Podcasts about metabolic disorders

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into a series of significant announcements and strategic initiatives that are shaping the landscape of drug development and patient care.Starting with a notable investment move, Eli Lilly has announced a $3.5 billion manufacturing facility in Pennsylvania, marking a significant milestone in their "Lilly in America" initiative. This facility is set to focus on injectables and devices, reinforcing Lilly's dedication to expanding its manufacturing capabilities within the United States. These types of investments are increasingly crucial as they aim to enhance supply chain resilience and support the production of complex biologics and innovative therapies—a step that could prove pivotal in maintaining a competitive edge in the global pharmaceutical market.Meanwhile, Regeneron's Eylea franchise is encountering challenges with declining sales, even with the introduction of Eylea HD. This situation highlights the difficulties companies face in maintaining market share amidst fierce competition and evolving treatment paradigms in ophthalmology. It underscores the importance of continuous innovation and effective lifecycle management strategies to sustain product competitiveness in a rapidly changing industry environment.Takeda is also navigating turbulent waters with its ADHD medication Vyvanse facing generic competition. Despite this, Takeda maintains an optimistic outlook for future growth by narrowing the revenue gap between declining Vyvanse sales and contributions from new products. This transition is reflective of a broader industry trend where companies pivot towards novel therapeutics to offset revenue losses from patent expirations, exemplifying strategic adaptation in response to market dynamics.AstraZeneca's ambitious $18.5 billion obesity deal with China's CSPC exemplifies the growing focus on metabolic disorders driven by rising global obesity rates. This partnership not only reinforces AstraZeneca's expansion strategy into China but also highlights the increasing importance of addressing obesity—a major public health challenge with significant healthcare cost implications. The deal marks a strategic push to leverage advanced therapeutic approaches, particularly targeting GLP-1 and GIP receptors with long-acting dual agonists. Additionally, AstraZeneca's further $15 billion pledge for investments in Chinese cell therapies and radiopharmaceuticals is expected to enhance its capabilities in personalized medicine and expand its global presence across key therapeutic areas—a reflection of a broader industry trend towards asset-centric deals prioritizing targeted acquisitions over traditional mergers.Novo Nordisk's ongoing legal challenge against drug pricing provisions in the Inflation Reduction Act (IRA) is gaining momentum, with support from the U.S. Chamber of Commerce urging the Supreme Court to review the case. This legal battle underscores ongoing tensions between pharmaceutical companies and regulatory frameworks aimed at controlling drug prices, reflecting broader debates on healthcare affordability and access—a critical issue that continues to shape policy discussions across the industry.Across the Atlantic, CDMO Vetter's €480 million investment in a new plant in Germany signals robust growth in contract development and manufacturing services. This expansion aligns with increasing demand for outsourcing solutions in biopharmaceutical production, driven by complex manufacturing processes and capacity constraints faced by many biotech firms. Such investments are pivotal as they aim to enhance production capabilities and meet growing demands for innovative biologics.Quince Therapeutics recently experienced a setback with its steroid delivery technology for ataxia-telangiectasia, illustrating the Support the show

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into the latest innovations, strategic shifts, and regulatory updates shaping the industry.Johnson & Johnson's Tecvayli, a promising monotherapy for multiple myeloma, has shown remarkable efficacy in clinical trials. By reducing the risk of disease progression or death by 71% among patients resistant to anti-CD38 therapies, Tecvayli is setting a new standard in oncological treatment. This breakthrough underscores not only its potential as a standalone therapy but also highlights significant advancements in managing multiple myeloma—a cancer notoriously difficult to treat and manage.In regulatory developments, Sanofi has recently completed pricing negotiations with U.S. policymakers, gaining much-needed clarity on drug pricing regulations. However, Sanofi remains cautious as evolving policies could impact future operations. This scenario is emblematic of the broader industry challenge: navigating an uncertain regulatory landscape while maintaining stability and profitability in volatile markets.Astellas Pharma is adapting to its looming patent cliff for the prostate cancer drug Xtandi by focusing on innovation as a strategy for sustainable growth. With patent protection set to expire next year, Astellas emphasizes innovation over acquisitions for revenue protection, reflecting a broader industry trend towards long-term growth strategies rather than short-term gains.Meanwhile, Jazz Pharmaceuticals has sold a priority review voucher for $200 million, highlighting the persistent value of these vouchers which expedite FDA review processes. Such vouchers are becoming essential strategic assets as companies seek competitive advantages through faster market entry.On the technological front, Becton Dickinson's $110 million investment to expand syringe production capabilities demonstrates efforts to meet rising demand for injectable medications like GLP-1s. This initiative not only addresses immediate supply chain needs but also aligns with broader discussions about reshoring pharmaceutical manufacturing in the U.S., enhancing domestic production capabilities.Financially, strategic trends were a focal point at the recent J.P. Morgan Healthcare Conference. Although large-scale mergers and acquisitions were anticipated, none materialized, suggesting an evolving focus towards strategic partnerships and incremental innovations over mega-mergers among industry stakeholders.Looking ahead, AbbVie's projection of strong growth into the 2030s is driven by a robust pipeline and strategic initiatives. As companies navigate a complex landscape defined by innovation demands and regulatory changes, such outlooks underscore the industry's commitment to sustaining growth and innovation while improving patient outcomes through novel treatments and technologies.Italian pharmaceutical company Alfasigma's acquisition of rights to an injectable treatment for HSV encephalitis from a German biotech firm further exemplifies strategic investments aimed at expanding therapeutic portfolios with innovative solutions addressing critical health needs. This move is significant given the limited therapeutic options available for this severe condition.The Novo Nordisk Foundation's $860 million investment in Denmark's BioInnovation Institute underscores efforts to strengthen local biotech ecosystems. By nurturing homegrown biotech and deep tech companies, this initiative positions Denmark as a prominent hub for research and development while facilitating the translation of scientific discoveries into viable therapeutic solutions.Ocugen's promising mid-phase data for its gene therapy targeting eye disease positions it as a potential competitor against market leaders like Apellis and Astellas. The positive phase 2 results highlight gene therapy's growiSupport the show

Which care models will handle the scourge of metabolic disorders? Beyond the societal questions raised by this public health phenomenon, the real concern is whether traditional care models are capable of managing this group of conditions effectively and sustainably. This largely because traditional care models are episodic and put little focus on behaviour change that is dearly needed to reverse the trend. Among those who have realized it and are striving for alternatives, Ihsan Almarzooqi and his team at meta[bolic] stand out. Based in Dubai, they have developed and deployed a unique care model, which they aim to replicate in Europe, starting with the UK. Their approach blends cutting-edge diagnostics, remote monitoring, and a care pathway involving frequent interactions with medical staff—enough to drive long-term behavioural change. And its efficacy has been demonstrated through numerous studies published since its inception. Beyond this hybrid care model, what is striking about Ihsan and the meta[bolic] philosophy is their relentless focus on improving outcomes for patients and incorporating the latest care innovations to raise the bar. Up to the point of reducing their operational margin to extend their knowledge of each patient, as long as it improves the level of care. In this episode, we discuss what makes this care pathway unique, its implementation, the results, and how we can leverage traditional reimbursement schemes while still delivering a continuous and outcome-oriented care experience. An inspiring and thought-provoking conversation on what care models for metabolic disorders can be, despite the constraints posed by most health systems! Timeline: 00:00:00 - What led Ihsan to pioneer new care delivery models 00:06:03 - The extent of the metabolic diseases pandemic 00:10:39 - Why traditional care models fail to address metabolic diseases 00:16:49 - The components that make up the meta[bolic] care model 00:23:37 - How the meta[bolic] care model is funded in the UAE 00:30:57 - Ihsan's philosophy about evidence generation and how it is lived at meta[bolic] 00:33:28 - Scaling the meta[bolic] model to other geographies beyond the UAE 00:38:45 - How to keep patients engaged throughout their care journey 00:41:55 - Ihsan's wishes for the democratization of value-based care What we also talked about with Ihsan: Continuous glucose monitors (CGMs) GLP-1 agonists Labcorp p-Tau217 VO2 max test PromarkerD test As mentioned by Ihsan during the episode, you can have a read at Ground Truths by Dr. Eric Topol and his recent book Super Agers, an encyclopedia of the latest medical knowledge around longevity. Ihsan also recommends listening to Dr. Peter Attia's podcast The Drive, which investigates everything from exercise and nutritional biochemistry to cardiovascular health, cancer, cognitive health, mental and emotional well-being, and beyond. You may also read Ihsan's publication in NEJM Catalyst Innovations in Care Delivery alongside Hala Zakaria, and Ali Hashemi, on their hybrid care model to manage diabetes in the UAE. You can get in touch with Ihsan via LinkedIn, and follow meta[bolic]'s activities on their website, LinkedIn, Facebook, Instagram, and YouTube. ✉️ If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! ⭐️ And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms!

