Podcasts about HP

Jane's purpose is to create the environment and leadership that enables growth and fulfilment. She does this through listening. Listening to ignite the best thinking, ideas and solutions in others. In her executive coach and facilitator roles she supports individuals and teams develop human-centric leadership and cultures where everybody matters generating people and business growth in harmony. She is an Ambassador for Truly Human Leadership and hosts a thought led community in developing this approach to leadership.Jane is a master credited coach with the ICF and global faculty member with Time to Think. Jane brings the thinking environment to life for others through her teaching all courses to the qualifying level and offers supervision to thinking environment practitioners.Jane has over 35 years' experience within people focused roles in professional and financial services. Her experience includes Director of her own coaching practice, and HR Executive within European and US Investment Banks and an International Law Firm where she was responsible for the strategy and implementation of resourcing and development of people across front line businesses. Jane's work is underpinned with post graduate diplomas in Human Resources Management and Psychological Coaching. Jane is also author of The Listening Coach – Coach yourself through the elements of listening that are critical in life business and our communities and Are you listening, or just waiting to speak? – The secret to propelling your business relationships.Current and former clients include Munich Re, Rothschilds, Columbia Threadneedle, Pask Partnership, The Marketing Academy, Deloitte, Bottomline Technologies, Sony Pictures, Barry Wehmiller, Ince & Co, Land Securities, HP.Link to claim CME credit: https://www.surveymonkey.com/r/3DXCFW3CME credit is available for up to 3 years after the stated release dateContact CEOD@bmhcc.org if you have any questions about claiming credit.

325 | Lashay Lewis helps B2B SaaS companies create profit driven content strategies. We talk about why a B2B content strategy should be built from the bottom of the funnel up, why she interviews sales teams to understand "life before using the product" and why she interviews customer success teams to understand "life after using the product" and how that influences content strategy, how writing influences buyers, the power of a strong company POV, training in-house writers and freelancers in a way that scales, where podcasting fits in a B2B content strategy, why search volume can be misleading, and thoughts on how content marketers can use AI. Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Are product marketers actually marketers, or are they just glorified slide deck designers waiting for sales to bark orders? David Lim—a PMM who's survived Google, HP, and multiple startups—joins the skeleton crew to drop some uncomfortable truths. We talk about earning respect when founders don't have a clue what you do, why knowing your customer's quarterly priorities is a superpower, and what happens when you fight a C-suite exec on product strategy (spoiler: sometimes you get fired). If you've ever been asked to "make that deck pretty," this one's for you.More From This EpisodeThe brutal truth: What happens when you don't earn internal respect as a PMMWhy sales teams don't talk to product teams (and how PMMs become the bridge)The one customer question David asks that unlocks everything: "What are your quarterly priorities?"David got fired for fighting a founder on product strategy—here's what he learnedWhy most founders have zero idea what PMMs actually do (and think you're just a lead gen machine)The "gut feeling" trap: When executives ignore your research and launch anywayHow to stop rolling your eyes when leadership makes dumb decisions (David admits he's not good at this)Why working under the product org might actually be better for PMMsThe ultimate PMM flex: Knowing your customer better than anyone in the companyAre PMMs actually marketers, or just the people who make sales decks look pretty?Time Stamps 00:00 Introduction and Season 5 Kickoff00:59 Introducing Guest: David Lim (PMM at BVO)02:36 The Big Question: Are Product Marketers Actually Marketers?04:15 How PMMs Earn Respect (Or Get Stuck in the Black Hole)07:00 What Sets PMMs Apart: Cross-Functional Collaboration09:45 The Research That Changed Everything (Working Under Product Org)13:00 Advocating for PMM: Educating Teams on What You Actually Do16:00 The Metrics Problem: What Should PMMs Own?20:00 Working with Customer Success Teams (QBRs and Product Feedback)23:00 When You Know the Customer Better Than Anyone Else26:00 Understanding Quarterly Priorities (The Detail Most PMMs Miss)29:00 Customer Advisory Boards and Sales Advisory Boards33:00 The Struggle: When Executives Ignore Your Research35:00 David's Story: Getting Fired for Fighting Product Strategy38:00 Gab's Story: When a Writer Called the Product "Shit"40:00 Rolling with the Punches (And Why It's Hard)42:00 In-House vs. Agency PMM: The Respect Difference45:00 Post-Launch Research: The Key to Proving You Were Right47:00 The Founder Talk: Setting Clear Expectations49:00 Understanding the Customer's Buying Process50:00 Wrap-Up and Where to Find DavidHosted on Ausha. See ausha.co/privacy-policy for more information.

How can leaders ensure their message lands with clarity, confidence, and influence? In this episode, Kevin Eikenberry sits down with Dr. Laura Sicola to discuss how leaders can strengthen their influence by mastering their leadership voice. Laura introduces her "vocal executive presence" framework, built around the three Cs: Command the room, Connect with the audience, and Close the deal. Kevin and Laura break down the three communication channels every leader uses—verbal, vocal, and visual—and why alignment across all three is essential for credibility. They unpack common leadership communication pitfalls, such as overwhelming others with too much "relevant" information instead of focusing on what is truly essential, and how habits like vocal fry, weak openings, or cluttered slides can quietly erode influence. Laura also shares memorable frameworks, including the 60-to-60 rule for opening meetings and the "prismatic voice" to remain authentic in different situations. Laura's Story: Dr. Laura Sicola is an executive communication coach, 3x TEDx speaker, and author of Speaking to Influence: Mastering Your Leadership Voice. With over two decades of experience working with Fortune 500 companies, global nonprofits, and government agencies, she empowers leaders to show up powerfully and speak with confidence in high-stakes conversations. Her proprietary "Vocal Executive Presence" framework helps leaders command the room, connect with their audience, and close the deal. She is a cognitive linguist by training and former faculty at the University of Pennsylvania. Her TEDx talk has nearly 7 million views, and her client list includes Amazon, Intel, HP, Kaiser Permanente, and the U.S. Department of Commerce. https://laurasicola.com/ https://www.linkedin.com/in/drlaurasicola https://x.com/LauraSicola https://www.facebook.com/drlaurasicola/ https://www.youtube.com/@LauraSicolainc https://www.tiktok.com/@laurasicola https://podcasts.apple.com/us/podcast/speaking-to-influence/id1515649028 This Episode is brought to you by... Flexible Leadership is every leader's guide to greater success in a world of increasing complexity and chaos.  Book Recommendations Speaking to Influence: Mastering Your Leadership Voice by Dr. Laura Sicola Mental and Emotional Release by Dr. Matt James and Tris Thorp Like this? Influence Redefined with Stacey Hanke You Have More Influence Than You Think with Vanessa Bohns Increase Your Leadership Influence wirh Jake Thompson  

Pikes Peak and land speed record racing couldn't be more different when it comes to motorsport, and that's exactly why Scott Birdsall from Chuckles Garage is so interesting. From 1,000+ HP diesel hill climb monsters to a 2JZ-powered, land speed record-holding Toyota Hilux, Scott is into everything cool and fast.

#324 | Dave is joined by three marketing leaders from different industries to talk on a live session about AI and SEO and what they've learned over the last year. Dave Steer (CMO at Webflow), Marcy Comer (CMO at EagleView) and Clare Schmitt (VP, Marketing & Communications at Piedmont Global) break down how buyers are learning about products through ChatGPT and why traditional SEO fundamentals still matter. The group shares real examples of how they're approaching content, prompt tracking, PR, and brand authority, plus advice for marketers on where to focus, what to ignore, and how to guide their teams through this search shift.Timestamps(01:06) - Why AI + SEO is the hottest (and most confusing) topic in B2B marketing right now (05:37) - Meet the panel: marketing leaders from Webflow, EagleView, and Piedmont Global (09:15) - How AI search is changing buyer behavior vs traditional Google search (12:58) - EagleView's real approach to AI search, greenfield opportunities, and prompt tracking (16:05) - What “black hat” vs “white hat” tactics look like in AI-driven search (20:12) - Webflow's take: integrated marketing, generosity, and building useful tools (29:33) - Getting past high-level advice and into real execution (34:33) - “Circle the buyer”: how content builds demand before buyers are in-market (38:16) - Why PR is back: long-form press, citations, and brand credibility in AI search (45:16) - What to do if you're a startup with no budget: focus on positioning first Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Join host Paul Spain as he sits down with Sam Vye of Syos Aerospace, a trailblazing New Zealand tech company shaking up the unmanned vehicle industry. Hear how Syos rapidly prototypes cutting-edge drones, outpaces global defence giants, and scales from Kiwi innovation to international contracts. Discover their unique engineering culture, rapid product development, and what it takes to compete with the world's biggest aerospace companies.Thanks to our Partners One NZ, Workday, 2degrees, HP, Spark and Gorilla Technology

出演者：藤原鞠菜 配信ペース：隔週火曜日 番組時間：平均40分 ——————————————————————— ＜各テーマ紹介＞配信されるテーマは回によって異なります。 「ふつおた」･･･何でもありのお便りコーナー。投稿は毎日募集中！！！！！ 「歴史秘話ウィステリア」･･･サークル曲の裏話など。 「まりにゃのこれな～んだ？」･･･音当てクイズ。 「まりにゃのオススメ」･･･オススメ商品をご紹介。 「はじおと」･･･「音楽」×「初めて」に関して語るコーナー。 （初めて買ったCD、初めて心を動かされた音楽、初めてカラオケで歌った曲等。） 「これかた」･･･テーマを決めて語る割とフリーダムなコーナー。 （テーマや語ってみた投稿募集中。） 「答えて、まりにゃ」･･･まりにゃへの質問募集中。 「トレンドなう」･･･収録時に開いたTwitterのリアルタイムトレンドについてコメント。 「まりにゃのTOP5」･･･思いついたら勝手にランキング。 「まりにゃのドキドキ質問箱」…twitter投稿になります。（ https://peing.net/marinya_）  「みんなの答え合わせ」…twitterで出題するアンケートの結果報告。みんなに聞きたいこと募集中。 ——————————————————————— ——————————————————————— ■CD新作・出演告知など■ ★Wisteria Magic通販サイト「うぃすましょっぷ」★ wismashop.booth.pm/ 新作も旧作も全て送料込み！ ★イオシスショップ様にて一部旧作を委託販売中！★ www.iosysshop.com/SHOP/list.php?Search=wisteria ★しがないレコーズのyoutube「しがない5分ショー」に出演してます。 藤原鞠菜は木曜日担当です。 https://www.youtube.com/channel/UCA_FmkoMu24R_6o3m3_Ulqg —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ・の〜すとらいく様の18禁PCゲーム 「女装百合畑/Trap Yuri Garden」にて、主題歌「優雅にヒロイン宣言」を担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして！夜までもっとエッチして！」 にて女未こはくちゃん(三女)のED曲担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして!」 にて女未こはくちゃん(三女)のED曲を担当させて頂きました。 —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ——————————————————————— この番組は音楽サークルWisteria Magicがお届けする番組です。 藤原鞠菜やサークルの過去または最新の活動内容につきましては 以下をチェックしてくださると嬉しいです♪ ・藤原鞠菜のTwitter（ twitter.com/marinya_ ） ・藤原鞠菜のHP「ふじわらんど」（ fujimari.com/ ） ・磯村カイのTwitter（ twitter.com/isomurakai ） ・磯村カイのHP「TONAKAI soundworks」（ https://soundworks.tonakaii.com/ ） 藤原鞠菜への贈り物の宛先 〒107-0052 東京都港区赤坂4-9-25 新東洋赤坂ビル10F レイズイン　アカデミー気付　藤原鞠菜宛 VOICEVOX:ずんだもん VOICEVOX:四国めたん

My guest this week is Joseph Perello, founder and CEO of Props. Props is a performance-based creator marketing platform built around a simple belief. The best marketing still comes from people, not metrics. Instead of chasing follower accounts, Props uses AI to match brands with creators based on storytelling strength, trust, and audience authenticity. So campaigns are both data-driven and deeply human.AI does the heavy lifting in the background, brand safety, workflow and precision, while real human creators stay in front and center. Before launching Props, Joe built and ran a digital agency serving brands like Nike, HP, Lowe's Hotels, Betterment, and even Michelle Obama. And earlier in his career, he served as New York City's first CMO under Mayor Bloomberg, helping to revitalize tourism and launching the city's first self-sustaining marketing agency. Finally, Joe sits at the intersection of brand, policy, tech, and creative. I'm so happy I spent a few minutes with him at advertising week not long ago, and we're gonna continue that great conversation.

