Podcasts about dermis

Preaching for the Feast of Our Lady of Guadalupe, Dermis de Jesús offers a reflection on Our Lady's message of accompaniment: "Our Lady of Guadalupe recognized the dignity of the people of México, the color of their skin, their language, chose them as messengers. Her message of accompaniment- “Am I not here; I who am your mother?”- resonates with us today as it resonated with St. Juan Diego, and propels us to be courageous in how we respond to God's calling, in how we spread God's word and God's love." Dermis de Jesús worships and serves at St. Vincent de Paul Parish in Philadelphia. She is active in various ministries, including lay leader of prayer, coordinating and directing the children's choir, co-coordinating the Spanish language Mass, Eucharistic Minister and lector. She is a past recipient of the St. Vincent de Paul Award, nominated for exemplifying Vincentian values. A native of Puerto Rico, Dermis calls Philadelphia her second home, where she lives with her husband, Willhem, their children Sofía and Marcos, and their dog, Mario. Visit www.catholicwomenpreach.org/preaching/12122024 to learn more about Dermis, to read her preaching text, and for more preaching from Catholic women.

¿Cómo es la piel de nuestras mascotas y qué funciones tiene? La piel del perro y el gato es una membrana flexible que cubre todo su cuerpo, representando entre el 12 y el 24% de su peso total, lo que la convierte en su órgano más extenso. Funciona como una barrera protectora contra diversos patógenos. Este escudo natural tiene un grosor que varía entre uno y cinco milímetros, según la zona del cuerpo, y apenas contiene glándulas sudoríparas. Es el principal receptor de estímulos como frío, calor, contacto, dolor o picazón.Sin embargo, la piel de los perros y los gatos guardan muchas similitudes. Ambas se componen de tres capas: Epidermis, que es la capa externa y está en contacto directo con el exterior. Dermis, situada bajo la epidermis, más gruesa y que contiene vasos sanguíneos, linfáticos, nervios, glándulas sebáceas y sudoríparas, además de folículos pilosos. Hipodermis, la capa más profunda. Compuesta principalmente de tejido graso.Eso sí, si hay un aspecto que ...

Are you a med spa or aesthetic clinic trying to retain more customers? Dermis.ai's new mobile rewards app is your perfect solution! Visit https://www.dermis.ai for more. Dermis Software Labs City: Wilmington Address: 1007 Orange Street Website: https://dermis.ai Phone: +1 917-810-2173 Email: valentin@dermis.ai

This episode features selections from The Dermis Probe by Idries Shah.

Síndrome de la piel permeable. Para hablar de ello nos acompañó Dr. Juan Carlos Méndez, Especialista en Medicina Antienvejecimiento La piel es el órgano más extenso del cuerpo con unos 2 metros cuadrados de superficie y unos 5 kg de peso., compuesta por 3 capas Epidermis: capa superficial que tiene la función de impermeabilizar, proteger e interactuar con el medio ambiente. Dermis: capa medio que tiene la función de unir, nutrir e hidratar la piel. Hipodermis o tejido celular subcutáneo., capa profunda con la función de amortiguar, termoregular y regenerar la piel. En la dermatitis atópica falla fundamentalmente la función de barrera. la piel se torna permeable debido a una alteración de las proteínas de adhesión celular (desmosimas), trayendo como consecuencias: Al abrirse las cremalleras que mantienen la barrera intacta, se habilita a la entrada de diversas toxinas (ambientales, de cremas químicas, de pinturas de juegos, de ácaros, etc). La entrada de bacterias patógenas que generan enfermedades como el impétigo; y de virus como los moluscos contagiosos o las verrugas por VPH. Permite la salida de agua corporal, generando una piel seca, descamativa y pruriginosa. Todos estos factores participan en que la piel curse un estado de inflamación crónica que actúa como perpetuarte de la enfermedad.”

This episode features selections from The Dermis Probe by Idries Shah.

Thanks to Cecilio for sending in this question. James Tytko asked University of Leeds Professor of Dermatology, Julia Newton Bishop, for assistance... Like this podcast? Please help us by supporting the Naked Scientists

Imagine a suit that fits you perfectly, doesn't wrinkle for years, repairs itself, is waterproof, has air conditioning and heating, and protects you against damage and radiation. And it's all for free. You're wearing it now. This is your skin. The human body is a beautiful and mysterious machine. We collect the most interesting facts about the human body, and today, we're going to figure out how the human skin works. So, your skin consists of three layers: the Epidermis, Dermis, and Hypodermis. The epidermis is the uppermost layer of your skin. This is your personal waterproof armor that protects the body from bacteria and damage. The lifespan of this armor isn't long, but the old cells are completely replaced with new ones after 4-6 weeks. By the way, half of the dust found in your house is old skin cells! Yuck!... But let's go deeper and find out what your skin is made of, why it's so sensitive, why the skin on your scars looks a little different, and some other interesting facts about the human body's largest organ. Learn more about your ad choices. Visit megaphone.fm/adchoices

Frankie B is controversial on TCB. Love him, hate him he's a part of the show. And when Frank is on a roll, we should sit back and enjoy. Frankie B is back with a video on how to "Be Best" over 50. Let's get in on the action while it's around, shall we? Christmas Vacation is a bad movie? Of course not! Which Vacation movie is the best? Krissy is wearing tape bikinis! Maneskin is a great rock band. But the boobs are taking over the talent Frankie in the Meta-verse? Doubt it Frankie is back with a video on how to Be Best! Frankie tells us to go deep in dermis and not the dingus LINKS: Send us show ideas, comments, questions or concerns by texting us or leaving a voicemail at 1-661-Best-2-Yo (1.661.237.8296) Watch Us on YouTube American Musical Supply is offering $20 off any purchase over $100 Take a Listen to The Jordan Harbinger show! Dumb People Town Is a Very Funny Podcast From Starburns Audio Use This Link For Unlimited Talk & Tex on MINT MOBILE! Special Thanks To Our Associate Content Producers: Tina Rose Big Will The Champ Marianne Duke Luke Gustavo New Episodes on Monday, Wednesday and now Fridays everywhere you listen to podcasts! 1-(661)-BEST-2-YO  | (1-661-237-8296) This episode is sponsored by American Musical Supply. Go Here and use promo code TCB to receive $20 off a purchase over $100. Learn more about your ad choices. Visit megaphone.fm/adchoices

