POPULARITY
Drs. Kittleson and Ghafourian discuss how to accurately diagnose ATTR-CM, emphasizing that the first step must always be a complete monoclonal protein screen to exclude AL amyloidosis before interpreting a PYP scan. They highlight common pitfalls with PYP imaging; the supportive (but not definitive) role of cardiac MRI; the need for routine TTR genotyping after diagnosis; and the importance of recognizing noncardiac clues to identify patients early enough to benefit from disease‑modifying therapies.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NUP865. CME/NCPD/CPE/AAPA/IPCE credit will be available until July 12, 2027.All-in for Transthyretin Amyloidosis: Refining Team-Based Approaches to Diagnosis, Treatment, and Lifesaving Patient-Centered Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Alnylam Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NUP865. CME/NCPD/CPE/AAPA/IPCE credit will be available until July 12, 2027.All-in for Transthyretin Amyloidosis: Refining Team-Based Approaches to Diagnosis, Treatment, and Lifesaving Patient-Centered Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Alnylam Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.
PeerView Neuroscience & Psychiatry CME/CNE/CPE Audio Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NUP865. CME/NCPD/CPE/AAPA/IPCE credit will be available until July 12, 2027.All-in for Transthyretin Amyloidosis: Refining Team-Based Approaches to Diagnosis, Treatment, and Lifesaving Patient-Centered Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Alnylam Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.
PeerView Neuroscience & Psychiatry CME/CNE/CPE Video Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NUP865. CME/NCPD/CPE/AAPA/IPCE credit will be available until July 12, 2027.All-in for Transthyretin Amyloidosis: Refining Team-Based Approaches to Diagnosis, Treatment, and Lifesaving Patient-Centered Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Alnylam Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NUP865. CME/NCPD/CPE/AAPA/IPCE credit will be available until July 12, 2027.All-in for Transthyretin Amyloidosis: Refining Team-Based Approaches to Diagnosis, Treatment, and Lifesaving Patient-Centered Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Alnylam Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NUP865. CME/NCPD/CPE/AAPA/IPCE credit will be available until July 12, 2027.All-in for Transthyretin Amyloidosis: Refining Team-Based Approaches to Diagnosis, Treatment, and Lifesaving Patient-Centered Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Alnylam Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.
What does grief need from us - time, understanding, or something else entirely?In this episode, I'm joined by Kyle Kittleson, host at MedCircle, to explore what it means to live alongside grief rather than trying to fix or outpace it. We talk about how loss shapes the way we listen, why grief resists timelines, and what thousands of conversations with mental health experts have revealed about what actually helps. This conversation offers permission to slow down, trust your own rhythm, and rethink what healing can look like.Links + Resources from this episode:Kyle Kittleson at MedCircle: https://medcircle.comJoin the Restorative Grief Community: https://www.facebook.com/groups/rests Become a Patron: https://www.patreon.com/mandycapehartSubscribe to the Restorative Grief Newsletter: https://www.mandycapehart.com/subscribe Work with Mandy: https://www.mandycapehart.com/coaching
In this episode of Parallax, Dr Ankur Kalra is joined by Dr Michelle Kittleson, Professor of Medicine and Advanced Heart Failure Cardiologist at Cedars-Sinai Medical Center, for a clinically rich breakdown of her standout trial picks from the 2026 ACC Annual Scientific Sessions. Dr Kittleson brings her characteristic precision to four landmark studies spanning heart failure and atrial fibrillation. She unpacks the SPIRIT HF trial — a negative study of spironolactone in HFpEF that, she argues, does not consign the drug to the shelf — and explains why its high discontinuation rate and pandemic-era disruptions complicate the headline result. For clinicians managing cost-conscious patients, her take on spironolactone as a practical alternative to finerenone is a perspective worth hearing. The conversation turns to the CADENCE trial, a Phase 2 study of sotatercept in Group 2 pulmonary hypertension secondary to HFpEF — a phenotype Dr Kittleson treats with particular caution given the risks of misdirected pulmonary vasodilator therapy. She offers measured optimism about what these early results might mean for future treatment of HFpEF-related lung remodelling. Dr Kalra and Dr Kittleson also enter the ongoing debate around left atrial appendage closure, weighing the contrasting conclusions of the CLOSURE AF and CHAMPION AF trials against each other — and against a shared conviction that anticoagulation remains the standard of care for the vast majority of patients with atrial fibrillation. Finally, they examine the STEMI Door to Unload trial, a cautionary study in indication creep: the microaxial flow pump that proves life-saving in cardiogenic shock offered no infarct-size benefit in haemodynamically stable STEMI patients — and came with a meaningful increase in bleeding and vascular complications. Dr Kittleson also shares her stepwise outpatient algorithm for a new HFpEF diagnosis, from ruling out mimics such as cardiac amyloidosis to sequencing SGLT2 inhibitors, MRAs, GLP-1 agonists, and ARNIs based on individual patient profile. The episode closes with a discussion of her new column for NEJM Voices, where she writes on the art of medicine. Questions and comments can be sent to podcast@radcliffe-group.com and may be answered by Ankur in the next episode. Host: @AnkurKalraMD and produced by: @RadcliffeCardio Parallax is Ranked in the Top 100 Health Science Podcasts (#48) by Million Podcasts.