Send us a textGood morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into a landscape rich with scientific innovation, regulatory scrutiny, and strategic business decisions shaping the future of healthcare.Let's begin with Novartis, which has achieved a significant milestone by securing FDA approval for Itvisma. This is an intrathecal formulation of its gene therapy Zolgensma, designed to treat older patients with spinal muscular atrophy (SMA). Priced at $2.59 million, this approval is a critical advancement in gene therapy for SMA, broadening the treatment horizon for a wider patient demographic. Gene therapies are increasingly crucial in addressing rare genetic disorders, offering transformative potential in patient care. Novartis's SMA market expansion post-FDA approval of Itvisma not only enhances its SMA portfolio but also signifies growing acceptance towards gene therapies as viable treatment options for genetic disorders. Meanwhile, Novartis is strategically restructuring, planning to cut 550 jobs at a Swiss plant by 2027 while expanding its workforce in North Carolina. This move reflects broader industry trends toward optimizing global operations and investing in regions with strategic manufacturing capabilities.In the sphere of regulatory scrutiny, lawmakers are questioning the FDA's National Priority Voucher Program amid concerns about corruption and expedited reviews. This situation highlights ongoing challenges within regulatory frameworks to balance innovation speed with rigorous safety assessments. An investigation into the FDA's new priority review voucher program has been initiated due to concerns over corruption and expedited review processes potentially compromising drug safety. This inquiry could influence future regulatory frameworks and underscores balancing accelerated drug approvals with rigorous safety standards. Richard Pazdur expressed concerns about expedited drug approval programs' safety and legality as he takes on his new role as director of the FDA's Center for Drug Evaluation and Research. These initiatives aim to accelerate drug reviews but spark debate over patient safety implications—underscoring an ongoing tension between innovation speed and regulatory diligence.Turning to Novo Nordisk, their expansion of the Amycretin program demonstrates a commitment to tackling chronic conditions like diabetes. Following promising Phase 2 data showcasing dual agonist capabilities, Novo Nordisk is advancing pivotal trials focused on obesity. This strategic pivot aligns with market needs and scientific discoveries that could significantly enhance diabetes management options. Further emphasizing Novo Nordisk's commitment to diabetes management, their expansion of the amycretin program after promising Phase 2 results demonstrates the efficacy of a dual agonist originally focused on obesity. This underscores a trend toward multifunctional biologics addressing metabolic disorders by targeting multiple pathways—indicative of broader industry shifts towards integrated therapeutic approaches. Novo Nordisk's recent mid-stage clinical trial results for Amycretin—a weight loss treatment—are noteworthy as they demonstrated sustained efficacy over 36 weeks in type 2 diabetes patients without a plateau in weight loss. Analysts highlight its potential as a superior therapeutic option in the burgeoning weight loss market due to its durable solution for weight management.On a contrasting note, SK Life Science encounters regulatory hurdles as the FDA scrutinizes advertising practices related to its antiseizure medication Xcopri. This scenario underscores the complex interplay between marketing strategies and regulatory compliance within the pharmaceuticSupport the show

* Add FAAN to Anita's creds after Oct. 18.Guests: Anita Rich, DNP, RN, CHFN, CDCES, FAAN, and Jane DeMeis.Related resources:PCNA CKM tools and resources: https://pcna.net/resources/patient-education/patient-information/cardiovascular-kidney-metabolic-syndrome-resources/ 2025 ACC Expert Consensus Statement on Medical Weight Mgmt for Optimization of CV Health: https://www.jacc.org/doi/10.1016/j.jacc.2025.05.024 Adiponectin, Leptin and CV Disorders: (https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.314458Racial and Ethnic Disparities in Adult Obesity in the US: https://www.cdc.gov/pcd/issues/2019/18_0579.htmCardiometabolic Syndrome: A Global Health Issue: https://www.uspharmacist.com/article/cardiometabolic-syndrome-a-global-health-issueTaking Aim At Belly Fat: https://www.health.harvard.edu/newsletter_article/taking-aim-at-belly-fatGender Disparities in People Living with Obesity: https://pubmed.ncbi.nlm.nih.gov/34526743/ Systematic review and meta-analysis suggests obesity predicts onset of CKD: https://www.sciencedirect.com/science/article/pii/S0085253816307529AHA Weight-Loss Strategies for Prevention and Treatment of Hypertension: https://pubmed.ncbi.nlm.nih.gov/34538096/ Renal Fat Accumulation Assessed by MRI or CT and Metabolic Disorders: https://pmc.ncbi.nlm.nih.gov/articles/PMC12194363/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this enlightening conversation between Dimple Jangda and Dr. Alka Vijayan, the duo dives deep into the Ayurvedic perspective on thyroid health, PCOS/PCOD, hormonal imbalances, and women's wellness. They decode how modern lifestyle habits, late nights, stress, wrong diet trends, synthetic products, and over exercising, create Vata and Kapha imbalances leading to chronic disorders. Dr. Alka emphasizes aligning with circadian rhythm, understanding one's Prakriti, and restoring balance through wholesome food, mindful cooking, rest, and emotional regulation. This episode bridges ancient Ayurvedic wisdom with modern-day health struggles, inspiring women to reconnect with their natural cycles and self-care.

Inherited metabolic diseases aren't just for the young. James Nurse talks with François Maillot and Ida Schwartz about their systematic review revealing how IMDs can first be diagnosed well into older age. From Fabry disease to alkaptonuria, they discuss diagnostic delays, missed clues, and why it's time to think about geriatric metabolic medicine. Diagnosis of Inherited Metabolic Disease in Older Patients: A Systematic Literature Review Maria-Rita Moio, et al https://doi.org/10.1002/jimd.70038

Mit den kürzeren Tagen sinkt bei vielen Menschen nicht nur die Energie, sondern auch ihr Vitamin-D-Spiegel. Rutscht er zu sehr ab, hat das Folgen für Leistungsfähigkeit, Immunsystem und Stimmung.Eine neue Studie deutet darauf hin, dass Indoor-Training den im Winter üblichen Vitamin-D-Abfall messbar ausbremst. Kann Deine Fitness-Routine also das Vitamin-D-Supplement ersetzen? Am Ende der Folge bist Du auf Stand und weißt, was das für Dich und Deinen Vitamin-D-Haushalt bedeutet.Außerdem bekommst Du eine klare Strategie an die Hand, um die dunklen Monate von Oktober bis März energiegeladen (und mit vollen Vitamin-D-Speichern) zu überbrücken – statt im Wintermodus auf Reserve zu laufen.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Tools (Marks Empfehlungen):Vitamin-D-Selbsttest von Medivere.Vitamin-D-Präparat mit 2.000 IE von FormMed (vegane Variante).Weiterführende Inhalte:Download: Ratgeber NahrungsergänzungFolge 502: "Brauchen Sportler Nahrungsergänzung, Herr Ernährungsmediziner?" Mit Niels Schulz-RuhtenbergWissenschaftliche Literatur:Perkin OJ, Davies SE, Hewison M, et al. Exercise without weight loss prevents seasonal decline in vitamin D metabolites: The VitaDEx randomized controlled trial. Advanced Science. 2025;12(22):e2416312.Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry & Biology. 2014;21(3):319-329.Webb AR, Kazantzidis A, Kift RC, Farrar MD, Wilkinson J, Rhodes LE. Meeting vitamin D requirements in white Caucasians at UK latitudes: Providing a choice. Nutrients. 2018;10(4):497.Lin LY, Smeeth L, Langan S, Warren-Gash C. Distribution of vitamin D status in the UK: a cross-sectional analysis of UK Biobank. BMJ Open. 2021;11(1):e038503.de Oliveira LF, de Azevedo LG, da Mota Santana J, de Sales LPC, Pereira-Santos M. Obesity and overweight decreases the effect of vitamin D supplementation in adults: Systematic review and meta-analysis of randomized controlled trials. Reviews in Endocrine and Metabolic Disorders. 2020;21(1):67-76.Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3):690-693.Drincic AT, Armas LAG, Van Diest EE, Heaney RP. Volumetric dilution, rather than sequestration best explains the low vitamin D status of obesity. Obesity (Silver Spring). 2012;20(7):1444-1448.Ekwaru JP, Zwicker JD, Holick MF, Giovannucci E, Veugelers PJ. The importance of body weight for the dose response relationship of oral vitamin D supplementation and serum 25-hydroxyvitamin D in healthy volunteers. PLoS One. 2014;9(11):e111265.Sun X, Cao ZB, Taniguchi H, Tanisawa K, Higuchi M. Effect of an acute bout of endurance exercise on serum 25(OH)D concentrations in young adults. Journal of Clinical Endocrinology & Metabolism. 2017;102(11):3937-3944.____________Shownotes und Übersicht aller Folgen.Trag Dich in Marks Dranbleiber Newsletter ein.Entdecke Marks Bücher.Folge Mark auf Instagram, Facebook, Strava, LinkedIn. Hosted on Acast. See acast.com/privacy for more information.

Dr. Hoffman continues his conversation with UK-based science journalist and author Caroline Williams, author of “Inner Sense: How the New Science of Interoception Can Transform Your Health.”

In this episode of the Intelligent Medicine podcast, Dr. Ronald Hoffman explores the concept of interoception with UK-based science journalist and author Caroline Williams. They discuss her latest book, “Inner Sense: How the New Science of Interoception Can Transform Your Health.” The conversation details the intricate relationship between the mind and body, the importance of bodily self-awareness, and how it impacts mental and physical health. Williams shares insights from her extensive research and practical strategies for enhancing interoception, such as controlled breathing exercises and body scans. They also touch on future advancements and therapeutic applications in the realm of interoception, offering listeners a comprehensive understanding of this emerging science and its potential to revolutionize healthcare.

