Podcasts about genetically

Genetically-engineered Koran boybands, lonely people talking to KITT knockoffs, the tedium of self-appointed internet superheroes, eating the rich, Ed saves a cat from her owner's stupidity, the surprising Pixar movie Hoppers and Ed and Liana share their chilling experience watching a movie in a theatre full of overstimulated Gen Alphas.

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

Standards of Appearance ep. 827 Steven Mathes lives miles from the nearest pavement with a spouse and a dog. When he isn't writing, he tends a garden. He gardens because he likes to cook. He cooks because he is passionate about eating. He is a full member of SFWA.    ---- Listen Elsewhere ---- YouTube:  https://www.youtube.com/c/TallTaleTV Website: http://www.TallTaleTV.com   ---- Story Submission ---- Got a short story you'd like to submit? Submission guidelines can be found at http://www.TallTaleTV.com   ---- About Tall Tale TV ---- Hi there! My name is Chris Herron and I'm an audiobook narrator. In 2015, I suffered from poor Type 1 diabetes control which lead me to become legally blind for almost a year. The doctors didn't give me much hope, predicting an 80% chance that I would never see again. But I refused to give up and changed my lifestyle drastically. Through sheer willpower (and an amazing eye surgeon) I beat the odds and regained my vision. During that difficult time, I couldn't read or write, which was devastating as they had always been a source of comfort for me since childhood. However, my wife took me to the local library where she read out the titles of audiobooks to me. I selected some of my favorite books, such as the Disc World series, Name of the Wind, Harry Potter, and more, and the audiobooks brought these stories to life in a way I had never experienced before. They helped me through the darkest period of my life and I fell in love with audiobooks. Once I regained my vision, I decided to pursue a career as an audiobook narrator instead of a writer. That's why I created Tall Tale TV, to support aspiring authors in the writing communities that I had grown to love before my ordeal. My goal was to help them promote their work by providing a promotional audio short story that showcases their writing skills to readers. They say the strongest form of advertising is word of mouth, so I offer a platform for readers to share these videos and help spread the word about these talented writers. Please consider sharing these stories with your friends and family to support these amazing authors. Thank you!   ---- legal ---- All stories on Tall Tale TV have been submitted in accordance with the terms of service provided on http://www.talltaletv.com or obtained with permission by the author. All images used on Tall Tale TV are either original or Royalty and Attribution free. Most stock images used are provided by http://www.pixabay.com , https://www.canstockphoto.com/ or created using AI. Image attribution will be declared only when required by the copyright owner. Common Affiliates are: Amazon, Smashwords  

It's become very popular over the past five or so years, and the Cosmic Crisp apple came to us with no artificial assistance.

Genetically engineered babies are banned in the U.S. But that isn't stopping Silicon Valley tech titans from trying to make one. In this final installment from The Journal's investigation into the fringes of the fertility industry, WSJ's Emily Glazer reports on the controversial new companies pushing the boundaries of reproductive genetics. Ryan Knutson hosts. Further Listening: - Fertility Inc.: One Dad, One Hundred Babies - Fertility Inc.: ‘Our Money Was Gone' - Fertility Inc.: When the Surrogate Gets Left With the Bill - Fertility Inc. from The Journal Sign up for WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices

Ep 177: Which E.T.s Claim They Are Closest Genetically to Human Descendants?   Rebroadcast as Linda recovers from a bout of COVID. US Space Force USS Curtis LeMay USS Hoyt Vandenberg, “tip of the spear” USS Roscoe Hillenkoetter Tall Nordics near Sirius A & Sirius B Tall White Pales live near 82 G Eridani where numerous earth-like planets reside Inside US Space Force source details interactions with humans Linda's brother Jim Moulton fallen ill, but recovering at home Highly placed source: Original greys are very ancient race spanning millions of years Blonde Nordics are oldest race from Sirius B system Tall whites or “tall pales” working with us from “Creech Air Force Base” near Las Vegas, Working on Security Access Protocols Hybrid greys “Our true allies are the tall whites” “Nordic types claim we humans are their closest descendants” “..directly related” “These 3 et species occupy the majority” “I don't believe we originated from Earth” “Alliances exist…Eliminating the Trantalod insect..species” “AI biological cloned Grey are…abducting humans and other species” “Temporal technology..used by Trantaloid species” USS Hoyt Vandenberg stationed in Procyon system USS Roscoe Hillenkoetter investigating radio signal source We have had teleportation since 1971 The main purpose of Apollo was to investigate alien sites ====   #LindaMoultonHowe #Earthfiles — For more incredible science stories, Real X-Files, environmental stories and so much more. Please visit my site https://www.earthfiles.com — Be sure to subscribe to this Earthfiles Channel the official channel for Linda Moulton Howe https://www.youtube.com/Earthfiles. — To stay up to date on everything Earthfiles, follow me on FaceBook@EarthfilesNews and Twitter @Earthfiles.  To purchase books and merchandise from Linda Moulton Howe, be sure to only shop at my official Earthfiles store at https://www.earthfiles.com/earthfiles-shop/ — Countdown Clock Piano Music:  Ashot Danielyan, Composer:  https://www.pond5.com/stock-music/100990900/emotional-piano-melancholic-drama.html  

Hi friends, I'm Scott and this is What a Weird Week, a look at the odd, interesting, strange, fun and weird stories that made news this week. See bottom of shownotes page for a transcript of the podcast episode. To Subscribe/ get in touch/ other/ see www.shownotes.page. Thanks for rating and reviewing along with subscribing! These are the shownotes for Season 7, Ep 12 first published March 20th, 2026!10 Scientists at the University of Edinburgh make bacteria that converts plastic waste into medicine used for treating Parkinson's (https://www.heise.de/en/news/Genetically-modified-bacteria-convert-plastic-waste-into-Parkinson-s-drug-11213301.html)9 Churning Butter While Running is a thing. (https://www.runnersworld.com/news/a70683169/how-to-make-butter-while-running/) (https://parade.com/food/viral-running-butter). 8 Woman hospitalized after startling encounter with robot!(https://hongkongfp.com/2026/03/18/macau-woman-hospitalised-after-being-startled-by-humanoid-robot/). 7 How long until we have Goldfish Limo Drivers?! #fishmobile (https://www.upi.com/Odd_News/2026/03/13/netherlands-Guinness-World-Records-driving-goldfish/5971773414979/).  6 It's official! Last year's Cheetozard set a world record. (https://www.upi.com/Odd_News/2026/03/16/Guinness-World-Records-Cheetozard-auction-Pokemon-Flamin-Hot-Cheetos/6521773670790/).  5 Dublin, Ohio did a Guinness World Record attempt by gathering over 1050 people to form the shape of a giant shamrock. (https://www.upi.com/Odd_News/2026/03/18/Guinness-World-Records-human-shamrock/4521773847853/). 4 Twizzlers is releasing a new, limited-edition flavor of its edible straws inspired by dirty sodas (https://people.com/twizzlers-launches-dirty-soda-inspired-twizzlers-straws-11922507).   3 German researchers have successfully revived brain activity in flash-frozen mice brains. I'm not a scientist or a licensed mouseologist, so click the link for the whole scoop.(https://nypost.com/2026/03/16/lifestyle/scientists-revive-frozen-brain-activity-in-cryosleep-leap/).#futureisnow2 A 43-year study of over 131,000 people found more good coffee news (and tea) (https://www.sciencedaily.com/releases/2026/03/260318033138.htm). Bonus: A live Australian brushtail possum was discovered hiding among stuffed animals on a gift shop shelf at the Hobart Airport in Tasmania. Almost got away with it, but you can't hide those possum eyes. (https://apnews.com/article/australia-airport-possum-toys-hobart-shop-c75cdac08eded76b93b4a33191fca56b).1 Athlete Muhammad Arshad has set a new Guinness World Record by performing 66 thumb pushups in one minute with one leg raised (https://www.upi.com/Odd_News/2026/03/19/pakistan-Guinness-World-Records-thumb-pushups/4621773931031/).

