Podcasts about j am acad dermatol

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Best podcasts about j am acad dermatol

Latest podcast episodes about j am acad dermatol

Frankly Speaking About Family Medicine
A Clear Path to Acne Management: Key Takeaways from the Latest Guidelines - Frankly Speaking Ep 430

Frankly Speaking About Family Medicine

Play Episode Listen Later Apr 28, 2025 10:50


Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-430 Overview: Stay up to date with the latest evidence-based acne treatment guidelines from the American Academy of Dermatology (AAD). Learn how to optimize topical and oral therapies, minimize antibiotic resistance, and apply new best practices to improve outcomes for adolescents and young adults. Don't miss these key updates for enhancing patient care. Episode resource links: J Am Acad Dermatol 2024;90:1006.e1-30. doi.org/10.1016/j.jaad.2023.12.017 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Pri-Med Podcasts
A Clear Path to Acne Management: Key Takeaways from the Latest Guidelines - Frankly Speaking Ep 430

Pri-Med Podcasts

Play Episode Listen Later Apr 28, 2025 10:50


Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-430 Overview: Stay up to date with the latest evidence-based acne treatment guidelines from the American Academy of Dermatology (AAD). Learn how to optimize topical and oral therapies, minimize antibiotic resistance, and apply new best practices to improve outcomes for adolescents and young adults. Don't miss these key updates for enhancing patient care. Episode resource links: J Am Acad Dermatol 2024;90:1006.e1-30. doi.org/10.1016/j.jaad.2023.12.017 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

DermSurgery Digest
DermSurgery Digest At The Microscope: Perineural Invasion in Squamous Cell Carcinoma

DermSurgery Digest

Play Episode Listen Later Apr 16, 2025 22:04


This DermSurgery Digest bonus content aptly named “At the Microscope” shares the latest research and techniques in dermatopathology. In this episode, contributors will review the topic of perineural invasion in squamous cell carcinoma. Contributors to this podcast include Naomi Lawrence, MD, Dermatologic Surgery Digital Content Editor; Ashley Elsensohn, MD, MPH, DermSurgery Digest at the Microscope co-host; Christine Ahn, MD; Jeff Gardner, MD; Marina K. Ibraheim, MD; and Michael P. Lee, MD.Articles featured in this episode include:  Carter JB, Johnson MM, Chua TL, Karia PS, Schmults CD. Outcomes of primary cutaneous squamous cell carcinoma with perineural invasion: an 11-year cohort study. JAMA Dermatol. 2013 Jan;149(1):35-41. doi: 10.1001/jamadermatol.2013.746. PMID: 23324754 Link: https://pubmed.ncbi.nlm.nih.gov/23324754/Conde-Ferreirós A, Corchete LA, Jaka A, Santos-Briz Á, Fuente MJ, Posada R, Pons L, Podlipnik S, Pujol RM, Román-Curto C, Toll A, Cañueto J. Patterns of incidental perineural invasion and prognosis in cutaneous squamous cell carcinoma: A multicenter, retrospective cohort study. J Am Acad Dermatol. 2021 Jun;84(6):1708- 1712. doi: 10.1016/j.jaad.2020.08.017. Epub 2020 Aug 8. PMID: 32781186. Link: https://pubmed.ncbi.nlm.nih.gov/32781186/ Harvey NT, Palmer DJ, Tucker P, Chakera A, Foster R, Lim W, Trevithick RW, Wood BA. Histological predictors of outcome for cutaneous squamous cell carcinoma in renal transplant patients: A case-control study. JAAD Int. 2023 Dec 29;15:51-58. doi: 10.1016/j.jdin.2023.11.010. PMID: 38371661; PMCID: PMC10869928. Link: https://pubmed.ncbi.nlm.nih.gov/38371661/ Massey PR, Wang DM, Murad F, Mulvaney P, Moore K, Okhovat JP, Russell- Goldman E, Lin WM, Piris A, Huilgol SC, Ruiz ES, Schmults CD. Extensive Perineural Invasion vs Nerve Caliber to Assess Cutaneous Squamous Cell Carcinoma Prognosis. JAMA Dermatol. 2023 Dec 1;159(12):1332-1338. doi: 10.1001/jamadermatol.2023.3703. PMID: 37851425; PMCID: PMC10585586. Link: https://pubmed.ncbi.nlm.nih.gov/37851425/ Your feedback is encouraged. Please contact communicationstaff@asds.net.

DermSurgery Digest
DermSurgery Digest At The Microscope: Tumor Upstaging

DermSurgery Digest

Play Episode Listen Later Feb 18, 2025 19:16


This DermSurgery Digest bonus content, aptly named “At the Microscope,” shares the latest research and techniques in dermatopathology. In this episode, we will review tumor upstaging related to basal cell carcinoma, squamous cell carcinoma and melanoma. Contributors to this podcast include Naomi Lawrence, MD, Dermatologic Surgery Digital Content Editor; Ashley Elsensohn, MD, MPH, DermSurgery Digest at the Microscope co-host; Christine Ahn, MD; Jeff Gardner, MD; Marina K. Ibraheim, MD; and Michael P. Lee, MD. Articles featured in this episode include: Pham D, Tabba D, Zhou C, Chow C, Elsensohn A. Histopathological discrepancy of biopsy specimens compared to subsequent Mohs surgery or wide local excision specimens. J Am Acad Dermatol. 2024 Sep;91(3):518-519. doi: 10.1016/j.jaad.2024.04.047. Epub 2024 Apr 27. PMID: 38685403. Link: https://pubmed.ncbi.nlm.nih.gov/38685403/Lim GF, Perez OA, Zitelli JA, Brodland DG. Correlation of basal cell carcinoma subtype with histologically confirmed subclinical extension during Mohs micrographic surgery: A prospective multicenter study. J Am Acad Dermatol. 2022 Jun;86(6):1309-1317. doi: 10.1016/j.jaad.2022.02.037. Epub 2022 Feb 26. PMID: 35231546. Link: https://pubmed.ncbi.nlm.nih.gov/35231546/Knackstedt TJ, Brennick JB, Perry AE, Li Z, Quatrano NA, Samie FH. Frequency of squamous cell carcinoma (SCC) invasion in transected SCC in situ referred for Mohs surgery: the Dartmouth-Hitchcock experience. Int J Dermatol. 2015 Jul;54(7):830-3. doi: 10.1111/ijd.12867. Epub 2015 Apr 27. PMID: 25920731. Link: https://pubmed.ncbi.nlm.nih.gov/25920731/Jackett LA, Gullifer JP, Scolyer RA. Evaluation of Multiple Tissue Levels Frequently Upstages Patients With Clinically Localized Thin Primary Cutaneous Melanoma. J Cutan Pathol. 2024 Oct 2. doi: 10.1111/cup.14726. Epub ahead of print. PMID: 39357975. Link: https://pubmed.ncbi.nlm.nih.gov/39357975/ Your feedback is encouraged. Please contact communicationstaff@asds.net.

Pharmascope
Épisode 143 – Des petites réponses à des grosses questions

Pharmascope

Play Episode Listen Later Sep 29, 2024 37:49


Un nouvel épisode du Pharmascope est disponible! Dans ce 143e épisode dédié aux questions de nos fidèles auditeurs, Nicolas, Isabelle et Olivier tentent tant bien que mal de pondre des réponses intelligentes. Au menu : nomenclature des médicaments, thiamine, isotrétinoïne, anxiété et superpatch!  Les objectifs pour cet épisode sont : Comprendre la nomenclature des médicaments Discuter des bénéfices de la thiamine à titre d'agent répulsif Identifier des avantages et désavantages de l'isotrétinoïne à faible dose  Identifier de ressources pertinentes pour les patients pour le contrôle de l'anxiété Discuter des bénéfices des « superpatch » Ressources pertinentes en lien avec l'épisode ThiamineShelomi M. Thiamine (vitamin B1) as an insect repellent: a scoping review. Bull Entomol Res. 2022 Aug;112(4):431-440. Committee to Advise on Tropical Medicine and Travel (CATMAT). Statement on Personal Protective Measures to Prevent Arthropod Bites. 2012. Faible dose d'isotrétinoïneGravel A, Carreau S. L'isotrétinoïne efficace et bien tolérée, est-ce possible? Médecin du Québec, août 2022, 55-57. (Réservé aux abonnés). Brar K, Korownyk C. Is less more with isotretinoin and acne? Tools for practice. 2016. Strauss JS, Rapini RP, Shalita AR, Konecky E, Pochi PE, Comite H, Exner JH. Isotretinoin therapy for acne: results of a multicenter dose-response study. J Am Acad Dermatol. 1984 Mar;10(3):490-6. Lee JW, Yoo KH, Park KY, Han TY, Li K, Seo SJ, Hong CK. Effectiveness of conventional, low-dose and intermittent oral isotretinoin in the treatment of acne: a randomized, controlled comparative study. Br J Dermatol. 2011 Jun;164(6):1369-75. Agarwal US, Besarwal RK, Bhola K. Oral isotretinoin in different dose regimens for acne vulgaris: a randomized comparative trial. Indian J Dermatol Venereol Leprol. 2011 Nov-Dec;77(6):688-94. Dhaked DR, Meena RS, Maheshwari A, Agarwal US, Purohit S. A randomized comparative trial of two low-dose oral isotretinoin regimens in moderate to severe acne vulgaris. Indian Dermatol Online J. 2016 Sep-Oct;7(5):378-385. Ressources pour les patients pour l'anxiétéAnxiété Canada Centre d'études sur le stress humain TCC Montréal Psychopap Relief La clé des champs Phobies-zéro « Superpatch »Le Pharmachien : Super patch

DermSurgery Digest
DermSurgery Digest At The Microscope: Cutaneous and Subcutaneous Leiomyosarcoma

DermSurgery Digest

Play Episode Listen Later Aug 22, 2024 24:43


DermSurgery Digest at the Microscope dives deep into the latest dermatology literature exploring the latest techniques and diagnosis approaches. Each quarterly episode features interesting and relevant articles from Dermatologic Surgery, American Journal of Dermatopathology, Journal of Cutaneous Pathology, American Journal of Surgical Pathology and more.  This episode features articles on cutaneous and subcutaneous leiomyosarcoma.Contributors to this podcast include Naomi Lawrence, MD, Dermatologic Surgery Digital Content Editor; Ashley Elsensohn, MD, MPH, DermSurgery Digest At the Microscope co-host; Christine Ahn, MD; Jeff Gardner, MD; Marina K. Ibraheim, MD; and Michael P. Lee, MD.Articles featured include:Kraft S, Fletcher CD. Atypical intradermal smooth muscle neoplasms: clinicopathologic analysis of 84 cases and a reappraisal of cutaneous "leiomyosarcoma". Am J Surg Pathol. 2011 Apr;35(4):599-607. doi: 10.1097/PAS.0b013e31820e6093. PMID: 21358302.Kazlouskaya V, Lai YC, Khachemoune A. Leiomyosarcoma of the skin: review of the literature with an emphasis on prognosis and management. Int J Dermatol. 2020 Feb;59(2):165-172. doi: 10.1111/ijd.14705. Epub 2019 Nov 14. PMID: 31729020.Winchester DS, Hocker TL, Brewer JD, Baum CL, Hochwalt PC, Arpey CJ, Otley CC, Roenigk RK. Leiomyosarcoma of the skin: clinical, histopathologic, and prognostic factors that influence outcomes. J Am Acad Dermatol. 2014 Nov;71(5):919-25. doi: 10.1016/j.jaad.2014.07.020. Epub 2014 Aug 29. PMID: 25174541.Bresler SC, Gosnell HL, Ko JS, Angeles CV, Ronen S, Billings SD, Patel RM. Subcutaneous Leiomyosarcoma: An Aggressive Malignancy Portending a Significant Risk of Metastasis and Death. Am J Surg Pathol. 2023 Dec 1;47(12):1417-1424. doi: 10.1097/PAS.0000000000002126. Epub 2023 Sep 19. PMID: 37727934.Listeners are encouraged to submit questions for podcast hosts to answer in a later episode. To submit your questions, email communicationstaff@asds.net.

Evidence Based Hair
Season 7, Episode 9: Exploring Topical JAK Inhibitors for Scarring Alopecia

Evidence Based Hair

Play Episode Listen Later Jun 24, 2024 16:03 Transcription Available


Welcome back to another episode of the Evidence-Based Hair Podcast.   This week, we continue our June theme of JAK inhibitors, focusing on the use of topical JAK inhibitors for treating frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP). In this episode, we delve into a significant study by Dr. Maryanne Senna and colleagues from Boston, exploring the effectiveness and side effects of topical 2% tofacitinib for LPP and FFA. The study, involving 41 patients, provides valuable statistics on improvement and stabilization rates, offering practical insights for clinical application. We discuss the potential of topical JAK inhibitors, given their less systemic absorption compared to oral forms, and their specific relevance to scarring alopecia where inflammation is closer to the skin's surface. Despite some challenges with compounded topical formulations, the study's promising results highlight a third of patients showing improvement and over 60% achieving disease stabilization. Join us as we wrap up our June series on JAK inhibitors and prepare for July, where we'll focus on the antiandrogen spironolactone and its use in androgenetic hair loss in women.   Thank you for tuning in, and I look forward to our next discussion on the Evidence-Based Hair Podcast.   STUDY REFERENCED Li-Chi Chen, Chino Ogbutor, Kristen J Kelley, Maryanne M Senna. Topical tofacitinib for patients with lichen planopilaris and/or frontal fibrosing alopecia. J Am Acad Dermatol. 2024 Jun;90(6):1260-1262. doi: 10.1016/j.jaad.2024.01.060. Epub 2024 Feb 2.

Evidence Based Hair
Topical JAK Inhibitors: How well do they work for FFA/LPP?

Evidence Based Hair

Play Episode Listen Later Jun 24, 2024 16:03 Transcription Available


Welcome back to the Evidence-Based Hair Podcast! This episode continues our June theme on JAK inhibitors, focusing on their topical use for treating frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP). We'll delve into a groundbreaking study by Dr. Maryanne Senna and colleagues from Boston, examining the effectiveness and side effects of topical 2% tofacitinib for FFA and LPP. The study's results provide encouraging data, showing that about 31.6% of patients experienced improvement, and 60.5% saw disease stabilization. Join us as we explore the potential of topical JAK inhibitors in managing scarring alopecia, their practical applications, and the implications for future treatment protocols. Don't miss our insightful discussion on this emerging therapy and how it could transform patient care. Next month, we'll shift gears to discuss spironolactone and its role in treating androgenetic hair loss in women. Stay tuned!   STUDIES REFERENCED IN THIS EPISODE Li-Chi Chen, Chino Ogbutor, Kristen J Kelley, Maryanne M Senna. Topical tofacitinib for patients with lichen planopilaris and/or frontal fibrosing alopecia. J Am Acad Dermatol. 2024 Jun;90(6):1260-1262. doi: 10.1016/j.jaad.2024.01.060. Epub 2024 Feb 2.   Yang C.C., Khanna T., Sallee B., Christiano A.M., Bordone L.A.: Tofacitinib for the treatment of lichen planopilaris: a case series. Dermatol Ther 2018; 31:   Moussa A., Bhoyrul B., Asfour L., Kazmi A., Eisman S., Sinclair R.D.: Treatment of lichen planopilaris with baricitinib: a retrospective study. J Am Acad Dermatol 2022; 87: pp. 663-666.   Plante J., Eason C., Snyder A., Elston D.: Tofacitinib in the treatment of lichen planopilaris: a retrospective review. J Am Acad Dermatol 2020; 83: pp. 1487-1489.