Understanding Type 2 Diabetes (Type 2 Diabetes Mellitus), including Type 2 Diabetes Pathophysiology, normal glucose homeostasis, Type 2 Diabetes symptoms as well as complications. We also cover Type 2 Diabetes diagnostic criteria as well as treatment. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Type 2 Diabetes? 0:30 Normal Glucose Homeostasis3:02 Type 2 Diabetes Pathophysiology5:37 Type 2 Diabetes Symptoms9:12 Type 2 Diabetes Epidemiology10:17 Type 2 Diabetes Diagnosis11:43 Type 2 Diabetes Treatment / Management LINK TO MNEMONICS:https://www.youtube.com/watch?v=p-XE7PiwGgE&list=PLGNSE_HvIV4t7a33bbHN1fq-j_tge0GmpLINK TO SOCIAL MEDIA: https://www.instagram.com/rhesusmedicine/ReferencesLean, M.E.J., Leslie, W.S., Barnes, A.C., et al., 2018. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet, 391(10120), pp.541–551. https://doi.org/10.1016/S0140-6736(17)33102-1MSD Manuals, n.d. Diabetes Mellitus (DM) – Endocrine and Metabolic Disorders. MSD Manual Professional Edition. Available at: https://www.msdmanuals.com/professional/endocrine-and-metabolic-disorders/diabetes-mellitus-and-disorders-of-carbohydrate-metabolism/diabetes-mellitus-dmMogensen, C.E., et al., 2016. Glucose handling by the kidney in health and disease: review of recent findings. Current Opinion in Nephrology and Hypertension, 25(4), pp.292–296. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952418/Drugs.com, 2023. What is A1C? Normal vs dangerous levels, and how to lower it. Available at: https://www.drugs.com/medical-answers/what-a1c-normal-dangerous-levels-how-lower-3579748/Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice. #medicalmnemonic #medicalmnemonics #rhesusmedicine #studymedicine #studygram #medstudent #medicalschool

RFK Jr. fires entire vaccine panel, replaces with new picks—a catastrophe for public health, or a clean slate for transparent science? Red yeast rice for cholesterol; Is fish oil a no-no if you have atrial fibrillation? Study finds GLP-1 drugs associated with heightened macular degeneration risk; A novel nutrient—OEA—shows promise for reversing metabolic disorders, enhancing satiety.

Dr. Stephen LeBlanc of the Ontario Veterinary College at the University of Guelph joins Dr. Phil Cardoso of the University of Illinois for a chat about metabolic disorders and fertility.Links to publications mentioned in this episodeDairy Cattle Fertility (FE20)https://hoards.com/article-27434-dairy-cattle-fertility-(fe20).htmlBook details:121 pages8.5 x 11 inchesSoftcover, perfect boundFull colorISBN 978-0-9960753-3-6Copyright 2020Jessica Gordon papers on ketosis:Gordon et al. 2017, Effects of a combination butaphosphan and cyanocobalamin product and insulin on ketosis resolution and milk production.DOI: 10.3168/jds.2016-11925https://www.journalofdairyscience.org/article/S0022-0302(17)30149-2/fulltextGordon et al. 2013, Ketosis treatment in lactating dairy cattle. DOI: 10.1016/j.cvfa.2013.03.001https://www.sciencedirect.com/science/article/abs/pii/S0749072013000285?via%3DihubPascottini and LeBlanc 2020, Metabolic markers for purulent vaginal discharge and subclinical endometritis in dairy cows.DOI: 10.1016/j.theriogenology.2020.06.005https://pubmed.ncbi.nlm.nih.gov/32622204/Stephanie's (my student) video on Metricheck toolhttps://www.youtube.com/watch?v=jIhd8buSpHU&t=160sLeBlanc 2014, Reproductive tract inflammatory disease in postpartum dairy cows. DOI: 10.1017/S1751731114000524https://www.cambridge.org/core/journals/animal/article/reproductive-tract-inflammatory-disease-in-postpartum-dairy-cows/598913738F82C7FC94A92F60C7C80524New Zealand paper:Burke et al., Relationships between endometritis and metabolic state during the transition period in pasture-grazed dairy cows.https://pubmed.ncbi.nlm.nih.gov/20965352/

Focus Issue on Ischaemic Heart Disease, Diabetes and Metabolic Disorders

Subscriber-only episodeResources for the Community:___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55______________________________________________________________________The Provider Spotlight is a bonus series of shorter episodes featuring doctors and specialists from past sessions—think of it as 'doctor shorts.' With over 25k scripts for Zepbound written weekly, many new subscribers haven't seen our earlier episodes, which helps them catch up quickly. Thanks for your support! Dr. Salas-Whalen joins The Plus Sidez to break down PCOS, insulin resistance, and metabolic disorders—and how they're all connected. ______________________________________________________________________⭐️Mounjaro Stanley⭐️griffintumblerco.Etsy.comUse code PODCAST10 for $ OFF______________________________________________________________________Join this channel to get access to perks:   / @theplussidez______________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide  #GLP1 #Obesity #zepbound #wegovy Kim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

Focus Issue on Hypertension, Diabetes and Metabolic Disorders

Focus Issue on Dyslipidaemias, Diabetes, and Metabolic Disorders

This Real Science Exchange podcast episode was recorded during a webinar from Balchem's Real Science Lecture Series. You can find it at balchem.com/realscience. Dr. Santos begins with a timeline of events that occur during the cow's transition from the dry period to her exit from the fresh pen. He suggests that cows should be dried off at around 230 days of gestation, then moved to a closeup group at 250-255 days gestation which is around three to three-and-a-half weeks before calving. Dr. Santos recommends keeping multiparous cows separate from primiparous cows and feeding to minimize metabolic disorders in early lactation. After calving, cow health needs to be monitored for early detection and treatment of disease. In addition, diets that do not limit voluntary dry matter intake should be fed. During the early postpartum period, controlling excessive weight loss and lipid mobilization is the goal.  (00:27) What is the association between time spent in the closeup pen and disease? Research shows that around three to four weeks in the prepartum group is associated with the lowest risk of morbidity, maximum milk yield and highest pregnancy rates. How does a change in body condition during the first 65 days in milk impact cyclicity? How does 90-day milk yield impact cyclicity? Cows that lose one or more units of condition are less likely to be cyclic at the end of the voluntary waiting period. There is a small statically positive association between milk yield and cyclicity. Dr. Santos' first take-home message is to avoid excessive body condition loss after calving. Cows should lose no more than 0.5 body condition units from the week before calving to the first AI. This can be accomplished by minimizing over-conditioned cows at dry-off and reducing the risk of disease in early lactation.  (6:13) What about feed efficiency? Dr. Santos describes experiments comparing the 25% most efficient to the 25% least efficient cows. All cows produced the same amount of energy-corrected milk, but the most efficient cows ate four kilograms less feed each day. The risk of morbidity and the culling rate was the same for both groups, as was reproductive performance. Dr. Santos suggests we should not be afraid of selecting for feed efficiency while still optimizing intake in early lactation.  (18:23) Morbidity negatively impacts intake in early lactation. Around one-third of cows are affected by disease in the first three weeks of lactation and almost 80% of the first disease diagnoses occur during the first three weeks postpartum. The earlier in lactation disease occurs, the longer the legacy effects from that disease can impact cow health and performance. Dr. Santos describes an experiment in beef cattle evaluating how an inflammatory response impacts nutrient partitioning away from performance. Early lactation morbidity not only makes a cow not want to eat, it also may shift nutrients away from production toward survival, resulting in fewer nutrients available for milk production and reproduction. Dr. Santos describes a series of experiments evaluating the impact of early lactation disease diagnosis on reproductive performance. Dr. Santos' second take-home message is to stimulate dry matter intake and minimize disease in the early lactation period. (22:21) How can we formulate diets that will improve reproduction? First, we should formulate diets that reduce the risk of disease. Then we should incorporate nutrients that are known to improve reproduction in cows. Dr. Santos describes how supplementation with rumen-protected choline decreases triglyceride accumulation in the liver and improves milk yield. He also details the mechanisms of using acidogenic diets to reduce hypocalcemia. He recommends not using these diets for heifers and feeding them for around 21 days to cows rather than the entire dry period. Dr. Santos feels that forage quality has been neglected in the transition period and details how improved fiber digestibility during the transition period can have longer-term impacts. Lastly, he recommends feeding 1-1.5% supplemental fat in early lactation diets for improved reproduction and milk yield without negative impacts on body condition. In closing, Dr. Santos presents a summary of diet formulation recommendations for transition cows.  (34:13) Dr. Santos leads an engaged question-and-answer session with the webinar audience. (51:11) Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.   If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt. 

Focus Issue on Diabetes and Metabolic Disorders

Dr. Ahmed is the Director of Research and Operations for METAVOMetavo is a first of its kind high concentration of AvoB, the natural compound found in avocados which restores and promotes true metabolic health.With a doctoral degree in Food Science from the University of Guelph, Dr. Ahmed has emerged as a trailblazer in the field of metabolic health and nutritional biochemistry. He hit the scene with a groundbreaking doctoral thesis titled "Clinical Development of Avocado-Derived Lipids as Modulators of Fatty Acid Oxidation for the Treatment and Management of Metabolic Disorders." This seminal work laid the foundation for the development of innovative solutions that form the core of Metavo's product offerings. Currently serving as the Director of Research at SP Nutraceuticals, Dr. Ahmed has been pivotal in the product development and successful launch of Metavo, the flagship natural health product that leverages the benefits of avocado for metabolic well-being. TNoteworthy is Dr. Ahmed's role as the study director for the first-in-human clinical trial of Metavo and his current role in conducting further clinical research on Metavo.Join Ken and Eric on the GCP as they learn from Dr. Ahmed all bout the natural ways to boost metabolic health with METAVO!https://www.metavo.com/

Send us a textResources for the Community:___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55___________________________________________________________________The Provider Spotlight is a new bonus series of shorter episodes featuring doctors and specialists from past sessions—think of it as 'doctor shorts.' With over 25k scripts for Zepbound written weekly, many new subscribers haven't seen our earlier episodes, which helps them catch up quickly. Thanks for your support!On July 17th of 2023 Dr Alexandra set down with the Plus Sidez and discussed the affects of Metabolic Disorders & Mounjaro/GLP1 TreatmentsBIODr. Alexandra Sowa is the CEO and founder of SoWell Health, a consumer metabolic healthcare company. SoWell supports patients at every point of their health and weight loss journey through at-home laboratory testing kits, evidence-based nutraceuticals, and scalable telehealth access to medical weight management.  Dr. Sowa is dual-board-certified physician of internal and obesity medicine and clinical instructor of medicine at NYU Langone. Dr. Sowa has served as a health expert for national media outlets and print publications like SiriusXM, CBS News, NPR, the New York Times, U.S. News, World Report, and more.You them find us at  www.getsowell.com______________________________________________________________________⭐️Mounjaro Stanley⭐️griffintumblerco.Etsy.comUse code PODCAST10 for $ OFF______________________________________________________________________Join this channel to get access to perks:   / @theplussidez______________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide  #GLP1 #Obesity #zepbound #wegovy  Support the showKim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