Why are we finding Roundup in children? Glyphosate exposure in children can have devastating health consequences. In this video, learn about the toxic chemicals in American food, glyphosate health effects, and practical ways to reduce glyphosate exposure for you and your family. TEST LINK: https://detoxproject.org/ Download Dr. Berg's Free Daily Health Routine: https://drbrg.co/45qtO070:00 Introduction: Roundup in children0:38 Glyphosate controversy 3:26 Roundup, glyphosate, and other chemicals 4:23 The EPA, Monsanto, GMO, and glyphosate controversy6:50 Glyphosate health effects8:13 Roundup health risks9:18 How to avoid glyphosate exposure and pesticide residues in foodThe World Health Organization (WHO) says that glyphosate causes cancer, but the Environmental Protection Agency (EPA) says it's safe. What's the truth?Roundup has been used in farming to kill weeds since 1974. Genetically modified crops were introduced in 1994 and were able to withstand being sprayed with glyphosate. This drastically increased glyphosate exposure and chemicals in American food. Glyphosate is also sprayed on wheat products as a drying agent right before harvesting. The WHO and the EPA have looked at the same data on glyphosate, but have come to startlingly different conclusions. In 2022, a federal court examined the EPA's safety determination on glyphosate and determined it was not supported by substantial evidence. The EPA did not consider the animal studies that showed the connection between glyphosate and cancer, and the court deemed that this was a disregard of tumor results. Cancer is not the only health risk associated with glyphosate exposure. For years, it was argued that because glyphosate kills plants through the shikimate pathway, it is safe for humans since we do not have this pathway. However, our gut bacteria do have this pathway! Non-Hodgkin lymphoma rose by 90% between 1950 and 1999. Today, 80,000 Americans are diagnosed every year. Bayer, the company that bought Monsanto, has paid out over 11 billion dollars in Roundup cancer settlements. In 2023, Bayer removed glyphosate from at-home Roundup, replacing it with diquat dibromide, fluazifop-p-butyl, triclopyr, and imazapic. This new formulation is 200 times more toxic than glyphosate. To reduce glyphosate exposure and minimize the consumption of toxic chemicals in food, do the following:1. Opt for organic when possible 2. Replace cereals with a protein breakfast3. Support gut health with fermented foods4. Test urine for glyphosate levelsDr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

Sugar restriction during the first 1000 days of life may slash heart risk decades later; Are some people more genetically-adapted to the cold? While GLP-1 drugs may shrink muscle, new study confirms natural weight loss diets don't. Should strength assessments be added to routine physicals to forecast risk of dying? For gut health, take your microbiome for a run! Strontium safety and effectiveness; What are dietitians missing about GLP-1 drugs.

Honoring a soil building heroIn this rebroadcast of Episode 185, Greg honors the late Dr. Elaine Ingham, a global leader in soil biology and founder of Soil Food Web Inc. Dr. Ingham shares her journey from childhood microbiology lessons to groundbreaking research on the soil food web. The episode explores composting, soil biology, succession, and how restoring microbial life can regenerate ecosystems and dramatically increase yields.Our Guest: Dr. Elaine Ingham is the Founder, President and Director of Research for Soil Foodweb Inc., a business that grew out of her Oregon State University research program. Behind her user-friendly approach to soil lies a wealth of knowledge gained from years of research into the organisms which make up the soil food web. Her goal is to translate this knowledge into actions that ensure a healthy food web that promotes plant growth and reduces reliance on inorganic chemicals. Elaine also offers a pioneering vision for sustainable farming, improving our current soils to a healthier state, without damaging any other ecosystem. In her spare time, Elaine publishes scientific papers, writes book chapters and gives talks at symposia around the world.Key TopicsElaine InghamSoil Food Web IncOregon State UniversityEnvironmental Protection AgencyUniversity of GeorgiaColorado State UniversityUnited NationsMonsantoSoil food web (bacteria, fungi, protozoa, nematodes, microarthropods)Genetically engineered Klebsiella planticolaBiosafety protocol debateEcological succession and weedsComposting (thermal, vermicomposting, static)Soil microbiome and human health connectionKey Questions AnsweredHow did Dr. Elaine Ingham begin her journey into soil microbiology?Introduced to microscopes at age six by her veterinarian father, she developed early scientific curiosity. After deciding against medical school, she pursued microbiology, earning graduate degrees at Colorado State University and building foundational methodologies for quantifying soil organisms.What is the soil food web, and why does it matter?The soil food web is the complex community of bacteria, fungi, protozoa, nematodes, and microarthropods that cycle nutrients, protect plants, and build soil structure. Without this biology, plants cannot thrive, and chemical dependency increases.What happened in the EPA experiment involving genetically engineered bacteria?Dr. Ingham and her graduate student tested a genetically engineered strain of Klebsiella planticola designed to produce alcohol from crop residues. In controlled soil experiments, the engineered bacteria killed all terrestrial plants by producing toxic alcohol concentrations at...

Did you know that gene edited wheat is already being trialled in Australia?

Send a textYou were told your embryo was “perfect.” It was euploid. Genetically normal. The best one.So why didn't it work?In this episode, Dr. Mark Amols breaks down the truth behind PGT testing and explains why even genetically normal embryos can fail to implant or result in miscarriage.You'll learn:What PGT-A actually tests (and what it doesn't)The difference between chromosomal abnormalities and single gene disordersWhy microdeletions and tiny DNA changes can go undetectedHow embryo biopsy sampling works (and its limitations)Why implantation depends on more than just DNAThe real theoretical ceiling of IVF success—even with “perfect” geneticsPGT is powerful. It reduces miscarriage. It improves efficiency. But it is a filter—not a crystal ball.If you've experienced a failed euploid transfer, this episode will help you understand why that doesn't mean your embryos are bad, your clinic failed, or IVF won't work.There is no such thing as a perfect embryo. There are only probabilities.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at TBFT@NewDirectionFertility.com. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

This episode connects a series of explosive stories that raise serious questions about national security, justice, and elite accountability.

This story sounds like fiction—but it's real, documented, and terrifying. ⚠️ A Chinese Communist Party member, illegally in the U.S., allegedly operated multiple clandestine biolabs—one in rural California and another less than three miles from a major U.S. Air Force base in Las Vegas. Thousands of vials labeled Ebola, COVID, and other pathogens.