Explore how Apple is transforming Siri into a Gemini-powered AI chatbot, why emotional voice AI is the next frontier, and how HP's Elite Board G1—the PC in a keyboard—may be a game-changer for blind users. Steven Scott and Shaun Preece dive into the major tech stories shaping 2026. They unpack Bloomberg's report that Siri will evolve into a fully integrated AI chatbot powered by Google's Gemini, raising questions about privacy, speed, and Apple's long-term AI strategy. The hosts debate why the term “chatbot” carries negative connotations and how Apple could regain trust after its shaky Apple Intelligence rollout. The discussion then shifts to emotional AI and Google DeepMind's acquisition of Hume AI's Alan Cowan. They explore how future voice assistants could detect and respond to human emotion, potentially revolutionizing AI companionship, therapy, and conversational interfaces for everyone. Later, Steven interviews HP's Caleb Fleming about the Elite Board G1, a Windows 11 PC built inside a keyboard with up to 64GB RAM and 2TB storage. They discuss its upgradeability, enterprise focus, and unexpected potential as an ideal computer for blind users without the bulk of traditional desktops or laptops. The episode closes with quick takes on Sony LinkBuds Clip open-ear audio and Toronto Police trialling AI for non-emergency calls. Relevant LinksBloomberg – Siri AI Chatbot Report: https://www.bloomberg.comHP Elite Board G1: https://www.hp.comHume AI: https://www.hume.ai Find Double Tap online: YouTube, Double Tap Website---Follow on:YouTube: https://www.doubletaponair.com/youtubeX (formerly Twitter): https://www.doubletaponair.com/xInstagram: https://www.doubletaponair.com/instagramTikTok: https://www.doubletaponair.com/tiktokThreads: https://www.doubletaponair.com/threadsFacebook: https://www.doubletaponair.com/facebookLinkedIn: https://www.doubletaponair.com/linkedin Subscribe to the Podcast:Apple: https://www.doubletaponair.com/appleSpotify: https://www.doubletaponair.com/spotifyRSS: https://www.doubletaponair.com/podcastiHeadRadio: https://www.doubletaponair.com/iheart About Double TapHosted by the insightful duo, Steven Scott and Shaun Preece, Double Tap is a treasure trove of information for anyone who's blind or partially sighted and has a passion for tech. Steven and Shaun not only demystify tech, but they also regularly feature interviews and welcome guests from the community, fostering an interactive and engaging environment. Tune in every day of the week, and you'll discover how technology can seamlessly integrate into your life, enhancing daily tasks and experiences, even if your sight is limited. "Double Tap" is a registered trademark of Double Tap Productions Inc. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

出演者： miko、quim 配信ペース： 隔週水曜日（遅延） 番組時間：92分55秒 ♯本番組はリモート収録です。 ♯収録時環境の影響により、全体的に聴き取り辛くなっております。 　申し訳ございません。 2026年の配信2回目から大遅刻！ mikoラジ、第389回です。 お仕事で忙しい我さん。しがないさんと一緒に社畜トークに花が咲きます（？）。 10代リスナーが増えているらしいのに、とってもしみったれとぅないと。 若人よ、これが大人だ……（真似しないでね）。 最後までごゆるりとお楽しみくださいませ。 ♯途中で色々とノイズ等入りますが、収録時のものです。 　ご安心ください、お手持ちの機器は正常です。 //////////////////// VOICEVOX:ずんだもん VOICEVOX:四国めたん //////////////////// -------------------- ●お便り募集中！ mikoラジでは以下の内容でお便りを募集中です！ ・ふつおた 　／普通のお便り、お待ちしています！ ・mikoは大変な絵を描いていきました 　／miko画伯に描いて欲しいお題をお待ちしています！ ・メシヲコエテ 　／料理人・mikoに教えて欲しいレシピをお待ちしています！ bit.ly/2GAWjyv 投稿フォームからラジオに投稿が出来ます！ コーナー名を選び、メッセージ・ラジオネーム・お所を入力して、 どんどん送ってください！　お待ちしています！！ ------------ 本ラジオのメインパーソナリティーである「チーム我等(miko/quim)」、 それぞれ以下個人サークルにて活動中です。 ・miko：miko ・quim：SHIGANAI RECORDS（ shiganai.com/ ） 活動詳細については、上記HPの他 各人のブログ/twitter等にて随時告知しておりますので、チェックしてみてください！ ・みころぐ。(mikoのブログ)（ ameblo.jp/miko-nyu/ ） ・@ mikonyu(mikoのtwitter)（ twitter.com/mikonyu ） ・@ quim(quimのtwitter)（ twitter.com/quim ） --- その他の活動については、以下のとおりです！ -- チーム我等がメインクルーとして活動していた「アルバトロシクス（ albatrosicks.com/ ）」、 これまでリリースしたCDは、イオシスショップ（ iosys.booth.pm/ ）にて頒布しております。ご興味ある方は是非！ ---------- ☆2025年1月IOSYSはいてない.comパワープレイ楽曲 M1. YATSUZAKI HARDCORE (Liqo NEXT100 Remix) 作曲：SHC crew リミックス：Liqo 音楽ジャンル：Hardcore 収録アルバム：YATSUZAKI HARDCORE COLLECTION 2025 2025・12・31 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-1005 変わらぬ"やりたい音"を、札幌から全世界へ！ YATSUZAKI HARDCOREが贈る2025年総まとめコンピレーション！

Story of the Week (DR):CEOs are finding their blowhard whistles?Jamie Dimon is done being ‘binary': On Trump's ‘economic disaster' credit card plan, foreign policy, and NATOJamie Dimon issues rare CEO criticism of Trump's immigration policy: 'I don't like what I'm seeing'JPMorgan CEO Jamie Dimon said Trump's proposed 10% cap on credit card rates would be an 'economic disaster'Jamie Dimon issues rare CEO criticism of Trump's immigration policy: 'I don't like what I'mOf course… Trump sues ‘woke' JP Morgan for $5bn over debanking Nestlé chief blames Trump for company going quiet on sustainabilityAmazon CEO Jassy says Trump's tariffs have started to 'creep' into prices Ryanair CEO rips Trump as a 'liar' who is 'historically wrong'Of course… Minneapolis ICE Standoff Has Become the Political Issue CEOs Can't IgnoreEmployees in Minnesota are afraid to show up to workTarget in Your Town: How We're Showing Up in Communities from Coast to CoastLast "statement:" Target Statement on Texas Floods (July 8, 2025)And two new dudes on the board:John Hoke, former Chief Innovation Officer at NIKESteve Bratspies, former CEO of HanesBrandsSome stakeholder wins?Trump administration drops appeal over anti-DEI funding threat to schools and colleges Trump administration concedes DOGE team may have misused Social Security dataJamie Dimon tells Davos: ‘You didn't do a particularly good job making the world a better place'Jamie Dimon says government should have power to intervene in AI-driven mass layoffsRollout of AI may need to be slowed to ‘save society', says JP Morgan bossSalesforce's Benioff calls for AI regulation, says models have become 'suicide coaches'BlackRock's billionaire CEO warns AI could be capitalism's next big failure after 30 years of unsustainable inequality after the Cold WarBlackRock CEO says capitalism isn't spreading the wealth – and AI might not eitherBrett Kavanaugh says letting Trump fire Lisa Cook ‘would weaken, if not shatter, the independence of the Federal Reserve'A majority of millionaires say extreme wealth is a threat to democracyAmazon Joins Microsoft In Pledge To Self-Fund Power Grids, While CEO Andy Jassy Questions OpenAI's 'Ambitious' SpendingThe board matters??Lululemon founder Chip Wilson blames board for 'total operational failure' in Get Low launch [more later]Early 2026 season proxy indicators MMApple: 1 SHPNational Center for Public Policy Research: China Entanglement AuditExcluded: National Legal and Policy Center: Financial Impact of Renewable Energy ImplementationDisney: 4 SHPsBowyer Research: How the Employee Gift-Matching Program May Impact Risks Related to Religious Discrimination Against EmployeesNational Center for Public Policy Research: Return on Investment from Climate CommitmentsNational Legal and Policy Center: Cumulative Voting for Board ElectionsErik G. Paul: Accessibility and Disability Inclusion PracticesQualcomm: 2 SHPsJohn Chevedden: Shareholder Ability to Call for a Special Shareholder MeetingBowyer Research: Risk of China ExposureGoodliest of the Week (MM/DR):DR: America could ‘lose the AI race' because of too much ‘pessimism,' White House AI czar David Sacks saysMM: Elon Musk Says 'They Will Eventually Apply the Wealth Tax to Everyone' —Just Like How Income Tax Started As A 'Temporary' Tax For Top 1%This is a great ideaMM: AOC and Paris Hilton team up on a bill targeting AI deepfake pornWhat a teamAssholiest of the Week (MM):Governance asshole: Chip Wilson DRLululemon's founder is blasting the company for selling sheer leggings, calling it a 'new low'Lululemon founder Chip Wilson blames board for 'total operational failure' in Get Low launch“In 2013, Lululemon recalled 17% of all its pants for being too sheer. At that point, the company blamed the manufacturing error on an incomplete testing protocol”Wilson owned 29.22% of the stock at the timeSAME BOARD MEMBERS THAT CHIP WILSON PICKED:Martha Morfitt (2008)David Mussafer (2014)Michael Casey (2007)Emily White (2011)40% of the board IS CHIP WILSON'S HAND PICKED PEOPLELast week: Lululemon founder Chip Wilson launches proxy fight for board shakeupWilson has nominated three independent director candidates to be elected at the 2026 annual meeting and submitted a proposal to "declassify" the board so that all members must stand for election annuallyHE CLASSIFIED THE BOARD - sucks to be on the outside looking inCapitalist assholes: DavosBlackRock CEO says capitalism isn't spreading the wealth and AI might not eitherBlackRock's $40 billion deal highlights the unstoppable AI data center gold rush, as CEO Larry Fink pushes back on AI bubble fearsJamie Dimon tells Davos: ‘You didn't do a particularly good job making the world a better place'As he attends every year without irony - and this: How Wall Street Turned Its Back on Climate ChangeBillionaire Marc Benioff challenges the AI sector: ‘What's more important to us, growth or our kids?'Salesforce CEO Marc Benioff says he cut 4,000 support roles because of AISo not THEIR kids obviously“Antimicrobial resistance pandemic will kill more people than cancer by 2050 and no one at Davos is talking about it" – leading scientists speak out at Frontiers Science HouseThe anti-education uber-wealthy tech bros:Nvidia's Jensen Huang says it's a good time to be a plumber; and not just because it's an AI-proof jobPalantir CEO says AI ‘will destroy' humanities jobs but there will be ‘more than enough jobs' for people with vocational trainingHeadliniest of the WeekDR: Ryanair launches 'Great Idiots' seat sale 'especially for Elon' as feud escalatesDR: Palantir CEO Alex Karp says humanities jobs are doomed in the age of AI: 'Hopefully you have some other skill'62% of bachelor's degrees in the humanities were earned by women; 63% of mastersMM: Nestlé chief blames Trump for company going quiet on sustainability Uh… you… run… the… company?MM: How anti-doomscrolling influencers are combating social media addictionAlcoholics typically use alcohol to get over their addiction to alcoholWho Won the Week?DR: ani-China right wing blowhardsMM: Private jets: Business Insider tracked at least 157 private jets that arrived near Davos, using data from ADS-B Exchange and JetSpy. They included airplanes belonging to Salesforce CEO Marc Benioff and former Google CEO Eric Schmidt. Jets from companies like Aramco, BlackRock, Blackstone, Citigroup, Google, HP, JPMorgan Chase, Lockheed Martin, and the quantitative hedge fund Two Sigma also arrived in the area.PredictionsDR: Target soft-launches brown-colored oranges to see if America is ready to care about race againMM: Jamie Dimon officially declares himself as “non binary” and requests the media address him as “they” whenever quoting him. They then contacts Fortune after reading this headline about himself - Jamie Dimon says he'd have no issue paying higher taxes if it actually went to people who need it—right now it just goes to the Washington ‘swamp' - and demands an edit to “Jamie Dimon says they'd have generally some but not none issue paying higher or lower taxes if it actually went to poor or rich people, but now it goes to the Washington swamp or everglade or desert, either way it's delightful but also could be terrible.