Send us a textWhat if we told you that your liver plays a more critical role in your health than you ever imagined? This episode of MedEvidence promises to uncover the essential functions of the liver, from detoxification to immune support, and explain why maintaining liver health is pivotal. Dr. Nikhil Kapila dissects the complexities of fatty liver disease, now rebranded as metabolic dysfunction-associated steatotic liver disease (MASLD), and its alarming connections to metabolic disorders such as obesity, diabetes, and high cholesterol. We'll also explore the broader spectrum of liver diseases, including alcohol-related liver disease, viral hepatitis, and rare conditions like primary biliary cholangitis and autoimmune hepatitis. Get ready to learn about groundbreaking treatments and gain insight into the rising prevalence of MASLD as a leading cause of liver disease and liver transplantation.Three Key Takeaways:Understanding Fatty Liver DiseaseClinical Trials for Fatty Liver DiseaseQ&A from the publicRecording Date: August 15, 2024Be a part of advancing science by participating in clinical research.Listen on SpotifyListen on AppleWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInWant to learn more checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

In this enlightening episode, we are joined by Dr. Stephanie Venn Watson, co-founder of Fatty15.com and DiscoverC15.com, to explore the groundbreaking benefits of C15:0, an essential fatty acid that has been overlooked for decades. Dr. Venn Watson shares her pioneering research on C15:0 and its potential to revolutionize the way we approach health and disease. Key Topics Discussed: 1.Introduction to C15:0 Understanding what C15:0 is and why it's considered an essential fatty acid. The journey from discovery to developing a pure C15:0 supplement   2. Cellular Fragility Syndrome What is cellular fragility syndrome, and how does it impact aging and overall health? How C15:0 strengthens cell membranes, promoting resilience and longevity. 3. Non-Alcoholic Fatty Liver Disease (NAFLD) The growing prevalence of NAFLD and its impact on liver health. Insights into how C15:0 can help manage and potentially reverse the effects of NAFLD. 4.Metabolic Disorders and C15:0 The role of C15:0 in regulating metabolism. How C15:0 can be used to support metabolic health and prevent disorders such as obesity and insulin resistance. 5. Cardiovascular Health Exploring the cardiovascular benefits of C15:0, including its effects on cholesterol levels and heart function. The potential of C15:0 as a natural way to support cardiovascular health and reduce the risk of heart disease. 6.C15:0 and Diabetes The connection between C15:0 and glucose metabolism. How C15:0 can play a role in managing diabetes and reducing the risk of related complications. 7. Aging and Longevity The role of C15:0 in promoting healthy aging. How C15:0 supports longevity by reducing inflammation, oxidative stress, and cellular damage. 8. Practical Uses and Dosage Recommended dosages of C15:0 for different health conditions. How to incorporate C15:0 into your daily routine for optimal benefits. BIO Dr. Stephanie Venn Watson is a renowned scientist and co-founder of Fatty15.com and DiscoverC15.com. With years of research and dedication, she has brought to light the critical role of C15:0 in human health, offering new hope for managing and preventing a wide range of diseases. Her work has been published in numerous scientific journals, and she continues to be a leading voice in the field of metabolic and cardiovascular health. Resources Mentioned: Visit Fatty15.com and DiscoverC15.com to learn more about C15:0 and its health benefits. Scientific articles and studies referenced in this episode. Join the Conversation: Have questions or want to share your thoughts on this episode? Connect with us on social media or leave a comment on our website. Subscribe & Review: If you enjoyed this episode, please subscribe to our podcast and leave us a review! Your feedback helps us continue to bring you the latest insights in health and wellness.   Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with:  Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen,  intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals  Nutristat Omega 3 to 6 status and more  Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the  challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa    Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission.  Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to  Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to  https://www.buymeacoffee.com/LisaT to donate $3   Lisa's Anti-Aging and Longevity Supplements  Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.  This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.   Subscribe to our popular Youtube channel  with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube   Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge"  Check them all out at  https://shop.lisatamati.com/collections/books   Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here:    Use code "tamati" at checkout to get a 10% discount on any of their devices.   Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38   Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off     Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts.  To pushing the limits, Lisa and team

Dr. Allison Marshall and Dr. John Langlois have Dr. Wynnie Angus as a guest, and the three vets discuss various approaches to many metabolic disorders and how horses respond when they have multiple issues, in medical-speak co-morbidities.Link to Sound File for Sight Impaired Click HereYour Hosts: Dr. Allison Marshall and John LangloisSponsored by: Chi UniversityGuest: Dr. Wynnie Angus, Woodside Equine ClinicFollow Horse Radio Network on Twitter or follow Horses In The Morning on FacebookAdditional support for this podcast provided by Listeners Like You

Dr. Allison Marshall and Dr. John Langlois have Dr. Wynnie Angus as a guest, and the three vets discuss various approaches to many metabolic disorders and how horses respond when they have multiple issues, in medical-speak co-morbidities.Link to Sound File for Sight Impaired Click HereYour Hosts: Dr. Allison Marshall and John LangloisSponsored by: Chi UniversityGuest: Dr. Wynnie Angus, Woodside Equine ClinicFollow Horse Radio Network on Twitter or follow Horses In The Morning on FacebookAdditional support for this podcast provided by Listeners Like You

Guang Qu, Co-Founder of NGGT Corporation is focused on developing gene therapy products using dual functional vector strategies. Guang highlights the importance of distinguishing between recessive and dominant mutations in rare diseases and explains how their approach differs from other gene therapy approaches. The two leading indications caused by a gene mutation that NGGT is working on are Bietti's Crystalline Dystrophy (BCD), a rare ocular disease, and phenylketonuria (PKU), a metabolic disease.   Guang explains, "For our strategies and our product development strategies, I think we are leveraging our experience in the gene therapy field. Later, I will talk more about myself, Dr. Lixin Jiang, and our team. The other thing we are leveraging is our fully integrated team in gene therapy product development, which involves R&D, research and development, CGMP manufacturers, from tox development and clinical regulatory functions and the medical teams. So with all of the teams we built up in the last couple of years, we're in very good positions in developing our gene therapy products." "So, of the two currently leading indications, one is involved in ocular disease, what we call the BCD, Bietti's Crystalline Dystrophy. This disease is caused by a gene mutation. The gene mutation causes lipid metabolic problems. The particular gene is called the CYP4V2 gene. The mutation directly leads to the lipid metabolic process being interrupted. Therefore, lipids are precipitated in the different ocular cells, such as the cornea and the retina. That's most of the disease cell layers affected."  #AAV #GeneEditing #GeneTherapy #PKU #BCD Listen to the podcast here

Guang Qu, Co-Founder of NGGT Corporation is focused on developing gene therapy products using dual functional vector strategies. Guang highlights the importance of distinguishing between recessive and dominant mutations in rare diseases and explains how their approach differs from other gene therapy approaches. The two leading indications caused by a gene mutation that NGGT is working on are Bietti's Crystalline Dystrophy (BCD), a rare ocular disease, and phenylketonuria (PKU), a metabolic disease.   Guang explains, "For our strategies and our product development strategies, I think we are leveraging our experience in the gene therapy field. Later, I will talk more about myself, Dr. Lixin Jiang, and our team. The other thing we are leveraging is our fully integrated team in gene therapy product development, which involves R&D, research and development, CGMP manufacturers, from tox development and clinical regulatory functions and the medical teams. So with all of the teams we built up in the last couple of years, we're in very good positions in developing our gene therapy products." "So, of the two currently leading indications, one is involved in ocular disease, what we call the BCD, Bietti's Crystalline Dystrophy. This disease is caused by a gene mutation. The gene mutation causes lipid metabolic problems. The particular gene is called the CYP4V2 gene. The mutation directly leads to the lipid metabolic process being interrupted. Therefore, lipids are precipitated in the different ocular cells, such as the cornea and the retina. That's most of the disease cell layers affected."  #AAV #GeneEditing #GeneTherapy #PKU #BCD Download the transcript here

Dr. Cate Shanahan is a renowned nutrition expert and author of "Deep Nutrition" and "Dark Calories." In this episode she delves into the hidden truths behind modern nutrition and the profound impact of seed oils on our health. With over a decade of research and a passion for uncovering the root causes of disease, Dr. Cate provides invaluable insights into how our diet influences metabolic health and chronic diseases. Tune in as she shares her journey, discoveries, and actionable advice for achieving optimal health through better nutrition.Key topics discussed:- Impact of seed oils on metabolic health and chronic diseases.- Oxidative stress as the root cause of health issues.- History and rise of vegetable oils in the food supply.- Differences between fats and dangers of polyunsaturated fats.- Practical dietary changes to reduce oxidative stress.Timestamps:(00:00) Nutrition Expert Discusses Root Causes(07:53) The Role of Vegetable Oils(23:16) Potential Risks of Rapid Weight Loss(27:46) The Impact of Dietary Choices*** LINKS***Check out our Newsletter - Food for Thought - to dramatically improve your health this year!Join The Meat Mafia community Telegram group for daily conversations to keep up with what's happening between episodes of the show.Connect with Dr. Cate:WebsiteBooksTwitterInstagramYouTubeConnect with Meat Mafia:Instagram - Meat MafiaTwitter - Meat MafiaYouTube - Meat MafiaConnect with Noble Protein:Website - Noble ProteinTwitter - Noble ProteinInstagram - Noble ProteinAFFILIATESLMNT - Electrolyte salts to supplement minerals on low-carb dietThe Carnivore Bar - Use Code 'MEATMAFIA' for 10% OFF - Delicious & convenient Pemmican BarPerennial Pastures - Use CODE 'MEATMAFIA' 10% OFF - Regeneratively raised, grass-fed & grass-finished beef from California & MontanaFarrow Skincare - Use CODE 'MEATMAFIA' at checkout for 20% OFFHeart & Soil - CODE ‘MEATMAFIA' for 10% OFF - enhanced nutrition to replace daily vitamins!Carnivore Snax - Use CODE 'MEATMAFIA' Crispy, airy meat chips that melt in your mouth. Regeneratively raised in the USA.Pluck Seasoning - 15% OFF - Nutrient-dense seasoning with INSANE flavor! Use CODE: MEATMAFIAWe Feed Raw 25% OFF your first order - ancestrally consistent food for your dog! Use CODE 'MEATMAFIA'Fond Bone Broth - 15% OFF - REAL bone broth with HIGH-QUALITY ingredients! It's a daily product for us! Use CODE: MAFIA

