Podcasts about kbg

It's been a month, in that time we've had a few important webinars, published lots of wonderful content & attended BIO in Boston this week. Thank you Virginie for going to BIO https://www.linkedin.com/posts/virginie-mcnamar_bio2025-theworldcantwait-raredisease-activity-7341849619028430848-I_FD    Ambry was awesome https://www.linkedin.com/posts/graglia_syngap1-ambryknowsgenes-activity-7336183874890231809-Beua    CURE SYNGAP1 CONNECT https://curesyngap1.org/curesyngap1connect/   CAMP4 Update - Hear it from them, in our US or EU Webinar.  US https://curesyngap1.org/resources/webinars/106-srf-us-know-about-asos-before-syngap1-clinical-trials-camp4-case-study/ EU https://curesyngap1.org/resources/webinars/107-srf-eu-know-about-asos-before-syngap1-clinical-trials-camp4-case-study/ Amlexanox and Cool Science Amlexanox (Repurposed Readthrough Drug) https://curesyngap1.org/resources/webinars/webinar-108-fortuity-pharma-repurposing-nonsense-mutations/ Cool Science https://curesyngap1.org/resources/webinars/webinar-109-linking-syngap1-and-human-specific-genes-srgap2b-c-that-control-the-tempo-of-synaptic-development/ Inaugural New Family Webinar Saturday June 28th, 2025, 9 AM Pacific https://curesyngap1.org/resources/webinars/syngap-research-fund-quarterly-webinar-new-syngap1-family-orientation/  Tuesday Sept. 9th, 2025, 5 PM Pacific also already scheduled! https://curesyngap1.org/resources/webinars/webinar-105-syngap-research-fund-quarterly-webinar-new-syngap1-family-orientation/   STUDIES - MATTER  ORTAS (need many, 27 signed up, 8 completed.) https://curesyngap1.org/resources/studies/ortas-observer-reported-toileting-abilities-survey/  BEACON (need 7) https://curesyngap1.org/resources/webinars/98-dreem-eeg-headband-to-assess-sleep-eeg-biomarkers-in-syngap1/   “Dear Families, This is a brief update on the Communication abilities in Children with Genetic Conditions study. The Communication abilities in Children with Genetic Conditions study collected parent-reported data on communication ability from 113 families and direct speech and language data from 33 children. Data collection has now closed and research reports are in preparation for the three most successfully recruited conditions; KBG syndrome, SYNGAP1-related disorder, and differences in MED13L. While the study was initially open to a wider group of single-gene conditions, it was only possible to recruit full data sets and large enough samples to produce high quality research reports for these three conditions. While not all of the data collected from families will be included in the research publications, all of the data provided by families has been extremely valuable to the study. Where permission has been given, anonymised data will serve as valuable pilot data to support future funding applications for research on relevant gene conditions. We thank all families for their valued time and participation in the project. Further updates will share our research reports as they become available. With best wishes, Harriet and the Communication abilities in Children with Genetic Conditions study team.”   PRESS  JJ in MD https://www.linkedin.com/posts/curesyngap1_syngap1-curesyngap1-activity-7331703029949267969-7AeK/  Stories #34 with Jo Ashline https://curesyngap1.org/podcasts/syngap1-stories/  Warriors Santiago, Axel and Issac! https://curesyngap1.org/syngap-warriors/  Cafe SYNGAP1 with Dina from NY https://curesyngap1.org/podcasts/cafe-syngap1/dina/  NL45 https://mailchi.mp/curesyngap1.org/make-a-splash-for-syngap1-awareness-45   FUNDRAISING Sprint Blog is Epic https://curesyngap1.org/blog/sprint4syngap-raises-over-200k-for-syngap1-in-5th-annual-fundraiser/ MDBR just happened Four team members raised $15,795 so far. Thanks to Heather Mestemaker, Justin Albrecht, Aaron Harding, and Alicia Harrison. https://cureSYNGAP1.org/MDBR Harper $5k match! https://donate.curesyngap1.org/campaign/694764/donate Liam https://donate.curesyngap1.org/campaign/696438/donate Story https://donate.curesyngap1.org/campaign/695981/donate   Thank you for your support, still matching! https://donate.curesyngap1.org/campaign/693597/donate   Pubmed is at 24 (so less than one a week…) https://pubmed.ncbi.nlm.nih.gov/?term=syngap1&filter=years.2025-2025&timeline=expanded&sort=date&sort_order=asc   Harrison paper on early exons and inherited mutations is great… https://www.eurekalert.org/news-releases/1088068    Cunnane DCM is out and Ingo noticed! https://epilepsygenetics.blog/2025/06/20/revisiting-syngap1-through-a-disease-concept-model/  She spoke at SRF Conference https://www.youtube.com/watch?v=nXagMfYh9VA    SHARE BLOOD TO THE SRF BIOBANK AT CB! Read here for more information: https://curesyngap1.org/blog/fueling-research-syngap1-combinedbrain-biorepository-roadshow/    VOLUNTEER  Join us: https://curesyngap1.org/volunteer-with-srf/    SOCIAL MATTERS - 4,185 LinkedIn.  https://www.linkedin.com/company/curesyngap1/  - 1,380 YouTube.  https://www.youtube.com/@CureSYNGAP1    - 11,314 Twitter https://twitter.com/cureSYNGAP1  - 46k Insta https://www.instagram.com/curesyngap1/    NEWLY DIAGNOSED? New families have resources here! https://syngap.fund/Resources      Podcasts, give all of these a five star review! https://cureSYNGAP1.org/SRFApple   https://podcasts.apple.com/us/channel/syngap1-podcasts-by-srf/id6464522917    Episode 173 of #Syngap10  #Advocate #PatientAdvocacy #UnmetNeed #SYNGAP1 #SynGAP #SynGAProMMiS

*** Planuoji kelionę? Įsigyk Saily su 15 proc. nuolaida https://saily.com/protopemza *** *** Ieškai ratų? Ateik į Deals on Wheels https://dealsonwheels.lt/protopemza/ *** Aplaidumą vainikuojančios katastrofos – išskirtinai sovietmečiui pritinkantis bruožas. Labiausiai gaila, kad jos krėtė po supuvusiu sąjungos sparnu prevarta suvarytas šalis. Kalbamės apie garlaivį „Mayakovsky“, kurio likimas paskendo 306 km nuo Punsko – Rygoje. 1950 m. šimtus brolių ir seserų latvių nusinešė reklaminės kampanijos klaida, kuriai pagreitį suteikė atsainus sovietinis požiūris į gyvybę. Bet buvo ir išgyvenusių. Jurijus Krinycinas – vienas jų. Nors per Stachanoviečių šventę įvykusi garlaivio tragedija paliko vyrą gyvą, psichologinę Jurijaus sveikatą iki šiol skalauja Dauguva. Jurijaus protą temdančios psichozės netruko virsti serija žmogžudysčių.  Ar tikrai visos aukos buvo atsitiktinės? Galbūt pats Jurijus tebuvo KBG darbelių glaistymo įrankis? Jūsų laukia sovietinės pramogos, likimo išdaigos, daug besišlapinančių vyrų ir viena kita sąmokslo teorija.  Iliustracija: @tinymischiefs Muzika: Jay_You, Quetzalcontla, Setuniman, TheoJT, Victor_Natas, RobertMThomas, Universfield

Russia’s President Vladimir Putin celebrates 25 years in power this week, along with a Victory Day parade attended by leaders from around the world. We chart his rise to power, how his worldview has changed, and what we can expect from him next. In this episode: Mikhail Zygar (@zygaro), Writer & Author Episode credits: This episode was produced by Amy Walters, Sonia Bhagat, Ashish Malhotra with Phillip Lanos, Spencer Cline, Khaled Soltan, Khaled Soltan, Kingwell Ma, Remas Al Hawari, Mariana Navarette, Kisaa Zehra, and our guest host, Natasha Del Toro. It was edited by Sarí el-Khalili. Our sound designer is Alex Roldan. Our video editors are Hisham Abu Salah and Mohannad Al-Melhem. Alexandra Locke is The Take’s executive producer. Ney Alvarez is Al Jazeera’s head of audio. Connect with us: @AJEPodcasts on Instagram, X, Facebook, Threads and YouTube

Teorier sier at Trump har vært på russisk side siden 80-tallet. At han skylder Russland, mafia og KBG alt. Konspirasjonspodden tar en titt. Ansvarlig redaktør er Kristin Ward Heimdal. Hør alle episodene fra Konspirasjonspodden eksklusivt hos Podme. Prøv gratis på podme.com.