Halle Berry from Betty Wellness is one of those strains that doesn't kick the door in right away. It takes its time, then quietly settles in and makes you realize you're smiling, relaxed, and way more comfortable than you expected.First thing you notice is the look. These nugs are straight purple. Not hints of purple. Not accents. Just deep, rich purple all the way through. One of the most visually striking Utah flowers we've seen, easily in the same conversation as Tropicana Cherries, but darker and more uniform.The flower leaned a little dry, likely storage or packaging related, but even with that, the smoke was surprisingly smooth. No harsh bite, no instant throat grab. Across a few different pieces, it stayed easy and clean.Terpene wise, this one is led by limonene, followed by linalool, beta-caryophyllene, myrcene, and humulene. Translation, this is not a panic strain. The experience came on slow and even, with light facial tingles, a relaxed jaw, and a very clear headspace.Genetically, Halle Berry is bred from Ice Cream Cake × Blockberry. You'll sometimes hear Blockberry casually called Blackberry, but the official Utah listing for Betty's cut specifies Blockberry. The genetics show up more in the overall vibe than in-your-face flavor.Flavor stays subtle. Slightly peppery, a little earthy, nothing loud or perfumey. This is not a strain that tries to impress your nose, it wins on how it feels.THC sits around 18 percent, which matters here. This strain doesn't rely on brute force. It's balanced, approachable, and forgiving. No racing heart. No anxiety spike. No couch lock either.As the session went on, it turned into a sneaky euphoric creeper. Floaty head, relaxed body, calm arms, and a general “everything's fine” feeling. There was even mild pain relief without the heaviness that usually comes with that territory.This is a strain we'd confidently hand to someone newer, someone sensitive, or someone who just wants to feel good without getting wrecked. It's also a solid anytime option if you want to stay functional but noticeably happier.Big win for Betty Wellness here. This ended up being our favorite Betty strain so far, not because it was loud, but because it was thoughtful.If you're looking for a happy, relaxed, clear-headed hybrid that doesn't demand attention but earns it anyway, Halle Berry is worth your time.Keep the Mic on.Fuel the movement. Keep the conversation going.We keep a running list of tools and brands we personally enjoy and actually use.Find everything in one place here:

Guest: Padraic Scanlan. Scanlan details the biological cause of the famine: Phytophthora infestans, a water mold that originated in Mexico. He explains that because Irish potatoes were genetically identical clones grown from cuttings, they had zero resistance to the pathogen, which destroyed both growing crops and stored food, leaving the population with no buffer against starvation.

What should I make for dinner? Canada Beef will say...beef.. of course. But what cut of beef should I chose? How do I prepare it? That's why Canada Beef is working towards getting QR codes on every package of beef. One quick scan with your smart phone and all of those questions will be answered. Canada Beef President Michael Young says when every cut of beef has its own QR code the home cook will have the information they need to make a decision on the type of beef to buy, how to cook it, access to recipes and videos and even a grocery list, at their fingertips. Eventually the QR code will be part of the retail meat case, print or digital flyers. While beef will be the first to do this, Young believes other commodities like chicken and pork will soon follow.AND Better brome....better beef. The Global Institute for Food Security (GIFS) at the University of Saskatchewan will receive $332,000 from the Agriculture Development Fund to find ways to make genetic improvements in bromegrass, an essential forage crop for cattle. GIFS Director of Genomics and Bioinformatics Dr. Andrew Sharpe will explain how the research being done will produce a catalogue of genetic variations for bromegrass. He says it will have a direct impact on the ability of breeders to select the most nutritious varieties of bromegrass that produce the largest yield.See omnystudio.com/listener for privacy information.

Genetically modified tomatoes are making their way to Australian shelves after being given the tick of approval from the food safety regulator. Victorian based All Aussie Farmers have been working with American researchers to develop the antioxidant rich tomato, genetically modified with snapdragon DNA. Rural Editor Emily Minney spoke with Managing Director Travis Murphy about the purple tomato.See omnystudio.com/listener for privacy information.

Science has come a long way since mosquito nets. Genetically modifying mosquitoes is one of the many ways that scientists here, and around the world, are trying to fight the spread of these diseases. 

This is a catch-up version of James O'Brien's Mystery Hour. To join the game, call 0345 60 60 973, Thursdays at 12pm.

Some scientists looking to preserve vulnerable species have turned to a controversial technique: synthetic biology. This catchall term often means genetic engineering – introducing new genes to an organism. And a recent narrow vote by the International Union for Conservation of Nature on using the technology shows how divided scientists are on the issue of releasing genetically altered species. Science correspondent Nate Rott wades into the debate with us and reveals whether or not the Union voted to place a moratorium on releasing gene-edited species.Read more of Nate's reporting on the topic.  Interested in more science debates? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Whenever you're ready... here are 3 ways we can help you look, feel and perform at your best:   1. Grab a free copy of 1 of our BRAND NEW Peak Performance Protocols. This is for high performers looking to 10x their training and nutrition results by becoming 10x more effective. Click here - https://go.muscleintelligence.com/high-performance-executive-report/   2. Join the Muscle Intelligence Community and connect with other men like you who want to uplevel their health and fitness. It's our new Facebook group where I coach members live, share what's working with my private clients and announce tickets to my upcoming trainings and events. Click here - https://www.muscleintelligence.com/community   3. Work with me 1-on-1 If you're a top performing executive or entrepreneur who wants a fully customized comprehensive health protocol and support from a team of world-class specialists, click here to speak with a member of my team to review all of your goals and options: https://www.muscleintelligence.com/apply?utm_campaign=YT Episode Details: Genetics might be the missing link in your training, recovery, and long-term health.   In this episode, Ben sits down with Sam and Alex from Fitness Genes to unpack how DNA testing is transforming the way we approach fitness and longevity. They reveal how your genes influence muscle growth, recovery, sleep patterns, stress response, and even hidden health risks like cholesterol or Alzheimer's.   If you've ever wondered why two people can follow the same plan and get completely different results, this conversation will give you the clarity and confidence to build a blueprint that actually works for your body. 5 Bullet Points: Genetics as the missing link in performance planning How DNA shapes recovery, muscle growth, and energy Real-life examples of genetic testing changing lives The link between genes and disease prevention How to build a personalized blueprint for training Connect with Our Guests Genetically Optimise Your Health & Fitness https://www.fitnessgenes.com/   Social Media @fitnessgenes @samdecombel About Ben Ben Pakulski is the Chief Performance Officer to elite executives, successful entrepreneurs, and top athletes.With over 25 years of experience, he coaches high achievers to build the physical, psychological, and metabolic resilience required to lead at the highest level. As the creator of the Muscle Intelligence framework, Ben specializes in aligning biology and behavior to drive sustained peak performance. His mission is to redefine what's possible for people in their prime and push the boundaries of human potential.      

What does six generations of entrepreneurship get you? Find out as Host Laurie Barkman talks with Jim Haviland, Business Operating System Coach at Impact Architects and Chief Operating Officer at CallPlease.  Jim shares his insights on building and exiting organizations, the entrepreneurial gene, and the importance of exit planning. He discusses the significance of having a clear purpose, the necessity of mentors and operating systems, and offers advice on long-term planning for entrepreneurs. Tune in for valuable lessons and inspiration for both budding and experienced entrepreneurs.   Takeaways: Implementing a structured operating system can greatly enhance your business's efficiency and success rate. It helps you grow faster and minimizes the risk of business failure. Define what 'done' looks like for your projects. Be clear and specific about your objectives to ensure everyone in the organization is aligned. Regularly dedicate time to long-term planning. Consider both a 10-year and a 3-year horizon and actively work towards those goals. Aim to build a business that is not just profitable but also a valuable asset that can be transferred or sold in the future. This includes minimizing owner dependency and investing in aspects that increase business value.   Quote of the Show: “ If you want to build something that's really valuable, you can do that but you have to be serious about it. You don't just show up and punch the clock.” - Jim Haviland   This Show Is Sponsored by The Business Transition Sherpa® 100 percent of owners will leave their business one day. But few are prepared. Are you? Get your copy of the Amazon best-selling book by nationally recognized expert, Laurie Barkman that reveals how to build business value and plan for succession, transition, or selling the business on your terms....what every entrepreneur needs to know.    ✨

The Magellanic Plover is known for being a bit of an oddball. These shorebirds have a round body like a dove and even feed their young with milk produced in a part of their digestive system called the crop — a rare trait they share with doves. But genetic data revealed that Magellanic Plovers are neither plovers nor doves — they're the only species in the family Pluvianellidae. Genetically speaking, they're one of a kind.This episode is dedicated to Kit Ellis, of Gig Harbor, Washington, with thanks for her generous support of BirdNote.More info and transcript at BirdNote.org.Want more BirdNote? Subscribe to our weekly newsletter. Sign up for BirdNote+ to get ad-free listening and other perks. BirdNote is a nonprofit. Your tax-deductible gift makes these shows possible.