Focus Issue on Valvular Heart Disease, Diabetes, Metabolic Disorders, and Hypertension

This episode will help you better prepare for and manage children with inborn errors of metabolism in the Emergency Department. Consider it a supplement to what you remember from Biochemistry and the instructions on the family's laminated care plan sheet. My special guest podcaster, Emily Groopman, is an actual Pediatric Geneticist in training and we […]

Understanding the thyroid is one of the most important things women can do, especially in perimenopause and menopause. There are so many misconceptions surrounding the thyroid, including appropriate testing, supplements, medications, diet, lifestyle, the different causes, and contributing factors to thyroid dysfunction. The guidance people receive from their healthcare providers often leave them confused, and often they still don't feel well and symptoms persist despite being on medication to treat their thyroid disorder. Dr. Mazza is triple board-certified in endocrinology, internal medicine, and anti-aging and regenerative medicine. She is the author of the recently released book, “Thyroid Talk,” and the owner of the Metabolic Center for Wellness in Florida.  She uses a unique, integrative approach to managing and treating thyroid and other metabolic disorders, and she is only physician in Central Florida who can perform a safe, non-surgical, minimally invasive procedure for thyroid nodules!  In this conversation, Dr. Mazza dispels thyroid myths, discusses needed testing to appropriately evaluate thyroid function, answers the most commonly asked questions about Hashimoto's disease, explains why autoimmune diseases increase with age in women, new research on selenium, why women in perimenopause and menopause struggle with weight loss, use of GLP-1 medications, and she provides actionable steps one can take to improve their thyroid and overall health. Purchase Dr. Mazza's book here.Subscribe to the podcast on Apple or your favorite podcast platform: https://podcasts.apple.com/us/podcast/midlife-wellness-np/id1517262867 Subscribe to my YouTube Channel: https://www.youtube.com/channel/UCP1MLJvcxegZ7Bv7---PUEQFollow me: https://linktr.ee/KimHeifnerWellnessSupport the showFollow me:FacebookFacebook groupInstagramTwitterLinkedInPlease subscribe to my YouTube channel!

In this episode of the Iron Sights podcast, Stephen, Cece, and I challenge the notion that lowering LDL cholesterol is the primary key to preventing heart disease. Amidst the ongoing debates on diets—carnivore, keto, low carb, and plant-based—we get into interesting studies like ones involving Oreos, revealing surprising insights about cholesterol. We break down the basics, discussing what cholesterol does in the body, the effects of drugs, and more.Timestamps00:00 Intro03:10 Topic: Blood Test And Cholesterol06:19 Do Oreos Cookies Lower Your Cholesterol?10:01 How Your Body Deals With Cholesterol13:42 The Number One Killer In The US15:48 What Does Your Body Need Cholesterol For?17:24 Triglycerides19:56 Statin Medications25:26 The Lipid Energy Theory37:06 The Side Effects Of Statins48:32 Increasing Fiber In Your Diet To Reduce Your LDL Levels58:38 Why Is It Important To Take Full Blood Panels?Red Dot Fitness Training Programs:https://www.rdftrainonline.comOnline Membership (Full Access To All Programs & Virtual Coaching):https://www.reddotfitness.net/online-membershipVirtual Coaching:https://www.reddotfitness.net/virtual-coachingSelf-Guided Programs:https://www.reddotfitness.net/Self-Guided-Programs1Connect With Us:Website - https://ironsightspodcast.com/Instagram - https://www.instagram.com/ironsightspodcast/Facebook - https://www.facebook.com/ironsightspodcast/

Bill's Bio: Dr. Bill Cromwell, with over three decades of expertise, has specialized in diagnosing and managing lipid and metabolic disorders since 1990. His extensive career encompasses roles as a Medical Director/Division Chief, spanning 14 years, in Lipoprotein and Metabolic Disorders at various institutions. For six years, he served as Chief Medical Officer at LipoScience, a pioneering lipoprotein diagnostic company. Furthermore, Dr. Cromwell spent four years as Strategic Director/ Discipline Director of Cardiovascular Disease at LabCorp. His passion lies in developing strategies and tools that accurately assess individual risk, establish tailored goals, and monitor therapy responses to deliver patient-specific care, which is the core mission of Precision Health Reports. Want a discount on your Precision Health Report? Visit their website and enter the discount code below. Transform your health with information: http://www.precisionhealthreports.com Discount code (20%): NEUTRALPOSITION Sponsored By: Diesel Jack Media: https://dieseljackmedia.com/ Warrior Rising: http://www.warriorrising.org Empower Employ: https://www.empoweremploy.us/s/appointments The Neutral Position is Hosted by Nick Palmisciano Nick Palmisciano is a New York Times Bestselling Author, Filmmaker, Founding Board Member of the international rescue non-profit Save Our Allies, and the CEO of the full-service marketing agency Diesel Jack Media. Nick is a Graduate of the United States Military Academy at West Point and received his MBA from Duke University. He received the prestigious “Entrepreneur of the Year” award from the Entrepreneur Organization in 2015 and is a proud recipient of the U.S. Army Ranger Tab. You can find this episode wherever podcasts are streamed:  Itunes: https://apple.co/3MrPlNE Spotify: http://bit.ly/43dBUGS Facebook: https://bit.ly/3mf56wD Instagram: https://bit.ly/3ZRY7Hq TikTok: http://bit.ly/3A0bhrL Nick Palmisciano Facebook: https://bit.ly/43h4erR Twitter: https://bit.ly/40SKQ2N IG: https://bit.ly/40WADlZ Diesel Jack Media Facebook: https://bit.ly/3UnGvlJ Instagram: https://bit.ly/43h4o2r

In this episode, we dissect the intricate dynamics of hidradenitis suppurativa, a chronic skin disease significantly impacting patients' lives. I have the pleasure of conversing with Dr. Iltefat Hamzavi, a leading dermatologist and researcher in the field. Together, we explore the intersections of this complex condition with metabolic disorders, as well as delve into its diagnosis, treatment options, and the roles genetics and hormones play. Please SUBSCRIBE to the Derm Club Podcast wherever you like to listen whether on YouTube, Apple, or Spotify. Together, let's explore the fascinating secrets of dermatology and skincare. To learn more about HS: https://www.hannahkopelman.com/blog/hidradenitis-suppurativa-and-metabolic-disorder/ Connect with me across Social: Twitter: https://twitter.com/drhankopelman Instagram: https://www.instagram.com/doctor.han/ TikTok: https://www.tiktok.com/@drhankopelman Blog: https://www.hannahkopelman.com/blog/ The content of this podcast is for entertainment and educational purposes only. This content is not meant to be a substitute for medical advice or treatment for any medical condition. --- Send in a voice message: https://podcasters.spotify.com/pod/show/hannah-kopelman/message

Our community guest today is Lisa. She bravely shares her health struggles with PCOS and insulin resistance. Lisa's metabolic health issues likely lead to her obesity and she explains the positive effects Mounjaro has had on her health as well as weight. Our medical specialist is Dr. Alexandra Sowa, the founder of SoWell Health and an obesity specialist. Dr. Sowa helps us further understand the effects GLP1 medications like Mounjaro have on health, not just weight to help validate Lisa's health experience.  Follow Lisa on TikTok @Lisa_pnwFollow Dr. Sowa on TikTok  and Instagram @alexandrasowamd Bio Dr. Alexandra Sowa is the CEO and founder of SoWell Health, a consumer metabolic healthcare company. SoWell supports patients at every point of their health and weight loss journey through at-home laboratory testing kits, evidence-based nutraceuticals, and scalable telehealth access to medical weight management.  Dr. Sowa is dual-board-certified physician of internal and obesity medicine and clinical instructor of medicine at NYU Langone. Dr. Sowa has served as a health expert for national media outlets and print publications like SiriusXM, CBS News, NPR, the New York Times, U.S. News, World Report, and more. You them find us at  www.getsowell.comSupport the showKim Carlos @DMFKimonMounjaro on TikTokJernine Trott @TheeJernine on TikTokKat Carter @KatCarter7 on TikTokLydia Roberts @mounjaro_GLP_Help on TikTok

Today we learn about Ayurvedic medicine. What is it? How does it work?Learn from our guest Om who is a former Pharmaceutical Medical Science liaison before he decided to practice and teach Ayurvedic medicine.Om Received his Ayurvedic Wellness Counseling training from Kerala Ayurveda Academy (Currently at KAA school for Ayurveda Wellness Practitioner Program- 2021- 2023) and is a Certified Health Coach from the Institute of Integrative Health, NYHaving vast experience in healthcare and pharmaceuticals field for more than three decades, Om understands the limitations of Western Medicine and is able to fill these gaps by integrating holistic and natural remedies with the current healthcare practices.Om is currently practicing at an established Ayurveda and Yoga Practice in Rockville, MD- www.vedichealth.org since last four years. Om's life purpose is to help individuals maintain and/or regain their optimal health through Principles of Ayurveda and by contributing to the community what constitutes a healthy and happy society.Om has an expertise in the management of Metabolic Disorders (including obesity), Women's/Men's Health, Gut Health and General health utilizing Ancient Ayurvedic Diet, Herbs and Lifestyle Principles.Om can be reached at https://www.vedichealth.org-----------------------------------------------------Remember that if you do have a rheumatologic issues, we can help you and you can aim to remission (with treatment).Enjoy and share the episode if you liked it. If you are in need of a rheumatologist in Colorado, look no further. To schedule an appointment, please email at info@unabridgedMD.com or call us at 303-731-4006#rheumatologist #Denver #autoimmunedisease#RheumatologyClinic #JointPain #Arthritis #inflammatory #podcastIf you live in Colorado and are looking for a rheumatologist to help you achieve disease remission, email or contact us at UnabridgedMD.com. We are the first direct care rheumatology in Colorado and can see you within a week!

