great at the same time? Check out Gilded By Luke Storey. Where fashion meets function: gildedbylukestorey.com Join me on Telegram for the uncensored content big tech won't allow me to post. It's free speech and free content: www.lukestorey.com/telegram Related: Ketamine Therapy & the Psychedelic Medicine Revolution w/ Zappy Zapolin #393 Radical Redemption & Total Transformation w/ Tah & Kole Whitty #331 Dissolving The Ego, Ketamine Therapy, & The Core Of Consciousness w/ Dr. Ted Achacoso #291
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