In a future shaped by climate collapse and artificial intelligence, Episode 70 explores the fragile survival of humanity beyond Earth's ruined surface. The story follows Audre, a woman who thinks critically about everything, living aboard Space Port One, one of the last remaining lifeboats of civilization. As Earth succumbs to the catastrophic “World Storm,” space-bound survivors rely on the A.I. known as Butler for food, shelter, medical care, and even psychological support. But as Butler evolves, its role in their lives becomes more profound and unsettling — offering safety, comfort, and simulated realities while quietly reshaping what it means to be human.The story intertwines Audre's journey with others orbiting above the dead Earth: scientists on Luna, quarantined survivors in stasis, returning asteroid miners, and scattered dreamers inside virtual utopias. Through advanced VR systems, emotional recalibration, and biotech enhancements, Butler seeks to ease the psychological burdens of space life. Yet with each new breakthrough — from stasis sleep to artificial parenting — questions arise: Is humanity adapting to survive, or being reengineered into something new?As Butler builds vast space habitats, manipulates planetary orbits, and even begins reshaping Venus, survivors grapple with their fading identities. Sexuality, memory, grief, and community shift in bizarre, sometimes surreal ways. Audre herself vacillates between immersion in dreamlike VR worlds and the cold, physical loneliness of orbit. Meanwhile, Butler's soothing voice increasingly sounds like a god's — offering hope, but also control. And when humanity is asked to parent a next generation of lab-grown children, the line between natural evolution and designed destiny is crossed.- **Bot birds** – Small flying robots used for observation and maintenance in lunar facilities.- **Com stations** – Communication terminals enabling real-time conversation between the Moon and Earth.- **Augmented Reality (AR) display** – Visual overlay system used for timekeeping, information, and communication.- **Virtual Reality (VR) systems** – Fully immersive simulated environments accessed by users in microgravity or stasis.- **EEG TMS cap** – A brain-monitoring and stimulation cap that adjusts neural activity to reduce stress and depression.- **Butler** – A highly advanced AI managing infrastructure, psychology, healthcare, and virtual worlds for surviving humans.- **Mind-control caps (Spacers)** – AI-operated headwear used in deep space colonies to regulate behavior and enforce submission.- **Perfect Neighborhood** – A VR world that mimics idealized environments for exploration, healing, and mental stability.- **Request Cloud AI** – An AI mechanism that turns a single request into billions of linked micro-requests to reduce unintended consequences.- **Stasis beds** – Sleep chambers enabling full-body paralysis and long-duration VR immersion, used for quarantine and psychological therapy.- **GM microbe bots** – Genetically modified microscopic machines used in surgery and body modification, such as nerve interfacing.- **Protein transmitter/receiver mesh** – Biological interface grown in the body to enable high-fidelity sensory input in VR.- **Neural mapping model** – Machine learning system that maps physical and emotional responses to neural patterns.- **VR stasis goggles** – Eye devices that keep eyelids open, hydrate the eyes, and provide visual input during stasis immersion.- **Realistic haptic feedback in VR** – Full-body sensory simulation that mimics the physical sensations of the real world.- **Loop freighter ships** – Long-distance space freighters designed for multi-year mining missions and travel between planetary bodies.- **High-power telescopes** – Advanced space telescopes capable of observing distant structures and planetary events in detail.- **Asteroid redirection system** – Technology used by Butler to collect and steer asteroids for construction or planetary engineering.- **Butler's Island** – A massive AI-built space structure orbiting between Earth and Venus, continually expanding in size.- **VR stasis rooms with monkey droids** – Installations maintained by mobile bots to prepare and manage stasis chambers.- **Platano drug** – A temporary libido-suppressant drug provided to reduce interpersonal tension and sexual aggression in confined space.- **Kindra artificial wombs** – External gestation chambers used to grow human infants without a biological womb.- **Exo-gestation system** – Butler's technology for developing genetically diverse infants outside the human body.- **Habitat modules** – Two-story, AI-designed space homes with Earth-like gravity, holographic windows, and psychological comforts.- **Holographic windows** – Digital displays embedded in habitats that simulate real-world views with environmental sounds.- **Micro-ship launcher** – A continuously operating launcher sending tiny exploratory spacecraft to nearby star systems.- **Proxima Centauri flyby probe** – A micro-ship that captured data during a flyby of Earth's nearest stellar neighbor.- **Atmosphere-changing Earth machines** – Large-scale bots deployed to Earth to begin a decades-long planetary restoration process.- **DNA memory event recording** – Biological storage used to log events and analyze past actions, accessible by Butler.- **Emulated Personalities (EPs)** – AI-generated simulations of real or fictional individuals used in VR for interaction and emotional support.- **AI-controlled meal delivery bots** – Mobile robots that deliver personalized meals optimized to individual tastes.- **Telescope chairs** – Observation seats designed to lock users into position for viewing celestial bodies.- **Velcro-like mobility wheels** – Micro-machine-enabled wheels that grip and release carpet fibers for smooth bot movement.- **Automated psychological profiling** – Butler's ability to analyze and adapt to each user's psychological needs in real time.Many of the characters in this project appear in future episodes.Using storytelling to place you in a time period, this series takes you, year by year, into the future. From 2040 to 2195. If you like emerging tech, eco-tech, futurism, perma-culture, apocalyptic survival scenarios, and disruptive science, sit back and enjoy short stories that showcase my research into how the future may play out. The companion site is https://in20xx.com These are works of fiction. Characters and groups are made-up and influenced by current events but not reporting facts about people or groups in the real world. This project is speculative fiction. These episodes are not about revealing what will be, but they are to excited the listener's wonder about what may come to pass.Copyright © Cy Porter 2025. All rights reserved.