Brett Lloyd is a returning guest on our show! Be sure to check out his first appearance on episode 123 of Boundless Body Radio, which was a special episode recorded with Dr. Nick Norwitz, and Dr. Chris Palmer, the bestselling author of the book Brain Energy, released in 2022!! Brett Lloyd is a remarkable individual who has dedicated his life to helping people who struggle with anxiety, depression, and other mood-related conditions. Brett himself had major depression, chronic anxiety, and insomnia for 43 years, for which he took psychiatric medications for 23 years. In 2015, he weighed 289 pounds and was on seven different psych meds. He then tried a low-carb diet and eventually shifted to a carnivore lifestyle that healed him entirely. Over three years, he lost 94 pounds and became pharmaceutical-free. He believes that this approach to lifestyle has been nothing short of miraculous, and he has made it his mission to help others overcome their challenges and improve their overall well-being, through the Revero platform where we are both certified carnivore coaches. Find Brett at- IG-@thankful.carnivoreTW- @StickmanBleedinFind Boundless Body at- myboundlessbody.com Book a session with us here!

Welcome to The Tactical Living Podcast, the show that explores the nexus of tactical skills and personal growth. In today's episode, Coach Ashlie Walton and Detective Walton delve into the groundbreaking work of Chris Palmer, a Harvard psychologist, and his illuminating book, "Brain Energy." Join us as we examine Palmer's research, which challenges conventional notions of mental disorders, asserting that they are, in fact, metabolic disorders of the brain. Get ready for a thought-provoking exploration of how understanding the brain's metabolic processes can reshape our approach to mental health.   Episode Highlights:   Introducing Chris Palmer and "Brain Energy":   ·       A brief overview of Chris Palmer's background and his influential work as a Harvard psychologist. ·       An introduction to his book, "Brain Energy," which explores the connection between metabolic processes and mental disorders. ·       Highlighting the paradigm shift Palmer's research brings to our understanding of mental health.   The Metabolic Perspective on Mental Disorders:   ·       Discussing Palmer's assertion that mental disorders should be viewed as metabolic disorders of the brain. ·       Exploring the link between energy metabolism and neurotransmitter imbalances in mental health conditions. ·       How understanding metabolic dysregulation can offer new insights into treatment approaches.   Implications for Treatment and Prevention:   ·       Examining how the metabolic perspective can influence the development of more effective treatments for mental disorders. ·       Discussing the potential impact of nutritional interventions, exercise, and lifestyle modifications on mental well-being. ·       Exploring the importance of a holistic approach that addresses both metabolic and psychological aspects.   Promoting Mental Health and Well-being:   ·       How the insights from Palmer's work can inform strategies for maintaining and enhancing mental health. ·       Discussing the role of nutrition, sleep, exercise, and stress management in supporting optimal brain metabolism. ·       Encouraging listeners to take proactive steps towards holistic well-being.   In this episode of The Tactical Living Podcast, we've delved into the pioneering research of Chris Palmer and his book, "Brain Energy." By reframing mental disorders as metabolic disorders of the brain, Palmer offers us a fresh perspective on mental health and potential avenues for more effective treatment and prevention. Remember, nurturing our brain's energy metabolism through holistic lifestyle choices can play a vital role in promoting mental well-being.   Stay tuned for our next episode, where we'll continue to explore insights at the intersection of tactical skills and personal growth to empower you on your journey of self-improvement.   ⩥ PLEASE SUBSCRIBE TO OUR YOUTUBE CHANNEL ⩤ https://bi3xbvVont.ly/   CLICK HERE for our best-selling products: https://amzn.to/3xaG3xw and https://rdbl.co/3DIQVUC   CLICK HERE to join our free Police, Fire, Military and Families Facebook Group: https://bit.ly/38w2e7r   Check out our website and learn more about how you can work with LEO Warriors by going to: https://www.leowarriors.com/   Like what you hear? We are honored. Drop a review and subscribe to our show.    The Tactical Living Podcast is owned by LEO Warriors, LLC. None of the content presented may be copied, repurposed or used without the owner's prior consent.   For PR, speaking requests and other networking opportunities, contact LEO Warriors:   EMAIL: ashliewalton555@gmail.com.   ADDRESS: P.O. Box 400115 Hesperia, Ca. 92340   ASHLIE'S FACEBOOK: https://www.facebook.com/police.fire.lawenforcement   ➤➤➤➤➤➤➤➤➤➤➤➤➤➤➤➤➤➤ This episode is NOT sponsored. Some product links are affiliate links which means if you buy something by clicking on one of our links, we'll receive a small commission.  

Cancer will affect nearly everyone in our country! Your body forms cancers for a reason, know why cancer forms and you will know the solutions! Don't miss this life changing episode! 

Are mental disorders actually metabolic disorders of the brain? Psychiatrist and Harvard professor Dr. Chris Palmer helps us understand the connection between mental health and physical health and shares how his take on the ketogenic diet can treat mental health issues through healing metabolism.In this episode we cover:0:03:51 – Unified Theory of Mental Illness0:12:36 – Taxonomy of Mental Disorders0:14:17 – Statistics0:16:30 – Comorbidities0:22:57 – Causes0:26:31 – Treatment-Resistant Disorders0:28:01 – Genes0:34:21 – Epigenetics0:44:06 – Mitochondria0:49:31 – Metabolic Disorders of the Brain0:51:01 – Mind Body Connection0:54:26 – Hormones1:06:10 – Compromised Metabolism1:10:07 – Ketogenic Diet1:18:49 – Processed Foods1:26:58 – Gut Health1:29:52 – Autophagy1:35:08 – Intermittent FastingLearn more about Commune and check out all our health, nutrition, and functional medicine courses free for 14 days at onecommune.com/trial This podcast is supported by:Timeline NutritionTimeline Nutrition is pioneering a new approach to longevity, one that stands on a decade of scientific discovery to unlock the power within your cells. Your body is an energy generating machine, Timeline makes it more powerful. Use code commune to get 10% off at timelinenutrition.com/commune.Thrive MarketJoin Thrive Market today and get a FREE $80 in free groceries when you go to thrivemarket.com/communeLivOn LabsDiscover why Jeff Krasno, Schuyler Grant, and people who know wellness are ditching pills, powders, and gummies for this powerful, nutrient-packed goo. GET FREE SAMPLES WITH ANY PURCHASE livonlabs.com/commune Kyolic Prevention is the best way to protect your heart health. In addition to maintaining a healthy diet,exercise and good sleep patterns, you can include one of the best-researched natural herbal supplements to your routine, Kyolic Aged Garlic Extract. Request a sample at Kyolic.com/sample-request. Use promo code “Commune”.IONCommune Podcast Listeners can save 15% on GUT Support. Go to: https://intelligenceofnature.com/pages/commune

In this bonus, Gabby follows up on her conversation with Dr. Chris Palmer about lifestyle changes we can make to better our metabolic disorders. Questions explored: What lifestyle changes have you made this past year? Are there habits you kicked or picked up this year that you've maintained for the better? Connect with Gabby @gabbyreece | Linktree For show notes and past guests, please visit gabriellereece.com/podcast The Gabby Reece Show talks to top experts with the goal of extracting the best information you will need to navigate the universe of health, fitness, relationships, parenting, and business. Gabby keeps it simple but gets to the heart of the conversation with the hopes of providing you with realistic takeaways. Learn more about your ad choices. Visit megaphone.fm/adchoices