Evidence Based Hair
"Unraveling the Link Between Dupilumab and Cutaneous T-Cell Lymphoma"

Evidence Based Hair

Play Episode Listen Later Apr 22, 2024 20:13 Transcription Available


Welcome to a new episode of the Evidence-Based Hair Podcast, where we discuss some questions surrounding the relationship between dupilumab and lymphoma. This episode dives deep into a study by Hasan and colleagues that explores the fascinating and somewhat controversial relationship between Dupilumab, a drug often used to treat atopic dermatitis patients with alopecia areata, and an increased risk of Cutaneous T-Cell Lymphoma (CTCL). Despite its potential benefits, does Dupilumab truly cause CTCL, or does it simply unmask the disease in patients who were previously misdiagnosed? Using information from a vast database, authors examined whether patients using dupilumab showed an increased incidence of CTCL compared to those who did not. Findings suggest that users of the drug have a four-fold increased risk of CTCL.   While uncertainties remain on whether Dupilumab triggers lymphomas, causes benign lymphoid reactions, or accelerates existing CTCL, this episode underscores the drug's potential risks and the importance of careful diagnostics before prescribing it. As we continue to gather data and debate the varying viewpoints, we invite you to join us in disentangling the complex relationship between Dupilumab and CTCL.  Stay tuned for our next episode, where we explore drug-induced alopecia areata and the potential triggering effects of new monoclonal antibodies.     donovanmedical  Edited• Season 7 of the Evidence Based Hair Podcast has started. This week I review several fascinating studies: The podcast can be accessed wherever you listen to your podcasts or via the DonovanMedical youtube channel. REFERENCES IN THIS EPISODE   Hasan I et al. Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: a retrospective cohort study. J Am Acad Dermatol. 2024 Apr 6:S0190-9622(24)00566-8. doi: 10.1016/j.jaad.2024.03.039. Online ahead of print. Jfri A et al. Diagnosis of mycosis fungoides or Sézary syndrome after dupilumab use: A systematic review. J Am Acad Dermatol . 2023 May;88(5):1164-1166. doi: 10.1016/j.jaad.2022.12.001. Epub 2022 Dec 5. Espinosa ML et al. Progression of cutaneous T-cell lymphoma after dupilumab: Case review of 7 patients. J Am Acad Dermatol . 2020 Jul;83(1):197-199. doi: 10.1016/j.jaad.2020.03.050. Epub 2020 Mar 27.

Evidence Based Hair
Top 20 Hair Research Studies of 2023

Evidence Based Hair

Play Episode Listen Later Dec 22, 2023 166:03


This is a recording from the live webinar was conducted live December 13, 2023. This is an annual event that is held every year in mid-December celebrating the top hair research studies.    DERMATOPATHOLOGY   Douglas A et al. Scalp Biopsy Influences Diagnostic Accuracy and Treatment in Black Women with Alopecia: A Retrospective Study. J Am Acad Dermatol. 2023 Jan 31;S0190-9622(23)00157-3.   ANDROGENETIC ALOPECIA Gupta AK et al.The relative efficacy of monotherapy with 5-alpha reductase inhibitors and minoxidil for female pattern hair loss: A network meta-analysis study. J Cosmet Dermatol. 2023 Jun 29 Jimenez-Cauhe J et al. Safety of Low-Dose Oral Minoxidil in Patients With Hypertension and Arrhythmia: A Multicenter Study of 264 Patients. Actas Dermosifiliogr. 2023 Aug 29:S0001-7310(23)00679-8.   ALOPECIA AREATA   Gandhi et al.The Association of Alopecia Areata-Related Emotional Symptoms with Work Productivity and Daily Activity Among Patients with Alopecia Areata. Dermatol Ther (Heidelb). 2023 Jan;13(1):285-298.   Li SJ et al. Experiencing Workplace Bullying in Patients with Alopecia Areata: A Cross-Sectional Survey Study. Skin Appendage Disord. 2023 Aug;9(4):258-261   Kazmi A et al. Switching between tofacitinib and baricitinib in alopecia areata: A review of clinical response. J Am Acad Dermatol. 2023 Apr 4;S0190-9622(23)00532-7.   King B et al. Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b-3 trial. Lancet. 2023 May 6;401(10387):1518-1529.   George P et al. Incidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database., Dermatol Ther (Heidelb). 2023 Aug; 13(8): 1733–1746.   Wang C-W et al. Clinical characteristics and immune profiles of patients with immune-mediated alopecia associated with COVID-19 vaccinations. Clin Immunol. 2023 Oct:255:109737.   Chen J et al. The Incidence of Alopecia Areata in a COVID-19- Vaccinated Population: A Single-Center Review. Cureus 2023   TELOGEN EFFLUVIUM   Michelini S et al. Telogen Effluvium in SARS-CoV-2 Infection: histological aspects. J Eur Acad Dermatol Venereol. 2023 Mar 8.   TINEA CAPITIS Gold, JA et al. Inadequate diagnostic testing and systemic antifungal prescribing for tinea capitis in an observational cohort study of 3.9 million children, United States. J Am Acad Dermatol. 2023 Feb 15;S0190-9622(23)00189-5.   COSMETIC DERMATOLOGY Landau M et al. Nonscarring alopecia after temporal lifting technique with dermal fillers. JAAD Case Rep. 2023 May 12;37   FOLLICULITIS DECALVANS Matard B et al. Folliculitis decalvans and dystrophic epidermolysis bullosa: a significant association. Br J Dermatol 2022 Dec;187(6):1026-1028. DISCOID LUPUS Fredeau L et al. Risk factors of progression from discoid lupus to severe systemic lupus erythematosus: a registry-based cohort study of 164 patients. J Am Acad Dermatol. 2023 Mar;88(3):551-559.   DISSECTING CELLULITIS Cajas-Garcia MS et al.  Distinct presentations of scalp dissecting cellulitis manifesting with furrows and gyri. J Eur Acad Dermatol Venereol. 2023 Feb 3.   LICHEN PLANOPILARIS Lim SH et al. Prevalence and Incidence of Comorbid Diseases and Mortality Risk Associated with Lichen Planopilaris: A Korean Nationwide Population-Based Study. Clin Exp Dermatol. 2023 Jul 11;llad235 GENERAL SCARRING ALOPECIA Kim SR et al.  Association of Primary Cicatricial Alopecia with Subsequent Cardiovascular Disease. J Invest Dermatol. 2023 Nov 19:S   CENTRAL CENTRIFUGAL CICATRICIAL ALOPECIA Joshi TP et al.  Comorbidities in patients with central centrifugal cicatricial alopecia: a case-control study. Int J Dermatol. 2023 Nov 23.   ACNE KELOIDALIS NUCHAE Lobato-Berezo A et al. Acne keloidalis nuchae: An international multicentric review of 79 patients. J Eur Acad Dermatol Venereol. 2023 Nov 1.

Evidence Based Hair
Season 6, Episode3 (Effect of Oral Minoxidil on Blood Pressure, Oral Minoxidil Use in Patients with High Blood Pressure and Arrhythmia)

Evidence Based Hair

Play Episode Listen Later Nov 6, 2023 38:06


ARTICLES COVERED THIS WEEK     STUDY 1: Ong M et al (starts at 5:12). Low-dose oral minoxidil for androgenetic alopecia is not associated with clinically significant blood-pressure changes: a retrospective study. J Am Acad Dermatol. 2023 Oct 13:S0190-9622(23)02976-6.    Sanabria et al. Prospective cardiovascular evaluation with 24-h Holter and 24-h ambulatory blood pressure monitoring in men using 5 mg oral minoxidil for androgenetic alopecia. J Am Acad Dermatol. 2022 May 18;   Jimenez-Cauhe J et al. Before-after study with 24-hour ambulatory blood pressure monitoring after the first dose of 5 mg oral minoxidil. J Am Acad Dermatol. 2022 Dec;87(6):e235-e237   STUDY 2:  Imhof R et al (starts at 16:35). Safety and tolerability of low dose oral minoxidil monotherapy in female pattern hair loss: A retrospective review with longitudinal ambulatory blood pressure monitoring. JAAD Int. 2023 Aug 12:13:50-52.   Ramos PM et al.  Minoxidil 1 mg versus minoxidil 5 % topical solution for the treatment of female-pattern hair loss: A randomized clinical trial. J Am Acad Dermatol Jan 2020;82(1):252-253.   STUDY 3:  Jimenez-Cauhe J  et al (starts at 24:27). Safety of Low-Dose Oral Minoxidil in Patients With Hypertension and Arrhythmia: A Multicenter Study of 264 Patients. Actas Dermosifiliogr. 2023 Aug 29:S0001-7310(23)00679-8.   Vano-Galvan S et al. Safety of  low dose oral  minoxidil for hair loss: A multicenter study of 1404 patients. JAAD 2021; 84: 1644-51.   Sanabria B et al. Adverse effects of low dose oral minoxidil for androgenetic alopecia in 435 patients. JAAD 2021; 84: 1175-78.     ARITCLES COVERED NEXT WEEK (PREVIEW)   Cook M et al. Use of low-level light therapy in management of central centrifugal cicatricial alopecia: A case series of four patients. Photodermatol Photoimmunol Photomed. 2023 Aug 23.   Workman K and Kindred C. Hair regrowth in a patient with central centrifugal cicatricial alopecia after a 2-month trial of baricitinib. JAAD Case Rep. 2023 Jul 28:39:109-111

Evidence Based Hair
Season 6, Episode 2 (A Closer Look at Randomized Controlled Trials and Real World Non RCT Data)

Evidence Based Hair

Play Episode Listen Later Nov 4, 2023 26:32


ARTICLES REFERENCED IN THIS EPISODE   Krauss A (starts at 12:44). Why all randomised controlled trials produce biased results. Ann Med. 2018 Jun;50(4):312-322.   Van Noreen R (starts at 15:33). Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed? Nature. 2023 Jul;619(7970):454-458. Listen at https://youtu.be/_QLvzCr6nz4?feature=shared   Carlisle JB (starts at 16:28). False individual patient data and zombie randomised controlled trials submitted to Anaesthesia. Anaesthesia. 2021 Apr;76(4):472-479.       PREVIEW STUDIES FOR NEXT WEEK  (SEASON 6, EPISODE 3) Ong M et al. Low-dose oral minoxidil for androgenetic alopecia is not associated with clinically significant blood-pressure changes: a retrospective study. J Am Acad Dermatol. 2023 Oct 13:S0190-9622(23)02976-6. doi: 10.1016/j.jaad.2023.10.010. Online ahead of print. Jimenez-Cauhe et al. Safety of Low-Dose Oral Minoxidil in Patients With Hypertension and Arrhythmia: A Multicenter Study of 264 Patients. Actas Dermosifiliogr. 2023 Aug 29:S0001-7310(23)00679-8. Imhof R et al. Safety and tolerability of low dose oral minoxidil monotherapy in female pattern hair loss: A retrospective review with longitudinal ambulatory blood pressure monitoring. JAAD Int. 2023 Aug 12:13:50-52.

Evidence Based Hair
Season 5, Episode 5 (CCCA Prognosis, CCCA in Males, Anagen Hairs in LPP, EPDS and NMSC and FD in Females)

Evidence Based Hair

Play Episode Listen Later Aug 21, 2023 62:43


STUDIES REFERENCED IN THIS EPISODE Onamusi T et al (starts at 8:58). Clinical factors and hair care practices influencing outcomes in central centrifugal cicatricial alopecia. Arch Dermatol Res. 2023 May 15. doi: 10.1007/s00403-023-02630-5. Online ahead of print.   Erinolaoluwa F et al (starts at 11:59). Hair regrowth in 2 patients with recalcitrant central centrifugal cicatricial alopecia after use of topical metformin. JAAD Case Reports Feb 2020   Jackson TK et al (starts at 15:40). Central Centrifugal Cicatricial Alopecia in Males. J Am Acad Dermatol. 2023 Jul 24:S0190-9622(23)02399-X.   Melo RR et al (starts at 21:45). Positive Anagen Pull Test Predicting Lichen Planopilaris Activity. Dermatol Pract Concept. 2023 Jul 1;13(3):e2023140.   Shamloul N et al (starts at 29:14). Incidence and time to development of malignancies arising on the scalp of patients with erosive pustular dermatosis based on sex: A retrospective analysis. J Am Acad Dermatol. 2023 Jun 13;S0190-9622(23)01111-8.   Negbenebor NA et al (starts at 34:45). Nonmelanoma skin cancer in the setting of erosive pustular dermatosis of the scalp: A case series and comment on management implications. Dermatol Ther. 2022 Jul;35(7):e15584. doi: 10.1111/dth.15584. Epub 2022 May 28.   Sarkis A et al (starts at 41:54). Folliculitis Decalvans in women: a retrospective multicenter study of 150 patients. J Eur Acad Dermatol Venereol. 2023 Aug 18.   Vañó-Galván S et al (starts at 43:39). Folliculitis decalvans: a multicentre review of 82 patients. J Eur Acad Dermatol Venereol. 2015 Sep;29(9):1750-7.

Evidence Based Hair
Season 5, Episode 4 (Switching JAK Inhibitors, Ritlecitinib in Adolescents, VTE Risk in AT/AU, Habit Replacement Therapy in TTM)

Evidence Based Hair

Play Episode Listen Later Aug 14, 2023 80:28


STUDIES REFERENCE IN THE EPISODE   SWITCHING FROM TOFACITINIB TO BARICITINIB   Kazmi A et al (starts at 12:33). Switching between tofacitinib and baricitinib in alopecia areata: A review of clinical response. J Am Acad Dermatol. 2023 Apr 4;S0190-9622(23)00532-7.     RITLECITINIB IN ADOLESCENTS   Hordinsky M et al (starts at 21:31). Efficacy and safety of ritlecitinib in adolescents with alopecia areata: Results from the ALLEGRO phase 2b/3 randomized, double-blind, placebo-controlled trial. Pediatr Dermatol. 2023 Jul 17.     RISK OF INFECTIONS, CANCER, HEART DISEASE AND BLOOD CLOTS IN AT/AU   George P et al (starts at 36:08). Incidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database., Dermatol Ther (Heidelb). 2023 Aug; 13(8): 1733–1746.     Schneeweiss MC et al (starts at 37:36). Incidence of Venous Thromboembolism in Patients With Dermatologist-Diagnosed Chronic Inflammatory Skin Diseases. JAMA Dermatol. 2021 Jul 1;157(7):805-816.     MARKERS OF VENOUS THROMBOEMBOLISM IN ALOPECIA AREATA   Sudnik W et al (starts at 57:40) . The role of selectins in alopecia areata. Postepy Dermatol Alergol. 2015 Feb;32(1):27-32.   Shakoei S et al (starts at 58:23). Coagulation status in patients with alopecia areata: a cross-sectional study. Ital J Dermatol Venerol. 2021 Oct;156(5):588-592.   Waśkiel-Burnat A et al (starts at 59:30). Markers of Venous Thromboembolism Risk in Patients with Alopecia Areata: Is There Anything to Worry about? Dermatol Ther (Heidelb). 2023 Aug;13(8):1847-1855.     HABIT REPLACEMENT THERAPY FOR TRICHOTILLOMANIA   Moritz S et al (starts at 1:04:34). Self-Help Habit Replacement in Individuals With Body-Focused Repetitive Behaviors: A Proof-of-Concept Randomized Clinical Trial.  JAMA Dermatol. 2023 Jul 19;e232167.   LINK TO VIDEO on HRT DEMONSTRATION https://clinical-neuropsychology.de/habit-replacement-en/#sthash.J6iQiYRi.dpuf    

Evidence Based Hair
Season 5 Episode 1 (LPP Disease Associations, LPP & Thyroid, Side Effects of HCQ, Genetic Basis of Male FFA, FFA Prevalence/Incidence)

Evidence Based Hair

Play Episode Listen Later Jul 17, 2023 65:31


DISEASE ASSOCIATIONS IN FRONTAL FIBROSING ALOPECIA Conic et al. Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders. J Eur Acad Dermatol Venereol 2021 Nov;35(11):e826-e828.    Joshi et al. Comorbidities associated with lichen planopilaris: a case-control study using the All of Us database. Int J Dermatol. 2022 Oct 2.   Lim SH Prevalence and Incidence of Comorbid Diseases and Mortality Risk Associated with Lichen Planopilaris: A Korean Nationwide Population-Based Study. Clin Exp Dermatol. 2023 Jul 11;llad235     THE RELATIONSHIP BETWEEN LPP AND HYPOTHYROIDISM   Joshi TP et al. Association of lichen planopilaris with hypothyroidism: a systematic review and meta-analysis. Int J Dermatol. 2023 Jul 10.     SIDE EFFECTS OF HYDROXYCHLOROQUINE IN PATIENTS WITH SCARRING ALOPECIA     Ezemma O et al. Adverse effects of hydroxychloroquine use in patients with cicatricial alopecia: A systematic review. Int J Dermatol. 2023 Apr 10. doi: 10.1111/ijd.16660. Online ahead of print     GENETICS OF MALE FRONTAL FIBROSING ALOPECIA   Rayinda T et al. Shared Genetic Risk Variants in Both Male and Female Frontal Fibrosing Alopecia. J Invest Dermatol. 2023 May 19;S0022-202X(23)02068-7.       INCIDENCE AND PREVALENCE OF FRONTAL FIBROSING ALOPECIA   Lavian J et al. Incidence estimates for lichen planopilaris and frontal fibrosing alopecia in a New York City health care system. Dermatol Online J. 2021 Aug 15;27(8).   Trager MH et al. Prevalence estimates for lichen planopilaris and frontal fibrosing alopecia in a New York City health care system. J Am Acad Dermatol 2021 Apr;84(4):1166-1169   Carmona-Rodriquez M et al. Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases. Life (Basel). 2023 Jun 8;13(6):1344.