#323 | Anthony Pierri from Fletch PMM joins Dave to talk about what actually matters in B2B positioning and messaging. They break down how to think about value props, why buyers don't care about your features, and what makes a homepage instantly click. Anthony shares lessons on positioning from working with hundreds of early-stage B2B SaaS companies and explains how to connect real customer problems to clear outcomes. Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

In this episode of the Additive Snack Podcast, host Fabian Alefeld welcomes Kristin Mulherin, the Director of Additive Manufacturing Technology at Hubbell Inc., to discuss the creation and development of an additive manufacturing center of excellence within a 150-year-old corporation. Kristin shares her extensive journey through various roles in the additive industry, from Northrop Grumman to HP, and her significant input in initiatives like Women in 3D Printing. She discusses Hubbell's historical background and the strategic decisions behind establishing the AM center, including technology choices, cost management, and internal education to drive innovation.   The episode covers specific applications, the challenges of shifting from prototyping to production, and the importance of cross-departmental education within the company to leverage the full potential of additive manufacturing.  00:00 Introduction to the Additive Snack Podcast  01:40 Meet Kristen Mulherin: A Journey in Additive Manufacturing  05:07 Kristen's Role at Hubbell Inc. and Industry Insights  06:11 Women in 3D Printing and Leadership  07:46 Building Hubbell Inc.'s Additive Manufacturing Center of Excellence  15:25 Technology Stack and Future Plans at Hubbell  19:30 Exploring New Opportunities in Additive Manufacturing  21:38 Balancing Cost and Lead Time in Additive Manufacturing  22:08 Value Drivers in Additive Manufacturing  

HEADLINES:• Qatar's $580bn Wealth Fund Plans Major Portfolio Split• Netflix Goes All-Cash in $30bn Battle for Warner Bros.• NBA Courts Gulf Sovereign Wealth for European League Pus• HP's Peter Oganesean: How AI and Hybrid Work Are Redefining Productivity in 2025

Level up your B2B marketing and build a brand that actually stands out: subscribe to the Pipe Dream podcast from B2B Better for narrative-driven B2B marketing strategy, media-led content ideas, and practical GTM frameworks from host Jason Bradwell. Tired of AI-generated spam clogging up your inbox? So is everyone else. In this episode, host Jason Bradwell sits down with Mike Adams - founder of Intro Stars and host of The Super Connectors podcast - to talk about why the future of B2B isn't more automation, it's better relationships. Mike shares how he's building a marketplace that turns warm introductions into real business growth, why "super connectors" are becoming the most valuable people in tech, and how any B2B company can launch their own referral program without it feeling sleazy or transactional. If you're tired of cold outreach that doesn't work and LinkedIn DMs that make you cringe, this conversation is for you. Jason and Mike start by tackling the elephant in the room - AI-driven lead generation is failing spectacularly. Everyone's inbox is flooded with personalised-but-not-really messages that feel increasingly desperate and spammy. Mike explains why this approach is burning bridges instead of building them, and what smart B2B companies are doing instead. They dive into the mechanics of building a warm referral program that actually works. Mike breaks down the key components: clear terms and conditions so everyone knows what they're signing up for, intro success fees that align incentives properly, and systems that make it easy for people to make quality introductions without it becoming a second job. The goal isn't to turn everyone into a salesperson - it's to create a structure where natural connectors can do what they already love doing, but with better outcomes for everyone. Mike also unpacks what makes someone a "super connector" and why these people are becoming increasingly valuable in B2B. It's not just about having a big network - it's about being someone who genuinely enjoys bringing people together and has built enough trust that when they make an introduction, both sides pay attention. Mike's even created a super connector certification badge for people who excel at this, which is becoming a real differentiator in the market. They explore how the "intro economy" is emerging as a counter-movement to the automation-everything trend. While AI can do a lot of things, it fundamentally can't build the kind of trust that comes from a warm introduction from someone you respect. Mike shares stories from his time at Zoom, Apple, and HP about how the best deals always came through relationships, not cold outreach. The conversation gets really practical when Mike walks through how to structure an introductions marketplace - what incentives work, how to track success, and how to keep quality high when you're trying to scale. He's learned a lot from building Intro Stars, and he's refreshingly honest about what's worked and what hasn't. Throughout the episode, both Jason and Mike keep coming back to a central theme: in an age where anyone can automate outreach at scale, the real competitive advantage is being genuinely human. Building relationships takes longer, but the ROI is dramatically better and the relationships actually last. If you're a B2B marketer watching your response rates plummet while your competitors keep cranking up the automation, this conversation offers a different path forward. Mike and Jason make a compelling case that the antidote to AI spam isn't better AI - it's better relationships. Whether you're at a startup trying to get your first customers or a scale-up looking to break into enterprise, the principles Mike shares about warm introductions and super connectors can transform how you think about growth.

Book 7, Chapter 3: The Dursleys Departing

#322 | Louis Grenier joins Dave for a conversation about what it actually takes to stand out in B2B marketing when everything feels the same. Louis sent Dave 10 surprise gifts to open during the show, and each one sparks a conversation about marketing, career, and life. They talk about the reality of how people decide to buy and why Louis is so focused on timeless fundamentals.Timestamps(00:00) - — Timeless marketing vs the AI hype (05:24) - — The colonoscopy story. (12:44) - — Trojan Horse marketing. Get attention first. Sell later. Stop leading with your product. (17:44) - — Why you can't create demand, only redirect it. (23:24) - — Category creation vs sub-categories. Most startups get this wrong. (26:14) - — Meaning-free brand assets. Why weird mascots and visuals actually work. (33:18) - — How to sell bold ideas internally without asking for permission. (37:08) - — Ads that look like ads fail. Attention is the job. (45:48) - — Triggers vs pain points. How people actually decide to buy. (51:08) - — First principles, repetition, history, and why this stuff still works no matter the tech wave. Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Highly accomplished CMO and Advisor Andrea Hogan shares her journey in leading major go-to-market initiatives for an $11 billion region at Qualcomm, working with technology giants Google, Microsoft, Dell and HP building compelling, innovative ecosystems. Her leadership philosophy doesn't come from board rooms, it comes from unforgettable life experiences like walking 800 kilometers across Spain on the Camino de Santiago. carrying just 7 kilos in her backpack and her mother's journal. This walk represented the very critical leadership prioritization choices we must make. "The Camino strips life back to essentials. You realize how much of what we carry, not just in our backpacks, but in our lives, isn't truly essential." Being an impactful leader is not about just about strategy and techical competency. It's about bringing an optimistic mindset every day in inspiring and creating future generations of great leaders. "Leadership isn't about being followed. It's about creating more leaders. The greatest measure of your success is how many people rise because of you."

                                   Copperplate Time 524                                presented by Alan O'Leary                             www.copperplatemailorder.com                                          My Glasgow Visit 1. BOTHY BAND:  Green Groves of Erin/Flowers of Red Hill. After Hours 2. JIMMY McHUGH: Pidgeon on the Gate.  2nd Jimmy McHugh Memorial Concert3. BRENDAN & MARTIN McHUGH:       MarionKelly's/Carey's Cottage.  2nd Jimmy McHugh Memorial Concert 4. BRIDGE CEILI BAND: Lord McDonald's/The Holly Bush/Finbarr Dwyer's.                          Sparks on Flags 5. PAUL McGLINCHEY & MACDARA O'RAGHALLAIGH:                 Lord Ramsey's/The Jolly Tinker/The Rainbows End.  Unearthed6. CHRISTY MOORE:  By Clyde's Bonnie Banks. Live in Dublin 7. KEVIN ROWSOME: The Musical Pulse  of the Blaskets.                     The Musical Pulse of the Pipes8. MICK MULVEY:  The Brook//The Killukin Ghost/Salute to Sherlock.              The Missing Guest 9. MICHAEL ROONEY & JUNE McCORMACK:           Colonel McBain's/Paddy Kiloran's.  Lands End 10. EILEEN O'BRIEN & LAR GAVIN:      The Poppy Leat/McIntyre's HP.   2nd Jimmy McHugh Memorial Concert 11. SEÁN ÓSÉ:  Do Bhí Bean Uasal.   O'Riada sa Gaiety 12. PJ CROTTY & JAMES CULLINANE:                    Sheep in the Boat/Hurry the Jug. Happy to Meet13. ANGELINA CARBERRY & DAN BRUDER:               Curlews in the Bog/Tommy People's/The Monsignor's Blessing.                    A Waltz for Joy 14. EILIS KENNEDY:   Ciumhais Charrig Aonair. So Ends This Day 15. PADDY CARTY & CONOR TULLY:                    Dowd's/In Memory of Coleman. Trad Music of Ireland 16. DERMOT BYRNE, JOHN DOYLE & EAMONN COYNE:                  Highland & Reels.  Liag 17. PJ & MARCUS HERNON:  Gallagher's Frolics/Tae ar an bPortach/An Buachaillin Bán.  Celebrating 50 Years 18. MICHAEL BANAHAN:  Winter in the City.   Broken Heart 19. CILLIAN VALLELY & DAVID DOOCEY:                    The Peacock's Feather.  The Yew & The Orchard 20. KEVIN BURKE & JOHN BRENNAN:                    London Town.   The Piound Ridge Sessions 21. BOTHY BAND: Green Groves of Erin/Flowers of Red Hill.   After Hours                                                 http://copperplatemailorder.com