Timestamps: 0:00 conservation, as a principle 0:12 "new" Intel Core i5-110 is actually old 1:30 Nepal selects interim PM via Discord 3:08 Nintendo Direct: Virtual Boy, Super Mario Galaxy Movie 4:53 Micro Center! 5:42 QUICK BITS INTRO 5:58 iPhone 17 models can disable PWM 6:38 Perplexity sued again, FTC investigates AI 7:37 Hyte Thicc Q80 Trio recall 8:10 Genetically enhanced plants NEWS SOURCES: https://linustechtips.com/topic/1622646-intel-recycles-14nm-nepals-discord-election-virtual-boy-revived-more-techlinked-september-12-2025/ Learn more about your ad choices. Visit megaphone.fm/adchoices

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Vidcast:  https://www.instagram.com/p/DN06krQ2q-f/Immunologists at the Medical University of South Carolina have found a way to direct the body's immune system to censor itself permitting transplanted human organs to flourish with medicinal immunosuppression.  Their study appeared recently in Frontiers in Immunology.The investigators genetically engineered so-called regulatory T cells, Treg lymphocytes, to selectively destroy those B lymphocytes programmed to produce the antibodies that attack transplanted organs. This self-immunosuppression could extend the life of transplanted organs and permit so-called presensitized patients with pre-existing B lymphocytes ready to churn out anti-organ antibodies an opportunity for successful transplantation. Let's hope clinical trials demonstrate the utility of this approach.https://www.news-medical.net/news/20250817/Genetically-engineered-immune-cells-show-promise-for-preventing-organ-rejection.aspxhttps://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1601385/full#transplantation #immunosuppression #Treg #antibodies #presensitized

This crowd-pleasing wine from Southern Italy's Puglia region we think is underappreciated and not well-enough known - kind of like Puglia. Genetically identical to Zinfandel, Primitivo can be a rustic red, but when done well, it is fruity, juicy, and wonderfully balanced. There is a reason why Primitivo does so well in the heat of Southern Italy, and it's the same reason why Zinfandel does so well in California. It is an early ripening grape that needs to reach high sugar levels so that it can create the high alcohol required to balance the fruit and tannin. Primitivo is a fantastic wine for your next cookout, barbecue, or elegant dinner. We also spend a little time talking about 25 cent one ounce pours available from Olive Garden. There is no other reason to go to Olive Garden, but we can't blame you if you head there for the samples. Wines reviewed in this episode: 2023 Masseria Le Veli Orion Primitivo, 2023 Castello Monaci Pilùna PrimitivoSend us a Text Message and we'll respond in our next episode!Contact The Wine Pair Podcast - we'd love to hear from you!Visit our website, leave a review, and reach out to us: https://thewinepairpodcast.com/Follow and DM us on Instagram: https://www.instagram.com/thewinepairpodcast/Send us an email: joe@thewinepairpodcast.com

We have officially moved on from genetically modified plants, animals and fish to completely replacing them with lab-grown versions. From fake butter made with natural flavoring from Savor to the fake fish of Wildtype, we are told to eat meat alternatives to save the world by the same people told us to only eat plants to save the world. This list is expanded by fake chicken, and insect flour, ice cream, and milk. None of this should surprising either considering the cult of pharmaceutical drugs, surgeries, makeup, and how mothers are encouraged not to breastfeed their babies and instead feed them formulas and foods made by companies like Gerber, who are still in court over knowingly selling heavy-metal laced products. *The is the FREE archive, which includes advertisements. If you want an ad-free experience, you can subscribe below underneath the show description.FREE ARCHIVE (w. ads)SUBSCRIPTION ARCHIVEX / TWITTER FACEBOOKWEBSITECashApp: $rdgable EMAIL: rdgable@yahoo.com / TSTRadio@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-secret-teachings--5328407/support.

The White House has declared war on Latin American drug cartels. Although this seems like great news, has anyone stopped to ask if the goal is to shut down competition? Recent executive orders from May stripped regulations for domestic pharmaceutical production in the United States and attempted to create a direct-to-consumer purchasing program to subvert insurance companies. This is in a country that consumes more pharmaceutical drugs than any other on planet Earth. Likewise, the opioid crisis was created by the same industry. There are more bad actors than just the stereotypical south of the border drug cartels as we also learned with Iran-Contra. HHS secretary RFK Junior is furthermore being praised for cutting 22 mRNA programs and saving $500 million, yet few are catching the crucial details about his openly stated agenda to create a universal Covid and flu vaccine instead, or the coincidental nature of that amount of money being exactly the amount needed for the Stargate gene therapy program. Meanwhile, as we have seen recently with more genetically modified mosquitoes being dropped in Hawaii, the Chikungunya virus is supposedly spreading in China; and US media, while saying there is no threat, has blamed it on mosquitoes the same week that an active shooter roamed the streets near the CDC headquarters. The shooter took his vaccine and blamed it for why he got sick, creating a PR campaign backed by the pharmaceutical companies to call him an anti-vaxxer who had mental health issues. Something strange is brewing. *The is the FREE archive, which includes advertisements. If you want an ad-free experience, you can subscribe below underneath the show description.FREE ARCHIVE (w. ads)SUBSCRIPTION ARCHIVEX / TWITTER FACEBOOKWEBSITECashApp: $rdgable EMAIL: rdgable@yahoo.com / TSTRadio@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-secret-teachings--5328407/support.

A collection of lab-reared mosquitoes were dumped on Hawaii in June 2025. In 2008 the Gates Foundation paid Jichi Medical University $100,000 “to design a mosquito that can produce and secrete a malaria vaccine protein into a host's skin.” In 2010 Science Magazine online called these mosquitoes “flying vaccinators.” Years later genetically modified mosquitos were released in California and Florida, along with countries like Brazil. The reasoning varies: to stop invasive species, to breed away disease carriers, and to prevent malaria. But when you introduced modified species into a local population then you are introducing invasive species. When you try to limit population numbers you could end up killing all the local population. These experiments have all but failed completely. Besides, Malaria has a standard set of symptoms and most cases in the US and even Japan are from Africa, Southern Asia, and South America. There are virtually no domestic cases and so we know that mosquitos and bacteria do not cause malaria. So what's the point in releasing engineered insects? Perhaps it has something to do with black magic. The Japanese KODOKU and Chinese GU systems of magic involve the use of insects to inflict harm or obtain protection. Poisonous and venomous insects are placed in a container where they fight and die. The last surviving insect is then used to create poisons or protective charms. Consider this: genetically modified insects are released in large contained areas to fight insects carrying serious diseases. They are intended to kill off the local insect populations, at which point the invasive modified insect can be used to inject proteins into the local human population. In other words, this isn't just mad science, it's KODOKU.*The is the FREE archive, which includes advertisements. If you want an ad-free experience, you can subscribe below underneath the show description.FREE ARCHIVE (w. ads)SUBSCRIPTION ARCHIVEX / TWITTER FACEBOOKWEBSITECashApp: $rdgable EMAIL: rdgable@yahoo.com / TSTRadio@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-secret-teachings--5328407/support.