Dr. Brendan McCarthy
Fixing Acne with Hormones - Ep. 23

Dr. Brendan McCarthy

Play Episode Listen Later Mar 20, 2023 27:41


Welcome to the podcast with Dr. Brendan McCarthy! Do you continue to see acne along your lower face, jawline, and neck despite trying all sorts of acne treatments? Have you taken an antibiotic to treat your acne and been disappointed with the results? Are you struggling to clear acne on your chest or back as well? Women who answer yes to any of these questions may want to consider hormonal therapy for acne. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he's been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- YouTube: www.youtube.com/drbrendanmccarthy Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com #hormonalacne #acnetreatment #acneproneskin #acneremoval #acne Recommended research Panzer, Claudia et al. “Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: a retrospective study in women with sexual dysfunction.” The journal of sexual medicine vol. 3,1 (2006): 104-13. doi:10.1111/j.1743-6109.2005.00198. Eichenfield LF, Krakowski AC, Piggott C, Del Rosso J, Baldwin H, Friedlander SF, Levy M, Lucky A, Mancini AJ, Orlow SJ, Yan AC, Vaux KK, Webster G, Zaenglein AL, Thiboutot DM; American Acne and Rosacea Society. Evidence-based recommendations for the diagnosis and treatment of pediatric acne. Pediatrics. 2013 May;131 Suppl 3:S163-86. doi: 10.1542/peds.2013-0490B. PMID: 23637225. Bachmann G., Bancroft J., Braunstein G., et al: Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment. Fertil Steril 2002; 77: pp. 660-665 Eichenfield DZ et al: Management of acne vulgaris: a review. JAMA. 326(20):2055-67, 2021 Zaenglein AL: Acne vulgaris. N Engl J Med. 379(14):1343-52, 2018 Penso L et al: Association between adult acne and dietary behaviors: findings from the NutriNet-Santé prospective cohort study. JAMA Dermatol. 156(8):854-62, 2020 Dall'Oglio F et al: Diet and acne: review of the evidence from 2009 to 2020. Int J Dermatol. 60(6):672-85, 2021 Zaenglein AL et al: Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 74(5):945-73, 2016 Bienenfeld A et al: Androgens in women: androgen-mediated skin disease and patient evaluation. J Am Acad Dermatol. 80(6):1497-506, 2019

Evidence Based Hair
Season 4, Episode 4 (COVID hair loss, TE from anti-CGRP migraine meds, tinea capitis, oral minoxidil for traction alopecia

Evidence Based Hair

Play Episode Listen Later Mar 13, 2023 75:20


Season 4 Episode 4   COVID RELATED TE Michelini S et al. Telogen Effluvium in SARS-CoV-2 Infection: histological aspects. J Eur Acad Dermatol Venereol.  2023 Mar 8. M Alharbi et al. Telogen effluvium after COVID-19 vaccination among public in Saudi Arabia. J Family Med Prim Care. 2022 Oct;11(10):6056-6060. Tahmaz A et al. [The Evaluation of Long Coronavirus Disease Symptoms at Ninth Month from a Hospital in Türkiye]. .Mikrobiyol Bul. 2022 Oct;56(4):657-666. Saber M et al. Scalp capillarectasia as a trichoscopic sign of COVID-19-associated telogen effluvium. J Cosmet Dermatol. 2023 Mar 9 Lv S et al. A Case of Acute Telogen Effluvium After SARS-CoV-2 Infection Clin Cosmet Investig Dermatol. 2021; 14: 385–387. Published online 2021 Apr 16.  Willimann B, et al. Hair pain (trichodynia): frequency and relationship to hair loss and patient gender. Dermatology. 2002   HAIR LOSS FROM ANTI-CGRP THERAPIES Ruiz M et al. Alopecia as an emerging adverse event to CGRP monoclonal antibodies: Cases Series, evaluation of FAERS, and literature review. Cephalalgia. 2023 Feb;43(2):3331024221143538.   Sessa M and Andersen M. New insight on the safety of erenumab: an analysis of spontaneous reports of adverse events recorded in the US Food and Drug Administration Adverse Event Reporting System Database. BioDrugs 2021; 35: 215–227   Evers S and Wald S. Effluvium and alopecia associated with monoclonal calcitonin gene-related peptide antibody use. Headache. 2023 Jan;63(1):165-167.   ORAL MINOXIDIL FOR TRACTION ALOPECIA Awad A et al. Low-dose oral minoxidil improves hair density in traction alopecia. J Am Acad Dermatol. 2023 Feb 24;S0190-9622(23)00278-5. Beach RA. Case series of oral minoxidil for androgenetic and traction alopecia: Tolerability & the five C's of oral therapy. Dermatol Ther. 2018 Nov;31(6):e12707. Kim and Craiglow. Treatment of traction alopecia with oral minoxidil. JAAD Case Rep. 2022 Apr 1;23:112-113.   TINEA CAPITIS WORK UP AND TREATMENT IN PEDIATRICS Gold, JA et al. Inadequate diagnostic testing and systemic antifungal prescribing for tinea capitis in an observational cohort study of 3.9 million children, United States. J Am Acad Dermatol. 2023 Feb 15;S0190-9622(23)00189-5.

Evidence Based Hair
Season 4, Episode 2 (Scalp Bx for Black Women, Oral Minoxidil for Chemotherapy Hair Loss, Folliculotropic MF, Atrichia with Papular Lesions, MTX and Liver Fibrosis)

Evidence Based Hair

Play Episode Listen Later Mar 1, 2023 73:05


STUDIES REFERENCED   ROLE OF SCALP BIOPSIES IN BLACK WOMEN WITH HAIR LOSS   Douglas A et al. Scalp Biopsy Influences Diagnostic Accuracy and Treatment in Black Women with Alopecia: A Retrospective Study. J Am Acad Dermatol. 2023 Jan 31;S0190-9622(23)00157-3.    ORAL MINOXIDIL IN CHEMOTHERAPY RELATED HAIR LOSS   Kang J et al. Efficacy of low-dose oral minoxidil in the management of anticancer therapy-induced alopecia in patients with breast cancer: A retrospective cohort study. J Am Acad Dermatol 2022 Dec 13;S0190-9622(22)03261-3.     FOLLICULOTROPIC MYCOSIS FUNGOIDES   Paolino G et al. Widespread and eruptive comedonal lesions with alopecia. JAAD Case Rep . 2022 Nov 1;31:23-26.  Kreutzer and Effendy. Cicatricial Alopecia Related to Folliculotropic Mycosis Fungoides. Dermatol Ther (Heidelb). 2020 Oct;10(5):1175-1180 Gallo G et al Clinical and trichoscopic features in 18 cases of Folliculotropic Mycosis Fungoides with scalp involvement. Scientific Reports.  2021 May 18;11(1):10555.     ATRICHIA WITH PAPULES LESIONS   Boisen J et al. Atrichia With Papular Lesions Confirmed via Genetic Testing: A Case Report. Cureus 2022 Dec; 14(12): e32562. Zlotogorski A, Panteleyev AA, Aita VM, Christiano AM. Clinical and molecular diagnostic criteria of congenital atrichia with papular lesions. J Invest Dermatol 2002; 118: 887–890 Yip L, Horev L, Sinclair R, et al. Atrichia with papular lesions: a report of three novel human hairless gene mutations and a revision of diagnostic criteria. Acta Derm Venereol 2008; 88(4): 346–349. Bergman R et al. The alopecias associated with vitamin D-dependent rickets type IIA and with hairless gene mutations: a comparative clinical, histologic, and immunohistochemical study. Arch Dermatol. 2005 Mar;141(3):343-51.     METHOTREXATE AND LIVER FIBROSIS Atallah  E et al. Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated. J Hepatol . 2023 Jan 23;S0168-8278(23)00020-X.   Conway R, Low C, Coughlan RJ, O'Donnell MJ, Carey JJ. Risk of liver injury among methotrexate users: a meta-analysis of randomised controlled trials. Semin Arthritis Rheum 2015;45(2):156–162   Cheema HI et al. Review of existing evidence demonstrates that methotrexate does not cause liver fibrosis. J Investig Med. 2022 Oct;70(7):1452-1460.

Evidence Based Hair
Season 4, Episode 1 (HCQ and Retinopathy Risk, FD Microbiome, LDN for LPP, TNF Inhibitors for DSC)

Evidence Based Hair

Play Episode Listen Later Feb 21, 2023 88:55


STUDIES REFERENCED   PATHOLOGY OF NON SCARRING AND SCARRING ALOPECIA   Amanda Araujo Dos Reis Botega et al. Scarring versus Non-Scarring Alopecia: An Interobserver Histopathological Reproducibility Study Skin Appendage Disord. 2023 Jan;9(1):34-41. doi: 10.1159/000526966. Epub 2022 Nov 25.     HYDROXYCHLOROQUINE AND RETINOPATHY RISK   Ronald B Melles RB et al. Hydroxychloroquine Dose and Risk for Incident Retinopathy : A Cohort Study. Ann Intern Med. 2023 Jan 17.   LOW DOSE NALTREXONE IN LICHEN PLANOPILARIS   Lajevardi et al. The efficacy and safety of oral low dose naltrexone versus placebo in the patients with lichen planopilaris: a randomized controlled trial. J Dermatol Treat. Jun 2020   Hamel RK et al. Oral Low-Dose Naltrexone in the Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: An Uncontrolled Open-Label Prospective Study. Cureus Jan 2023.   Toledo-Pastrana et al. Perifollicular Erythema as a Trichoscopy Sign of Progression in Frontal Fibrosing Alopecia. Int J Trichology. 2013 Jul-Sep; 5(3): 151–153.     ACTINIC LICHEN PLANOPILARIS Lalagianni N et al. Actinic lichen planopilaris: a new variant of lichen planopilaris triggered by ultraviolet radiation. Clin Exp Dermatol. 2023 Feb 2;48(2):158-160.     FOLLICULITIS DECALVANS MICROBIOME STUDIES   Moreno-Arrones OM et al. Folliculitis decalvans has a heterogeneous microbiological signature and impaired immunological response. Dermatology. 2023 Jan 30.   Moreno-Arrones et al. Folliculitis decalvans microbiologic signature is specific for disease clinical phenotype. J Am Acad Dermatol. 2021 Nov;85(5):1355-1357.     TNF INHIBITORS IN DISSECTING CELLULITIS Alzahrani M et al. Treatment of dissecting cellulitis of the scalp with tumor necrosis factor inhibitors: a retrospective multicenter STUDY. Clin Exp Dermatol. 2023 Jan 26;llad036.

Evidence Based Hair
Season Finale (PART 2 of 2): Top 20 Hair Research Studies of 2022

Evidence Based Hair

Play Episode Listen Later Dec 23, 2022 54:53


The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in hair shedding, scarring alopecia, seborrheic dermatitis and hair straighteners (studies 12 to 20). Studies 1 to 11 are found in Part 1 (season 3 episode 9)     STUDIES IN HAIR SHEDDING/TELOGEN EFFLUVIUM/ COVID19   STUDY 12: Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26.   STUDY 13: Anna Carolina Miola et al. Early-onset effluvium secondary to COVID-19: Clinical and histologic characterization. J Am Acad Dermatol. 2022   STUDY 14: Mazeto IFS et al. Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20.     STUDIES IN SCARRING ALOPECIA   STUDY 15: Dubin C et al. Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016   STUDY 16: Jamerson et al. Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes Exp Dermatol. 2022 Jan   STUDY 17: Joshi TP et al. Prevalence of lichen planopilaris in the United States: A cross-sectional study of the All of Us research program. JAAD Int. 2022 Jun 13;8:69-70.   STUDY 18: Joshi et al. Comorbidities associated with lichen planopilaris: a case-control study using the All of Us database. Int J Dermatol. 2022 Oct 2.     STUDIES  IN VARIOUS TOPICS   STUDY 19: Chang CJ et al. Use of Straighteners and Other Hair Products and Incident Uterine Cancer. J Natl Cancer Inst. 2022 Oct 17;djac165.   STUDY 20: Ying-Yi Lu et al. Impact of seborrheic dermatitis on osteoporosis risk: A population-based cohort study. J Dermatol. 2022 Sep 12.     STUDIES IN PART 1 of PODCAST  STUDIES IN AGA STUDY 1: Qui Y et al. Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol. 2022 Feb 8;102:adv00645 STUDY 2: Cao L et al. Nailfold capillaroscopy alterations in androgenetic alopecia: A cross-sectional study. Indian J Dermatol Venereol Leprol. 2022 Feb 28;1-7. doi: 10.25259/IJDVL_714_2021. STUDY 3: Sanabria et al. Prospective cardiovascular evaluation with 24-h Holter and 24-h ambulatory blood pressure monitoring in men using 5 mg oral minoxidil for androgenetic alopecia. J Am Acad Dermatol. 2022 May 18;   STUDY 4: Jimenez-Cauhe J et al. Before-after study with 24-hour ambulatory blood pressure monitoring after the first dose of 5 mg oral minoxidil. J Am Acad Dermatol. 2022 Dec;87(6):e235-e237.   STUDY 5: Gupta AK et al. Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. 2022 Feb 2:e215743.   STUDY 6: Gupta AK and Bamimore M. Platelet-Rich Plasma Monotherapies for Androgenetic Alopecia: A Network Meta-Analysis and Meta-Regression Study. J Drugs Dermatol. 2022 Sep 1;21(9):943-952.   STUDY 7: Gupta AK et al. There Is a Positive Dose-Dependent Association between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings from a Systematic Review with Meta-Regression Analyses. Skin Appendage Disord. 2022 Sep; 8(5): 355–36   STUDY 8: Klein E et al. Comparing combination low-dose oral minoxidil and topical minoxidil with oral minoxidil alone for the treatment of non-scarring alopecia; a retrospective chart review. J Cosmet Dermatol. 2022 Jun 1.   STUDY 9: Liang  X et al. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial. Front Med (Lausanne). 2022 Jul 11;9:905140.   STUDIES IN ALOPECIA AREATA     STUDY 10: King B et al. Two Phase 3 Trials of Baricitinib for                  Alopecia Areata. N Engl J Med. 2022 Mar 26.   STUDY 11: Anna Waśkiel-Burnat et al. Patients with alopecia areata are at risk of endothelial dysfunction: results of a case-control study. Clin Exp Dermatol. 2022 Mar 31.  