Greg Kihlström shares groundbreaking insights into how businesses can become experience-led enterprises. With real-world examples and a focus on innovation, Greg discusses digital transformation, agile methodologies, and the pivotal role of customer and employee experiences in driving success. This is a must-listen for anyone passionate about transforming organizations and delivering exceptional value to customers and teams alike. About the Guest Greg Kihlström is a best-selling author, speaker, and entrepreneur, and serves as an advisor and consultant to top companies on marketing technology, marketing operations, and digital transformation initiatives. He has worked with some of the world's top brands, including Adidas, Coca-Cola, FedEx, HP, Marriott, Nationwide, Victoria's Secret, and Toyota. He is a multiple-time Co-Founder and C-level leader, leading his digital experience agency to be acquired in 2017, successfully exited an HR technology platform provider he co-founded in 2020, and led a SaaS startup to be acquired by a leading edge computing company in 2021. He currently advises and sits on the Board of a marketing technology startup. Relevant Links https://www.linkedin.com/in/gregkihlstrom https://www.instagram.com/theagilebrand https://www.gregkihlstrom.com Episode Summary - The Top 3 Key Learnings Four Pillars of Transformation: Effective digital transformation hinges on integrating people, processes, platforms, and data. While technology matters, success ultimately depends on how well organizations address human and procedural challenges. Agile for Transformation: Agile methodologies can look different for every organization. Focus on principles like collaboration, adaptability, and delivering business value, rather than rigidly adhering to predefined methods. Return on Experience: Investing in customer and employee experiences yields measurable benefits, such as increased customer loyalty, higher lifetime value, and improved organizational efficiency. Chapters 00:00 Introduction and Guest Welcome 00:33 Greg Kihlström's Background and Career 01:55 Values Driving Professional Life 02:54 Digital Transformation Challenges 05:11 Measuring Return on Experience 09:23 Implementing Agile Methodologies 14:10 Practical Tips for Digital Transformation 16:47 AI in Digital Transformation 22:14 Future of Customer Experience 24:23 Conclusion and Final Thoughts Please, hit the follow button and leave your feedback: Apple Podcast: https://www.cxgoalkeeper.com/apple Spotify: https://www.cxgoalkeeper.com/spotify About the host: Gregorio Uglioni is a seasoned transformation leader with over 15 years of experience shaping business and digital change, consistently delivering service excellence and measurable impact. As an Associate Partner at Forward, he is recognized for his strategic vision, operational expertise, and ability to drive sustainable growth. A respected keynote speaker and host of the well-known global podcast Business Transformation Pitch with the CX Goalkeeper, Gregorio energizes and inspires organizations worldwide with his customer-centric approach to innovation. Follow Gregorio Uglioni on Linkedin: https://www.linkedin.com/in/gregorio-uglioni/ Podcast webpage: https://www.cxgaolkeeper.com/podcast

Death in tabletop RPGs is a lot like a group project: everyone insists they're prepared for it, nobody actually reads the rules, and somehow it's always the wizard's fault. In this episode, the RPGBOT crew stares straight into the great beyond—death saves, dying conditions, resurrection magic, and those awkward moments when the cleric checks their spell slots and quietly says, "So… about that body." Whether your character goes out in a blaze of glory or bleeds out behind a crate because no one had an action left, we're breaking down how death really works at the table—and how to make it memorable instead of miserable. Show Notes Character death is one of the most emotionally charged—and mechanically misunderstood—parts of tabletop roleplaying games. In this episode of the RPGBOT.Podcast, the hosts dig into how death mechanics work across popular systems, why they often feel harsher (or softer) than intended, and how players and GMs can turn character death into a powerful storytelling moment instead of a buzzkill. The discussion covers death saves, dying conditions, instant death effects, and the role of healing magic in prolonging—or preventing—the inevitable. The crew examines how different RPG systems handle mortality, from forgiving safety nets to brutal attrition-based designs, and what those choices say about the kind of stories those games want to tell. Beyond raw mechanics, the episode explores meaningful death: heroic sacrifices, last stands, narrative consequences, and when resurrection magic enhances the story versus when it cheapens the moment. The hosts also share table-tested advice for GMs on foreshadowing danger, setting expectations, and making sure character death feels fair—even when it's devastating. If you've ever wondered whether death should be rare, frequent, reversible, or permanent—or why every party suddenly becomes a tactical mastermind the moment someone drops to zero HP—this episode is for you. Key Takeaways Death mechanics shape tone. How a system handles dying directly affects whether the game feels heroic, gritty, or forgiving. Death saves are drama engines. They create tension, spotlight teamwork, and often reveal who really read their character sheet. Instant death is rare—but memorable. When it happens, it should feel earned, telegraphed, or narratively significant. Resurrection is a storytelling tool. Bringing a character back should have consequences, costs, or complications to preserve emotional weight. Heroic sacrifice beats random loss. Deaths tied to player choice are almost always more satisfying than unlucky math. GM communication matters. Clear expectations about lethality prevent resentment and help players invest emotionally. Death doesn't end the story. It can launch new arcs, reshape the party, or permanently change the world. Welcome to the RPGBOT Podcast. If you love Dungeons & Dragons, Pathfinder, and tabletop RPGs, this is the podcast for you. Support the show for free: Rate and review us on Apple Podcasts, Spotify, or any podcast app. It helps new listeners find the best RPG podcast for D&D and Pathfinder players. Level up your experience: Join us on Patreon to unlock ad-free access to RPGBOT.net and the RPGBOT Podcast, chat with us and the community on the RPGBOT Discord, and jump into live-streamed RPG podcast recordings. Support while you shop: Use our Amazon affiliate link at https://amzn.to/3NwElxQ and help us keep building tools and guides for the RPG community. Meet the Hosts Tyler Kamstra – Master of mechanics, seeing the Pathfinder action economy like Neo in the Matrix. Randall James – Lore buff and technologist, always ready to debate which Lord of the Rings edition reigns supreme. Ash Ely – Resident cynic, chaos agent, and AI's worst nightmare, bringing pure table-flipping RPG podcast energy. Join the RPGBOT team where fantasy roleplaying meets real strategy, sarcasm, and community chaos. How to Find Us: In-depth articles, guides, handbooks, reviews, news on Tabletop Role Playing at RPGBOT.net Tyler Kamstra BlueSky: @rpgbot.net TikTok: @RPGBOTDOTNET Ash Ely Professional Game Master on StartPlaying.Games BlueSky: @GravenAshes YouTube: @ashravenmedia Randall James BlueSky: @GrimoireRPG Amateurjack.com Read Melancon: A Grimoire Tale (affiliate link) Producer Dan @Lzr_illuminati

#321 | Jess Cook, VP of Marketing at Vector, joins Dave to break down what's actually working in early-stage B2B marketing. They dig into how she thinks about attribution for brand channels, how Vector's podcast became a top marketing channel, why they created a brand mascot, and details on what content strategy is working on LinkedIn right now. They also cover shift from content leader to VP of Marketing and how to drive demand without a massive team or budget.Timestamps(03:06) - — Meet Jess Cook & What is Vector? (07:39) - — B2B Influencer pilot setup: why this channel, why now (14:57) - — The result: 45 demos, ~$1.1M pipeline, and how she tracked it (16:55) - — How to run influencers (22:20) - — Scaling idea: retainer-style influencer partnerships (26:00) - — Vector's podcast: “awareness magnet” and the format that works (28:24) - — The production system: in-person batch recording a full season in 2 days (42:10) - — Jess's LinkedIn strategy: why she started posting and what she optimizes for (53:58) - — Content → VP shift: the two muscles she's building (metrics + leadership) Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Have an idea or tip? Send us a text!A 1938 basement lab that processed black-and-white alongside amateur rolls now runs a high-speed digital operation that can ship school orders in about two days. The Dead Pixels Society sits down with Richmond Professional Lab's Ted Bullard and Josh Lewis to map the decisions that made digital not just viable, but superior, for volume photographers who demand both quality and speed.Bullard recounts how Kodak's consent decree opened the processing market and how Richmond leaned into professional work, long-roll film, and eventually early digital printers. Then Lewis pulls back the curtain on the operational engine: why fewer, faster machines beat a fleet of minis, how custom software gangs tens of thousands of orders, and why posting live turnaround times builds trust during peak seasons. They share into the Canon DreamLabo journey, HP ink and laminate advances, and the color fidelity and longevity that finally matched—then surpassed—silver halide expectations.The volume landscape is shifting fast, with independents stepping in where a major player receded. That opens space for smarter products and sharper margins: yard signs, big head cutouts, layered graphics, and ship-to-home convenience that schools and parents now prefer. We talk daPhoto Imaging CONNECTThe Photo Imaging CONNECT conference, March 1-2, 2026, at the RIO Hotel and Resort in Las Vegas, NMaking Good: Small Business Marketing PodcastMaking Good helps you do better marketing so you can make a bigger impact. If you're...Listen on: Apple Podcasts SpotifyMediaclipMediaclip strives to continuously enhance the user experience while dramatically increasing revenue.Buzzsprout - Let's get your podcast launched!Start for FREEIndependent Photo ImagersIPI is a member + trade association and a cooperative buying group in the photo + print industry.Photo Imaging CONNECTThe Photo Imaging CONNECT conference, March 1-2, 2026, at the RIO Hotel and Resort in Las Vegas, NDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showSign up for the Dead Pixels Society newsletter at http://bit.ly/DeadPixelsSignUp.Contact us at gary@thedeadpixelssociety.comVisit our LinkedIn group, Photo/Digital Imaging Network, and Facebook group, The Dead Pixels Society. Leave a review on Apple and Podchaser. Are you interested in being a guest? Click here for details.Hosted and produced by Gary PageauAnnouncer: Erin Manning

While many people talk about mentorship, HP's Chief IP Counsel Ceyda Maisami and Tradespace's VP of IP Operations & Client Success Marcia Chang actually live it.In this episode, Ceyda and Marcia join Clause 8 host Eli Mazour for a wide-ranging conversation about mentorship, what it really takes to run IP teams inside large technology companies, and what the rise of AI means for both in-house and outside counsel.They share the story of how they first met at HP, why Ceyda credits Marcia with the advice and encouragement that helped her grow into the Chief IP Counsel role, and what that guidance looks like in practice for other in-house lawyers navigating their own careers.The conversation also dives into HP's experience with high-stakes litigation and how those lessons shape its global patent portfolio strategy. Ceyda also offers a behind-the-scenes look at HP's IP team restructure—why early attempts fell short and what finally made the new model work. The discussion delivers practical takeaways for anyone building or leading an in-house IP team, balancing portfolio development with business goals, or working to make IP more central to company decisions.The episode closes with a candid, practical discussion of AI—what it means for the expectations placed on outside counsel, how in-house teams are already using it, and what lawyers need to do to continue delivering real value as the pace of work accelerates.Together, Ceyda and Marcia offer a rare, grounded look at mentorship, leadership, and the future of IP inside major tech companies.

Callum McMenamin (OpenAccess) joins host Paul Spain to unpack Manage My Health data breach, exploring critical shortcomings in cybersecurity and the lack of mandatory multi-factor authentication. They also cover Kereru.ai's sovereign AI project with SCX.ai, plus CES 2026 highlights including gadgets, LG's CLOiD chore robot, LEGO's sensor‑packed Smart Bricks, Boston Dynamics' production Atlas, Intel's Core Ultra Series 3 comeback bid, Nvidia's Alpamayo autonomous driving platform and CES 2026 “Worst in Show”. Plus Kindle Colorsoft review and more.Thanks to our Partners One NZ, Workday, 2degrees, HP, Spark and Gorilla Technology

Analyse des principales actualités technologiques CES 2026 : innovations marquantes comme les écrans extensibles, les aspirateurs robots, les lunettes connectées, avec un regard critique sur certaines technologies inutiles. Évaluation des promesses d'Apple autour d'un Creator Studio, des enjeux liés à l'intelligence artificielle et à la désinformation, ainsi que de l'influence d'Elon Musk.  Patreon YouTube Discord Interactions, suivis et à chaud Les frigos jettent un froid. “Clarifications” du dernier épisode d'Office Apple Creator Studio Ça, CES fait CES finis : le bilan de la cuvée 2026 ? Whoa, Blackberry, bam-ba-lam ! Les ordinateurs portables du CES : toujours plus ! Lenovo (qui n'a pas lu Death Note) met Qira dans ses machines. Intel veut son Z1 Extreme et du HDR partout ! HP nous fait un CPC. Les lunettes, c'est trop chouette ! Mmmm Donut ! La révolution arrive, sur deux roues. Et sinon l'écologie tout ça ? Les aspirateurs du CES toujours plus robotiques. Métro boulot, robot : Atlas à l'usine, Wall-E en vrai et Unitree au dojo. Le Pire du Salon : les abominations Les batteries… avec économiseur d'écran. Un casque audio… avec des caméras. Chatgtpop : collectionnez les tous ! Et brûlez-les. Tableau d'horreur : TCL se lance dans la TV “artistique”. Le Pire du Salon : la sélection de Satan Lollipop star : la sucette qui chante dans ta bouche. Les vélos sont des iPhone comme les autres. Et aussi le tapis de marche mouchard, l'app Store de Ring et le frigo vocal. C'est déjà 2049 : Emily pas encore in Paris. À mines et à Police ICE, VenezuelIA : internet devient un champ de mines. Image pédo : une réponse de X “en demi-teinte”. Elon a beaucoup trop fumé… Jeux vidéo GameStop, le nouveau Tesla. Le prix de la Steam Machine pourrait donner des vapeurs. Toss a coin to your witcher : un nouveau DLC pour… The Witcher 3. Participants Une émission préparée par Guillaume Poggiaspalla Présenté par Guillaume Vendé