In today's episode, someone forgets their wedding anniversary, a cheese chalet shames Wisconsin, and a scalp tickler ruins my life. If you like the show, PLEASE TELL A FRIEND? That's our advertising for the moment.  Buy our shirts and cups: https://www.designbyhumans.com/shop/CriticEveryone/ Yell at us: foreveracritic@gmail.com Tweet at us: @CriticEveryone Allow conspiracies to fester with us: Facebook Fan Page: https://www.facebook.com/Everyones-a-Critic-2327696304154655/ Listen to the other great shows on our network: https://xraypod.com/ I did really hug Tommy Wiseau once. 

Episode 464 -- The A's are one defeat away from 100 losses after Wednesday night, but Dermis Garcia and Kirby Snead each showed something that could be building blocks for 2023. Then, let's try and get optimistic about a 100 loss season by looking back at A's history. Finally, Aaron Judge tied Roger Maris' AL home run mark and Jason has some takes. Get social with us: @ByJasonB + @LockedonAs Subscribe to our YouTube channel! Support Us By Supporting Our Sponsors! Built Bar Built Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order. BetOnline BetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts! LinkedIn LinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB. BlueChew Try BlueChew FREE when you use our promo code LOCKEDON at BlueChew.com,-just pay $5 shipping.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode 464 -- The A's are one defeat away from 100 losses after Wednesday night, but Dermis Garcia and Kirby Snead each showed something that could be building blocks for 2023.Then, let's try and get optimistic about a 100 loss season by looking back at A's history.Finally, Aaron Judge tied Roger Maris' AL home run mark and Jason has some takes.Get social with us: @ByJasonB + @LockedonAsSubscribe to our YouTube channel!Support Us By Supporting Our Sponsors!Built BarBuilt Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order.BetOnlineBetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts!LinkedInLinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB.BlueChewTry BlueChew FREE when you use our promo code LOCKEDON at BlueChew.com,-just pay $5 shipping.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode 457 -- After wondering aloud how Dermis Garcia compares to early-career Khris Davis, Jason compares their stat lines to see if the A's have their unexpected slugger for this rebuild. Then, prospects are on the move to Las Vegas to finish out the season, so let's talk about Tyler Soderstrom, Zack Gelof, Kyle McCann, and Jeff Criswell. Get social with us: @ByJasonB + @LockedonAs Subscribe to our YouTube channel! Support Us By Supporting Our Sponsors! Nugenix Now get a complimentary bottle of Nugenix Total T when you text MLB to 231-231. Text now and get a bottle of Nugenix Thermo, their most powerful fat incinerator ever, with key ingredients to help you get back into shape fast. Built Bar Built Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order. BetOnline BetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts! LinkedIn LinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB. BlueChew Try BlueChew FREE when you use our promo code LOCKEDON at BlueChew.com,-just pay $5 shipping.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode 457 -- After wondering aloud how Dermis Garcia compares to early-career Khris Davis, Jason compares their stat lines to see if the A's have their unexpected slugger for this rebuild.Then, prospects are on the move to Las Vegas to finish out the season, so let's talk about Tyler Soderstrom, Zack Gelof, Kyle McCann, and Jeff Criswell.Get social with us: @ByJasonB + @LockedonAsSubscribe to our YouTube channel!Support Us By Supporting Our Sponsors!NugenixNow get a complimentary bottle of Nugenix Total T when you text MLB to 231-231. Text now and get a bottle of Nugenix Thermo, their most powerful fat incinerator ever, with key ingredients to help you get back into shape fast.Built BarBuilt Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order.BetOnlineBetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts!LinkedInLinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB.BlueChewTry BlueChew FREE when you use our promo code LOCKEDON at BlueChew.com,-just pay $5 shipping.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode 453 -- The Oakland A's split their series in Texas with the Rangers, and Dermis Garcia went deep in both games, giving him four home runs and 13 rbi in the season. He's certainly making the case to be the A's first baseman to begin the 2023 season. Then, looking in on Ken Waldichuk and JP Sears after their Texas starts. Finally, Jason goes over the Houston Astros series this weekend, and predicts which games are winnable. Get social with us: @ByJasonB + @LockedonAs Subscribe to our YouTube channel! Support Us By Supporting Our Sponsors! Built Bar Built Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order. BetOnline BetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts! LinkedIn LinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB. BlueChew Try BlueChew FREE when you use our promo code LOCKEDON at BlueChew.com,-just pay $5 shipping.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode 453 -- The Oakland A's split their series in Texas with the Rangers, and Dermis Garcia went deep in both games, giving him four home runs and 13 rbi in the season. He's certainly making the case to be the A's first baseman to begin the 2023 season.Then, looking in on Ken Waldichuk and JP Sears after their Texas starts.Finally, Jason goes over the Houston Astros series this weekend, and predicts which games are winnable.Get social with us: @ByJasonB + @LockedonAsSubscribe to our YouTube channel!Support Us By Supporting Our Sponsors!Built BarBuilt Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order.BetOnlineBetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts!LinkedInLinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB.BlueChewTry BlueChew FREE when you use our promo code LOCKEDON at BlueChew.com,-just pay $5 shipping.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode 446 -- Dermis Garcia hit his first big league home run on Tuesday, and followed that up with a mammoth 467 foot bomb on Wednesday. Have the A's found their first baseman for 2023? Then, with Dany Jimenez and Zach Jackson out, who should be closing games for the Oakland A's? Finally, we get you ready for Ken Waldichuk's big league debut on Thursday at Nationals Park. Waldichuk was acquired from the New York Yankees as the centerpiece of the Frankie Montas trade at the end of July. Get social with us: @ByJasonB + @LockedonAs Subscribe to our YouTube channel! Support Us By Supporting Our Sponsors! Built Bar Built Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order. BetOnline BetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts! LinkedIn LinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode 446 -- Dermis Garcia hit his first big league home run on Tuesday, and followed that up with a mammoth 467 foot bomb on Wednesday. Have the A's found their first baseman for 2023?Then, with Dany Jimenez and Zach Jackson out, who should be closing games for the Oakland A's?Finally, we get you ready for Ken Waldichuk's big league debut on Thursday at Nationals Park. Waldichuk was acquired from the New York Yankees as the centerpiece of the Frankie Montas trade at the end of July.Get social with us: @ByJasonB + @LockedonAsSubscribe to our YouTube channel!Support Us By Supporting Our Sponsors!Built BarBuilt Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order.BetOnlineBetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts!LinkedInLinkedIn Jobs helps you find the candidates you want to talk to, faster. Did you know every week, nearly 40 million job seekers visit LinkedIn? Post your job for free at LinkedIn.com/LOCKEDONMLB. Learn more about your ad choices. Visit podcastchoices.com/adchoices