Evidence Based Hair
Season Finale (PART 1 of 2): Top 20 Hair Research Studies of 2022

Evidence Based Hair

Play Episode Listen Later Dec 23, 2022 77:33


The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in androgenetic alopecia and alopecia areata (studies 1 to 11). Studies 12 to 20 are found in Part 2 (season 3 episode 10)   STUDIES IN FEMALE PATTERN HAIR LOSS AND MALE PATTERN HAIR LOSS STUDY 1: Qui Y et al. Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol. 2022 Feb 8;102:adv00645 STUDY 2: Cao L et al. Nailfold capillaroscopy alterations in androgenetic alopecia: A cross-sectional study. Indian J Dermatol Venereol Leprol. 2022 Feb 28;1-7. doi: 10.25259/IJDVL_714_2021. STUDY 3: Sanabria et al. Prospective cardiovascular evaluation with 24-h Holter and 24-h ambulatory blood pressure monitoring in men using 5 mg oral minoxidil for androgenetic alopecia. J Am Acad Dermatol. 2022 May 18;   STUDY 4: Jimenez-Cauhe J et al. Before-after study with 24-hour ambulatory blood pressure monitoring after the first dose of 5 mg oral minoxidil. J Am Acad Dermatol. 2022 Dec;87(6):e235-e237.   STUDY 5: Gupta AK et al. Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. 2022 Feb 2:e215743.   STUDY 6: Gupta AK and Bamimore M. Platelet-Rich Plasma Monotherapies for Androgenetic Alopecia: A Network Meta-Analysis and Meta-Regression Study. J Drugs Dermatol. 2022 Sep 1;21(9):943-952.   STUDY 7: Gupta AK et al. There Is a Positive Dose-Dependent Association between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings from a Systematic Review with Meta-Regression Analyses. Skin Appendage Disord. 2022 Sep; 8(5): 355–36   STUDY 8: Klein E et al. Comparing combination low-dose oral minoxidil and topical minoxidil with oral minoxidil alone for the treatment of non-scarring alopecia; a retrospective chart review. J Cosmet Dermatol. 2022 Jun 1.   STUDY 9: Liang  X et al. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial. Front Med (Lausanne). 2022 Jul 11;9:905140.   STUDIES IN ALOPECIA AREATA     STUDY 10: King B et al. Two Phase 3 Trials of Baricitinib for                  Alopecia Areata. N Engl J Med. 2022 Mar 26.   STUDY 11: Anna Waśkiel-Burnat et al. Patients with alopecia areata are at risk of endothelial dysfunction: results of a case-control study. Clin Exp Dermatol. 2022 Mar 31.     STUDIES IN HAIR SHEDDING/TELOGEN EFFLUVIUM/ COVID19   STUDY 12: Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26.   STUDY 13: Anna Carolina Miola et al. Early-onset effluvium secondary to COVID-19: Clinical and histologic characterization. J Am Acad Dermatol. 2022   STUDY 14: Mazeto IFS et al. Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20.     STUDIES IN SCARRING ALOPECIA   STUDY 15: Dubin C et al. Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016   STUDY 16: Jamerson et al. Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes Exp Dermatol. 2022 Jan   STUDY 17: Joshi TP et al. Prevalence of lichen planopilaris in the United States: A cross-sectional study of the All of Us research program. JAAD Int. 2022 Jun 13;8:69-70.   STUDY 18: Joshi et al. Comorbidities associated with lichen planopilaris: a case-control study using the All of Us database. Int J Dermatol. 2022 Oct 2.     STUDIES  IN VARIOUS TOPICS   STUDY 19: Chang CJ et al. Use of Straighteners and Other Hair Products and Incident Uterine Cancer. J Natl Cancer Inst. 2022 Oct 17;djac165.   STUDY 20: Ying-Yi Lu et al. Impact of seborrheic dermatitis on osteoporosis risk: A population-based cohort study. J Dermatol. 2022 Sep 12.

Evidence Based Hair
Season 3, Episode 6 (Hydroxychloroquine and Oral Minoxidil for LPP, Gout in AKN, Shingles and EPDS, Renbok phenomenon, ACD in FFA/LPP)

Evidence Based Hair

Play Episode Listen Later Nov 21, 2022 65:03


LEARNING OBJECTIVES By the end of the podcast, the listener should be able to Discuss the benefits of HCQ in LPP Outline allergens that may be relevant in LPP/FFA Discuss the benefits of LDOM in LPP Describe the Renbok phenomenon and how it relates to FFA Outline the potential triggers for EPDS Describe the relationship between AKN and gout     EFFICACY OF HYDROXYCHLOROQUINE IN LICHEN PLANOPILARIS   Vastarella M et al (starts at 6:08). Efficacy and safety of hydroxychloroquine for the management of lichen planopilaris in a real-life setting. Ital J Dermatol Venerol. 2022 Jun;157(3):296-297.   Chiang C et al (starts at 14:17). Hydroxychloroquine and lichen planopilaris: efficacy and introduction of Lichen Planopilaris Activity Index scoring system. J Am Acad Dermatol. 2010 Mar;62(3):387-92.   Dhonncha EN et al (starts at 16:05). The role of hydroxychloroquine in the treatment of lichen planopilaris: A retrospective case series and review. Dermatol Ther. 2017 May;30(3).       ALLERGIC CONTACT DERMATITIS IN LICHEN PLANOPILARIS AND FRONTAL FIBROSING ALOPECIA   Prasad et al (starts at 18:38). Patch testing and contact allergen avoidance in patients with lichen planopilaris and/or frontal fibrosing alopecia: A cohort study J Am Acad Dermatol Aug 2020   Shtaynberger B et al (starts at 22:51). The Prevalence of Type IV Hypersensitivity in Patients With Lichen Planopilaris and Frontal Fibrosing Alopecia. Dermatitis. 2022 Oct 17.       USE OF ORAL MINOXIDIL IN LICHEN PLANOPILARIS   Vano-Galvan S et al (starts at 36:42). Oral minoxidil improves background hair thickness in lichen planopilaris. J Am Acad Dermatol 2021 Jun;84(6):1684-1686.     Giuseppe Gallo et al (starts at 37:45). Low-dose oral minoxidil in female patients with lichen planopilaris: Real-life experience. J Eur Acad Dermatol Venereol. 2022 Aug 16         RENBOK PHENOMENON IN FRONTAL FIBROSING ALOPECIA   Sławińska M et al (starts at 42:29). Frontal fibrosing alopecia sparing a dermal melanocytic nevus: a report of two cases of Renbök phenomenon. J Eur Acad Dermatol Venereol. 2022 Dec;36(12):e1042-e1043.   EROSIVE PUSTULAR DERMATOSIS AND SHINGLES   Salah NB et al (starts at 45:21). Erosive pustular dermatosis of the scalp in the COVID-19 era. J Cosmet Dermatol. 2022 Nov 14.   Akpandak I et al (starts at 50:55). Assessment of Herpes Zoster Risk Among Recipients of COVID-19 Vaccine. JAMA Netw Open 2022 Nov 1;5(11):e2242240.     RISK OF GOUT IN ACNE KELOIDALIS Eran Shavit et al (starts at 53:40). The burden of gout in acne keloidalis nuchae-Insights from a population-based study. J Cosmet Dermatol. 2022 Nov 8.

Evidence Based Hair
Season 3, Episode 4 (Oral Minoxidil for AGA, JAKI for AGA, PRP for AGA,COVID Vaccines and AA Risk, AA Rising Prevalence)

Evidence Based Hair

Play Episode Listen Later Nov 8, 2022 106:52


Studies in Androgenetic Alopecia and Alopecia Areata   STUDIES REFERENCED   MINOXIDIL CONCENTRATIONS   Singh et al (starts at 10:10). Does topical minoxidil at concentrations higher than 5% provide additional clinical benefit? Clin Exp Dermatol. 2022 Nov;47(11):1951-1955   Olsen EA, Dunlap FE, Funicella T et al (starts at 13:22). A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol 2002; 47: 377–85   McCoy J, Goren A, Kovacevic M, Shapiro J (starts at 16:02). Minoxidil dose response study in female pattern hair loss patients determined to be non-responders to 5% topical minoxidil. J Biol Regul Homeost Agents 2016;30: 1153–5   Goldust M (starts at 17:25). Minoxidil 15% solution versus minoxidil 5%solution in the treatment of androgenetic alopecia. Br JDermatol 2020;183(Suppl): 91 (abstract BH107)   Ghonemy S, Alarawi A, Bessar H (starts at 18:11). Efficacy and safety of a new 10% topical minoxidil versus 5% topical minoxidil and placebo in the treatment of male androgeneticalopecia: a trichoscopic evaluation. J Dermatolog Treat 2021;32: 236–41     JAK INHBITORS FOR ANDROGENETIC ALOPECIA   Casale F et al (starts at 22:19). Are Janus kinase (JAK) inhibitors beneficial in the treatment of androgenic alopecia? Int J Dermatol. 2022 Nov;61(11):e457-e458.   BOTOX FOR ANDROGENETIC ALOPECIA   English RS Jr and Ruiz S (starts at 29:30). Use of Botulinum Toxin for Androgenic Alopecia: A Systematic Review. Skin Appendage Disord. 2022 Mar;8(2):93-100   Shon U, Kim MH, Lee DY, Kim SH, Park BC (starts at 33:48). The effect of intradermal botulinum toxin on androgenetic alopecia and its possible mechanism. J Am Acad Dermatol. 2020 Dec;83(6):1838–9.     PLATELET RICH PLASMA TREATMENTS FOR ANDROGENETIC ALOPECIA Gupta AK and Bamimore M (starts at 39:09). Platelet-Rich Plasma Monotherapies for Androgenetic Alopecia: A Network Meta-Analysis and Meta-Regression Study. J Drugs Dermatol. 2022 Sep 1;21(9):943-952.   de Oliveira AFQ et al (starts at 42:25). Use of autologous platelet-rich plasma in androgenetic alopecia in women: a systematic review and meta-analysis. J Dermatolog Treat. 2022 Oct 31:1-11.   LOW DOSE ORAL MINOXIDIL SIDE EFFECTS   Dlova et al (starts 45:41). Pericardial, pleural effusion and anasarca: A rare complication of low-dose oral minoxidil for hair loss. JAAD Case Rep. 2022 Aug 11;28:94-96.   Randolph M, Tosti A (starts at 53:22). Oral minoxidil treatment for hair loss: a review of efficacy and safety. J Am Acad Dermatol. 2021;84(3): 737-746.     LOW DOSE ORAL MINOXIDIL EFFICACY AND SAFETY     Gupta AK et al (starts at 57:33). There Is a Positive Dose-Dependent Association between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings from a Systematic Review with Meta-Regression Analyses. Skin Appendage Disord. 2022 Sep; 8(5): 355–36     JAK INHIBITORS AND VENOUS THROMBOEMBOLISM Chen T-L et al (starts at 1:02:14). Association of Risk of Incident Venous Thromboembolism With Atopic Dermatitis and Treatment With Janus Kinase Inhibitors: A Systematic Review and Meta-analysis. JAMA Dermatol. 2022 Aug 24;e223516.   King B et al (1:05:33). Two Phase 3 Trials of Baricitinib for Alopecia Areata. N Engl J Med. 2022 Mar 26.   Misra D et al (starts at 1:11:19). Cardiovascular risks associated with Janus kinase inhibitors: peering outside the black box. Clin Rheumatol. 2022 Oct 20.     RISING PREVALENCE OF ALOPECIA AREATA IN JAPAN   Campos-Alberto E et al (starts at 1:13:00). Prevalence, comorbidities, and treatment patterns of Japanese patients with alopecia areata: A descriptive study using Japan medical data center claims database. J Dermatol. 2022 Nov 2.   COVID VACCINATION AND ALOPECIA AREATA RISK   Tassone F et al (starts at 1:15:21). Alopecia Areata Occurring after COVID-19 Vaccination: A Single-Center, Cross-Sectional Study. Vaccines (Basel). 2022 Sep 5;10(9):1467.   Nguyen B and Tosti A (starts at 1:21:22). Alopecia areata after COVID-19. J Eur Acad Dermatol Venereol. 2022 Aug 11;10.1111/jdv.18491.   Babadjouni  A et al (starts at 1:30:21). COVID-19 vaccination related exacerbations of hair loss in patients with moderate-to-severe alopecia areata on systemic therapy. JAAD Case Rep . 2022 Nov;29:181-185.   Chen C-H et al (starts at 1:36:55). Intractable alopecia areata following the second dose of COVID-19 vaccination: Report of two cases. Dermatol Ther. 2022 Sep;35(9):e15689.  

Evidence Based Hair
Season 3, Episode 3 (Resilience in AA, Hair Repigmentation and Melanoma, Accuracy of TikTok, Hair Straighteners & Uterine Cancer, Sebaceous Gland Atrophy in Seborrheic Dermatitis)

Evidence Based Hair

Play Episode Listen Later Oct 25, 2022 72:33


Recording of the Evidence Based Hair Podcast for the Oct 24, 2022 issue.    STUDIES REFERENCED Han JJ et al (starts at 5:28) Association of resilience and perceived stress in patients with alopecia areata: A cross-sectional study. J Am Acad Dermatol. 2022 Jul;87(1):151-153.   Gressler J et al (starts at 20:55 ). Re-pigmentation of scalp hair - A feature of early melanoma. Am J Med. 2022 Sep 25;S0002-9343(22)00711-2.   Lackey A et al (starts at 24:09) Repigmentation of gray hairs with lentigo maligna and response to topical imiquimod. JAAD Case Rep. 2019 Dec; 5(12): 1015–1017   Nguyen et al (starts at 27:18). Characterizing and assessing the reliability of TikTok's most viewed alopecia-related videos. J Eur Acad Dermatol Venereol. 2022 Aug 14.   Nagrani NS, Goldberg LJ (starts at 37:24). Sebaceous gland atrophy in seborrheic dermatitis of the scalp; a pilot study. J Cutan Pathol. 2022 Nov;49(11):988-992.   Headington JT, Gupta AK, Goldfarb MT, et al (starts at 41:26). A morphometric and histologic study of the scalp in psoriasis. Paradoxical sebaceous gland atrophy and decreased hair shaft diameters without alopecia. Arch Dermatol. 1989;125:639-642.   Klein EJ et al (starts at 46:38). Supplementation and hair growth: A retrospective chart review of patients with alopecia and laboratory abnormalities. JAAD Int. 2022 Aug 30;9:69-71.   Chang CJ et al (starts at 59:21). Use of Straighteners and Other Hair Products and Incident Uterine Cancer. J Natl Cancer Inst. 2022 Oct 17;djac165.

Medicine and Imaging
Hidradenite Supurativa

Medicine and Imaging

Play Episode Listen Later Sep 21, 2022 6:59


Referências1.Wortsman X, Moreno C, Soto R, Arellano J, Pezo C, Wortsman J. Ultrasound in-depth characterization and staging of hidradenitis suppurativa. Dermatol Surg. 2013;39(12):1835-42.2.Anduquia-Garay F, Rodriguez-Gutierrez MM, Poveda-Castillo IT, Valdes-Moreno PL, Agudelo-Rios DA, Benavides-Moreno JS, et al. Hidradenitis suppurativa: Basic considerations for its approach: A narrative review. Ann Med Surg (Lond). 2021;68:102679.3.Elkin K, Daveluy S, Avanaki KM. Hidradenitis suppurativa: Current understanding, diagnostic and surgical challenges, and developments in ultrasound application. Skin Res Technol. 2020;26(1):11-9.4.Wortsman X. Imaging of Hidradenitis Suppurativa. Dermatol Clin. 2016;34(1):59-68.5.Oranges T, Vitali S, Benincasa B, Izzetti R, Lencioni R, Caramella D, et al. Advanced evaluation of hidradenitis suppurativa with ultra-high frequency ultrasound: A promising tool for the diagnosis and monitoring of disease progression. Skin Res Technol. 2020;26(4):513-9.6.Martorell A, Wortsman X, Alfageme F, Roustan G, Arias-Santiago S, Catalano O, et al. Ultrasound Evaluation as a Complementary Test in Hidradenitis Suppurativa: Proposal of a Standarized Report. Dermatol Surg. 2017;43(8):1065-73.7.Wortsman X. Strong validation of ultrasound as an imaging biomarker in hidradenitis suppurativa. Br J Dermatol. 2021;184(4):591-2.8.Grand D, Frew JW, Navrazhina K, Krueger JG. Doppler ultrasound-based noninvasive biomarkers in hidradenitis suppurativa: evaluation of analytical and clinical validity. Br J Dermatol. 2021;184(4):688-96.9.Wortsman X, Castro A, Figueroa A. Color Doppler ultrasound assessment of morphology and types of fistulous tracts in hidradenitis suppurativa (HS). J Am Acad Dermatol. 2016;75(4):760-7.