In this episode I talk with fellow grief expert Kyle Kittleson. After the death of his mother, Kyle found that talking about his loss to be among the few things that was truly helpful, and began a new career path that put him directly in touch with other people dealing with trauma. His work with MedCircle has proven that hope and help are always available, and that finding ways to work on our own mental health is more accessable than ever. We talk about how helpful it can be just to be in service of someone elses journey, and how much it matters that we keep telling our stories. Check out Medcircle and all that Kyle does at https://medcircle.com/ and on IG @MedCircleOfficial Check out Kyle's youtube BahBahBlast! https://www.youtube.com/@babablast
In today's episode, we break down the latest developments in the escalating Iran situation, including new reporting on a potential ceasefire window, B-52 movements, and what Trump's strategy could mean moving forward. Is this another example of “Art of the Deal” in action—or something bigger?We also cover the political commentary around the release of journalist Shelly Kittleson, reactions from Iranian officials, and the growing tension both overseas and here at home. Back in the U.S., the political chaos continues. From calls for impeachment to media figures and political commentators taking shots at Trump, the divide couldn't be clearer. We highlight moments from CNN panels, George Conway's TDS comments, and the broader narrative shaping the media landscape.Meanwhile, a resurfaced speech from Gavin Newsom's wife is going viral—and not for the reasons they hoped. Her comments on prison, masculinity, and free speech are sparking major backlash, adding fuel to the already heated culture war.Plus reactions to viral moments from Tucker Carlson, Theo Von, and Stephen Colbert.SUPPORT OUR SPONSORS TO SUPPORT OUR SHOW!Achieve better sleep this spring with REM Sleep from Healthycell. Go tohttps://Healthycell.com/Chicks with code CHICKS20—no pile of pills needed.CowGuys—head to https://CowGuys.shop/Chicks to getyour bottle and get a travel-sized mini balm for free. No code needed. That's 3-4 months ofmoisturizer for $34.DeleteMe helps you take control of your data and protect your privacy—get 20% off athttps://JoinDeleteMe.com/Chicks with code CHICKS.Subscribe and stay tuned for new episodes every weekday!Follow us here for more daily clips, updates, and commentary:YoutubeFacebookInstagramTikTokXLocalsMore InfoWebsite
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10. The Kidnapping of Shelley Kittleson in Baghdad Guest: Bridget Tumi and Bill Roggio Summary:Kata'ib Hezbollah has abducted an American journalist in Baghdad to use as leverage for prisoner exchanges. Guests discuss the militia's deep integrationinto the Iraqi government and the risk of hostages being moved to Iran.,, (10)1873 SHAH AND PRINCE OF WALES (LATER KING GEORGE)
AP Washington correspondent Sagar Meghani reports an Iraqi official reports an American freelance journalist kidnapped in Baghdad last week has been freed.
We learn about a journalist from Wisconsin who was abducted in Iraq last week. We look at the use of NDAs by local towns for data center deals. Wisconsin's most popular state park is getting bigger.
Last week, journalist Shelly Kittleson, who grew up in Wisconsin, was kidnapped while reporting in Iraq.
(3.25.2026-4.1.2026) Foolin' around. Tune in. #applepodcasts #spotifypodcasts #youtube #amazon #patreonpatreon.com/isaiahnews
On "Forbes Newsroom," geopolitical analyst Hollie McKay, a former war correspondent who has reported from Iraq, discussed the kidnapping of U.S. journalist Shelly Kittleson in Iraq, for whom the State Department says it working to secure the release. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode of the MyHeart.net podcast, Dr. Alain Bouchard discusses the interplay between Heart Failure with Preserved Ejection Fraction, or HFpEF, and obesity with Dr. Michelle Kittleson, Director of Heart Failure Research at the Smidt Heart Institute at Cedars-Sinai.Learn more about the diagnosis, challenges, and management of this condition by exploring our article, Managing Obesity in Heart Failure with Preserved Ejection Fraction (HFpEF).About the TeamDr. Alain Bouchard is a clinical cardiologist at Cardiology Specialists of Birmingham, AL. He is a native of Quebec, Canada and trained in Internal Medicine at McGill University in Montreal. He continued as a Research Fellow at the Montreal Heart Institute. He did a clinical cardiology fellowship at the University of California in San Francisco. He joined the faculty at the University of Alabama Birmingham from 1986 to 1990. He worked at CardiologyPC and Baptist Medical Center at Princeton from 1990-2019. He is now part of the Cardiology Specialists of Birmingham at UAB Medicine.Dr. Philip Johnson is originally from Selma, AL. Philip began his studies at Vanderbilt University in Nashville, TN, where he double majored in Biomedical and Electrical Engineering. After a year in the “real world” working for his father as a machine design engineer, he went to graduate school at UAB in Birmingham, AL, where he completed a Masters and PhD in Biomedical Engineering before becoming a research assistant professor in Biomedical Engineering. After a short stint in academics, he continued his education at UAB in Medical School, Internal Medicine Residency, and is currently a cardiology fellow in training with a special interest in cardiac electrophysiology.Medical DisclaimerThe contents of the MyHeart.net podcast, including as textual content, graphical content, images, and any other content contained in the Podcast (“Content”) are purely for informational purposes. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or heard on the Podcast!If you think you may have a medical emergency, call your doctor or 911 immediately. MyHeart.net does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Podcast. Reliance on any information provided by MyHeart.net, MyHeart.net employees, others appearing on the Podcast at the invitation of MyHeart.net, or other visitors to the Podcast is solely at your own risk.The Podcast and the Content are provided on an “as is” basis.