On this week's episode of Beautiful and Bothered, Johnny and Kevin analyze the TikTok ban and what it means for the USA and the Beauty Industry. They also discuss Avatar: The Last Airbender and the new season of The Traitors! Please also check out this article from Big Think, detailing the horrifying predictions of a KBG defector 39 years ago who predicted the state of modern America. Then ask yourself why Putin loves Trump so much... https://bigthink.com/the-present/yuri-bezmenov/ JOIN our PATREON Family: http://www.patreon.com/BeyondBothered

The Genetic Rare Syndromes Observational Cohort (GenROC) study aims to improve our understanding of how rare genetic conditions affect the way children grow, their physical health and their development. Through actively involving parents as experts in their child's condition, the study seeks to gather valuable insights and ensure that family experiences shape future research and care strategies. You can find out more about the study and eligibility criteria via the Bristol University website. In this episode, Jillian Hastings Ward, patient advocate and former Chair of the Participant Panel at Genomics England, is joined by Dr Karen Low, a clinical geneticist leading the study at the University of Bristol, who shares insights into its objectives, the importance of a co-production approach with families, and the vital data being collected in the study to improve support for these children and their families. We'll also hear from Lindsay Randall, a parent who discusses the journey of receiving a rare diagnosis for her child, highlighting the critical need for more comprehensive information and community support. "If you join GenROC, that data will be used to develop a growth chart for your child essentially and their genetic condition, so I'm really excited about it because I feel like that's a very concrete definite given now for all the families in GenROC, which is just brilliant." You can download the transcript or read it below. Jillian: Welcome to Behind the Genes Lindsay: Historically, there's been a significant absence of patient voice in rare disease research and development, and knowing that's changing, I think that's really empowering for families and to know that professionals and industry are actually listening to our stories and unmet needs and really trying to understand, and that offers much greater impact on the care and treatments of patients in the future. Jillian: My name is Jillian Hastings-Ward. On today's episode I'm joined by Dr Karen Low, Consultant Clinical Geneticist and Chief Investigator for the General Cohort Study, and Lindsay Randall, Paediatric Practice Development Nurse and founder of Arthur's Quest, which is a UK registered, non-profit, raising awareness for the ultra-rare condition: SLC6A1, developmental and epileptic encephalopathy. Welcome to you both. Today we'll be discussing the GenROC study, which is aiming to understand more about the health, development and valuing the experiences of children with neurodevelopmental conditions. If you enjoy today's episode we'd love your support. Please like, share, and rate us on wherever you listen to your podcasts. Thank you both very much for joining us today, Karen and Lindsay. There's a lot we want to cover, but first of all it would be great just to put a little bit of context around the Gen-Roc study. Karen, can you tell us a bit about what the study is aiming to do, who is eligible and why do you want them? Karen:  Thank you. And thank you so much for having me today, Jillian. So, the GenROC study, first to just explain to people what ‘GenROC' stands for. GenROC stands for the Genetic Rare Syndromes Observational Cohort Study. Just to give you some context about the study, I'm a clinical geneticist and most of my clinical work focuses on paediatrics, so I see children in my clinics and the sort of children I see generally are children with rare genetic syndromes. The last five to ten years we've got much better at diagnosing children with these rare conditions and that's because testing has got so much better. We can now do whole genome sequencing and we can do that on the NHS, which is amazing, children can get their tests as part of their clinical care, so it means that a lot more children are being diagnosed with rare conditions, about 2,000 per year in the UK. And the thing about that is, that I see these children in my clinics and I give their families that diagnosis. But the problem is for so many of these ultra-rare conditions, like Lindsay's family has, we sit there and we say to the family, “Well, your child has got ‘X' condition,” and we give them some information from maybe one or two publications and linked to a leaflet and a Facebook group. And then we say, “But really we don't know that much about this condition.” And they say, “But what is it going to mean for them when they are growing up or when they are adults? Will they be able to finish school? Will they be able to work? What is it going to mean?” And I have to shrug my shoulders and go, “I'm not really sure.” And as a geneticist and as a doctor and as a mother really, I just felt that wasn't good enough, and I found it really frustrating and I know that the families that I work with, that I look after, also find it frustrating and I wanted to do better. And I also found it frustrating that for many genes, researchers would publish two or maybe three publications about these conditions, and then they would move on to the next novel gene, and actually, the journals are a bit like that as well, they like novel things, they like new conditions, they like the next gene. And so, it means that actually data doesn't always carry on being gathered in these rare conditions, and there are a lot of them. That was another thing, I sort of felt that these conditions were being done a disservice and that we needed to do better, so that's where the whole idea of the GenROC study came from was my drive and desire to improve things for families and actually to work with families to improve that, and that's where so this is a very highly co-produced study and right from the outset I've involved parents in telling me what they wanted to know and I've got a very, very active PPI group, full of parents of children who have got rare genetic conditions, and also I'm really lucky to have a young adult who has a genetic neurodevelopmental disorder herself and they all tell me about essentially what I should do and what I shouldn't do. They tell me when I'm not doing enough or when I need to do something differently, so it's very highly co-produced, they're highly involved all along the way. So, children with a confirmed genetic diagnosis in a list of eligible genes which people can see on our website if they Google GenROC University of Bristol, we've got a very easy checker for eligible genes, but they are essentially the most frequently diagnosed genes in rare neurodevelopmental disorders. And if their child is under 16, has a confirmed diagnosis and doesn't have any other genetic diagnoses then they can go into the GenROC study, that's essentially the eligibility criteria. Jillian: That's really interesting. It's very helpful to hear the background and I think as a parent of a child with a very rare disorder hearing that the clinicians also recognise this gap and the sort of pause that happens once you have your initial diagnosis, is really helpful and really encouraging. Lindsay, can we turn to you next and can you unpack a little bit about what it meant for you to get a rare diagnosis for your child and what point on your family journey was that compared to where you are now? Lindsay: I think to get a rare diagnosis for us was difficult and challenging and I think the first kind of challenge that any family has is actually being well-informed by a paediatrician who is also well-informed, and that's not always the case. That can affect the way we acknowledge or accept a diagnosis and how we also access support and how we understand what more we can do to make more connections. We did have genetic counselling offered, but I think there are families out there who don't get genetic counselling offered to help them understand the child's diagnosis, and then there's a heavy reliance on the internet, and as you said, there's a lack of information out of there. A lot of conditions are newly diagnosed or they're very complicated genes to work with, or as Karen said, they've had a couple of papers and people have moved on. And I think that does cause an immense feeling of isolation. We were diagnosed in 2018, our son, our first child, and exactly as Karen said, it was a fairly quick appointment of, “We don't really know much about this condition at the moment, there's a couple of papers. We know of 34 children in the world at the moment with your condition. Here's a Facebook group,” which we did join. And it is overwhelming to be given a diagnosis that's delivered with such little hope I guess, finding sources of information that's valid and robust is challenging, not everyone knows how to do that or has a skillset to conduct searches of academic research and I think that clinicians could definitely do better in also signposting the kind of umbrella charities like Unique and Contact and Swan and patient organisations, because I know that would have been definitely helpful for us as a family to be able to have opportunities to connect with others. Jillian: Thank you. Our diagnostic journey has been a bit a similar in that we were diagnosed through the NHS, and that at the time my son was the first person diagnosed with his disorder in the whole of the UK so it was really a big question mark, it was a question of our geneticist saying, “Here's the three PDF articles that we know exist in the world about this condition. Can you read them and tell us whether you think that sounds like him in order for us to be confirming our diagnosis?” I very much hear what you're saying there about feeling lost in the wilderness. And we too joined a Facebook group quite shortly after we got our diagnosis, and at the time my son was among the older ones or certainly as time has gone by he has been among the older children, so it can be really hard to know what might happen next. I think that now as Karen was saying we're getting much better at diagnosing people thanks to all the extra testing that's happening, that happens much earlier in life than it has done in the past, but I think then it still leaves a gap in parents' understanding because you don't necessarily know what the next ten years might look like for example. And so, I think making connections with people who are in that age bracket can be really important, but it's very hard to do. So Lindsay, I'm conscious that your professional training as a nurse must have stood you in quite good stead when you were faced with a barrage of medical literature shortly after your diagnosis, but I think one thing that every parent shares is the desire to do the best for their child and especially in this world of rare disorders. There's a huge amount of energy that comes through the community I think, faced with the need to try and self-start and build these networks and connections for themselves. Is that something that you've seen in your community as your experience? Lindsay: Yes, definitely. I think we're a growing community and over the years of course more and more children and young adults have been diagnosed with a few older adults coming through. It is very much a global networking effort and parent/patient organisations have been set up in many countries now by parents of children with children with SLC6A1. I definitely think that drive to become an expert in your child's condition is a long journey and one of continual learning and actually a lot of families simply don't have a capacity to take that on, I think often the medical and scientific jargon is difficult to understand and that makes it challenging to access. And as you said, as a paediatric nurse, I at least have some existing skills to understand healthcare to read the research and speak with medical and scientific professionals with some confidence, but in some ways, that has increased the burden I've placed on myself to become an expert for my children and other children and families who are not in the same position as me. It does require a lot of dedication and time, and that does have implications on families because it's time away from our children and from home, and from the remnants of our lives that we desperately try to cling onto, to not lose all sense of ourselves. It's not often spoken about but I do see the strain it places on the families, as well where there's a lot of separation and divorce sadly in the rare disease communities, and often that's as a result of one parent's drive to be the expert, which seems to cause one parent to fulfil more burden of care and that fosters some level of resentment or sense of loneliness towards the other one. Jillian: There are some scary statistics out there around familial breakdown in this context, and it is something which there are so many factors at play, but it definitely seems to be quite widely recognised and definitely a problem. In terms of the time that people have to spend on liaisons with the research community and the clinical community, that could bring us quite nicely back into a question for you, Karen, about what kind of information the GenROC study is looking to collect from families, can you tell us a bit more about that, please? Karen: Yes, absolutely. As I said before, I've been very conscious of the sort of lives that our families are living, and listening to Lindsay, her story is very reminiscent of so many others and yours, Jillian. So I know families have about a gazillion hospital appointments, their children are often also very, very ill intermittently or a lot of the time, then they've got school stuff to deal with or they've got EHC plans to try and fight for. It's more than a fulltime job in itself just being a parent of a child with a rare disease and it's hard work, so me asking them to do anything else is asking a lot. Luckily, I find, with the families I work with, who are universally wonderful I should add, that they are actually just really enthusiastic anyway about research for their child's condition, and that's because there isn't enough information out there, so it's relevant and important to them. But because they have no time at all, and any time they do give is their own personal time when they could be finally putting their feet up and watching something on TV, I have to make it as low effort as possible. The questionnaire is all online, using a user-friendly and interface as we've been able to develop. It's very user-friendly, it takes 10-15 minutes to complete; they can come and go from the questionnaire as well. We only ask for one time point at the beginning, which is all the sort of stuff that most parents will be able to tell you off the top of their head as well, so they don't have to go looking for loads of information, apart from a height and a weight. Then later down the line we're going to ask for a second questionnaire, it's in the process of being finalised and again that will be the same amount of time, very easy to do, online, at their convenience. It was co-produced with the PPI group, they've tested it for me, I've had really good feedback and I've asked parents who are in the study as well for feedback. Everyone tells me it's not too difficult or burdensome for them to do. The secondary questionnaire has been very much informed by conversations with the parents that I had as part of a nest of qualitative interview study in GenROC, and that has driven that secondary questionnaire quite differently to what I thought it might be when we first set up the GenROC study. At the beginning I thought it might just be: have things changed for your child? Can you give us a bit more clinical data? But actually I realised that probably I will still gather that information, but they probably won't have changed that much within the timespan in the study because it will only be a year or two after they completed the first questionnaire, and actually I realised that it would be much more useful to look at the impact of the genetic diagnosis, look