出演者：藤原鞠菜 配信ペース：隔週火曜日 番組時間：平均40分 ——————————————————————— ＜各テーマ紹介＞配信されるテーマは回によって異なります。 「ふつおた」･･･何でもありのお便りコーナー。投稿は毎日募集中！！！！！ 「歴史秘話ウィステリア」･･･サークル曲の裏話など。 「まりにゃのこれな～んだ？」･･･音当てクイズ。 「まりにゃのオススメ」･･･オススメ商品をご紹介。 「はじおと」･･･「音楽」×「初めて」に関して語るコーナー。 （初めて買ったCD、初めて心を動かされた音楽、初めてカラオケで歌った曲等。） 「これかた」･･･テーマを決めて語る割とフリーダムなコーナー。 （テーマや語ってみた投稿募集中。） 「答えて、まりにゃ」･･･まりにゃへの質問募集中。 「トレンドなう」･･･収録時に開いたTwitterのリアルタイムトレンドについてコメント。 「まりにゃのTOP5」･･･思いついたら勝手にランキング。 「まりにゃのドキドキ質問箱」…twitter投稿になります。（ https://peing.net/marinya_）  「みんなの答え合わせ」…twitterで出題するアンケートの結果報告。みんなに聞きたいこと募集中。 ——————————————————————— ——————————————————————— ■CD新作・出演告知など■ ★Wisteria Magic通販サイト「うぃすましょっぷ」★ wismashop.booth.pm/ 新作も旧作も全て送料込み！ ★イオシスショップ様にて一部旧作を委託販売中！★ www.iosysshop.com/SHOP/list.php?Search=wisteria ★しがないレコーズのyoutube「しがない5分ショー」に出演してます。 藤原鞠菜は木曜日担当です。 https://www.youtube.com/channel/UCA_FmkoMu24R_6o3m3_Ulqg —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ・の〜すとらいく様の18禁PCゲーム 「女装百合畑/Trap Yuri Garden」にて、主題歌「優雅にヒロイン宣言」を担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして！夜までもっとエッチして！」 にて女未こはくちゃん(三女)のED曲担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして!」 にて女未こはくちゃん(三女)のED曲を担当させて頂きました。 —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ——————————————————————— この番組は音楽サークルWisteria Magicがお届けする番組です。 藤原鞠菜やサークルの過去または最新の活動内容につきましては 以下をチェックしてくださると嬉しいです♪ ・藤原鞠菜のTwitter（ twitter.com/marinya_ ） ・藤原鞠菜のHP「ふじわらんど」（ fujimari.com/ ） ・磯村カイのTwitter（ twitter.com/isomurakai ） ・磯村カイのHP「TONAKAI soundworks」（ https://soundworks.tonakaii.com/ ） 藤原鞠菜への贈り物の宛先 〒107-0052 東京都港区赤坂4-9-25 新東洋赤坂ビル10F レイズイン　アカデミー気付　藤原鞠菜宛 VOICEVOX:ずんだもん VOICEVOX:四国めたん

Stage Eight of the Dakar Rally 2026 pushes the field deeper into the second half of the rally, delivering a long and demanding day that places equal emphasis on navigation, tire management, and strategy.In this Stage 8 briefing, Victor Orellana breaks down a 721-kilometer day, featuring a challenging mix of dirt tracks, sand, and rocky sections that continue to test both riders and machines. With stony terrain already proving tough on tires this year, durability and decision-making become critical.Navigation plays a major role once again, with alternating tracks and HP navigation sections that can quickly catch competitors out. Combined with the introduction of mid-stage tire changes, Stage 8 rewards those who manage pace intelligently rather than pushing blindly.This episode covers:Full Stage 8 course overviewTerrain mix and what it means for speed and fatigueWhy navigation accuracy is decisiveTire management challenges on stony tracksTiming details, including the early 5:10 AM bike startStrategic considerations as Dakar 2026 moves into its later stagesStage 8 may not look extreme on paper, but like many Dakar stages, it's designed to punish in subtle ways. As the rally progresses, preparation and discipline matter more than ever.

#320 | Matt Carnevale, Head of Community at Exit Five, joins Dave for a discussion about community building. They dive into a bunch of the lessons learned from building the Exit Five community over the last few years, including specific plays like onboarding, matchmaking, and moderation. If you're thinking about community building in 2026, this is a good primer; plus the guys give their opinion on what “community” actually means and whether you should build a private community like Exit Five or focus more broadly on community building.Timestamps(00:02) - – Matt's path from BDR to Head of Community at Exit Five (08:29) - – What “community” actually means (and what it definitely isn't) (13:14) - – Why most B2B communities fail before they ever get traction (17:54) - – Community vs. content: what gets people in vs. what makes them stay (22:29) - – Why Slack groups aren't a strategy (27:14) - – Treating community like a product, not a marketing channel (34:48) - – The role of trust, curation, and saying no to the wrong people (40:23) - – What community managers actually do behind the scenes (47:18) - – How in-person events changed the Exit Five community (53:28) - – The biggest lessons Matt's learned after two years building Exit Five Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

In this episode, Mike “C-Roc” sits down with Chris Christensen, creator of AmateurTraveler.com, Podcasting Hall of Fame inductee, and one of the true pioneers of modern podcasting. With more than 20 years behind the mic, Chris shares how curiosity has been the defining force of his life—from his early career in high tech and web development at companies like HP, IBM, and TripAdvisor, to launching one of the world's longest-running and most downloaded travel podcasts, which reached over 1.78 million downloads in 2024 alone. The conversation explores the evolution of technology, podcasting, and AI, with Chris offering thoughtful insight into how innovation has changed over the decades and where it's headed next. He also reflects on how a childhood spent road-tripping to national parks sparked a lifelong passion for travel, ultimately leading him to interview travelers from around the world and experience destinations many only dream of. Equal parts thoughtful, informative, and inspiring, this episode reveals what Chris Christensen is truly made of—and how curiosity can shape an extraordinary career andWebsite: https://AmateurTraveler.com Social Media Links/Handles-https://www.instagram.com/chris2x/?hl=enhttps://www.tiktok.com/@amateurtraveler

CES 2026 brought notable innovations for filmmakers and media professionals. In this episode, we break down the most interesting tech: Fujifilm's new instax mini Evo Cinema Camera with vintage film emulation, LEGO's impressive computer-integrated Smart Brick, HP's EliteBoard keyboard computer, Boston Dynamics' fully electric Atlas robot, Samsung's thin 3D display technology, and Nvidia's Rubin platform advances. --The views and opinions expressed in this podcast are the personal views of the hosts and do not necessarily reflect the views or positions of their respective employers or organizations. This show is independently produced by VP Land without the use of any outside company resources, confidential information, or affiliations.

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Explore the most exciting announcements from CES 2026 with Steven Scott, Shaun Preece, and guest Marc Aflalo. From HP's all-in-one keyboard computer to AI-ready laptops, haptic wearables, and Braille label printers, this episode dives into the real-world impact of emerging tech for both mainstream and accessible use.This episode is supported by Pneuma Solutions. Creators of accessible tools like Remote Incident Manager and Scribe. Get $20 off with code dt20 at https://pneumasolutions.com/ and enter to win a free subscription at doubletaponair.com/subscribe!CES 2026 delivered everything from cutting-edge laptops and AI-driven devices to innovative accessibility tools. Steven, Shaun, and Marc discuss why HP's G1 keyboard computer could be a game-changer for blind users, and how Dell's new XPS series is stepping away from the “AI ready” branding. They also explore haptic wristbands for Meta Ray-Bans, Rokid's AR glasses, and the Mnemonic Braille Label Printer, questioning both mainstream potential and accessibility.The conversation highlights how tech marketing often misses accessibility opportunities, and why CES's new Accessibility Stage is a vital step in changing that. Plus, the team debate neural bands, AI in laptops, and the growing overlap between mainstream and assistive technologies. Find Double Tap online: YouTube, Double Tap Website---Follow on:YouTube: https://www.doubletaponair.com/youtubeX (formerly Twitter): https://www.doubletaponair.com/xInstagram: https://www.doubletaponair.com/instagramTikTok: https://www.doubletaponair.com/tiktokThreads: https://www.doubletaponair.com/threadsFacebook: https://www.doubletaponair.com/facebookLinkedIn: https://www.doubletaponair.com/linkedin Subscribe to the Podcast:Apple: https://www.doubletaponair.com/appleSpotify: https://www.doubletaponair.com/spotifyRSS: https://www.doubletaponair.com/podcastiHeadRadio: https://www.doubletaponair.com/iheart About Double TapHosted by the insightful duo, Steven Scott and Shaun Preece, Double Tap is a treasure trove of information for anyone who's blind or partially sighted and has a passion for tech. Steven and Shaun not only demystify tech, but they also regularly feature interviews and welcome guests from the community, fostering an interactive and engaging environment. Tune in every day of the week, and you'll discover how technology can seamlessly integrate into your life, enhancing daily tasks and experiences, even if your sight is limited. "Double Tap" is a registered trademark of Double Tap Productions Inc. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