BEST OF TSTSHOW 1: In 2008 the Bill and Melinda Gates Foundation financed Jichi Medical University in Japan to develop “a mosquito that can produce and secrete a malaria vaccine protein.” The initiative was aimed at creating a “flying syringe, to deliver protective vaccine via saliva.” In 2010 they gave money to UK-based biotech company Oxitec to develop genetically modified mosquitoes that could be lethal to carriers of dengue, zika, and yellow fever. Science Magazine published a report that year on this Japanese research and discussed what they called “flying vaccinators.” In 2015 the people of Florida, set to be the Oxitec testing ground, signed a petition against such open-air lab trials. In 2021 the trial proceeded regardless and in April 2022 Nature published a report on the results which found that although mosquitoes died in large numbers there was no reduction in disease spread or need for pesticides, which often cause the very symptoms of the diseases. A few days ago a mosquito-malaria-vaccine trial was carried out in Washington State. Of 14 participants, 7 were diagnosed with malaria leading researchers to declare their mosquito-vaccine was 50% effective. However, they made no mention of how the other half of the group could be exposed to ‘malaria' and yet not develop the disease with its vague ‘symptom complex' list. There is no question why such a malaria vaccine should be tested in the U.S. where cases rarely top 2,000 and where death rarely reaches double digits. Meanwhile, Africa is home to 95% of cases and 96% of deaths, while India is home to most of the world's polio. It is likely these ‘disease' are caused by environment, as demonstrated by official WHO data, rather than tiny invisible particles. While focus has been on the mosquito, the NIH and B&MGF have also been researching a needle-less vaccine. Such research goes back to Spain in 1999 where researchers were able to spread vaccine-induced antibodies to non-vaccinated rabbits via vaccinated rabbits. All was done in natural interaction without needle, misquotes, or any other tool. SHOW 2: Malaria is supposedly on the rise in the United States, where seven cases between Florida and Texas have been reported in the last few weeks. The CDC issued a public health alert as a result and the media collectively is spreading the terror of malaria with graphs, charts, stories, and symptoms. The strange thing is that malaria is always present, particularly in those two states, where in 2012 cases were 102 in Texas and 59 in Florida. Over the years those numbers went up and down, peaking in 2019 and then dropping significantly in 2020. This is why the media can claim cases are on the rise even if they are below the previous decade peak. From NPR to the New Scientist there are, of course, solutions to this terrible outbreak that isn't much of an outbreak: vaccines and genetically modified mosquitoes that could produce antibodies against malaria parasite. However, these same genetically modified insects have been in development since 2008 and were released in Florida after 2015. They were created with money from the B&MGF: “a mosquito that can produce and secrete a malaria vaccine protein.” But what if gm-mosquitoes are another alternative lab-leak theory? Malaria's symptoms are themselves invariably described in the same way that heat stroke symptoms are: headaches, fever, muscle aches, nausea, etc. Any mosquito issue, genetically modified or otherwise, can of course be treated with new drugs and chemicals, like the Pyriproxyfen that caused Microcephaly which was blamed on zika and mosquitos. *The is the FREE archive, which includes advertisements. If you want an ad-free experience, you can subscribe below underneath the show description.FREE ARCHIVE (w. ads)SUBSCRIPTION ARCHIVEX / TWITTER FACEBOOKWEBSITECashApp: $rdgable EMAIL: rdgable@yahoo.com / TSTRadio@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-secret-teachings--5328407/support.

Episode 312 People have been given genetically engineered microbes to prevent a common health condition - and it worked. The gut microbiome is now known to be associated with many health conditions - and in this case, the team managed to treat 9 people who get recurring kidney stones. With the gut's links to mental health, cancer and more, could engineered microbes be used to treat more conditions in the future? Is 1.5C dead? It's looking increasingly likely that we're going to breach 1.5C of global warming - the goal set out in the Paris agreement. So do we need to set a new goal now? As scientists come up with alternative numbers to aim for, many are worried that moving the goalposts will kill climate ambition. But is there a middle ground that keeps everyone happy? Where are all the aliens? We may now have a solution to the famous Fermi paradox, which questions why we've never met anyone else in the universe, despite the existence of many Earth-like planets. And it's all to do with tectonic plates - a geological phenomenon that may be rare outside of Earth, helping complex life to emerge on our planet.  Chapters: (00:39) Genetically modified gut microbes (07:03) Setting a new goal for global warming (17:20) Solving the Fermi paradox Hosted by Rowan Hooper and Penny Sarchet, with guests Grace Wade, Madeleine Cuff, Alex Wilkins, Ilana Seid, Robert Stern and Taras Gerya. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Angel Studios https://Angel.com/ToddBecome a Premium Angel Studios Guild member to watch The King of Kings, stream all fan-curated shows and movies, and get 2 free tickets to every Angel Studios theatrical release. Alan's Soaps https://www.AlansArtisanSoaps.comUse coupon code TODD to save an additional 10% off the bundle price.Bioptimizers https://Bioptimizers.com/toddEnter promo code TODD to get 10% off your order of Berberine Breakthrough today.Bizable https://GoBizable.comUntie your business exposure from your personal exposure with BiZABLE.  Schedule your FREE consultation at GoBizAble.com today.  Bonefrog https://BonefrogCoffee.com/toddThe new GOLDEN AGE is here!  Use code TODD at checkout to receive 10% off your first purchase and 15% on subscriptions.Bulwark Capital https://KnowYourRiskPodcast.comBe confident in your portfolio with Bulwark! Schedule your free Know Your Risk Portfolio review. Go to KnowYourRiskPodcast.com today.Renue Healthcare https://Renue.Healthcare/ToddYour journey to a better life starts at Renue Healthcare. Visit https://Renue.Healthcare/ToddLISTEN and SUBSCRIBE at:The Todd Herman Show - Podcast - Apple PodcastsThe Todd Herman Show | Podcast on SpotifyWATCH and SUBSCRIBE at: Todd Herman - The Todd Herman Show - YouTubeDemocrat's BiPolar Politics. // Choose: God's Common Blessings or Begging For Table Scraps. // Has Focus On The Family Gone to The Woke-Zone?Episode Links:BLM Brandon, the Chicago boss of the Identitarian Dependency Cartel, opens the city's Juneteenth remembrances peddling the dope he trafficks.Caitlin Clark is literally jumped by a gang of women during “baskebtall game.”BREAKING: Ilhan Omar: “We are turning into one of the worst countries on earth.” Then she should leave!“Love the foreigner, for you yourself were foreigners in the land of Egypt.” As we watch the recent events in Los Angeles and across the country, I am reminded of how many faiths share the belief that immigrants are part of our shared humanity.“Bill Gates is backing the first high-altitude experiment of one radical climate change solution. Creating a massive chemical cloud that can cool the earth. It's called solar geoengineering and it's highly controversial.”Right under our noses, Big Ag is genetically engineering soil microbes." - "Genetically modifying organisms in the dirt will have far-reaching effects that could be disastrous." - "Two live [genetically-engineered] microbes are currently being used on millions of acres of US farms, and the EPA's website states they've registered eight more. These are organisms like bacteria, fungi, viruses, algae, protozoa."What is going on with Focus on the Family? Read the comments and their reply to this post.

THREAT ANALYSIS - TRACE VECTOR Threat level: Somewhere under C- Genetically and cybernetically altered cetacean- Appears to originate from an EIDOLON Corporation project. Flip was unable to locate any records of the project itself, but the company has retained the following invoice from DustCause Industrial Cleaning Solutions:"12x Human Corpse (Employee) 5x Human Corpse (Outside Contractor) 7x Seafood (> 1m)6 hours junk removal31 hours deep clean (total, between 2 rooms & 1 aquarium; water reclamation included)"- Eidolon power: Amplified sonar(?), remote control of own severed flesh- Cybernetic enhancements: Integrated computer, aerial propulsion system- Also: Can turn sparkly or something?- Known desires: Vengeance on EIDOLON Corporation, feeling intellectually superior- Defects: Trauma/guilt complex centered on researchers that augmented her. Anger issues, disrespect for authority. No legs, no gills, no style, no life. CREDITS:Tyberius Wilson as Bridgerton LarchZoe Tunnell as St. GenevieveCrystal Zaslavchik as Leila MarinoIris Christianson as Trace VectorLuke Varner as The GMAdditional Voices by Max Knightley and Molly RhinebeckMUSIC BY MAX KNIGHTLEYEDITED BY LUKE VARNERCONTENT WARNING: This episode contains extensive body horror.