En nuestro episodio de hoy de la sección el cuerpo habla lo que la boca calla, vamos a darles la información sobre la piel y la epidermis, con este padecimiento llamado Neurofibroma. . . #taniaramón #spotify #centroquantum #podcast #googlepodcasts #quantum #spotifypodcast #applepodcasts #taniaramón

Our skin is an incredibly important, multifunctional organ. It has many different functions including helping us maintain our body temperature, it assists with the excretion of water and toxins, and most importantly, protective mechanism of acting as a barrier. But in newborns, especially preterm infants, there are developmental differences in the anatomy and physiology of their skin that place them at an increased risk for skin injury. Not only is the immaturity of an infant's skin problematic, but infants in the NICU are predisposed to skin trauma due to the life-saving monitors and equipment necessary for their care. Furthermore, infants with compromised skin integrity are at an increased risk for infection, excess water loss, absorption of toxic substances, and additional sequelae. On this episode, we review the basic anatomy of our skin and all of its important functions. We discuss how the skin of a term and preterm infants differs from adults and why the structural variations place infants at an increased risk for skin trauma and additional complications. The episode will be beneficial for parents of infants, especially preterm infants or those in the NICU to understand why their infant is at an increased risk for compromised skin integrity. NICU clinicians will also hear a great reminder of the anatomical and physiologic variations in infants that place them at an increased risk for skin injury. Our NICU Roadmap: A Comprehensive NICU Journal: https://empoweringnicuparents.com/nicujournal/NeoTech Free Samples: neotechneoshades.comNICU Mama Hats: https://empoweringnicuparents.com/hats/NICU Milestone Cards: https://empoweringnicuparents.com/nicuproducts/Empowering NICU Parents Show Notes: https://empoweringnicuparents.com/episode34Empowering NICU Parents Instagram: https://www.instagram.com/empoweringnicuparents/Empowering NICU Parents FB Group: https://www.facebook.com/groups/empoweringnicuparentsPinterest Page: https://pin.it/36MJjmH

Welcome to the Velocity Chaos Podcast! This is the 66th Episode of the Velocity Chaos Podcast!!  Luke, Nick, and DJ Runner Up talk about the Dark Web, Donkeys, and the Dermis! They get into a Segment on How Tattoos Do That, Do Some Master Debating on Painting, Talk about the Conspiracy Theories of the Internet, and Pitch a Movie Based on a True Story about a 2000 Year Old Sculpture. All that and more on this episode of Velocity Chaos Podcast! Thank you all so much!   Be sure to Like, Comment, Subscribe, and or leave a rating on all the platforms! Share it with your friends! Instagram Facebook YouTube www.VelocityChaos.Libsyn.com  Spotify Apple Podcast iheartRadio Episode Links Segment 1 How Does it Do That? - Tattoos https://www.drdoppelt.com/tattoos-whats-happening-under-your-skin/#:~:text=The%20ink%20is%20injected%20into,permanent%20designs%2C%20images%20and%20masterpieces https://www.youtube.com/watch?v=QkVTFiyW5dg  https://authoritytattoo.com/what-is-tattoo-ink-made-of/  Segment 2 Master Debaters - Painting Segment 3 Conspiracy Theory - 8 Levels of the internet https://medium.com/nerd-for-tech/mysterious-side-of-the-internet-5d2a02e103b7  Segment 4 Based on a True Story - 2000 Year Old Statue https://www.npr.org/2022/05/07/1097376953/she-found-a-2-000-year-old-sculpture-at-goodwill-it-took-years-to-get-rid-of-it  Aussie News Brain Visitation https://www.abc.net.au/news/2022-06-26/u-t-place-philosophy-of-brains-and-minds-university-of-adelaide/101158816  Recommendation Dr Squatch Soap https://drsquatch.com/  Songs are free YouTube songs:  Jason Farnham - World Map E's Jammy Jams - Soul and Mind Didgeridoo Royalty Free Music Infraction - Upbeat Funk Rock [No Copyright Music] _ Saturday  Send us an email about anything If you have any questions or topics you would like us to get into, please email VelocityChaosPodcast@gmail.com  We'll see if we can tackle your question in an upcoming episode! Timecodes are slightly off, because they are taken from the YouTube Video Timeline. 0:00 Intro 0:20 Welcome and Show Set up 2:42 Missed Connection - Vikings and Luaus 4:42 Segment 1 - How Does it Do That? - Tattoos 20:21 Ad Break 1 - Gas Away 31:37 Segment 2 - Master Debaters - Painting with Head or Knees? 29:56 Segment 3 - Conspiracy Theory - Levels of the Internet 55:08 Ad Break 2 - Light 56:15 Segment 4 - BoaTS - 2000 Year Old Sculpture 1:17:03 Australian News - Brain Visitation 1:20:25 Summation 1:22:05 Recommendation - Dr Squatch Soaps 1:23:54 Outro