#319 | Dave sits down with Jess Lytle, Head of Marketing at Exit Five, to talk about how AI is changing the job of B2B marketers and the reality of how AI is actually being adopted internally. They also cover how AI even helped Jess get her job at Exit Five and why she's become obsessed about deploying AI in marketing and really believes this is the most important martech wave yet. Timestamps(00:00) - – Goals, manifestation, and reverse-engineering outcomes (06:14) - – Meet Jess Lytle, Head of Marketing at Exit Five (08:28) - – How Jess got hired at Exit Five (webinar → DMs → job) (10:28) - – From demand gen to AI: early adoption, teaching, and Lovable (15:58) - – Why AI feels different than traditional martech (18:28) - – Content in 2026: originality, human insight, and AI distribution (29:16) - – NotebookLM: real marketing workflows and internal use cases (35:16) - – AI tools, team structure, and hybrid marketer roles (45:56) - – Working at Exit Five, founder-led marketing, and brand bets Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Dr. Monty Pal and Dr. Hope Rugo discuss advances in antibody-drug conjugates for various breast cancer types as well as treatment strategies in the new era of oral SERDs for HR-positive breast cancer. TRANSCRIPT Dr. Monty Pal: Hello, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. Monty Pal. I'm a medical oncologist and vice chair of academic affairs here at the City of Hope Comprehensive Cancer Center, Los Angeles. Today, I'm thrilled to be joined by Dr. Hope Rugo, an internationally renowned breast medical oncologist and my colleague here at City of Hope, where she leads the Women's Cancers Program and serves as division chief of breast medical oncology. Dr. Rugo is going to share with us exciting advances in antibody-drug conjugates (ADCs) that are expanding treatment options in various breast cancer types. She'll also address some of the complex questions arising in the new era of oral SERDs (selective estrogen receptor degraders) that are revolutionizing treatment in the hormone receptor-positive breast cancer space. Our full disclosures are available in the transcript of this episode.  Dr. Rugo, welcome, and thanks so much for being on the podcast today. Dr. Hope Rugo: Thank you. Pleasure to be here. Dr. Monty Pal: So, I'm going to switch to first names if you don't mind.  The first topic is actually a really exciting one, Hope, and this is antibody-drug conjugates. I don't know if I've ever shared this with you, but I actually started my training at UCLA, I was a med student and resident there, and it was in Dennis Slamon's lab. I worked very closely with Mark Pegram and a handful of others. This is right around the time I think a lot of HER2-directed therapies were really evolving initially in the clinics. Now we've got antibody-drug conjugates. Our audience is well-familiar with the mechanism there but tell us about how ADCs have really started to reshape therapy for HER2-positive breast cancer. Dr. Hope Rugo: Yeah, I mean, this is a really great place to start. I mean, we have had such major advances in breast cancer just this year, I think really changing the paradigm of treating patients. But HER2-positive disease, we've been used to having sequenced success of new agents. And I think the two biggest areas where we've made advances in HER2-positive disease, which were remarkably advanced this year in 2025, have been in antibody-drug conjugates with trastuzumab deruxtecan and with new oral tyrosine kinase inhibitors (TKIs) that have less of a target on EGFR and more on HER2, so they have an overall more tolerable toxicity profile and therefore a potentially better efficacy in the clinic. At least that's what we're seeing with these new strategies that we couldn't really pursue in the past because of toxicities of the oral TKIs. So, although our topic is ADCs, I'm going to include the TKI because it's so important in our thinking about treating HER2-positive disease. In the metastatic setting, we've seen these remarkable improvements in progression-free and overall survival in the second-line setting with T-DXd, or trastuzumab deruxtecan, compared to T-DM1. And then sequencing ADCs with giving T-DXd after T-DM1 was better than an oral tyrosine kinase or a trastuzumab combination with standard chemotherapy. That was DESTINY-Breast03 and DESTINY-Breast02. So, then we've had other trials since then, and T-DXd has moved into the early-stage setting, which I'll talk about in just a moment. But the next big trial for T-DXd in HER2-positive disease was moving it to the first-line setting to supplant what has become an established treatment for now quite a long time: the so-called CLEOPATRA regimen, which used the combined antibodies trastuzumab, pertuzumab with a taxane as first-line therapy. And then we've proceeded on with maintenance with ongoing HP for patients with responding or stable disease. And we'd seen long-term data showing, you know, at 8 years there was a group of patients whose cancers had never progressed and continued improved overall survival. So, T-DXd was studied in DESTINY-Breast09, either alone or in combination with pertuzumab compared to THP. The patient population had received a little bit more prior treatment, but interestingly, not a lot compared to CLEOPATRA. And they designed the trial to be T-DXd continued until progression with or without pertuzumab versus THP, which would go for six cycles and then stop around six cycles, and then stop and continue HP. Patients who had hormone receptor-positive disease could use hormone therapy, and this is one of the issues with this dataset because, surprisingly in this dataset and one other I'll mention, very few patients took hormone therapy. And even in the maintenance trial, the HER2CLIMB-05, less than 50% took hormone therapy as maintenance. This is kind of shocking to me and highlights an area of really important education, that outcome is improved when you add endocrine therapy for hormone receptor-positive HER2-positive metastatic disease in the maintenance phase, and it's a really important part of treatment. But suffice it to say, you know, you're kind of studying continued chemo versus stopping chemo in maintenance. And T-DXd, as we all expected, in combination with pertuzumab was superior to THP in terms of progression-free survival, really remarkably improved. And you could stop the chemo with toxicity, but most people continued it with T-DXd. Again, not a lot of people got hormone therapy, which is an issue, and you stop the chemo in the control arm. So, this has brought up a lot of interest in trying to use T-DXd as an induction and then go to maintenance, much as we do with the CLEOPATRA regimen with hormone therapy. But it brings up another issue. So first, T-DXd is superior; it's a great treatment. Not everybody needs to have it because we don't know whether it's better to give T-DXd first or second with progression - that we need a little bit longer follow-up. But just earlier this week, interestingly, the third week of December, the U.S. FDA approved T-DXd in the DESTINY-Breast09 approach with pertuzumab. So as I mentioned earlier, there was a T-DXd-alone arm; that arm has not yet reported. So very interesting, we don't know if you need pertuzumab or not. So what about the maintenance? That's the other area where we've made a huge advance here. So, we all want to stop chemo and we want to stop T-DXd. You don't want somebody being nauseated for two years while they're on treatment, and also there's a small number of patients with mostly de novo metastatic HER2-positive disease who are cured of their disease. We'd like to expand that, and I think these new drugs give us the opportunity to improve the number of patients who might be cured from metastatic disease. So the first maintenance study we saw was adding palbociclib, the CDK4/6 inhibitor, to endocrine therapy and HP, essentially. There, we had a remarkable improvement in progression-free survival difference of 15.2 months: 29 to 44 months, really huge. At San Antonio this year, we saw data with this oral tyrosine kinase inhibitor tucatinib, already showed it was great in a triplet, but as maintenance in combination with HP, it showed also a remarkable improvement in progression-free survival. But the numbers were all shifted down. So in PATINA, the control arm was in the 24-month range; here it was the tucatinib-HP arm that was in the 25 months and 16 months for control. So there was a differential benefit in ER-negative and ER-positive disease. So I think we're all thinking that our ideal approach moving forward would be to give T-DXd to most patients, we see how they do, and treat to best response. And then, stop the T-DXd, start HP, trastuzumab, pertuzumab for ER-negative, with tucatinib for ER-positive with palbociclib. We also have early data that suggests that both approaches may reduce the development of brain metastases, an issue in HER2-positive disease, and delay time to progression of brain metastases as seen in HER2CLIMB-05 in very early data - small numbers, but still quite intriguing that you might delay progression of brain metastases with tucatinib that clearly has efficacy in the brain.  So, I think that this is a hugely exciting advance for our patients, and these approaches are quickly moving into the early stage setting. T-DXd compared to standard chemo, essentially followed by THP, so a sequenced approach resulted in more pathologic complete responses than a standard THP-AC-type neoadjuvant therapy. T-DXd alone for eight cycles wasn't better, and that's interesting. We still need the sequenced non-cross-resistant chemo. But I think even more importantly, the data from DESTINY-Breast05 looking at T-DXd versus T-DM1 in patients with residual disease after neoadjuvant HER2-targeted therapy showed a remarkable improvement in invasive disease-free survival with T-DXd versus T-DM1, and quite early. It was a high-risk population, higher risk than the T-DM1 trial with KATHERINE, but earlier readout with a remarkable improvement in outcome. We expect to be FDA approved sometime in the first half of 2026. So then we'll get patients who've already had T-DXd who get metastatic disease. But my hope is that with T-DXd, maybe with tucatinib in the right group of patients or even sequenced in very high-risk disease, that we could cure many more patients with early-stage HER2-positive breast cancer and cure a subset, a greater subset of patients with de novo metastatic disease. Dr. Monty Pal: That's brilliant. And you tackled so many questions that I was going to follow up with there: brain metastases, etc. That was sort of looming in my mind. I mean, general thoughts on an ADC versus a TKI in the context of brain mets? Dr. Hope Rugo: Yeah, it's an interesting question because T-DXd has shown quite good efficacy in this setting. And tucatinib, of course, had a trial where they took patients with new brain mets, so a larger population than we've seen yet for the T-DXd trials, and saw that not only did they delay progression of brain metastases and result in shrinkage of existing untreated brain mets, but that patients who develop a new brain met, they could stay on the same assigned treatment. They got stereotactic radiation, and then the patients who were on tucatinib with trastuzumab and capecitabine had a further delay in progression of brain mets compared to those on the placebo arm, even after treatment of a new one that developed on treatment. So, I think it's hard. I think most of us for a lot of brain mets might start with the tucatinib approach, but T-DXd is also a very important treatment. You know, you're kind of trading off a diarrhea, some liver enzyme elevations with tucatinib versus nausea, which you really have to work on managing because it can be long-delayed nausea, and this risk of ILD, interstitial lung disease, that's about 12%, with most but not all trials showing a mortality rate from interstitial lung disease of just under 1 percent. In the early-stage setting, it was really interesting to see that with T-DXd getting four cycles in the neoadjuvant setting, a lot less ILD noted than the patients who got up to 14 cycles, as I think they got a median of 10 cycles in the post-surgical setting, there was a little bit more ILD. But I think we're going to be better and better at finding this earlier and preventing mortality by just stopping drug and treating earlier with steroids. Dr. Monty Pal: And this ILD issue, it always seems to resurface. There are drugs that I use in my kidney cancer clinic, everolimus, common to perhaps the breast cancer clinic as well, pembrolizumab, where I think the pattern of pneumonitis is quite different, right? What is your strategy for recognizing pneumonitis early in this context? Dr. Hope Rugo: Well, it is, and you know, having done the very early studies in everolimus where we gave it in the neoadjuvant setting and we're like, "Hmm, the patient came in with a cough. What's going on?" You know, we didn't know. And you have mouth sores, you know, we were learning about the drug as we were giving it. What we don't do with everolimus and CDK4/6 inhibitors, for example, is grade 1 changes like radiation pneumonitis, we don't stop, we don't treat it. We only treat for symptoms. But because of the mortality associated with T-DXd, albeit small, we stop drug for grade 1 imaging-only asymptomatic pneumonitis, and some of us treat with a half dose of steroids just to try and hasten recovery. We've actually now published or presented a couple of datasets from trials, a pooled analysis and a real-world analysis, that have looked at patients who were retreated after grade 1 pneumonitis or ILD and tolerated drug very well and none of them died of interstitial lung disease, which was really great to see because you can retreat safely and some of these patients stayed on for almost a year benefiting from treatment. So, there's a differential toxicity profile with these drugs and there are risk factors which clearly have identified those at higher risk: prior ILD, for example. A French group said smoking; other people haven't found that, maybe because they smoked more in France, I don't know. And being of Japanese descent is quite interesting. The studies just captured that you were treated in Japan, but I think it's probably being of Japanese descent with many drugs that increases your risk of ILD. And, you know, older patients, people who have hypoxia, those are the patients. So, how do we do this? With everolimus, we don't have specific monitoring. But for T-DXd we do; we do every nine weeks to start with and then every 12 weeks CT scans because most of the events occur relatively early. Somebody who's older and at higher risk now get the first CT at six weeks. Dr. Monty Pal: This is super helpful. And I have to tell you, a lot of these drugs are permeating the bladder cancer space which, you know, is ultimately going to be a component of my practice, so thank you for all this. We could probably stay on this topic of HER2-positive disease forever. I'm super interested in that space still. But let me shift gears a little bit and talk about triple-negative breast cancer and this evolving space of HR-positive, HER2-low breast cancer. I mean, tell us about ADCs in that very sort of other broad area. Dr. Hope Rugo: So triple-negative disease is the absolute hardest subset of disease that we have to treat because if you don't have a great response in the early stage setting, the median survival is very short, you know, under two years for the majority of TNBCs, with the exception of the small percentage of low proliferative disease subsets. The co-question is what do we do for these patients and how do we improve outcome? And sacituzumab govitecan has been one strategy in the later line setting that was shown to improve progression-free and overall survival, the Trop-2 ADC. We had recently three trials presented with the two ADCs, sacituzumab govitecan and the other Trop-2 ADC that's approved for HR-positive disease, datopotamab deruxtecan. And they were studied in the first-line setting. Two trials with SG, sacituzumab govitecan, those trials, one was PD-L1 positive, ASCENT-04. That showed that SG with a checkpoint inhibitor was superior, so pembrolizumab was superior to the standard KEYNOTE-355 type of treatment with either a taxane or gemcitabine and carboplatin with pembrolizumab for patients who have a combined positive score for PD-L1, 10 or greater. So, these are patients who are eligible for a checkpoint inhibitor, and SG resulted in an improved progression-free survival.  