Evidence Based Hair
Season 2, Episode 10 (Oral minoxidil, Hair Fibers, HCQ in Pregnancy, Teriflunomide-induced Hair Loss, Do it Yourself Haircare, Premature Greying of Hair)

Evidence Based Hair

Play Episode Listen Later Jul 29, 2022 95:36


ORAL MINOXIDIL IN PEDIATRICS   Jerjen R et al (starts at 12:33). Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome. Br J Dermatol. 2021;184(5):977-978. Nicolas-Ruanes et al (starts at 15:33). Low-dose oral minoxidil for treatment of androgenetic alopecia and telogen effluvium in a pediatric population: A descriptive study. J Am Acad Dermatol. 2022 Apr 26; John JM et al (starts at 17:24). Safety and tolerability of low-dose oral minoxidil in adolescents: A retrospective review. J Am Acad Dermatol . 2022 Jul 5;S0190-9622(22)02245-9.   HAIR FIBERS AND CAMOUFLAGE Ring and Keller (starts at 25:13). Effect of camouflaging agents on psychologic well-being: A cross-sectional survey of hair loss patients. J Am Acad Dermatol. 2017 Jun;76(6):1186-1189 Babadjouni A et al (starts at 28:15). Patient Satisfaction and Adverse Effects Following the use of Topical Hair Fiber Fillers. Int J Trichology. 2022 May-Jun; 14(3): 97–102   HYDROXYCHLOROQUINE IN PREGNANCY Reynolds JA et al (starts at 34:38). Outcomes of children born to mothers with systemic lupus erythematosus exposed to hydroxychloroquine or azathioprine. Rheumatology (Oxford). 2022 Jun 29: Sperber K et al (starts at 38:25). Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseases. Pediatr Rheumatol Online J 2009;7:9. Kaplan Y et al (starts at 39:17). Reproductive outcomes following hydroxychloroquine use for autoimmune diseases: a systematic review and meta-analysis. Br J Clin Pharmacol. 2016 May;81(5):835-48. Clowse MEB et al (starts at 40:27). Hydroxychloroquine in the pregnancies of women with lupus: a meta-analysis of individual participant data. Lupus Sci Med. 2022 Mar;9(1):e000651. Huybrechts K et al (starts at 42:37). Hydroxychloroquine early in pregnancy and risk of birth defects. Am J Obstet Gynecol 2021 Mar;224(3):290.e1-290.e22 Huybrechts K et al (starts at 45:20). Hydroxychloroquine early in pregnancy and risk of birth defects: absence of evidence is not the same as evidence of absence. Am J Obstet Gynecol. 2021 May;224(5):549-550. Bérard et al (starts at 46:58). Chloroquine and Hydroxychloroquine Use During Pregnancy and the Risk of Adverse Pregnancy Outcomes Using Real-World Evidence. Front Pharmacol. 2021 Aug 2;12:722511. Howley et al (starts at 47:17). Maternal exposure to hydroxychloroquine and birth defects. Birth Defects Res. 2021 Oct 15;113(17):1245-1256. Andersson et al (starts at 47:34). Fetal safety of chloroquine and hydroxychloroquine use during pregnancy: a nationwide cohort study. Rheumatology (Oxford). 2021 May 14;60(5):2317-2326.   TERIFLUNOMIDE INDUCED HAIR LOSS IN MULTIPLE SCLEROSIS Travis LH et al (starts at 53:28). Real-World Observational Evaluation of Hair Thinning in Patients with Multiple Sclerosis Receiving Teriflunomide: Is It an Issue in Clinical Practice? Neurol Ther. 2018 Dec; 7(2): 341–347. Porwal MH et al (starts at 55:41). Alopecia in Multiple Sclerosis Patients Treated with Disease Modifying Therapies. J Cent Nerv Syst Dis. 2022 Jun 23;14:11795735221109674.   DO IT YOURSELF LOW-ALLERGEN PRODUCTS Xiong M and Warshaw EM. (starts at 1:05:45) Hair Care Product Hacks: Do It Yourself Alternatives. Dermatitis. 2022 Jun 29. Zirwas M and Moennich J (starts at 1:00:25). Shampoos. Dermatitis. 2009 Mar-Apr;20(2):106-10 Tawfik M, Rodriguez-Homs LG, Alexander T, et al (starts at 1:01:10). Allergen content of  best-selling ethnic versus nonethnic shampoos, conditioners, and styling products. Dermatitis 2021;32(2):101–110 https://donovanmedical.com/diy   PREMATURE GREYING (EARLY CANITIES) Anggraini et al (starts at 1:08:50). Risk Factors Associated with Premature Hair Greying of Young Adult. Open Access Maced J Med Sci . 2019 Nov 14;7(22):3762-3764. Dawber RP (starts at 1:09:12). Integumentary associations of pernicious anaemia. Br J Dermatol . 1970 Mar;82(3):221-3. Mosley JG and Gibbs AC (starts at 1:09:50). Premature grey hair and hair loss among smokers: a new opportunity for health education? British Medical Journal 1996; 313: 1616. Bhat RM et al (starts at 1:10:21). Epidemiological and investigative study of premature graying of hair in higher secondary and pre-university school children. Int J Trichology. 2013;5:17–21. Chang H-C and Sung C-W (starts at 1:10:35). Association between serum levels of minerals and premature hair graying: a systematic review and meta-analysis. Int J Dermatol. 2020 Oct;59(10):e378-e380. Schnohr P et al (starts at 1:12:35). Longevity and gray hair, baldness, facial wrinkles, and arcus senilis in 13,000 men and women: The Copenhagen city heart study. J Gerontol A Biol Sci Med Sci. 1998;53:M347–50. Schnohr P et al. Gray hair, baldness, and wrinkles in relation to myocardial infarction: the Copenhagen City Heart Study. Am Heart J  1995 Nov;130(5):1003-10.   Kocaman SA et al (starts at 1:14:10) . The degree of premature hair graying as an independent risk marker for coronary artery disease: A predictor of biological age rather than chronological age. Anadolu Kardiyol Derg 2012;12:457-63.  Paik S et al (starts at 1:14:25). Association Between Premature Hair Greying and Metabolic Risk Factors: A Cross-sectional Study. Acta Derm Venereo. 2018 Aug 29;98(8):748-752. Mahendiratta S et al (starts at 1:15:09). Premature graying of hair: Risk factors, co-morbid conditions, pharmacotherapy and reversal-A systematic review and meta-analysis. Dermatol Ther. 2020 Nov;33(6):e13990. Das S et al (starts at 1:15:51) Cardiovascular risk markers in premature canities. Indian J Dermatol Venereol Leprol. 2022 Jun 30;1-5.

Evidence Based Hair
Season 2, Episode 9 (Isotretinoin and Finasteride for FFA, Eyelash Loss in FFA, Male FFA, LPP Incidence and Prevalence, CCCA Quality of Life)

Evidence Based Hair

Play Episode Listen Later Jul 21, 2022 63:33


FRONTAL FIBROSING ALOPECIA : ISOTRETINOIN VS FINASTERIDE Rakowska A, et al (starts at 9:15). Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases. J Drugs Dermatol. 2017. Rokni GR et al (starts at 10:43). Evaluating the combined efficacy of oral isotretinoin and topical tacrolimus versus oral finasteride and topical tacrolimus in frontal fibrosing alopecia - A randomized controlled trial. J Cosmet Dermatol. 2022 Jul 11.   FRONTAL FIBROSING ALOPECIA : EYELASH INVOLVEMENT Salas-Callo C et al (starts at 16:14). Eyelash involvement in frontal fibrosing alopecia: A prospective study. J Am Acad Dermatol 2022 Jul;87(1):232-234.   FRONTAL FIBROSING ALOPECIA : QUALITY OF LIFE David Saceda-Corralo et al (starts at 22:52). Health-Related Quality of Life in Patients With Frontal Fibrosing Alopecia. JAMA Dermatol. 2018 Apr 1;154(4):479-480. Varghae A et al (starts at 24:43). Assessment of health-related quality of life in patients with frontal fibrosing alopecia. J Cosmet Dermatol. 2022 Jun 27.   FRONTAL FIBROSING ALOPECIA : MALE FFA STUDIES OF ORAL MINOXIDIL AND FINASTERIDE/DUTASTERIDE Moussa A et al (starts at 30:00). Clinical features and treatment outcomes of frontal fibrosing alopecia in men. Int J Dermatol. 2022 Jun 21 LPP PREVALENCE STUDIES Trager MH et al (starts at 40:50). Prevalence estimates for lichen planopilaris and frontal fibrosing alopecia in a New York City health care system. J Am Acad Dermatol 2021 Apr;84(4):1166-1169 Lavian J et al (starts at 41:37). Incidence estimates for lichen planopilaris and frontal fibrosing alopecia in a New York City health care system.Dermatol Online J. 2021 Aug 15;27(8). Lim S H et al (starts at 42:29). Rapidly increasing incidence and prevalence of lichen planopilaris in an Asian population: A Korean nationwide population-based study. J Dermatol. 2022 Jun 21. Joshi TP et al (starts at 49:10). Prevalence of lichen planopilaris in the United States: A cross-sectional study of the All of Us research program. JAAD Int. 2022 Jun 13;8:69-70   CENTRAL CENTRIFUGAL CICATRICIAL ALOPECIA: QUALITY OF LIFE Akintilo et al (starts at 54:48). Health care barriers and quality of life in central centrifugal cicatricial alopecia patients. Cutis. 2018 Dec;102(6):427-432.   Maranga et al (starts at 56:49). Quality of life in patients with central centrifugal cicatricial alopecia: a preliminary study. Br J Dermatol. 2022 Jun 15.     CONCLUSION AND SUMMARY - starts at 58:46

Evidence Based Hair
Season 2, Episode 8 (COVID shedding, Trichotillomania, Traction Alopecia, Tinea Capitis Carrier State)

Evidence Based Hair

Play Episode Listen Later Jul 11, 2022 53:22


STUDIES REFERENCED   COVID RELATED SHEDDING   Mazeto IFS et al (starts at 6:09). Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20.   Czech T et al (starts at 14:30). Characteristics of Hair Loss after COVID-19: Systematic Scoping Review. J Cosmet Dermatol. 2022 Jul 8.     TRICTHOTILLOMANIA   Thomson H et al (starts at 24:58). Prevalence and gender distribution of trichotillomania: A systematic review and meta-analysis. J Psychiatr Res. 2022 Jul 1;153:73-81.   TINEA CAPITIS     Lecerf P et al (starts at 30:10). Asymptomatic Scalp Carriage among Household Contacts of Children Affected by Tinea Capitis: A Prospective Study in the Metropolitan Area of Brussels, Belgium.  Skin Appendage Disord. 2022 May;8(3):200-205.   TRACTION ALOPECIA   Lucia GS et al (starts at 42:30). Traction alopecia: Neglected in women and children of color. J Am Acad Dermatol. 2022 May 28;   FINAL COMMENTS AND SUMMARY - starts at 49:03

Evidence Based Hair
Season 2, Episode 7 (AGA and Smoking, Alopecia Areata and Eye Diseases, MTX for Pediatric AA, Upadacitinib for AA)

Evidence Based Hair

Play Episode Listen Later Jul 4, 2022 44:02


Kavadya T and Mysore V (starts at 5:24). Role of Smoking in Androgenetic Alopecia: A Systematic Review. Int J Trichology. 2022 Mar-Apr; 14(2): 41–48.   Mosley JG and Gibbs AC (starts at 6;30). Premature grey hair and hair loss among smokers: a new opportunity for heatlh education? British Medical Journal 1996; 313: 1616.   Su LH and Chen T H-H (starts at 7:38) Association of Androgenetic Alopecia with Smoking and Its Prevalence Among Asian Men. Archives of Dermatology 2007 143; 1401-1406.       Calvao J et al (starts at 9:16). Finasteride and Floppy Iris Syndrome: What Role Can the Dermatologist Play? Int J Trichology. May-Jun 2022;14(3):115-116.   Ting H-C et al (starts at 14:04). Association between alopecia areata and retinal diseases: A nationwide population-based cohort study. J Am Acad Dermatol . 2021 Nov 1;S0190-9622(21)02735-3.   Thatiparthi A et al (starts at 15:56). Inflammatory ocular comorbidities in alopecia areata: a retrospective cohort study of a single academic center. J Am Acad Dermatol. 2022 Jun 16;S0190-9622(22)01009-X     Albela H et al (starts at 19:32). Efficacy and Tolerability of Methotrexate in the Treatment of Severe Paediatric Alopecia Areata. Skin Appendage Disord. 2022 May;8(3):206-210.     Barton V et al (starts at 24:20). Treatment of pediatric alopecia areata: A systematic review. J Am Acad Dermatol. 2022 Jun;86(6):1318-1334.     Gambardella A, et al (starts at 29:18). Dual Efficacy of Upadacitinib in 2 Patients With Concomitant Severe Atopic Dermatitis and Alopecia Areata. Dermatitis 2021; 32: e85–e86.   Cantelli M et al (starts at 31:35). Upadacitinib improved alopecia areata in a patient with atopic dermatitis: a case report. Dermatol Ther. 2022; 1: e15346    Asfour et al (starts at 32:35). Concurrent chronic alopecia areata and severe atopic dermatitis successfully treated with upadacitinib.  Int J Dermatol. 2022 Jun 20.   Gori N et al (starts at 33:53). Assessment of alopecia areata universalis successfully treated with upadacitinib. Int J Dermatol. 2022 Jul 2.     Conclusions and Summary (starts at 37:24)

Evidence Based Hair
Season 2, Episode 4 (SSRI's, COVID 19, iron, traction, trichotillomania)

Evidence Based Hair

Play Episode Listen Later Jun 14, 2022 54:08


DYSTROPHIC ANAGEN EFFLUVIUM IN COVID 19 SHEDDING Shanshal M (start 7:52). COVID-19 related anagen effluvium. J Dermatolog Treat. 2022 Mar;33(2):1114-1115. Anna Carolina Miola et al (starts 9:45). Early-onset effluvium secondary to COVID-19: Clinical and histologic characterization. J Am Acad Dermatol. 2022   ALTERNATE DAY IRON DOSING Lale Aydın Kaynar et al (starts 12:57). Comparison of daily oral iron replacement therapy with every other day treatment in female reproductive age patients with iron-deficiency anemia. Ann Hematol. 2022 Apr 23. Stoffel NU et al (starts 17:23). Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials. Lancet Haematol. 2017 Nov;4(11):e524-e533. Mehta S et al (starts 19:03). A Prospective, Randomized, Interventional Study of Oral Iron Supplementation Comparing Daily Dose with Alternate Day Regimen Using Hepcidin as a Biomarker in Iron Deficiency Anemia. J Assoc Physicians India. 2020 May;68(5):39-41.   INTRAVENOUS IRON Aratsu et al (starts 22:57). Analysis of Adverse Events and Intravenous Iron Infusion Formulations in Adults With and Without Prior Infusion Reactions. JAMA Netw Open. 2022 Mar; 5(3): e224488.   SSRI AND HAIR LOSS Etiman M et al (starts 29:44). Risk of hair loss with different antidepressants: a comparative retrospective cohort study. Int Clin Psychopharmacol 2018 Jan;33(1):44-48. Pejcic and Paudel (starts 31:17). Alopecia associated with the use of selective serotonin reuptake inhibitors: Systematic review. Psychiatry Res. 2022 May 10;313:114620. ;86(5):e207-e208.   TRACTION ALOPECIA Beach RA (starts 35:56). Case series of oral minoxidil for androgenetic and traction alopecia: Tolerability & the five C's of oral therapy. Dermatol Ther. 2018 Nov;31(6):e12707. Kim and Craiglow (starts 36:38). Treatment of traction alopecia with oral minoxidil. JAAD Case Rep. 2022 Apr 1;23:112-113.   N ACETYL CYSTEINE IN TRICHOTILLOMANIA Grant JE et al (starts 44:20). Arch Gen Psychiatry 2009 Bloch MH et al (starts 46:05) N-Acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial. J Am Acad Child Adolesc Psychiatry. 2013 Mar;52(3):231-40. Popova L and Mancuso J (starts 48:09). Dramatic Improvement of Trichotillomania with 6 Months of Treatment With N-Acetylcysteine. Glob Pediatr Health. 2022 Mar 14;9:2333794X221086576.