Frankie's guests include the President and CEO of Women's World Banking and author of new book 'There's Nothing Micro About a Billion Women: Making Finance Work For Women' Mary Ellen Iskenderian AND insightful registered pharmacist Ben Fuchs to discuss his own line of skin care and to discuss current events like the baby formula shortage.Mary Ellen Iskenderianhttps://www.meiskenderian.com/Mary Ellen Iskenderian (@MEIskenderian) / Twitterhttps://www.womensworldbanking.org/about-us/our-team/mary-ellen-iskenderian/BOOK: There's Nothing Micro About a Billion Women: Making Finance Work For Women (MIT Press; April 19, 2022)Mary Ellen Iskenderian, author of There's Nothing Micro About a Billion Women: Making Finance Work For Women, is President and CEO of Women's World Banking, a global nonprofit devoted to giving more low-income women access to financial tools and resources they need for both security and prosperity. Mary Ellen is a permanent member of the Council on Foreign Relations, as well as a member of the Women's Forum of New York, and the UN's Business and Sustainable Development Commission. https://www.womensworldbanking.org/Ben Knight Fuchs is a regenerated pharmacist, whose mission is the natural approach. No drugs. Ben is a pioneer in natural skin care as well with a successful business. For the past 35 years he has been developing pharmacy-potent skin health products for estheticians, dermatologists, plastic surgeons and his own savvy customers. https://www.truthtreatments.com/Ben FuchsRegistered pharmacisthttps://www.truthtreatments.com/******Frankie Boyer is an award winning talk show host that empowers listeners to live healthy vibrant lives http://www.frankieboyer.com

Salimos por un rato del indie puro y nos vamos a lo alternativo que significa el rock clásico en el indie. Un poco hard, un poco canción, siempre potentes, tres propuestas locales y actuales que trae Neptu. - Mica Racciatti: Tiempo / Mil Imperios (2022) - Trilema: Rostros (De Otro Lugar) / Deslizando Rumbos, vol 1(2021) - Cepillo: Cuando la noche llega / Dermis (2017) El Radar de Neptuno suena en Falso Vivo todos los martes y en Escena UNR todos los jueves. Seguí las playlists de la Escena Musical Rosarina acá: https://open.spotify.com/user/nchbnrdvl4hycn6vp93ws2248?si=25a61e8c73454923

Namaste, Welcome to SAM-VAD (Together In Conversation), as we begin today ‘let us remember this about ‘Attention'. Our life experience would ultimately amount to whatever we had paid attention to. […]

The guys are talking about how Josh dressed like an old man, bullies, and how The Eternals shouldn’t have genitalia. Watch the video at https://youtu.be/U34Or2YAgNA WHAT ARE THEY PLAYING WITH? Bob: LEGO Batman TV Series Cowl Set #76238 Josh: LEGO Bonsai Tree Set #10281 Find out More from Bob and Josh: Home Youtube: http://youtube.com/iliketomakestuff http://youtube.com/josh_makesstuff Instagram: http://instagram.com/iliketomakestuff http://instagram.com/josh_makesstuff Twitter: Tweets by iliketomakestuf Tweets by josh_makesstuff

The guys are talking about how Josh dressed like an old man, bullies, and how The Eternals shouldn’t have genitalia. Watch the video at https://youtu.be/U34Or2YAgNA WHAT ARE THEY PLAYING WITH? Bob: LEGO Batman TV Series Cowl Set #76238 Josh: LEGO Bonsai Tree Set #10281 Find out More from Bob and Josh: Home Youtube: http://youtube.com/iliketomakestuff http://youtube.com/josh_makesstuff Instagram: http://instagram.com/iliketomakestuff http://instagram.com/josh_makesstuff Twitter: Tweets by iliketomakestuf Tweets by josh_makesstuff

The guys are talking about how Josh dressed like an old man, bullies, and how The Eternals shouldn’t have genitalia. Watch the video at https://youtu.be/U34Or2YAgNA WHAT ARE THEY PLAYING WITH? Bob: LEGO Batman TV Series Cowl Set #76238 Josh: LEGO Bonsai Tree Set #10281 Find out More from Bob and Josh: Home Youtube: http://youtube.com/iliketomakestuff http://youtube.com/josh_makesstuff Instagram: http://instagram.com/iliketomakestuff http://instagram.com/josh_makesstuff Twitter: Tweets by iliketomakestuf Tweets by josh_makesstuff

A post-trip bonanza with reviews and observations from our latest Strip stay, including Superfrico, Lady Gaga and much more The post FHBM #806: Immerse Your Dermis first appeared on Five Hundy By Midnight.

Most tattoos tell a sentimental story. This episode tells the story of what happens in our body when we get a tattoo. Alex Machado, a tattoo artist who has been in the industry and tattooing for 28 years, describes the anatomy of a tattoo. He explains where the ink goes in the skin, how the body accepts the ink, and how and why a tattoo really is permanent. Alex also details how different it is to tattoo various skins, such as wrinkly or thick skin. While the audio quality isn't what you are used to hearing from The Anatomy Nerd Podcast, I encourage you to be patient and tune in to this fascinating and fun episode. Alex has a lot to share, and we tried our very best to get clear audio. Buzzsprout - Let's get your podcast launched! Start for FREEDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the show (https://www.patreon.com/theanatomynerdpodcast)

Das Erysipel, umgangssprachlich auch als Wundrose bezeichnet, ist eine bakterielle Infektion und Entzündung der oberen Hautschichten und Lymphwege, die sich durch eine scharf begrenzte Rötung mit zungenförmigen Ausläufern und gelegentlich einer epidermalen Beteiligung auszeichnet. Diese Hautentzündungen treten typischerweise an den Unterschenkeln und Füßen, selten jedoch auch im Gesicht auf. Das Erysipel ist eine durch Streptokokken der Gruppe A verursachte Infektion der Lymphgefäße in der Dermis. Die Symptome einer Wundrose sind durch eine Schwellung der Lymphknoten, ausgeprägtes Krankheitsgefühl, Druckschmerz, Fieber und Kopfschmerzen gekennzeichnet.