Kyle Kittleson is a YouTube host and a mental health and animal advocate. He shares his experience with losing his mother as a child, how it affects his adult relationships, and the importance of building empathy and resilience, particularly in children. More about KyleLook for his videos on MedCircle.com and BabaBlast.comThis episode is sponsored Quince. Go to www.Quince.com/mental for free shipping on your order and 365-day returns. Now available in Canada, too.This episode is sponsored by AlmaVisit helloalma.com/happyhour to schedule a free therapy consultation today.If you're interested in seeing or buying the furniture that Paul designs and makes follow his IG @ShapedFurniture or visit the website www.shapedfurniture.comWAYS TO HELP THE MIHH PODCASTSubscribe via Apple Podcasts (or whatever player you use). It costs nothing. It's extremely helpful to have your subscription set to download all episodes automatically. https://itunes.apple.com/us/podcast/mental-illness-happy-hour/id427377900?mt=2Spread the word via social media. It costs nothing.Our website is www.mentalpod.com our FB is www.Facebook.com/mentalpod and our Twitter and Instagram are both @Mentalpod Become a much-needed Patreon monthly-donor (with occasional rewards) for as little as $1/month at www.Patreon.com/mentalpod Become a one-time or monthly donor via PayPal at https://mentalpod.com/donateYou can also donate via Zelle (make payment to mentalpod@gmail.com) To donate via Venmo make payment to @Mentalpod See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
If you're looking for an uncommon thinker, how about a tech industry veteran developing and selling landline phones in 2025 — and selling out of them in the process. Chet Kittleson is the co-founder and CEO of Tin Can, a Seattle startup making Wi-Fi enabled landline phones designed to let kids talk to friends and family with just their voices. No screens, no AI. GeekWire recognized Kittleson as one of our Uncommon Thinkers for 2025, a program presented in partnership with Greater Seattle Partners honoring inventors, scientists, and entrepreneurs transforming their industries in unexpected ways. In this episode, he talks about the moment at school pickup that sparked the idea, why his own kids don't own devices, what happened when he eliminated screens on family road trips, and the $12 million seed round led by Greylock that will fuel the company's next chapter. Related stories: Tin Can dials up another $12M to meet soaring demand for landline-style phone for kids Uncommon Thinkers: Tin Can is Chet Kittleson’s calling, and a way to foster deeper connections Uncommon Thinkers: Hope for the future from our 2025 honorees With GeekWire co-founder Todd Bishop; edited by Curt Milton. See omnystudio.com/listener for privacy information.
Kyle Kittleson brings the wow! In this fantastic, fun interview, Kyle shares wild and wonderful animal-training stories (yes, dolphins!) and how those lessons power his work as host of MedCircle—where he translates expert mental-health insights for everyday life—and creator of Baba Blast, a kids' series that builds empathy and resilience. We dive into grief, practical tools for mental health, and the magic of human–animal connection that Working Like Dogs listeners love. EPISODE NOTES: Feathers, Fins, and Four Paws: Empathy in Motion with Kyle KittlesonBecome a supporter of this podcast: https://www.spreaker.com/podcast/working-like-dogs-service-dogs-and-working-dogs-pet-life-radio-original--6668004/support.
CardioNerds kicks off its advanced therapies series with Chair of the CardioNerds Heart Failure Council, Dr. Jenna Skowronski, co-chair of the series, Dr. Shazli Khan, and Episode FIT lead, Dr. Jason Feinman. In this first episode, they discuss the process of advanced therapies evaluation with Dr. Michelle Kittleson, Professor of Medicine and Director of Education in Heart Failure and Transplantation at Cedars-Sinai. In this case-based discussion, they cover the signs and symptoms of end-stage heart failure, the initial management strategies, and the diagnostic workup required when considering advanced therapies. Importantly, they discuss the special considerations for pursuing left-ventricular assist device (LVAD) versus heart transplantation as well as the multidisciplinary, team-based approach needed when advanced therapies are indicated. Notes were drafted by Dr. Shazli Khan. Audio editing for this episode was performed by CardioNerds Intern, Julia Marques Fernandes. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls Guideline-directed medical therapy (GDMT) is indicated in all heart failure patients and improves survival, but progressive symptoms and intolerance to GDMT can be warning signs of disease progression. The I-NEED-HELP mnemonic is an excellent reference when considering referral for advanced therapies (Figure). Management of acute decompensation includes diuretics and possible inotropic support. The inotropic agent used should be whichever best suits your specific patient. Milrinone may result in more hypotension, whereas dobutamine may result in more tachycardia. Tachycardic and normotensive patients may do better with milrinone, while hypotensive patients with normal heart rates may do better with dobutamine. Notably, DoReMi found no difference between milrinone and dobutamine for patients with cardiogenic shock. The initial diagnostic evaluation includes an echocardiogram, right heart catheterization (RHC), and often cardiopulmonary exercise testing (CPET) to objectively assess the status of the heart. Comprehensive labs, imaging and cancer screening are also needed to assess all other organs. When making the decision to pursue advanced therapies, always ask: Is the heart sick enough? Is the rest of the body well enough? These two questions provide a framework to guide if patients are optimal candidates for transplant versus LVAD. The advanced therapies evaluation is a team sport! Patients will meet not only with advanced heart failure cardiologists, but also cardiac surgeons, psychiatrists, social workers, nutritionists and pharmacists. All team members are of critical value in the process. Notes 1.) What are the key features of advanced cardiomyopathy, and when should providers consider referral for advanced therapies? Advanced cardiomyopathy may present as recurrent hospitalizations for decompensated heart failure, intolerance to GDMT with symptomatic orthostasis and hypotension, and progressive symptoms of heart failure despite medical therapy. The I-NEED-HELP mnemonic is a helpful tool to identify patients at risk of heart failure and is defined as follows: Need for Inotropic support, New York Heart Association (NYHA) Class IV symptoms, End-Organ Dysfunction, Ejection fraction