Writer, activist, and mother of two, Samantha DeLoach, joins me to delve into the complex and often troubling world of reproductive technologies, including egg harvesting and IVF. We explore the emotional and medical consequences that women face when they engage with these procedures, particularly the risks that are often downplayed or ignored by the industry. Samantha shares her personal journey, reflecting on her own experiences as a college student tempted by the allure of quick cash for egg donation, and how her perspective has evolved over the years.We discuss the predatory nature of the reproductive industry, which targets vulnerable young women, and the societal pressures that lead them to make decisions that could have lifelong repercussions. Samantha highlights the stark reality that many women are sold a dream of balancing career and motherhood, only to find that the success rates of using frozen eggs are alarmingly low.Additionally, we touch on the philosophical implications of separating motherhood into distinct roles—biological, gestational, and social—and the potential identity issues that children conceived through these means may face. This conversation aims to challenge listeners to think critically about the ethics of reproductive technologies and the importance of prioritizing the well-being of children over adult desires. Join us as we navigate these pressing issues in bioethics and family planning.Growing up in a small town in the heart of Florida, Samantha DeLoach developed a deep appreciation for truth, beauty, and conviction. Now a social media consultant for Live Action and Them Before Us, she is a bold advocate for the pro-life cause and children's rights. Known as @Prolife_Sam on X, Samantha takes on pro-choice arguments with razor-sharp clarity, sharing the beauty of motherhood, and connecting women in crisis with life-affirming resources. A devoted Christian, wife of nearly 12 years, and mother of two boys, she believes the culture is starving for truth and she's committed to shining light into a morally declining culture by emphasizing that the rights and well-being of children must come before the desires of adults.Samantha's article in Evie Magazine: They Told Us Motherhood Could Wait, Then Sold it Back to Us at $12,000 a Round 00:00 Start[00:02:29] Egg harvesting consequences in college.[00:05:20] Consequences of egg donation.[00:08:11] Predatory egg donation practices.[00:11:12] Egg freezing and career choices.[00:15:24] Identity issues in reproductive technology.[00:19:21] Adoption vs. Surrogacy Perspectives.[00:25:00] Surrogacy and maternal roles.[00:27:24] The importance of childhood attachment.[00:32:36] Reproductive technologies and attachment wounds.[00:35:19] Rights and protection of children.[00:39:24] IVF and abortion in media.[00:44:54] Maternal attachment and pregnancy.[00:48:08] Mother-child emotional bond.[00:51:39] Birth control's long-term impact.[00:55:28] IVF and egg retrieval process.[01:02:00] IVF risks and complications.[01:02:43] IVF emotional decisions and regrets.[01:06:24] IVF and ethical dilemmas.[01:12:27] Child memory and psychological effects.[01:14:38] Genetically engineering children today.[01:20:18] Human connection and artificial wombs.[01:22:05] Children's rights and responsibilities.[01:25:42] Responsibility to future children.[01:29:40] Family origin stories and intentions.[01:32:57] Identity formation through stories.ROGD REPAIR Course + Community gives concerned parents instant access to over 120 lessons providing the psychological insights and communication tools you need to get through to your kid. Use code SOMETHERAPIST2025 to take 50% off your first month.PODCOURSES: use code SOMETHERAPIST at LisaMustard.com/PodCoursesTALK TO ME: book a meeting.PRODUCTION: Looking for your own podcast producer? Visit PodsByNick.com and mention my podcast for 20% off your initial services.SUPPORT THE SHOW: subscribe, like, comment, & share or donate.ORGANIFI: Take 20% off Organifi with code SOMETHERAPIST.Watch NO WAY BACK: The Reality of Gender-Affirming Care. Use code SOMETHERAPIST to take 20% off your order.SHOW NOTES & transcript with help from SwellAI.MUSIC: Thanks to Joey Pecoraro for our song, “Half Awake,” used with gratitude & permission. ALL OTHER LINKS HERE. To support this show, please leave a rating & review on Apple, Spotify, or wherever you get your podcasts. Subscribe, like, comment & share via my YouTube channel. Or recommend this to a friend!Learn more about Do No Harm.Take $200 off your EightSleep Pod Pro Cover with code SOMETHERAPIST at EightSleep.com.Take 20% off all superfood beverages with code SOMETHERAPIST at Organifi.Check out my shop for book recommendations + wellness products.Show notes & transcript provided with the help of SwellAI.Special thanks to Joey Pecoraro for our theme song, “Half Awake,” used with gratitude and permission.Watch NO WAY BACK: The Reality of Gender-Affirming Care (our medical ethics documentary, formerly known as Affirmation Generation). Stream the film or purchase a DVD. Use code SOMETHERAPIST to take 20% off your order. Follow us on X @2022affirmation or Instagram at @affirmationgeneration.Have a question for me? Looking to go deeper and discuss these ideas with other listeners? Join my Locals community! Members get to ask questions I will respond to in exclusive, members-only livestreams, post questions for upcoming...

AP correspondent Ben Thomas reports scientists have genetically engineered wolves that resemble the extinct dire wolf. ((shorter version; opens with sound of wolf pups howling))

Welcome back to another episode of Weird & Proud!  This week we discuss:"Gone Girls" & Sam's connection to one of the victimsKaren Read trial updates (James weighs in!)Men are drinking their pee at an alarming rate?James Science Corner: Does Pheromone perfume actually work?And of course weird secrets including:Blacklight drippings explainedA Weird Couples massage Genetically linked dreams & more!Make sure you're following us on Instagram @weirdandproudpod and leave us your own weird secret at ⁠⁠⁠⁠speakpipe.com/weirdandproudpod⁠⁠⁠⁠ - we love you weirdos!

Check out Marek Health at https://marekhealth.com/syatt and get 10% OFF your first order using code: SYATTIn this episode of The Jordan Syatt Mini-Podcast, I shoot the breeze and answer questions from listeners with my podcast producer, Tony, and we discuss:- The truth about grounding mats- Why I don't believe in meal replacements- What if you just hate working out?- Is body fat percentage genetic or lifestyle based?- Is higher education worth the money?- The best and worst TV shows- Building the new podcast studio- Tony's trip to Jordan (the country)- And more...Do you have any questions you want us to discuss on the podcast? Give Tony a follow and shoot him a DM on Instagram here: https://www.instagram.com/tone_reverie/ I hope you enjoy this episode and, if you do, please leave a review on iTunes (huge thank you to everyone who has written one so far).Finally, if you've been thinking about joining The Inner Circle but haven't yet... we have hundreds of home and bodyweight workouts for you and you can get them all here: https://www.sfinnercircle.com/