Evidence Based Hair
Season 2, Episode 3 (Oral minoxidil in males, dutasteride microneedling, sleep disturbances in AGA, endothelial dysfunction in alopecia areata, pediatric alopecia areata)

Evidence Based Hair

Play Episode Listen Later Jun 7, 2022 59:44


ANDROGENETIC ALOPECIA STUDIES Sanabria et al (starts at 4:40). Prospective cardiovascular evaluation with 24-h Holter and 24-h ambulatory blood pressure monitoring in men using 5 mg oral minoxidil for androgenetic alopecia. J Am Acad Dermatol. 2022 May 18; Klein E et al (starts at 13:40). Comparing combination low-dose oral minoxidil and topical minoxidil with oral minoxidil alone for the treatment of non-scarring alopecia; a retrospective chart review. J Cosmet Dermatol. 2022 Jun 1. Cao L et al (starts at 21:19). Nailfold capillaroscopy alterations in androgenetic alopecia: A cross-sectional study. Indian J Dermatol Venereol Leprol. 2022 Feb 28;1-7. doi: 10.25259/IJDVL_714_2021. Emmanuel Sánchez-Meza et al (starts at 28:17). Microneedling plus topical dutasteride solution for androgenetic alopecia: a randomized placebo-controlled study. J Eur Acad Dermatol Venereol. 2022 Jun 1. doi: 10.1111/jdv.18285.  David Saceda-Corralo et al. Mesotherapy with Dutasteride in the Treatment of Androgenetic Alopecia. Int J Trichology. 2017 Jul-Sep; 9(3): 143–145. Liamsombut S et al (starts at 34:45). Sleep quality in men with androgenetic alopecia. Sleep and Breathing. 2022 Apr 25.     ALOPECIA AREATA STUDIES Anna Waśkiel-Burnat et al (starts at 41:33). Patients with alopecia areata are at risk of endothelial dysfunction: results of a case-control study. Clin Exp Dermatol. 2022 Mar 31. Conic et al. Prevalence of cardiac and metabolic diseases among patients with alopecia areata.J Eur Acad Dermatol Venereol . 2021 Feb;35(2):e128-e129. Youssef S et al (starts at 48:28). Tofacitinib Therapy for Alopecia Areata is not Associated with Adverse Events during COVID-19 Infection. J Am Acad Dermatol. 2022 May 9;S0190-9622(22)00795-2. McKenzie P et al (starts at 53:32). Evaluation of the Prevalence and Incidence of Pediatric Alopecia Areata Using Electronic Health Record Data. JAMA Dermatol. 2022 May 1;158(5):547-551.

Evidence Based Hair
Season 2, Episode 2 (Oral Minoxidil, Sarcoidosis, JAK inhibitor safety and Trichomegaly)

Evidence Based Hair

Play Episode Listen Later May 24, 2022 68:51


Recording of the Evidence Based Hair Podcast for the May 23, 2022 issue.  ORAL MINOXIDIL USE IN PEDIATRIC PATIENTS   Nicolas-Ruanes et al (starts at 4:00). Low-dose oral minoxidil for treatment of androgenetic alopecia and telogen effluvium in a pediatric population: A descriptive study. J Am Acad Dermatol. 2022 Apr 26;   Jerjen R et al. Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome. Br J Dermatol. 2021;184(5):977-978.     ORAL MINOXIDIL COMPOUNDING ERRORS   Moreno-Arrones OM et al (starts at 9:06). Serious Adverse effects From Compounding Errors With Low-Dose Oral Minoxidil for Alopecia Treatment. Actas Dermosifiliogr. 2022 May 12;S0001-7310(22)00414-8.     DOXYCYCLINE SKIN PIGMENTATION   Afrin et al (starts at 17:15). Doxycycline-Associated Hyperpigmentation: A Case Report and Literature Review. Cureus.  2022 Apr 2;14(4):e23754.     SCALP SARCOIDOSIS Kim JC and Lee ES (starts at 22:06). Unusual Case of Scalp Sarcoidosis with Alopecia: An Only Manifestation of Cutaneous Sarcoidosis without Systemic Involvement. Ann Dermatol. 2022 Apr;34(2):154-156.   Long T et al. Severe scalp sarcoidosis in an unlikely patient. JAAD Case Rep. 2020 Apr 24;6(11):1165-1166.   House NS et al. Sarcoidosis-induced alopecia.Dermatol Online J 2012 Aug 15;18(8):4.     Ghosh A et al. Single lesion of sarcoidosis presenting as cicatricial alopecia: a rare report from India. Int J Trichology . 2014 Apr;6(2):63-6.   Prohaska J et al. Scalp Sarcoidosis Presenting as Cicatricial Alopecia. J Am Osteopath Assoc.  2018 Dec 1;118(12):824-826.    Conde K et al. Lupus Pernio in Chronic Sarcoidosis. Cureus 2021 Sep; 13(9): e18331.   Hubail et al. Lupus pernio (Besnier-Tenneson syndrome): A rare form of sarcoidosis. Dermatol Reports 2018 Oct 1; 10(2): 7696.   Gopikrishnan Anjaneyan and Rita Vora Lupus pernio without systemic involvement. Indian Dermatol Online J. 2013 Oct-Dec; 4(4): 314–317.   JAK INHIBITOR SAFETY Hoisnard L et al (starts at 37:53). Adverse events associated with JAK inhibitors in 126,815 reports from the WHO pharmacovigilance database. Sci Rep. 2022 May 3;12(1):7140   EYELASH TRICHOMEGALY WITH EGFR INHIBITORS Inamadar S and Kumar NSP (starts at 59:03). Lady with Long Eyelashes… Int J Trichology. Mar-Apr 2022;14(2):71-72. 

THE DESI EM PROJECT
DESI EM PROJECT - EPISODE 11 - THE ONE WITH "MYTHS IN EMERGENCY MEDICINE PART 2"

THE DESI EM PROJECT

Play Episode Listen Later May 15, 2022 7:26


In this episode of myths in emergency medicine, I talk about Oxygen in STEMI patients, Epinephrine in digital anaesthesia, C- line for CVP monitoring and MILS in trauma patients. You can go through some of the following papers and decide what you want to do with your EM practice - 1. Stub D, Smith K, Bernard S, Nehme Z, Stephenson M, Bray JE, Cameron P, Barger B, Ellims AH, Taylor AJ, Meredith IT, Kaye DM; AVOID Investigators. Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction. Circulation. 2015 Jun 16;131(24):2143-50. doi: 10.1161/CIRCULATIONAHA.114.014494. Epub 2015 May 22. PMID: 26002889. 2. Hofmann R, Befekadu Abebe T, Herlitz J, James SK, Erlinge D, Yndigegn T, Alfredsson J, Kellerth T, Ravn-Fischer A, Völz S, Lauermann J, Jernberg T, Lindahl B, Langenskiöld S. Routine Oxygen Therapy Does Not Improve Health-Related Quality of Life in Patients With Acute Myocardial Infarction-Insights From the Randomized DETO2X-AMI Trial. Front Cardiovasc Med. 2021 Mar 15;8:638829. doi: 10.3389/fcvm.2021.638829. PMID: 33791349; PMCID: PMC8006541. 3. Krunic AL, Wang LC, Soltani K, Weitzul S, Taylor RS. Digital anesthesia with epinephrine: an old myth revisited. J Am Acad Dermatol. 2004 Nov;51(5):755-9. doi: 10.1016/j.jaad.2004.05.028. PMID: 15523354. 4. Mohan, P P. “Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Epinephrine in digital nerve block.” Emergency medicine journal : EMJ vol. 24,11 (2007): 789-90. doi:10.1136/emj.2007.053793 5. Marik PE, Baram M, Vahid B. Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares. Chest. 2008 Jul;134(1):172-8. doi: 10.1378/chest.07-2331. PMID: 18628220. 6. Ellis DY, Harris T, Zideman D. Cricoid pressure in emergency department rapid sequence tracheal intubations: a risk-benefit analysis. Ann Emerg Med. 2007 Dec;50(6):653-65. doi: 10.1016/j.annemergmed.2007.05.006. Epub 2007 Aug 3. PMID: 17681642. 7. Santoni BG, Hindman BJ, Puttlitz CM, Weeks JB, Johnson N, Maktabi MA, Todd MM. Manual in-line stabilization increases pressures applied by the laryngoscope blade during direct laryngoscopy and orotracheal intubation. Anesthesiology. 2009 Jan;110(1):24-31. doi: 10.1097/ALN.0b013e318190b556. PMID: 19104166. 8. Manoach S, Paladino L. Manual in-line stabilization for acute airway management of suspected cervical spine injury: historical review and current questions. Ann Emerg Med. 2007 Sep;50(3):236-45. doi: 10.1016/j.annemergmed.2007.01.009. Epub 2007 Mar 6. PMID: 17337093. 9. Wiles MD. Manual in-line stabilisation during tracheal intubation: effective protection or harmful dogma? Anaesthesia. 2021 Jun;76(6):850-853. doi: 10.1111/anae.15472. PMID: 33939842.

Evidence Based Hair
Evidence Based Hair Season 1, Episode 12 (Season 1 Finale; Scalp Allergic Contact Dermatitis, PDL laser induced hair loss, Plaquenil Oral Pigmentation, Persistent Chemotherapy Induced Alopecia)

Evidence Based Hair

Play Episode Listen Later Apr 26, 2022 68:49


Recording of the Evidence Based Hair Podcast for the April 25, 2022 issue.   STUDIES REFERENCED   ALLERGIC CONTACT DERMATITIS STUDIES Feryel A et al (starts at 3:51). Unusual clinical presentation of allergic contact dermatitis to topical minoxidil. Contact Dermatitis. 2022 Mar 28 Pham et al (starts at 12:18). Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens. Dermatitis. 2022 Mar 22.   PULSED DYE LASER AND HAIR LOSS IN INFANTILE HEMANGIOMAS Yang et al (starts at 19:56). Risk factors of long-term alopecia after pulsed-dye laser treatment for infantile scalp hemangiomas: A retrospective study. J Dermatol. 2022 Apr 5. Feldstein S et al. Can long-term alopecia occur after appropriate pulsed-dye laser therapy in hair-bearing sites? Pediatric dermatologists weigh in. Dermatol Surg. 2015 Mar;41(3):348-51.   ORAL PIGMENTATION FROM HYDROXYCHLOROQUINE Silva PUJ et al (starts at 31:26). Oral pigmentation as an adverse effect of chloroquine and hydroxychloroquine use: A scoping review. Medicine (Baltimore). 2022 Mar 18;101(11):e29044.   PERMANENT CHEMOTHERAPY INDUCED ALOPECIA Lyakhovitsky A et al (starts at 37:38). Permanent chemotherapy-induced alopecia after hematopoietic stem cell transplantation treated with low-dose oral minoxidil. JAAD Case Rep. 2022 Feb 17;22:64-67. Vano-Galvan S et al. Safety of low dose oral minoxidil for hair loss: A multicenter study of 1404 patients. JAAD 2021; 84: 1644-51. Sanabria B et al. Adverse effects of low dose oral minoxidil for androgenetic alopecia in 435 patients. JAAD 2021; 84: 1175-78. Kolla et al (starts at 54:24). Permanent chemotherapy-induced alopecia presenting with erosive pustular dermatosis-like retention hyperkeratosis. JAAD Case Rep. 2022 Jan 6;21:77-79. Yin et al (starts at 58:25). Dermatologist Awareness of Scalp Cooling for Chemotherapy-induced Alopecia. J Am Acad Dermatol. 2022 Mar 9;S0190-9622(22)00386-3  

Evidence Based Hair
Season 1, Episode 11 (Scarring Alopecia - Frontal Fibrosing Alopecia and Lichen Planopilaris)

Evidence Based Hair

Play Episode Listen Later Apr 18, 2022 50:14


STUDIES REFERENCED FRONTAL FIBROSING ALOPECIA & REPIGMENTATION: Barreto TM et al (starts at 3:18). Atypical frontal fibrosing alopecia presentation in a male patient associated with spontaneous reversal of canities. J Eur Acad Dermatol Venereol. 2022 Mar 12 Defo D et al Repigmentation pilaire enbordure d'une alopecie frontale fibrosante. [Hair darkening close to a patch of frontal fibrosing alopecia]. Ann Dermatol Venereol 2006;133: 799–801 Pastor-Nieto et al. Localized grey hair repigmentation (canities reversal) in patients with frontal fibrosing alopecia. J Eur Acad Dermatol Venereol 2021; 35: e408–e410.   COSMETIC SURGERY AND RISK OF FRONTAL FIBROSING ALOPECIA: Pham et al (starts at 9:00). The Association of Frontal Alopecia with a History of Facial and Scalp Surgical Procedures. Skin Appendage Disord. 2022 Jan;8(1):13-19. Kossard and Shiell. Frontal fibrosing alopecia developing after hair transplantation for androgenetic alopecia. Int J Dermatol. 2005 Apr;44(4):321-3. Chiang YZ et al. Lichen planopilaris following hair transplantation and face-lift surgery Br J Dermatol. 2012 Mar;166(3):666-370.   HAIR TRANSPLANT SURGERY FOR PATIENTS WITH FFA: Vano-Galvan S et al (starts at 14:30). Hair transplant in frontal fibrosing alopecia: A multicenter review of 51 patients. J Am Acad Dermatol. 2019 Sep;81(3):865-866. Arasu et al (starts at 22:13). Scalp reduction surgery does not reactivate frontal fibrosing alopecia: A case report. Dermatol Ther. 2022 Mar 16;e15451.   LICHEN PLANOPILARIS AND CHECKPOINT INHIBITORS Garcia-Melendo C et al (starts at 38:59). Extensive lichen planopilaris as exclusive lichenoid reaction secondary to pembrolizumab in a patient with metastatic melanoma. Dermatol Ther. 2022 Feb 17;e15388. Uthayakumar AK et al. Severe progressive scarring pembrolizumab-induced lichen planopilaris in a patient with metastatic melanoma. Australas J Dermatol. 2021 Aug;62(3):403-406. Cogen et al. Lichen planopilaris associated with pembrolizumab in a patient with metastatic melanoma. JAAD Case Rep . 2018 Jan 16;4(2):132-134. Dominguez-Santas M et al. Avelumab-induced lichen planopilaris, a novel association. Int J Dermatol. 2021 Oct;60(10):e414-e416.

Evidence Based Hair
Evidence Based Hair - Season 1, Episode 10 (Telogen Effluvium, Tinea Capitis, Trichotillomania)

Evidence Based Hair

Play Episode Listen Later Apr 11, 2022 54:12


REFERENCES CITED IN THIS EPISODE (and TIME STAMP)   TELOGEN EFFLUVIUM   Monari et al (starts at 4:20). Post-SARS-CoV-2 Acute Telogen Effluvium: An Expected Complication. J Clin Med. 2022 Feb 24;11(5):1234. Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26. Guarnieri G et al (starts at 9:07). Relationship between hair shedding and systemic inflammation in COVID-19 pneumonia. Ann Med. 2022;54(1):869-874. Wong-Chew RM et al (starts at 13:11). Symptom cluster analysis of long COVID-19 in patients discharged from the Temporary COVID-19 Hospital in Mexico City. Ther Adv Infect Dis. 2022 Jan 11;9:20499361211069264. Fernandez-de-Las-Penas et al. Female Sex Is a Risk Factor Associated with Long-Term Post-COVID Related-Symptoms but Not with COVID-19 Symptoms: The LONG-COVID-EXP-CM Multicenter Study. J Clin Med. 2022 Jan 14;11(2):413. Ali MD (starts at 18:49). Proton pump inhibitors' use and risk of iron deficiency anaemia: a systematic review and meta-analysis. Curr Rev Clin Exp Pharmacol. 2022 Mar 7.      TRICHOTILLOMANIA AND PEDIATRIC EMOTIONAL HEALTH Wang et al (starts at 24:29). Trichotillomania occurs during the COVID-19 pandemic in an adolescent. World J Pediatr. 2022 Feb 28;1-2. Saunders NR et al. Utilization of Physician-Based Mental Health Care Services Among Children and Adolescents Before and During the COVID-19 Pandemic in Ontario, Canada. April 2022 JAMA Pediatrics.2022 Apr 1;176(4):e216298. Racine  N et al. Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19: A Meta-analysis JAMA Pediatr. 2021;175(11):1142-1150. Pathoulas et al. Cross-sectional survey examining skin picking and hair pulling disorders during the COVID-19 pandemic. J Am Acad Dermatol. 2021 Mar;84(3):771-773. Öner Ü. Children with trichotillomania in COVID-19 outbreak. J Cosmet Dermatol. 2021;20(7):1967–8.     TINEA CAPITIS Salah NB et al (starts at 31:19). Erythema nodosum in patients with kerion of scalp. Clin Exp Dermatol. 2021 Dec;46(8):1577-1578. Blake T et al. Erythema nodosum - a review of an uncommon panniculitis. Dermatol Online J. 2014 Apr 16;20(4):22376. Kumar P and Pandhi D (starts at 41:09). Role of Trichoscopy in the Management of Tinea Capitis in Two  Infants: A Case Report. J Cutan Aesthet Surg. Oct-Dec 2021;14(4):443-445.  