at how they're accessing services within the NHS, what sorts of services they are accessing, Impact on the family and also looking at priorities for families. So families have talked to me about what their priorities are in rare disease, both in service provision but also in research, and I really am a very strong believer that we need to be given the limited funding, we need to be doing the research that matters the most to the families, not to the researchers. What do families actually want us to look into? Actually, do they want us to be looking into behaviour and what strategies work best for example, rather than something else very medical – what matters the most? And so that's going to be a specific question in that secondary questionnaire, really trying to identify what matters to families the most and then how that can be translated into clinical research in the future. So I'm really interested to see what's going to come out of that. Lindsay: I think that sounds brilliant, Karen because I think historically there's been a significant kind of absence of patient voice in rare disease research and development, and knowing that that's changing, I think that's really empowering for families and to know that professionals and industry are actually listening to our stories and unmet needs, and really trying to understand, and that offers a much greater impact on the care and treatments for patients in the future and certainly it makes endpoints more relevant to families as well. Jillian: What kind of outputs are you going to be looking at? Karen: The height and weight, the reason I'm asking for that is really because we are trying to work on growth charts for children and that's because growth charts for children with rare conditions don't exist by enlarge, there are a very, very tiny number of rare syndromes or conditions that have their own growth chart. The problem is that most children with these sort of rare conditions that we're talking about are either quite small or quite big, and the problem is that the paediatricians look at their growth and they go, “Oh well, you're much bigger or much smaller than other children your own age, what shall we do about that?” and particularly the little tiny ones it causes lots and lots of concern, so quite often these sort of growth parameters mean that the paediatricians do lots and lots of tests or put feeding tubes down, or add lots of calories, so it can be quite invasive and interventional actually that sort of growth parameter. But actually, sometimes that's because of the genetic condition and no matter how much feeding you do it's not going to change anything. The difficulty is we don't know that for certain, and actually we need good growth charts where paediatricians can make that call, and conversely sometimes a child actually does need investigating and the paediatrician puts it all down to their genetic condition, and that's why we need these growth charts. So GenROC is aiming to gather growth data from all these children and then we're going to work closely with Decipher, which is a website that was developed through the DDD study, which already holds lots of data from that study, so we're building on the power of that study and we're going to be generating growth charts for all of these genes. We've developed a new method for producing growth charts for rare conditions where you've got small numbers of patients – that was never possible before, so we've already proven now for four conditions we can, so the next stage is using all the GenROC data, putting it into Decipher and coding it in. So, if you join GenROC, that data will be used to develop a growth chart for your child essentially and their genetic condition, so I'm really excited about it because I feel like that's a very concrete definite given now for all the families in GenROC, which is just brilliant. Jillian: And is that something which will be shared with the families individually? Karen: Really great question. I hadn't planned on sharing the growth charts individually with the families, but that's something I can also go back to my PPI group and discuss with them about whether that's something people would want, and also I have a newsletter which goes out every three months to the families, so I can certainly ask that question actually directly. It's going to be widely available, the growth charts, we're going to make sure that they're accessible to paediatricians and clinicians etc. but in terms of output to the study, definitely the growth charts, we're also hoping to have other clinically useful outcomes depending on the different genes that come into the study. We essentially have a cohort of children with rare conditions, everyone puts everything down to a specific genetic condition but we know that there must be other factors at play that influence how children do. And this is a really unique thing we're trying to do with GenROC actually, looking at aside from that genetic variant, that alteration, what other factors are influencing how children are doing? Because some of those might be modifiable, you know, or some of them there could be things that could be put in place to help improve outcomes. So I'm quite excited about that as well, because that's quite new and novel and not really been thought about in this context before, so that will be an output. And the other output is something that I'm working on with Unique, which is the rare disease charity who has worked with us on GenROC from the start, and they are involved in our PPI as well and that is going to be looking at a template, calling it a report at the moment, it's in very early days, but something that parents will be able to hold, it's going to have lots of drop-down boxes that can be tailored and modified for individual patients and children, which will be a bit of a guide that they can give to clinicians, professionals, education, telling them about their condition but also telling them on an individualised basis about what needs to be looked for in the future. Because parents tell me they are fed up of having to tell everybody about their child's condition constantly, all the time, over and over again. So what the point of this output would be is to try and ease that burden a little bit. This is very early stages but we're going to involved parents all along the way. Jillian: And is that something which builds on the hospital passport idea that we've seen emerging around the world over the last few years where parents can start off telling their child's story on their own behalf? Karen: So, it's come from my own lived personal experience of being a mother of a child with autism and I haven't really spoken about that publicly before, so it's something I'm saying for the first time. I have a child who has autism and I have had to navigate things like a DLA application form. Jillian: That's Disability Living Allowance. Karen: Yes, exactly, which is a horrendous form, it's the most horrible form to complete, probably apart from an EHCP plan form but it's a horrible form to complete, it's quite upsetting as a parent and it's also got millions of boxes that you have to fill in. But one of the things that really, really helped me when I was completing that was a charity who had come up with lots of drop-downs that you could select from that might be applicable to your child to help you complete this form. And so it made me really think, “Well, could we do something similar for our children with genetic conditions but come up with lots of dropdown options that might apply to their child in all sorts of different areas?” And that was the inspiration, it was that, and doing the qualitative study that I've already done with parents of children in GenROC who were telling me about how fed up they were of having to constantly tell everybody about their child's condition over and over again. Jillian: Yes, that's probably very helpful to empower families to use standard terminology across the different families because my own son has epilepsy as part of his condition but actually trying to describe what his seizures look like I'm not sure I'm using the right words to fit the right boxes to fit them into the right categories with the neurologist. So that level of standardisation is something that we definitely need embedded into the system in order for more people to be able to use this data more effectively, so that sounds very helpful. Lindsay, coming back to you, what are you hoping to get out of this study, or what are you hoping this study will do on your behalf for the world? What motivated you to take part? Lindsay: I think I would like to see all of the aims of the study realised and for the study data to be used to inform the development of standards of care for a wide range of conditions, those included in the study. I think it would be great if that information, as Karen said, is available not only to the participants but also to children diagnosed with those conditions in the future and also it's an opportunity to consider themes that are identified across the disease groups as that can also help inform future research and look at investigations into the mechanisms of disease and where actually therapeutics could treat maybe more than one disease at a time and increase potential for basket trials and early access programmes – thank you to Dr Karen Low and her team for conducting the project because it included a comprehensive list of rare diseases, it really does give parents and patients an opportunity to have a voice and to contribute, which is empowering, and it gives them a little bit of autonomy as well over their direction that science and research goes to. Jillian: Fantastic, thank you. Karen, can you tell us a little bit about the timeframe for the study? I realise that we haven't really touched on that so far. Karen: Yes absolutely, I'm aiming to recruit 500 children as a total. We're open at 22 sites across the UK. Coinciding with this podcast actually we've opened a second door for recruitment, so the way we've recruited so far has been through clinical genetic sites, which is the way we've done these sorts of studies in the past, like the DDD study. The problem is that that relies on clinicians identifying eligible patients and clinicians are very, very busy in the NHS. I have worked closely with Unique who have been doing a lot of publicity and the genetic alliance have done publicity as well for the study, so that's been one way of identifying eligible participants. And also just parent power through social media has been amazing. The second way we're going to recruit, and this is going to happen very soon, is through Genomics England. So, we are going to trial a completely novel way of recruiting to research through Genomics England and that is for Genomics England to identify eligible participants for GenROC and this would have been through the 100,000 genome study and then they're going to send them invite letters, inviting them to take part. So that's the next phase of recruitment, I think if we have more than 500 then that will be great too, we'll be able to include those comers too, so that's not a problem. But we don't know whether this will work or not in terms of a way of recruiting to research, this is completely new for Genomics England and I'm a bit of a guinea pig if you like through the GenROC study, but I was quite willing to be that guinea pig because I thought it might increase access. So there will be some parents who have not been told about GenROC who have not heard about it, and who would love to take part, so I feel like this is the way of really widening that net as wide as possible. Jillian: I think that is a challenge isn't it, especially in rare disease – there's no point doing a public broadcast about an initiative because you're going to hit so few of the people that you're interested in, so actually how you access the community is the first challenge and I'm really pleased that Genomics England will be able to help you there because I think that is a very useful route through. I think it will probably be quite reassuring to quite a lot of families who were on the 100,000 Genomes Project who have got a diagnosis of one of the conditions that you're interested in, and are now perhaps subsequently in the fallow period after you have a diagnosis, wondering what happens next, so I can imagine it might be quite good news for some of them at least that they are now being invited to do something further. And the reason that you're building forward and you don't want people who are currently in the deciphering developmental disorders study is because you're already using their data through another source, is that correct? Karen: Exactly. So absolutely, I don't want anyone to feel that I don't want them, that's really not the case. I do want them but we have their data already from Decipher, so we're building on the DDD data already, so they're already contributing which is just the beauty of it, because that's what we should be doing in rare disease, we should be building on previous research because you know, you don't want to be trying to reinvent the wheel. Jillian: Agreed. So if someone is listening to this and has a child with a rare developmental disorder and they are interested in finding out more, what are the steps they need to take? Karen: If they Google Bristol University, GenROC, they'll come straight to the webpage and everything is on there. There's a link that they can sign up, the patient information leaflet's there, the eligible gene list is there, all the information they need, including our email address. Jillian: And is there an upper age limit for recruitment? Karen: Yes, children have to be under 16 and that's because once they get to 16 many of these conditions have associated learning difficulties, and it's just very much more complex to try and recruit young adults, young people, with learning difficulties and given it was a cohort study we felt it was going to be too difficult at the moment. Saying that, I have a huge interest actually in how these conditions present in adulthood, and I'm actually conducting a much smaller study at the moment in KBG syndrome, looking at adults, and so I hope that my future research career will allow me both to follow-up the children in GenROC, so that would be my vision but also to be able to take this forward for other adults with rare conditions, that's my aim and goal in the medium to long-term, so watch this space for that. Jillian: That sounds very exciting, thank you. Lindsay: I think I would like to say to Karen that I really like the sound of the idea of following patients up into young adulthood and adulthood, as you said, that is definitely a kind of an unknown area in lots of the rare diseases, especially in our condition, SLC6A1, it was mutation and the disease was only really discovered in 2015, so it is fairly new and we have very, very few young people and adults coming through and being diagnosed and connecting with the rest of the community. So, being able to understand the trajectory of conditions better and especially conditions where actually the presentation it's quite a spectrum, and so the long-term outcomes for people with SLC6A1 can look quite different, so it's good to collate more information about that I think. Karen: I think it's really important, so that's definitely where I'm looking to for the future with GenROC and more widely, I think it's just something I'm really interested in and has huge relevance for parents and families. Jillian: Well, I think we need to wrap up there but thank you both very much Dr Karen Low and Lindsay Randall for joining me today as we've been discussing the GenROC study, and how the study aims to improve understanding of how rare genetic syndromes affect the way children grow, their physical health, their development, but also how the patient and parent communities can work more closely with researchers to end up delivering something which is of a huge benefit to everybody. If you would like to hear more about this, please subscribe to ‘Behind the Genes' on your favourite podcast app. Thank you for listening. I've been your host, Jillian Hastings Ward. This podcast was edited by Bill Griffin at Ventoux Digital and produced by Naimah Callachand.

On this episode of CoRDS Cast, Polly sits down with Brianna Dose with the KBG Syndrome Association. Brianna is not only a strong advocate for her community but she also has a daughter with this rare condition. While being a pediactric nurse in neurology, she was put in the exact postition she needed to be to help her daughter and fight to find answers. To learn more about the KBG syndrome association, please visit: kbgsyndrome.org

In deze aflevering van NACpraat Radio blikken Robert-Jan, Joeri en Marcel zonder de korte vakantie vierende Leon terug op de laatste twee play off wedstrijden tegen Roda JC (0-5) en FC Emmen (1-1). Pepijn van de Merbel maakt een volwassen indruk. Martina moet heel hard sorry roepen. En Lucassen gaat voorop in de strijd. Een terugkoppeling uit het eerste gesprek tussen de KBG en de STAK/RvC na het statement. Er zijn een paar jeugdteams gepromoveerd. De Loco's collecteren voor sfeeracties. Weer 3 nieuwe NAC Vrouwen! Tot slot een vooruitblik op de uitwedstrijd tegen FC Emmen.

Były dziennikarz, obecnie polityk kandydujący do PE, Andrzej Rozenek od lat ostrzegał, że w Polsce zniszczono kontrwywiad, osłabiono armię i przejęto służby do działania na rzecz partyjnych interesów. W rozmowie z Radosławem Grucą, w podcaście „Podejrzani Politycy Extra”, wraca do tematu wywołanego przez Donalda Tuska z trybuny sejmowej, czyli spotkań Jarosława Kaczyńskiego z agentem KBG, do których dochodzić miało na przełomie lat 80. i 90. w mieszkaniu na Saskiej Kępie.

Jeff is joined today by Craig Milsten. Craig has worked as an assistant District Attorney and the head of litigation at a large general practice law firm. For the last 18 years, he has been with Katherman Briggs & Greenberg (KBG) Injury Law. Craig is an experienced trial attorney and specializes in personal injury claims.  Both Craig and Jeff have teenagers who are exceptional performers and musicians. York's music community—especially the York Symphony and the Youth Symphony—have greatly influenced their children's musical development. You won't want to miss this discussion, which includes the remarkable musical journey of Craig's son, Andy. What You Need to Know  (04:12) Personal injury law is based on the concept of negligence and a reasonableness standard.  (04:41) Injuries due to negligence can have financial, medical, and emotional consequences.   (07:00) Before joining KBG Injury Law, Craig considered KBG to be the gold standard. Being recruited was an opportunity too good to pass up.  (08:16) Starting a legal career in the DA's office provides terrific career experience. There is no better way to learn the rules of evidence, the rules of procedure, and how the courtroom works.  (09:55) Only a small number of civil cases go to trial. When they do, they can be years in the making and require a tremendous amount of work. (12:20) The goal with every civil claim is to try to resolve it outside of court. A claim only becomes a lawsuit when the plaintiff's idea of a fair resolution doesn't match the defendant's idea.   (12:39) There are risks in going to trial. It can take a long time to get to the courtroom. A trial is typically more expensive. There is also the risk of unexpected outcomes. (15:05) Craig's younger son is a terrific singer and actor, heavily involved in musical theatre. Craig's older son, Andy, is 19 and on the autism spectrum. Currently, he is finishing his first semester as a piano performance major at West Chester University. His story is amazing!     (27:26) Visit the KBG Injury Law website at www.resultsyoudeserve.com.    About Bellomo & Associates Jeffrey R. Bellomo, the founder of Bellomo & Associates, is a licensed and certified elder law attorney with a master's degree in taxation and a certificate in estate planning. He explains complex legal and financial topics in easy-to-understand language. Bellomo & Associates is committed to providing education so that what happened to the Bellomo family doesn't happen to your family. We conduct free workshops on estate planning, crisis planning, Medicaid planning, special needs planning, probate administration, and trust administration. Visit our website (https://bellomoassociates.com/) to learn more.   LINKS AND RESOURCES MENTIONED Bellomo & Associates workshops:https://bellomoassociates.com/workshops/ Life Care Planning The Three Secrets of Estate Planning Nuts & Bolts of Medicaid For more information, call us at (717) 845-5390. Connect with Bellomo & Associates on Social Media Tune in Saturdays at 7:30 a.m. Eastern to WSBA radio: https://www.newstalkwsba.com/ X (formerlyTwitter):https://twitter.com/bellomoassoc YouTube: https://www.youtube.com/user/BellomoAssociates Facebook:https://www.facebook.com/bellomoassociates Instagram:https://www.instagram.com/bellomoassociates/ LinkedIn:https://www.linkedin.com/in/bellomoandassociates WAYS TO WORK WITH JEFFREY BELLOMO Contact Us:https://bellomoassociates.com/contact/ Practice areas:https://bellomoassociates.com/practice-areas/    

In most major works of history, the "intelligence dimension" has been badly lacking. Enter Calder Walton, a scholar at the Harvard Kennedy School and author of "Spies: The Epic Intelligence War Between East and West." The Cold War did not begin after 1945, Walton argues, but rather the Soviet Union had been at war with the West since its inception, waging an intelligence onslaught designed to steal government secrets and commercial and technological advancements. And the Cold War did not end with the USSR's disappearance. The Kremlin continued to attack its enemies in the West. In this episode, Walton discusses his riveting book and its relevance to the new U.S.-China conflict. For the past century, intelligence services authored stories of human drama more compelling than anything found in a spy novel, replete with assassinations, election meddling, and nuclear close-calls.

Matt's dealing with a power outage in the neighborhood, so we clear the mailbag and enjoy some deep dive questions. Of course, also, Joe Knows Turf. Mailbag: Jeremy's question about damage to Zoysia (thread on TLF). JFarm's question about reno timing JKT: Using diesel fuel to playground turf at the daycare. (JKT - 01.png) Prepare for Fall Overseeding Summer Stripeaction (One, Two, Three) Member Questions: DClausen - tips on maximizing KBG germination in NY. Brent - questions about Cool Season in Western MA. Wood Chopper - Cool Season 'cides. Chris - Questions about billing side on turf management. Chuck - Ornamental question about Magnolia Scale. Special Thanks to Our Co-Producers: 6r33k633k Busy Beez's Turf Benjamin Mossing Lonegoose Turfology Jesse Bousquet Jr Jbartleyw Outsidefire Barthoda Ryan Danescu Tifway Lawn NateKrez harperexplores bwerthmann Mtech LCS Turf LTK Trucking & Freight Nreyes LW50 Sumbeach Lush Lawns 813King matix wfcook webcivilian Zach_H Kennard SchaneyTurf87 MattMac1r Loonie Josh1604 NeilOB Fenix Lawn Care Halpeet SeñorLawn toddskill GuardWellDFW JonzyJones Dmiller MarkBodiford Wade Hustad fyns 12k_ dclausen Owen Kluth

Todos los especialistas coinciden en señalar a Kin Philby como uno de los grandes -para algunos, el más grande- espías del siglo XX. Trabajó como agente secreto para el MI5, pero después de pasar por la Guerra Civil española, acabó por convertirse en espía del KBG, servicio secreto al que pertenecía, aunque los ingleses creían que eran "fiel" a Londres. 

Brian Strong is an attorney with KBG Injury Law. Jeff and Brian met when Brian sponsored a group of young lawyers, including Jeff, to be admitted to practice before the U.S. Supreme Court. That was nearly 20 years ago. Today, the friends get together to talk about the importance of specialization, the courtroom experience, alternatives to jury trials, and the pride that comes from giving back to your community. Key Takeaways  (00:19) – Collegiality in the legal profession Good lawyers are collegial while also being a zealous advocate and problem solver for their clients  You can be both a tough competitor and a good person (05:26) – Why injury law? Brian served as a law clerk and then as a prosecutor Eventually he realized he wanted to help victims  In about 90% of cases, he represents individuals against powerful insurance companies Brian's goal is to level the playing field for the individual  (09:38) – The scope of KBG's practice  Brian and other attorneys at KBG specialize in personal injury (PI) cases, e.g., car accidents, slip and falls, injury due to negligence, etc.  Other attorneys at the firm handle worker's compensation claims and Social Security disability In most cases, clients benefit when they work with lawyers who specialize in a particular area of the law (14:23) – Alternatives to jury trials These days, PI cases are settled less often by jury trials and more by a process known as alternate dispute resolution (ADR) ADR can include mediation, arbitration, or other means that enable faster resolution without a trial ADR also tends to be less expensive During the pandemic, the court system learned to conduct business using remote access technology (i.e., Zoom)  Today, Zoom is still used frequently  (18:16) – Being in the courtroom Being in the courtroom gets the adrenaline pumping Preparing witnesses, putting on your game face, and being in front of a judge takes special training and skills It can be better for the opposing parties and their attorneys to find a resolution without a judge (21:40) – Serving the community In 2013, Brian's firm started the KBG Community Fund in conjunction with the York County Community Foundation  This donor-advised, investment account enables KBG to support local charities KBG has contributed nearly $250,000 to the fund and has awarded almost $200,000 in grants Grantees have included the York Little League, Susquehanna Service Dogs, the Jewish Community Center, the York Junior Symphony Orchestra, and others Links and Resources Mentioned KBG Injury Law  https://resultsyoudeserve.com/ or call 717-848-3838 York County Community Foundation https://yccf.org/ Bellomo & Associates workshops:https://bellomoassociates.com/workshops/ Life Care Planning The Three Secrets of Estate Planning Nuts & Bolts of Medicaid For more information, call us at (717) 845-5390. Connect with Bellomo & Associates on Social Media Twitter:https://twitter.com/bellomoassoc YouTube: https://www.youtube.com/user/BellomoAssociates Facebook:https://www.facebook.com/bellomoassociates Instagram:https://www.instagram.com/bellomoassociates/ LinkedIn:https://www.linkedin.com/in/bellomoandassociates Ways to work with Jeff Bellomo Contact Us:https://bellomoassociates.com/contact/ Practice areas:https://bellomoassociates.com/practice-areas/

Kim Philby's job is to uncover other people's secrets. But now, his oldest friend is on the verge of exposing his own. As two other Cambridge spies are unmasked, Philby's reputation comes under fierce scrutiny. And Nicholas Elliott is determined to find out whether his old confidante is also a KBG agent. Can Philby wriggle free of Elliott's sting operation and a government desperate to catch traitors?See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The KGB would stop at virtually nothing in its attempts to spread chaos and confusion in the west throughout the Cold War. From honeytraps and smear campaigns to spreading fake news, Mark Hollingsworth tells Spencer Mizen about the KBG's extraordinary attempts to destabilise its enemies. (Ad) Mark Hollingsworth is the author of Agents of Influence: How the KGB Subverted Western Democracies (Oneworld, 2023). Buy it now from Amazon: https://www.amazon.co.uk/Agents-Influence-Subverted-Western-Democracies/dp/0861542169/?tag=bbchistory045-21&ascsubtag=historyextra-social-histboty Learn more about your ad choices. Visit podcastchoices.com/adchoices

Rudolf Ivanovich Abel was one of the most integral agents of the KBG, the Soviet Union's most renowned spy network during the Cold War of the 1950s. He may have infiltrated Los Alamos labs and fed critical intelligence back to Moscow through the use of cloak-and-dagger techniques like sneaking microfilm in hollowed- out coins and dropping bundles of cash at lamppost hideaways. He kept it up until his cover was blown by an incompetent colleague who wanted to defect to the United States. This lead resulted in a frenzied search by the FBI to discover the identity and whereabouts of the spymaster. The month long stake out of his hotel in Manhattan leading to his eventual arrest and transfer to a Texas deportation facility where he was put under extensive interrogation. His three-month trial and guilty verdict for violating U.S. espionage laws resulted in 30 years in prison rather than the electric chair. The exchange for his freedom several years later involved the American Spy Francis Gary Powers. To discuss this story is today's guest Cecil Kuhne, a prominent litigator, who has long been interested in the world of Cold War. He is the author of KGB Man: The Cold War's Most Notorious Soviet Agent and the First to be Exchanged at the Bridge of Spies.

Enjoy your Daddy's love Prophet Ezekiah Francis | Berachah Prophetic Ministries Watch in English https://youtube.com/live/RJoX8SZXLvo Watch in Tamil (தமிழ்) https://youtube.com/live/j-EPC8IZ_K0?feature=share Watch in Hindi (हिंदी) https://youtube.com/live/KBg-5eg421o?feature=share Watch in Telugu (తెలుగు) https://youtube.com/live/K39Z3YANfXc?feature=share Watch in Malayalam (മലയാളം) https://youtube.com/live/u5E_V3vSn5E?feature=share Watch in Kannada (ಕನ್ನಡ) https://youtube.com/live/zjDo3bWc4cQ?feature=share

After her dramatic defection, Svetlana settles into her new life in America. She's an overnight millionaire, trading communism for capitalism — a bestselling author with the attention of the world. But everyone from her translator to the KBG to a new lover is driving her nuts!See omnystudio.com/listener for privacy information.

Abonne-toi à la chaîne du Warmup ICI ► http://www.youtube.com/c/LeWarmUpFM Description : Jeudi passé, SALIMO nous performe en direct son nouvel album accompagné de MISA, KBG et toute son équipe ! Bonne Émission ! #lewarmup #mtl Salimo ► https://www.instagram.com/5alimo14 Antony ► https://www.instagram.com/antonydagger/ Freddy ► https://www.instagram.com/freddy.lloyd/ - Lundi 8-9 AM - Mercredi dès MINUIT - Jeudi dès 22H30 À MINUIT En direct du 102.3FM --- Send in a voice message: https://anchor.fm/le-warmup-fm/message

Le rappeur KBG est de passage pour nous parler de son parcours et sa vision artistique.

This Kentucky Bluegrass can out perform conventional KBG with 50% less sunlight. I talk to the researcher.

Jack joins us from his home in Atlanta, Georgia. Jack grew up as Albrecht Dittrich in post-WW2 East Germany in “The Valley of the Clueless”. He was a youth leader for the communist party and a promising young academic when he was approached by the KGB and recruited as an espionage agent. Armed with a sharp curiosity, a penchant for learning languages and a strong sense of adventure, Jack's changed his life forever when he agreed to take on his mission. After several years of training in Europe, he was posted in New York City as a “sleeper agent”. He spent many years working and educating himself as a regular dutiful US citizen would and eventually built a legitimate career and had a (second) family while living his American life. He found himself deciding between choosing to leave his new family and return to the KGB fold in Europe or leave the KBG at great expense and live out his life as an IT executive and father (spoiler alert: the FBI eventually caught up with him). We discuss what belief systems, elitism, “slow decontamination”, fear, narcissism, cowardice and heroism all mean to him. We ruminate about the immense power of (a lack of) a mother's affection and the moving love of a daughter and how those two forces book-ended his intensely unique human experience. To DONATE to the Behind Greatness podcast, please visit here: https://behindgreatness.org. As a charity, tax receipts are issued to donors. Behind Greatness IG: @behindgreatnesspodcast & @inspire_north Podcast Series “The Agent”: https://open.spotify.com/show/5DToOunQsM18OmGD5eVRXR Linkedin: https://www.linkedin.com/in/jackbarsky/ Website: https://jackbarsky.com/ FB: https://www.facebook.com/spybarsky  

Dan Payne joins the show to discuss the 1st Annual K9 Fundraising Event & Award Event 5/6 at Ap Cal, hosted by the Marine Corps League Fresno Detachment 14. The EU Commission President has called on its 27-nation bloc to among other things, ban oil imports from Russia, which would require a unanimous vote. Rumors are swirling that Putin's own former employer, the Russian security service and others, are growing tired of his failures in Ukraine and the impact on the economy. If rumors are true, Russia's Siloviki, along with former officers of the GRU, KBG and FSO are pushing hard to replace the president. A moment on Breaking the Chains.  See omnystudio.com/listener for privacy information.

Dan Payne joins the show to discuss the 1st Annual K9 Fundraising Event & Award Event 5/6 at Ap Cal, hosted by the Marine Corps League Fresno Detachment 14. The EU Commission President has called on its 27-nation bloc to among other things, ban oil imports from Russia, which would require a unanimous vote. Rumors are swirling that Putin's own former employer, the Russian security service and others, are growing tired of his failures in Ukraine and the impact on the economy. If rumors are true, Russia's Siloviki, along with former officers of the GRU, KBG and FSO are pushing hard to replace the president. A moment on Breaking the Chains.  See omnystudio.com/listener for privacy information.

We chat with Brandon (TurfCulture) about his POA & stressed KBG issues in St. Louis. He's even got a YouTube channel where he shares his journey with the world, including a recently acquired aerator! Check him out: https://www.youtube.com/c/TurfCulture/

History is full of what-ifs. What if in 1999 Russia's fading president Boris Yeltsin had handpicked someone other than Vladimir Putin to be his successor? What we do know is that Putin and his ruling circle steered Russia toward autocracy, and 22 years later the former KBG lieutenant colonel still rules with dictatorial powers. In this episode Julie Newton, an expert on Russian history and politics at Oxford University, discusses the set of circumstances that led Yeltsin to make his fateful choice, and the many reasons why the renewal of authoritarianism under a powerful state -- at odds with liberal Western traditions -- was not inevitable.

Mitä Kekkosen aika oli ja miten Suomen ja Neuvostoliiton välinen YYA-sopimus sai alkunsa? Minkälaista ulkomaanpolitiikkaa Suomessa on tehty 70-, 80- ja 90-luvuilla ja mikä vaikutus Neuvostoliitolla ja KGB:lla eli Neuvostoliiton valtiollisella turvallisuuspoliisilla on ollut Suomen ulkopolitiikkaan? Minkälaista on ollut Suomen sisäinen valtataistelu ulkopoliittisesta linjasta ja ketkä ovat olleet tämän valtataistelun osapuolia? Mikä rooli sosialidemokraateilla oli, kun Suomen puolueettomuuspolitiikka korvattiin aktiivisella rauhanpolitiikalla? Mitä suomettuminen oli, milloin se tapahtui? Miksi neuvostomyönteisyys oli tunnusomaisempaa vasemmistopoliitikoille? Millä keinoin sekä sosialidemokraatit että KBG tavoittelivat sosialistista Suomea? Studiossa vieraana valtiotieteiden tohtori, professori Vytautas Magnus -yliopistossa ja entinen suurlähettiläs Alpo Rusi. Jakso on nauhoitettu 4.4.2022.

Jack Barsky was born in East Germany and grew up as big believer in communism and that the Soviet Union was fighting the good fight against the United States. So much so in fact, that he volunteered to work as a spy who lived a double life in America all the while sending information back to his handlers in Moscow only to be won over in the end by the American way of life. This is his story. (commercial at 16:17)To contact me:bobbycapucci@protonmail.comsource:https://news.yahoo.com/jack-barsky-russian-spy-apos-060829584.html

Elon Musk now on the board of Twitter, does that mean he will put an end to election interference? Herschel Walker, US Senate Candidate believes he is being suppressed during this primary season. KBG brings out political pedos with her bend toward leniency toward child rapists. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Stig Fredrikson är en tungviktare inom journalistkåren som bl.a. varit utrikeskorrespondent i Moskva och skrivit boken "Ryssland utan Putin". Vi pratar med Stig om Vladimir Putins uppväxt, bakgrund, hur han tog sig till makten och vem han är idag. Vad är ett Ryssland utan Putin? Hur har hans bakgrund i KBG påverkat honom? Varför anser han att väst har vänt Ryssland ryggen? Och är han en galning, som vissa vill få det att framstå som?

I got a nerve to dig deeper on fears, KBG, Russian Mafia and so much more with one of the most intriguing minds and experienced Ph.D.'s beyond academia, author of over eight great books, exceptional storyteller, trainer, and human, Joe Serio.Buckle up, Champions! This is one of the most fascinating life stories you simply can't miss.To get a signed copy of Joe's new book, go to vodkahookers.com or to learn more about his services at glt.com

I got a nerve to dig deeper on fears, KBG, Russian Mafia and so much more with one of the most intriguing minds and experienced Ph.D.'s beyond academia, author of over eight great books, exceptional storyteller, trainer, and human, Joe Serio. Buckle up, Champions! This is one of the most fascinating life stories you simply can't miss. To get a signed copy of Joe's new book, go to vodkahookers.com or to learn more about his services at glt.com

Nicolas Fernandez is a student at Florida International University where he is studying Dietetics. He is also a nutrition coach who is currently training to compete in the sport of CrossFit.Find him at https://www.instagram.com/nicolasfernanddezz/***TIMESTAMPS***0:00 - Intro4:30 - CrossFit training and becoming obsessed with the sport; nutrition and Nicolas background and struggles that lead him to make fitness and eating healthy his main goals; no more excuses and finding discipline in your life24:45 - Mat Fraser, Noah Ohlsen and their different training techniques; one chose to train alone the other with others; SUSTAINABILITY; definitions of success37:50 - Freedom in the US; observing the many counter that have fallen to Communist control and the current fear and worries with current generation and society; issues with Socialism and Communism52:45 - KBG agent clip here's the full version on YouTube, https://www.youtube.com/watch?v=bX3EZCVj2XA, full clip has been removed by YouTube; Reflecting on KGB agent clip predicting the collapse of America; Pitfalls of ideology and where it can lead to disaster; Victimhood mentality (healthcare and education); Quarantine time and the REAL issues not being discussed 1:01:20 - Nutrition & Sleep, the issue is people under-eating and having no conception of what is a healthy diet and how macros is not a long term solution; Alessi's theory on where all these new diseases are coming from (outside of genetics)1:11:00 - School and finding your career; the interesting observation of watching students doing school just to complete it and not taking the time to figure out what you want to do (I am victim of this; competing in CrossFit and training and the genetics that play a role in the sport1:29:31 - Outro~YouTube EPISODES:https://www.youtube.com/channel/UCyLKzv5fKxGmVQg3cMJJzyQ/videos~Song provided by: Ayush Garg

Kai Schimmelfeder beleuchtet die MBG Fördermittelberatung für das Wachstum von Unternehmen. feder consulting liefert Fördermittel, Fördergelder und Zuschüsse für Unternehmen

Lauren Tallman lived in six cities, in four countries.She was arrested in New York for protesting against an intolerable situation.She rode camels in the desert.Lauren acted as a go-between with a Russian anti-KBG agent and an Israeli counterpart.She speaks three languages fluently and knows enough of a fourth to get her in trouble.Lauren Tallman is an author.She wouldn't change a single thing that happened in her life. Currently a resident of Las Vegas, author Lauren Tallman has an international background. Born in Lithuania, came to America via Italy, resided in Israel for over thirty years, and landed in Las Vegas in 2006.For several years, Lauren was a member of a writing group in Israel where she received constructive critique and advice from international writers.She is a member of the Henderson Writers Group since 2009.Lauren founded the Erotic Writers Group of Las Vegas in 2014. She still has time to lecture about keeping affairs secret, while speaking on podcasts. Her book How To Have An Affair And Not Get Caught went worldwide and relaunched in 2020. Lauren unleashed the erotic Harem of the Dragon in 2020 which received vast praiseTaste the Kiss Feel the Fire, Lauren's erotica group's anthology, was released in October 2021.She is presently working on the upcoming erotic novel The Erotic Tales of Renni. You can check Lauren out on the web at www.laurentallman.com

Housekeeping: Are you a Reel level Patron? Check your messages for a shirt size from JPink! Headlines: Mosaic Shares Falter after Vale's $1.26B Mosaic Stock Sale  $200/hour offered for snowplow drivers amid shortage  GIE+EXPO attendance over its 2019 showing  Burns: Dubuque fertilizer company to pay $270K after spill that killed fish, mussels  Senators Seek Support of Bills Silencing Gas-powered Lawn Equipment  Tariffs Lead to Phosphate Shortage  Returns: An Interview with the editors of Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts  Modern chemical pesticides are needed more than ever to fight rising food prices, climate change and world hunger  Teenager struggles in job interviews, starts own mowing business  Mailbag: Important cultural considerations for KBG over TTTF? Help identifying weeds Remediating a bumpy lawn Special Thanks to Our Co-Producers: 6r33k633k Johnny Fescue Benjamin Mossing Trucka Trav Lonegoose Brennen man0matrix Michael Brantley Jesse Bousquet Jr John Wilbanks Outsidefire Barthoda Deadphishy Tifway Lawn Nate Kressly Alex Smith GuardWellDFW Timms Tdougie Fresh William Wood

In this episode, we are honored to speak with academic, sci-fi, and dark fantasy writer, Elana Gomel.Elana Gomel has taught and researched English literature and cultural studies at Tel-Aviv University, Princeton, Stanford, Venice International University, and the University of Hong Kong. She is currently dividing her time between California and Tel-Aviv. Elana is the author of five academic books and numerous peer-reviewed articles on posthumanism, science fiction, Victorian literature, and serial killers. Her fantasy, horror, and science fiction stories have appeared in numerous publications, including Apex Magazine, New Horizons, and The Fantasist. Elana's stories have been featured in several award-winning anthologies, including Zion's Fiction, Apex Book of World Science Fiction, and People of the Book.Elana's first novel A Tale of Three Cities was published in 2013, followed by her novella Dreaming in the Dark in 2017. In 2018 she published her first collection of short stories Un/home and her dark fantasy novel The Hungry Ones. In 2019 she published her sci-fi hybrid horror novel The Cryptids. Most recently, she signed a contract with Vernacular Books for her novel Nightwood. When she is not busy writing or teaching, Elana is on a plane headed somewhere far away and exotic in search of new monsters. We talk to Elana about her soon-to-be-released tribute to California, Nightwood from Vernacular Books. Elana shares her thoughts on the intersection, or not, of her academic work and her creative works.  She writes and publishes frequently and we wanted to know how she manages her time .Elana explains her world-driven writing. We were thrilled to hear that the monsters are her favorites and the surprising place that the inspiration for them comes. Elana won the 2020 Gravity Award for “Where the Streets Have No Name”, we asked her about the winning story and about the award. She shares a bit about her process for writing a piece and how long it takes her. In addition to Nightwood, Elana's novella Little Sister is coming out on October 15 from Crystal Lake Publishing. Elana shares her childhood memories of the USSR, KBG visits, the strong women in her family, and the forgotten history that inspired the story.  We chatted about her piece The Niddah as her response to the pandemic and what we can learn from it.Find out more about Elana and her work here:https://www.citiesoflightanddarkness.comand here:https://www.amazon.com/Elana-GomelFind some of her works here:The Niddah from Apex Magazinehttps://apex-magazine.com/the-niddah/Tanri from Of Metal and Magichttps://ofmetalandmagicpublishing.wordpress.com/tanri/Pareidolia from Frost Zone Zinehttps://frostzonezi**When you purchase through links on our site, we may earn an affiliate commission.*Disclaimer: Reference to any specific product or entity does not constitute an endorsement or recommendation by the Podcasters. The views expressed by guests are their own and their appearance on the podcast does not imply an endorsement of them or any entity they represent. Views and opinions expressed by guests do not necessarily reflect the views and opinions of the podcasters.