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/FRU865. CME/NCPD/CPE credit will be available until October 26, 2026.Implementing Targeted Therapies in Transthyretin Cardiac Amyloidosis: From Diagnosis to Stabilization In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/FRU865. CME/NCPD/CPE credit will be available until October 26, 2026.Implementing Targeted Therapies in Transthyretin Cardiac Amyloidosis: From Diagnosis to Stabilization In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/FRU865. CME/NCPD/CPE credit will be available until October 26, 2026.Implementing Targeted Therapies in Transthyretin Cardiac Amyloidosis: From Diagnosis to Stabilization In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/FRU865. CME/NCPD/CPE credit will be available until October 26, 2026.Implementing Targeted Therapies in Transthyretin Cardiac Amyloidosis: From Diagnosis to Stabilization In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
In this episode of Between Us Moms, we sit down with Chet Kittleson, dad, entrepreneur and founder of Tin Can — a modern take on the landline phone, created to give kids voice-to-voice connection without the distraction of apps, games, or social media.Chet shares the journey behind Tin Can: how a simple observation at a school pick-up line led to an idea for rethinking how kids and families communicate in a hyper-digital world. He talks candidly about how his own experiences informed his mission to build “all talk, no smarts.”We dive into key parenting questions like:How do we strike a balance between giving our kids connection and guarding against screen overload?What does independence look like for a kid in today's tech landscape?How can parents set up a communication device that supports friendship, planning, and voice-to-voice interaction — without opening the floodgates of apps and notifications?You'll hear practical tips, real-life stories from Chet's family, and inspiration for making intentional tech choices in your home. Whether you're gearing up for the “first phone” conversation, delaying a smartphone, or simply looking for healthier ways to connect — this conversation offers a refreshing lens and actionable ideas for families.Tune in and join us for a thoughtful, hopeful look at how we can reclaim meaningful connection in a world full of screens.Resources mentioned in the episode:Learn more about Tin Can and how it works: Tin CanFollow Chet's thoughts on parenting, tech, and childhood at his LinkedIn profile. LinkedIn+1This is a must-listen for every parent navigating the intersection of childhood, phones and connection.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
He's spent his career interviewing the world's leading mental health experts, but Kyle Kitson still struggles with depression, codependency, and self-sabotage. The difference? Now he has the framework to actually work through it. From marine animal training to mental health education, his journey proves that knowledge without application is just entertainment. This conversation covers the tiny habit formula that actually sticks, the animal training rule that stops you from setting yourself up to fail, and why approaching your mind with curiosity instead of judgment changes everything. Real talk about doing the work. Read the show notes for today's episode at terricole.com/774
This episode of ITE Talks Transportation dives into the newly released 12th edition of the ITE Trip Generation Manual. Guests Chris Brehmer of Kittleson & Associates and Eric Tripi of GHD highlight how the manual reflects multimodal travel patterns, with expanded data on walking, transit, and emerging land uses. They discuss new additions such as trip rates for fast-food restaurants, dog parks, and data centers, while also addressing how trends like hybrid work, e-commerce, and changing healthcare design are reshaping trip generation. They also expand on the benefits of the web app, the importance of submitting local data, and how evolving technology will shape future editions.
On this week's episode of Nina's Got Good News, host Nina B. Clarke is joined by her Good News VIP Guest, Chet Kittleson! Chet is the co-founder of Tin Can, a screen-free phone for kids that brings back the charm of land lines, minus the cords and with a lot more freedom. Nina and Chet discuss his inspiration to create a modernized landline phone, and the many benefits of providing your child with a Tin Can phone before making the jump to a smartphone. They discuss the “phone-life balance” for kids and parents alike, advice given to him by Jonathan Haidt of The Anxious Generation, and much more! ——————— This week's episode of Nina's Got Good News is brought to you by MASA Chips! MASA are classic tortilla chips handmade with only three natural ingredients— organic corn, grass fed tallow, and sea salt. Visit them online at masachips.com, and use code GOODNEWS at checkout for 20% off your purchase. ——————— Follow Nina on Instagram: www.instagram.com/ninabclarke/ Visit Nina's blog: www.ninabradleyclarke.com Visit Nina's LTK shop: https://www.shopltk.com/explore/NinaBClarke Purchase a Tin Can for your family: https://tincan.kids/#picker-outer Follow Tin Can on Instagram: https://www.instagram.com/tincan.kids Check out Chet and his family on The Today Show: https://www.today.com/video/why-parents-are-dialing-it-back-with-landlines-for-their-kids-247082053918
This episode of ITE Talks Transportation dives into the newly released 12th edition of the ITE Trip Generation Manual. Guests Chris Brehmer of Kittleson & Associates and Eric Tripi of GHD highlight how the Manual reflects multimodal travel patterns, with expanded data on walking, transit, and emerging land uses. They discuss new additions such as trip rates for fast-food restaurants, dog parks, and data centers, while also addressing how trends like hybrid work, e-commerce, and changing healthcare design are reshaping trip generation. They also expand on the benefits of the web app, the importance of submitting local data, and how evolving technology will shape future editions.