Evidence Based Hair
Evidence Based Hair - Season 1, Episode 9 (Alopecia Areata and Androgenetic Alopecia)

Evidence Based Hair

Play Episode Listen Later Apr 4, 2022 46:57


STUDIES HIGHLIGHTED ALOPECIA AREATA King B et al (starts at 3:27). Two Phase 3 Trials of Baricitinib for Alopecia Areata. N Engl J Med. 2022 Mar 26. Fenentinos P et al (starts at 16:24). Assessing the role of stressful life events in the induction and recurrence of alopecia areata: a case-control study. J Am Acad Dermatol.  2022 Mar 24;S0190-9622(22)00526-6. Macbeth A et al (starts at 21:14). The associated burden of mental health     conditions in alopecia areata: A population-based study in UK primary care. Br J Dermatol.  2022 Feb 14. Senna M et al (starts at 29:06). Predictors of Quality of Life in Patients with Alopecia Areata. J Invest Dermatol 2022 Mar 21;S0022-202X     ANDROGENETIC ALOPECIA Ghafoor R et al (starts at 39:15). Association of androgenetic alopecia and severity of coronavirus disease 2019. J Cosmet Dermatol. 2022 Mar;21(3):874-879. Baghani M et al (starts at 40:57). Androgenetic alopecia and COVID-19: Is there a clinical connection? J Cosmet Dermatol . 2022 Feb;21(2):420-425. Veskovic D et al (starts at 42:04). Association of androgenetic alopecia with a more severe form of COVID-19 infection. Ir J Med Sci. 2022 Mar 23;1-6.  

Evidence Based Hair
Evidence Based Hair - Season 1, Episode 7 (Scarring Alopecia)

Evidence Based Hair

Play Episode Listen Later Mar 21, 2022 53:43


STUDIES HIGHLIGHTED FFA STUDIES Dubin C et al (starts at 2:50). Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016 Starace et al (starts at 12:31). Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results From a Multicenter Study of the International Dermoscopy Society. Dermatol Pract Concept. 2022 Jan 1;12(1):e2022080 Rayinda T et al (starts at 17:25). Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK. Br J Dermatol. 2022 Jan;186:195-197   LPP STUDIES Moussa A et al (starts at 21:51). Treatment of lichen planopilaris with baricitinib: A retrospective study. J Am Acad Dermatol. 2022 Feb 21;S0190-9622(22)00338-3 Mostafa N et al (starts at 25:24). Mycophenolate mofetil and lichen planopilaris: systematic review and meta-analysis. J Dermatolog Treat . 2022 Feb;33(1):369-372.   FOLLICULITIS DECALVANS STUDIES Iorizzo M et al (starts at 27:25). Refractory folliculitis decalvans treated with adalimumab: a case series of 23 patients. J Am Acad Dermatol 2022 Mar 1;S0190-9622(22)00358-9.   CCCA STUDIES Roche FC et al (starts at 33:01). Association of type 2 diabetes with central centrifugal cicatricial alopecia: A follow-up study. J Am Acad Dermatol. 2022 Mar;86(3):661-662. Collins MS et al (starts at 37:45). Increased risk of vitamin D deficiency and insufficiency in Black patients with central centrifugal cicatricial alopecia. J Am Acad Dermatol . 2022 Feb 15;S0190-9622(22)00272-9. Powe et al.  Vitamin D-binding protein and vitamin D status of black Americans and white Americans. N Engl J Med 2013 Nov 21;369(21):1991-2000. Brown L et al. The vitamin D paradox in Black Americans: a systems-based approach to investigating clinical practice, research, and public health - expert panel meeting report. BMC Proc . 2018 May 9;12(Suppl 6):6.    

The Visible Voices
Jenna Lester and Susan Chon Skin Color and Representation in Dermatology

The Visible Voices

Play Episode Listen Later Mar 4, 2022 36:57


We Need More Illustrations of People of Color in Medical Textbooks— The lack of diversity perpetuates health inequality and stereotypes "The consequences of primarily depicting White, lighter skinned individuals with Eurocentric features in medical images supports the persuasive concept of White supremacy. It perpetuates the belief that the White male body is "the standard" to which all other bodies should be compared. It leads to inequality in medical education and further perpetuates harmful stereotypes of Black individuals. As a result, this issue plays a role in inappropriate diagnosis and health management of Black individuals. Furthermore, medical care becomes subjective, discriminatory, and filled with speculatory assumptions based on stereotypes." Jenna C. Lester is founder of the Skin of Color dermatology program at UCSF, which addresses the  persistent issues that arise from the exclusion and marginalization of non-white patients in medical  research and practice. She is combatting medical disparities due to racial inequality, working to fill education gaps in textbooks and curriculum about non-white skin and training a new generation of  doctors. A graduate of Harvard University and The Warren Alpert Medical School of Brown University, she is an assistant professor of dermatology at UCSF where she practices and teaches general dermatology. Jenna's TedX Talk Susan Y. Chon, a 1991 Brown graduate with an independent concentration in children's literature, is a professor in the Department of Dermatology at the University of Texas M.D. Anderson Cancer Center. Prior to joining the faculty, she earned her M.D. from Stanford University School of Medicine. She then completed her internship in internal medicine and her dermatology residency at Stanford University Hospital. Chon specializes in treating patients with skin cancers, melanomas and skin disorders from cancer treatments. She is a medical educator and an active mentor for medical students and dermatology residents. She is also director of the Skin Cancer Screening and Prevention Program and founded the volunteer physician program for the Brookwood Community, a residential and vocational program for adults with disabilities. Chon is the president of the Brown Club of Houston, helping to maintain the connection between Brown and its graduates throughout the world, and serves as a member of the Women's Leadership Council, Women's Launch Pad and Philanthropy Advisory Group.  Under-representation of skin of colour in dermatology images: not just an educational issue.Lester JC, Taylor SC, Chren MM.Br J Dermatol. 2019 Jun;180(6):1521-1522. doi: 10.1111/bjd.17608.PMID: 31157429 No abstract available.  Clinical photography in skin of colour: tips and best practices.Lester JC, Clark L Jr, Linos E, Daneshjou R.Br J Dermatol. 2021 Jun;184(6):1177-1179. doi: 10.1111/bjd.19811. Epub 2021 Mar 18.PMID: 33448346 No abstract available.  Integrating skin of color and sexual and gender minority content into dermatology residency curricula: A prospective program initiative.Jia JL, Gordon JS, Lester JC, Linos E, Nord KM, Bailey EE.J Am Acad Dermatol. 2021 Apr 16:S0190-9622(21)00816-1. doi: 10.1016/j.jaad.2021.04.018. Online ahead of print.PMID: 33872717 No abstract available. Two pandemics: Opportunities for diversity, equity and inclusion in dermatology.Lester JC, Taylorf SC.Int J Womens Dermatol. 2021 Jan 17;7(2):137-138. doi: 10.1016/j.ijwd.2021.01.015. eCollection 2021 Mar.PMID: 33937478 Free PMC article. No abstract available. Encouraging the next generation of skin of color researchers: Funding skin of color research in medical school and residency.Jia JL, Amuzie AU, Lester JC.J Am Acad Dermatol. 2021 Sep;85(3):e161-e163. doi: 10.1016/j.jaad.2020.11.048. Epub 2020 Nov 27.PMID: 33253843 No abstract available. Skin Cancer in People of Color: A Systematic Review.Zakhem GA, Pulavarty AN, Lester JC, Stevenson ML.Am J Clin Dermatol. 2021 Dec 13. doi: 10.1007/s40257-021-00662-z. Online ahead of print.PMID: 34902111BACKGROUND: People of African, Asian, Hispanic or Latino, Pacific Islander, and Native Indian descent are considered people of color by the Skin of Color Society (SOCS). OBJECTIVES: In this study, we assess incidence, risk factors, clinical characteristics, histopathology,  Skin-of-color article representation in dermatology literature 2009-2019: Higher citation counts and opportunities for inclusion.Amuzie AU, Jia JL, Taylor SC, Lester JC.J Am Acad Dermatol. 2021 Mar 24:S0190-9622(21)00617-4. doi: 10.1016/j.jaad.2021.03.063. Online ahead of print.PMID: 33771597 No abstract available. Establishing the diagnosis of rosacea in skin of color patients.Onalaja AA, Lester JC, Taylor SC.Cutis. 2019 Jul;104(1):38-41.PMID: 31487335Rosacea is a chronic inflammatory cutaneous disorder that may be underreported and underrecognized in skin of color (SOC) patients. There are several skin disorders that can present with the classic features of rosacea, such as erythema, papules, and pustules, which … Absence of images of skin of colour in publications of COVID-19 skin manifestations.Lester JC, Jia JL, Zhang L, Okoye GA, Linos E.Br J Dermatol. 2020 Sep;183(3):593-595. doi: 10.1111/bjd.19258. Epub 2020 Jul 16.PMID: 32471009 Free PMC article.Mounting evidence shows that COVID-19 impacts several organ systems, including the s

2 View: Emergency Medicine PAs & NPs
14 - Urticaria, Foreign Bodies, and a Special Interview

2 View: Emergency Medicine PAs & NPs

Play Episode Listen Later Feb 27, 2022 93:11


Welcome to Episode 14 of “The 2 View,” the podcast for EM and urgent care nurse practitioners and physician assistants! Show Notes for Episode 14 of “The 2 View” – Urticaria, Foreign Bodies, and a Special Interview Urticaria Bernstein JA, Lang DM, Khan DA, et al. The diagnosis and management of acute and chronic urticaria: 2014 update. J Allergy Clin Immunol. Published 2014. Accessed February 11, 2022. https://www.aaaai.org/Aaaai/media/MediaLibrary/PDF%20Documents/Practice%20and%20Parameters/Urticaria-2014.pdf Radecki RP, MS. Does New IV Urticaria Medication Offer Benefits Over Current Treatments? ACEP Now. Published June 15, 2021. Accessed February 11, 2022. https://www.acepnow.com/article/does-new-iv-urticaria-medication-offer-benefits-over-current-treatments/ Safety of use of high dose antihistamines in difficult-to-control chronic urticaria patients. J Am Acad Dermatol. Published May 1, 2015. Accessed February 11, 2022. https://www.jaad.org/article/S0190-9622(15)00371-0/fulltext Sarti L, Barni S, Giovannini M, Liccioli G, Novembre E, Mori F. Efficacy and tolerability of the updosing of second-generation non-sedating H1 antihistamines in children with chronic spontaneous urticaria. Pediatr Allergy Immunol. Wiley Online Library. Published August 3, 2020. Accessed February 11, 2022. https://onlinelibrary.wiley.com/doi/10.1111/pai.13325 Schaefer P. Acute and Chronic Urticaria: Evaluation and Treatment. Am Fam Physician. Published June 2017. Accessed February 11, 2022. https://www.aafp.org/afp/2017/0601/p717.html Winters M. Clinical Practice Guideline: Initial Evaluation and Management of Patients Presenting with Acute Urticaria or Angioedema. AAEM - American Academy of Emergency Medicine. Published July 10, 2006. Accessed February 11, 2022. https://www.aaem.org/resources/statements/position/clinical-practice-guideline-initial-evaluation-and-management-of-patients-presenting-with-acute-urticaria-or-angioedema Foreign Bodies & Toxic Shock Syndrome Cone LA, Woodard DR, Byrd RG, Schulz K, Kopp SM, Schlievert PM. A recalcitrant, erythematous, desquamating disorder associated with toxin-producing staphylococci in patients with AIDS. J Infect Dis. NIH. PubMed.gov. Published April 1992. Accessed February 11, 2022. https://pubmed.ncbi.nlm.nih.gov/1552193/ Contou D, Colin G, Travert B, et al. Menstrual Toxic Shock Syndrome: A French Nationwide Multicenter Retrospective Study. Clin Infect Dis. Oxford Academic. Published January 15, 2022. Accessed February 11, 2022. https://academic.oup.com/cid/article-abstract/74/2/246/6255963 Parsonnet J, Hansmann MA, Delaney ML, et al. Prevalence of Toxic Shock Syndrome Toxin 1-Producing Staphylococcus aureus and the Presence of Antibodies to This Superantigen in Menstruating Women. J Clin Microbiol. NCBI. Published September 2005. Accessed February 11, 2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234102/ Shands KN, Schmid GP, Dan BB, et al. Toxic-Shock Syndrome in Menstruating Women: Association with Tampon Use and Staphylococcus aureus and Clinical Features in 52 cases. N Engl J Med. Published December 18, 1980. Accessed February 11, 2022. https://www.nejm.org/doi/full/10.1056/nejm198012183032502?casa_token=GVNPVVA8uB4AAAAA:LQTf1B8PlxwffYbLmuOeWnteCLdkKtwEydZDKn2lYW-NoNe8953D58cgSMnWVnwbN136BWtd23zr Streptococcal Toxic Shock Syndrome: All You Need to Know. Cdc.gov. Published November 23, 2021. Accessed February 11, 2022. https://www.cdc.gov/groupastrep/diseases-public/streptococcal-toxic-shock-syndrome.html Toxic Shock Syndrome (Other Than Streptococcal) (TSS) 2011 case definition. Cdc.gov. Reviewed April 16, 2021. Accessed February 11, 2022. https://ndc.services.cdc.gov/case-definitions/toxic-shock-syndrome-2011/ Foreign Bodies Continued - Management Coskun A, Erkan N, Yakan S, Yıldirim M, Cengiz F. Management of rectal foreign bodies. World J Emerg Surg. Published March 13, 2013. Accessed February 11, 2022. https://wjes.biomedcentral.com/articles/10.1186/1749-7922-8-11 O'Malley G, O'Malley R. Body Packing and Body Stuffing. Merck Manuals Professional Edition. Reviewed/Revised May 2020. Accessed February 11, 2022. https://www.merckmanuals.com/professional/special-subjects/recreational-drugs-and-intoxicants/body-packing-and-body-stuffing Guest Interview: Kenny Walks Across America Facebook. Facebook.com. Accessed February 11, 2022. https://www.facebook.com/KennywalksacrossAmerica Kenny Walks Across America. Kenny Walks Across America. Accessed February 11, 2022. http://www.kennywalksacrossamerica.com Recurring Sources Center for Medical Education. Ccme.org. http://ccme.org The Proceduralist. Theproceduralist.org. http://www.theproceduralist.org The Procedural Pause. Emergency Medicine News. Lww.com. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx The Skeptics Guide to Emergency Medicine. Thesgem.com. http://www.thesgem.com Trivia Question: Send answers to 2viewcast@gmail.com Be sure to keep tuning in for more great prizes and fun trivia questions! Once you hear the question, please email us your guesses at 2viewcast@gmail.com and tell us who you want to give a shout-out to. Be sure to listen in and see what we have to share!

Evidence Based Hair
Evidence Based Hair - Season 1, Episode 3 (Scarring Alopecia)

Evidence Based Hair

Play Episode Listen Later Feb 21, 2022 39:10


  STUDIES HIGHLIGHTED IN THIS EPISODE     FRONTAL FIBROSING ALOPECIA STUDIES   Maghfour J et al (starts at 3:09). The Association between Frontal Fibrosing Alopecia, Sunscreen, and Moisturizers: A Systematic Review with a Meta-Analysis. J Am Acad Dermatol. 2022 Jan 21 (online).   Sun et al (starts at 6:36). Characterization and Treatment of Prominent Facial Vasculature in the Setting of Frontal Fibrosing Alopecia J Am Acad Dermatol 2022 Jan 5; (online)   Lobato-Berezo et al (starts at 11:05). Frontal fibrosing alopecia in men: A multicenter study of 39 patients. J Am Acad Dermatol. 2022 Feb;86(2):481-484.   Bernardez C et al (starts at 13:57). Beard loss in men with frontal fibrosing alopecia. J Am Acad Dermatol. 2022 Jan;86(1):181-183.     LICHEN PLANOPILARIS STUDIES   Gardellini A et al (starts at 20:26). Lichen planopilaris-like eruption in chronic myeloid leukemia patient during treatment with nilotinib as second-line therapy. J Oncol Pharm Pract. 2022 Jan 17 (online)   Lahouel et al. Nilotinib-induced lichen planopilaris. Int J Dermatol. 2022 Jan;61(1):e37-e38.       CENTRAL CENTRIFUGAL CICATRICIAL ALOPECIA STUDIES   Jamerson et al (starts at 30:00). Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes Exp Dermatol. 2022 Jan 10       FOLLICULITIS DECALVANS STUDIES   Moussa A et al (starts at 34:58). Successful treatment of folliculitis decalvans with baricitinib: A case series. Australas J Dermatol. 2022 Jan 22.    