The interesting thing about that dataset is that few patients had received adjuvant or neoadjuvant checkpoint inhibitor, which is fascinating because we give it to everybody now. But access is an issue and timing of the study enrollment was an issue. The other thing which I think we've all really applauded Gilead for is that there was automatic crossover. So, you could get from the company, to try and overcome some of the enormous disparities worldwide in access to these life-saving drugs, you could get SG through the company for free once you had blinded independent central review confirmation of disease progression. Now, a lot of the people who got the SG got it through their insurance, they didn't bill the company, but 80 percent of patients in the control arm received SG in the second-line setting. So that impacts your ability to look at overall survival, but it's an incredibly important component of these trials. So then at ESMO, we saw the data from SG and Dato-DXd in the first-line metastatic setting for patients who either had PD-L1-negative disease or weren't eligible for an immunotherapy. For the Dato study, TROPION-Breast02, that was 10 percent of the patients who had PD-L1-positive disease but didn't get a checkpoint inhibitor, and for the ASCENT-03 trial population it was only 1 percent. Importantly, the trials allowed patients who relapsed within a year of receiving their treatment with curative intent, and the Dato study, TB-02, allowed patients who relapsed while on treatment or within the first six months, and that was 15 percent of the 20 percent of early relapsers. The ASCENT trial, ASCENT-03, had 20 percent who relapsed between 6 and 12 months. The drugs were better than standard of care chemotherapy, the ADCs in both trials, which is very nice. Different toxicity profiles, different dosing intervals, but better than standard of care chemotherapy in the disease that's hardest for us to treat. And importantly, when you looked at the subset of early relapsers, those patients also did better with the ADC versus chemotherapy, which is incredibly important. And we were really interested in that 15 percent of patients who had early relapse. I actually think that six months thing was totally contrived, invented, you know, categorization and doesn't make any sense, and we should drop it. But the early relapsers were 15 percent of TB-02 and Dato was superior to standard of care chemo. We like survival, but the ASCENT trial again allowed the crossover to an approved ADC that improved survival and 80 percent of patients crossed over. In the Dato trial, they did not allow crossover, they didn't provide Dato, which isn't approved for TNBC but is for HR-positive disease, and they didn't allow, of course, pay for SG. So very few patients actually crossed over in their post-treatment data and in that study, they were able to show a survival benefit. So actually, I think in the U.S. where we can use approved drugs already before there's a fixed FDA approval, that people are already switching to use SG or Dato in the first-line setting for metastatic TNBC that's both PD-L1 positive for SG and PD-L1 negative for both drugs. And I think understanding the toxicity profiles of the two drugs is really important as well as the dosing interval to try and figure out which drug to use. Dr. Monty Pal: Brilliant. Brilliant. Well, I'm going to shift gears a little bit. ADCs are a topic, again, just like HER2-positive disease we could stay on forever. Dr. Hope Rugo: Huge. Yes. Dr. Monty Pal: But we're going to shift gears to another massive topic, which is oral SERDs. In broad strokes, right, this utilization of CDK4/6 inhibitors in the context of HR-positive breast cancer is obviously, you know, a paradigm that's been well established at this point. Where do we sequence in oral SERDs? Where do they fit into this paradigm? Dr. Hope Rugo: Ha! This is a rapidly changing area; we keep changing what we're saying every other minute. And I think that there are three areas of great interest. So one is patients who develop ESR1 mutations that allow constitutive signaling through the estrogen receptor, even when there's not estrogen around, and that is a really important mutation that is subclonal; it develops under the pressure of treatment in about 40 percent of patients. And it doesn't happen when you first walk in the door. And what we've seen is that oral SERDs as single agents are better than standard single-agent endocrine therapy in that setting. The problem that we've had with that approach is that we're now really interested in giving targeted agents with our endocrine therapies, not just in the first-line setting where CDK4/6 inhibitors are our standard of care with survival benefit for ribociclib and, you know, survival benefit in subsets with other CDK4/6 inhibitors, and abemaciclib with a numeric improvement. So we give it first line. The question is, what do you do in the second-line setting? Because of the recent data, we now believe that oral SERDs should be really given with a targeted agent. And some datasets which were recently presented, which I think have helped us with that, have been EMBER-3 and then the most recently evERA BC, or evERA Breast Cancer, that looked at the oral SERD giredestrant with everolimus compared to standard of care endocrine therapy with everolimus, where 100 percent of patients received prior CDK4/6 inhibitor and showed a marked improvement in progression-free survival, including in the subsets of patients with a short response, 6-12 months of prior response to CDK4/6 inhibitor and in those who had a PIK3CA pathway mutation. The thing is that the benefit looks like it's much bigger in the ESR1 mutant population, although response was better, PFS wasn't better in the wild type. So, we're still trying to figure that out. We also saw EMBER-3 with imlunestrant and abemaciclib as a second line. Not everybody had had a prior CDK4/6 inhibitor; they compared it to imlunestrant alone, but still the data was quite striking and seemed to cross the need for ESR1 mutations. And then lastly, we saw data from the single arms of the ELEVATE trial looking at elacestrant with everolimus and abemaciclib and showed these really marked progression-free survival data, even though single-arm, that crossed the mutation status. At least for the everolimus combination, abemaciclib analysis is still to come in the mutated subgroups. But really remarkable PFS, much longer.  Single-agent fulvestrant after CDK4/6 inhibitor AI has a PFS in like the three-month range and in some studies, maybe close to five months. These are all at 10-plus months and really looking very good. And so those questions are, is it ESR1 mutation alone? Is it all comers? We'd like all comers, right? We believe in the combination approach and we're learning more about combinations with drugs like capivasertib and other drugs as we move forward. Everybody now wants to combine their targeted agent with an oral SERD because they're clearly here to stay with quite remarkable data. The other issue, so the second issue in the metastatic setting is, does it make a difference if we change to an oral SERD before radiographic imaging evidence of progression? And that was the question asked in the SERENA-6 trial where patients had serial monitoring for the presence of ESR1 mutations in ctDNA. And those who had them without progression on imaging could be randomized to switch to camizestrant with the same CDK4/6 inhibitor or stay on their same AI CDK4/6 inhibitor. And they showed a difference in progression-free survival that markedly favored camizestrant. But interestingly, the people who were on the standard control arm had an ESR1 mutation, we think AIs don't work, they stayed on for nine more months. The patients who were on the camizestrant stayed on for more than 16 months. And they presented some additional subset data which showed the same thing: follow-up PFS data, PFS2, all beneficial in SERENA-6 at the San Antonio [Breast Cancer Symposium]. So, we're still a little bit unclear about that. They did quality of life, and pain was markedly improved. They had a marked delayed time to progression of pain in the camizestrant arm. So this is all a work in progress, trying to understand who should we switch without progression to an oral SERD based on this development of this mutation that correlates with resistance. And, you know, it's interesting because the median time to having a mutation was 18 months and the median time to switch was almost 24 months. And then there were like more than 3,000 patients who hadn't gotten a mutation, hadn't switched, and were still okay. So screening everybody is the big question, and when you would start and who you would change on and how this affects outcome. Patients didn't have access to camizestrant in the control arm, something we can't fix but we have experimental drugs. We're actually planning a trial, I hope in collaboration with the French group Unicancer, and looking at this exact question. You know, if you switch and you change the CDK4/6 inhibitor and then you also allow crossover, what will we see? Dr. Monty Pal: We're coming right to the tail end of our time here, and I could probably go on for another couple of hours with you here. But if you could just give us maybe one or two big highlights from San Antonio, any thoughts to leave our audience with here based on this recent meeting? Dr. Hope Rugo: Yeah, I mean, I talked about a lot of those new data already from San Antonio, and the one that I'd really like to mention which I think was, you know, there were a lot of great presentations including personalized screening presented from the WISDOM trial by my colleague Laura Esserman, fascinating and really a big advance. But lidERA was the big highlight, I think, outside of the HER2CLIMB-05 which I talked about earlier in HER2-positive disease. And this study looked at giredestrant, the oral SERD versus standard of care endocrine therapy as treatment for medium and high-risk early-stage breast cancer. And what they showed, which I think was really remarkable with just about a three-year median follow-up, was an improvement in invasive disease-free survival with a hazard ratio of 0.7. I mean, really quite remarkable and so early. It looked as though this was all driven by the high-risk group, which makes sense, not the medium risk, it's too early. And also that there was a bigger benefit in patients who were on tamoxifen compared to giredestrant versus AI, but for both groups, the confidence intervals didn't cross 1. There's even a trend towards overall survival, even though it's way too early. I think that, you know, really well-tolerated oral drug that could improve outcome in early-stage disease, this is the first advance we've seen in over two decades in the treatment of early-stage hormone receptor-positive disease with just endocrine therapy. I think we think that we don't want to give up CDK4/6 inhibitors because we saw a survival benefit with abemaciclib and a trend with giving ribociclib in the NATALEE trial. So we're thinking that maybe one approach would be to give CDK4/6 inhibitors and then switch to an oral SERD or to have enough data to be able to give oral SERDs with these CDK4/6 inhibitors for early-stage disease. And that's all in the works, you know, lots of studies going on. We're going to see a lot of data with both switching 8,000 patients with an imlunestrant switching trial, an elacestrant trial going on, and safety data with giredestrant with abemaciclib and soon to come ribociclib. So, this is going to change everything for the treatment of early-stage breast cancer, and I hope cure more patients of the most common subset of the most common cancer diagnosed in women worldwide. Dr. Monty Pal: Super exciting. It's just remarkable to hear how this has evolved since 25 years ago, which is really the last time I sort of dabbled in breast cancer.  Thank you so much, Hope, for joining us today. These were fantastic insights. Appreciate you being on the ASCO Daily News Podcast and really want to thank you personally for your remarkable contribution to the field of breast cancer. Dr. Hope Rugo: Thank you very much, and thanks for talking with me today. Dr. Monty Pal: You got it. And thanks a lot to our listeners today as well. You'll find links to all the studies we discussed today in the transcript of this episode. Finally, if you value the insights that you hear today on the ASCO Daily News Podcast, please rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinion of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Follow today's speakers:   Dr. Monty Pal @montypal Dr. Hope Rugo   @hoperugo Follow ASCO on social media:        ASCO on X  ASCO on Bluesky       ASCO on Facebook        ASCO on LinkedIn        Disclosures:     Dr. Monty Pal:    Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview   Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical   Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis   Dr. Hope Rugo:    Honoraria: Mylan/Viatris, Chugai Pharma   Consulting/Advisory Role: Napo Pharmaceuticals, Sanofi, Bristol Myer   Research Funding (Inst.): OBI Pharma, Pfizer, Novartis, Lilly, Merck, Daiichi Sankyo, AstraZeneca, Gilead Sciences, Hoffman La-Roche AG/Genentech, In., Stemline Therapeutics, Ambryx  

Ce jeudi 8 janvier, François Sorel a reçu Bruno Guglielminetti, journaliste et animateur de "Mon Carnet de l'actualité numérique", et Jérôme Colombain, journaliste et créateur du podcast « Monde Numérique ». Ils se sont penchés sur la grande présence de la Chine pendant la CES 2026, la présentation du SUV électrique de Sony et Honda, les démonstrations sur la voiture autonome pendant la CES 2026, la présentation des produits de Lenovo à la Sphère, le nouveau clavier de HP, l'utilisation de la technologie au service de l'inclusion, ainsi que le cadre photo dopé à l'IA qui donne vie aux images, dans l'émission Tech & Co, la quotidienne, sur BFM Business. Retrouvez l'émission du lundi au jeudi et réécoutez la en podcast.

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

Listen to a recap of the top stories of the day from 9to5Mac. 9to5Mac Daily is available on iTunes and Apple's Podcasts app, Stitcher, TuneIn, Google Play, or through our dedicated RSS feed for Overcast and other podcast players. Sponsored by 9to5Mac Daily Plus: Get ad-free versions of every episode by visiting 9to5mac.com/join.  New episodes of 9to5Mac Daily are recorded every weekday. Subscribe to our podcast in Apple Podcast or your favorite podcast player to guarantee new episodes are delivered as soon as they're available. Stories discussed in this episode: iPadOS 26.2 and macOS 26.2 unlock faster Wi-Fi on select devices Dell, HP, and Lenovo opposing Apple trend with new laptop designs Leaker suggests future iPhones could get multispectral cameras New iPhone with 200MP camera gets release timing update Listen & Subscribe: Apple Podcasts Overcast RSS Spotify TuneIn Google Podcasts Subscribe to support Chance directly with 9to5Mac Daily Plus and unlock: Ad-free versions of every episode Bonus content Catch up on 9to5Mac Daily episodes! Don't miss out on our other daily podcasts: Quick Charge 9to5Toys Daily Share your thoughts! Drop us a line at happyhour@9to5mac.com. You can also rate us in Apple Podcasts or recommend us in Overcast to help more people discover the show.

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

Discover the latest accessible tech trends from CES 2026, including HP's groundbreaking EliteBoard G1 keyboard PC, Dell's refreshed XPS laptops, and the growing challenges of RAM shortages caused by AI demand. Steven Scott and Shaun Preece discuss how these innovations impact blind users, why some “accessible” products miss the mark, and the surprising rise of computer-in-a-keyboard devices.In this Double Tap episode, Steven and Shaun break down the biggest headlines from CES in Las Vegas. They explore HP's EliteBoard G1, a full PC built into a keyboard, and discuss why it could be a game-changer for blind users looking for portable, all-in-one solutions. The conversation also covers Dell's XPS revival with physical function keys, the looming PC price hikes due to RAM shortages, and the growing demand for AI-ready devices. The hosts also critique accessibility in mainstream tech, highlighting frustrations with Elgato and RØDE software and the difference between intentional and accidental accessibility. Listener emails bring personal stories about guide dog training, BitLocker workarounds, and voice assistant tips for iPhone and Android.Enjoying Double Tap? Subscribe for more accessible tech discussions, share your feedback at feedback@doubletaponair.com, and join the conversation on making mainstream tech work for everyone.Relevant LinksCES Official Site: https://www.ces.tech Find Double Tap online: YouTube, Double Tap Website---Follow on:YouTube: https://www.doubletaponair.com/youtubeX (formerly Twitter): https://www.doubletaponair.com/xInstagram: https://www.doubletaponair.com/instagramTikTok: https://www.doubletaponair.com/tiktokThreads: https://www.doubletaponair.com/threadsFacebook: https://www.doubletaponair.com/facebookLinkedIn: https://www.doubletaponair.com/linkedin Subscribe to the Podcast:Apple: https://www.doubletaponair.com/appleSpotify: https://www.doubletaponair.com/spotifyRSS: https://www.doubletaponair.com/podcastiHeadRadio: https://www.doubletaponair.com/iheart About Double TapHosted by the insightful duo, Steven Scott and Shaun Preece, Double Tap is a treasure trove of information for anyone who's blind or partially sighted and has a passion for tech. Steven and Shaun not only demystify tech, but they also regularly feature interviews and welcome guests from the community, fostering an interactive and engaging environment. Tune in every day of the week, and you'll discover how technology can seamlessly integrate into your life, enhancing daily tasks and experiences, even if your sight is limited. "Double Tap" is a registered trademark of Double Tap Productions Inc. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

出演者： miko、quim 配信ペース： 隔週水曜日 番組時間：95分20秒 ♯本番組はリモート収録です。 ♯収録時環境の影響により、全体的に聴き取り辛くなっております。 　申し訳ございません。 てん、てててててててん… かがみもー。2026年もマイペースなmikoラジ、第388回です。 毎年恒例、春の海チャレンジからスタートする2026年1回目。 大晦日まで働いた我さんと、しっかり連休をとったしがないさんの噛合わない年末年始。 何だかんだで、それなりご長寿番組になっても変わらぬお家れでぃお。 最後までごゆるりとお楽しみくださいませ。 ♯途中で色々とノイズ等入りますが、収録時のものです。 　ご安心ください、お手持ちの機器は正常です。 //////////////////// VOICEVOX:ずんだもん VOICEVOX:四国めたん //////////////////// -------------------- ●お便り募集中！ mikoラジでは以下の内容でお便りを募集中です！ ・ふつおた 　／普通のお便り、お待ちしています！ ・mikoは大変な絵を描いていきました 　／miko画伯に描いて欲しいお題をお待ちしています！ ・メシヲコエテ 　／料理人・mikoに教えて欲しいレシピをお待ちしています！ bit.ly/2GAWjyv 投稿フォームからラジオに投稿が出来ます！ コーナー名を選び、メッセージ・ラジオネーム・お所を入力して、 どんどん送ってください！　お待ちしています！！ ------------ 本ラジオのメインパーソナリティーである「チーム我等(miko/quim)」、 それぞれ以下個人サークルにて活動中です。 ・miko：miko ・quim：SHIGANAI RECORDS（ shiganai.com/ ） 活動詳細については、上記HPの他 各人のブログ/twitter等にて随時告知しておりますので、チェックしてみてください！ ・みころぐ。(mikoのブログ)（ ameblo.jp/miko-nyu/ ） ・@ mikonyu(mikoのtwitter)（ twitter.com/mikonyu ） ・@ quim(quimのtwitter)（ twitter.com/quim ） --- その他の活動については、以下のとおりです！ -- チーム我等がメインクルーとして活動していた「アルバトロシクス（ albatrosicks.com/ ）」、 これまでリリースしたCDは、イオシスショップ（ iosys.booth.pm/ ）にて頒布しております。ご興味ある方は是非！ ---------- ☆2025年1月IOSYSはいてない.comパワープレイ楽曲 M1. YATSUZAKI HARDCORE (Liqo NEXT100 Remix) 作曲：SHC crew リミックス：Liqo 音楽ジャンル：Hardcore 収録アルバム：YATSUZAKI HARDCORE COLLECTION 2025 2025・12・31 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-1005 変わらぬ"やりたい音"を、札幌から全世界へ！ YATSUZAKI HARDCOREが贈る2025年総まとめコンピレーション！

#318 | Dave is joined by Kieran Flanagan, SVP of Marketing at HubSpot and former CMO at Zapier. They break down how AI is reshaping B2B marketing workflows, content creation, and team structure, plus Kieran's leadership philosophy for managing a 300+ person team while staying deeply involved in creative execution. This episode offers a clear look at how AI is changing the game and how B2B marketers can stay creative, strategic, and indispensable in the process.Timestamps(00:00) - – Intro + why AI matters now (04:28) - – Kieran's career + the 2-year mission framework (09:58) - – The grind, early-career advice, and earning your stripes (12:28) - – Operator vs. manager + strong opinions in leadership (20:28) - – Why collaborative brainstorms fail (25:28) - – ChatGPT vs. Claude + how Kieran actually uses AI (33:16) - – Where AI is taking B2B marketing (answers → actions) (44:46) - – Picking a lane: technical vs. creative marketers (52:16) - – The future CMO + agencies, in-person, and what still matters Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Bernadette P is from New Jersey and she is sharing at the Fellowship of the Spirit on Step 11, specifically on the topic -  The purpose of meditation is to improve our conscious contact with HP's grace and wisdom. Recorded in May 2022. Zoom Support Sober Cast: https://sobercast.com/donate Email: sobercast@gmail.com Sober Cast has 3000+ episodes available, visit SoberCast.com to access all the episodes where you can easily find topics or specific speakers using tags or search. https://sobercast.com

Book 7, Chapter 2: In Memoriam

In this episode I'm going to do something a little different. As we wind down for the year, we're going to be running some of our favorites from 2025 until the new year begins.Let's take a look back at some of the overall themes discussed and point out a few highlights for me. I won't be able to highlight everything of course but I found 5 themes really interesting. And, I won't lie - I had a little help from AI in doing this. But that's also kind of the point. We have all been using AI to do things to make our work easier, and I thought that poring through 150+ episodes recorded over 12 months is a perfect thing to have AI help me with. About Greg Kihlström Greg Kihlström is a best-selling author, speaker, and entrepreneur, and serves as an advisor and consultant to top companies on marketing technology, marketing operations, and digital transformation initiatives. He has worked with some of the world's top brands, including Adidas, Coca-Cola, FedEx, HP, Marriott, Nationwide Insurance, Victoria's Secret, and Toyota. He is a multiple-time Co-Founder and C-level leader, leading his digital experience agency to be acquired in 2017, successfully exited an HR technology platform provider he co-founded in 2020, and led a SaaS startup to be acquired by a leading edge computing company in 2021. He currently advises and sits on the Board of a marketing technology startup.In addition to his experience as an entrepreneur and leader, he earned his MBA, is currently a doctoral candidate for a DBA in Business Intelligence, and teaches several courses and workshops as a member of the School of Marketing Faculty at the Association of National Advertisers. He has served on the Virginia Tech Pamplin College of Business Marketing Mentorship Advisory Board, the University of Richmond's CX Advisory Board, and was the founding Chair of the American Advertising Federation's National Innovation Committee.  Greg is Lean Six Sigma Black Belt certified, is an Agile Certified Coach (ICP-ACC), and holds a certification in Business Agility (ICP-BAF).  Greg Kihlström on LinkedIn: https://www.linkedin.com/in/gregkihlstrom Resources The Agile Brand Podcast: https://www.gregkihlstrom.com The Agile Brand podcast is brought to you by TEKsystems. Learn more here: https://www.teksystems.com/versionnextnow Catch the future of e-commerce at eTail Palm Springs, Feb 23-26 in Palm Springs, CA. Go here for more details: https://etailwest.wbresearch.com/ Enjoyed the show? Tell us more at and give us a rating so others can find the show at: https://ratethispodcast.com/agileConnect with Greg on LinkedIn: https://www.linkedin.com/in/gregkihlstromDon't miss a thing: get the latest episodes, sign up for our newsletter and more: https://www.theagilebrand.showCheck out The Agile Brand Guide website with articles, insights, and Martechipedia, the wiki for marketing technology: https://www.agilebrandguide.com The Agile Brand is produced by Missing Link—a Latina-owned strategy-driven, creatively fueled production co-op. From ideation to creation, they craft human connections through intelligent, engaging and informative content. https://www.missinglink.company

This week we make a few end-of-year predictions for what 2026 will hold in store for Harry Potter fans, and open up the MuggleMail bag further than ever, as we read recent comments from YouTube and Spotify in addition to Discord, voicemails and e-mail! Join Andrew, Eric, Micah and Laura for our final episode of 2025! Looking ahead: what news will we get about a Hogwarts Legacy sequel? How about the HBO TV series? Will more series be green lit? Andrew leads the group in making unhinged predictions including genderbent books and a line of adults-only official merchandise. Our own 2026 plans for MuggleCast include content that looks ahead as well as back, including more talks on the TV show and classic components of HP fandom history. Voicemails sent in include a Hermione Granger impression, and ask the question, "how do children learn Voldemort's name?" Was Arthur Weasley's originally-planned death hinted at in the text of Book 5 and before? Spotify listeners want to know: is Snape projecting? What is the general skill level of your average every day wizard? And will Micah tell more dad jokes? Is Severus Snape a good teacher? What about his old Potions book? Why doesn't Dumbledore ever tell Harry exactly how to destroy the Horcruxes? And, does Hermione belong in Ravenclaw? Additionally, folks tell us their feelings on the Full Cast Harry Potter Audiobooks as well as the Tonks and Lupin romantic subplot. Our Lynx Line segment asks our most dedicated listeners for recommendations of books they've read this year and enjoyed. See the full list of suggestions here! Bonus MuggleCast, available over on our Patreon, will have the hosts discussing their behind-the-scenes stories of contributing to MuggleNet.com MuggleCast will return January 12, 2026! Learn more about your ad choices. Visit megaphone.fm/adchoices