This week, I'm welcoming back my friend, neighbor, and encourager, Heather Kittleson! Heather shares her journey from addiction to launching her nonprofit, Fortitude Ministries. We dive into the real struggles moms and women are facing today, how culture has distorted our view of motherhood, and how to reset our hearts around Christ-centered living. Heather’s encouragement to "zoom out," reset priorities, and pursue an abundant life will leave you feeling seen and strengthened for your own journey. In this episode, we talk about: Why motherhood isn’t about the white picket fence dream How slowing down can bring lasting joy Learning to say no and prioritize well How to zoom out and see the bigger picture The importance of Christ-centered identity for ourselves — and for raising our kids Upcoming events from Fortitude Ministries, including the new Mother-Son Event! Helpful Links: Follow Heather on Instagram: Fortitude by Heather Stay connected with me on Instagram: Encourager Podcast Leave a review for the podcast: Apple Podcasts Sign up for the newsletter: Encourager Newsletter Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.
This week, I'm welcoming back my friend, neighbor, and encourager, Heather Kittleson! Heather shares her journey from addiction to launching her nonprofit, Fortitude Ministries. We dive into the real struggles moms and women are facing today, how culture has distorted our view of motherhood, and how to reset our hearts around Christ-centered living. Heather’s encouragement to "zoom out," reset priorities, and pursue an abundant life will leave you feeling seen and strengthened for your own journey. In this episode, we talk about: Why motherhood isn’t about the white picket fence dream How slowing down can bring lasting joy Learning to say no and prioritize well How to zoom out and see the bigger picture The importance of Christ-centered identity for ourselves — and for raising our kids Upcoming events from Fortitude Ministries, including the new Mother-Son Event! Helpful Links: Follow Heather on Instagram: Fortitude by Heather Stay connected with me on Instagram: Encourager Podcast Leave a review for the podcast: Apple Podcasts Sign up for the newsletter: Encourager Newsletter Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.
We're taking a break this week, but we'll be back next week with a brand-new episode. Provide superb outpatient care for your patients with HFrEF. Identify underlying causes of heart failure and titrate medications with ease. Dr Michelle Kittleson @MKittlesonMD (Cedars Sinai) breaks down the nuances of treating this common cardiac condition. Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments 00:00 Introduction 03:22 Case Presentation: Newly Diagnosed Heart Failure 07:26 Using Physical Exam Findings to Guide Diuresis 11:58 The Four Pillars of Guideline-Directed Medical Therapy for Heart Failure 15:07 Optimizing Therapy and Follow-Up in Heart Failure Patients 22:10 The Benefits of High-Intensity Initiation and Titration of Guideline-Directed Medical Therapy 28:02 Consideration of Other Medications 40:02 Referral to Advanced Heart Failure Specialist 49:11 Optimizing Therapy and Follow-Up 55:33 Conclusion and Book Recommendation Credits Writer and Producer: Deborah Gorth MD, PhD Infographic and Cover Art: Zoya Surani Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP Reviewer: Emi Okamoto MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Michelle Kittleson MD, PhD Sponsor: Mint Mobile Get your summer savings and shop premium wireless plans at MINTMOBILE. com/CURB. Sponsor: American College of Physicians Order ACP MKSAP today at acponline.org. Curbsiders Listeners who use promo code CORECS will receive a MKSAP gift pack with their subscription. Sponsor: Panacea Legal Learn more and schedule your free consultation at Panacea.Legal.
In this inspiring episode, Mandee Hamann sits down with Chet Kittleson, entrepreneur and founder of Tin Can, a company on a mission to help kids and families connect offline—without the interference of screens. Chet shares the story behind Tin Can's creation, the challenges of raising kids in a hyper-digital world, and how meaningful connection can be reclaimed through intentional, tech-free moments.From the inspiration behind the simple-yet-powerful Tin Can to the importance of curiosity, trust, and communication in parenting, this conversation is full of encouragement and practical insight. Whether you're just starting your screen-free journey or looking for new ways to strengthen family bonds, Chet's message will resonate deeply.PricingThe pre-order price is $75, and then it'll go to $100 after that. Tin Can now has a free plan for families who only want/need Can2Can calling (ie. the ability to call/receive calls from Tin Cans). The Party Line Plan, where they can add normal numbers to their approved network (cell phones, landlines, 911, etc) is $9.99 / month. Use the invite code SCREENSTRONG to receive a free month of service. You can also email Chet with any questions, comments, or ideas at chet@tincan.kids.Support the showDon't forget to subscribe, rate, and leave a review if you enjoy the episode. Your feedback helps us bring you more of the content you love. Stay Strong! Get your copy of the BRAND NEW KBS Home Edition! Start your ScreenStrong Journey today! Become a Connect Member to get access to our exclusive online forum, the 30-Day ScreenStrong Challenge, LIVE webinars with medical experts, and the entire ScreenStrong library of videos, audio clips, interviews, e-books, handouts, and more! Want to help spread the ScreenStrong message to your community? Consider becoming a ScreenStrong Ambassador! ScreenStrong Tech Recommendations Gabb Wireless—Smartphone Replacement (use code STRONG for discount) Canopy—Device Filter (use code STRONG for discount) Production Team: Host: Melanie Hempe Producer & Audio Editor: Olivia Kernekin
Jennie is joined by "Pretty Little Liars" actress and podcast host Sasha Pieterse, TV host and author Samantha Harris, and cardiologist Dr. Michelle Kittleson to discuss why women need to be their own health advocates. The ladies are talking about the importance of listening to our bodies, why you should pursue additional medical opinions, and the heart-related risks women need to be aware of. A conversation that helped save a life the day it was recorded. Follow the "I Choose Me" Podcast on Instagram and TikTok Follow Jennie on Instagram, TikTok, and FacebookSee omnystudio.com/listener for privacy information.