Evidence Based Hair
Evidence Based Hair - Season 1 Episode 1 (Feb 7 2022 - Androgenetic Alopecia and Alopecia Areata)

Evidence Based Hair

Play Episode Listen Later Feb 7, 2022 31:30


REFERENCED STUDIES FOR ANDROGENETIC ALOPECIA Silva et al (starts at 1:10). Randomized clinical trial of low-dose oral minoxidil for the treatment of female pattern hair Loss: 0.25 mg versus 1 mg. Journal of the American Academy of Dermatology;  Online Jan 2022. Therianou et al (starts at 3;18). How Safe Is Prescribing Oral Minoxidil in Patients Allergic to Topical Minoxidil? Journal of the American Academy of Dermatology. J Am Acad Dermatol Feb 2022. James JF et al. (starts at 4:51) Efficacy and safety profile of oral spironolactone use for androgenic alopecia: A systematic review. J Am Acad Dermatol. Feb 2022 Plante et al (starts at 8:05). The Need for Potassium Monitoring in Women on Spironolactone for Dermatologic Conditions. J Am Acad Dermatol. 2022 Jan 21 Online;S0190-9622(22)00081-0. Özcan D (starts at 10:59). Pediatric androgenetic alopecia: a retrospective review of clinical  characteristics, hormonal assays and   metabolic syndrome risk factors in 23 patients An Bras Dermatol. 2022 Jan 12; online Zong et al (starts at 14:40). Prevalence of ocular anomalies is increased in women with polycystic ovary syndrome-exploration of association with PAX6 genotype. Ophthalmic Genetics. 2022 Jan 11;1-4. Online Deng et al (starts at 15:51). Androgen receptor mediated paracrine signaling induces regression of blood vessels in the dermal papilla in androgenetic alopecia. J Invest Dermatol. Jan 2022 online Li K et al (starts at 18:48). Association of fibrosis in the bulge portion with hair follicle miniaturization in androgenetic alopecia. J Am Acad Dermatol 2022; Jan;86(1):213-215.   REFERENCED STUDIES FOR ALOPECIA AREATA Di Fillipo et al (starts at 22:14). Efficacy of 308-nm excimer therapy in alopecia areata: a retrospective study with long-term follow-up Photodermatol Photoimmunol Photomed 2022 Jan 21.  online. Ting H-C et al (starts at 25:30). Association between alopecia areata and retinal diseases: A nationwide population-based cohort study. J Am Acad Dermatol  2021 Nov 1; online Abdelkader HA et al (starts at 26:24). Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration. Australas J Dermatol. 2022 Jan 25. Online.

The Healthy Skin Show
230: {RESEARCH} Mindfulness Stress Reduction Benefits For Chronic Skin Problems Like Eczema + Psoriasis w/ Jessica Maloh

The Healthy Skin Show

Play Episode Listen Later Jan 27, 2022 31:58


Have you ever heard of MBSR (Mindfulness-Based Stress Reduction)? My guest today is going to tell us all about it, as well as research into why a mindfulness practice could be beneficial for those with chronic skin issues (such as eczema, psoriasis, and alopecia areata). Jessica completed her BSc at York University in Toronto, ON and has completed her Doctor of Naturopathy degree from the Canadian College of Naturopathic Medicine. Her passion for integrative medicine and research led her to a postdoc position at UC Davis' Department of Dermatology and now more recently, to work with Integrative Skin Science and Research. Her research interests include nutrition, the microbiome, mindfulness, and quality of life in various dermatological conditions. Join us as we discuss research surrounding the benefits of mindfulness for chronic skin rashes. Do you have a regular stress reduction and mindfulness practice? Let me know in the comments! In this episode: Can our state of mind affect our skin? What do the terms "itch intensity" and "itch catastrophizing" mean? Can a mindfulness practice help people with alopecia areata? What is MBSR (Mindfulness Based Stress Reduction)? Quotes “You can think of mindfulness as the practice of paying attention on purpose to the present moment without judgment.” [5:40] “Itch catastrophization could be thoughts along the lines of this itch is only going to continue to get worse and worse and it's never going to go away. And so seeing maybe the extremes of the negatives and the anticipation of it becoming gradually worse. And itch intensity is more so about the physical sensation of it really increasing and how you feel the itch.” [7:51] Links Follow Jessica on Instagram Articles highlighted in this episode: Alopecia - Gallo R, Chiorri C, Gasparini G, Signori A, Burroni A, Parodi A. Can mindfulness-based interventions improve the quality of life of patients with moderate/severe alopecia areata? A prospective pilot study. J Am Acad Dermatol. 2017;76(4):757-759. doi:10.1016/j.jaad.2016.10.012 Psoriasis - Kabat-Zinn J, Wheeler E, Light T, et al. Influence of a Mindfulness Meditation-Based Stress Reduction Intervention on Rates of Skin Clearing in Patients With Moderate to Severe Psoriasis Undergoing Photo Therapy (UVB) and Photochemotherapy (PUVA): Psychosom Med. 1998;60(5):625-632. doi:10.1097/00006842-199809000-00020 - Fordham B, Griffiths CEM, Bundy C. A pilot study examining mindfulness-based cognitive therapy in psoriasis. Psychology, Health & Medicine. 2015;20(1):121-127. doi:10.1080/13548506.2014.902483 Atopic Dermatitis - Lüßmann K, Montgomery K, Thompson A, et al. Mindfulness as Predictor of Itch Catastrophizing in Patients With Atopic Dermatitis: Results of a Cross-Sectional Questionnaire Study. Front Med. 2021;8:627611. doi:10.3389/fmed.2021.627611

Clippings: The Official Podcast of the Council for Nail Disorders
Episode 13 | Phenol matricectomy for onychocryptosis and longitudinal pain assessments in nail surgery

Clippings: The Official Podcast of the Council for Nail Disorders

Play Episode Listen Later Jan 4, 2022 11:20


Episode 13 features Dr. April Schachtel and Dr. Katherine Stiff reviewing the following recent publications:Vinay K, Narayan V, Thakur V, Choudhary R, Narang T, Dogra S, Varthya SB. “Efficacy and safety of phenol based partial matricectomy in treatment of onychocryptosis: A systematic review and meta-analysis.” J Eur Acad Dermatol Venereol. [Epub ahead of print].Ricardo JW, Qiu Y, Lipner SR. "“Longitudinal perioperative pain assessment in nail surgery.” J Am Acad Dermatol. [Epub ahead of print].

Clippings: The Official Podcast of the Council for Nail Disorders
Episode 12 | Dermoscopy of the Nail Unit and Dermoscopy of Pediatric Nail Unit Nevi

Clippings: The Official Podcast of the Council for Nail Disorders

Play Episode Listen Later Dec 10, 2021 13:08


Episode 12 features Dr. April Schachtel and Dr. Katherine Stiff reviewing the following recent publications:Iorizzo M, Starace M, Di Altobrando A, Alessandrini A, Veneziano L, Piraccini BM. “The value of dermoscopy of the nail plate free edge and hyponychium.” J Eur Acad Dermatol Venereol. 2021 Dec;35(12):2361-2366.Lee J, Park S, Lee D, Jang KT, Kwon EJ. "Longitudinal brush pigmentation on the hyponychium, a dermoscopic feature observed in pediatric nail matrix nevi.” J Am Acad Dermatol. 2021 Jun;84(6):1758-1760.

Clippings: The Official Podcast of the Council for Nail Disorders
Episode 11 | Melanocyte Distribution in the Nail Plate, Ultrasound Gel in Wart Cryotherapy and Forceps in Nail Surgery

Clippings: The Official Podcast of the Council for Nail Disorders

Play Episode Listen Later Nov 3, 2021 13:27


Episode 11 features Dr. April Schachtel and Dr. Katherine Stiff reviewing the following recent publications:Oh SJ, Lee J, Lee JH, Bae J, Park JH, Lee JH, Lee D. Distribution of cellular remnants of melanocytes in the nail plate: Clue to the diagnosis of subungual melanoma. Journal of Cutaneous Pathology.2021[Epub ahead of print].Vedamurthy M, Raghupathy S, Vanasekar P. Use of ultrasound gel to increase efficacy of cryotherapy in treatment of warts. J Am Acad Dermatol. 2021 [Epub ahead of print].Cai W, Wu C, Peng J, Chen M. “Application of Forceps in The Operation of Nail or Toenail. J Am Acad Dermatol. 2021 [Epub ahead of print].

Learn Derm Podcast
Ep38 – MISC – Bumps in a Baby

Learn Derm Podcast

Play Episode Listen Later Sep 1, 2021 25:57


Bumps in a baby?! Say it ain't so! In this episode, we discuss the differential diagnosis for bumps in infants and young children ranging from benign lesions, such as milia, to more serious lesions, such as pediatric melanomas. References: Bouraoui S, Mlika M, Kort R, Cherif F, Lahmar A, Sabeh M. Miliary osteoma cutis of the face. J Dermatol Case Rep. 2011;5(4):77-81. doi:10.3315/jdcr.2011.1082 Gupta D, Frieden I, Cordoro K, Kashani-Sabet, M. and McCalmont, T. Evidence for modification of the ABCDE criteria for pediatric melanoma. J Am Acad Dermatol, 2012;66(4). doi.org/10.1016/j.jaad.2011.11.011 Paller AS, Mancini AJ. Hurwitz Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence. Edinburgh: Elsevier; 2016. Connect with us: Facebook │ Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review. When he's up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours? Musical support provided by: • Daniel Thompson(bass) • Alec Tackmann (drums) • Thomas and the Shakes Terms of use: The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates. By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Learn Derm Podcast
Ep37 – MISC – Hyperhidrosis

Learn Derm Podcast

Play Episode Listen Later Aug 18, 2021 29:19


In this episode, we touch on another common presentation to dermatology offices – hyperhidrosis. Sweaty palms, sweaty pits, sweaty anything can be very frustrating for patients and very rewarding to get adequate treatment. We'll discuss pearls in the diagnosis, differential, and treatment toolkit! References: Nawrocki S, Cha J. The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Etiology and clinical work-up. J Am Acad Dermatol. 2019;81(3):657-666. doi:10.1016/j.jaad.2018.12.071 Nawrocki S, Cha J. The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Therapeutic options. J Am Acad Dermatol. 2019;81(3):669-680. doi:10.1016/j.jaad.2018.11.066 Hu Y, Converse C, Lyons MC, Hsu WH. Neural control of sweat secretion: a review. Br J Dermatol. 2018;178(6):1246-1256. doi:10.1111/bjd.15808 Connect with us: Facebook │ Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review. When he's up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours? Musical support provided by: • Daniel Thompson(bass) • Alec Tackmann (drums) • Thomas and the Shakes Terms of use: The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates. By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Learn Derm Podcast
Ep35 – MISC – HS Part II – Pathogenesis, Comorbidities, & Treatment

Learn Derm Podcast

Play Episode Listen Later Jul 14, 2021 29:16


In the second episode of season 3, we continue our three episode series on hidradenitis suppurativa with a discussion of the pathogenesis, comorbidities, and treatment of HS. We break down the complex treatment of HS into five categories including trigger avoidance, topical therapies, systemic oral agents, biologics, and surgery. References: Alikhan A, Sayed C, Alavi A, et al. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. J Am Acad Dermatol. 2019;81(1):76-90. doi:10.1016/j.jaad.2019.02.067 Alikhan A, Sayed C, Alavi A, et al. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. J Am Acad Dermatol. 2019;81(1):91-101. doi:10.1016/j.jaad.2019.02.068 Connect with us: Facebook │ Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review. When he's up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours? Musical support provided by: • Daniel Thompson(bass) • Alec Tackmann (drums) • Thomas and the Shakes Terms of use: The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates. By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Clippings: The Official Podcast of the Council for Nail Disorders
Episode 7 | Nail Psoriasis as Coronary Risk Factor and Terbinafine 10% Solution for Onychomycosis

Clippings: The Official Podcast of the Council for Nail Disorders

Play Episode Listen Later Jul 8, 2021 13:04


Episode 7 features Dr. April Schachtel and Dr. Katherine Stiff reviewing the following recent publications:Colunga-Pedraza IJ et al. Nail involvement in psoriatic arthritis patients is an independent risk factor for carotid plaque. Annals of the Rheumatic Diseases Published Online First: 24 June 2021.Gupta AK et al. Terbinafine 10% solution (MOB-015) in the treatment of mild to moderate distal subungual onychomycosis: A randomized, multicenter, double-blind, vehicle-controlled phase 3 study. J Am Acad Dermatol. 2021;85(1):95-104.

Emergency Medical Minute
Podcast 670: Operation Tat-Type

Emergency Medical Minute

Play Episode Listen Later May 12, 2021 4:30


Contributor:  Dave Rosenberg, MD Educational Pearls: In 1951, Operation Tat-Type began tattooing adults with their blood type in an effort to prepare for rapid transfusions in the time of the Cold War and the Korean War School children in northern Indiana and areas in Utah were tattooed with their blood type beginning in 1952 under the same operation Based on tattoos given to SS officers during WWII This wasn't to identify who needed what blood but rather to identify who could give what blood in the event of a massive attack References Wolf EK, Laumann AE. The use of blood-type tattoos during the Cold War. J Am Acad Dermatol. 2008;58(3):472-476. doi:10.1016/j.jaad.2007.11.019 Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD   The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at www.emergencymedicalminute.com/cme-courses/ and create an account.  Donate to EMM today!

Clippings: The Official Podcast of the Council for Nail Disorders
Episode 2 | Lichen Planus Expert Treatment Guidelines and Onychomycosis Quality of Life

Clippings: The Official Podcast of the Council for Nail Disorders

Play Episode Listen Later Feb 12, 2021 21:31


Episode 2 features Dr. April Schachtel and Dr. Katherine Stiff reviewing the following recent publications:Iorizzo et al. Isolated nail lichen planus: An expert consensus on treatment of the classical form. J Am Acad Dermatol 2020 Dec;83(6):1717-1723.Stewart et al. Effect of onychomycosis and treatment on patient-reported quality-of-life outcomes: A systematic review. J Am Acad Dermatol 2020 [Online Head of Print]

Clippings: The Official Podcast of the Council for Nail Disorders
Episode 1 | Apremilast and Intralesional Methotrexate for Nail Psoriasis

Clippings: The Official Podcast of the Council for Nail Disorders

Play Episode Listen Later Dec 23, 2020 15:44


Episode 1 features Dr. April Schachtel and Dr. Katherine Stiff reviewing the following recent publications:Allen Oak, Hoang Ho-Pham, Boni Elewski. Improvement of 11 patients with nail psoriasis with apremilast: Results of an investigator-initiated open-label study. J Am Acad Dermatol. 2020 Dec;83(6):1830-1832.Paras Choudhary, Rajesh Datt Mehta, Bhikam Chand Ghiya, Divya Sharma. Treatment of nail psoriasis with intramatrical methotrexate: An uncontrolled prospective study of 20 patients. J Am Acad Dermatol. 2020 [Epub ahead of print].

Morgellons Discussion
Why using Morgellons as a "rapport enhancing term" for DOP patients is a Baaaaaaad idea

Morgellons Discussion

Play Episode Listen Later Sep 29, 2020 8:56


Pulmonary fibrosis https://www.mayoclinic.org/diseases-conditions/pulmonary-fibrosis/symptoms-causes/syc-20353690 USC researchers think THC in marijuana may be able to treat deadly COVID complication https://www.thestate.com/news/coronavirus/article245321785.html American's for Safe Access https://www.safeaccessnow.org/ History of Morgellons disease: from delusion to definition https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811176/ Middelveen MJ, Fesler MC, Stricker RB. History of Morgellons disease: from delusion to definition. Clin Cosmet Investig Dermatol. 2018;11:71-90. Published 2018 Feb 9. doi:10.2147/CCID.S152343 Morgellons disease: A rapport-enhancing term for delusions of parasitosis https://pubmed.ncbi.nlm.nih.gov/17052509/ Murase JE, Wu JJ, Koo J. Morgellons disease: a rapport-enhancing term for delusions of parasitosis. J Am Acad Dermatol. 2006 Nov;55(5):913-4. doi: 10.1016/j.jaad.2006.04.042. PMID: 17052509. --- Send in a voice message: https://anchor.fm/morgellons/message Support this podcast: https://anchor.fm/morgellons/support