Huberman Lab Podcast Notes Key Takeaways Nutrition and mental health interact intimately and even causally in some casesProcessed foods rich in fat, carbohydrates, and sugar are the worst for metabolic health and mental healthInsulin resistance is impaired in people with chronic mental disordersA ketogenic diet has shown beneficial effects in the treatment of chronic depression, PTSD, Alzheimer's, alcohol use disorder, bipolar disorder, schizophrenia, epilepsyThe beauty of the ketogenic diet for intervention is you can measure with objective biomarkers“Once you understand the science of mitochondria, you can actually connect all the dots of the mental health puzzle.” – Dr. Chris PalmerCalorie restriction, ketogenic diet, and carbohydrate restriction are inducing metabolic changes in the brain and body that can be beneficial to brain health – it's not just about villainizing sugar or carbohydrates aloneJust like medication, dose the diet: for some people, symptoms can be reduced without fully being on a ketogenic diet; just cutting highly processed foods rich in carbohydrates, fat, and sugar is sufficientThe obesity epidemic is really a mystery though we want to believe it's diet; it's not as simple as energy balance or food – we had junk food and highly processed diets in the 70s – it's likely mitochondrial health deficits Sleep disruption, stress, trauma, drug and alcohol use, tobacco, and THC impair mitochondria and mitochondrial dysfunction“I see obesity as a symptom of metabolic derangement in the body or brain…and if we're really going to get anywhere we need to identify what is causing metabolic derangement.” – Dr. Chris PalmerExogenous ketones or supplementing with ketones while on a standard diet isn't enough The ketogenic diet isn't just about ketones, people on the diet are also lowering glucose levels, improving insulin signaling, ramping up mitochondrial biogenesis (particularly in the liver), gut microbiome changes, hormones are repaired, etc.  Read the full notes @ podcastnotes.orgMy guest this episode is Chris Palmer, M.D., a board-certified psychiatrist and assistant professor of psychiatry at Harvard Medical School. He explains the important connection between nutrition, metabolism and mental health and his pioneering work using the ketogenic diet to successfully treat patients with various mental illnesses, including depression and schizophrenia. Dr. Palmer explains how the ketogenic diet is an evidenced-based treatment for epilepsy, mimics the fasted state and can offset the cognitive decline in Alzheimer's. He describes the key roles of mitochondria in mental health, how certain conditions likely arise from mitochondrial dysfunction, and how low-carbohydrate diets increase mitochondrial turnover to improve mental health. He also explains how low-carbohydrate diets positively impact the gut microbiome and weight loss, important risk factors for mitochondrial health such as marijuana and alcohol, and the best way to increase circulating ketones depending on individual needs. We also cover how a ketogenic diet impacts mood, sleep, and fertility. Dr. Palmer's work stands as a revolutionary approach to mental health and disease that, given the prevalence of mental health challenges, should be of interest to people of all backgrounds and ages. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Chris Palmer, Mental Health & Metabolic Disorders (00:03:25) Thesis, Eight Sleep, ROKA (00:07:18) Nutrition & Mental Health (00:20:43) Low-Carb Diets & Anti-Depression, Fasting, Ketosis (00:27:52) Schizophrenia, Depression & Ketogenic Diet (00:34:32) AG1 (Athletic Greens) (00:35:38) Psychiatric Mediations, Diet Adherence (00:42:35) Highly Processed Foods, Ketones & Mental Health Benefits (00:46:51) Ketogenic Diet & Epilepsy Treatment (00:56:10) Ketogenic Diet & Mitochondria Health (00:57:05) Nutrition & Benefits for Neurologic/Psychiatric Disorders (01:05:44) Mitochondrial Function & Mental Health (01:15:12) InsideTracker (01:16:23) Mitophagy, Mitochondrial Dysfunction, Aging & Diet (01:25:09) Neurons, Mitochondria & Blood Glucose (01:31:54) Obesity, Ketogenic Diet & Mitochondria (01:40:00) Mitochondrial Function: Inheritance, Risk Factors, Marijuana  (01:46:34) Alcohol & Ketogenic Diet (01:55:21) Brain Imaging, Alzheimer's Disease & Ketones (02:01:05) Exogenous (Liquid) Ketones vs. Ketogenic Diet (02:06:27) Neuronal Damage, Ketones & Glucose  (02:10:16) Alzheimer's Disease, Age-Related Cognitive Decline & Ketogenic Diet (02:23:45) Ketogenic Diet & Weight Loss (02:35:47) Ketogenic Diet & Fasting, Hypomania, Sleep (02:46:37) Low Carbohydrate Diets, Menstrual Cycles, Fertility (02:52:23) Obesity Epidemic, Semaglutide & GLP-1 Medications  (03:01:01) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Social Media Disclaimer Title Card Photo Credit: Mike Blabac

My guest this episode is Chris Palmer, M.D., a board-certified psychiatrist and assistant professor of psychiatry at Harvard Medical School. He explains the important connection between nutrition, metabolism and mental health and his pioneering work using the ketogenic diet to successfully treat patients with various mental illnesses, including depression and schizophrenia. Dr. Palmer explains how the ketogenic diet is an evidenced-based treatment for epilepsy, mimics the fasted state and can offset the cognitive decline in Alzheimer's. He describes the key roles of mitochondria in mental health, how certain conditions likely arise from mitochondrial dysfunction, and how low-carbohydrate diets increase mitochondrial turnover to improve mental health. He also explains how low-carbohydrate diets positively impact the gut microbiome and weight loss, important risk factors for mitochondrial health such as marijuana and alcohol, and the best way to increase circulating ketones depending on individual needs. We also cover how a ketogenic diet impacts mood, sleep, and fertility. Dr. Palmer's work stands as a revolutionary approach to mental health and disease that, given the prevalence of mental health challenges, should be of interest to people of all backgrounds and ages. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Chris Palmer, Mental Health & Metabolic Disorders (00:03:25) Thesis, Eight Sleep, ROKA (00:07:18) Nutrition & Mental Health (00:20:43) Low-Carb Diets & Anti-Depression, Fasting, Ketosis (00:27:52) Schizophrenia, Depression & Ketogenic Diet (00:34:32) AG1 (Athletic Greens) (00:35:38) Psychiatric Mediations, Diet Adherence (00:42:35) Highly Processed Foods, Ketones & Mental Health Benefits (00:46:51) Ketogenic Diet & Epilepsy Treatment (00:56:10) Ketogenic Diet & Mitochondria Health (00:57:05) Nutrition & Benefits for Neurologic/Psychiatric Disorders (01:05:44) Mitochondrial Function & Mental Health (01:15:12) InsideTracker (01:16:23) Mitophagy, Mitochondrial Dysfunction, Aging & Diet (01:25:09) Neurons, Mitochondria & Blood Glucose (01:31:54) Obesity, Ketogenic Diet & Mitochondria (01:40:00) Mitochondrial Function: Inheritance, Risk Factors, Marijuana  (01:46:34) Alcohol & Ketogenic Diet (01:55:21) Brain Imaging, Alzheimer's Disease & Ketones (02:01:05) Exogenous (Liquid) Ketones vs. Ketogenic Diet (02:06:27) Neuronal Damage, Ketones & Glucose  (02:10:16) Alzheimer's Disease, Age-Related Cognitive Decline & Ketogenic Diet (02:23:45) Ketogenic Diet & Weight Loss (02:35:47) Ketogenic Diet & Fasting, Hypomania, Sleep (02:46:37) Low Carbohydrate Diets, Menstrual Cycles, Fertility (02:52:23) Obesity Epidemic, Semaglutide & GLP-1 Medications  (03:01:01) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Social Media Disclaimer Title Card Photo Credit: Mike Blabac

Can we alter neonatal gut microbiome to prevent spondyloarthritis? Dr Chao discusses Abstract 0868 at the ACR22 Convergence meeting.  Abstract 0868: Spondyloarthritis and Neonatal Factors Affecting the Gut Microbiome JAK vs TNF inhibitor Infections in RA Dr. David Liew discusses abstract 0302 at ACR22 Convergence. Abstract 0302: Risk of Infections Between JAK Inhibitors and TNF Inhibitors Among Patients with Rheumatoid Arthritis Opioid and Neuropathic Use After Initiating btsDMARDs in RA Dr. Julian Segan discusses Abstract 0925 at the ACR22 Convergence meeting. The Dietary Intervention in PsA (DIPSA) StudyDr. Patricia Harkins talks with Professor Lihi Eder about abstract 1007 at the ACR22 Convergence meeting.  Abstract 1007: Metabolic Disorders and Abnormal Dietary Patterns and Their Association with Psoriatic Arthritis Activity: The Dietary Intervention in PsA (DIPSA) Study Treatment Considerations in Axial Spondyloarthritis Dr. Lianne Gensler discusses treatment considerations in Axial SpA. Abstract 0402: Opioid Use and Healthcare Utilization in Adults with PsA and AS Abstract 0388: Incidence Rate and Factors Associated with Fractures Among Older Adults with Ankylosing Spondylitis in the United States Abstract 0544: Bimekizumab Improves Signs and Symptoms, Including Inflammation, in Patients with Active Non-Radiographic Axial Spondyloarthritis: 24-Week Efficacy & Safety from a Phase 3, Multicenter, Randomized, Placebo Controlled Study Abstract 0545: Continuing (Full or Reduced Treatment) versus Withdrawing from Golimumab Treatment in Patients with Non-radiographic Spondylarthritis Who Achieved Inactive Disease: Efficacy and Safety Results from a Placebo-Controlled, Randomized Withdrawal and Retreatment Study (GO-BACK) What lifestyle factors affect TNF inhibitor efficacy in AxSpA? Dr Chao discusses Abstract 1510 at ACR22 Convergence. Abstract 1510: Modifying Lifestyle Factors May Offer the Potential to Enhance the Outcome of Tumour Necrosis Factor Inhibitors in Axial Spondyloarthritis – Data from 14 European Countries    

Reversing chronic kidney disease (CKD) with a ketogenic lifestyle. Dr. Nally's Ketogenic Dietary Information: https://www.docmuscles.com/dietpage/ Show References: 1. Siperstein MS, Unger RH, Madison LL. “Further Electron Microscopic Studies of Diabetic Microagniopathy.” Early Diabetes: Advances in Metabolic Disorders, sup 1. New York: Academic Press, 1972, p261-271. 2. Nasr SH, D'Agati VD. “Nodular glomerulosclerosis in the nondiabetic smoker.” J Am Soc Nephrol. 2007;18(7):2032. 3. Poplawski MM, Mastaitis JW, Isoda F, Grosjean F, Zheng F, Mobbs CV (2011) Reversal of Diabetic Nephropathy by a Ketogenic Diet. PLoS ONE 6(4): e18604. doi:10.1371/journal.pone.0018604 4. Kundu S, Hossain KS, Moni A, Zahan MS, Rahman MM, Uddin MJ. Potentials of ketogenic diet against chronic kidney diseases: pharmacological insights and therapeutic prospects. Mol Biol Rep. 2022 Oct;49(10):9749-9758. doi: 10.1007/s11033-022-07460-8. Epub 2022 Apr 20. PMID: 35441940. 5. Rojas-Morales P, León-Contreras JC, Sánchez-Tapia M, Silva-Palacios A, Cano-Martínez A, González-Reyes S, Jiménez-Osorio AS, Hernández-Pando R, Osorio-Alonso H, Sánchez-Lozada LG, Tovar AR, Pedraza-Chaverri J, Tapia E. A ketogenic diet attenuates acute and chronic ischemic kidney injury and reduces markers of oxidative stress and inflammation. Life Sci. 2022 Jan 15;289:120227. doi: 10.1016/j.lfs.2021.120227. Epub 2021 Dec 16. PMID: 34921866. 6. Jolliffe N, Smith HW. The excretion of urine in the dog. I. The urea and creatinine clearances on a mixed diet. Am J Physiol 98: 572–577, 1931. 7. Parving HH, Noer J, Kehlet H, Mogensen CE, Svendsen PA, Heding L. The effect of short-term glucagon infusion on kidney function in normal man. Diabetologia 13: 323–325, 1977pmid:334617. 8. Fioretto P, Trevisan R, Velussi M, Cernigoi A, De Riva C, Bressan M, Doria A, Pauletto N, Angeli P, De Donà C, et al. Glomerular filtration rate is increased in man by the infusion of both D,L-3-hydroxybutyric acid and sodium D,L-3-hydroxybutyrate. J Clin Endocrinol Metab. 1987 Aug;65(2):331-8. doi: 10.1210/jcem-65-2-331. PMID: 3298305. #CKD #ChronicKidneyDisease #Kidney #diabeticNephropathy #Diabetes #LeadFolloworGetOutOrMyWay #JustKeepEsterifying #Ketogenic #Keto #KetogenicLifestyle #Carnivore #DrAdamNally #DocMuscles #DocMusclesLive #DocTalk #DocsWhoLift #LiftRunShoot #DocMusclesLife YouTube.com/drnally/.

Dr. Christopher Palmer is today's guest on the Better show. Today we talk about the metabolic underpinning of mental illness such as depression, anxiety, bi polar disorder etc. Chris received his medical degree from Washington University School of Medicine, interning and doing his psychiatry residency at McLean Hospital, Massachusetts General Hospital & Harvard Medical School. He's currently the Director of Dept. of Post Graduate and Continuing Education at McLean Hospital, and an Assistant Professor of Psychiatry at Harvard Medical School. We begin by explaining the role of the mitochondria in our metabolism and it's impact on the body and brain. We discuss new hypothesis in regards to mental illness maybe not being simply a chemical imbalance, and how exercise can aid in the remission of certain symptoms for a time. Chris educates us on the Over Active Brain, as well as the Under Active Brain, touching on the hormonal impact of menstruation and menopause on depression and anxiety. We polish off today's incredibly insightful episode with the origin of the Ketogenic diet, and how it's use can benefit certain people. Dr. Palmer describes the multitude of other benefits of tuning in your mitochondrial efficiency, including sleep regulation and sunlight exposure. A big thank you to Chris for coming on the show, be sure to be on the lookout for his upcoming book “Brain Energy”. If it was as educational as this episode you may want to pre order it at the link below. Episode Overview: 0:00 Introduction2:00 Metabolic Disorders of the Brain 6:00 Mitochondrial Health & Functions16:00 Old vs New Hypothesis in Mental Illness    22:00 Exercise Efficacy on Symptoms of Depression26:30 Over Active Brains35:10 Perimenopausal Hormone Impact on Brain Function 38:30 Under Active Brains49:00 Chris's Take on the Ketogenic Diet1:04:30 Other Benefits of Mitochondrial Efficiency1:14:00 ConclusionSign up for my FREE MASTERCLASS: HEALTHY OFFERS - for health practitioners looking for strategies to earn more moneyAre you A Healthcare Practitioner? Join The Estima Certification Program HereJoin the Hello Betty AMA here: https://www.hellobetty.club/ama We'd like to thank our sponsors, The DNA  Company - $50 discount using code "DRSTEPHANIE" at checkout. https://www.thednacompany.com/drstephanieHVMN Ketones - get 10% off your order with Promo Code “STEPHANIE”  https://hvmn.me/STEPHANIEAthletic Greens - redeem an exclusive offer here: athleticgreens.com/stephanieLMNT Electrolytes - A FREE 7-flavor sample pack! - https://www.drinklmnt.com/DrEstimaOrion Red Light Therapy - Use the code STEPHANIE10 for 10% off + 40% off storewide until September 5th https://www.orionrlt.ca/?ref=StephanieLumen - get $25 off your order with Promo Code “DRSTEPHANIE25” https://www.lumen.me/?fid=1799Ancestral Supplements - Use Promo Code “ASA10” for 10% off any purchase https://shop.ancestralsupplements.com/discount/Tribe10?rfsn=5900205.652074&utm_source=refersion&utm_medium=affiliate&utm_campaign=5900205.652074PRIMEADINE - get 10% Off your Order with Promo Code “DRSTEPHANIE10” - https://oxfordhealthspan.com/products/best-spermidine-supplementBIOOPTIMIZERS - receive 10% off your order with Promo Code "ESTIMA" - www.biooptimizers.com/drstephanie Follow Me On Instagram: https://www.instagram.com/dr.stephanie.estimaGet yourself a copy of my best-selling book, The Betty Body - https://bettybodybook.comJoin the Hello Betty Community here - https://hellobetty.club Dr. Chris Palmer's Links: Pre-Order “Brain Energy” https://www.penguinrandomhouse.com/books/710914/brain-energy-by-christopher-m-palmer-md/

Dr. William Cromwell specializes in the diagnosis and management of lipid (cholesterol and triglyceride) and metabolic disorders. In addition to 30 years of clinical practice experience, his career includes 14 years of service as Medical Director / Division Chief of Lipoprotein and Metabolic Disorders at multiple institutions, 6 years as Chief Medical Officer of one of the world's most innovative lipoprotein diagnostic companies, LipoScience, and 4 years as Strategic Director / Discipline Director of Cardiovascular Disease at LabCorp. Throughout this journey, his motivation has been to create strategies that optimize patient-specific care. This is a significant challenge in the current health care environment. Find Dr. Cromwell: https://precisionhealthreports.com/bio/wcromwell Timestamps 00:00 Lipoproteins 04:09 Atherogenic lipoproteins, APO-B 06:52 Cholesterol not a good marker of cardiovascular risk 19:11 Plaques in young adults 23:03 Low-carb diets not making a difference in some people 25:13 LDL-skeptic 29:48 APO-B, APO-A relationship 33:34 HLD vs LDL 34:39 Glycation damage 37:50 Different types of plaque and thrombosis 41:29 CAC score pros and cons 48:06 APO-B better measure than LDL 50:29 Genetic vs therapeutic answer 56:11 PCSK-9 function 59:01 Precision Health Reports See open positions at Revero: https://jobs.lever.co/Revero/ Join Carnivore Diet for a free 30 day trial: https://carnivore.diet/join/ Book a Carnivore Coach: https://carnivore.diet/book-a-coach/ Carnivore Shirts: https://merch.carnivore.diet Subscribe to our Newsletter: https://carnivore.diet/subscribe/ . ‪#revero #shawnbaker #Carnivorediet #MeatHeals #HealthCreation #humanfood #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree ‪ Dr. William Cromwell specializes in the diagnosis and management of lipid (cholesterol and triglyceride) and metabolic disorders. In addition to 30 years of clinical practice experience, his career includes 14 years of service as Medical Director / Division Chief of Lipoprotein and Metabolic Disorders at multiple institutions, 6 years as Chief Medical Officer of one of the world's most innovative lipoprotein diagnostic companies, LipoScience, and 4 years as Strategic Director / Discipline Director of Cardiovascular Disease at LabCorp. Throughout this journey, his motivation has been to create strategies that optimize patient-specific care. This is a significant challenge in the current health care environment. Find Dr. Cromwell: https://precisionhealthreports.com/bio/wcromwell Timestamps 00:00 Lipoproteins 04:09  Atherogenic lipoproteins, APO-B 06:52 Cholesterol not a good marker of cardiovascular risk 19:11 Plaques in young adults 23:03 Low-carb diets not making a difference in some people 25:13 LDL-skeptic 29:48 APO-B, APO-A relationship 33:34 HLD vs LDL 34:39 Glycation damage 37:50 Different types of plaque and thrombosis 41:29 CAC score pros and cons 48:06 APO-B better measure than LDL 50:29 Genetic vs therapeutic answer 56:11 PCSK-9 function 59:01 Precision Health Reports See open positions at Revero: https://jobs.lever.co/Revero/ Join Carnivore Diet for a free 30 day trial: https://carnivore.diet/join/ Book a Carnivore Coach: https://carnivore.diet/book-a-coach/ Carnivore Shirts: https://merch.carnivore.diet Subscribe to our Newsletter: https://carnivore.diet/subscribe/ . ‪#revero #shawnbaker #Carnivorediet #MeatHeals #HealthCreation   #humanfood #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree  ‪

This episode goes deep on something called cardiometabolic risk, understanding lipoproteins and metabolic disorders. I’m here with Dr. William Cromwell, who is the chief of the Lipoprotein and Metabolic Disorders Institute in Raleigh, North Carolina, and who is one of the foremost experts in the world on these topics. I think this is a really …

This episode goes deep on something called cardiometabolic risk, understanding lipoproteins and metabolic disorders. I’m here with Dr. William Cromwell, who is the chief of the Lipoprotein and Metabolic Disorders Institute in Raleigh, North Carolina, and who is one of the foremost experts in the world on these topics. I think this is a really …