Jennie is joined by "Pretty Little Liars" actress and podcast host Sasha Pieterse, TV host and author Samantha Harris, and cardiologist Dr. Michelle Kittleson to discuss why women need to be their own health advocates. The ladies are talking about the importance of listening to our bodies, why you should pursue additional medical opinions, and the heart-related risks women need to be aware of. A conversation that helped save a life the day it was recorded. Follow the "I Choose Me" Podcast on Instagram and TikTok Follow Jennie on Instagram, TikTok, and FacebookSee omnystudio.com/listener for privacy information.
This episode covers: Cardiology This Week: A concise summary of recent studies Dual antiplatelet therapy in 2025 Optimal communication with patients Snapshots Host: Emer Joyce Guests: Carlos Aguiar, Michelle Kittleson, Gilles Montalescot Want to watch that episode? Go to: https://esc365.escardio.org/event/1798 Disclaimer ESC TV Today is supported by Bristol Myers Squibb. This scientific content and opinions expressed in the programme have not been influenced in any way by its sponsor. This programme is intended for health care professionals only and is to be used for educational purposes. The European Society of Cardiology (ESC) does not aim to promote medicinal products nor devices. Any views or opinions expressed are the presenters' own and do not reflect the views of the ESC. Declarations of interests Stephan Achenbach, Emer Joyce, Michelle Kittleson and Nicolle Kraenkel have declared to have no potential conflicts of interest to report. Carlos Aguiar has declared to have potential conflicts of interest to report: personal fees for consultancy and/or speaker fees from Abbott, AbbVie, Alnylam, Amgen, AstraZeneca, Bayer, BiAL, Boehringer-Ingelheim, Daiichi-Sankyo, Ferrer, Gilead, GSK, Lilly, Novartis, Pfizer, Sanofi, Servier, Takeda, Tecnimede. Davide Capodanno has declared to have potential conflicts of interest to report: Bristol Myers Squibb, Daiichi Sankyo, Sanofi Aventis, Novo Nordisk, Terumo. Gilles Montalescot has declared to have potential conflicts of interest to report: research funds for Action Groupe or honoraria from Abbott, Amgen, AstraZeneca, Bayer, BMS, Boehringer-Ingelheim, Celecor, CSL Behring, Hexacath, Idorsia, Lilly, Novo Nordisk, Pfizer, SMT, Terumo. Steffen Petersen has declared to have potential conflicts of interest to report: consultancy for Circle Cardiovascular Imaging Inc. Calgary, Alberta, Canada. Emma Svennberg has declared to have potential conflicts of interest to report: Abbott, Astra Zeneca, Bayer, Bristol-Myers, Squibb-Pfizer, Johnson & Johnson.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/QTM865. CME/NCPD/CPE credit will be available until January 22, 2026.Don't Fail Them Now: Bridging Diagnostic and Treatment Gaps in Transthyretin Cardiac Amyloidosis[JAC_Logo] In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/QTM865. CME/NCPD/CPE credit will be available until January 22, 2026.Don't Fail Them Now: Bridging Diagnostic and Treatment Gaps in Transthyretin Cardiac Amyloidosis[JAC_Logo] In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/QTM865. CME/NCPD/CPE credit will be available until January 22, 2026.Don't Fail Them Now: Bridging Diagnostic and Treatment Gaps in Transthyretin Cardiac Amyloidosis[JAC_Logo] In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/QTM865. CME/NCPD/CPE credit will be available until January 22, 2026.Don't Fail Them Now: Bridging Diagnostic and Treatment Gaps in Transthyretin Cardiac Amyloidosis[JAC_Logo] In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE information, and to apply for credit, please visit us at PeerView.com/QTM865. CME/NCPD/CPE credit will be available until January 22, 2026.Don't Fail Them Now: Bridging Diagnostic and Treatment Gaps in Transthyretin Cardiac Amyloidosis[JAC_Logo] In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from BridgeBio Pharma, Inc.Disclosure information is available at the beginning of the video presentation.