It's The Daylights... The Living Daylights! With a US release date of the 31st of July, 1987, this James Bond movie was the introduction of Timothy Dalton in the lead role. It's a slightly more grounded adventure compared to the previous era of the franchise but still has all the classic one-liners, action set-pieces, and green flags. We're joined by podcaster Rhys Parton to check it out! Join the Bad Porridge Club on Patreon for TWO bonus episodes each month! https://www.patreon.com/oldiebutagoodiepod Follow Rhys Parton! Twitter: https://twitter.com/rhysparton Instagram: https://www.instagram.com/rhyspartonphotography Photography: https://www.instagram.com/rhyspartonphotography Youtube: https://www.youtube.com/channel/UCuM9yepgLbYg8_ct8Go8uJQ Follow the show! Instagram: https://www.instagram.com/oldiebutagoodiepod/  Facebook: https://fb.me/oldiebutagoodiepod Youtube: https://www.youtube.com/channel/UCjfdXHxK_rIUsOEoFSx-hGA  Podcast Platforms: https://linktr.ee/oldiebutagoodiepod  Got feedback? Send us an email at oldiebutagoodiepod@gmail.com Follow the hosts! Sandro Falce - Instagram: https://www.instagram.com/sandrofalce/ - Twitter: https://twitter.com/sandrofalce - Letterboxd: https://letterboxd.com/SandroFalce/ - Nerd-Out Podcast: https://anchor.fm/nerd-out-podcast  Zach Adams - Instagram: https://www.instagram.com/zach4dams/ Donations: https://paypal.me/oldiebutagoodiepod Please do not feel like you have to contribute anything but any donations are greatly appreciated! See omnystudio.com/listener for privacy information.

Szia, Kedves Hallgató! A KBG podcast első évada lassan a végéhez közeledik. Arra gondoltam, hogy kikérem a te véleményedet is, hogy kit hallgatnál.  Szóval, ha van olyan gyergyói ember akit, érdekesnek, produktívnak, inspirálónak találsz, és szívesen megismertetnéd másokkal írd meg nekem Instagramon, vagy Facebookon a KBG podcast oldalain, s én majd jól kifaggatom.    Az Instagramon és a Facebookon is létrehoztunk egy ide vágó bejegyzést és ott akár hozzászólásban is meg írhatod az ajánlásodat. Várom az ötleteidet! Addig is ne feledd: Kösz, ha hallgatsz!   Google Podcasts: http://bit.ly/3aLlwV3 Apple Podcasts: http://apple.co/3aCRHWp Spotify: http://spoti.fi/3dzwpLf Podbean: https://bit.ly/3qJBYdF Youtube: http://bit.ly/3v2gADb Facebook: http://bit.ly/3dzBwel Instagram: https://bit.ly/30nQHzs  

On today's show my co-host is Brandon from the Turf Culture YouTube channel (formerly Bush League Lawns). Brandon is one my fellow St. Louis lawn care nuts. Just like me he's just your average joe that enjoys lawn care as a hobby and outlet from the day to day grind of his full time job. Last year he did a full renovation on his front lawn. He killed off his TTTF fescue and went all in with a KBG lawn that he is reel mowing. This is next level lawn care and I have no doubt he's going to be learning a lot along the way and sharing this knowledge on his YouTube channel. It's great to have another midwest lawn care nut from the community on the show. It was fun hanging out with him and everyone in the chat! So wherever you are, grab your favorite beverage, get comfortable, and sit back and enjoy some laughs, tips, tricks, and hopefully some great stories! It was such a great show and I hope you all enjoy it! Feel free to join us LIVE when we record these shows on my YouTube channel every Friday night at 8:30pm CST. We always enjoy interacting with our audience in the chat as it brings an additional aspect of spontaneity to the show's conversation. Check out, Subscribe, and Follow us on Social Media: The Lawn Guardian: YouTube: https://www.youtube.com/c/thelawnguardian Instagram: https://www.instagram.com/thelawnguardian/?hl=en Twitter: https://twitter.com/LawnGuardian Facebook: https://www.facebook.com/TheLawnGuardian Brandon from Turf Culture: YouTube: https://www.youtube.com/c/BushLeagueLawns Instagram: https://www.instagram.com/turf_culture/?hl=en

On today's show my co-host is George from the Princess Cut Lawn Care YouTube channel. George started his lawn care YouTube journey last year and has a great channel that has grown a lot in just one year. He's a DIYer that has gone all in with reel mowing and creates awesome content for his audience on how he maintains that lush shortcut KBG in the Chicagoland area! It was fun hanging out with him and everyone in the chat! So wherever you are, grab your favorite beverage, get comfortable, and sit back and enjoy some laughs, tips, tricks, and hopefully some great stories! It was such a great show and I hope you all enjoy it! Feel free to join us LIVE when we record these shows on my YouTube channel every Friday night at 8:30pm CST. We always enjoy interacting with our audience in the chat as it brings an additional aspect of spontaneity to the show's conversation. Check out, Subscribe, and Follow us on Social Media: The Lawn Guardian: YouTube: https://www.youtube.com/c/thelawnguardian Instagram: https://www.instagram.com/thelawnguardian/?hl=en Twitter: https://twitter.com/LawnGuardian Facebook: https://www.facebook.com/TheLawnGuardian George from Princess Cut Lawn Care: YouTube: https://www.youtube.com/channel/UCq0p8LiC9_xsSi_3qrcvm1w Instagram: https://www.instagram.com/princesscutlawn/?hl=en

Blame may be clear after a car accident, but multiple parties could be partially at fault for the end result. On this episode, KBG attorneys Ted Kennett and Wes Addington discuss how partially at fault determinations are made and the impacts on personal injury claims and compensation.

Welcome to the Average Joe Lawn Care Show! In this second episode Jimmy Lewis joins me as my co-host and we dive into some good ol lawn care talk from a DIYer perspective. Jimmy Lewis is a lawn care YouTuber out in Utah where he has a beautiful KBG lawn. He's one of the few DIYers in own community that reel and rotary mows different sections of his lawn. I hope you all enjoy this show! Feel free to join us LIVE when we record these shows on my YouTube channel every Friday night at 8:30pm CST. We always enjoy interacting with our audience in the chat as it brings an additional aspect of spontaneity to the show's conversation. Check out, Subscribe, and Follow us on Social Media: The Lawn Guardian: YouTube: https://www.youtube.com/c/thelawnguardian Instagram: https://www.instagram.com/thelawnguardian/?hl=en Twitter: https://twitter.com/LawnGuardian Facebook: https://www.facebook.com/TheLawnGuardian Jimmy Lewis: YouTube: https://www.youtube.com/channel/UCqo1Ck8zVhI_TjAEP5s0LxA Instagram: https://www.instagram.com/jimmylewis_1/?hl=en

We’re talking fall clean up - not of your car, or your love life - of your garden. Christy is digging holes and Edith accidentally drops gutter gunk on her daughter.  Along the way we touch on how giant hidden zucchinis are like the KBG, and how rosemary heads for the portal every March.  A letter from Albuquerque teaches us about an exploding caterpillar, the importance of a back up caterpillar, and potato traps for pillbugs. Christy is in search of thrilling pumpkin stories. A first for UDT: a fashion show that previews what gardeners will be wearing next year. Plus all your questions about how and when to clean up and prepare your garden for a successful garden next spring.Visit our website for pix, more info and Upside Down DictionaryClick here to write to us! We would love to  hear your garden stories & Q's!

KBG defector? CIA plant? Bircher stooge? Whistleblower who tried to warn us of Russian subversive activities? In light of KGB defector Yuri Bezmenov's recent pop culture emergence we look into this mysterious figure who has played such a big part in the shadowy side of many peoples' conception of The Cold War.

Mais uma semana, mais arrepios.

Karena kemarin udah tau tentang KBG, di part3 kali ini kita bakal bahas tentang Detail nya. Kira kira apa aja sih Dampak dari KBG ?

KBG ? Apa itu ? Kalian dah pada tau belom kekerasan berbasis gender itu apa ? Kalo banyak yang belom tau, skuy langsung di dengerin Podcast Special Part nya hehe.

To help regional nonprofits during a time of immense need, KBG created the 10 for 10 initiative. Each day, a KBG attorney chose a local organization to receive $1,000 from KBG’s Community Fund. (KBG actually has 11 attorneys, so while we called it the “10 for 10,” we took it to 11. A total of $11,000 was donated.) In this episode, personal injury and wrongful death attorney Brian Strong discusses his choice in donating to Downtown Inc. He’s joined by a special guest, Downtown Inc Director Elaine Bonneau.

Kekerasan Berbasis Gender (KBG) adalah salah satu isu yang ada kehidupan ini. Sadar atau tidak, ini tuh bisa berdampak besar pada kesehatan seseorang. Setelah melihat besarnya impact dari KBG ini kepada kesehatan, itu sebabnya podcast ini dibuat. Isu ini perlu diangkat lebih lagi, supaya banyak yang lebih aware soal ini. Yang sharing di podcast ini adalah Isabella Veronica, MA (@isabellaveronicaa) yang adalah Regional Leader, Girl Up Indonesia (@girlupindonesia) United Nations Foundation. Tamat dari George Washington University dengan gelar master International Affairs majoring in International Law & Organizations (M.A.). Isabella sangat-sangat passionate sharing mengenai isu Kekerasan Berbasis Gender (KBG). You will feel it ketika denger podcast ini! Apa saja sih impact dari KBG ini kepada kesehatan seseorang? Temukan jawabannya di podcast ini! Enjoy listening!

KBG workers’ comp lawyers Dean Dominick and Drew Gannon reflect on the changes of the PA Workers’ Compensation Act since it was enacted in 1915, and how the Act still pertains to employees and employers today.

We get this question a lot so, so here's a mini episode with my thoughts.In Utah (cool season grass) I recommend seeding in the fall when there are a lot fewer variables to work around and the weather is on your side.

Kylie Zehnder talks about the day she learned her daughter, Alaina, had KBG syndrome.

This episode is a life and podcast update for my wonderful listeners. I will be giving y'all the tea on what I have been working on this summer, who I am dating, as well as some personal life updates. I know I have been away this summer but I want y'all to know I have been working on providing y'all with better and more accessible content. As always follow me on IG at the_KBG_podcast_ for more info! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/kbg-podcast/support

A Dictator, a Dictator and a Dick meet at the DMZ for a ground breaking ceremony for the latest luxury hotel with it's very own torture spa with other great amenities like the waterboard massage table, drowning pool and KBG cocktail (make sure you ask for the Uppity Journalist... Vlad make that one himself).

An update on my life and the future of KBG!!!! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/kbg-podcast/support

Hey Everyone , Thank you so much for listening to my first episode of KBG! I know its a tad short but its just some foreplay to get us ready for the main event. I would love to hear your feed back so please comment like and follow us on instagram. Thank you all again for your support ! Love P --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/kbg-podcast/support

Idealisten! The Honeypot! Den grådige! Det handler om spioner. Nærmere bestemt amerikanske KBG-spioner. Vi taler om spionen, der gav Stalin planerne til atombomben, spionen, der forførte den nazistiske ledelse og spionen, der næsten blev vicepræsident. Marie skal finde en æggende, men dækkende roe til Miss Lolland-Falster og Katrine taler om glæden ved flere kildesæt. 

Choose Your Own AdventureBook 6 - Your Code Name is Jonahby Edward Packardillustrated by Paul Grangerread by JillJeromy and Jason face hard decisions regarding the "KBG," whether or not to get into a car, and how to properly get to shore. They also get a Mark 3K harpoon gun and have a whale of a time using it!Support Choose Your Own Adventure and Edward Packard:https://www.cyoa.comhttps://www.edwardpackard.comTwitterFacebookYoutubeiTunesStitcherGoogle PlayVisit us at: https://www.stupendousaurusrex.comContact us at: stupendousaurusrex@gmail.comStock media provided by timbeek/Pond5(We have your book, David Stoltz, and no, you cannot have it back!)

In this episode I talk with Eric Dezenhall, CEO of Dezenhall Resources, a nationally recognized high-stakes communications firm representing corporations and institutions facing controversy. Eric is the author of nine books, including his most recent, Best of Enemies, co-authored with Guss Russo. Listen and journey back to a time of loss, love and learning for Eric and hear about the unlikely connection between about a CIA officer, KGB agent, and of all people, Robert DeNiro, who helped the KBG agent stay alive in a Russian prison. Eric's new book, Best of Enemies: The Last Great Spy Story of the Cold War cab be ordered today on Amazon.com. Wanna be a guest? Visit my website or DM me on Instagram or my Breathe with Eileen Fein Facebook page to nominate yourself or someone you know who has a moving story of connection to be on the podcast! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Jesus Christ is the reason for the season. Lets celebrate our Savior and Lord Jesus The Son of the living God. We got fresh music by KBG, Mag44, Nolly, YangDove, … The post Christmas Special Edition 2017 appeared first on DJ Octave.

Hard to believe it's 20 years this coming week since Cavan last won the Anglo-Celt cup. To remember that great occasion Damien Donohoe caught up with the full back from that team Ciaran Brady at KBG accountants in Cavan ahead of Counting on you on July 22nd.

With the deadline for the exciting Counting On You fundraiser, in aid of Pieta House, fast approaching, on this special episode we caught up with some of footballing staff at KBG to talk about this novel charity free-taking event.

Hoy nos visita "Numan" del grupo electro "KBG" donde nos acompaña Celes Bernáldez del podcast "CafeGeek". Promocionamos el nuevo disco de KBG donde nos cuenta algunas anécdotas y nos pone al día sobre los nuevos trabajos. Además nos informa de como trabaja desde un entorno Apple para la creación de los temas musicales. Abarcamos el mundo de la música digital donde Apple Music da unos benefícios pésimos a los creadores de contenidos. Explicamos como Apple pone las herramientas para ayudarte desde el salón de casa a crear, producir, promocionar y lanzar vuestros temas musicales con una inversión de "CERO" gracias a iTunes Connect. Sorteamos de nuevo una funda para iPhone gracias a Fundilandia (ESCUCHA EL PODCAST PARA VER SI ERES EL GANADOR) y si lo eres ponte en contacto con @Fundilandia. Seguimos hablando de la leyenda de "un MAC no es para jugar" donde descubrimos que un PC tampoco está diseñado para jugar (tienen razón y nos detallan sus posturas) Como siempre agradeceros las reseñas y cinco estrellas en iTunes, los comentarios en el directo y en iVoox. Podéis encontrados en las redes sociales como "ApleDecir" y como siempre, nos vemos en 7 días a las 22:22h. ¡Saludos!

bit.ly/impreshsesh the wildest shit out there this month from tree frogs to humans impression session is a monthly (roughly) series of mixes of music that leaves an impression created by @umrumusic + friends _____________________ tracks: Zero Tep - Kermit on the Weekends w/ Noer the Boy Mike Gao - Clangdashian (feat. Pidjeon) Thook - 40 on dust Die Antwoord - Cookie Thumper (umru flip) Chindamo + Stone - Tesla KRNE + Quix - Monuments Future - Sh!t (Chahine Flip) mr. carmack - solutions ft. Donnis Sam Gellaitry - long distance Y4NN - WOOD$ ADUSTIO - Redline Losi - Sleep (Never) mr. carmack - womp bonzai - KBG _____________________ discover impression session: bit.ly/impreshsesh tags by the bro @hittown, lyza jarvis, others cover photo by umru ____________ UMRU―05

Listen to the Healthy Voyager Radio right here!! Featuring Vance Lemkhul of Vegcast and the Bizarro King, Dan Piraro: Healthy Voyager RadioNext week we chat with Eat Cleaner's Mareya Ibrahim and raw chef, Bryan Au!!

Most primary production of lakes and oceans occurs in the well-mixed surface layer that is subject to strong seasonal and geographical variation. With increasing mixed surface layer depth average light supply and specific nutrient supply decrease and so do light-dependent production rates and depth-dependent sinking loss rates of phytoplankton. Changes in mixing depth are expected to have important consequences for the dynamics of phytoplankton biomass, algal nutrient stoichiometry, light availability and nutrient retention in the mixed layer. Light absorption by enhanced concentrations of abiotic substances (humic substances, clay particles) furthermore negatively affects light availability and production. I tested the predictions of a dynamical “closed system” model concerning the effects of mixing depth and background turbidity (Kbg) on phytoplankton biomass, light climate and nutrients in a field enclosure experiment. The natural phytoplankton community was exposed to high and low background turbidity along a gradient of mixing depth. For sinking algae, the model predicts that phytoplankton biomass should be most strongly limited by sedimentation losses in shallow mixed layers, by mineral nutrients at intermediate mixing depths and by a lack of light in deep mixed layers. As predicted, phytoplankton volumetric and areal biomasses showed a unimodal relationship to mixing depth and were negatively affected by background attenuation. With increasing Kbg the biomass peak shifted towards shallower mixing depth. The concentrations of dissolved and total nutrients were positively affected by increasing mixing depth but only marginally related to Kbg most likely due to a variable carbon to phosphorus cell quota. For thermally stratified lakes I derived the following predictions from a dynamical “open system” model which includes variable algal cell quota: within a realistic mixing depth range (3-12m) light availability, phytoplankton density, and the carbon:phosphorus ratio of algal biomass should all be negatively related to mixing depth, while algal standing stock should be unimodally related, and total and dissolved nutrients be horizontally or positively related to mixing depth. All these prediction were in qualitatively good agreement with data from 65 central European lakes sampled during summer stratification. Notably, I observed the predicted negative relationship between phytoplankton density and mixing depth in spite of the rather limited range of mixing depths typical for medium sized temperate lakes. Furthermore, I found a strong negative relationship among zooplankton biomass and mixing depth. In a comprehensive comparative lake study of 40 northern German lakes, I sampled the surface mixed layers for a set of variables and focused on the taxonomic composition of phytoplankton and the relationships of taxonomic classes to environmental variables. I used high performance liquid chromatography to analyse the phytoplankton samples for 13 photosynthetic pigments and calculated the contributions of seven algal classes with distinct pigment signatures to total chlorophyll a using CHEMTAX, a matrix factorisation program. In multiple regression analyses, I examined the relationships of phytoplankton biomass and composition to total nitrogen (TN), total phosphorus (TP), total silica (TSi), mixing depth, water temperature, and zooplankton biomass. Total Chl-a was positively related to TN and TP and unimodally related to mixing depth. TN was the factor most strongly related to the biomasses of single taxa. I found positive relationships of chrysophytes, chlorophytes, cryptophytes, and euglenophytes to TN, and of diatoms and chrysophytes to TSi. Diatoms were negatively related to TN. Cryptophytes and chlorophytes were negatively and cyanobacteria positively related to zooplankton. Finally, the relative biomasses of chrysophytes and cryptophytes were negatively related to mixing depth. Most results were consistent with theoretical expectations. Some relationships may, however, have been masked by strong cross-correlations among several environmental variables.