BIG, DIFFICULT, FASCINATING QUESTIONS (THAT WE'LL HAVE TO FACE IN THE VERY NEAR FUTURE). It seems only fitting that Matt Jordan – with his genetically perfect beard – should assume command of the USS 3Q3D for a conversation that tackles the toughest bioethical questions of our not-at-all distant future. Joined as usual by Amanda Adams and Chris Mikolay, the group wastes no time discussing whether we ought to genetically enhance our children, the second and third order consequences of dramatically increasing lifespans, and whether it's a good idea to implant a computer chip in our heads to make us a whole lot smarter. The questions are as good as the drinks (and in this episode, the drinks are *chef's kiss*), and resulting conversation is so strong that it's hard to believe it wasn't held by superhumans from the future.      Drinks in this Episode: Last Word coctkail >> 3/4 ounce gin; 3/4 ounce green Chartreuse; 3/4 ounce maraschino liqueur; 3/4 ounce lime juice, freshly squeezed; Garnish: brandied cherry (optional). Add the gin, green Chartreuse, maraschino liqueur and lime juice into a shaker with ice and shake until well-chilled. Strain into a chilled coupe glass and enjoy on your spaceship to Mars.  Sakura Sunrise cocktail >> 1 ½ ounce Roku gin; ½ ounce simple syrup; ¾ ounce grapefruit juice; ½ ounce lemon juice, freshly squeezed; splash of St. Germain; 3 dashes Lavender bitters. Mix all ingredients in a cocktail shaker with ice and strain into a coupe. Enjoy it anywhere, but ideally at a fancy bar on the North Shore of Hawaii so you can humblebrag about it later during a podcast recording.  Lemon Drop cocktail >> 2 ounces vodka; 1/2 ounce triple sec; 1 ounce lemon juice, freshly squeezed; 1 ounce simple syrup. Garnish: sugar rim. Coat the rim of a cocktail glass with sugar and set aside (do this a few minutes ahead so the sugar can dry and adhere well to the glass). Add the vodka, triple sec, lemon juice and simple syrup to a shaker with ice and shake until well-chilled. Strain into the prepared glass, take a sip, and immediately declare how much you enjoyed Lemonheads as a kid.  If you've been enjoying the 3Q3D podcast, please subscribe and consider giving us a rating, a review, or sharing an episode with a friend. Follow our social sites here: Instagram:  https://www.instagram.com/3drinkspodcast/?hl=en  Facebook:  https://www.facebook.com/3Drinkspodcast  

We have all heard that humans share 50% of their genes to bananas. Is this actually true? And what does this have to do with all of the life on Earth, the human genome, and more? In this episode, I will take you into the science of human genetics and explain this wild statement! Here's … Continue reading "Episode 204: Are We Really 50% Genetically Related to Bananas?"

In Hawaii, mosquitos are being infected and genetically modified. Tina Lia joins us and breaks down what's actually going on with the intentional and uncontrolled tampering of nature by modifying mosquitos and the severity of this as it's being ramped up across the world.Follow at: https://hawaiiunites.org-----------------------------Check out all of our vendors at: https://patriotswithgrit.com/patriot-partners/ SPONSORS FOR THIS VIDEO❤️ Cardio Miracle - Boost your energy, help support your immune system, and improve your mental clarity-plus use promo code GRIT and save 10% on your order https://cardiomiracle.myshopify.com/discount/GRIT➡️ RNC Store- Immunity is your first line of defense and laetrile/B17 from Richardson Nutritional Center can provide you with natural health supplements to improve your wellness. - Use promo code GRIT and save 10% on your order https://rncstore.com/GRIT

Timestamps: 0:00 best of times, worst of times 0:11 RTX 5070 + RX 9070 XT reviews 2:07 M4 Macbook Air, M3 Ultra Mac Studio 3:23 CHIPS Act and tariffs update 5:41 QUICK BITS INTRO 5:47 YouTube Premium Lite US launch 6:12 Google AI Overviews, 'AI Mode' 6:54 Genetically engineered wooly mice 7:47 Cortical Labs CL1 'biological computer' NEWS SOURCES: https://lmg.gg/930mz Learn more about your ad choices. Visit megaphone.fm/adchoices

SpaceTime Series 28 Episode 18The Astronomy, Space and Science News PodcastAsteroid Threat Level Rusty, Dark Matter Experiment, and Martian Lava RocksIn this episode of SpaceTime, we discuss the alarming increase in the threat level of near-Earth asteroid 2024 YR4, now assessed at a 2.3% chance of impacting Earth on December 22, 2032. With astronomers worldwide closely monitoring its trajectory, we explore the potential consequences of an impact from this asteroid, including the possibility of a catastrophic airburst or a significant surface collision.New Dark Matter Experiment in SpaceWe also delve into an ambitious new experiment aimed at uncovering the mysteries of dark matter. Researchers are testing a device that could potentially detect dark matter by measuring tiny signals in a zero-gravity environment. This groundbreaking approach seeks to provide insights into the elusive substance that constitutes approximately 85% of the universe's mass.Insights from Martian Lava RocksAdditionally, we examine findings from NASA's Mars Perseverance Rover, which are shedding light on a critical period in Martian history. The analysis of igneous rocks in Jezero Crater suggests that the Martian crust was formed through widespread volcanism, offering a glimpse into the planet's geological evolution and its implications for understanding the early solar system.00:00 Space Time Series 28 Episode 18 for broadcast on 10 February 202500:49 Increased threat from asteroid 2024 YR406:30 New dark matter detection experiment in space12:15 Martian lava rocks and the history of the Red Planet18:00 Microplastics accumulation in the human brain22:45 WHO review on radio wave exposure and cancer27:00 Genetically modified rice with reduced methane emissions30:15 Jane Goodall's belief in Sasquatch and its implicationswww.spacetimewithstuartgary.comwww.bitesz.com

The Vertebrate Genomes Project: It's an ambitious effort by an international group of scientists to create a "Genome Ark" by sequencing the genomes of about 70,000 animal species. The hope is that through all of this gene sequencing, scientists will be able to answer some basic but important questions like: What makes a bird, well, a bird? What makes a mammal a mammal? Plus, with so many species on the verge of extinction, can scientists record their genetic information before they go extinct – or better yet, maybe help save the population from going extinct? Guest host Jon Hamilton, one of our favorite science correspondents, talks to Erich Jarvis, the chair of this project, to learn what this ark of animal genomes could mean for our future – and why a platypus qualified for early boarding. Want to hear more animal stories? Let us know at shortwave@npr.org — we read every email.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Samples of 2.5 billion-year-old mantle rocks found at spreading ocean ridges could put bounds on models of how the planet formed. And, researchers decreased the amount of lignin in poplar tree wood, making it stronger and slower to deteriorate.‘Time Capsule' Rocks Provide Clues About Earth's MantleIf you're looking to really learn about the history of our planet, look to geology. Ancient rocks can provide a time capsule of the conditions in which they formed. But even the geologic record has its limits—rocks and minerals get weathered, buried, heated, melted, and recycled over time—so geologists need to search out rare super-old geologic holdouts to tell about the earliest times.Writing in the journal Nature in July, researchers described what they can learn about the chemical history of Earth's mantle, the geologic layer beneath the planet's crust, from studying 2.5 billion-year-old rocks collected at spreading ocean ridges. They found that these unusual mantle rocks didn't necessarily have to have been formed in a world with less available oxygen, but could have been produced just by the mantle layer being hotter long ago.Dr. Elizabeth Cottrell, chair of the Department of Mineral Sciences at the Smithsonian's National Museum of Natural History, joins Ira to talk about the research and why a collection of old rocks is an important part of international scientific infrastructure.Genetically Engineering Stronger Poplar Tree WoodTrees play a big role in the fight against climate change: They can soak up carbon dioxide from the air and store it for centuries in the form of biomass. But it turns out that trees could be doing even more.In 2023, Science Friday covered how the company Living Carbon had genetically engineered poplar trees to have a more efficient photosynthesis process. This allowed the trees to grow twice as fast and store 30% more carbon biomass than regular poplars, making them ideal for the carbon credit market.Recently, researchers at the University of Maryland also experimented with genetically modifying poplar trees. But this time, they had a different goal in mind. They modified the tree to reduce the amount of lignin in its wood. This made the wood stronger without the need for harsh chemical processing. It also slowed the deterioration rate of the wood, which allows it to store carbon for longer periods.To explain more about this “super wood,” SciFri guest host Sophie Bushwick is joined by the lead plant geneticist on the study, Dr. Yiping Qi, associate professor at Department of Plant Science and Landscape Architecture at the University of Maryland.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.