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:https://www.mycme.com/courses/management-of-amyloid-cardiomyopathy-and-polyneuropathy-9813SummaryIn this CME/CE podcast episode, Cardiologist Dr. Michelle Kittleson and Neurologist Dr. Chafic Karam discuss the multidisciplinary management of transthyretin amyloidosis (ATTR). They explore how ATTR affects both the heart and the nervous system, focusing on recognizing symptoms, diagnosing the disease, and managing treatment. Dr. Karam shares insights on peripheral neuropathy caused by amyloidosis, including clues that suggest amyloidosis over more common neuropathies. Dr. Kittleson highlights how cardiologists assess and manage TTR cardiomyopathy, emphasizing the importance of early diagnosis and the evolving therapeutic landscape. Together, they discuss the collaborative nature of care, the impact of new therapies on clinical outcomes, and the importance of raising awareness for ATTR.Learning ObjectivesDescribe the correct diagnostic algorithm for suspected ATTR, including interpretation of the monoclonal protein screen and indications for biopsy and genetic testingInitiate appropriate management, including disease-directed therapy and appropriate cardiac care, or referral when indicatedThis activity is accredited for CME/CE CreditAssociation of Black Cardiologists, Inc. (ABC) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.Association of Black Cardiologists, Inc. designates this enduring material for a maximum of 0.25 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners® (AANP) through the joint providership of the National Association for Continuing Education (NACE) and ABC. NACE is accredited by the AANP as an approved provider of nurse practitioner continuing education. Provider number 121222. This activity is approved for 0.25 contact hours (which does not include hours of pharmacology).For additional information about the accreditation of this program, please contact NACE at info@naceonline.com.Summary of Individual DisclosuresPlease review faculty and planner disclosures here.Disclosure of Commercial SupportThis educational activity is supported by an educational grant from Alnylam Pharmaceuticals Inc., and an educational grant from AstraZeneca Pharmaceuticals.Please visit http://naceonline.com to engage in more live and on demand CME/CE content.
Chet Kittleson, Co-founder and CEO of Far Homes, shares how the company is simplifying international home buying. Born from the pandemic's remote work trend, Far Homes helps people buy and sell homes abroad, starting with Mexico. They offer a thorough real estate search platform, connect buyers with local agents, and focus on high-demand markets like Cancun and the Riviera Maya. Far Homes aims to be the go-to for global cross-border purchase financing, with tools like the Financing Finder making the process easier. One thing Chet points out is that despite all the possibilities with technology, agents remain a vital part of the equation when it comes to buying real estate both abroad and domestically.More about Chet and Far HomesFar Homes is a real estate company that is making it easier to find and buy homes in international destinations in a world where more and more people can live and work anywhere. Founded by real estate industry veterans in 2022, the company is working to simplify the international home-buying and selling experience through a technology-powered marketplace. Far Homes has built a database of pre and new-construction, and existing homes for sale making it easy to find the home you want. The company has a bilingual customer service team who respond quickly, and a network of local, multi-lingual partner agents with experience helping buyers from outside the country navigate the home buying and selling process.Far Homes has raised more than $2 million from PSL Ventures, Redfin CEO Glenn Kelman, and DoorDash co-founder Evan Moore, among others.Chet is the CEO of Far Homes, a US-based real estate start-up focused on simplifying the international home-buying experience. Chet started Far Homes in 2022 when the rise of remote work gave more people than ever the opportunity to live and work anywhere in the world, dramatically increasing the need for support in finding and buying a home in another country. Prior to starting Far Homes, Chet spent 6 years at Redfin where he first led New Ventures, building off his strong background in partnerships to create millions of dollars in high-margin revenue before becoming the GM of Marketplaces. Connect with ChetFollow Far Homes on TwitterCheck out Far Homes
The clinical picture of an underrecognized disease Amyloidosis demystified. Learn the clinical clues that suggest possible amyloidosis and how to order the correct tests to diagnose this disease. We are joined by Dr. Michelle Kittleson who shows us the ropes of treating fibril accumulation, @MKittlesonMD (Cedars Sinai). Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments Introduction Case Presentation: Mr. Smith Differential Diagnosis of Heart Failure with Preserved Ejection Fraction Understanding Amyloidosis Clinical Clues and Red Flags for Amyloidosis Physical Examination Findings Workup for Amyloidosis Treatment Options AL Amyloidosis and Hematologist's Role ATTR Amyloidosis and Cardiologist's Role Other Therapies for TTR Amyloidosis Therapy on the Horizon Cost and Access to Tafamidis Alternative Therapies and Supplements Monitoring and Side Effects of Tafamidis Symptomatic Management and Anticoagulation Take Home Points Credits Written and Produced by; Deborah Gorth, MD, PhD Infographic and Cover Art: Meryl Gorth, RD, MPH and Deborah Gorth, MD, PhD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP Reviewer: Sai S. Achi MD MBA Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Michelle Kittleson, MD, PhD Sponsor: Panacea Visit panaceafinancial.com today to open your free account. Sponsor: Grammarly Make a bigger impact at work with Grammarly. Sign up and download for FREE at grammarly.com/PODCAST Sponsor: Rocket Money Stop wasting money on things you don't use. Cancel your unwanted subscriptions by going to RocketMoney.com/CURB.