Learn about how disgusting sights literally turn your stomach; and why tattoos are permanent. Then, play along at home as we test your podcast knowledge in this month’s edition of the Curiosity Challenge trivia game. Disgusting sights literally turn your stomach by Cameron Duke Nord, C. L., Dalmaijer, E. S., Armstrong, T., Baker, K., & Dalgleish, T. (2020). A Causal Role for Gastric Rhythm in Human Disgust Avoidance. Current Biology. https://doi.org/10.1016/j.cub.2020.10.087  Rhythm and bleughs: changes in our stomach’s rhythms steer us away from disgusting sights. (2020). EurekAlert! https://www.eurekalert.org/pub_releases/2020-11/uoc-rab112320.php  Why are tattoos permanent? by Cameron Duke Baranska, A., Shawket, A., Jouve, M., Baratin, M., Malosse, C., Voluzan, O., Vu Manh, T.-P., Fiore, F., Bajénoff, M., Benaroch, P., Dalod, M., Malissen, M., Henri, S., & Malissen, B. (2018). Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal. Journal of Experimental Medicine, 215(4), 1115–1133. https://doi.org/10.1084/jem.20171608  How wounds heal: MedlinePlus Medical Encyclopedia. (2017). Medlineplus.gov. https://medlineplus.gov/ency/patientinstructions/000741.htm  Specktor, B. (2018, March 6). Tattoos Last Forever Because Your Immune Cells Are Hungry for Dead Skin. Livescience.com; Live Science. https://www.livescience.com/61932-why-tattoos-last.html  Episodes referenced in the Curiosity Challenge trivia game: Battery-powered airplanes: https://www.curiositydaily.com/why-dont-we-have-battery-powered-airplanes/  Smacking electronics: https://www.curiositydaily.com/why-its-relaxing-to-breathe-in-through-your-nose/  Cream in coffee: https://www.curiositydaily.com/why-you-need-self-compassion-for-self-improvement/  Subscribe to Curiosity Daily to learn something new every day with Cody Gough and Ashley Hamer. You can also listen to our podcast as part of your Alexa Flash Briefing; Amazon smart speakers users, click/tap “enable” here: https://www.amazon.com/Curiosity-com-Curiosity-Daily-from/dp/B07CP17DJY See omnystudio.com/listener for privacy information.

¡Bienvenida a la serie Conociendo tu Tu Tipo de Piel! Este episodio da comienzo a la serie de Conociendo Tu Tipo de piel, pero antes de comenzar hablar de cada tipo de piel, debes saber un poco de cómo Tu piel funciona como está compuesta tu piel. Habló sobre la Epidermis y la Dermis. Espero que te pueda ayudar durante esta serie a que identifiques tu tipo de piel. Espero que les guste recuerda que puedes ver la notas en mi blog de www.cuidatupielhoy.com  

Todas queremos tener una piel sana, pero ¿sabemos tratar la nuestra? Lo primero de todo es saber qué tipo de piel tenemos y después usar productos específicos para un buen cuidado. La dermatóloga Irela Reig Macías, de TopDoctors, nos explica cómo averiguar cuál es nuestro tipo de piel y qué rutinas requiere para mantenerla sana, libre de manchas y cicatrices. ¡Dale al play!

Venezuela no siempre ha sido noticia por la política; también lo fue en los noventas por la música y específicamente por el rock. En 1995 la banda Dermis Tatú lanzaría el que es considerado el mejor disco de rock de un grupo venezolano, titulado "La Violó, La Mató, La Picó", grabado en Buenos Aires, Argentina, y hoy dedicamos nuestra nueva emisión, presentada por Ricardo Portmán, a este power trío liderado por el recordado Cayayo Troconis. Si eres venezolano disfrutarás a rabiar con este programa y si eres de otro país puede ser un muy interesante descubrimiento. Se podrán escuchar: Dirección Opuesta (tema inédito) El Chillido de los Taxis Zorra El Hoyo Sordera  Error por Cometer Asco Corazón Gris Ausencia Terrenal H (+ Bonus track -temas inéditos Despistado, Animalito en Corral y Cría Cuervos)

We're sitting down with the gorgeous and talented Ally Dawson! She is friend, and Skin GURU! Who is currently finessing her skin skills at GLOW BAR in lower Manhattan here in NYC where she is a licensed esthetician. Ally is my go to gal for all things skin! In our most informative episode to date, Ally takes us through a lot of do's and dont's within our skin care routines. She also dives deep with us about her take on the "clean beauty movement" that is so popularized now in mainstream and commercial skin care! How marketing can take advantage of an innocent consumer, most times we don't know where to splurge on a purchase or save! Ally gives us all the tea, and lets us into her own skin care journey and deep passion for continuing to help those around her achieve their best skin. Sit down and get semi - serious with us on today's episode!

Wir begrüßen unseren ersten Gast im AUF EWIG WINTER Podcast! Nina Petrischenko (@ninovitsch) hat in Berlin Produktdesign studiert und zum Ende ihres Studiums ihre Leidenschaft fürs Tätowieren entdeckt. Ihre Arbeit sticht durch extremen Realismus und Detailverliebtheit hervor - und das, obwohl Nina erst seit knapp zwei Jahren tätowiert. // Derzeit macht sie eine Ausbildung beim renommierten Stuttgarter Tattoo-Studio "Mommy I'm Sorry" zur Tätowiererin. In unserem Gespräch über Leidenschaft, Handwerk und Kreativität sprechen wir unter anderem darüber, wie genau so eine Tätowierer*innen-Ausbildung aussieht, welche Voraussetzungen man dafür erfüllen sollte und welche Rolle Social Media in der Branche spielt. // Willkommen Nina Petrischenko im AUF EWIG WINTER Podcast #4! // Photo: @hi_its_elisa

Delightful and glamorous comedian JC Coccoli explains to us that makeup is your art coming through on your face. Plus, healing your body of psoriasis, pretty little lippies, being a comic while listening to your body, enjoying the process of finding your perfect routine, being your own scientist, and how brown eyes will save your life! For an extended version of this episode, head over to Stitcher premium! And for a list of everything discussed in this episode, visit www.natchbeaut.com.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

The 20th episode!!! In this episode, we discuss the United States Space Force, Beyonce, Chris Hardwick, Luke Cage, and the amazing breakthrough of "E-Dermis" US Army ROTC is our Sponsor! Links: Reference: https://www.webmd.com/a-to-z-guides/definition-amputation#1 https://www.sciencedaily.com/releases/2018/06/180620171004.htm

Professor Susan Anderson shows you the microscopic structure of the largest organ in the body - the skin. All you need to know about the structure and the cells of the skin and associated glands and hairs. Great for learning, revising for exams or if you're just interested to see what you look like down the microscope

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.

In this episode, Lauren peels back the layers of your body’s largest organ. Get ready to talk connective tissues, injuries, bacteria, anthropodermic bibliopegy, and more! [Some parts not for the super-squeamish–but Julia sat through the whole recording session, so you are probably okay.] Later, enjoy* a quiz called “By the Skin of Your Teeth (Bible Trivia)”! . [* alternately, by “enjoy,” we mean “feel bad about forgetting everything you ever learned in CCD or bible study”] . . . [Music: 1) Hole, “Celebrity Skin,” 1998; 2) Frau Holle, “Ascending Souls,” 2017. Courtesy of Frau Holle, CC BY-NC 3.0 license.]

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.

Back after a couple of weeks of technical difficulties, the gents are joined by the Jewish playboy, Benjamin Harris Rosen, and they discuss everything from watch tans to candle lit showers. #chafeNcheese #STBpodcast #tellyourgrandma @chafencheese on FB | Insta | Twitter www.chafeNcheese.com

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Welcome to the Idries Shah Foundation podcast, practical psychology for today. This weekly podcast features selections from Idries Shah books, as well as original recordings. It has been made available by The Idries Shah Foundation, and is voiced by David Ault. This episode features selections of The Dermis Probe, by Idries Shah.  

Skin 101 Your skin is the largest organ of your body. It has 3 jobs: Protection, Regulation, Sensation Natural complexions are being viewed as more beautiful than a "tan". 3 Layers Epidermis (above skin) - waterproof, gives you your color, the layer we see Dermis-Epidermis junction - a protein layer containing collagen and elastin to give skin flexibility and stretchability Dermis - where your glands, hair follicles, and nerves are Hypodermis - (below skin) - houses adipose tissue for insulation, and blood vessels The Epidermis is made up of several separate layers based on what is happening in the cell's lifetime. The basement membrane sits right on top of the Dermis-Epidermis junction, made up of fibrous proteins to be a solid foundation. Epidermis Layers Basal Layer - Keratinocytes (makes Keratin) and Melanocytes (makes Melanin) - stem cells. Spinous Layer - Cells are actively dividing and getting squished together Granular Layer - Cells start making the proteins (keratin or melanin) that they are coded to make and it fills up all the intracellular space; the organelles of the cells get crowded out Lucid Layer (Clear) - Keratinized cells are clear; Melanin-filled cells are colored. Cells are officially dead.  Cells become coated in a hydrophobic (afraid of water) oil. Hard Layer  - cells are tightly packed together and dry; the layer we can touch. These cells are being continuously produced and shed off and replenished because the skin takes a lot of abuse. Deeper Stuff UV light from sun or tanning beds (heaven forbid!) stimulates melanocytes to divide faster and create more melanin (because melanin is reflective and keeps UV rays away from the important cells).  This is how a tan is created.  But during times of huge exposure, like tanning beds, there's not enough melanin to keep all the UV rays out so those rays can wreak havoc on the collagen and elastin proteins.  This is why over-tanned skin ages faster. Hydrating makes sure that the living and dividing cells are plump and as healthy as possible so when they move to the next layer, they are well nourished. Protection: keeps dirt and bacteria out; protections from UV radiation Regulation: releases sweat to cool the body's temp; subtly moves blood vessel closer or farther away from the surface to either cool the warm blood (like after exercise) or keep it warm (like in the winter). Sensations: allows you to feel things that touch you or come close to you. I can't seem to find any free footage of the original episode (Season 1, Episode 3) without having to sign up for a free streaming service.  The Mythbusters did a "revisit" of their Goldfinger episode.  Netflix the original, if you can. Connect with me Support us on Patreon *NEW* Join the Pharmacist Answers Podcast Community on Facebook Subscribe: iTunes, Stitcher, GooglePlay, TuneIn Radio Like the Facebook page Music Credits:  "Radio Martini" Kevin MacLeod (incompetech.com)  Licensed under Creative Commons: By Attribution 3.0  http://creativecommons.org/licenses/by/3.0/

flipping things from last week's summer mix, we go deep inside with some choice ambient and experimental sounds from You're Me, Tim Hecker, Andy Stott, and the passenger, before slowly rolling into some 4 on the floor techno variations. At once intimate and in your face.

https://es.wikipedia.org/wiki/Carlos_Eduardo_TroconisMomento histórico e inolvidable en mi carrera, el haber podido entrevistar a este icono del rock, de la música y la contracultura venezolana y latinoamericana. Genio, rebelde, creativo y rocker. Moriría cuatro años más tarde.

In this very special episode, Amy and Paul discuss tattoos. Direct MP3 Download SHOW NOTES The Tom Petty album cover upon which Amy’s tattoo is flagrantly infringing is for “Wildflowers”: A far-better-researched history of tattoos in America. For more discussion on Larry Bird’s shorty-shorts, see episode #16, “Just the Bottoms”. Steve-O’s amazing portrait back tattoo: […]

Programme de Richard GARET pour webSYNradio : Dermis project, inédits. Le projet Dermis met l'accent sur des pratiques d'atelier et des travaux sonores en cours ; encore invisibles, inaudibles, et inconnus du grand public . L'intention de Richard Garet pour ce projet a consisté à s'éloigner des conventions en invitant des artistes confirmés à présenter un travail inachevé ou un fragment... 7h de programme et de contact avec Alfredo Marin, Andy Graydon, Ben Owen, Bonnie Jones, Brendan Murray, Byron Westbrook, Carver Audain, Christopher DeLaurenti, Daniel Neumann, David Schafer, David Velez, Doron Sadja, France Jobin, Gil Sansón, Gill Arno, Jesse Kudler, Jim Haynes, Katherine Liberovskaya, Lesley Flanigan, Maria Chavez, Martin Crecium, Melissa F. Clarke, Mv Carbon, Richard Garet, Sabisha Friedberg, Seth Cluett, Stephanie Loveless, Tristan Perich, Tristan Shepherd, Victoria Keddie, Wolfgang Gil.

Die vorliegende Dissertation befasst sich mit den durch S-Lost-verursachten Symptomen in der Haut, die zunächst durch starke Blasenbildung und später durch eine verzögerte Wund-heilung charakterisiert sind. Bei S-Lost handelt es sich um einen chemischen Kampfstoff, der erstmals im ersten Weltkrieg zum Einsatz kam und bis heute in vielen internationalen Kon-flikten großen Schaden anrichtete, obwohl der Gebrauch schon 1925 durch die Genfer Konvention verboten wurde. Aktuell stellt S-Lost zudem eine Bedrohung durch terroristische Aktivitäten dar. Da für S-Lost-induzierte Verletzungen bislang keine spezifisch wirksamen Behandlungs-methoden verfügbar sind, besteht großes Interesse an der Aufklärung der dem Krankheitsbild zugrunde liegenden molekularen Pathomechanismen, um daraus Rückschlüsse auf besser ge-eignete therapeutische Maßnahmen ziehen zu können. In unseren ersten Experimenten wurden als mögliche Auslöser der Blasenbildung die Expression und Sekretion ausgewählter Matrix-Metalloproteinasen (MMPs) und deren endogenen Inhibitoren, den tissue inhibitors of matrix metalloproteinases (TIMPs) in einem 3D-Haut-modell und in verschiedenen Zelltypen der Haut (Keratinozyten, Fibroblasten, mikrovaskuläre Endothelzellen, mesenchymale Stammzellen, monozytäre Zellen, PMN-Granulozyten) sowohl in Mono- als auch in Mischkultur untersucht. Unter Verwendung von molekularbiologischen und proteinbiochemischen Methoden wie qRT-PCR, Zymographie und Western Blot gelang der Nachweis, dass MMPs - insbesondere MMP-9 - nach Exposition der Zellen (v.a. Fibroblasten und monozytäre Zellen) mit S-Lost deutlich hochreguliert wurden. Zu Erhärtung der Annahme, dass MMP-9 durch Degradation der Basalmembran zwischen Epidermis und Dermis zur Blasenbildung beiträgt, konnte als Pathomechanismus nun erstmals eine parakrine Stimulation von Fibroblasten durch S-Lost-behandelte Keratinozyten identifiziert werden, als deren Folge eine vermehrte MMP-9-Sekretion resultierte. Darüber hinaus zeigte sich in weiteren Versuchen unter Verwendung des sog. Scratch-Assays und eines Transwell-basierten Invasionsassays, dass das Migrations- und Invasionsverhalten der Fibroblasten in Gegenwart des konditionierten Mediums der S-Lost-behandelten Keratinozyten positiv beeinflusst wurde. Aus klinischer Sicht sprechen diese Erkenntnisse für neue therapeutische Ansätze, die darauf beruhen sollten, die S-Lost-induzierte, auf proteolytischer Aktivität basierende Blasenbildung der Haut durch Applikation spezifischer MMP-Inhibitoren zu behandeln. In einem weiteren Projekt wurde die verzögerte Wundheilung als spätes Symptom der S-Lost-Vergiftung auf zellulärer Ebene untersucht, bei der eine eingeschränkte Re-Epithelialisierung der betroffenen Hautstellen beobachtet wird. Sowohl für den Prozess der Wundheilung als auch für die stetige Erneuerung der Haut werden epidermale Stammzellen benötigt, die für die Bildung von Keratinozyten verantwortlich sind. Diese unipotenten Progenitorzellen befinden sich in der basalen Schicht der Epidermis und sind in der Lage zu proliferieren und anschließend terminal zu differenzieren. Um eine Beeinflussung dieser Prozesse durch S-Lost zu untersuchen, wurden primäre unreife Keratinozyten (NHEK) verwendet und hinsichtlich ihres Differenzierungspotenzials untersucht. Dabei erwies sich S-Lost als potenter Induktor der Differenzierung von NHEK, was durch Bestimmung der Expression typischer Markerproteine wie Keratin-1, Involucrin und Loricrin gezeigt wurde. Die Induktion des Reifungsprozesses war sowohl von einem Rückgang der Proliferation als auch von einer verminderten Migrationsrate der Zellen begleitet. Die eingehende Analyse von mitogen-activated protein kinase (MAPK)-Signaltransduktionswegen führte zu der Erkenntnis, dass die Aktivitäten von p38 und ERK1/2 gegenteilige Rollen im Differenzierungsprozess einnehmen. Studien mit spezifischen Inhibitoren der MAPK be¬legten, dass p38 für den Reifungsvorgang in NHEK essentiell ist, während ERK1/2 diesem entgegen wirkt. So konnte durch Blockade von p38 die von S-Lost ausgelöste Differenzierung der Zellen verhindert werden. Ebenso war es durch diese Behandlung möglich, die von S-Lost stark beeinträchtige Migrationsfähigkeit der Keratinozyten wiederherzustellen, welche mit einer erhöhten MMP-1-Expression einherging. Davon abgeleitet erscheint es therapeutisch sinnvoll, selektive p38-Inhibitoren für die Behandlung von Wundheilungsstörungen nach Exposition der Haut mit S-Lost einzusetzen. Zusammenfassend erbrachten unsere Studien also den Nachweis, dass der S-Lost-induzierten Blasenbildung (als frühes Symptom) die spezifische Induktion der MMP-9 zugrunde liegt. Darüber hinaus konnte erstmals eine verfrühte Differenzierung in unreifen Keratinozyten der Haut (als mögliche Ursache für die verzögerte Wundheilung) nachgewiesen werden, wobei die MAPK p38 bei der Initiierung des Prozesses von entscheidender Bedeutung ist. Aufgrund dieser Resultate empfiehlt sich eine kombinierte Applikation von Inhibitoren der Aktivitäten von MMP-9 und p38, wobei der Einsatz jedoch zeitlich abgestimmt erfolgen sollte, um pathologische Effekte (Blasenbildung bzw. Differenzierungsinduktion in Keratinozyten) zu blockieren, ohne die positiven Auswirkungen von MMP-9 und p38 auf die Heilung (Migration von Immunzellen und Keratinozyten bzw. Reepithelialisierung) zu hemmen.

The Dermis can be taken from the feline by various means.  This one might be less painful (but you'd really have to ask Tiddles). 'E's between the 'A's in the second part seem the ease the journey a bit.  Just a notion but it might sound normal enough in a crowded pub.

Die Differentialdiagnose entzündlicher Hauterkrankungen setzt seitens des Dermatologen ein hohes Maß an klinischer Erfahrung voraus. Labortechnische und histologische Untersuchungsverfahren sind dabei nur eingeschränkt hilfreich. Ausgehend von der Annahme, dass erstens das atopische Ekzem ein krankheitsspezifisches Mikromilieu in der Epidermis und Dermis aufweist und dass sich zweitens dieses spezifische Mikromilieu im Phänotyp der immunkompetenten CD1a positiven epidermalen dendritischen Zellpopulation widerspiegelt, wurde seit 1995 ein Verfahren zur Immunphänotypisierung von Langerhans Zellen und IDEC entwickelt. Es konnte gezeigt werden, dass das atopische Ekzem durch eine hohe Expression des hochaffinen IgE-Rezeptors (FceRI) bei niedriger Expression des IgG-Rezeptors FcgRII auf den dentritischen Zellen der Epidermis hoch sensitiv und spezifisch von anderen Dermatosen abgegrenzt werden kann. Ziel der vorgelegten Arbeit war es, die standardisierte Phänotypisierung CD1a positiver epidermaler Zellen so zu erweitern, dass neben dem atopischen Ekzem auch die Diagnose anderer entzündlicher Hauterkrankungen möglich wird. Es wurden 296 Patienten mittels standardisierter Phänotypisierung epidermaler dendritischer Zellen untersucht. Bei 192 Patienten konnte nach Abschluss aller klinisch diagnostischen Untersuchungen eine eindeutige Diagnose gestellt werden, so dass die an diesen Patienten erhobenen Phänotypisierungsdaten für die Analyse krankheitsspezifischer Veränderungen im Oberflächenmarkerprofil von Langerhans Zellen und IDEC herangezogen wurden. Die Patienten verteilten sich auf 8 Gruppen: Normale Haut (n=31); Atopisches Ekzem (n=59); Psoriasis (n=41); Allergisches Kontaktekzem (n=23); Kontaktekzem bei atopischer Diathese (n=14); Lichen ruber (n=6); Mycosis fungoides (n=10) und Nummuläres Ekzem (n=8). Es konnte gezeigt werden, dass der prozentuale Anteil epidermaler dendritischer Zellen in Abhängigkeit von der Diagnose variiert und dass die bei allen entzündlichen Dermatosen nachweisbare Vermehrung epidermaler dendritischer Zellen vorrangig auf eine de novo Einwanderung von IDEC in die Epidermis zurückzuführen ist. Das wesentliche Ergebnis der vorgelegten Arbeit ist die Erweiterung der diagnostischen Phänotypisierung auf die Psoriasis und das allergische Kontaktekzem. So konnte die Psoriasis durch eine Ratio von CD64/CD11b auf IDEC sinnvoll abgegrenzt werden. Das Kontaktekzem war mittels einer Ratio aus E-Cadherin/CD86 auf Langerhans Zellen zu identifizieren. Die Gruppe der Patienten mit Kontaktekzem bei atopischer Diathese wurde durch die Ratio E-Cadherin/CD80 auf IDEC erkannt. Die bereits für das atopische Ekzem publizierte Ratio FcRI/CD32 auf allen CD1a positiven Zellen wurde mit der gleichen Ratio, ermittelt nur für IDEC, verglichen. Eine Verbesserung der Sensitivität und Spezifität für die Diagnosestellung des atopischen Ekzems konnte hierdurch nicht erreicht werden. Die starke Expression von FceRI auf LC und IDEC kennzeichnet das atopische Ekzem. Typisch für das atopische Ekzem ist weiterhin die Expression von CD36 auf LC und IDEC. Die Psoriasis ist durch eine besonders starke Expression der Fcg-Rezeptoren auf IDEC gekennzeichnet. Darüber hinaus findet sich eine erhöhte passive Anlagerung von sCD23 an IDEC bei Psoriasis. Gegenüber anderen Diagnosen ist die Expression von CD11b und CD11c auf IDEC vermindert. Für das Kontaktekzem ist die im Vergleich mit anderen entzündlichen Dermatosen niedrige CD49d Expression auf LC kennzeichnend. Die Einführung neuer diagnostischer Algorithmen in die Phänotypisierung epidermaler dendritischer Zellen konnte das diagnostische Spektrum dieser Methode deutlich erweitern. Neben atopischem Ekzem und normaler Haut wurden auch Algorithmen für die Psoriasis und das allergische Kontaktekzem beschrieben. Die systematische Analyse weiterer Dermatosen mit epidermaler Beteiligung dürfte auch für diese Erkrankungen diagnostische Algorithmen aufzeigen, die das Mikromilieu der entsprechenden Krankheiten widerspiegeln. Die Phänotypisierung epidermaler dendritischer Zellen dürfte insbesondere im Rahmen klinisch-therapeutischer Studien vermehrt zur Anwendung kommen, da mit dieser Methode eine objektive, quantitative Untersuchung einzelner behandelter oder unbehandelter Hautareale im zeitlichen Verlauf möglich ist.