The following question refers to Section 7.8 of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.The question is asked by Stony Brook University Hospital medicine resident and CardioNerds Intern Dr. Chelsea Tweneboah, answered first by Mayo Clinic Cardiology Fellow and CardioNerds Academy Chief Dr. Teodora Donisan, and then by expert faculty Dr. Michelle Kittleson.The Decipher the Guidelines: 2022 AHA / ACC / HFSA Guideline for The Management of Heart Failure series was developed by the CardioNerds and created in collaboration with the American Heart Association and the Heart Failure Society of America. It was created by 30 trainees spanning college through advanced fellowship under the leadership of CardioNerds Cofounders Dr. Amit Goyal and Dr. Dan Ambinder, with mentorship from Dr. Anu Lala, Dr. Robert Mentz, and Dr. Nancy Sweitzer. We thank Dr. Judy Bezanson and Dr. Elliott Antman for tremendous guidance.Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. Question #29 A 69-year-old man was referred to the cardiology clinic after being found to have a reduced left ventricular ejection fraction and left ventricular hypertrophy. For the last several months he has been experiencing progressively worsening fatigue and shortness of breath while getting to the 2nd floor in his house. He has a history of bilateral carpal tunnel syndrome and chronic low back pain. He takes no medications. On exam, his heart rate is 82 bpm, blood pressure is 86/60 mmHg, O2 saturation is 97% breathing ambient air, and BMI is 29 kg/m2. He has a regular rate and rhythm with normal S1 and S2, bibasilar pulmonary rales, and 1+ pitting edema in both legs. EKG shows normal sinus rhythm with a first-degree AV delay and low voltages. Transthoracic echocardiogram shows a moderately depressed LVEF of 35-39%, severe concentric hypertrophy with a left ventricular posterior wall thickness of 1.5 cm and strain imaging showing globally reduced longitudinal strain with apical sparring. There is also biatrial enlargement and a small pericardial effusion. A pharmacologic nuclear stress test did not reveal any perfusion defects. A gammopathy panel including SPEP, UPEP, serum and urine immunofixation studies, and serum free light chains are unrevealing. A 99mTc-Pyrophosphate scan was positive with grade 3 uptake. In addition to starting diuretics, what is the next most appropriate step for managing for this patient? A Start metoprolol succinate B Start sacubitril/valsartan C Perform genetic sequencing of the TTR gene D Perform endomyocardial biopsy Answer #29 Explanation The correct answer is C – perform genetic sequencing of the TTR gene. This patient has findings which raise suspicion for cardiac amyloidosis. There are both cardiac (low voltages on EKG and echocardiogram showing marked LVH with biatrial enlargement and small pericardial effusion as well as a characteristic strain pattern) and extra-cardiac (bilateral carpal tunnel syndrome and low back pain) features to suggest amyloidosis. The diagnosis of cardiac amyloidosis requires a high index of suspicion and most commonly occurs due to a deposition of monoclonal immunoglobulin light chains (AL-CM) or transthyretin (ATTR-CM). ATTR may cause cardiac amyloidosis as either a pathogenic variant (ATTRv) or as a wild-type protein (ATTRwt). Patients for whom there is a clinical suspicion for cardiac amyloidosis should have screening for serum and urine monoclonal light chains with serum and urine immunofixation electrophoresis and serum free light chains (Class 1, LOE B-NR). Immunofixation electrophoresis (IFE) is preferred because serum or urine plasma electrophoresis (SPEP or UPEP) are less sensitive. Together, measurement of serum IFE, urine IFE, and serum FLC is >99% sensitive for AL amyloidosis.
In this episode, Dr. Gurleen Kaur (medicine resident at Brigham and Women's Hospital and Director of CardioNerds Internship) and CardioNerds Academy interns Dr. Akiva Rosenzveig (medicine intern at Cleveland Clinic), Dr. Chelsea Tweneboah (medicine intern at Stonybrook University), student doctor Shivani Reddy (medical student at Western Michigan University), student doctor Diane Masket (medical student at Rowan School of Osteopathic Medicine), and student doctor Tina Reddy (medical student at Tulane University School of Medicine) discuss with Dr. Michelle Kittleson (Director of Education in Heart Failure and Transplantation, Director of HF Research, and Professor of Medicine at Cedars Sinai) about Mastering the Art of Patient Care. Dr. Kittleson shares pearls of wisdom from her book on topics including career transitions, mentorship, dealing with uncertainty, learning from mistakes, delivering difficult news, and being a woman and parent in medicine. This episode was planned by Dr. Gurleen Kaur and episode audio was edited by student doctor Tina Reddy. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron!
On this week's episode of GOLF's Subpar, Drew Kittleson joins former PGA Tour pro Colt Knost and jicky jack legend Drew Stoltz to recap Team Drew's second consecutive trip to the USGA Four Ball finals. -- Thanks to our official sponsor FanDuel. Step up to the tee and take a swing at betting the PGA TOUR on FanDuel. Right now, new customers can get a NO SWEAT BET up to ONE THOUSAND DOLLARS back in BONUS BETS. Go to FanDuel.com/SUBPAR and sign up. That's FanDuel.com/SUBPAR to get a NO SWEAT FIRST BET up to ONE THOUSAND DOLLARS! FanDuel, Official Betting Operator of the PGA TOUR. Disclaimer: 21+ in select states. First online real money wager only. $10 Deposit req. Refund issued as non-withdrawable bonus bets that expire in 14 days. Restrictions apply. See full terms at fanduel.com/sportsbook. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MI, NJ, OH, PA, IL, TN, VA), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-877-8-HOPENY or text HOPENY (467369) (NY), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV).